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Gene Dmel\gypsy\gag

General Information
Symbol	Dmel\gypsy\gag	Species	D. melanogaster
Name	gypsy element gag	Annotation symbol
Feature type	transposable_element_gene	FlyBase ID	FBgn0014965
Gene Model Status	Not Applicable	Stock availability	None publicly available
Also Known As	GAG, ORF1
Genomic Location
Chromosome (arm)		Recombination map
Cytogenetic map		Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene gypsy element gag is referred to in FlyBase by the symbol gypsy\gag (FBgn0014965). It is a transposable_element_gene from gypsy element (D. melanogaster). It is encoded by the gypsy transposable element. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AF033821 AAC82603   M12927 AAA70218
UniProtKB/Swiss-Prot	P10405
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of gypsy\gag Class Mutagen Stocks Known lesion gypsy\gagSS natural population 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of gypsy\gag Class Mutagen Stocks Known lesion gypsy\gag111fs3 in vitro construct 0 Yes gypsy\gag6Kfs1 in vitro construct 0 Yes gypsy\gag6Kfs3 in vitro construct 0 Yes gypsy\gagScer\UAS.hs in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data characterization construct P{gypsy6Kfs1} NA P{gypsy6Kfs3} NA P{gypsy111fs3} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	transposable_element_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions gypsy\gag allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Encoded by	gypsy
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	DDBJ / EMBL / GenBank • AAA70218 AAC82603 AF033821 M12927 UniProtKB/Swiss-Prot • P10405
Other Crossreferences
Linkouts
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	GAG (Labrador and Corces, 1999, Antao et al., 2012) gag (Gabus et al., 2006, Malik and Henikoff, 2005, Terzian et al., 2001) Gag (Syomin and Ilyin, 2006) gypsy\gag   ORF1 (Smith and Cronmiller, 2001, Lyubomirskaya et al., 2001, Alberola and de Frutos, 1996, Avedisov and Ilyin, 1994, )
Name Synonym	gypsy element gag
Secondary FlyBase IDs
References ( 16 )
Research paper	Antao et al., 2012, Mol. Cell. Biol. 32(12): 2170--2182 Protein Landscape at Drosophila melanogaster Telomere-Associated Sequence Repeats. [FBrf0218429] Gabus et al., 2006, Nucleic Acids Res. 34(20): 5764--5777 Characterization of a nucleocapsid-like region and of two distinct primer tRNALys,2 binding sites in the endogenous retrovirus Gypsy. [FBrf0194191] Syomin and Ilyin, 2006, Dokl. Biochem. Biophys. 408: 120--122 Detection of the structural protein, Gag, of the endogenous insect retrovirus MDG4 (gypsy) in cultured cells. [FBrf0193991] Malik and Henikoff, 2005, PLoS Genet. 1(4): e44 Positive selection of Iris, a retroviral envelope-derived host gene in Drosophila melanogaster. [FBrf0191390] Labrador and Corces, 2003, Genes Dev. 17(1): 43--48 Phosphorylation of histone H3 during transcriptional activation depends on promoter structure. [FBrf0155495] Lyubomirskaya et al., 2001, Mol. Genet. Genomics 265(2): 367--374 Two variants of the Drosophila melanogaster retrotransposon gypsy (mdg4): structural and functional differences, and distribution in fly stocks. [FBrf0137025] Smith and Cronmiller, 2001, Development 128(23): 4705--4714 The Drosophila daughterless gene autoregulates and is controlled by both positive and negative cis regulation. [FBrf0141491] Terzian et al., 2001, BMC Evol. Biol. 1(1): 3 Evolution and phylogeny of insect endogenous retroviruses. [FBrf0139592] Chalvet et al., 1999, EMBO J. 18(9): 2659--2669 Proviral amplification of the gypsy endogenous retrovirus of Drosophila melanogaster involves env-independent invasion of the female germline. [FBrf0108442] Petropoulos, 1997, Coffin, Hughes, Varmus, 1997: 757 Retroviral taxonomy, protein structures, sequences, and genetic maps. [FBrf0137152] Alberola and de Frutos, 1996, Nucleic Acids Res. 24(5): 914--923 Molecular structure of a gypsy element of Drosophila subobscura (gypsyDs) constituting a degenerate form of insect retroviruses. [FBrf0086305] Avedisov and Ilyin, 1994, FEBS Lett. 350(1): 147--150 Identification of spliced RNA species of Drosophila melanogaster gypsy retrotransposon: New evidence for retroviral nature of the gypsy element. [FBrf0076478] Song et al., 1994, Genes Dev. 8(17): 2046--2057 An env-like protein encoded by a Drosophila retroelement: evidence that gypsy is an infectious retrovirus. [FBrf0076503]
Review	Wright and Finnegan, 2001, Curr. Biol. 11(8): R296--R299 Genome evolution: sex and the transposable element. [FBrf0136840]
Abstract	Labrador and Corces, 1999, A. Dros. Res. Conf. 40: 665A Ectopic expression of a gypsy retrovirus during Drosophila development leads to lethality or severe abnormalities in the adult abdominal cuticle. [FBrf0106806] Alberola and de Frutos, 1995, Europ. Dros. Res. Conf. 14: 187 The Drosophila subobscura gypsy element constitutes a degenerate form of insect retroviruses. [FBrf0082999]