FlyBase Gene Report: Dmel\noi

U2 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE -: The U2 small nuclear ribonucleoprotein particle (U2 snRNP) contains U2 snRNA. It is recruited to the spliceosome after U1 snRNP and forms a stable interaction with the branch site and 3' splice site in pre-mRNA. (Adapted from PMID:23829528 and PMID:21441581).
SPLICEOSOME COMPLEX A -: Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex A, the pre-spliceosome, is composed of U1 and U2 snRNPs and proteins involved in recognition of the 5' splice site and branch point. (Adapted from PMID:24452469 and PMID:23118483).
SPLICEOSOME COMPLEX B -: Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. After the assembly of complex A on pre-mRNA, the U4-U6 and U5 snRNPs are recruited as a preassembled tri-snRNP to form complex B. U5 snRNP binds exons at the 5' site. (Adapted from PMID:24452469 and PMID:23118483).
SPLICEOSOME COMPLEX C -: Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex B undergoes a number of structural rearrangements and U4 and U1 snRNPs dissociate to generate complex C, the catalytic spliceosome. (Adapted from PMID:24452469 and PMID:23118483).
SPLICEOSOME COMPLEX P -: Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex P, the post-spliceosomal complex, is formed after the catalytic removal of the intron by complex C. Complex P contains the lariat intron and spliced exons. (Adapted from PMID:24452469 and PMID:23118483).

Protein Function (UniProtKB)

Probable subunit of a splicing factor complex required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (By similarity). Involved in male fertility.

(UniProt, O46106)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\noi or the JBrowse view of Dmel\noi for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.48

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

noi-RA

FBtr0078751

NM_057766

1859

503

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

noi-PA

FBpp0078400

58.4

503

5.34

NP_477114

AAF51999

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Probable component of a the U2 small nuclear ribonucleoproteins complex (U2 snRNP).

(UniProt, O46106)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\noi using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

noi_1

Linkouts

Gene Ontology (9 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

RNA binding

inferred from sequence or structural similarity with HGNC:10767

(FlyBase Curators, 2008--)

inferred from biological aspect of ancestor with PANTHER:PTN000300247

(assigned by GO_Central )

(Gaudet et al., 2011)

zinc ion binding

inferred from electronic annotation with InterPro:IPR000690

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Biological Process (3 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

fertilization

inferred from mutant phenotype

(assigned by UniProt )

(Meyer et al., 1998)

mitotic cell cycle

inferred from high throughput mutant phenotype

(Ducat et al., 2008)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

mRNA splicing, via spliceosome

inferred from sequence or structural similarity with SGD:S000002188

(Mount and Salz, 2000)

inferred by curator from GO:0071011,GO:0071013

(Herold et al., 2009)

inferred from biological aspect of ancestor with PANTHER:PTN000300247

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

catalytic step 2 spliceosome

inferred from high throughput direct assay

(Herold et al., 2009)

precatalytic spliceosome

inferred from high throughput direct assay

(Herold et al., 2009)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

spliceosomal complex

inferred from biological aspect of ancestor with PANTHER:PTN000300247

(assigned by GO_Central )

(Gaudet et al., 2011)

U2 snRNP

inferred from sequence or structural similarity with SGD:S000002188

(Mount and Salz, 2000)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | faint | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

catalytic step 2 spliceosome

inferred from high throughput direct assay

(Herold et al., 2009)

precatalytic spliceosome

inferred from high throughput direct assay

(Herold et al., 2009)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\noi in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\noi

View exonic expression by tissue for Dmel\noi

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0014366

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0014366

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG2925-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2925

Flygut - An atlas of the Drosophila adult midgut

FBgn0014366

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 12 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of noi

Transgenic constructs containing regulatory region of noi

Deletions and Duplications ( 4 )

Disrupted in

Df(3R)BSC549

(Christensen et al., 2008.6.11)

Df(3R)Exel6144

(Ryder, 2004.4.26)

Df(3R)noi-B

(Buffin et al., 2007, Meyer et al., 1998)

Df(3R)noi-C

(Meyer et al., 1998)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Mef2.PU

noi^GD9855

lethal, with Scer\GAL4^pnr-MD237

noi^GD9855

lethal, with Scer\GAL4^VP16.otu

noi^HMS00163

lethal | recessive

noi^j3E7

lethal - all die before end of embryonic stage | recessive

lethal - all die during larval stage, with Scer\GAL4^Mef2.PR

noi^GD9855

partially lethal, with Scer\GAL4^tin.CΔ4

noi^GD9855

viable

noi²⁰

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

noi^GD9855

viable | female

viable | male

Sterility

Allele

female sterile | cold sensitive

male sterile | recessive

Other Phenotypes

Allele

flight defective, with Scer\GAL4^Act88F.PU

flight defective, with Scer\GAL4^Mef2.PU

noi^HMS00163

some die during embryonic stage | recessive

some die during pupal stage, with Scer\GAL4^Act88F.PU

noi^GD9855

visible

noi²⁰

visible, with Scer\GAL4^nub-AC-62

noi^HMS00163

wild-type

noi^+t3.6

Phenotype manifest in

Allele

dorsal appendage

egg

embryonic/larval somatic muscle, with Scer\GAL4^Mef2.PR

noi^GD9855

germline cell | male

head & macrochaeta | dorsal

noi²⁰

indirect flight muscle | pharate adult stage, with Scer\GAL4^Mef2.PU

noi^HMS00163

medial triple row

noi²⁰

myofibril | pharate adult stage, with Scer\GAL4^Mef2.PU

noi^HMS00163

nurse cell

nurse cell & nucleus

oocyte nucleus

sarcomere, with Scer\GAL4^Mef2.PR

noi^GD9855

sex comb

noi²⁰

thorax & macrochaeta | dorsal

noi²⁰

wing, with Scer\GAL4^nub-AC-62

noi^HMS00163

Z disc, with Scer\GAL4^Mef2.PR

noi^GD9855

Z disc | pharate adult stage, with Scer\GAL4^Mef2.PU

noi^HMS00163

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\SF3A3

15 of 15

Yes

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Sf3a3

14 of 15

Yes

Rattus norvegicus (Norway rat) (1)

Rnor\Sf3a3

11 of 13

Yes

Xenopus tropicalis (Western clawed frog) (1)

Xtro\sf3a3

12 of 12

Yes

Danio rerio (Zebrafish) (1)

Drer\sf3a3

12 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

Cele\T13H5.4

15 of 15

Yes

Arabidopsis thaliana (thale-cress) (1)

Atha\ATO

9 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\PRP9

14 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (2)

Spom\sap61

11 of 12

Yes

Spom\pcp1

1 of 12

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091906ZR )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\noi

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00009207

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00010884

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA15523

Drosophila persimilis

Dper\GL21522

Drosophila willistoni

Dwil\GK22655

Drosophila virilis

Dvir\GJ24013

Drosophila mojavensis

Dmoj\GI23921

Drosophila grimshawi

Dgri\GH17377

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503R8 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17011498

Glossina morsitans

Tsetse fly

Gmor\GMOY011327

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_10782

Mayetiola destructor

Hessian fly

Mdes\Mdes009822

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL015244

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL012348

Anopheles darlingi

American malaria mosquito

Adar\ADAC001095

Anopheles gambiae

Malaria mosquito

Agam\AGAP003085

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ002728

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W03JE )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA006358

Danaus plexippus

Monarch butterfly

Dple\DPOGS207617-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL007862

Apis florea

Little honeybee

Aflo\2324838980

Apis mellifera

Western honey bee

Amel\SF3A3

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP14832

Bombus terrestris

Buff-tailed bumblebee

Bter\15205604

Linepithema humile

Argentine ant

Lhum\LH12891

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:002063

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG007268

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_01699

Tribolium castaneum

Red flour beetle

Tcas\TC001034

Pediculus humanus

Human body louse

Phum\PHUM258680

Rhodnius prolixus

Kissing bug

Rpro\RPRC010937

Cimex lectularius

Bed bug

Clec\CLEC006021

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI000249

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_08506

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X03G1 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR007390

Ixodes scapularis

Black-legged tick

Isca\ISCW010835

Stegodyphus mimosarum

African social velvet spider

Smim\KFM83108.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur23g00810

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_216576

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G059G )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Sf3a3_1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Sf3a3

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000002730

Gallus gallus

Domestic chicken

Ggal\SF3A3

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (1)

Gene Symbol

Score

Source

Alignment

2 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SF3A3; splicing factor 3a subunit 3

15 of 15

605596

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

noi - Sf3a1

experimental knowledge based

(Guruharsha et al., 2011)

noi - Sf3a2

experimental knowledge based

(Guruharsha et al., 2011)

noi - Sf3b5

anti tag coimmunoprecipitation, peptide massfingerprinting

(Stegeman et al., 2016)

noi - snf

anti tag coimmunoprecipitation, peptide massfingerprinting

(Stegeman et al., 2016)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

snf|Sxl

enhanceable

noi

(Cline et al., 1999)

Sxl|snf

suppressible

noi

(Cline et al., 1999)

External Data

Subunit Structure (UniProtKB)

Probable component of a the U2 small nuclear ribonucleoproteins complex (U2 snRNP).

(UniProt, O46106 )

Linkouts

BioGRID - A database of protein and genetic interactions.

65884

DroID - A comprehensive database of gene and protein interactions.

FBgn0014366

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

40678

MIST (genetic) - An integrated Molecular Interaction Database

MIST (protein-protein) - An integrated Molecular Interaction Database

Pathways

Gene Group - Pathway Membership (FlyBase)

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-47.5

Cytogenetic map

83B4-83B4

Sequence location

3R:5,589,601..5,591,459 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

83B4-83B4

Limits computationally determined from genome sequence between P{PZ}Snr1⁰¹³¹⁹&P{PZ}Itp-r83A⁰⁵⁶¹⁶ and P{lacW}Atu^s1938

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

83B1-83B2

(determined by in situ hybridisation)

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

83B-83B

(determined by in situ hybridisation)

(Meyer et al., 1998)

Experimentally Determined Recombination Data

Location

3-47.5

(FlyBase, 2016)

3-44.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Bloomington

18865

w¹¹¹⁸; PBac{WH}noi^f05442/TM6B, Tb¹

34845

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00163}attP2

21799

y¹ w^67c23; P{Mae-UAS.6.11}noi^DP00123/TM3, Sb¹

10214

w¹¹¹⁸; P{lacW}Vha26^j3E7/TM3, P{ftz-lacC}SC1, ry^RK Sb¹ Ser¹

f05270

f05442

v105354

v20943

w¹¹¹⁸; P{GD9855}v20943

v20945

w¹¹¹⁸; P{GD9855}v20945/TM3

Genomic Clones (10)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (36)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

LD22754

Other clones

DPiM_LD22754

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0014366

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0014366

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40678

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: noi l(3)j3E7

(Spradling et al., 1999)

Additional comments

Other Comments

RNAi screen using dsRNA made from templates generated with primers directed against this gene results in a long metaphase spindle with misaligned chromosomes when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.

(Goshima et al., 2007)

Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells.

(Nybakken et al., 2005)

RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R⁺ cells.

(Boutros et al., 2004)

Hypomorphic alleles reveal multiple roles of noi for the survival and differentiation of male germ cells, the differentiation of female germ cells and the development of several adult structures.

(Meyer et al., 1998)

Complete loss of noi function results in lethality at the end of embryogenesis, without obvious morphological defects.

(Meyer et al., 1998)

noi is required for the maintenance of the XY male germline stem cells and the few escaping germ cells fail to develop.

(Pauli et al., 1995)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 44 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40678

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

O46106

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0014366

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0014366

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

noi_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG2925

Flygut - An atlas of the Drosophila adult midgut

FBgn0014366

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40678

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG2925

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Spliceosome

modMine - A data warehouse for the modENCODE project

FBgn0014366

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

mRNA Splicing - Major Pathway

Linkouts

BioGRID - A database of protein and genetic interactions.

65884

DPiM - Drosophila Protein interaction map

FBgn0014366

DroID - A comprehensive database of gene and protein interactions.

FBgn0014366

DRSC - Results frm RNAi screens

FBgn0014366

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0014366

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG2925-RA

FlyMine - An integrated database for Drosophila genomics

FBgn0014366

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

40678

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Spliceosome

MIST (genetic) - An integrated Molecular Interaction Database

MIST (protein-protein) - An integrated Molecular Interaction Database

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

mRNA Splicing - Major Pathway

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

CG2925

(Çiçek et al., 2016, Stegeman et al., 2016, Ni et al., 2011.7.19, Tsoi et al., 2011, Herold et al., 2009, Keleman et al., 2009.8.5, Ducat et al., 2008, Goshima et al., 2007, Nybakken et al., 2005, Mount and Salz, 2000)

Noi

(Gwack et al., 2007)

SF3A3

(Nikonova et al., 2019, Stegeman et al., 2016, Somma et al., 2008)

SF3a⁶⁰

(Cline et al., 1999)

l(3)j3E7

(BDGP Project Members, 1994-1999)

ms3225

(Laget et al., 1996)

noi

(Nikonova et al., 2019, Japanese National Institute of Genetics, 2012.5.21, Guest et al., 2011, Herold et al., 2009, Christensen et al., 2008.6.11, Farny et al., 2008, Font-Burgada et al., 2008, Somma et al., 2008, Xi et al., 2008, Buffin et al., 2007, Goshima et al., 2007, Nybakken et al., 2005, Meyer et al., 1998)

Name Synonyms

Noisette

(Ducat et al., 2008)

noisette

(Buffin et al., 2007, Pauli, 1998.1.5, Pauli et al., 1995)

Secondary FlyBase IDs

FBgn0011357

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Study focus (0)

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References (60)

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