FlyBase Gene Report: Scer\FLP1

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

engineered_foreign_gene

Stocks and Reagents

Stocks (3,755)

Bloomington

8862

P{hsFLP}22, w^*

6938

w¹¹¹⁸; P{70FLP}10

38882

w^*; P{ET-FLPx2}123

4540

w^*; P{UAS-FLP.D}JD2

5576

P{ey-FLP.N}5; ry⁵⁰⁶

5577

P{ey-FLP.N}6, ry⁵⁰⁶

8727

8729

38883

38886

108309

P{ey-FLP.N}5; ry⁵⁰⁶

108310

P{ey-FLP.N}6, ry⁵⁰⁶

More stocks available...

Other Comments

Scer\FRT-site insertion in third chromosome can influence second chromosome nondisjunction. The phenomenon demonstrates the behaviour of different pairs of homologous chromosomes in male meiosis are not independent.

(Fedorova and Omelyanchuk, 1997)

The Scer\FLP1-Scer\FRT site-specific recombination system can be used to integrate DNA at a chromosomal Scer\FRT target site. Events are recovered using a w reporter gene.

(Golic et al., 1997)

The w^+mW.hs mutation carried in the P{FRT(w^hs)} element can be excised from its site of integration by the induction of Scer\FLP1 synthesis. Scer\FLP1 can be used to excise an Scer\FRT-flanked gene after cell division has ceased and the gene, now present on an extrachromosomal circle, is expressed. Most position effects are reverted by the removal of this gene from the chromosome.

(Ahmad and Golic, 1996)

The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(w^hs)} P{hsFLP} chromosomes) has been used to study the zygotic lethal mutation.

(Perrimon et al., 1996)

A method that uses Cbβ\DT-A, the Scer\FLP1 recognition target sequences and the Scer\GAL4-Scer\UAS activation system can be used to ablate specific neurons in the embryo and to examine the consequences.

(Lin et al., 1995)

Clonal analysis has been used to characterise the somatic stem cells that give rise to ovarian follicle cells.

(Margolis and Spradling, 1995)

Scer\FLP1 recombinase can promote mitotic exchange during embryonic development.

(Dang and Perrimon, 1992)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (14)

Reported As

Symbol Synonym

FLIP

FLP

(Cook, 2017.12.20, Awasaki et al., 2014, Awasaki et al., 2014, Awasaki et al., 2014, Chen and Krasnow, 2014, Chen and Zipursky, 2014.4.17, Gambetta and Müller, 2014, Gurudev et al., 2014, Aoyama et al., 2013, Fregoso Lomas et al., 2013, Greer et al., 2013, Jukam et al., 2013, Rousso et al., 2013, Gault et al., 2012, Moraru et al., 2012, Singh and Mlodzik, 2012, Zhang et al., 2012, Awasaki et al., 2011, Jenny, 2011, Leonardi et al., 2011, Molnar et al., 2011, Nern et al., 2011, Poulton et al., 2011, Roy et al., 2011, Stephan et al., 2011, Thum et al., 2011, Biehs et al., 2010, Cheng et al., 2010, Das Thakur et al., 2010, Elsaesser et al., 2010, Erokhin et al., 2010, Grönke et al., 2010, Gurudatta et al., 2010, Haruta et al., 2010, Herranz et al., 2010, Hudson and Cooley, 2010, Krivega et al., 2010, Monastirioti et al., 2010, Portela et al., 2010, Potter et al., 2010, Richardson and Pichaud, 2010, Roch et al., 2010, Silicheva et al., 2010, Swaminathan and Pile, 2010, Tsuda et al., 2010, Zheng et al., 2010, Bhattacharya and Baker, 2009, Choi et al., 2009, Patel et al., 2009, Awasaki et al., 2008, Berger et al., 2008, Bazigou et al., 2007, Bazigou et al., 2007, Hattori et al., 2007, Kracklauer et al., 2007, Millard et al., 2007, Millard et al., 2007, Rakovitsky et al., 2007, Song et al., 2007, Hofmeyer et al., 2006, LaLonde et al., 2006, Schimmelpfeng et al., 2006, Wernet et al., 2006, Djiane et al., 2005, Hiesinger et al., 2005, Mehta et al., 2005, Vaccari and Bilder, 2005, Wittwer et al., 2005, Chew et al., 2004, Komiyama et al., 2004, Lawrence et al., 2004, Ratnakumar and Desplan, 2004.3, Leismann and Lehner, 2003, Carroll et al., 2002, Clandinin et al., 2001, Maurel-Zaffran et al., 2001, Maurel-Zaffran and Treisman, 2000, Newsome et al., 2000, Tanentzapf et al., 2000, Luo et al., 1999, Percival-Smith and Bondy, 1999, Ahmad and Golic, 1998, Bellotto et al., 1998, Chen et al., 1998, Marin et al., 1998, Perrimon, 1998, Platero and Henikoff, 1998, Beumer, 1997.3.10, de Celis, 1997, Gorfinkiel et al., 1997, Kosman and Small, 1997, Mullor et al., 1997, Yang et al., 1997, Chou and Perrimon, 1996, Frise et al., 1996)

FLP1

(Ji and Tulin, 2012, Roignant et al., 2010, Yamamoto-Hino et al., 2010)

Flp

(Domanitskaya et al., 2014, Pircs et al., 2012, Xie et al., 2012, Hadjieconomou et al., 2011, Handler et al., 2011, Biteau et al., 2010, Pataki et al., 2010, Sen et al., 2010, Tiefenböck et al., 2010, Herz et al., 2009, Spasić et al., 2008, Roy et al., 2007, Zhu et al., 2006, Emery et al., 2005, Hutterer and Knoblich, 2005, Komiyama et al., 2004, Campbell and Tomlinson, 1998, Chou and Perrimon, 1996)

Flp1

(Gunawan et al., 2013, Johnston et al., 1999)

Scer\FLP1

flip

(Peterson-Nedry et al., 2008)

Name Synonyms

FLIP recombinase

Flipase

(Trivigno and Haerry, 2011)

Flp DNA recombinase

(Busch and Tanimoto, 2010)

Flp recombinase

(Shirangi et al., 2013)

flipase

(Peterson-Nedry et al., 2008)

flippase

(Yuan et al., 2011)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 1 )

Other crossreferences

SGD - Saccharomyces Genome Database

S000029654

References (1,011)

Report Sections