A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Scer\FLP1

General Information
SymbolScer\FLP1SpeciesS. cerevisiae
NameFLIP recombinaseAnnotation symbol
Feature typeengineered_foreign_geneFlyBase IDFBgn0014444
Gene Model StatusNot Applicable Stock availability 1513 publicly available
Also Known AsFLP
Genomic Location
Chromosome (arm)Recombination map
Cytogenetic mapSequence location
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Automatically generated summary

See sections below for more information
The gene FLIP recombinase is referred to in FlyBase by the symbol Scer\FLP1 (FBgn0014444). It is a engineered_foreign_gene from Saccharomyces cerevisiae. Its molecular function is unknown. The biological processes in which it is involved are not known. 60 alleles are reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.

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FB2013_03
Alleles
FB2013_02
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Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
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Allele of Scer\FLP1ClassMutagenStocksKnown lesion
Scer\FLP11231 --
Scer\FLP1173A1 --
Scer\FLP1232B1 --
Scer\FLP1276B1 --
Scer\FLP1291B1 --
Scer\FLP1398A1 --
Scer\FLP1467A1 --
Scer\FLP1525A1 --
Scer\FLP1820A1 --
Scer\FLP11143A0 --
Scer\FLP1247A0 --
Scer\FLP1250
0 --
Scer\FLP1420A0 --
Scer\FLP1505A0 --
Scer\FLP1567A0 --
Scer\FLP1570 --
Scer\FLP1757A0 --
Scer\FLP1fru0 Yes
hide Alleles Carried on Transgenic Constructs ( 43 )
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Allele of Scer\FLP1ClassMutagenStocksKnown lesion
Scer\FLP1ey.PN1347 Yes
Scer\FLP1hs.PG66 Yes
Scer\FLP1Scer\UAS.cDa40 Yes
Scer\FLP1Ubx.hs11 Yes
Scer\FLP1ET-FLPx29 Yes
Scer\FLP1hs.PP7 Yes
Scer\FLP1hs.PS7 Yes
Scer\FLP1ovo.PR4 Yes
Scer\FLP1Scer\UAS.Exel4 Yes
Scer\FLP15.hs2 Yes
Scer\FLP1ey.3.5.hs
2 Yes
Scer\FLP1ey.PB2 Yes
Scer\FLP1Ncra\QUAS.cPa2 Yes
Scer\FLP1Scer\UAS.cBb2 Yes
Scer\FLP1Scer\UAS.P\T.cGa2 Yes
Scer\FLP1ey.200.Exel1 Yes
Scer\FLP1ey.3.5.Exel1 Yes
Scer\FLP1ey.4x.Exel1 Yes
Scer\FLP1GMR.PP1 Yes
Scer\FLP1Ncra\QUAS.DSCP.cPa1 Yes
Scer\FLP1βTub85D.PS1 Yes
Scer\FLP15.ey0 Yes
Scer\FLP16.ey0 Yes
Scer\FLP17.ey0 Yes
Scer\FLP1D5.hs0 Yes
Scer\FLP1dac.3250 Yes
Scer\FLP1E(spl)mα-BFM.SOP0 Yes
Scer\FLP1EBD.Scer\UAS.T:Hsap\ESR10 Yes
Scer\FLP1en.PL0 Yes
Scer\FLP1eve.PR0 Yes
Scer\FLP1ey.PU0 Yes
Scer\FLP1G5.hs0 Yes
Scer\FLP1GH146.PP0 Yes
Scer\FLP1hs.P0 Yes
Scer\FLP1hs.PU0 Yes
Scer\FLP1L.8xEcol\lexAop0 Yes
Scer\FLP1m4.ey0 Yes
Scer\FLP1P\T.PL0 Yes
Scer\FLP1repo.PK0 Yes
Scer\FLP1Scer\UAS.cBa0 Yes
Scer\FLP1Scer\UAS.cCa0 Yes
Scer\FLP1Scer\UAS.cUa0 Yes
Scer\FLP1SOP.scE1x60 Yes
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hide OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
Drosophila inclusive ortholog search
No orthologs identified
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Ortholog(s) in Drosophila melanogaster (None identified)
No D. melanogaster orthologies identified
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hideAAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
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Bloomington
Kyoto
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Scer\FRT-site insertion in third chromosome can influence second chromosome nondisjunction. The phenomenon demonstrates the behaviour of different pairs of homologous chromosomes in male meiosis are not independent.
The Scer\FLP1-Scer\FRT site-specific recombination system can be used to integrate DNA at a chromosomal Scer\FRT target site. Events are recovered using a w reporter gene.
The w+mW.hs mutation carried in the P{FRT(whs)} element can be excised from its site of integration by the induction of Scer\FLP1 synthesis. Scer\FLP1 can be used to excise an Scer\FRT-flanked gene after cell division has ceased and the gene, now present on an extrachromosomal circle, is expressed. Most position effects are reverted by the removal of this gene from the chromosome.
The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to study the zygotic lethal mutation.
A method that uses Cbβ\DT-A, the Scer\FLP1 recognition target sequences and the Scer\GAL4-Scer\UAS activation system can be used to ablate specific neurons in the embryo and to examine the consequences.
Clonal analysis has been used to characterise the somatic stem cells that give rise to ovarian follicle cells.
Scer\FLP1 recombinase can promote mitotic exchange during embryonic development.
hide Tag or Foreign Gene Data
  • Foreign sequence; species == Saccharomyces cerevisiae; gene == FLP1; SGD:S000029654.
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SGD
  • S000029654
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hide Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym
FLIP
 
FLP
(Ratnakumar and Desplan, 2004.3, Clandinin et al., 2001, Maurel-Zaffran et al., 2001, Tanentzapf et al., 2000, Newsome et al., 2000, Maurel-Zaffran and Treisman, 2000, Luo et al., 1999, Percival-Smith and Bondy, 1999, Perrimon, 1998, Ahmad and Golic, 1998, Platero and Henikoff, 1998, Bellotto et al., 1998, Marin et al., 1998, Chen et al., 1998, Gorfinkiel et al., 1997, Yang et al., 1997, Mullor et al., 1997, Kosman and Small, 1997, Beumer, 1997.3.10, de Celis, 1997, Frise et al., 1996, Carroll et al., 2002, Lawrence et al., 2004, Djiane et al., 2005, Chew et al., 2004, Hofmeyer et al., 2006, LaLonde et al., 2006, Hiesinger et al., 2005, Bazigou et al., 2007, Komiyama et al., 2004, Bazigou et al., 2007, Kracklauer et al., 2007, Mehta et al., 2005, Wittwer et al., 2005, Thum et al., 2011, Molnar et al., 2011, Millard et al., 2007, Millard et al., 2007, Schimmelpfeng et al., 2006, Vaccari and Bilder, 2005, Wernet et al., 2006, Rakovitsky et al., 2007, Bhattacharya and Baker, 2009, Leismann and Lehner, 2003, Patel et al., 2009, Berger et al., 2008, Das Thakur et al., 2010, Potter et al., 2010, Grönke et al., 2010, Choi et al., 2009, Cheng et al., 2010, Song et al., 2007, Zhang et al., 2012, Poulton et al., 2011, Nern et al., 2011, Jenny, 2011, Awasaki et al., 2011, Awasaki et al., 2008, Roch et al., 2010, Elsaesser et al., 2010, Zheng et al., 2010, Tsuda et al., 2010, Herranz et al., 2010, Silicheva et al., 2010, Stephan et al., 2011, Leonardi et al., 2011, Moraru et al., 2012, Gault et al., 2012, Singh and Mlodzik, 2012, Hudson and Cooley, 2010, Haruta et al., 2010, Gurudatta et al., 2010)
Scer\FLP1
 
Name Synonym
FLIP recombinase
 
Secondary FlyBase IDs
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hide Recent research papers ( 37 )
Gault et al., 2012, J. Cell Biol. 196(5): 605--621
Drosophila CK1-γ, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking. [FBrf0217630]
Hong et al., 2012, Nature 484(7393): 201--207
Teneurins instruct synaptic partner matching in an olfactory map. [FBrf0218059]
Ji and Tulin, 2012, Nat. Commun. 3: 760
Poly(ADP-ribose) controls DE-cadherin-dependent stem cell maintenance and oocyte localization. [FBrf0217856]
Keleman et al., 2012, Nature 489(7414): 145--149
Dopamine neurons modulate pheromone responses in Drosophila courtship learning. [FBrf0219398]
Lai et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(7): 2607--2612
Auditory circuit in the Drosophila brain. [FBrf0217491]
Moraru et al., 2012, Neural Dev. 7(1): 14
Analysis of cell identity, morphology, apoptosis and mitotic activity in a primary neural cell culture system in Drosophila. [FBrf0218691]
Pan et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(25): 10065--10070
Joint control of Drosophila male courtship behavior by motion cues and activation of male-specific P1 neurons. [FBrf0218611]
Peng et al., 2012, Dev. Cell 23(3): 507--518
Planar Polarized Protrusions Break the Symmetry of EGFR Signaling during Drosophila Bract Cell Fate Induction. [FBrf0219458]
Pircs et al., 2012, PLoS ONE 7(8): e44214
Advantages and Limitations of Different p62-Based Assays for Estimating Autophagic Activity in Drosophila. [FBrf0219364]
Rezaval et al., 2012, Curr. Biol. 22(13): 1155--1165
Neural circuitry underlying Drosophila female postmating behavioral responses. [FBrf0218941]
Singh and Mlodzik, 2012, Dev. Cell 23(1): 82--96
Hibris, a Drosophila Nephrin Homolog, Is Required for Presenilin-Mediated Notch and APP-like Cleavages. [FBrf0218978]
Tanenhaus et al., 2012, PLoS ONE 7(10): e45130
In Vivo Circadian Oscillation of dCREB2 and NF-κB Activity in the Drosophila Nervous System. [FBrf0219734]
Xie et al., 2012, PLoS ONE 7(4): e36362
Uif, a Large Transmembrane Protein with EGF-Like Repeats, Can Antagonize Notch Signaling in Drosophila. [FBrf0218242]
Zhang et al., 2012, PLoS ONE 7(2): e31994
Control of tissue growth and cell transformation by the salvador/warts/hippo pathway. [FBrf0217552]
Charlton-Perkins et al., 2011, Neural Dev. 6: 20
Prospero and Pax2 combinatorially control neural cell fate decisions by modulating Ras- and Notch-dependent signaling. [FBrf0213993]
Gallio et al., 2011, Cell 144(4): 614--624
The coding of temperature in the Drosophila brain. [FBrf0213085]
Hadjieconomou et al., 2011, Nat. Methods 8(3): 260--266
Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster. [FBrf0213120]
Handler et al., 2011, EMBO J. 30(19): 3977--3993
A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. [FBrf0216344]
Hasegawa et al., 2011, Development 138(5): 983--993
Concentric zones, cell migration and neuronal circuits in the Drosophila visual center. [FBrf0213020]
Hatan et al., 2011, J. Cell Biol. 192(2): 307--319
The Drosophila blood brain barrier is maintained by GPCR-dependent dynamic actin structures. [FBrf0212807]
Hung et al., 2011, Science 334(6063): 1710--1713
Direct redox regulation of F-actin assembly and disassembly by Mical. [FBrf0217252]
Jenny, 2011, J. Vis. Exp.:
Preparation of Adult Drosophila Eyes for Thin Sectioning and Microscopic Analysis. [FBrf0215274]
Leonardi et al., 2011, Development 138(16): 3569--3578
Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling. [FBrf0214548]
Lin et al., 2011, Mol. Cell. Biol. 31(13): 2729--2741
A Barrier-Only Boundary Element Delimits the Formation of Facultative Heterochromatin in Drosophila melanogaster and Vertebrates. [FBrf0213867]
Matsubara et al., 2011, Genes Dev. 25(18): 1982--1996
The seven-pass transmembrane cadherin Flamingo controls dendritic self-avoidance via its binding to a LIM domain protein, Espinas, in Drosophila sensory neurons. [FBrf0215818]
Molnar et al., 2011, PLoS Genet. 7(3): e1001335
Role of the Drosophila non-visual ß-arrestin kurtz in hedgehog signalling. [FBrf0213301]
Nern et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(34): 14198--14203
Multiple new site-specific recombinases for use in manipulating animal genomes. [FBrf0214794]
Poulton et al., 2011, Development 138(9): 1737--1745
The microRNA pathway regulates the temporal pattern of Notch signaling in Drosophila follicle cells. [FBrf0213494]
Raghu and Borst, 2011, PLoS ONE 6(5): e19472
Candidate glutamatergic neurons in the visual system of Drosophila. [FBrf0213690]
Stephan et al., 2011, Mol. Biol. Cell 22(21): 4079--4092
Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila. [FBrf0216499]
Thum et al., 2011, J. Comp. Neurol. 519(17): 3415--3432
Diversity, variability, and suboesophageal connectivity of antennal lobe neurons in D. melanogaster larvae. [FBrf0216269]
Tong et al., 2011, Neuron 71(3): 447--459
Rich Regulates Target Specificity of Photoreceptor Cells and N-Cadherin Trafficking in the Drosophila Visual System via Rab6. [FBrf0214681]
Trivigno and Haerry, 2011, PLoS ONE 6(2): e16799
The Drosophila Mitochondrial Translation Elongation Factor G1 Contains a Nuclear Localization Signal and Inhibits Growth and DPP Signaling. [FBrf0213194]
Viktorin et al., 2011, Dev. Biol. 356(2): 553--565
Multipotent neural stem cells generate glial cells of the central complex through transit amplifying intermediate progenitors in Drosophila brain development. [FBrf0214495]
von Philipsborn et al., 2011, Neuron 69(3): 509--522
Neuronal control of Drosophila courtship song. [FBrf0212984]
Wang et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(27): 11139--11144
Sexually dimorphic regulation of the Wingless morphogen controls sex-specific segment number in Drosophila. [FBrf0214239]
Yuan et al., 2011, Science 333(6048): 1458--1462
Light-induced structural and functional plasticity in Drosophila larval visual system. [FBrf0215276]
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