FB2021_01, released Feb 18, 2021

Gene: Dmel\mt:tRNA:Glu-TTC

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General Information
Symbol
Dmel\mt:tRNA:Glu-TTC
Species
D. melanogaster
Name
mitochondrial transfer RNA:Glutamic acid-TTC
Annotation Symbol
CR34081
Feature Type
tRNA_gene
FlyBase ID
FBgn0013692
Gene Model Status
Current
Stock Availability
None publicly available
Other Summaries
Key Links
Genomic Location
Cytogenetic map
Sequence location
mitochondrion_genome:6,259..6,325 [+]
Recombination map
RefSeq locus
NC_024511 REGION:6259..6325
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (0 terms)
Molecular Function (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
    -
    Summaries
    Gene Group (FlyBase)
    MITOCHONDRIALLY ENCODED TRANSFER RNAS -
    Transfer RNAs encoded by the mitochondrial genome (mt tRNAs) function as adaptor molecules in the translation of mitochondrially encoded polypeptides from mRNA by mitoribosomes. tRNAs are approximately 80 nucleotides in length and have two regions of fundamental functional importance: the anticodon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's cognate amino acid is attached. (Adapted from SO:0000253, PMID:25734984 and PMID:26549858.)
    Gene Model and Products
    Number of Transcripts
    1
    Number of Unique Polypeptides
    0

    Please see the JBrowse view of Dmel\mt:tRNA:Glu-TTC for information on other features

    To submit a correction to a gene model please use the Contact FlyBase form

    Protein Domains (via Pfam)
    Isoform displayed:
    Pfam protein domains
    InterPro name
    classification
    start
    end
    Protein Domains (via SMART)
    Isoform displayed:
    SMART protein domains
    InterPro name
    classification
    start
    end
    Comments on Gene Model
    Sequence Ontology: Class of Gene
    mt_gene
    tRNA_gene
    Transcript Data
    Annotated Transcripts
    Name
    FlyBase ID
    RefSeq ID
    Length (nt)
    mt:tRNA:Glu-TTC-RA
    FBtr0100875
    67
    Additional Transcript Data and Comments
    Reported size (kB)
    Comments
    External Data
    Crossreferences
    Sequences Consistent with the Gene Model
    Nucleotide / Polypeptide Records
      Mapped Features

      Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mt:tRNA:Glu-TTC using the Feature Mapper tool.

      External Data
      Crossreferences
      Linkouts
      Expression Data
      Expression Summary Ribbons
      Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
      For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
      Transcript Expression
      Additional Descriptive Data
      Marker for
       
      Subcellular Localization
      CV Term
      Polypeptide Expression
      Additional Descriptive Data
      Marker for
       
      Subcellular Localization
      CV Term
      Evidence
      References
      Expression Deduced from Reporters
      High-Throughput Expression Data
      Associated Tools

      GBrowse - Visual display of RNA-Seq signals

      View Dmel\mt:tRNA:Glu-TTC in GBrowse 2
      Bulk Downloads
      RNA-Seq RPKM values for all genes
      Reference
      See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
      Developmental Proteome: Life Cycle
      Developmental Proteome: Embryogenesis
      External Data and Images
      Alleles, Insertions, Transgenic Constructs, and Aberrations
      Classical and Insertion Alleles ( 0 )
      For All Classical and Insertion Alleles Show
       
      Other relevant insertions
      Transgenic Constructs ( 0 )
      For All Alleles Carried on Transgenic Constructs Show
      Transgenic constructs containing/affecting coding region of mt:tRNA:Glu-TTC
      Transgenic constructs containing regulatory region of mt:tRNA:Glu-TTC
      Aberrations (Deficiencies and Duplications) ( 0 )
      Inferred from experimentation
      Inferred from location
        Phenotypes
        For more details about a specific phenotype click on the relevant allele symbol.
        Phenotype manifest in
        Allele
        Orthologs
        Downloads
        Download All DIOPT Orthologs
        Download All OrthoDB Orthologs
        Human Orthologs (via DIOPT v8.0)
        Homo sapiens (Human) (0)
        No records found.
        Model Organism Orthologs (via DIOPT v8.0)
        Mus musculus (laboratory mouse) (0)
        No records found.
        Rattus norvegicus (Norway rat) (0)
        No records found.
        Xenopus tropicalis (Western clawed frog) (0)
        No records found.
        Danio rerio (Zebrafish) (0)
        No records found.
        Caenorhabditis elegans (Nematode, roundworm) (0)
        No records found.
        Arabidopsis thaliana (thale-cress) (0)
        No records found.
        Saccharomyces cerevisiae (Brewer's yeast) (0)
        No records found.
        Schizosaccharomyces pombe (Fission yeast) (0)
        No records found.
        Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( None identified )
        No orthologies identified
        Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( None identified )
        No non-Drosophilid orthologies identified
        Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( None identified )
        No non-Dipteran orthologies identified
        Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )
        No non-Insect Arthropod orthologies identified
        Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
        No non-Arthropod Metazoa orthologies identified
        Paralogs
        Downloads
        Download All DIOPT Paralogs
        Paralogs (via DIOPT v8.0)
        Drosophila melanogaster (Fruit fly) (0)
        No records found.
        Human Disease Associations
        FlyBase Human Disease Model Reports
          Disease Model Summary Ribbon
          Disease Ontology (DO) Annotations
          Models Based on Experimental Evidence ( 0 )
          Allele
          Disease
          Evidence
          References
          Potential Models Based on Orthology ( 0 )
          Human Ortholog
          Disease
          Evidence
          References
          Modifiers Based on Experimental Evidence ( 0 )
          Allele
          Disease
          Interaction
          References
          Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
          Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
          Homo sapiens (Human)
          Gene name
          Score
          OMIM
          OMIM Phenotype
          DO term
          Complementation?
          Transgene?
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          esyN Network Diagram
          Interactions Browser
          Summary of Genetic Interactions
          esyN Network Diagram
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          External Data
          Linkouts
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          External Data
          Linkouts
          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          mitochondrion_genome
          Recombination map
          Cytogenetic map
          Sequence location
          mitochondrion_genome:6,259..6,325 [+]
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (0)
          Genomic Clones (0)
           
            cDNA Clones (0)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequenced
            BDGP DGC clones
              Other clones
                Drosophila Genomics Resource Center cDNA clones

                For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                  cDNA Clones, End Sequenced (ESTs)
                  BDGP DGC clones
                    Other clones
                      RNAi and Array Information
                      Linkouts
                      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                      Antibody Information
                      Laboratory Generated Antibodies
                       
                      Commercially Available Antibodies
                       
                      Other Information
                      Relationship to Other Genes
                      Source for database identify of

                      Source for identity of: mt:tRNA:Glu-TTC mt:tRNA:E

                      (Marygold, 2016.3.15)
                      Source for database merge of
                      Additional comments
                      Other Comments

                      Amino acid: Glu. Anticodon: TTC.

                      (Jühling et al., 2009)

                      New annotation (CR34081) in release 4.3 of the genome annotation.

                      (FlyBase Genome Annotators, 2005)
                      Origin and Etymology
                      Discoverer
                      Etymology
                      Identification
                      External Crossreferences and Linkouts ( 13 )
                      Sequence Crossreferences
                      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                      RNAcentral - A comprehensive ncRNA sequence collection representing all ncRNA types from a broad range of organisms
                      Other crossreferences
                      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                      KEGG Genes - Molecular building blocks of life in the genomic space.
                      modMine - A data warehouse for the modENCODE project
                      Linkouts
                      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                      FlyMine - An integrated database for Drosophila genomics
                      KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                      Synonyms and Secondary IDs (10)
                      Reported As
                      Symbol Synonym
                      CR34081
                      (Göktaş et al., 2017, FlyBase Genome Annotators, 2005)
                      mt:tRNA:E
                      mt:tRNA:Glu-TTC
                      (Molla-Herman et al., 2020, Marygold, 2016.3.15)
                      mtdbD00006306
                      (Jühling et al., 2009)
                      tRNA Glu
                      (Azou and Bregliano, 2001)
                      tRNA-Glu-TTC
                      (Vaught et al., 2020)
                      tRNA-glu
                      (Chen et al., 2012)
                      tRNAGlu
                      (Roberti et al., 2003)
                      Name Synonyms
                      mitochondrial glutamic acid tRNA
                      mitochondrial transfer RNA:Glutamic acid-TTC
                      Secondary FlyBase IDs
                      • FBgn0002867
                      Datasets (0)
                      Study focus (0)
                      Experimental Role
                      Project
                      Project Type
                      Title
                      References (15)