P450
Please see the GBrowse view of Dmel\Cyp6a8 or the JBrowse view of Dmel\Cyp6a8 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
Gene model reviewed during 5.50
2.0, 1.8 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Cyp6a8 using the Feature Mapper tool.
Cyp6a8 transcripts are detected in adults. Strain differences are observed between DDT-resistant and sensitive strains. Transcript levels are increased following barbitol treatment.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Cyp6a8 in GBrowse 2
2-73
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Isolated from a cDNA library of the 91-R strain, using Cyp6a2 cDNA as a probe, under reduced stringency conditions.
A Cyp6a8 cDNA has been cloned and sequenced.
Isolated in a cDNA library under low stringency using Cyp6a2 cDNA as a probe.
The adenylate cyclase inactivator forskolin and its pharmacologically inactive derivative 1,9-dideoxyforskolin inhibit, in a dose-dependent fashion, the ecdysone 20-monooxygenase activity associated with wandering stage larvae.
