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Gene Dmel\nuf

General Information
Symbol	Dmel\nuf	Species	D. melanogaster
Name	nuclear fallout	Annotation symbol	CG33991
Feature type	protein_coding_gene	FlyBase ID	FBgn0013718
Gene Model Status	Current	Stock availability	28 publicly available
Also Known As	D2, CG7867
Genomic Location
Chromosome (arm)	3L	Recombination map	3-
Cytogenetic map	70D3-70D4	Sequence location	3L:14,183,973..14,226,350 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene nuclear fallout is referred to in FlyBase by the symbol Dmel\nuf (CG33991, FBgn0013718). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: microtubule binding. There is experimental evidence that it is involved in the biological process: sensory organ precursor cell fate determination; wing disc dorsal/ventral pattern formation; actin cytoskeleton reorganization. 38 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; macrochaeta; intersegmental nerve; scutellar bristle. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: Rab-binding domain FIP-RBD. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression in all larval and adult organs/tissues ranges from low to undetected. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult hindgut, adult heart, larval fat body, adult salivary gland, larval trachea, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval/adult Malpighian tubules, adult fat body, larval salivary gland, adult female reproductive system, adult male reproductive system. Gene sequence location is 3L:14183973..14226350.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	References Reis et al., 2010, PLoS Genet. 6(11): e1001206 Carreira et al., 2011, BMC Dev. Biol. 11: 32 Sequence features BKN26020 HFA11379 BKN60353 BKN28267 BKN60622
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 70D3-70D4   Limits computationally determined from genome sequence between P{PZ}l(3)70Da02402&P{PZ}btl00208 and P{PZ}Mpcp00564
Experimentally Determined Cytological Location
Cytogenetic map Notes References 70D3-70D3   (determined by in situ hybridisation)   (Abdelilah-Seyfried et al., 2000) 70D3-70D3     (Rothwell, 1998.1.27) 70D3-70D3     (Rothwell et al., 1996) 70-70   (determined by in situ hybridisation)   (Sullivan et al., 1993)
Experimentally Determined Recombination Data
Location	3- (Rothwell et al., 1996)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\nuf for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene merge based on EST/cDNA data.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) nuf-RA FBtr0100040  NM_001038922   2696   502 nuf-RB FBtr0100042  NM_001038918   2373   305 nuf-RC FBtr0100039  NM_001038920   3446   502 nuf-RD FBtr0100041  NM_001038921   2446   316 nuf-RE FBtr0100043  NM_001038919   3230   528 nuf-RF FBtr0100044  NM_001038917   3097   528 nuf-RG FBtr0306619     3530   530 nuf-RH FBtr0306620     3527   529 nuf-RJ FBtr0306622     3269   541 nuf-RK FBtr0306623     3136   541 nuf-RL FBtr0306624     2735   515 nuf-RM FBtr0307191     2412   318
Additional Transcript Data & Comments
Reported size (kB)	3.5, 2.4 (northern blot) (Rothwell et al., 1998)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein nuf-PA   FBpp0075474   57.1   502   4.76     NP_001034011   AAF49749 nuf-PB   FBpp0075476   36.1   305   4.64     NP_001034007   AAN11807 nuf-PC   FBpp0075475   57.1   502   4.76     NP_001034009   ABC66147 nuf-PD   FBpp0089174   37.3   316   4.72     NP_001034010   AAS65011 nuf-PE   FBpp0100130   59.9   528   4.53     NP_001034008   ABC66148 nuf-PF   FBpp0100129   59.9   528   4.53     NP_001034006   ABC66149 nuf-PG   FBpp0297574   60.2   530   4.80       nuf-PH   FBpp0297575   60.1   529   4.80       nuf-PJ   FBpp0297577   61.1   541   4.49       nuf-PK   FBpp0297578   61.1   541   4.49       nuf-PL   FBpp0297579   58.3   515   4.70       nuf-PM   FBpp0298020   37.4   318   4.57
Additional Polypeptide Data & Comments
Reported size (kDa)	502 (aa); 57 (kD predicted) (Rothwell et al., 1998)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Rab-binding domain FIP-RBD (IPR019018)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202853   AA246855   AA265007   AA392697   AA439063   AA440281   AA441297   AA538697   AA696238   AA816721   AA950972   AE014296 AAF49749   AE014296 AAN11807   AE014296 AAS65011   AE014296 ABC66147   AE014296 ABC66148   AE014296 ABC66149   AF045015 AAC05669   AI518604   AI947146   AQ025259   AQ073913   AQ073928   AW941684   AY060923   AY069380 AAL39525   AY071395 AAL49017   BG638863   BH615061   BH854678   BH901050   BI165356   BI167305   BI172807   BI212223   BI216840   BI229868   BI231243   BI231917   BI232094   BI234304   BI236826   BI240119   BI240881   BI242487   BI243907   BI353100   BI356090   BI356932   BI356987   BI357348   BI361693   BI362320   BI363958   BI365514   BI366100   BI367708   BI367800   BI369031   BI370713   BI371888   BI374110   BI374586   BI605202   BI614494   BI616351   BT011468   BT044478   BT100278   BT120185   BT120193   BT125946   BZ286218   CA807120   CK131604   CK131973   CK135436   CK135616   CL528040   CO179498   CO189675   CO189895   CO190830   CO191770   CO267171   CO268711   CO268764   CO268886   CO269418   CO275235   CO275245   CO275600   CO276789   CO278045   CO283736   CO284567   CO284620   CO285683   CO287432   CO294587   CO301036   CO303015   CO304563   CO306486   CO308235   CO310017   CO310326   CO310753   CO312669   CO315899   CO317198   CO326660   CO326827   CO327081   CO330954   CO331341   CO331374   CO335431   CO342703   CZ469263   CZ469264   CZ475858   CZ478098   CZ478099   CZ479139   CZ481287   CZ481324   CZ485070   EC051698   EC057620   EC057931   EC059907   EC062064   EC062080   EC064246   EC064594   EC064729   EC067044   EC067556   EC069045   EC071124   EC076797   EC078527   EC082676   EC084034   EC087514   EC087923   EC088310   EC088553   EC195453   EC197169   EC197803   EC200545   EC206890   EC207030   EC209524   EC211485   EC215004   EC215439   EC220119   EC220512   EC221842   EC224384   EC226791   EC238314   EC240344   EC241857   EC243888   EC244267   EC245874   EC246158   EC250942   EC250950   EC252357   EC256085   EC256558   EC259563   EC260146   EC262219   EL873748   EL873853   ES693781   ES694513   ES694916   ES695198   EV582100   EV599745   GH944056   GH946390   GH947351   GH949062   GH952372   GH959391   GH962012   GH967134   GH967724   GH972970   GH973284   GH977506   GH982677   GH983433   GH984254   GH984843
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O61495 Q7KUK1 Q8SYQ0 Q8T0E0 Q9VUD7 Q6NN29
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 6     (Rothwell et al., 1998) Comment:reference states 0-3 hr AEL
Additional Descriptive Data
	nuf transcripts are detected in 0-3 hr embryos. (Rothwell et al., 1998)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
western blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 6     (Rothwell et al., 1998) Comment:reference states 0-3 hr AEL embryonic stage 4     (Rothwell et al., 1998) embryonic stage 5     (Rothwell et al., 1998)
Additional Descriptive Data
	A major band of 95 kD and minor bands of 82 and 67 kD are detected in Western blots of 0-3 hr embryos. Following phosphatase treatment, only a single 67 kD band is observed. During late syncytial divisions, nuf protein is highly concentrated at the centrosomes during prophase, and is cytoplasmic during other stages of the nuclear cycle. nuf protein is also concentrated at the centrosomes during interphase of nuclear cycle 14, and during cellularization. (Rothwell et al., 1998)
Marker for
Subcellular Localization
CV Term	centrosome, cytoplasm (Rothwell et al., 1998)
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0013718    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0013718 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0013718 expression level Developmental Stage   Expression Level embryo 00-02hr    2833 embryo 02-04hr    2541 embryo 04-06hr    1986 embryo 06-08hr    2470 embryo 08-10hr    2549 embryo 10-12hr    2518 embryo 12-14hr    3080 embryo 14-16hr    2814 embryo 16-18hr    3109 embryo 18-20hr    2725 embryo 20-22hr    2551 embryo 22-24hr    2887 larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9    1752 white prepupae new    2039 white prepupae 12hr    2098 white prepupae 24hr    1783 pupae 2d postWPP    3231 pupae 3d postWPP    1634 pupae 4d postWPP    1364 adult male 01day    1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day    1995 adult female 30day    1829 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2833) embryo 02-04hr  (2541) embryo 04-06hr  (1986) embryo 06-08hr  (2470) embryo 08-10hr  (2549) embryo 10-12hr  (2518) embryo 12-14hr  (3080) embryo 14-16hr  (2814) embryo 16-18hr  (3109) embryo 18-20hr  (2725) embryo 20-22hr  (2551) embryo 22-24hr  (2887) larva L1  (689) larva L2  (860) larva L3 12hr old  (639) larva L3 puffstage 1-2  (525) larva L3 puffstage 3-6  (1090) larva L3 puffstage 7-9  (1752) white prepupae new  (2039) white prepupae 12hr  (2098) white prepupae 24hr  (1783) pupae 2d postWPP  (3231) pupae 3d postWPP  (1634) pupae 4d postWPP  (1364) adult male 01day  (1506) adult male 05day  (1285) adult male 30day  (1029) adult female 01day  (1382) adult female 05day  (1995) adult female 30day  (1829) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2833) embryo 02-04hr  (2541) embryo 04-06hr  (1986) embryo 06-08hr  (2470) embryo 08-10hr  (2549) embryo 10-12hr  (2518) embryo 12-14hr  (3080) embryo 14-16hr  (2814) embryo 16-18hr  (3109) embryo 18-20hr  (2725) embryo 20-22hr  (2551) embryo 22-24hr  (2887) larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9  (1752) white prepupae new  (2039) white prepupae 12hr  (2098) white prepupae 24hr  (1783) pupae 2d postWPP  (3231) pupae 3d postWPP  (1634) pupae 4d postWPP    1364 adult male 01day  1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day  (1995) adult female 30day  (1829) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2833 embryo 02-04hr    2541 embryo 04-06hr    1986 embryo 06-08hr    2470 embryo 08-10hr    2549 embryo 10-12hr    2518 embryo 12-14hr    3080 embryo 14-16hr    2814 embryo 16-18hr    3109 embryo 18-20hr    2725 embryo 20-22hr    2551 embryo 22-24hr    2887 larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9    1752 white prepupae new    2039 white prepupae 12hr    2098 white prepupae 24hr    1783 pupae 2d postWPP    3231 pupae 3d postWPP    1634 pupae 4d postWPP    1364 adult male 01day    1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day    1995 adult female 30day    1829 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2833 embryo 02-04hr    2541 embryo 04-06hr    1986 embryo 06-08hr    2470 embryo 08-10hr    2549 embryo 10-12hr    2518 embryo 12-14hr    3080 embryo 14-16hr    2814 embryo 16-18hr    3109 embryo 18-20hr    2725 embryo 20-22hr    2551 embryo 22-24hr    2887 larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9    1752 white prepupae new    2039 white prepupae 12hr    2098 white prepupae 24hr    1783 pupae 2d postWPP    3231 pupae 3d postWPP    1634 pupae 4d postWPP    1364 adult male 01day    1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day    1995 adult female 30day    1829 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0013718 expression level Developmental Stage   Expression Level embryo 00-02hr    2833 embryo 02-04hr    2541 embryo 04-06hr    1986 embryo 06-08hr    2470 embryo 08-10hr    2549 embryo 10-12hr    2518 embryo 12-14hr    3080 embryo 14-16hr    2814 embryo 16-18hr    3109 embryo 18-20hr    2725 embryo 20-22hr    2551 embryo 22-24hr    2887 larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9    1752 white prepupae new    2039 white prepupae 12hr    2098 white prepupae 24hr    1783 pupae 2d postWPP    3231 pupae 3d postWPP    1634 pupae 4d postWPP    1364 adult male 01day    1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day    1995 adult female 30day    1829 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2833) embryo 02-04hr  (2541) embryo 04-06hr  (1986) embryo 06-08hr  (2470) embryo 08-10hr  (2549) embryo 10-12hr  (2518) embryo 12-14hr  (3080) embryo 14-16hr  (2814) embryo 16-18hr  (3109) embryo 18-20hr  (2725) embryo 20-22hr  (2551) embryo 22-24hr  (2887) larva L1  (689) larva L2  (860) larva L3 12hr old  (639) larva L3 puffstage 1-2  (525) larva L3 puffstage 3-6  (1090) larva L3 puffstage 7-9  (1752) white prepupae new  (2039) white prepupae 12hr  (2098) white prepupae 24hr  (1783) pupae 2d postWPP  (3231) pupae 3d postWPP  (1634) pupae 4d postWPP  (1364) adult male 01day  (1506) adult male 05day  (1285) adult male 30day  (1029) adult female 01day  (1382) adult female 05day  (1995) adult female 30day  (1829) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2833) embryo 02-04hr  (2541) embryo 04-06hr  1986 embryo 06-08hr  2470 embryo 08-10hr  (2549) embryo 10-12hr  (2518) embryo 12-14hr  (3080) embryo 14-16hr  (2814) embryo 16-18hr  (3109) embryo 18-20hr  (2725) embryo 20-22hr  (2551) embryo 22-24hr  (2887) larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9  1752 white prepupae new  2039 white prepupae 12hr  2098 white prepupae 24hr  1783 pupae 2d postWPP  (3231) pupae 3d postWPP  1634 pupae 4d postWPP    1364 adult male 01day  1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day  1995 adult female 30day  1829 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2833 embryo 02-04hr    2541 embryo 04-06hr    1986 embryo 06-08hr    2470 embryo 08-10hr    2549 embryo 10-12hr    2518 embryo 12-14hr    3080 embryo 14-16hr    2814 embryo 16-18hr    3109 embryo 18-20hr    2725 embryo 20-22hr    2551 embryo 22-24hr    2887 larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9    1752 white prepupae new    2039 white prepupae 12hr    2098 white prepupae 24hr    1783 pupae 2d postWPP    3231 pupae 3d postWPP    1634 pupae 4d postWPP    1364 adult male 01day    1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day    1995 adult female 30day    1829 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2833 embryo 02-04hr    2541 embryo 04-06hr    1986 embryo 06-08hr    2470 embryo 08-10hr    2549 embryo 10-12hr    2518 embryo 12-14hr    3080 embryo 14-16hr    2814 embryo 16-18hr    3109 embryo 18-20hr    2725 embryo 20-22hr    2551 embryo 22-24hr    2887 larva L1    689 larva L2    860 larva L3 12hr old    639 larva L3 puffstage 1-2    525 larva L3 puffstage 3-6    1090 larva L3 puffstage 7-9    1752 white prepupae new    2039 white prepupae 12hr    2098 white prepupae 24hr    1783 pupae 2d postWPP    3231 pupae 3d postWPP    1634 pupae 4d postWPP    1364 adult male 01day    1506 adult male 05day    1285 adult male 30day    1029 adult female 01day    1382 adult female 05day    1995 adult female 30day    1829 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0013718    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0013718 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression in all larval and adult organs/tissues ranges from low to undetected. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult hindgut, adult heart, larval fat body, adult salivary gland, larval trachea, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval/adult Malpighian tubules, adult fat body, larval salivary gland, adult female reproductive system, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_27
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0013718 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7867-RA;CG32140-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for nuf Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage | maternal effect nuf1 lethal | embryonic stage | maternal effect (with nuf1) nufCy3-23 lethal | embryonic stage | maternal effect (with nufCy3-23) nuf1 lethal | maternal effect | recessive nuf1 nuf2 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 nufGD10800 viable nufe03568 nufEY07564 viable, with Scer\GAL4pnr-MD237 nufGD12309 Sterility Allele fertile nufe03568 nufEY07564 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL4elav-C155 nufEP3077 visible, with Scer\GAL4sca-537.4 nufEP3324 nufEP3339 wild-type nufGerm.10 Phenotype manifest in Allele actin cytoskeleton | embryonic stage nuf1 anterior fascicle & synapse, with Scer\GAL4elav-C155 nufEP3077 anterior fascicle & synapse | supernumerary, with Scer\GAL4elav-C155 nufEP3077 cycle 11 embryo | maternal effect nuf1 cycle 12 embryo | maternal effect nuf1 cycle 13 embryo | maternal effect nuf1 cycle 14 embryo | maternal effect nuf1 intersegmental nerve, with Scer\GAL4elav-C155 nufEP3077 macrochaeta nufBG02180 mitotic telophase | maternal effect nuf1 nucleus | embryonic stage nuf1 scutellar bristle, with Scer\GAL4sca-537.4 nufEP3339 scutellar bristle | ectopic, with Scer\GAL4sca-537.4 nufEP3324 nufEP3339 socket | supernumerary, with Scer\GAL4sca-109-68 nufEP3324 trichogen cell, with Scer\GAL4sca-109-68 nufEP3324 trichogen cell | ectopic, with Scer\GAL4sca-537.4 nufEP3324
Classical Alleles ( 29 )
For All Classical Alleles Show
Allele of nuf Class Mutagen Stocks Known lesion nufe03568 piggyBac transposase 2 -- nufKG02305 P-element activity 2 -- nuf5-SZ-3064 1 -- nufc04452 piggyBac transposase 1 -- nufCB-5139-3 1 -- nufCB-6699-3 1 -- nufd07661 P-element activity 1 -- nufDG10303 1 -- nufe00217 piggyBac transposase 1 -- nufe01327 piggyBac transposase 1 -- nufe03521 piggyBac transposase 1 -- nufEY07564 P-element activity 1 -- nuff02544 piggyBac transposase 1 -- nuff06781 1 -- nufGS9035 1 Yes nufKG00314 P-element activity 1 -- nufKG07646 P-element activity 1 -- nufKG08606 P-element activity 1 -- nufMB09772 1 -- nuf1 loss of function allele P-element activity 0 -- nuf2 loss of function allele P-element activity 0 -- nuf5-HA-1991 0 -- nufBG02180 P-element activity 0 Yes nufCy3-23 P-element activity 0 Yes nufEP3-1715 0 -- nufEP3077 P-element activity 0 Yes nufEP3324 P-element activity 0 Yes nufEP3339 P-element activity 0 Yes nufunspecified 0 --
Alleles Carried on Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Allele of nuf Class Mutagen Stocks Known lesion nufGD10800 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes nufGD12309 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes nufJF01350 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes nufJF01351 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes nufJF02728 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes nufKK106020 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes nufGerm.10 in vitro construct - regulatory fusion 0 Yes nufKK108267 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes nufT:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)BSC801 (Christensen et al., 2009.5.6) Df(3L)D5 (Carpenter, 2001.3.12, Peterson and Petri, 1995) Df(3L)Exel6121 (Ryder, 2004.4.26)
Duplicated in	Dp(3;4)D4rv42 (Peterson and Petri, 1995)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10800} NA P{GD12309} NA P{KK106020} NA P{KK108267} NA P{TRiP.JF01350} NA P{TRiP.JF01351} NA P{TRiP.JF02728} NA characterization construct P{Germ10-nuf} NA P{GFP-nuf} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}nufEP3-1715 NA P{EP}nufEP3077 NA P{EP}nufEP3324 NA P{EP}nufEP3339 NA P{EPgy2}nufEY07564 NA P{GSV6}nufGS9035 NA P{XP}nufd07661 NA miscellaneous insertions P{}nuf1 NA P{}nuf2 NA P{GT1}nufBG02180 NA P{RS3}nufCB-5139-3 NA P{RS3}nufCB-6699-3 NA P{RS5}nuf5-HA-1991 NA P{RS5}nuf5-SZ-3064 NA P{SUPor-P}nufKG00314 NA P{SUPor-P}nufKG02305 NA P{SUPor-P}nufKG07646 NA P{SUPor-P}nufKG08606 NA P{wHy}nufDG10303 NA PBac{PB}nufc04452 NA PBac{RB}nufe00217 NA PBac{RB}nufe01327 NA PBac{RB}nufe03521 NA PBac{RB}nufe03568 NA PBac{WH}nuff02544 NA PBac{WH}nuff06781 NA insertion of enhancer trap P{lacZ-un3}nufCy3-23 No insertion of enhancer trap binary system Mi{ET1}nufMB09772 No
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
actin cytoskeleton reorganization inferred from mutant phenotype (Riggs et al., 2003) sensory organ precursor cell fate determination inferred from mutant phenotype (Emery et al., 2005) wing disc dorsal/ventral pattern formation inferred from genetic interaction with Bx, ap (Bejarano et al., 2008)
Cellular Component
CV term Evidence References
colocalizes_with centrosome inferred from direct assay (Emery et al., 2005) perinuclear region of cytoplasm inferred from direct assay (Giansanti et al., 2007)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
microtubule binding inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000)
Biological Process
CV term Evidence References
cytokinesis, actomyosin contractile ring assembly non-traceable author statement (Tepass et al., 2001) microtubule-based process inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000)
Cellular Component
CV term Evidence References
centrosome traceable author statement (Tepass et al., 2001) microtubule associated complex inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions nuf allele Gene References unspecified D1 (Sun et al., 2006) H (Mueller et al., 2005) l(2)gl (Emery et al., 2005) lap (Sun et al., 2006) pbl (Gregory et al., 2007) Rab11 (Emery et al., 2005) rpr (Mueller et al., 2005) W (Mueller et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 64907 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0013718 DroID - A comprehensive database of gene and protein interactions. • FBgn0013718 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39572
Orthologs
Genome-wide drosophilid orthologs	Dana\GF24596 Dgri\GH17096 Dmoj\GI11698 Dpse\GA23801 Dvir\GJ11373 Dwil\GK12678
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL006776-PA Aedes aegypti (mosquito) AGAP010445-PA Anopheles gambiae (mosquito) XP_392795.2 Apis mellifera (honey bee) XP_001952580.1 Acyrthosiphon pisum (pea aphid) 68696 Branchiostoma floridae (lancelet) BGIBMGA011840-PA Bombyx mori (silk worm) ENSBTAP00000022068 Bos taurus (bovine) CN20301 Caenorhabditis brenneri (small nematode) CE28452 Caenorhabditis elegans (worm) ENSCAFP00000027341 Canis familiaris (dog) JA03517 Caenorhabditis japonica (nematode) CPIJ015278 Culex pipens (mosquito) ENSCPOP00000010464 Cavia porcellus (guinea pig) RP48787 Caenorhabditis remanei (nematode) 55126 Daphnia pulex (daphnia) ENSDARP00000070439 Danio rerio (zebra fish) ENSDARP00000088256 Danio rerio (zebra fish) ENSDARP00000093851 Danio rerio (zebra fish) ENSECAP00000004679 Equus caballus (horse) ENSGACP00000011186 Gymnopilus aculeatus (mushroom) ENSGACP00000025702 Gymnopilus aculeatus (mushroom) ENSGALP00000005100 Gallus gallus (chicken) ENSP00000378227 Homo sapiens (human) ENSMMUP00000000825 Macaca mulatta (rhesus monkey) ENSMUSP00000017783 Mus musculus (house mouse) XP_001602915.1 Nasonia vitripennis (wasp) ENSOANP00000016338 Ornithorynchus anatinus (platypus) ENSORLP00000009382 Oryzias latipes (japanese killifish) PP01878 Pristionchus pacificus (nematode) ENSPPYP00000009164 Pongo pygmaeus (orangutan) ENSPTRP00000015317 Pan troglodytes (chimpanzee) ENSRNOP00000018988 Rattus norvegicus (norway rat) XP_784561.2 Strongylocentrotus purpuratus (purple sea urchin) 60532 Trichoplax adhaerens (metazoa) XP_975062.2 Tribolium castaneum (red flour beetle) ENSTNIP00000005818 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000030175 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000022729 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV16753 LH18492 ISCW016229 FBgn0239241 FBgn0214687 FBgn0198632 FBgn0186168 FBgn0180318 JGI_V11_55126 FBgn0245200 FBgn0134457 FBgn0124566 FBgn0107923 FBgn0101589 CPIJ015278 BGIBMGA011840 ACYPI44946 ACYPI007157 GB19309 AGAP010445 AAEL006776 PB24155 GLEAN_03516
Stocks & Reagents
Stocks Listed in FlyBase ( 28 )
Harvard	- P{XP}nufd07661 - PBac{PB}nufc04452 - PBac{RB}nufe00217 - PBac{RB}nufe01327 - PBac{RB}nufe03521 - PBac{RB}nufe03568 - PBac{WH}nuff02544 - PBac{WH}nuff06781
VDRC	v104172 P{KK106020}VIE-260B v34416 w1118 P{GD10800}v34416 v28069 w1118; P{GD12309}v28069 v34417 w1118; P{GD10800}v34417
	More stocks available...
Genomic Clones ( 2 )
	BACR02M13 BACR16J19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 168 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM06533 LD08622 RE24122 RE37018 RE46851 RH57811
Other clones	DPiM_GM06533 DPiM_RE46851 MIP15941 MIP16041 RH09135
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM05354 GM22214 LD03447 LD04858 LD05880 LD11493 LD13509 LD15208 LD16180 LD18283 LD31167 LP12505 LP13108 RE05233 RE07657 RE15486 RE17271 RE20481 RE24892 RE27741 RE28108 RE29986 RE32947 RE36768 RE37831 RE39835 RE41724 RE42133 RE43233 RE43319 RE43810 RE46024 RE48956 RE50856 RE51554 RE53515 RE53645 RE55112 RE57440 RE58910 RE61629 RE62220 RH43868 RH57810 RH70748
Other clones	489 5772 11543 14431 16972 30127 34350 44481 44671 54840 57017 58712 62122 75161 80245 97557 98289 100056 104914 117375 121132 153298 157368 159887 163062 175677 193772 214309.21 214409.56 214413.48 214471.51 214541.39 272573 272721 533868 bs35f03 CK01.16C.B10 CK01.32B.H11 CK01.35C.E7 CK01.55C.G2 CK01.56B.G7 CK01.56C.E3 CK01.62A.F12 CK01.76B.B10 CK01.121A.G3 CK01.121C.G6 CK01.124A.E10 CK01.127B.F7 CK01.141D.F3 Dmel_dig_015262_0648_1917 Dmel_neb_015744_0908_1097 EC31788 EK044857 EK045528 EK049856 EK059539 EK065836 EK092502 EK092626 EK092959 EK094449 EK116835 EK116909 EK118022 EK122053 EK128611 EK148948 EK164216 EK166319 EK166426 EK169849 EK179935 EK185352 EK207241 EK220248 EK221232 EK222434 EK229624 EK245120 EK251201 EK257051 EK262949 EK267319 EK296654 EK299321 EK299430 EN10322 EP04412 EP04718 EP05726 EP15352 ESG016b.E21_E08 IP13839 IP13939 LD38215 RH46274 RP004145112 RP004190002 RP004200142 RP004209888 RP004210043 RP004218277 RP004220312 RP004245879 RP004289469 RP004384302 RP004388887 RP004463700 RP004470884 RP004530118 RP004551287 RP004559858
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0013718 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39572 317879
Antibody Information
	polyclonal (Rothwell et al., 1998, Otani et al., 2011)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: nuf CG7867 (Bayraktaroglu, 1999.11)
Source for database merge of	Source for merge of: nuf CIP-D2 anon-D2 (Perkins, 2001.9.13) Source for merge of: nuf EP3077 (FlyBase Genome Annotators, 2005, FlyBase, 1996-)
Additional comments	Source for merge of nuf EP3077 was location of EP3077 insertion (date:020218). (FlyBase Genome Annotators, 2005, FlyBase, 1996-)
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) New annotation (CG32140) in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) The nuf-mutant phenotype is used to investigate the process by which a furrow is constructed. (Rothwell et al., 1998) Protein interacts specifically with csw unique catalytic insert domain. (Johnson et al., 1997) Identification: Yeast two hybrid screen for proteins that interact with the csw protein's protein phosphatase domain. (Denhez et al., 1996) nuf gene product has a zinc finger motif. (Peterson and Petri, 1995) Deficiency analysis localized nuf to 70D2-70D6. (Sullivan et al., 1993) Defined in a screen of maternal-effect lethal mutations that cause defects in nuclear movement, organization or morphology during the syncytial embryonic divisions. (Sullivan et al., 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001038917 NM_001038918 NM_001038919 NM_001038920 NM_001038921 NM_001038922 RefSeq (Proteins) • NP_001034006 NP_001034007 NP_001034008 NP_001034009 NP_001034010 NP_001034011 DDBJ / EMBL / GenBank • AA265007 AAC05669 AAF49749 AAF49749.1 AAL39525 AAL49017 AAN11804.1 AAN11807 AAN11807.1 AAN11808.1 AAN11809.1 AAS65011 AAS65011.1 ABC66147 ABC66148 ABC66149 AF045015 AQ025259 AQ073913 AQ073928 AW941684 AY069380 AY071395 BH615061 BH854678 BH901050 BI216840 BI362320 BZ286218 CL528040 CZ469263 CZ469264 CZ475858 CZ478098 CZ478099 CZ479139 CZ481287 CZ481324 CZ485070 Entrez Gene - A searchable database of RefSeq genes. • 39572 UniProtKB/TrEMBL • O61495 Q6NN29 Q7KUK1 Q8SYQ0 Q8T0E0 Q9VUD7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Rab-binding domain FIP-RBD (IPR019018)
Linkouts
	BioGRID - A database of protein and genetic interactions • 64907 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0013718 DroID - A comprehensive database of gene and protein interactions. • FBgn0013718 DRSC - Results from RNAi screens. • FBgn0013718 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0013718 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7867-RA;CG32140-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0013718 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39572 317879 InParanoid A subset of ortholog calls from InParanoid. • AAEL006776-PA Aedes aegypti (mosquito) AGAP010445-PA Anopheles gambiae (mosquito) XP_392795.2 Apis mellifera (honey bee) XP_001952580.1 Acyrthosiphon pisum (pea aphid) 68696 Branchiostoma floridae (lancelet) BGIBMGA011840-PA Bombyx mori (silk worm) ENSBTAP00000022068 Bos taurus (bovine) CN20301 Caenorhabditis brenneri (small nematode) CE28452 Caenorhabditis elegans (worm) ENSCAFP00000027341 Canis familiaris (dog) JA03517 Caenorhabditis japonica (nematode) CPIJ015278 Culex pipens (mosquito) ENSCPOP00000010464 Cavia porcellus (guinea pig) RP48787 Caenorhabditis remanei (nematode) 55126 Daphnia pulex (daphnia) ENSDARP00000070439 Danio rerio (zebra fish) ENSDARP00000088256 Danio rerio (zebra fish) ENSDARP00000093851 Danio rerio (zebra fish) ENSECAP00000004679 Equus caballus (horse) ENSGACP00000011186 Gymnopilus aculeatus (mushroom) ENSGACP00000025702 Gymnopilus aculeatus (mushroom) ENSGALP00000005100 Gallus gallus (chicken) ENSP00000378227 Homo sapiens (human) ENSMMUP00000000825 Macaca mulatta (rhesus monkey) ENSMUSP00000017783 Mus musculus (house mouse) XP_001602915.1 Nasonia vitripennis (wasp) ENSOANP00000016338 Ornithorynchus anatinus (platypus) ENSORLP00000009382 Oryzias latipes (japanese killifish) PP01878 Pristionchus pacificus (nematode) ENSPPYP00000009164 Pongo pygmaeus (orangutan) ENSPTRP00000015317 Pan troglodytes (chimpanzee) ENSRNOP00000018988 Rattus norvegicus (norway rat) XP_784561.2 Strongylocentrotus purpuratus (purple sea urchin) 60532 Trichoplax adhaerens (metazoa) XP_975062.2 Tribolium castaneum (red flour beetle) ENSTNIP00000005818 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000030175 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000022729 Xenopus tropicalis (frog) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /sturtevant/nucfallout1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39572 modMine - Data generated by the modENCODE project. • FBgn0013718 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV16753 LH18492 ISCW016229 FBgn0239241 FBgn0214687 FBgn0198632 FBgn0186168 FBgn0180318 JGI_V11_55126 FBgn0245200 FBgn0134457 FBgn0124566 FBgn0107923 FBgn0101589 CPIJ015278 BGIBMGA011840 ACYPI44946 ACYPI007157 GB19309 AGAP010445 AAEL006776 PB24155 GLEAN_03516
Synonyms & Secondary IDs ( 20 )
Reported As
Symbol Synonym	anon-D2 (Perkins, 2001.9.13) CG7867 (Norga et al., 2003, Goldstein and Gunawardena, 2000, ) CG32140 (Giot et al., 2003, ) CG33991 (FlyBase Genome Annotators, 2005, Keleman et al., 2009.8.5, Perkins et al., 2009, Ni et al., 2008) CIP-D2 (Perkins, 2001.9.13) Cy3-23 (Peterson and Petri, 1995, ) D2 (Johnson et al., 1997, Denhez et al., 1996, Lorenzen et al., 1998) EP3077   FIP3 (van IJzendoorn, 2006) nuf (Emery et al., 2005, Sandmann et al., 2007, Liebl et al., 2006, Bejarano et al., 2008, Christensen et al., 2009.5.6, Fang et al., 2009, Morozova et al., 2007, Wheeler et al., 2009, Karbowniczek et al., 2010, Hoskins et al., 2011, Hazelett et al., 2009, Reis et al., 2010) Nuf (Somers and Chia, 2005, Langevin et al., 2005, Sevrioukov et al., 2005, Crest and Sullivan, 2008, van IJzendoorn, 2006, Cao et al., 2008, Slack et al., 2007, Riggs et al., 2007, Giansanti et al., 2007, Shaye et al., 2008, McCleland and O'Farrell, 2008, Perkins, 2001.9.13, Polevoy et al., 2009, Kim et al., 2005, Sommi et al., 2010, Kao and Megraw, 2009) NUF (Lecuit, 2004) Nuf2p (White and Erickson, 2009) unnamed (Kraut et al., 2001)
Name Synonym	Corkscrew Interacting Protein-D2 (Perkins, 2001.9.13) nuclear-fallout (Scaria et al., 2004, Sullivan et al., 1993, Lecuit, 2004) nuclear fallout (Perkins, 2001.9.13, Gregory et al., 2007, Morozova et al., 2007, Morozova et al., 2006, Karbowniczek et al., 2010) Nuclear fallout (Polo and Di, 2006, van IJzendoorn, 2006, Cao et al., 2008, Slack et al., 2007) Nuclear Fallout (Thomas and Noselli, 2007) Nuclear-fallout (Riggs et al., 2007, McCleland and O'Farrell, 2008)
Secondary FlyBase IDs
	FBgn0013768 FBgn0015626 FBgn0024703 FBgn0044464 FBgn0052140 FBgn0053991 FBpp0075474 FBpp0075475 FBpp0075476 FBpp0075480 FBpp0075481 FBpp0089174 FBtr0075731 FBtr0075732 FBtr0075733 FBtr0075734 FBtr0075738 FBtr0075739
References ( 95 )
Generate a list of	All references relating to this gene ( 95 )
List References by type	Research paper  ( 40 ) Supplementary material  ( 7 ) Review  ( 14 ) Personal communication to FlyBase  ( 10 ) Abstract  ( 13 ) FlyBase analysis  ( 5 ) Curated genome annotation  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 6 )
	Carreira et al., 2011, BMC Dev. Biol. 11: 32 Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273] Hoskins et al., 2011, Genome Res. 21(2): 182--192 Genome-wide analysis of promoter architecture in Drosophila melanogaster. [FBrf0213090] Otani et al., 2011, Dev. Cell 20(2): 219--232 IKKɛ Regulates Cell Elongation through Recycling Endosome Shuttling. [FBrf0212985] Karbowniczek et al., 2010, J. clin. Invest. 120(1): 93--102 The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development. [FBrf0209596] Reis et al., 2010, PLoS Genet. 6(11): e1001206 A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for sir2 in coupling fat storage to nutrient availability. [FBrf0212335] Sommi et al., 2010, J. Cell Sci. 123(11): 1862--1872 A mitotic kinesin-6, Pav-KLP, mediates interdependent cortical reorganization and spindle dynamics in Drosophila embryos. [FBrf0210830] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...