FB2020_06, released Dec 22, 2020

Gene: Dmel\noi

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General Information
Symbol
Dmel\noi
Species
D. melanogaster
Name
noisette
Annotation Symbol
CG2925
Feature Type
protein_coding_gene
FlyBase ID
FBgn0014366
Gene Model Status
Current
Stock Availability
7 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Also Known As

SF3A3, l(3)j3E7

Key Links
Genomic Location
Cytogenetic map
83B4-83B4
Sequence location
3R:5,589,601..5,591,459 [-]
Recombination map

3-47.5

RefSeq locus
NT_033777 REGION:5589601..5591459
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (9 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables RNA binding
inferred from sequence or structural similarity with HGNC:10767
(FlyBase Curators, 2008--)
inferred from biological aspect of ancestor with PANTHER:PTN000300247
(assigned by GO_Central )
(Gaudet et al., 2011)
enables zinc ion binding
inferred from electronic annotation with InterPro:IPR000690
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Biological Process (3 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
involved_in fertilization
inferred from mutant phenotype
(assigned by UniProt )
(Meyer et al., 1998)
involved_in mitotic cell cycle
inferred from high throughput mutant phenotype
(Ducat et al., 2008)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in mRNA splicing, via spliceosome
inferred from sequence or structural similarity with SGD:S000002188
(Mount and Salz, 2000)
inferred by curator from GO:0071011,GO:0071013
(Herold et al., 2009)
inferred from biological aspect of ancestor with PANTHER:PTN000300247
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
part_of catalytic step 2 spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
part_of precatalytic spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
part_of spliceosomal complex
inferred from biological aspect of ancestor with PANTHER:PTN000300247
(assigned by GO_Central )
(Gaudet et al., 2011)
part_of U2 snRNP
inferred from sequence or structural similarity with SGD:S000002188
(Mount and Salz, 2000)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the SF3A3 family. (O46106)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
U2 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE -
The U2 small nuclear ribonucleoprotein particle (U2 snRNP) contains U2 snRNA. It is recruited to the spliceosome after U1 snRNP and forms a stable interaction with the branch site and 3' splice site in pre-mRNA. (Adapted from PMID:23829528 and PMID:21441581).
SPLICEOSOME COMPLEX A -
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex A, the pre-spliceosome, is composed of U1 and U2 snRNPs and proteins involved in recognition of the 5' splice site and branch point. (Adapted from PMID:24452469 and PMID:23118483).
SPLICEOSOME COMPLEX B -
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. After the assembly of complex A on pre-mRNA, the U4-U6 and U5 snRNPs are recruited as a preassembled tri-snRNP to form complex B. U5 snRNP binds exons at the 5' site. (Adapted from PMID:24452469 and PMID:23118483).
SPLICEOSOME COMPLEX C -
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex B undergoes a number of structural rearrangements and U4 and U1 snRNPs dissociate to generate complex C, the catalytic spliceosome. (Adapted from PMID:24452469 and PMID:23118483).
SPLICEOSOME COMPLEX P -
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex P, the post-spliceosomal complex, is formed after the catalytic removal of the intron by complex C. Complex P contains the lariat intron and spliced exons. (Adapted from PMID:24452469 and PMID:23118483).
Protein Function (UniProtKB)
Probable subunit of a splicing factor complex required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA (By similarity). Involved in male fertility.
(UniProt, O46106)
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\noi for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.48

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
noi-RA
FBtr0078751
NM_057766
1859
503
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
noi-PA
FBpp0078400
58.4
503
5.34
NP_477114
AAF51999
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Subunit Structure (UniProtKB)

Probable component of a the U2 small nuclear ribonucleoproteins complex (U2 snRNP).

(UniProt, O46106)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\noi using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
organism | faint | ubiquitous
(Fisher et al., 2012)
embryonic stage 11 -- 12
organism | faint | ubiquitous
(Fisher et al., 2012)
embryonic stage 13 -- 16
organism | faint | ubiquitous
(Fisher et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
part_of catalytic step 2 spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
part_of precatalytic spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\noi in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 12 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of noi
Transgenic constructs containing regulatory region of noi
Deletions and Duplications ( 4 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal, with Scer\GAL4Mef2.PU
lethal, with Scer\GAL4pnr-MD237
lethal, with Scer\GAL4VP16.otu
lethal | recessive
lethal - all die before end of embryonic stage | recessive
lethal - all die during larval stage, with Scer\GAL4Mef2.PR
partially lethal, with Scer\GAL4tin.CΔ4
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable | female
viable | male
Sterility
Allele
female sterile | cold sensitive
male sterile | recessive
Other Phenotypes
Allele
flight defective, with Scer\GAL4Act88F.PU
flight defective, with Scer\GAL4Mef2.PU
size defective | third instar larval stage, with Scer\GAL4Cg.PA
some die during embryonic stage | recessive
some die during pupal stage, with Scer\GAL4Act88F.PU
visible
visible, with Scer\GAL4nub-AC-62
wild-type
Phenotype manifest in
Allele
dorsal appendage
egg
embryonic/larval fat body | third instar larval stage, with Scer\GAL4Cg.PA
embryonic/larval somatic muscle, with Scer\GAL4Mef2.PR
germline cell | male
head & macrochaeta | dorsal
indirect flight muscle | pharate adult stage, with Scer\GAL4Mef2.PU
medial triple row
mitochondrion | third instar larval stage, with Scer\GAL4Cg.PA
myofibril | pharate adult stage, with Scer\GAL4Mef2.PU
nurse cell
nurse cell & nucleus
oocyte nucleus
sarcomere, with Scer\GAL4Mef2.PR
sex comb
thorax & macrochaeta | dorsal
wing, with Scer\GAL4nub-AC-62
Z disc, with Scer\GAL4Mef2.PR
Z disc | pharate adult stage, with Scer\GAL4Mef2.PU
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\SF3A3
15 of 15
Yes
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Sf3a3
14 of 15
Yes
Yes
Rattus norvegicus (Norway rat) (1)
Rnor\Sf3a3
12 of 13
Yes
Yes
Xenopus tropicalis (Western clawed frog) (1)
Xtro\sf3a3
13 of 12
Yes
Yes
Danio rerio (Zebrafish) (1)
Drer\sf3a3
11 of 15
Yes
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\T13H5.4
15 of 15
Yes
Yes
Arabidopsis thaliana (thale-cress) (1)
Atha\ATO
9 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\PRP9
13 of 15
Yes
Yes
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\sap61
10 of 12
Yes
Yes
Spom\pcp1
1 of 12
No
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091906ZR )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00009207
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00010884
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00009209
Drosophila simulans
Dsim\GD19603
Drosophila sechellia
Dsec\GM10615
Drosophila sechellia
Dsec\GM15455
Drosophila erecta
Dere\GG10938
Drosophila yakuba
Dyak\GE24160
Drosophila ananassae
Dana\GF20764
Drosophila pseudoobscura pseudoobscura
Dpse\GA15523
Drosophila persimilis
Dper\GL21522
Drosophila willistoni
Dwil\GK22655
Drosophila virilis
Dvir\GJ24013
Drosophila mojavensis
Dmoj\GI23921
Drosophila grimshawi
Dgri\GH17377
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503R8 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17011498
Glossina morsitans
Tsetse fly
Gmor\GMOY011327
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_10782
Mayetiola destructor
Hessian fly
Mdes\Mdes009822
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL015244
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL012348
Anopheles darlingi
American malaria mosquito
Adar\ADAC001095
Anopheles gambiae
Malaria mosquito
Agam\AGAP003085
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ002728
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W03JE )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA006358
Danaus plexippus
Monarch butterfly
Dple\DPOGS207617-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL007862
Apis florea
Little honeybee
Aflo\2324838980
Apis mellifera
Western honey bee
Amel\SF3A3
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP14832
Bombus terrestris
Buff-tailed bumblebee
Bter\15205604
Linepithema humile
Argentine ant
Lhum\LH12891
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:002063
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007268
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_01699
Tribolium castaneum
Red flour beetle
Tcas\TC001034
Pediculus humanus
Human body louse
Phum\PHUM258680
Rhodnius prolixus
Kissing bug
Rpro\RPRC010937
Cimex lectularius
Bed bug
Clec\CLEC006021
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI000249
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_08506
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X03G1 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR007390
Ixodes scapularis
Black-legged tick
Isca\ISCW010835
Stegodyphus mimosarum
African social velvet spider
Smim\KFM83108.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur23g00810
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_216576
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G059G )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Sf3a3_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Sf3a3
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000002730
Gallus gallus
Domestic chicken
Ggal\SF3A3
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (1)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG5986
2 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    SF3A3; splicing factor 3a subunit 3
    15 of 15
    605596
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        esyN Network Diagram
        Show neighbor-neighbor interactions:
        Select Layout:
        Legend:
        Protein
        RNA
        Selected Interactor(s)
        Interactions Browser
        View in Interactions Browser
        Please see the Physical Interaction reports below for full details
        protein-protein
        Physical Interaction
        Assay
        References
        noi - Sf3a1
        experimental knowledge based
        (Guruharsha et al., 2011)
        noi - Sf3a2
        experimental knowledge based
        (Guruharsha et al., 2011)
        noi - Sf3b5
        anti tag coimmunoprecipitation, peptide massfingerprinting
        (Stegeman et al., 2016)
        noi - snf
        anti tag coimmunoprecipitation, peptide massfingerprinting
        (Stegeman et al., 2016)
        Summary of Genetic Interactions
        esyN Network Diagram
        esyN Network Key:
        Suppression
        Enhancement
        View in Interactions Browser
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        snf|Sxl
        enhanceable
        noi
        (Cline et al., 1999)
        Sxl|snf
        suppressible
        noi
        (Cline et al., 1999)
        External Data
        Subunit Structure (UniProtKB)
        Probable component of a the U2 small nuclear ribonucleoproteins complex (U2 snRNP).
        (UniProt, O46106 )
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        MIST (genetic) - An integrated Molecular Interaction Database
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        3R
        Recombination map

        3-47.5

        Cytogenetic map
        83B4-83B4
        Sequence location
        3R:5,589,601..5,591,459 [-]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        83B4-83B4
        Limits computationally determined from genome sequence between P{PZ}Snr101319&P{PZ}Itp-r83A05616 and P{lacW}Atus1938
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        83B1-83B2
        (determined by in situ hybridisation)
        (Spradling et al., 1999, BDGP Project Members, 1994-1999)
        83B-83B
        (determined by in situ hybridisation)
        (Meyer et al., 1998)
        Experimentally Determined Recombination Data
        Location

        3-47.5

        (FlyBase, 2016)

        3-44.1

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (7)
        Genomic Clones (10)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (36)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        Antibody Information
        Laboratory Generated Antibodies
         
        Commercially Available Antibodies
         
        Other Information
        Relationship to Other Genes
        Source for database identify of
        Source for database merge of

        Source for merge of: noi l(3)j3E7

        (Spradling et al., 1999)
        Additional comments
        Other Comments

        RNAi screen using dsRNA made from templates generated with primers directed against this gene results in a long metaphase spindle with misaligned chromosomes when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.

        (Goshima et al., 2007)

        Identified as a potential component of the hh signalling pathway in a genome-wide RNAi screen. dsRNA made from templates generated with primers directed affects the extent of expression of a hh signaling reporter construct in Clone 8 cells.

        (Nybakken et al., 2005)

        RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.

        (Boutros et al., 2004)

        Hypomorphic alleles reveal multiple roles of noi for the survival and differentiation of male germ cells, the differentiation of female germ cells and the development of several adult structures.

        (Meyer et al., 1998)

        Complete loss of noi function results in lethality at the end of embryogenesis, without obvious morphological defects.

        (Meyer et al., 1998)

        noi is required for the maintenance of the XY male germline stem cells and the few escaping germ cells fail to develop.

        (Pauli et al., 1995)
        Origin and Etymology
        Discoverer
        Etymology
        Identification
        External Crossreferences and Linkouts ( 43 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
        Other crossreferences
        BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        Flygut - An atlas of the Drosophila adult midgut
        GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
        InterPro - A database of protein families, domains and functional sites
        KEGG Genes - Molecular building blocks of life in the genomic space.
        modMine - A data warehouse for the modENCODE project
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DPiM - Drosophila Protein interaction map
        DroID - A comprehensive database of gene and protein interactions.
        DRSC - Results frm RNAi screens
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        FlyMine - An integrated database for Drosophila genomics
        InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
        KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
        MIST (genetic) - An integrated Molecular Interaction Database
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Synonyms and Secondary IDs (10)
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