A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Hsap\T:Hsap\MYC

General Information
SymbolHsap\T:Hsap\MYCSpeciesH. sapiens
NameAnnotation symbol
Feature typeengineered_foreign_regionFlyBase IDFBgn0015310
Gene Model StatusNot Applicable Stock availability None publicly available
Genomic Location
Chromosome (arm)Recombination map
Cytogenetic mapSequence location
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Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol T:Hsap\MYC (FBgn0015310). It is a engineered_foreign_region from T:Hsap. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has no annotated transcripts. Gene has not been localized to the genome sequence.
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Description
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FB2013_03
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Evidence for location
Experimentally Determined Cytological Location
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Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
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Annotated Transcripts
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FlyBase ID
RefSeq ID
Length (nt)
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Annotated Polypeptides
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Length (aa)
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DDBJ /
EMBL /
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DNA sequence
Protein sequence
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Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
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Phenotype manifest in
Allele
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Allele of T:Hsap\MYCClassMutagenStocksKnown lesion
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Allele of T:Hsap\MYCClassMutagenStocksKnown lesion
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Transgenic Constructs
Type of construct
Name
Expression data
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Type of insertions
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Expression data
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Interacts with
Please look at the allele data for full details of the genetic interactions
T:Hsap\MYC allele
Gene
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hide OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
Drosophila inclusive ortholog search
No orthologs identified
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Ortholog(s) in Drosophila melanogaster (None identified)
No D. melanogaster orthologies identified
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Gene
OMIM
HGNC
hideAAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
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Source for database merge of
Tags
(Boyle et al., 1997, van de Wetering et al., 1997, Pai et al., 1997, Hacker et al., 1997, O'Keefe et al., 1997, Cadigan et al., 1998, Steitz et al., 1998, Gallet et al., 1998, Axelrod et al., 1998, Bilder and Scott, 1998, Yu et al., 1998, Von Ohlen and Hooper, 1999, Gallet et al., 1999, Garcia-Garcia et al., 1999, Kopp et al., 1999, Payre et al., 1999, Cox et al., 1999, Gritzan et al., 1999, Alexandre et al., 1999, Erkner et al., 1999, Helms et al., 1999, Yu et al., 1999, Brennan et al., 1999, Buratovich et al., 2000, Zeng et al., 2000, McEwen et al., 2000, Hatini et al., 2000, Chihara and Hayashi, 2000, Llimargas, 2000, Yang et al., 2000, Baeg et al., 2001, Halfon et al., 2000, San Martin and Bate, 2001, Waltzer et al., 2001, Freeman and Bienz, 2001, Verheyen et al., 2001, Takashima and Murakami, 2001, Hatini and DiNardo, 2001, Rousset et al., 2001, Tolwinski and Wieschaus, 2001, Loureiro et al., 2001, Boube et al., 2001, Marty et al., 2001, Sudarsan et al., 2001, Angelats et al., 2002, Llimargas and Lawrence, 2001, Streit et al., 2002, Yang et al., 2002, Price and Kalderon, 2002, Kramps et al., 2002, Giraldez et al., 2002, Thompson et al., 2002, Jackson et al., 2002, Buratovich and Wilder, 2001, Glise et al., 2002, Inaki et al., 2002, Wu and Cohen, 2002, Akong et al., 2002, Adachi-Yamada and O'Connor, 2002, Cadigan et al., 2002, Ponzielli et al., 2002, Alexandre and Vincent, 2003, Kaltschmidt et al., 2002, Kubota et al., 2003, Tolwinski et al., 2003, Prasad et al., 2003, Song and Xie, 2003, Wernet et al., 2003, Larsen et al., 2003, Yan et al., 2004, Brumby and Richardson, 2003, Moreno and Basler, 2004, Thompson, 2004, Bajpai et al., 2004, Tolwinski and Wieschaus, 2004, Morel and Arias, 2004, Kouzmenko et al., 2004, Hoffmans and Basler, 2004, Han et al., 2005, Cox and Baylies, 2005, Hatini et al., 2005, Hoffmans et al., 2005, Piddini et al., 2005, Mueller et al., 2005)
Additional comments
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The T:Hsap\MYC epitope tag is recognised by a mouse monoclonal antibody (monoclonal 9E10 - BAbCo) raised against a synthetic peptide comprising residues 409-439 of human MYC.
 
hide Tag or Foreign Gene Data
  • Foreign sequence; species == Homo sapiens; epitope tag == 'EQKLISEEDL' {Homo sapiens MYC protein, residues 409-439}.
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hide Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym
Myc
 
T:Hsap\MYC
 
T:Myc
 
Name Synonym
Secondary FlyBase IDs
  • FBgn0016746
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hide Recent research papers ( 72 )
Bharadwaj et al., 2013, Development 140(3): 627--638
Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. [FBrf0220383]
Althoff et al., 2012, Mol. Biol. Cell 23(12): 2275--2291
Spindle checkpoint-independent inhibition of mitotic chromosome segregation by Drosophila Mps1. [FBrf0218626]
Anand and Kai, 2012, EMBO J. 31(4): 870--882
The tudor domain protein Kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila. [FBrf0217541]
Beck et al., 2012, J. Neurosci. 32(20): 7058--7073
Regulation of Fasciclin II and Synaptic Terminal Development by the Splicing Factor Beag. [FBrf0218385]
Carroll et al., 2012, Development 139(3): 612--621
The extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation. [FBrf0217120]
Chau et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(24): 9465--9470
Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis. [FBrf0218549]
Chen et al., 2012, EMBO J. 31(12): 2798--2809
Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene. [FBrf0218712]
Coffee et al., 2012, Hum. Mol. Genet. 21(4): 900--915
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. [FBrf0217253]
Deluca and O'Farrell, 2012, Dev. Cell 22(3): 660--668
Barriers to male transmission of mitochondrial DNA in sperm development. [FBrf0217815]
Dodson et al., 2012, Hum. Mol. Genet. 21(6): 1350--1363
Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning. [FBrf0217544]
Dottermusch-Heidel et al., 2012, Dev. Biol. 368(1): 18--27
The Arf-GEF Schizo/Loner regulates N-cadherin to induce fusion competence of Drosophila myoblasts. [FBrf0218661]
Enjolras et al., 2012, J. Cell Biol. 197(2): 313--325
Drosophila chibby is required for basal body formation and ciliogenesis but not for Wg signaling. [FBrf0218054]
Fan et al., 2012, Dev. Biol. 366(2): 172--184
Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner. [FBrf0218374]
Gault et al., 2012, J. Cell Biol. 196(5): 605--621
Drosophila CK1-γ, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking. [FBrf0217630]
Grima et al., 2012, PLoS Biol. 10(8): e1001367
CULLIN-3 Controls TIMELESS Oscillations in the Drosophila Circadian Clock. [FBrf0219137]
Grönholm et al., 2012, FASEB J. 26(3): 1239--1250
Not4 enhances JAK/STAT pathway-dependent gene expression in Drosophila and in human cells. [FBrf0217636]
Guilgur et al., 2012, Development 139(3): 503--513
Drosophila aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells. [FBrf0217157]
Haskel-Ittah et al., 2012, Cell 150(5): 1016--1028
Self-organized shuttling: generating sharp dorsoventral polarity in the early Drosophila embryo. [FBrf0219335]
Herrera-Cruz et al., 2012, J. Biol. Chem. 287(40): 33567--33580
Physical and Functional Interactions between Drosophila Homologue of Swc6/p18Hamlet Subunit of the SWR1/SRCAP Chromatin-remodeling Complex with the DNA Repair/Transcription Factor TFIIH. [FBrf0219503]
Jeong et al., 2012, Neuron 76(4): 721--734
The Control of Semaphorin-1a-Mediated Reverse Signaling by Opposing Pebble and RhoGAPp190 Functions in Drosophila. [FBrf0219982]
Jones et al., 2012, Cell. Microbiol. 14(2): 274--285
Aeromonas salmonicida-secreted protein AopP is a potent inducer of apoptosis in a mammalian and a Drosophila model. [FBrf0217270]
Lee and Fischer, 2012, PLoS ONE 7(9): e46357
Drosophila Tel2 Is Expressed as a Translational Fusion with EpsinR and Is a Regulator of Wingless Signaling. [FBrf0219532]
Mann et al., 2012, Development 139(4): 760--771
A putative tyrosine phosphorylation site of the cell surface receptor Golden goal is involved in synaptic layer selection in the visual system. [FBrf0217291]
Rudolf et al., 2012, Europ. J. Cell Biol. 91(3): 192--203
The syncytial visceral and somatic musculature develops independently of β3-Tubulin during Drosophila embryogenesis, while maternally supplied β1-Tubulin is stable until the early steps of myoblast fusion. [FBrf0217503]
Schaub et al., 2012, Development 139(5): 1001--1012
Org-1, the Drosophila ortholog of Tbx1, is a direct activator of known identity genes during muscle specification. [FBrf0217455]
Stochmanski et al., 2012, Hum. Mol. Genet. 21(10): 2211--2218
Expanded ATXN3 frameshifting events are toxic in Drosophila and mammalian neuron models. [FBrf0218121]
Tangredi et al., 2012, J. Biol. Chem. 287(20): 16748--16758
The C-terminal Kinase and ERK-binding Domains of Drosophila S6KII (RSK) Are Required for Phosphorylation of the Protein and Modulation of Circadian Behavior. [FBrf0218308]
Troost et al., 2012, J. Cell Sci. 125(3): 763--776
The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4. [FBrf0217584]
Turki-Judeh and Courey, 2012, PLoS ONE 7(2): e30610
The unconserved groucho central region is essential for viability and modulates target gene specificity. [FBrf0217447]
Wang et al., 2012, J. Neurosci. 32(10): 3485--3491
The Drosophila Visual Cycle and De Novo Chromophore Synthesis Depends on rdhB. [FBrf0217693]
Wang et al., 2012, Mol. Cell. Biol. 32(12): 2203--2213
LST8 Regulates Cell Growth via Target-of-Rapamycin Complex 2 (TORC2). [FBrf0218417]
Wong et al., 2012, Curr. Biol. 22(17): 1616--1621
Drosophila TRPML Is Required for TORC1 Activation. [FBrf0219457]
Xia et al., 2012, PLoS Biol. 10(1): e1001238
USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization. [FBrf0218247]
Xia et al., 2012, Mol. Neurodegener. 7: 10
Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS. [FBrf0218020]
Xiao et al., 2012, Development 139(15): 2670--2680
klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division. [FBrf0218804]
Yamamoto-Hino et al., 2012, Cell Struct. Funct. 37(1): 55--63
Cisterna-specific Localization of Glycosylation-related Proteins to the Golgi Apparatus. [FBrf0217862]
Yoshiura et al., 2012, Dev. Cell 22(1): 79--91
Tre1 GPCR Signaling Orients Stem Cell Divisions in the Drosophila Central Nervous System. [FBrf0217269]
Yue et al., 2012, Dev. Cell 22(2): 255--267
The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the hippo signaling pathway. [FBrf0217474]
Zhan et al., 2012, Mol. Biol. Evol. 29(5): 1407--1416
Rapid Functional Divergence of a Newly Evolved Polyubiquitin Gene in Drosophila and Its Role in the Trade-off between Male Fecundity and Lifespan. [FBrf0218166]
Abou Tayoun et al., 2011, J. Neurosci. 31(39): 13897--13910
The Drosophila SK Channel (dSK) Contributes to Photoreceptor Performance by Mediating Sensitivity Control at the First Visual Network. [FBrf0216279]
Akbar et al., 2011, J. Cell Biol. 192(3): 383--390
The full-of-bacteria gene is required for phagosome maturation during immune defense in Drosophila. [FBrf0212933]
Akhouayri et al., 2011, PLoS Pathog. 7(10): e1002319
Toll-8/tollo negatively regulates antimicrobial response in the Drosophila respiratory epithelium. [FBrf0216452]
Banerjee et al., 2011, PLoS ONE 6(10): e25926
A Laminin G-EGF-Laminin G module in Neurexin IV is essential for the apico-lateral localization of Contactin and organization of septate junctions. [FBrf0217685]
Burnett et al., 2011, Nature 477(7365): 482--485
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. [FBrf0215823]
Cao et al., 2011, EMBO J. 30(18): 3701--3713
A Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin. [FBrf0215269]
Choi et al., 2011, J. Biol. Chem. 286(4): 2658--2664
Drosophila Salt-inducible Kinase (SIK) Regulates Starvation Resistance through cAMP-response Element-binding Protein (CREB)-regulated Transcription Coactivator (CRTC). [FBrf0212827]
Gradilla et al., 2011, Genetics 189(3): 871--883
Isoform-Specific Regulation of a Steroid Hormone Nuclear Receptor by an E3 Ubiquitin Ligase in Drosophila melanogaster. [FBrf0216551]
Hampel et al., 2011, Nat. Methods 8(3): 253--259
Drosophila Brainbow: a recombinase-based fluorescence labeling technique to subdivide neural expression patterns. [FBrf0213136]
Johnson et al., 2011, Mol. Biol. Cell 22(23): 4513--4526
Role for a Cindr-Arf6 axis in patterning emerging epithelia. [FBrf0216708]
Keene et al., 2011, J. Neurosci. 31(17): 6527--6534
Distinct visual pathways mediate Drosophila larval light avoidance and circadian clock entrainment. [FBrf0213587]
Kim et al., 2011, BMC Physiol. 11: 7
Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness. [FBrf0213903]
Lawlor et al., 2011, Hum. Mol. Genet. 20(19): 3757--3768
Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases. [FBrf0215240]
Layalle et al., 2011, Development 138(11): 2315--2323
Engrailed homeoprotein acts as a signaling molecule in the developing fly. [FBrf0213689]
Lelli et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(52): 21122--21127
Variable motif utilization in homeotic selector (Hox)-cofactor complex formation controls specificity. [FBrf0217107]
Luo et al., 2011, Development 138(13): 2761--2771
Direct targets of the D. melanogaster DSXF protein and the evolution of sexual development. [FBrf0213878]
Noro et al., 2011, Genes Dev. 25(22): 2327--2332
Competition for cofactor-dependent DNA binding underlies Hox phenotypic suppression. [FBrf0216806]
Ohler et al., 2011, Dev. Dyn. 240(1): 135--148
Hts, the Drosophila homologue of adducin, physically interacts with the transmembrane receptor golden goal to guide photoreceptor axons. [FBrf0212583]
Petersen and Stowers, 2011, PLoS ONE 6(9): e24531
A Gateway MultiSite Recombination Cloning Toolkit. [FBrf0215584]
Tian et al., 2011, Nat. Neurosci. 14(10): 1267--1275
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons. [FBrf0216253]
Tomita et al., 2011, J. Neurosci. 31(37): 13137--13146
Pan-Neuronal Knockdown of Calcineurin Reduces Sleep in the Fruit Fly, Drosophila melanogaster. [FBrf0215571]
van Eyk et al., 2011, Hum. Mol. Genet. 20(14): 2783--2794
Perturbation of the Akt/Gsk3-{beta} signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs. [FBrf0213942]
Vazquez-Pianzola et al., 2011, Dev. Biol. 357(2): 404--418
Pabp binds to the osk 3'UTR and specifically contributes to osk mRNA stability and oocyte accumulation. [FBrf0214798]
Venken et al., 2011, Nat. Methods 8(9): 737--743
MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. [FBrf0216331]
von Philipsborn et al., 2011, Neuron 69(3): 509--522
Neuronal control of Drosophila courtship song. [FBrf0212984]
Wang et al., 2011, PLoS Genet. 7(8): e1002227
PP2A-Twins Is Antagonized by Greatwall and Collaborates with Polo for Cell Cycle Progression and Centrosome Attachment to Nuclei in Drosophila Embryos. [FBrf0214683]
Wang et al., 2011, Dev. Cell 21(3): 520--533
An ana2/ctp/mud complex regulates spindle orientation in Drosophila neuroblasts. [FBrf0215580]
Wu et al., 2011, Neuron 70(2): 281--298
A combinatorial semaphorin code instructs the initial steps of sensory circuit assembly in the Drosophila CNS. [FBrf0213571]
Yang et al., 2011, Neuron 72(2): 285--299
Nak regulates localization of clathrin sites in higher-order dendrites to promote local dendrite growth. [FBrf0216477]
Yuan et al., 2011, Science 333(6048): 1458--1462
Light-induced structural and functional plasticity in Drosophila larval visual system. [FBrf0215276]
Zamparini et al., 2011, Development 138(18): 4039--4050
Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila. [FBrf0214783]
Zhang et al., 2011, Mol. Cell 44(4): 572--584
Heterotypic piRNA Ping-Pong Requires Qin, a Protein with Both E3 Ligase and Tudor Domains. [FBrf0216809]
Zheng et al., 2011, Dev. Biol. 357(1): 202--210
magu is required for germline stem cell self-renewal through BMP signaling in the Drosophila testis. [FBrf0214645]
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