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Gene Dmel\mof

General Information
Symbol	Dmel\mof	Species	D. melanogaster
Name	males absent on the first	Annotation symbol	CG3025
Feature type	protein_coding_gene	FlyBase ID	FBgn0014340
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	max, dMOF
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	5C5-5C5	Sequence location	X:5,767,868..5,770,884 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene males absent on the first is referred to in FlyBase by the symbol Dmel\mof (CG3025, FBgn0014340). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: chromatin binding. There is experimental evidence that it is involved in the biological process: dosage compensation. 36 alleles are reported. The phenotype of these alleles is annotated with: heart primordium. It has one annotated transcript and one annotated polypeptide. Protein features are: Acyl-CoA N-acyltransferase; Chromo domain-like; Chromo domain/shadow; MOZ/SAS-like protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1633429_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mof. Gene sequence location is X:5767868..5770884.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Schiemann et al., 2010, Biochem. Biophys. Res. Commun. 402(4): 699--704 Andersen et al., 2010, Mol. Cell. Biol. 30(19): 4744--4755 Sequence features BKN20188 HFA18795
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 5C5-5C5   Limits computationally determined from genome sequence between P{EP}CG15770EP390 and P{EP}Act5CEP1604&P{EP}EP444
Experimentally Determined Cytological Location
Cytogenetic map Notes References 5C3-5C3     (Hilfiker, 1996.9.18) 5C3-5C3   (determined by in situ hybridisation)   (Hilfiker et al., 1997)
Experimentally Determined Recombination Data
Location	1-13.8 (Hilfiker et al., 1995, Hilfiker et al., 1998)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mof for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mof-RA FBtr0070829  NM_078496   3017   827
Additional Transcript Data & Comments
Reported size (kB)	3.2 (northern blot) (Hilfiker et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mof-PA   FBpp0070794   92.7   827   4.42     NP_511051   AAF46095
Additional Polypeptide Data & Comments
Reported size (kDa)	827 (aa) (Hilfiker et al., 1997)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • MOZ/SAS-like protein (IPR002717) Chromo domain/shadow (IPR000953) Acyl-CoA N-acyltransferase (IPR016181) Chromo domain-like (IPR016197)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA820460   AA949216   AA951642   AA951643   AA952138   AE014298 AAF46095   AI455435   AI515736   AI520121   AI532144   AI542271   AY102685 AAM27514   BI162284   BI168245   BI172214   BI215011   BI227575   BI229771   BI233039   BI233059   BI234260   BI236685   BI363085   BI483192   BI483590   BI483606   BI580230   BI641971   CO190169   CO264242   CO277135   CO284373   CO319221   CO319826   CO327614   CO329340   CO332219   DN154184   EC067080   EC195506   EC197744   EC211162   EC216174   EC220254   EC235251   EC239726   EC250430   U71219 AAC47507
UniProtKB/Swiss-Prot	O02193
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference larval stage -- adult stage     (Hilfiker et al., 1997)
Additional Descriptive Data
	mof transcript is found in larvae and adults of both sexes. (Hilfiker et al., 1997)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0014340    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0014340 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0014340 expression level Developmental Stage   Expression Level embryo 00-02hr    2821 embryo 02-04hr    3233 embryo 04-06hr    1590 embryo 06-08hr    1770 embryo 08-10hr    1727 embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2821) embryo 02-04hr  (3233) embryo 04-06hr  (1590) embryo 06-08hr  (1770) embryo 08-10hr  (1727) embryo 10-12hr  (1329) embryo 12-14hr  (890) embryo 14-16hr  (1104) embryo 16-18hr  (875) embryo 18-20hr  (445) embryo 20-22hr  (976) embryo 22-24hr  (788) larva L1  (374) larva L2  (289) larva L3 12hr old  (244) larva L3 puffstage 1-2  (276) larva L3 puffstage 3-6  (455) larva L3 puffstage 7-9  (408) white prepupae new  (391) white prepupae 12hr  (506) white prepupae 24hr  (579) pupae 2d postWPP  (308) pupae 3d postWPP  (179) pupae 4d postWPP  (182) adult male 01day  (291) adult male 05day  (394) adult male 30day  (395) adult female 01day  (574) adult female 05day  (896) adult female 30day  (1002) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2821) embryo 02-04hr  (3233) embryo 04-06hr  (1590) embryo 06-08hr  (1770) embryo 08-10hr  (1727) embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2821 embryo 02-04hr    3233 embryo 04-06hr    1590 embryo 06-08hr    1770 embryo 08-10hr    1727 embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2821 embryo 02-04hr    3233 embryo 04-06hr    1590 embryo 06-08hr    1770 embryo 08-10hr    1727 embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0014340 expression level Developmental Stage   Expression Level embryo 00-02hr    2821 embryo 02-04hr    3233 embryo 04-06hr    1590 embryo 06-08hr    1770 embryo 08-10hr    1727 embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2821) embryo 02-04hr  (3233) embryo 04-06hr  (1590) embryo 06-08hr  (1770) embryo 08-10hr  (1727) embryo 10-12hr  (1329) embryo 12-14hr  (890) embryo 14-16hr  (1104) embryo 16-18hr  (875) embryo 18-20hr  (445) embryo 20-22hr  (976) embryo 22-24hr  (788) larva L1  (374) larva L2  (289) larva L3 12hr old  (244) larva L3 puffstage 1-2  (276) larva L3 puffstage 3-6  (455) larva L3 puffstage 7-9  (408) white prepupae new  (391) white prepupae 12hr  (506) white prepupae 24hr  (579) pupae 2d postWPP  (308) pupae 3d postWPP  (179) pupae 4d postWPP  (182) adult male 01day  (291) adult male 05day  (394) adult male 30day  (395) adult female 01day  (574) adult female 05day  (896) adult female 30day  (1002) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2821) embryo 02-04hr  (3233) embryo 04-06hr  1590 embryo 06-08hr  1770 embryo 08-10hr  1727 embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2821 embryo 02-04hr    3233 embryo 04-06hr    1590 embryo 06-08hr    1770 embryo 08-10hr    1727 embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2821 embryo 02-04hr    3233 embryo 04-06hr    1590 embryo 06-08hr    1770 embryo 08-10hr    1727 embryo 10-12hr    1329 embryo 12-14hr    890 embryo 14-16hr    1104 embryo 16-18hr    875 embryo 18-20hr    445 embryo 20-22hr    976 embryo 22-24hr    788 larva L1    374 larva L2    289 larva L3 12hr old    244 larva L3 puffstage 1-2    276 larva L3 puffstage 3-6    455 larva L3 puffstage 7-9    408 white prepupae new    391 white prepupae 12hr    506 white prepupae 24hr    579 pupae 2d postWPP    308 pupae 3d postWPP    179 pupae 4d postWPP    182 adult male 01day    291 adult male 05day    394 adult male 30day    395 adult female 01day    574 adult female 05day    896 adult female 30day    1002 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0014340    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0014340 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0014340 expression level Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0014340 expression level Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    82.35 Larval Midgut    34 Larval Hindgut    41.7 Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland    53.4 Larval Trachea    56.85 Larval Carcass    46.475 Adult Head    25.6 Adult Eye    25.05 Adult Brain    36.9 Adult Thoracic-Abdominal Ganglion    23.6 Adult Crop    25.5 Adult Midgut    24.4 Adult Hindgut    31.8 Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    18.3 Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary    94.5 Adult Testis    27.4 Adult Male Accessory Gland    50.2 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    25.6   NA  Eye    25.05   NA  Brain    36.9   82.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    23.6   NA  Crop    25.5   34  Midgut    24.4   41.7  Hindgut    31.8   no informative data  Malpighian Tubules    no informative data   no informative data  Fat Body    no informative data   53.4  Salivary Gland    no informative data   NA  Heart    18.3   56.85  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    94.5   NA  Testis    27.4   NA  Male Accessory Gland    50.2   46.475  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0014340 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3025-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | male | recessive mof1 viable | female mof1 Sterility Allele female fertile mofT:Zzzz\FLAG,T:Scer\GAL4 Other Phenotypes Allele non-suppressor of variegation, with P{UAS-lacZ.Abd-B.5F24}25,2a mofunspecified wild-type mof+t6.8 mof+t10.8 mof+t18 Phenotype manifest in Allele heart primordium mofdsRNA.cKa mofdsRNA.si.cKa
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of mof Class Mutagen Stocks Known lesion mofG894 P-element activity 1 -- mof1 ethyl methanesulfonate 0 Yes mof2 0 Yes mofunspecified 0 --
Alleles Carried on Transgenic Constructs ( 32 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mof Class Mutagen Stocks Known lesion mofHMS00573 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mofJF01707 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mofKK100092 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes mof+t10.8 in vitro construct - genomic fragment 0 Yes mof+t18 in vitro construct - genomic fragment 0 Yes mof+t6.8 in vitro construct - genomic fragment 0 Yes mof1.MtnA.T:Ivir\HA1 in vitro construct - amino acid replacement 0 Yes mof2.4AS.tub in vitro construct - regulatory fusion 0 Yes mof2.4Δprom in vitro construct - genomic fragment 0 Yes mof2.9Δ3prime in vitro construct - deletion 0 Yes mof3.5promAS in vitro construct 0 Yes mof3prime in vitro construct 0 Yes mofdsRNA.cBa in vitro construct - RNAi 0 Yes mofdsRNA.cKa in vitro construct - RNAi 0 Yes mofdsRNA.si.cKa in vitro construct - RNAi 0 Yes mofGD10025 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes mofhs.PS in vitro construct - regulatory fusion 0 Yes mofhs.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes mofL578G.Y580G.hs.T:Avic\GFP-EGFP in vitro construct - amino acid replacement 0 Yes mofMtnA.cAa.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes mofMtnA.T:Ivir\HA1 in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes mofScer\FRT.tub in vitro construct - regulatory fusion 0 Yes moft3.5 in vitro construct - genomic fragment 0 Yes moft6.7 in vitro construct - genomic fragment 0 Yes mofT:Zzzz\FLAG,T:Scer\GAL4 in vitro construct - regulatory fusion 0 Yes moftHa in vitro construct - genomic fragment 0 Yes moftub.PKa in vitro construct - regulatory fusion 0 Yes moftub.PKb FLPase 0 Yes moftub.T:Zzzz\TAP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes mofW426G.MtnA.T:Ivir\HA1 in vitro construct - amino acid replacement 0 Yes mofY416D.hs.T:Avic\GFP-EGFP in vitro construct - amino acid replacement 0 Yes mofY416D.MtnA.T:Ivir\HA1 in vitro construct - amino acid replacement 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6237 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10025} NA P{KK100092} NA P{TRiP.HMS00573} NA P{TRiP.JF01707} NA heat-shock construct P{hs-mof} NA characterization construct P{mof2.4Δprom} NA P{mof2.9Δ3prime} NA P{mof3.5promAS} NA P{mof3prime} NA P{mof+.HH} NA P{mof+.SS} NA P{mof+.XB} NA P{mof+.XK} NA P{moft3.5} NA P{moft6.7} NA P{tub(FRT.y+)mof.Kb} NA P{tub(-FRT)mof.Kb} NA P{tub-mof.2.4AS} NA P{tub-mof.Ka} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}mofG894 NA
Gene Ontology: Function, Process & Cellular Component ( 13 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
chromatin binding inferred from direct assay (Straub et al., 2008)
Biological Process
CV term Evidence References
dosage compensation inferred from genetic interaction with msl-2 AND inferred from mutant phenotype (Hilfiker et al., 1997)
Cellular Component
CV term Evidence References
transcription factor complex inferred from direct assay (Prestel et al., 2010) X chromosome located dosage compensation complex, transcription activating inferred from direct assay (Prestel et al., 2010)
Terms Based on Predictions or Assertions ( 11 terms )
Molecular Function
CV term Evidence References
histone acetyltransferase activity inferred from sequence or structural similarity with Saccharomyces ESA1 (FlyBase, 1992-) inferred from sequence or structural similarity with Saccharomyces SAS2 AND inferred from sequence or structural similarity with Saccharomyces SAS3 (Hilfiker et al., 1997) non-traceable author statement (Hilfiker, 1996.9.18, Swiss-Prot Project Members, 1998.2.1) traceable author statement (Carrozza et al., 2003, Amrein, 2000, Wutz, 2003) histone acetyltransferase activity (H4-K16 specific) traceable author statement (Brehm et al., 2004) lysine N-acetyltransferase activity traceable author statement (Carrozza et al., 2003) mRNA binding traceable author statement (Amrein, 2000, Wutz, 2003)
Biological Process
CV term Evidence References
dosage compensation non-traceable author statement (Swiss-Prot Project Members, 1998.2.1) dosage compensation, by hyperactivation of X chromosome non-traceable author statement (FlyBase, 1992-, Schutt and Nothiger, 2000) histone acetylation non-traceable author statement (Swiss-Prot Project Members, 1998.2.1) traceable author statement (Carrozza et al., 2003, Amrein, 2000) peptidyl-lysine acetylation traceable author statement (Carrozza et al., 2003) regulation of transcription, DNA-dependent inferred from electronic annotation with InterPro:IPR002717 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
X chromosome traceable author statement (Brehm et al., 2004) X chromosome located dosage compensation complex, transcription activating non-traceable author statement (FlyBase, 1992-, Schutt and Nothiger, 2000, Wutz, 2003) traceable author statement (Amrein, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mof allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0014340 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31518
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21061 Dere\GG18463 Dgri\GH11980 Dmoj\GI14721 Dper\GL15211 Dpse\GA15730 Dsec\GM12611 Dvir\GJ16786 Dwil\GK16378 Dyak\GE15686
Curated drosophilid orthologs	Dpse\GA15730   Dsim\mof (Pal Bhadra et al., 2006)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL007672-PA Aedes aegypti (mosquito) AGAP012229-PA Anopheles gambiae (mosquito) XP_625075.1 Apis mellifera (honey bee) XP_001947167.1 Acyrthosiphon pisum (pea aphid) At5g09740.1 Arabidopsis thaliana (wall cress) At5g64610.1 Arabidopsis thaliana (wall cress) 123896 Branchiostoma floridae (lancelet) XP_001893021.1 Brugia malayi (roundworm nematode) BGIBMGA006995-PA Bombyx mori (silk worm) ENSBTAP00000013893 Bos taurus (bovine) CBP28998 Caenorhabditis briggsae (nematode) CE23850 Caenorhabditis elegans (worm) ENSCAFP00000024765 Canis familiaris (dog) ENSCINP00000015650 Ciona intestinalis (sea squirt) JA07701 Caenorhabditis japonica (nematode) CML102C Cyanidioschyzon merolae (red alga) CPIJ005726 Culex pipens (mosquito) ENSCPOP00000000899 Cavia porcellus (guinea pig) 192045 Chlamidomonas reinhardtii (green alga) 138964 Capitella spl (polychaete worm) DDB0233629 Dictyostelium discoideum (amoeba) 302096 Daphnia pulex (daphnia) ENSDARP00000029877 Danio rerio (zebra fish) ENSECAP00000016311 Equus caballus (horse) ENSGACP00000019702 Gymnopilus aculeatus (mushroom) 95818 Hypsipyla robusta (cedar shoot borer) ENSP00000219797 Homo sapiens (human) ISCW020926-PA Ixodes scapularis (deer tick) 195151 Lottia gigantea (owl limpet) ENSMODP00000002268 Monodelphis domestica (gray opossum) ENSMUSP00000033070 Mus musculus (house mouse) 167841 Nematostella vectensis (starlet anemone) XP_001600240.1 Nasonia vitripennis (wasp) ENSORLP00000001403 Oryzias latipes (japanese killifish) 19027 Ostreococcus tauri (green alga) PHUM001380-PA Pediculus humanus (human body louse) ENSPPYP00000008256 Pongo pygmaeus (orangutan) ENSRNOP00000026527 Rattus norvegicus (norway rat) Smp_194520 Schistosoma mansoni (trematode parasite) 55881 Trichoplax adhaerens (metazoa) XP_968431.1 Tribolium castaneum (red flour beetle) ENSTNIP00000014236 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000009260 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000004144 Xenopus tropicalis (frog) YALI0D26598g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18796 NV15786 LH14120 ISCW020926 FBgn0233254 FBgn0218380 FBgn0203965 FBgn0167547 JGI_V11_302096 FBgn0075747 FBgn0152815 FBgn0137472 FBgn0127072 FBgn0119459 FBgn0110676 FBgn0098066 CPIJ005726 BGIBMGA006995 ACYPI007995 ACYPI002102 GB15903 AGAP012229 AAEL007672 PHUM284900 GLEAN_03573
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	26610 w* P{EP}mofG894 31401 y1 v1; P{TRiP.JF01707}attP2 33698 y1 sc* v1; P{TRiP.HMS00573}attP2/TM3, Sb1
VDRC	v105370 P{KK100092}VIE-260B
Genomic Clones ( 1 )
	BACR11C13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 43 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD24203
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD28029 LD29211 LD32279 LD32280 LD40125 LD41389 RE01649 RE08841 RE14509 RE21191 RE24664 RE27622 RE29323 RE29335 RE29935 RE32778 RE47811 RE66044 RE66507 RE66523 RE74383 SD03525 SD08503 SD25664
Other clones	1679 51603 66024 176159 190480 275149 CK01.58A.C12 CK01.141A.F2 EK046842 EK123134 EK138304 EK165919 EK193610 EK276760 EK280957 EK292633 EK302825 EP07708
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0014340 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31518
Antibody Information
	polyclonal (Prestel et al., 2010)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: mof CG3025 (Zhong, 1999.11)
Source for database merge of
Additional comments
Other Comments
	mof protein distributes dynamically between two complexes, the dosage compensation complex and a complex containing MBD-R2 protein, a global facilitator of transcription. (Prestel et al., 2010) Gene expression is increased in response to the presence of two copies of Scer\GAL4hs.PB. (Liu and Lehmann, 2008) Gene products of the male specific lethal (msl) group of genes including msl-1, msl-2, msl-3, mle, and mof are associated with all female chromosomes at a low level but are sequestered to the X chromosome in males. There is evidence for the presence of nucleation sites for association of msl proteins with the X chromosome rather than individual gene binding sites. mof is still capable of associating with the chromosome in msl mutant individuals. It appears to be able to dissociate from other members of the MSL complex under these circumstances and act independently. (Bhadra et al., 1999) Gene products of the male specific lethal (msl) group of genes preferentially associate with the male X chromosome and may have a role in dosage compensation. This may be achieved by regulating an inverse dosage effect, which would be maintained on the male X and nullified on the autosomes. (Bhadra et al., 1999) mof colocalises with the MSL complex on the X chromosome: a sequence of binding events results in the formation of the MSL complex on the X chromosome in males and in the targeting of mof to its presumed site of action. (Gu et al., 1998) mof encodes a putative histone acetyl transferase (HAT) that plays a direct role in the specific histone acetylation associated with dosage compensation, the male-specific hypertranscription of X-linked genes. mof function in dosage compensation is supported by the effect of the mutation on the binding of other dosage compensation regulatory factors to the X chromosome and its effect on the normal consequences that this binding has on nucleosomal structure. (Hilfiker et al., 1997) Male lethal locus that exhibits a strong maternal effect and is responsible for dosage compensation in males. (Hilfiker et al., 1995)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078496 RefSeq (Proteins) • NP_511051 DDBJ / EMBL / GenBank • AA820460 AAC47507 AAF46095 AAM27514 AI455435 AY102685 U71219 Entrez Gene - A searchable database of RefSeq genes. • 31518 UniProtKB/Swiss-Prot • O02193
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • MOZ/SAS-like protein (IPR002717) Chromo domain/shadow (IPR000953) Acyl-CoA N-acyltransferase (IPR016181) Chromo domain-like (IPR016197)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0014340 DRSC - Results from RNAi screens. • FBgn0014340 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0014340 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3025-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0014340 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31518 InParanoid A subset of ortholog calls from InParanoid. • AAEL007672-PA Aedes aegypti (mosquito) AGAP012229-PA Anopheles gambiae (mosquito) XP_625075.1 Apis mellifera (honey bee) XP_001947167.1 Acyrthosiphon pisum (pea aphid) At5g09740.1 Arabidopsis thaliana (wall cress) At5g64610.1 Arabidopsis thaliana (wall cress) 123896 Branchiostoma floridae (lancelet) XP_001893021.1 Brugia malayi (roundworm nematode) BGIBMGA006995-PA Bombyx mori (silk worm) ENSBTAP00000013893 Bos taurus (bovine) CBP28998 Caenorhabditis briggsae (nematode) CE23850 Caenorhabditis elegans (worm) ENSCAFP00000024765 Canis familiaris (dog) ENSCINP00000015650 Ciona intestinalis (sea squirt) JA07701 Caenorhabditis japonica (nematode) CML102C Cyanidioschyzon merolae (red alga) CPIJ005726 Culex pipens (mosquito) ENSCPOP00000000899 Cavia porcellus (guinea pig) 192045 Chlamidomonas reinhardtii (green alga) 138964 Capitella spl (polychaete worm) DDB0233629 Dictyostelium discoideum (amoeba) 302096 Daphnia pulex (daphnia) ENSDARP00000029877 Danio rerio (zebra fish) ENSECAP00000016311 Equus caballus (horse) ENSGACP00000019702 Gymnopilus aculeatus (mushroom) 95818 Hypsipyla robusta (cedar shoot borer) ENSP00000219797 Homo sapiens (human) ISCW020926-PA Ixodes scapularis (deer tick) 195151 Lottia gigantea (owl limpet) ENSMODP00000002268 Monodelphis domestica (gray opossum) ENSMUSP00000033070 Mus musculus (house mouse) 167841 Nematostella vectensis (starlet anemone) XP_001600240.1 Nasonia vitripennis (wasp) ENSORLP00000001403 Oryzias latipes (japanese killifish) 19027 Ostreococcus tauri (green alga) PHUM001380-PA Pediculus humanus (human body louse) ENSPPYP00000008256 Pongo pygmaeus (orangutan) ENSRNOP00000026527 Rattus norvegicus (norway rat) Smp_194520 Schistosoma mansoni (trematode parasite) 55881 Trichoplax adhaerens (metazoa) XP_968431.1 Tribolium castaneum (red flour beetle) ENSTNIP00000014236 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000009260 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000004144 Xenopus tropicalis (frog) YALI0D26598g Yarrowia lipolytica (nonconventional yeast) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /polycomb/maleab1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31518 modMine - Data generated by the modENCODE project. • FBgn0014340 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18796 NV15786 LH14120 ISCW020926 FBgn0233254 FBgn0218380 FBgn0203965 FBgn0167547 JGI_V11_302096 FBgn0075747 FBgn0152815 FBgn0137472 FBgn0127072 FBgn0119459 FBgn0110676 FBgn0098066 CPIJ005726 BGIBMGA006995 ACYPI007995 ACYPI002102 GB15903 AGAP012229 AAEL007672 PHUM284900 GLEAN_03573
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	CG3025 (Kim et al., 2004, Keleman et al., 2009.8.5, Ni et al., 2008, Ni et al., 2010.12.1) dmMOF (Pandey et al., 2002) dMOF (Carrozza et al., 2003, Li et al., 2007, Bell et al., 2007) max (Hilfiker et al., 1998, Lucchesi, 1996, Hilfiker, 1995.5.26, Hilfiker et al., 1995, ) MOF (Nusinow, 2005, de la Cruz et al., 2005, Kelley, 2004, Kellum, 2003, Bouazoune et al., 2002, Akhtar and Becker, 2001, Rattner and Meller, 2001, Kelley and Kuroda, 2000, Scott et al., 2000, Smith et al., 2000, Kouzarides, 1999, Park et al., 2006, Straub and Becker, 2007, Dahlsveen et al., 2006, Nielsen et al., 2005, Deng and Meller, 2006, Morra et al., 2007, Gilfillan et al., 2006, Furuhashi et al., 2006, Straub et al., 2005, Roy et al., 2007, Deng and Meller, 2006, Mendjan and Akhtar, 2007, Birchler et al., 2006, Birchler et al., 2008, Morales et al., 2005, Li et al., 2005, Park et al., 2007, Kind et al., 2008, Akhtar and Becker, 2001, Patalano et al., 2009, Straub et al., 2008, Corona et al., 2002, Buscaino et al., 2006, Grimaud and Becker, 2009, Raja et al., 2010, Vaquerizas et al., 2010, Regnard et al., 2011, Schiemann et al., 2010, Sural et al., 2008, Schiemann et al., 2010, Andersen et al., 2010) Mof (Kouzarides, 1998, Schwaiger et al., 2009, Kim et al., 2005) mof (Mendjan et al., 2006, Ray and Fox, 2005, Schubeler, 2006, Furuhashi et al., 2006, Gan et al., 2010, Prestel et al., 2010, Pal Bhadra et al., 2006, Liu and Lehmann, 2008, Kind and Akhtar, 2007, Rodriguez et al., 2007, Morra et al., 2008, Yokoyama et al., 2007, Worringer and Panning, 2007, Li et al., 2008, Bell et al., 2008, Levine et al., 2007, Zhimulev et al., 2003, Gelbart et al., 2009, Kulkarni-Shukla et al., 2008, Menon and Meller, 2009, Gim et al., 2001, Zhang et al., 2010, Spierer et al., 2008, Prabhakaran and Kelley, 2010, Yu et al., 2010, Gladstein et al., 2010) unnamed (Hilfiker et al., 1995)
Name Synonym	Males absent on first (Deng and Meller, 2006) males absent on first (Raja et al., 2010, Prabhakaran and Kelley, 2010) males absent on the first (Birchler et al., 2006, Kulkarni-Shukla et al., 2008) males-absent-on-the-first (Morales et al., 2005) Males absent on the first (Gim et al., 2001) males-absent on the X (Hilfiker, 1995.5.26, ) MOF histone acetylase (Sun and Birchler, 2007)
Secondary FlyBase IDs
References ( 168 )
Generate a list of	All references relating to this gene ( 168 )
List References by type	Research paper  ( 84 ) Supplementary material  ( 2 ) Review  ( 45 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 22 ) FlyBase analysis  ( 1 ) Conference report  ( 1 ) Curated genome annotation  ( 2 ) DNA/RNA sequence record  ( 1 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 12 )
	Regnard et al., 2011, PLoS Genet. 7(3): e1001327 Global Analysis of the Relationship between JIL-1 Kinase and Transcription. [FBrf0213276] Andersen et al., 2010, Mol. Cell. Biol. 30(19): 4744--4755 Drosophila MCRS2 Associates with RNA Polymerase II Complexes To Regulate Transcription. [FBrf0211794] Gan et al., 2010, Cell Res. 20(7): 763--783 Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq. [FBrf0211191] Gladstein et al., 2010, PLoS Genet. 6(7): e1001041 Requirement of male-specific dosage compensation in Drosophila females-implications of early X chromosome gene expression. [FBrf0211448] Prabhakaran and Kelley, 2010, BMC Biol. 8: 80 A new strategy for isolating genes controlling dosage compensation in Drosophila using a simple epigenetic mosaic eye phenotype. [FBrf0211122] Prestel et al., 2010, Mol. Cell 38(6): 815--826 The Activation Potential of MOF Is Constrained for Dosage Compensation. [FBrf0211211] Raja et al., 2010, Mol. Cell 38(6): 827--841 The Nonspecific Lethal Complex Is a Transcriptional Regulator in Drosophila. [FBrf0211222] Schiemann et al., 2010, BMC Mol. Biol. 11: 80 Sex-biased transcription enhancement by a 5' tethered Gal4-MOF histone acetyltransferase fusion protein in Drosophila. [FBrf0212392] Schiemann et al., 2010, Biochem. Biophys. Res. Commun. 402(4): 699--704 The importance of location and orientation of male specific lethal complex binding sites of differing affinities on reporter gene dosage compensation in Drosophila. [FBrf0212385] Vaquerizas et al., 2010, PLoS Genet. 6(2): e1000846 Nuclear pore proteins nup153 and megator define transcriptionally active regions in the Drosophila genome. [FBrf0210058] Yu et al., 2010, genesis 48(3): 161--170 E(nos)/CG4699 required for nanos function in the female germ line of Drosophila. [FBrf0210233] Zhang et al., 2010, PLoS Biol. 8(2): e1000320 Expression in aneuploid Drosophila s2 cells. [FBrf0210115] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...