FB2025_02 , released April 17, 2025
Gene: BacA\p35
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General Information
Symbol
BacA\p35
Species
N. Autographa californica nucleopolyhedrovirus
Name
Annotation Symbol
Feature Type
FlyBase ID
FBgn0014459
Gene Model Status
Stock Availability
Gene Summary
Contribute a Gene Snapshot for this gene.
Also Known As

p35

Foreign Gene Data

Foreign sequence; species == Baculovirus (Autographa californica); gene == 'p35'; UniProt:P08160.

Summaries
Alleles, Insertions, Transgenic Constructs
Classical and Insertion Alleles ( 0 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 18 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of BacA\p35
Transgenic constructs containing regulatory region of BacA\p35
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
glial cell | ectopic & antennal disc, with Scer\GAL4Dll-981
glial cell | ectopic & antennal disc, with Scer\GAL4lz-gal4
glial cell | ectopic & antennal disc, with Scer\GAL4pros.PMG
glial cell | ectopic | conditional ts & antennal disc, with Scer\GAL4hs.PB
macrochaeta | ectopic & scutellum, with Scer\GAL4pnr-MD237
macrochaeta | supernumerary & larva, with Scer\GAL4hs.PB
neuron & ventral nerve cord, with Scer\GAL4Crz.PC
Orthologs
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
Drosophila melanogaster (Fruit fly) (0)
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 5 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
Interaction Browsers

Please see the Physical Interaction reports below for full details
protein-protein
Physical Interaction
Assay
References
Summary of Genetic Interactions
Interaction Browsers
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
External Data
Linkouts
DroID - A comprehensive database of gene and protein interactions.
Class of Gene
Stocks and Reagents
Other Comments

Apoptosis of SL2 cells that is induced by expression of Cele\ced-3 or rpr can be prevented by expression of BacA\p35.

The eye phenotype of P{GMR-hid} individuals can be completely suppressed by coexpression of BacA\p35.

Expression of BacA\p35 eliminates most if not all normally occurring cell death in the developing D.melanogaster embryo and eye as well as X-irradiation-induced cell death.

Relationship to Other Genes
Source for database merge of
Additional comments
Nomenclature History
Source for database identify of
Nomenclature comments
Etymology
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
p35
(Dziedziech and Theopold, 2022, Hounsell and Fan, 2021, Ma et al., 2020, Wei et al., 2020, Zhuang et al., 2020, Harding and White, 2019, Hsieh et al., 2019, Kurmangaliyev et al., 2019, Rahmatika et al., 2019, Ramanathan et al., 2019, Sanchez et al., 2019, Wang et al., 2019, Yan et al., 2019, Akai et al., 2018, Campbell et al., 2018, Cong et al., 2018, Donohoe et al., 2018, Dewey and Johnston, 2017, He et al., 2017, Hong et al., 2017, Ibar and Glavic, 2017, Kamber Kaya et al., 2017, Liu et al., 2017, Lu et al., 2017, Pérez et al., 2017, Poulton et al., 2017, Recasens-Alvarez et al., 2017, Song et al., 2017, Teng et al., 2017, Tsuyama et al., 2017, Xie et al., 2017, Clemente-Ruiz et al., 2016, Kim et al., 2016, Li et al., 2016, Liu et al., 2016, Padash Barmchi et al., 2016, Akagawa et al., 2015, Dekanty et al., 2015, Hall and Verheyen, 2015, Kale et al., 2015, Martínez-Morentin et al., 2015, Bilak et al., 2014, Clemente-Ruiz et al., 2014, Eroglu et al., 2014, Fan et al., 2014, Homem et al., 2014, Kuang et al., 2014, Milet et al., 2014, Nakayama et al., 2014, Sen et al., 2014, Shimamura et al., 2014, Tanaka et al., 2014, Valzania et al., 2014, Wong et al., 2014, Yang et al., 2014, Chang et al., 2013, Das et al., 2013, Dichtel-Danjoy et al., 2013, Greer et al., 2013, Jagut et al., 2013, Karpac et al., 2013, Khan et al., 2013, Lee et al., 2013, Lin et al., 2013, Liu et al., 2013, Newquist et al., 2013, Newquist et al., 2013, Pechkovsky et al., 2013, Shen et al., 2013, Shin et al., 2013, Sutcliffe et al., 2013, Tang et al., 2013, Vanden Broeck et al., 2013, Yacobi-Sharon et al., 2013, Berger et al., 2012, Chinchore et al., 2012, Davidson and Duronio, 2012, Florentin and Arama, 2012, Ishida et al., 2012, Jones et al., 2012, Ma et al., 2012, Marchal et al., 2012, Reim et al., 2012, Schoenherr et al., 2012, Cranna et al., 2011, Estes et al., 2011, Guntermann and Foley, 2011, Kuranaga et al., 2011, Lee et al., 2011, Marinho et al., 2011, Oh and Irvine, 2011, Ouyang et al., 2011, Suissa et al., 2011, Tang et al., 2011, Ugrankar et al., 2011, Wang et al., 2011, Xin et al., 2011, Arya et al., 2010, Bakhrat et al., 2010, Batlevi et al., 2010, Bejarano et al., 2010, Benito-Sipos et al., 2010, Chakrabarti et al., 2010, Estella and Mann, 2010, Fan et al., 2010, Grant et al., 2010, Ismat et al., 2010, Kim et al., 2010, Kosmidis et al., 2010, Lam et al., 2010, Liu et al., 2010, Lopes and Casares, 2010, Losada-Pérez et al., 2010, Malzer et al., 2010, Mathur et al., 2010, Maurel-Zaffran et al., 2010, McPhee et al., 2010, Mesquita et al., 2010, Mitchell et al., 2010, Neto-Silva et al., 2010, Nojima et al., 2010, Padash-Barmchi et al., 2010, Portela et al., 2010, Rhiner et al., 2010, Roch et al., 2010, Rousset et al., 2010, Sandu et al., 2010, Schoenmann et al., 2010, Siekhaus et al., 2010, Suzanne et al., 2010, Umehara et al., 2010, Usha and Shashidhara, 2010, Warner et al., 2010, Yang et al., 2010, Glavic et al., 2009, Grieder et al., 2009, Lin et al., 2009, Mendes et al., 2009, Mohseni et al., 2009, Shen et al., 2009, Szuplewski et al., 2009, Tuxworth et al., 2009, Wang and Huang, 2009, Widmann and Dahmann, 2009, Wu et al., 2009, Bardet et al., 2008, Chen et al., 2008, Jaklevic et al., 2008, Jones et al., 2008, Joza et al., 2008, Lee et al., 2008, Park and Song, 2008, Protzer et al., 2008, Shapiro et al., 2008, Spasić et al., 2008, Toyama et al., 2008, Wang et al., 2008, Assa-Kunik et al., 2007, Bello et al., 2007, Berry and Baehrecke, 2007, Bidla et al., 2007, Chou et al., 2007, Gregory et al., 2007, Guan et al., 2007, Igaki et al., 2007, Karres et al., 2007, Kiger et al., 2007, Li and Baker, 2007, Mathieu et al., 2007, Pellock et al., 2007, Ryoo et al., 2007, Song et al., 2007, Sprecher et al., 2007, Srivastava et al., 2007, Steinhilb et al., 2007, Sugiyama et al., 2007, Baehrecke, 2006, Cela and Llimargas, 2006, Cho et al., 2006, Choi et al., 2006, Crickmore and Mann, 2006, Grosskortenhaus et al., 2006, Hamaratoglu et al., 2006, Han et al., 2006, Herranz et al., 2006, Huelsmann et al., 2006, Hyun et al., 2006, Jaekel and Klein, 2006, Leulier et al., 2006, Matova and Anderson, 2006, Mendes et al., 2006, Montell, 2006, Morris et al., 2006, Muro et al., 2006, Nolo et al., 2006, Oshima, 2006, Oshima et al., 2006, Parker, 2006, Pirraglia et al., 2006, Rives et al., 2006, Silva et al., 2006, Sprecher et al., 2006, Uhlirova and Bohmann, 2006, Verdier et al., 2006, Vrailas et al., 2006, Wichmann et al., 2006, Williams et al., 2006, Wood et al., 2006, Almeida and Bray, 2005, Bauer et al., 2005, Bauer et al., 2005, Cabernard and Affolter, 2005, Cenci and Gould, 2005, Coelho et al., 2005, McEwen and Peifer, 2005, Rogulja and Irvine, 2005, Sano et al., 2005, Thompson et al., 2005, Bruckner et al., 2004, Delanoue et al., 2004, Ghosh and Feany, 2004, Hsu et al., 2004, Otsuki et al., 2004, Punzo et al., 2004, Renault et al., 2004, Ryoo et al., 2004, Tsai and Sun, 2004, Bergmann et al., 2003, Giesen et al., 2003, Giraldez and Cohen, 2003, Heriche et al., 2003, Korey and MacDonald, 2003, Li et al., 2003, Udan et al., 2003, Hirose et al., 2001, Gaumer et al., 2000, Igaki et al., 2000, Cox et al., 1999, Migeon et al., 1999, Quinn et al., 1999, Renn et al., 1999, Staehling-Hampton et al., 1999, Ye and Fortini, 1999, Ahmed et al., 1998, Bose et al., 1998, Karim and Rubin, 1998, Namba and Minden, 1998, John and Brand, 1997)
Name Synonyms
baculovirus caspase inhibitor p35
Secondary FlyBase IDs
    Datasets (0)
    Study focus (0)
    Experimental Role
    Project
    Project Type
    Title
    Study result (0)
    Result
    Result Type
    Title
    External Crossreferences and Linkouts ( 1 )
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    References (936)