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Gene Dmel\Ssl

General Information
Symbol	Dmel\Ssl	Species	D. melanogaster
Name	Suppressor of Stellate-like	Annotation symbol	CG13591
Feature type	protein_coding_gene	FlyBase ID	FBgn0015300
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	βCK2tes, CK2βtes
Genomic Location
Chromosome (arm)	2R	Recombination map	2-
Cytogenetic map	60D1-60D1	Sequence location	2R:20,386,766..20,387,754 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Suppressor of Stellate-like is referred to in FlyBase by the symbol Dmel\Ssl (CG13591, FBgn0015300). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein kinase regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process: protein phosphorylation. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Casein kinase II, regulatory subunit; Casein kinase II, regulatory subunit, alpha-helical; Casein kinase II, regulatory subunit, beta-sheet. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1641012_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Ssl. Gene sequence location is 2R:20386766..20387754.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN51267 BKN50591 BKN25632 HFA04657
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 60D1-60D1   Limits computationally determined from genome sequence between P{PZ}bs03267&P{lacW}l(2)k10502k10502 and P{lacW}Nurf-38k16102
Experimentally Determined Cytological Location
Cytogenetic map Notes References 60B-60C     (Kalmykova, 1995) 60D1-60D2   (determined by in situ hybridisation)   (Kalmykova et al., 1997)
Experimentally Determined Recombination Data
Location	2- (Kalmykova, 1995) 1- (Kalmykova, 1995)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Ssl for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ssl-RA FBtr0072351  NM_079124   872   219
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ssl-PA   FBpp0072258   25.2   219   6.24     NP_523848   AAF47214
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Casein kinase II, regulatory subunit (IPR000704) Casein kinase II, regulatory subunit, alpha-helical (IPR016149) Casein kinase II, regulatory subunit, beta-sheet (IPR016150)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF47214   AI946728   AY089437 AAL90175   BF489436   CO300362   EC222861   L42285 AAB65818   L49382 AAB65817
UniProtKB/Swiss-Prot	Q24536
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0015300    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0015300 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0015300 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day    1686 adult male 30day    1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2  (250) larva L3 puffstage 3-6  (462) larva L3 puffstage 7-9  (480) white prepupae new  (509) white prepupae 12hr  (791) white prepupae 24hr  (1036) pupae 2d postWPP  (1126) pupae 3d postWPP  (786) pupae 4d postWPP  (619) adult male 01day  (990) adult male 05day  (1686) adult male 30day  (1418) adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day  (1686) adult male 30day  1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day    1686 adult male 30day    1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day    1686 adult male 30day    1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0015300 expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day    1686 adult male 30day    1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2  (250) larva L3 puffstage 3-6  (462) larva L3 puffstage 7-9  (480) white prepupae new  (509) white prepupae 12hr  (791) white prepupae 24hr  (1036) pupae 2d postWPP  (1126) pupae 3d postWPP  (786) pupae 4d postWPP  (619) adult male 01day  (990) adult male 05day  (1686) adult male 30day  (1418) adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day  1686 adult male 30day  1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day    1686 adult male 30day    1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    9 larva L2    0 larva L3 12hr old    24 larva L3 puffstage 1-2    250 larva L3 puffstage 3-6    462 larva L3 puffstage 7-9    480 white prepupae new    509 white prepupae 12hr    791 white prepupae 24hr    1036 pupae 2d postWPP    1126 pupae 3d postWPP    786 pupae 4d postWPP    619 adult male 01day    990 adult male 05day    1686 adult male 30day    1418 adult female 01day    6 adult female 05day    0 adult female 30day    4 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0015300    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0015300 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0015300 expression level Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0015300 expression level Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.35 Larval Midgut    2.7 Larval Hindgut    2.4 Larval Malpighian Tubules    2.8 Larval Fat Body no informative data Larval Salivary Gland    2.1 Larval Trachea    4.125 Larval Carcass    2.4 Adult Head    3.8 Adult Eye    2.525 Adult Brain    2.2 Adult Thoracic-Abdominal Ganglion    4.1 Adult Crop    5.9 Adult Midgut    3.8 Adult Hindgut    4.5 Adult Malpighian Tubules    5 Adult Fat Body    5.7 Adult Salivary Gland    3.2 Adult Heart    2.65 Adult VirginFemale Spermatheca    3.4 Adult InseminatedFemale Spermatheca    4.6 Adult Ovary    1 Adult Testis    418.5 Adult Male Accessory Gland no informative data Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body no informative data Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland no informative data Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    3.8   NA  Eye    2.525   NA  Brain    2.2   3.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    4.1   NA  Crop    5.9   2.7  Midgut    3.8   2.4  Hindgut    4.5   2.8  Malpighian Tubules    5   no informative data  Fat Body    5.7   2.1  Salivary Gland    3.2   NA  Heart    2.65   4.125  Trachea    NA   NA  VirginFemale Spermatheca    3.4   NA  InseminatedFemale Spermatheca    4.6   NA  Ovary    1   NA  Testis    418.5   NA  Male Accessory Gland    no informative data   2.4  Carcass    3.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015300 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13591-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4αTub84B.PL SslScer\UAS.cJa viable, with Scer\GAL4pnr-MD237 SslGD8064 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Ssl Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ssl Class Mutagen Stocks Known lesion SslGD8064 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes SslKK104672 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Ssl173.T:Ecol\lacZ in vitro construct - coding region fusion 0 Yes Ssl934.T:Ecol\lacZ in vitro construct - coding region fusion 0 Yes Ssla.βTub85D in vitro construct - regulatory fusion 0 Yes SslScer\UAS.cJa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel6278 (Ryder, 2004.4.26) Df(2R)Exel7185 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data reporter construct P{Ssl-lacZ.173} No P{Ssl-lacZ.934} No UAS construct P{GD8064} NA P{KK104672} NA P{UAS-Ssl.J} NA characterization construct P{βTub85D-Ssl.a} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function
CV term Evidence References
protein kinase regulator activity inferred from direct assay (Kalmykova et al., 2002)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
protein kinase activity non-traceable author statement (Morrison et al., 2000) protein serine/threonine kinase activity inferred from sequence or structural similarity (Kalmykova et al., 1997) inferred from sequence or structural similarity with Saccharomyces CKB2 (FlyBase, 1992-) non-traceable author statement (Kalmykova, 1995, Swiss-Prot Project Members, 1998.4.15)
Biological Process
CV term Evidence References
protein phosphorylation inferred from sequence or structural similarity (Kalmykova et al., 1997) non-traceable author statement (Morrison et al., 2000)
Cellular Component
CV term Evidence References
protein kinase CK2 complex inferred from electronic annotation with InterPro:IPR000704, InterPro:IPR016149, InterPro:IPR016150 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ssl allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0015300 DroID - A comprehensive database of gene and protein interactions. • FBgn0015300 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37909
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11247 Dere\GG19923 Dgri\GH22749 Dper\GL20424 Dpse\GA25112 Dsec\GM11826 Dsim\GD24508 Dwil\GK19682 Dyak\GE11447
Curated drosophilid orthologs	Dpse\GA12385
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0229252 FBgn0221680 FBgn0208525 FBgn0207846 FBgn0195845 FBgn0195843 FBgn0192312 FBgn0187515 FBgn0172478 FBgn0172465 FBgn0172463 FBgn0172464 FBgn0172460 FBgn0166767 FBgn0246495 FBgn0158019 FBgn0143723 FBgn0141271 FBgn0130206 FBgn0112123 FBgn0088287
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v108692 P{KK104672}VIE-260B v17282 w1118; P{GD8064}v17282 v17280 w1118; P{GD8064}v17280/CyO
Genomic Clones ( 2 )
	BACR02A05 BACR11C07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 5 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT25555
Other clones	DPiM_AT25555
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	53942 bs30a09 EK178031
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0015300 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37909
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Ssl NEST:bs30a09 (Rana, 2004.7.8)
Additional comments
Other Comments
	Ssl is in a regulated chromatin domain that includes testes-specific genes. (Kalmykova et al., 2005) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Molecular characterisation of a euchromatic gene. Ssl is derived from CkIIβ gene by reverse transcriptase. This event resulted in the loss of the first three introns in the coding region of the ancestor gene. Since this event Ssl has evolved under selective pressure at the transcriptional level. (Kalmykova et al., 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079124 RefSeq (Proteins) • NP_523848 DDBJ / EMBL / GenBank • AAB65817 AAB65818 AAF47214 AAL90175 AI946728 AY089437 BF489436 L42285 L49382 Entrez Gene - A searchable database of RefSeq genes. • 37909 UniProtKB/Swiss-Prot • Q24536
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Casein kinase II, regulatory subunit (IPR000704) Casein kinase II, regulatory subunit, alpha-helical (IPR016149) Casein kinase II, regulatory subunit, beta-sheet (IPR016150)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0015300 DroID - A comprehensive database of gene and protein interactions. • FBgn0015300 DRSC - Results from RNAi screens. • FBgn0015300 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015300 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG13591-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0015300 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 37909 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 37909 modMine - Data generated by the modENCODE project. • FBgn0015300 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0229252 FBgn0221680 FBgn0208525 FBgn0207846 FBgn0195845 FBgn0195843 FBgn0192312 FBgn0187515 FBgn0172478 FBgn0172465 FBgn0172463 FBgn0172464 FBgn0172460 FBgn0166767 FBgn0246495 FBgn0158019 FBgn0143723 FBgn0141271 FBgn0130206 FBgn0112123 FBgn0088287
Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	CG13591 (Morrison et al., 2000, Keleman et al., 2009.8.5) CK2βtes (Boutanaev et al., 2002, Kalmykova et al., 2002, Jauch et al., 2006, Kalmykova et al., 2005) CKIIb1 (Morrison et al., 2000) DmCK2βtes (Mentzel et al., 2009) NEST:bs30a09   SSL (Kalmykova, 1995, Kalmykova, 1995, Kalmykova et al., 1997, Kalmykova et al., 1997) Ssl (Mikhaylova et al., 2006, Kalmykova et al., 2005, Shevelyov et al., 2009, Aoyagi and Wassarman, 2001) Su(Ste)l   βCK2tes (Gvozdev et al., 2000, Polesskaya et al., 1999, Kalmykova et al., 1997, Gvozdev et al., 2005, Usakin et al., 2005)
Name Synonym	regulatory subunit of protein kinase CK2 (Gvozdev et al., 2005) Su(Ste)-like (Kalmykova et al., 1997) Suppressor of Stellate-like
Secondary FlyBase IDs
	FBgn0014036 FBgn0045134
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 13 ) Supplementary material  ( 3 ) Review  ( 2 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 2 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 2 ) Protein sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...