4f-rnp, rnp-4f
Please see the JBrowse view of Dmel\Rnp4F for information on other features
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Gene model reviewed during 5.50
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.55
3.127 (longest cDNA)
3.5, 3.2 (northern blot)
943, 639, 555 (aa); 124, 84, 70 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rnp4F using the Feature Mapper tool.
Comment: maternally deposited
The relative proportions of the long and short Rnp4F, which differ with respect to splicing of an untranslated upstream exon, change significiantly over the course of embryogenesis.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Rnp4F in GBrowse 2
1-11
1-11
1-13.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Rnp4F CG3312
RNAi knockdown shows that the long Rnp4F isoform is required for normal central nervous system (CNS) development and acts upstream of other genes that are important for CNS development.
RNA editing occurs in an alternatively spliced adult head transcript arising from the single-copy nuclear Rnp4F gene via numerous A to G conversions (as shown by comparison of genomic and cDNA nucleotide sequences).
