dSR-CI, Sr-Cl, dSR-C1, SR-C1
Gene model reviewed during 5.47
Gene model reviewed during 5.56
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sr-CI using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Sr-CI in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Identified in an RNAi screen for host factors that alter infection of SL2 cells by M.fortuitum.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identified as a gene with significant level of mRNA cycling as assessed by expression analysis using high density oligonucleotide arrays with probe generated from adult heads harvested over six time points over the course of a day. Shows alteration in expression in a Clk mutant background.
Sr-CI may participate in a variety of macrophage/hemocyte functions so could play a role in host defense, cell-cell or cell-matrix adhesion and wound healing.
Embryonic macrophages and the macrophage-like Schneider L2 cell line exhibit a scavenger receptor activity resembling that of the mammalian macrophage-specific SR-A.