SF3A3, l(3)j3E7
Please see the JBrowse view of Dmel\noi for information on other features
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Gene model reviewed during 5.48
There is only one protein coding transcript and one polypeptide associated with this gene
Probable component of a the U2 small nuclear ribonucleoproteins complex (U2 snRNP).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\noi using the Feature Mapper tool.
Comment: maternally deposited
GBrowse - Visual display of RNA-Seq signals
View Dmel\noi in GBrowse 23-47.5
3-47.5
3-44.1
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: noi l(3)j3E7
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in a long metaphase spindle with misaligned chromosomes when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Hypomorphic alleles reveal multiple roles of noi for the survival and differentiation of male germ cells, the differentiation of female germ cells and the development of several adult structures.
Complete loss of noi function results in lethality at the end of embryogenesis, without obvious morphological defects.
noi is required for the maintenance of the XY male germline stem cells and the few escaping germ cells fail to develop.