Scer\FRT-site insertion in third chromosome can influence second chromosome nondisjunction. The phenomenon demonstrates the behaviour of different pairs of homologous chromosomes in male meiosis are not independent.

The Scer\FLP1-Scer\FRT site-specific recombination system can be used to integrate DNA at a chromosomal Scer\FRT target site. Events are recovered using a w reporter gene.

The w^+mW.hs mutation carried in the P{FRT(w^hs)} element can be excised from its site of integration by the induction of Scer\FLP1 synthesis. Scer\FLP1 can be used to excise an Scer\FRT-flanked gene after cell division has ceased and the gene, now present on an extrachromosomal circle, is expressed. Most position effects are reverted by the removal of this gene from the chromosome.

The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(w^hs)} P{hsFLP} chromosomes) has been used to study the zygotic lethal mutation.

A method that uses Cbβ\DT-A, the Scer\FLP1 recognition target sequences and the Scer\GAL4-Scer\UAS activation system can be used to ablate specific neurons in the embryo and to examine the consequences.

Clonal analysis has been used to characterise the somatic stem cells that give rise to ovarian follicle cells.

Scer\FLP1 recombinase can promote mitotic exchange during embryonic development.