FK506-bp2, FK506-binding protein 2
Gene model reviewed during 5.44
Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Fkbp12 using the Feature Mapper tool.
In the synsytial embryo Fkbp12 mRNA is expressed in the cytoplasm. At cellular blastoderm it is located in the inner limits of the blastoderm cells and is higher in the anterior region of the embryo than at the posterior region. Later expression is mainly in the developing gut and in muscle.
Expression pattern inferred from unspecified enhancer trap line.
In the syncytial blastoderm embryo, Fkbp12 protein localizes mainly to the aneterior and posterior poles. In the cellular blastoderm, staining is mainly in the cortex. It is concentrated in the basal-cell layer zone and aggregated in the basement membrane. At germ band extension, Fkbp12 is mainly expressed in neuroblasts, stomodeum, and the developing gut. At later stages, expression is in the brain, supraesophageal ganglion, ventral nervous system, midgut, and posterior midgut rudiment. At late gastrulation, expression is continuously detected in the digestive, muscular, and nervous systems including the mouth hook. head muscle, pharyngeal musculature, brain supraesophageal ganglion, subesophageal ganglion, ventral nervous system, proventriculus, midgut, and salivary gland.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Fkbp12 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.