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Gene Dmel\RabX1

General Information
Symbol	Dmel\RabX1	Species	D. melanogaster
Name	RabX1	Annotation symbol	CG3870
Feature type	protein_coding_gene	FlyBase ID	FBgn0015372
Gene Model Status	Current	Stock availability	9 publicly available
Also Known As	chrw, DmRabX1
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	59E2-59E2	Sequence location	2R:19,407,362..19,411,096 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene RabX1 is referred to in FlyBase by the symbol Dmel\RabX1 (CG3870, FBgn0015372). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity; GTP binding. There is experimental evidence that it is involved in the biological process: peripheral nervous system development. 10 alleles are reported. The phenotypes of these alleles are annotated with: multidendritic neuron; external sensory organ. It has one annotated transcript and one annotated polypeptide. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rab type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval midgut, larval Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult female reproductive system, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1624618_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of chrw. Gene sequence location is 2R:19407362..19411096.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Controlled Vocabulary Terms synapse
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 59E2-59E2   Limits computationally determined from genome sequence between P{lacW}l(2)s4830s4830&P{lacW}chrwk06908 and P{PZ}Dcp-102132
Experimentally Determined Cytological Location
Cytogenetic map Notes References 59E2-59E2     (Prokopenko, 1999.8.3) 59E2-59E2     (Prokopenko, 1999.11.29) 59E1-59E2   (determined by in situ hybridisation)   (Spradling et al., 1999) 59E1-59E2     (Beaton, 1997.12.27) 59E-59E   (determined by in situ hybridisation)   (Kania et al., 1995) 59E1-59E2     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\RabX1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) RabX1-RA FBtr0072120  NM_079974   1608   261
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein RabX1-PA   FBpp0072029   29.1   261   6.94     NP_524713   AAF47018
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Small GTPase superfamily (IPR001806) Small GTPase superfamily, Rab type (IPR003579) Small GTP-binding protein domain (IPR005225) P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 AAF47018   AF174673   AF174674   AF209706 AAF21440   AI404462   AI515517   AQ025810   AX094008   AY122200 AAM52712   BH854626   BI242681   CO178448   CO268771   CO277785   CO285558   CO289012   CO310425   CO314654   CO336956   CO342207   EC058328   EC085563   EC202083   EC217130   EC219951   EC225868   EC229336   EC242103   EC254800   EC262390   EC268015   GH748138   GH748878   GH749078   GH749214   GH749339   GH749450   GH750015   GH750188   GH750216   GH750465   GH750537   GH750778   GH751277   GH751682   GH752202   GH752684   GH753188   GH753354   GH753465   GH753722   GH753758   GH754325   GH754457   GH754740   GH755356   GH755510   GH755859   GH756070   GH756159   GH756171   GH756921   GH757006   GH757337   GH757461   GH757907   GH758120   GH758238   GH758317   GH758374   GH758687   GH758844   GH758949   GH759350   GH759786   GH760302   GH760583   GH760714   GH760730   GH761088   GH761221   GH770400   GH770548   GH770600   GH770706   GH770869   GH771040   GH771287   GH771499   GH771741   GH771771   GH772273   GH772492   GH772981   GH773040   GH773122   GH773224   GH773366   GH773581   GH773893   GH773918   GH774106   GH774271   GH774352   GH774452   GH774699   GH774717   GH774853   GH775476   GH776133   GH777011   GH777694   GH778140   GH778188   GH778300   GH778516   GH778573   GH778965   GH780089   GH780189   GH781118   GH781355   GH781401   GH782621   GH783982   GH784161   GH784281   GH784632   GH784718   GH784937   GH784964   GH785028   GH785063   GH785293   GH785424   GH785451   GH785466   GH785729   GH786415   GH786478   GH786692   GH786724   GH786740   GH787051   GH787122   GH787123   GH787836   GH787853   GH788300   GH788515   GH789039   GH789761   GH790167   GH790542   GH790699   GH791109   GH791501   GH792208   GH792346   GH792440   GH792518   GH794194   GH794206   GH794930   GH794996   GH795332   GH795746   GH795816   GH796822   GH798021   GH798714   GH799016   GH799475   GH800396   GH800574   GH800659   GH800715   GH801412   GH802219   GH802356   GH802714   GH802909   GH803037   GH803742   GH803765   GH804081   GH804184   GH804777   GH804784   GH805040   GH805166   GH805304   GH805353   GH805372   GH805487   GH805683   GH805792   GH805818   GH805851   GH806074   GH806975   GH806999   GH807212   GH807227   GH807988   GH808209   GH808618   GH808987   GH809760   GH809897   GH810156   GH810865   GH810870   GH810930   GH812752   GH813040   GH813125   GH813627   GH813754   GH813869   GH814260   GH814489   GH815689   GH815805   GH815956   GH815964   GH816168   GH816787   GH816845   GH817093   GH817282   GH817592   GH817604   GH817883   GH818930   GH818947   GH819396   GH819398   GH819761   GH820001   GH820273   GH820545   GH820837   GH821012   GH821067   GH821299   GH821772   GH822213   GH822219   GH822345   GH822352   GH822777   GH822824   GH823435   GH823685   GH823988   GH824209   GH824303   GH824587   GH824671   GH825441   GH825520   GH826112   GH827849   GH827938   GH828449   GH828561   GH828634   GH830059   GH830123   GH830771   GH830778   GH830921   GH830996   GH831193   GH831224   GH831484   GH831655   GH831725   GH831824   GH831885   GH832258   GH832682   GH832753   GH832955   GH833115   GH833394   GH833491   GH834709   GH834752   GH835075   GH835125   GH835288   GH835843   GH835978   GH836090   GH836608   GH836709   GH836914   GH838090   GH839042   GH839775   GH839942   GH840489   GH841172   GH841453   GH841784   GH842372   GH842574   GH842599   GH843010   GH843328   GH843499   GH843935   GH844347   GH845528   GH845619   GH846057   GH846311   GH846458   GH846839   GH846872   GH847020   GH847426   GH847552   GH847625   GH847779   GH848115   GH848283   GH848721   GH848781   GH849961   GH850134   GH850168   GH850322   GH850621   GH851088   GH851982   GH852030   GH852090   GH852405   GH852439   GH852928   GH853000   GH853071   GH853111   GH853257   GH853524   GH853695   GH854704   GH854737   GH854753   GH854763   GH854983   GH855105   GH855291   GH855475   GH855534   GH855554   GH855796   GH856132   GH856534   GH856537   GH857120   GH857735   GH857905   GH858092   GH858729   GH858803   GH859073   GH859098   GH859106   GH859657   GH859921   GH860066   GH860411   GH861515   GH862104   GH862289   GH862515   GH862606   GH862740   GH862930   GH863099   GH863239   GH863374   GH863663   GH863861   GH863870   GH863917   GH864146   GH864983   GH865146   GH865171   GH865205   GH865540   GH865712   GH866067   GH866088   GH866393   GH866479   GH866515   GH867155   GH867419   GH867835   GH868537   GH868683   GH868713   GH868771   GH868983   GH869992   GH870085   GH870421   GH870924   GH871378   GH871491   GH871643   GH872635   GH872696   GH872936   GH873578   GH873785   GH875790   GH875851   GH875864   GH875999   GH876222   GH876674   GH876840   GH877140   GH877212   GH877429   GH877442   GH877621   GH877728   GH877783   GH878359   GH878593   GH878599   GH878971   GH879369   GH879975   GH880287   GH880727   GH881006   GH881198   GH881241   GH882132   GH882367   GH882452   GH882787   GH882953   GH883044   GH883268   GH883386   GH883397   GH883517   GH884919   GH885236   GH885424   GH886593   GH887013   GH887326   GH887474   GH887772   GH888043   GH888238   GH888450   GH888512   GH888814   GH889027   GH889435   GH889496   GH889679   GH890475   GH890660   GH891152   GH891364   GH891611   GH892341   GH893496   GH894566   GH894667   GH895124   GH895491   GH895669   GH896070   GH896443   GH896666   GH896694   GH896705   GH896865   GH897162   GH897417   GH897578   GH897648   GH897822   GH898137   GH898955   GH898962   GH899071   GH899103   GH899267   GH899284   GH899432   GH899829   GH899927   GH900226   GH900299   GH900677   GH900928   GH901000   GH901042   GH901137   GH901375   GH901383   GH902132   GH902343   GH902380   GH902568   GH902782   GH902874   GH903274   GH904448   GH905342   GH905421   GH906276   GH906554   GH906904   GH906910   GH907269   GH907745   GH908277   GH908432   GH908572   GH908874   GH909025   GH910375   GH910686   GH911451   GH911577   GH911593   GH912050   GH912394   GH912566   GH912586   GH912604   GH912737   GH912739   GH912872   GH913099   GH913951   GH914407   GH914606   GH914851   GH915204   GH915763   GH915895   GH917278   GH917510   GH917968   GH918628   GH919001   GH919142   GH919171   GH919332   GH919469   GH919509   GH919672   GH919686   GH919868   GH920049   GH920183   GH920433   GH920758   GH920853   GH921652   GH922557   GH922825   GH922845   GH922993   GH922996   GH923007   GH923193   GH923439   GH923519   GH923564   GH923689   GH924475   GH924567   GH924638   GH924776   GH924814   GH925411   GH925600   GH926322   GH926589   GH926636   GH926647   GH926853   GH927292   GH927320   GH927836   GH927947   GH929517   GH929652   GH929664   GH929773   GH929885   GH930663   GH930910   GH931092   GH931886   GH932123   GH932164   GH932281   GH932287   GH932482   GH932558   GH932830   GH932995   GH933395   GH933551   GH933589   GH933943   GH934506   GH934589   GH934717   GH935068   GH935515   GH936374   GH936546   GH937679   GH938055   GH938170   GH938209   GH938273   GH938298   GH938616   GH939486   GH939773   GH940756
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V3C2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 4 -- 6   organism   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
synapse inferred from direct assay (Chan et al., 2011)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval midgut, larval Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult female reproductive system, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    254 Larval Midgut    259.3 Larval Hindgut    90 Larval Malpighian Tubules    105.6 Larval Fat Body    35.8 Larval Salivary Gland    137.5 Larval Trachea    83.625 Larval Carcass    80.575 Adult Head    87 Adult Eye    130.3 Adult Brain    102.8 Adult Thoracic-Abdominal Ganglion    101.3 Adult Crop    114.9 Adult Midgut    94.1 Adult Hindgut    78.2 Adult Malpighian Tubules    63.6 Adult Fat Body    128.7 Adult Salivary Gland    177.9 Adult Heart    237.85 Adult VirginFemale Spermatheca    103.3 Adult InseminatedFemale Spermatheca    102.7 Adult Ovary    182.6 Adult Testis    129.3 Adult Male Accessory Gland    133.5 Adult Carcass    91.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    87   NA  Eye    130.3   NA  Brain    102.8   254  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    101.3   NA  Crop    114.9   259.3  Midgut    94.1   90  Hindgut    78.2   105.6  Malpighian Tubules    63.6   35.8  Fat Body    128.7   137.5  Salivary Gland    177.9   NA  Heart    237.85   83.625  Trachea    NA   NA  VirginFemale Spermatheca    103.3   NA  InseminatedFemale Spermatheca    102.7   NA  Ovary    182.6   NA  Testis    129.3   NA  Male Accessory Gland    133.5   80.575  Carcass    91.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    49 central nervous system, larvae L3    173 central nervous system, pupae P8    32 head, virgin 1-day female    30 head, virgin 4-day female    36 head, virgin 20-day female    12 head, mated 1-day female    38 head, mated 4-day female    30 head, mated 20-day female    20 head, mated 1-day male    30 head, mated 4-day male    42 head, mated 20-day male    39 salivary gland, larvae L3 wandering    17 salivary gland, white prepupae    28 digestive system, larvae L3 wandering    155 digestive system, 1-day adult    24 digestive system, 4-day adult    37 digestive system, 20-day adult    39 fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8    42 carcass, larvae L3 wandering    38 carcass, 1-day adult    33 carcass, 4-day adult    38 carcass, 20-day adult    26 ovary, virgin 4-day female    56 ovary, mated 4-day female    104 testis, mated 4-day male    36 accessory gland, mated 4-day male    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (49) central nervous system, larvae L3  (173) central nervous system, pupae P8  (32) head, virgin 1-day female  (30) head, virgin 4-day female  (36) head, virgin 20-day female    12 head, mated 1-day female  (38) head, mated 4-day female  (30) head, mated 20-day female    20 head, mated 1-day male  (30) head, mated 4-day male  (42) head, mated 20-day male  (39) salivary gland, larvae L3 wandering    17 salivary gland, white prepupae  (28) digestive system, larvae L3 wandering  (155) digestive system, 1-day adult    24 digestive system, 4-day adult  (37) digestive system, 20-day adult  (39) fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8  (42) carcass, larvae L3 wandering  (38) carcass, 1-day adult  (33) carcass, 4-day adult  (38) carcass, 20-day adult  26 ovary, virgin 4-day female  (56) ovary, mated 4-day female  (104) testis, mated 4-day male  (36) accessory gland, mated 4-day male  (38) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    49 central nervous system, larvae L3  (173) central nervous system, pupae P8    32 head, virgin 1-day female    30 head, virgin 4-day female    36 head, virgin 20-day female    12 head, mated 1-day female    38 head, mated 4-day female    30 head, mated 20-day female    20 head, mated 1-day male    30 head, mated 4-day male    42 head, mated 20-day male    39 salivary gland, larvae L3 wandering    17 salivary gland, white prepupae    28 digestive system, larvae L3 wandering  (155) digestive system, 1-day adult    24 digestive system, 4-day adult    37 digestive system, 20-day adult    39 fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8    42 carcass, larvae L3 wandering    38 carcass, 1-day adult    33 carcass, 4-day adult    38 carcass, 20-day adult    26 ovary, virgin 4-day female    56 ovary, mated 4-day female  104 testis, mated 4-day male    36 accessory gland, mated 4-day male    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    49 central nervous system, larvae L3    173 central nervous system, pupae P8    32 head, virgin 1-day female    30 head, virgin 4-day female    36 head, virgin 20-day female    12 head, mated 1-day female    38 head, mated 4-day female    30 head, mated 20-day female    20 head, mated 1-day male    30 head, mated 4-day male    42 head, mated 20-day male    39 salivary gland, larvae L3 wandering    17 salivary gland, white prepupae    28 digestive system, larvae L3 wandering    155 digestive system, 1-day adult    24 digestive system, 4-day adult    37 digestive system, 20-day adult    39 fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8    42 carcass, larvae L3 wandering    38 carcass, 1-day adult    33 carcass, 4-day adult    38 carcass, 20-day adult    26 ovary, virgin 4-day female    56 ovary, mated 4-day female    104 testis, mated 4-day male    36 accessory gland, mated 4-day male    38 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    49 central nervous system, larvae L3    173 central nervous system, pupae P8    32 head, virgin 1-day female    30 head, virgin 4-day female    36 head, virgin 20-day female    12 head, mated 1-day female    38 head, mated 4-day female    30 head, mated 20-day female    20 head, mated 1-day male    30 head, mated 4-day male    42 head, mated 20-day male    39 salivary gland, larvae L3 wandering    17 salivary gland, white prepupae    28 digestive system, larvae L3 wandering    155 digestive system, 1-day adult    24 digestive system, 4-day adult    37 digestive system, 20-day adult    39 fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8    42 carcass, larvae L3 wandering    38 carcass, 1-day adult    33 carcass, 4-day adult    38 carcass, 20-day adult    26 ovary, virgin 4-day female    56 ovary, mated 4-day female    104 testis, mated 4-day male    36 accessory gland, mated 4-day male    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (49) central nervous system, larvae L3  (173) central nervous system, pupae P8  32 head, virgin 1-day female  30 head, virgin 4-day female  (36) head, virgin 20-day female    12 head, mated 1-day female  (38) head, mated 4-day female  30 head, mated 20-day female    20 head, mated 1-day male  30 head, mated 4-day male  (42) head, mated 20-day male  (39) salivary gland, larvae L3 wandering    17 salivary gland, white prepupae  28 digestive system, larvae L3 wandering  (155) digestive system, 1-day adult    24 digestive system, 4-day adult  (37) digestive system, 20-day adult  (39) fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8  (42) carcass, larvae L3 wandering  (38) carcass, 1-day adult  (33) carcass, 4-day adult  (38) carcass, 20-day adult  26 ovary, virgin 4-day female  (56) ovary, mated 4-day female  (104) testis, mated 4-day male  (36) accessory gland, mated 4-day male  (38) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    49 central nervous system, larvae L3  (173) central nervous system, pupae P8    32 head, virgin 1-day female    30 head, virgin 4-day female    36 head, virgin 20-day female    12 head, mated 1-day female    38 head, mated 4-day female    30 head, mated 20-day female    20 head, mated 1-day male    30 head, mated 4-day male    42 head, mated 20-day male    39 salivary gland, larvae L3 wandering    17 salivary gland, white prepupae    28 digestive system, larvae L3 wandering  (155) digestive system, 1-day adult    24 digestive system, 4-day adult    37 digestive system, 20-day adult    39 fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8    42 carcass, larvae L3 wandering    38 carcass, 1-day adult    33 carcass, 4-day adult    38 carcass, 20-day adult    26 ovary, virgin 4-day female    56 ovary, mated 4-day female  104 testis, mated 4-day male    36 accessory gland, mated 4-day male    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    49 central nervous system, larvae L3    173 central nervous system, pupae P8    32 head, virgin 1-day female    30 head, virgin 4-day female    36 head, virgin 20-day female    12 head, mated 1-day female    38 head, mated 4-day female    30 head, mated 20-day female    20 head, mated 1-day male    30 head, mated 4-day male    42 head, mated 20-day male    39 salivary gland, larvae L3 wandering    17 salivary gland, white prepupae    28 digestive system, larvae L3 wandering    155 digestive system, 1-day adult    24 digestive system, 4-day adult    37 digestive system, 20-day adult    39 fat body, larvae L3 wandering    9 fat body, white prepupae    14 fat body, pupae P8    42 carcass, larvae L3 wandering    38 carcass, 1-day adult    33 carcass, 4-day adult    38 carcass, 20-day adult    26 ovary, virgin 4-day female    56 ovary, mated 4-day female    104 testis, mated 4-day male    36 accessory gland, mated 4-day male    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    40 embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    30 white prepupae new    25 white prepupae 12hr    71 white prepupae 24hr    36 pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day    26 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (45) embryo 02-04hr  (40) embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9  (30) white prepupae new    25 white prepupae 12hr  (71) white prepupae 24hr  (36) pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day  26 adult female 30day  (29) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    40 embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    30 white prepupae new    25 white prepupae 12hr    71 white prepupae 24hr    36 pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day    26 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    40 embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    30 white prepupae new    25 white prepupae 12hr    71 white prepupae 24hr    36 pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day    26 adult female 30day    29 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    40 embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    30 white prepupae new    25 white prepupae 12hr    71 white prepupae 24hr    36 pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day    26 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (45) embryo 02-04hr  (40) embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9  30 white prepupae new    25 white prepupae 12hr  (71) white prepupae 24hr  (36) pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day  26 adult female 30day  29 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    40 embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    30 white prepupae new    25 white prepupae 12hr    71 white prepupae 24hr    36 pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day    26 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    45 embryo 02-04hr    40 embryo 04-06hr    14 embryo 06-08hr    15 embryo 08-10hr    14 embryo 10-12hr    15 embryo 12-14hr    11 embryo 14-16hr    13 embryo 16-18hr    23 embryo 18-20hr    20 embryo 20-22hr    13 embryo 22-24hr    13 larva L1    6 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    13 larva L3 puffstage 3-6    24 larva L3 puffstage 7-9    30 white prepupae new    25 white prepupae 12hr    71 white prepupae 24hr    36 pupae 2d postWPP    25 pupae 3d postWPP    12 pupae 4d postWPP    14 adult male 01day    15 adult male 05day    19 adult male 30day    18 adult female 01day    20 adult female 05day    26 adult female 30day    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    88 Schneider line 2 Sg4    31 embryonic 1182-4H    35 embryonic GM2    41 embryonic Kc167    67 embryonic S1    221 embryonic S3    32 leg disc CME L1    39 wing disc CME-W2    69 wing disc ML-DmD8    62 wing disc ML-DmD9    35 wing disc ML-DmD16-c3    55 wing disc ML-DmD21    44 wing disc ML-DmD32    31 haltere disc ML-DmD17-c3    55 eye-antennal disc ML-DmD11    35 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    169 CNS ML-DmBG1-c1    161 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    42 ovary fGS/OSS    107 ovary OSC    113 ovary OSS    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (88) Schneider line 2 Sg4  (31) embryonic 1182-4H  (35) embryonic GM2  (41) embryonic Kc167  (67) embryonic S1  (221) embryonic S3  (32) leg disc CME L1  (39) wing disc CME-W2  (69) wing disc ML-DmD8  (62) wing disc ML-DmD9  (35) wing disc ML-DmD16-c3  (55) wing disc ML-DmD21  (44) wing disc ML-DmD32  (31) haltere disc ML-DmD17-c3  (55) eye-antennal disc ML-DmD11  (35) antennal disc ML-DmD20-c5  (34) mixed discs ML-DmD4-c1  (169) CNS ML-DmBG1-c1  (161) CNS ML-DmBG2-c2  (80) tumorous blood cells mbn2  (42) ovary fGS/OSS  (107) ovary OSC  (113) ovary OSS  (95) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    88 Schneider line 2 Sg4    31 embryonic 1182-4H    35 embryonic GM2    41 embryonic Kc167    67 embryonic S1  (221) embryonic S3    32 leg disc CME L1    39 wing disc CME-W2    69 wing disc ML-DmD8    62 wing disc ML-DmD9    35 wing disc ML-DmD16-c3    55 wing disc ML-DmD21    44 wing disc ML-DmD32    31 haltere disc ML-DmD17-c3    55 eye-antennal disc ML-DmD11    35 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1  (169) CNS ML-DmBG1-c1  (161) CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    42 ovary fGS/OSS  107 ovary OSC  (113) ovary OSS    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    88 Schneider line 2 Sg4    31 embryonic 1182-4H    35 embryonic GM2    41 embryonic Kc167    67 embryonic S1    221 embryonic S3    32 leg disc CME L1    39 wing disc CME-W2    69 wing disc ML-DmD8    62 wing disc ML-DmD9    35 wing disc ML-DmD16-c3    55 wing disc ML-DmD21    44 wing disc ML-DmD32    31 haltere disc ML-DmD17-c3    55 eye-antennal disc ML-DmD11    35 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    169 CNS ML-DmBG1-c1    161 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    42 ovary fGS/OSS    107 ovary OSC    113 ovary OSS    95 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    88 Schneider line 2 Sg4    31 embryonic 1182-4H    35 embryonic GM2    41 embryonic Kc167    67 embryonic S1    221 embryonic S3    32 leg disc CME L1    39 wing disc CME-W2    69 wing disc ML-DmD8    62 wing disc ML-DmD9    35 wing disc ML-DmD16-c3    55 wing disc ML-DmD21    44 wing disc ML-DmD32    31 haltere disc ML-DmD17-c3    55 eye-antennal disc ML-DmD11    35 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    169 CNS ML-DmBG1-c1    161 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    42 ovary fGS/OSS    107 ovary OSC    113 ovary OSS    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (88) Schneider line 2 Sg4  31 embryonic 1182-4H  (35) embryonic GM2  (41) embryonic Kc167  (67) embryonic S1  (221) embryonic S3  32 leg disc CME L1  (39) wing disc CME-W2  (69) wing disc ML-DmD8  (62) wing disc ML-DmD9  (35) wing disc ML-DmD16-c3  (55) wing disc ML-DmD21  (44) wing disc ML-DmD32  31 haltere disc ML-DmD17-c3  (55) eye-antennal disc ML-DmD11  (35) antennal disc ML-DmD20-c5  (34) mixed discs ML-DmD4-c1  (169) CNS ML-DmBG1-c1  (161) CNS ML-DmBG2-c2  (80) tumorous blood cells mbn2  (42) ovary fGS/OSS  (107) ovary OSC  (113) ovary OSS  (95) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    88 Schneider line 2 Sg4    31 embryonic 1182-4H    35 embryonic GM2    41 embryonic Kc167    67 embryonic S1  (221) embryonic S3    32 leg disc CME L1    39 wing disc CME-W2    69 wing disc ML-DmD8    62 wing disc ML-DmD9    35 wing disc ML-DmD16-c3    55 wing disc ML-DmD21    44 wing disc ML-DmD32    31 haltere disc ML-DmD17-c3    55 eye-antennal disc ML-DmD11    35 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1  (169) CNS ML-DmBG1-c1  (161) CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    42 ovary fGS/OSS  107 ovary OSC  113 ovary OSS    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    88 Schneider line 2 Sg4    31 embryonic 1182-4H    35 embryonic GM2    41 embryonic Kc167    67 embryonic S1    221 embryonic S3    32 leg disc CME L1    39 wing disc CME-W2    69 wing disc ML-DmD8    62 wing disc ML-DmD9    35 wing disc ML-DmD16-c3    55 wing disc ML-DmD21    44 wing disc ML-DmD32    31 haltere disc ML-DmD17-c3    55 eye-antennal disc ML-DmD11    35 antennal disc ML-DmD20-c5    34 mixed discs ML-DmD4-c1    169 CNS ML-DmBG1-c1    161 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    42 ovary fGS/OSS    107 ovary OSC    113 ovary OSS    95 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    57 cold shock, 4-day adult    45 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    97 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    290 Zinc 5 mM 12 hrs, larvae L3    31 Zinc 4.5 mM 48 hrs, 4-day adult    135 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    28 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    94 Caffeine 25 mg/ml 48 hrs, 4-day adult    87 Paraquat 5 mM 48 hrs, 4-day adult    53 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (57) cold shock, 4-day adult  (45) heat shock, 4-day adult  (27) Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3  (33) Cadmium 50 mM 48 hrs, 4-day adult  (45) Cadmium 100 mM 48 hrs, 4-day adult  (97) Copper 0.5 mM 12 hrs, larvae L3  (30) Copper 15 mM 48 hrs, 4-day adult  (290) Zinc 5 mM 12 hrs, larvae L3  (31) Zinc 4.5 mM 48 hrs, 4-day adult  (135) Ethanol 2.5% 3 hrs, larvae L3  (40) Ethanol 5% 3 hrs, larvae L3  (32) Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (28) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (94) Caffeine 25 mg/ml 48 hrs, 4-day adult  (87) Paraquat 5 mM 48 hrs, 4-day adult  (53) Paraquat 10 mM 48 hrs, 4-day adult  (40) Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    57 cold shock, 4-day adult    45 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    97 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult  (290) Zinc 5 mM 12 hrs, larvae L3    31 Zinc 4.5 mM 48 hrs, 4-day adult  (135) Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    28 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    94 Caffeine 25 mg/ml 48 hrs, 4-day adult    87 Paraquat 5 mM 48 hrs, 4-day adult    53 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    57 cold shock, 4-day adult    45 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    97 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    290 Zinc 5 mM 12 hrs, larvae L3    31 Zinc 4.5 mM 48 hrs, 4-day adult    135 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    28 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    94 Caffeine 25 mg/ml 48 hrs, 4-day adult    87 Paraquat 5 mM 48 hrs, 4-day adult    53 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    57 cold shock, 4-day adult    45 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    97 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    290 Zinc 5 mM 12 hrs, larvae L3    31 Zinc 4.5 mM 48 hrs, 4-day adult    135 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    28 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    94 Caffeine 25 mg/ml 48 hrs, 4-day adult    87 Paraquat 5 mM 48 hrs, 4-day adult    53 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (57) cold shock, 4-day adult  (45) heat shock, 4-day adult  27 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3  (33) Cadmium 50 mM 48 hrs, 4-day adult  (45) Cadmium 100 mM 48 hrs, 4-day adult  (97) Copper 0.5 mM 12 hrs, larvae L3  30 Copper 15 mM 48 hrs, 4-day adult  (290) Zinc 5 mM 12 hrs, larvae L3  31 Zinc 4.5 mM 48 hrs, 4-day adult  (135) Ethanol 2.5% 3 hrs, larvae L3  (40) Ethanol 5% 3 hrs, larvae L3  32 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3  28 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (94) Caffeine 25 mg/ml 48 hrs, 4-day adult  (87) Paraquat 5 mM 48 hrs, 4-day adult  (53) Paraquat 10 mM 48 hrs, 4-day adult  (40) Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    57 cold shock, 4-day adult    45 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    97 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult  (290) Zinc 5 mM 12 hrs, larvae L3    31 Zinc 4.5 mM 48 hrs, 4-day adult  135 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    28 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    94 Caffeine 25 mg/ml 48 hrs, 4-day adult    87 Paraquat 5 mM 48 hrs, 4-day adult    53 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    57 cold shock, 4-day adult    45 heat shock, 4-day adult    27 Cadmium 50 mM 6 hrs, larvae L3    16 Cadmium 50 mM 12 hrs, larvae L3    33 Cadmium 50 mM 48 hrs, 4-day adult    45 Cadmium 100 mM 48 hrs, 4-day adult    97 Copper 0.5 mM 12 hrs, larvae L3    30 Copper 15 mM 48 hrs, 4-day adult    290 Zinc 5 mM 12 hrs, larvae L3    31 Zinc 4.5 mM 48 hrs, 4-day adult    135 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    32 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    28 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    94 Caffeine 25 mg/ml 48 hrs, 4-day adult    87 Paraquat 5 mM 48 hrs, 4-day adult    53 Paraquat 10 mM 48 hrs, 4-day adult    40 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_27 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	BDGP expression data • LD47384 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015372 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3870-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive RabX1k06908 Phenotype manifest in Allele chordotonal organ | lateral RabX1k06908 chordotonal organ | ventral RabX1k06908 external sensory organ RabX1k06908 multidendritic neuron RabX1k06908
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of RabX1 Class Mutagen Stocks Known lesion RabX1KG06805 P-element activity 1 -- RabX1ab28 gene conversion P-element activity 0 Yes RabX1bsf36 gene conversion P-element activity 0 Yes RabX1k06908 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of RabX1 Class Mutagen Stocks Known lesion RabX1Q66L.Scer\UAS.P\T.T:Avic\GFP-YFP in vitro construct - amino acid replacement in vitro construct - regulatory fusion in vitro construct - coding region fusion 2 Yes RabX1Scer\UAS.P\T.T:Avic\GFP-YFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 2 Yes RabX1T19N.Scer\UAS.T:Avic\GFP-YFP in vitro construct - amino acid replacement in vitro construct - regulatory fusion in vitro construct - coding region fusion 2 Yes RabX1JF02868 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RabX1KK111671 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes RabX1GD11095 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)BSC661 (Christensen et al., 2008.12.28) Df(2R)bwVDe2LPxKR (Spradling et al., 1999, Kania et al., 1995, Beaton, 1997.12.27) Df(2R)Exel7179 (Ryder, 2004.4.26)
Not disrupted in	Df(2R)bw-S46 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data GAL4 construct PBac{I-SceI(FRT.RabX1-GAL4.ORF(loxP.3xP3-RFP))} No
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}mik06908 No miscellaneous insertions P{hsp26-pt-T}RabX1ab28 NA P{SUPor-P}RabX1KG06805 NA P{UAS-EGFP}RabX1bsf36 NA
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
peripheral nervous system development inferred from mutant phenotype (Prokopenko et al., 2000)
Cellular Component
CV term Evidence References
synapse inferred from direct assay (Chan et al., 2011)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
GTPase activity inferred from sequence or structural similarity (Prokopenko, 1999.11.29) traceable author statement (Prokopenko et al., 2000) GTP binding inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Prokopenko, 1999.11.29)
Biological Process
CV term Evidence References
protein transport inferred from electronic annotation with InterPro:IPR003579 (FlyBase Curators et al., 2004-) small GTPase mediated signal transduction inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
plasma membrane inferred from sequence or structural similarity (Prokopenko, 1999.11.29) vesicle inferred from sequence or structural similarity with Rab11 (Curators, 2008--)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
RabX1 - CG3033 experimental knowledge based (Guruharsha et al., 2011) RabX1 - CG32486 experimental knowledge based (Guruharsha et al., 2011) RabX1 - CG32631 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) RabX1 - CG5044 experimental knowledge based (Guruharsha et al., 2011) RabX1 - CG5568 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) RabX1 - CG5966 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) RabX1 - CG7737 experimental knowledge based (Guruharsha et al., 2011) RabX1 - CG9536 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RabX1 - Clic experimental knowledge based (Guruharsha et al., 2011) RabX1 - Gs1 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) RabX1 - HIP-R experimental knowledge based (Guruharsha et al., 2011) RabX1 - Rab10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) RabX1 - Synd experimental knowledge based (Guruharsha et al., 2011) RabX1 - Yp1 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions RabX1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68877 DroID - A comprehensive database of gene and protein interactions. • FBgn0015372 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44172
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG61VKP5 Dipteran inclusive ortholog search EOG6BCDWW Insect inclusive ortholog search EOG64QRX3 Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search EOG6103SB
Orthologs in Drosophila Species (EOG61VKP5)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\RabX1     Drosophila simulans   Dsim\GD25040 Y   Drosophila sechellia   Dsec\GM15536 Y   Drosophila erecta   Dere\GG20024 Y   Drosophila yakuba   Dyak\GE11561 Y   Drosophila ananassae   Dana\GF11842 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA17740 Y   Drosophila persimilis   Dper\GL17555 Y   Drosophila willistoni   Dwil\GK23050 Y   Drosophila virilis   Dvir\GJ19978 Y   Drosophila mojavensis   Dmoj\GI19016 Y   Drosophila grimshawi   Dgri\GH20651 Y
Orthologs in non-Drosophila Dipterans (EOG6BCDWW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011171   Anopheles gambiae Malaria mosquito  Agam\AGAP006159   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004760
Orthologs in non-Dipteran Insects (EOG64QRX3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB54749   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012363   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17632   Atta cephalotes Leafcutter ant  Acep\ACEP15379   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20037   Linepithema humile Argentine ant  Lhum\LH16529   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14737   Solenopsis invicta Red fire ant  Sinv\SINV10219   Acyrthosiphon pisum Pea aphid  Apim\ACYPI003022   Bombyx mori Silkmoth  Bmor\BGIBMGA003266   Tribolium castaneum Red flour beetle  Tcas\TC009462
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (EOG6103SB)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rab-21 Y Caenorhabditis elegans Nematode  Cele\C56E6.2 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_022991gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_000927gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_011961gn Y Danio rerio Zebrafish  Drer\zgc:154045 Y Xenopus tropicalis Western clawed frog  Xtro\rab21 Y Gallus gallus Domestic chicken  Ggal\RAB21 Y Mus musculus House mouse  Mmus\Rab21 Y Rattus norvegicus Norway rat  Rnor\Rab21 Y Homo sapiens Human  Hsap\RAB21 Y
Human Orthologs (1)
Gene OMIM HGNC Hsap\RAB21
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD25040 Drosophila sechellia Dsec\GM15536 Drosophila erecta Dere\GG20024 Drosophila yakuba Dyak\GE11561 Drosophila ananassae Dana\GF11842 Drosophila pseudoobscura pseudoobscura Dpse\GA17740 Drosophila persimilis Dper\GL17555 Drosophila willistoni Dwil\GK23050 Drosophila virilis Dvir\GJ19978 Drosophila mojavensis Dmoj\GI19016 Drosophila grimshawi Dgri\GH20651
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	9840 y1 w*; P{UASp-YFP.RabX1}12 23274 y1 w*; P{UASp-YFP.RabX1}10 28033 y1 v1; P{TRiP.JF02868}attP2 9837 y1 w*; P{UASp-YFP.RabX1.Q66L}02 9839 y1 w*; P{UASp-YFP.RabX1.Q66L}10 14502 y1 w67c23; P{SUPor-P}RabX1KG06805 9838 y1 w*; P{UAST-YFP.RabX1.T19N}Pabp201/SM5 23252 y1 w*; P{UAST-YFP.RabX1.T19N}Oseg414/TM3, Sb1
VDRC	v103039 P{KK111671}VIE-260B
Genomic Clones ( 2 )
	BACR25I01 BACR48M01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 634 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD47384
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH24196 RE40078
Other clones	56719 99133 118054 214307.30 562014 571389 CK01.26B.H8 CK01.71C.A2 CK01.88D.C11 CK01.116D.D2 CK01.121A.B4 EK056725 EK069911 EK092638 EK126405 EK169247 EK221621 EK237352 EN13541 EP14147 RP003001579 RP003001837 RP003002465 RP003002502 RP003003644 RP003004792 RP003004923 RP003005640 RP003006272 RP003006933 RP003008876 RP003009782 RP003010268 RP003012607 RP003013649 RP003014796 RP003015723 RP003015767 RP003017197 RP003017408 RP003017644 RP003018391 RP003019458 RP003019688 RP003019885 RP003020443 RP003020444 RP003021763 RP003023121 RP003023381 RP003024728 RP003025079 RP003028100 RP003029239 RP003029444 RP003030494 RP003031541 RP003031964 RP003032342 RP003032744 RP003033007 RP003033537 RP003034364 RP003034677 RP003036111 RP003036907 RP003037947 RP003038620 RP003040471 RP003040739 RP003041299 RP003041388 RP003041402 RP003042155 RP003042367 RP003043366 RP003043493 RP003045247 RP003045737 RP003048878 RP003050676 RP003054769 RP003054793 RP003054960 RP003055592 RP003058712 RP003059193 RP003059352 RP003060092 RP003061192 RP003063206 RP003063240 RP003063435 RP003064047 RP003065030 RP003065269 RP003065310 RP003065479 RP003066317 RP003069914 RP003069958 RP003070960 RP003071415 RP003072382 RP003073530 RP003075011 RP003075368 RP003076022 RP003077775 RP003078157 RP003078185 RP003078378 RP003078979 RP003079615 RP003080250 RP003085938 RP003086070 RP003090746 RP003091286 RP003091576 RP003091925 RP003093839 RP003093914 RP003094450 RP003096571 RP003096657 RP003096698 RP003098052 RP003098717 RP003098840 RP003099270 RP003100424 RP003101007 RP003101197 RP003104600 RP003105755 RP003108970 RP003110880 RP003111367 RP003113523 RP003113671 RP003114472 RP003115291 RP003117173 RP003120812 RP003121882 RP003122132 RP003122202 RP003122911 RP003123053 RP003123947 RP003124413 RP003125549 RP003126020 RP003127386 RP003127620 RP003127724 RP003129113 RP003130686 RP003131090 RP003133418 RP003133918 RP003137473 RP003137621 RP003137647 RP003137829 RP003139765 RP003139969 RP003141453 RP003142630 RP003144473 RP003144965 RP003145693 RP003146200 RP003146527 RP003149598 RP003149920 RP003152675 RP003153629 RP003154180 RP003154809 RP003160698 RP003161026 RP003161810 RP003162223 RP003164607 RP003164608 RP003166126 RP003166369 RP003166962 RP003167330 RP003167388 RP003167891 RP003170166 RP003170663 RP003172558 RP003172776 RP003174691 RP003175324 RP003176582 RP003177107 RP003177975 RP003178314 RP003180069 RP003182594 RP003182624 RP003182686 RP003183490 RP003183764 RP003184562 RP003184594 RP003185765 RP003185910 RP003187999 RP003188207 RP003190141 RP003192840 RP003193868 RP003194449 RP003195391 RP003196283 RP003196536 RP003196717 RP003197478 RP003197654 RP003197928 RP003198828 RP003198923 RP003199195 RP003201169 RP003201185 RP003202589 RP003206795 RP003207349 RP003209118 RP003210452 RP003211000 RP003211492 RP003211841 RP003212648 RP003213796 RP003215252 RP003216650 RP003217725 RP003218022 RP003218262 RP003218698 RP003219973 RP003220027 RP003222096 RP003223194 RP003223995 RP003224846 RP003225041 RP003225601 RP003226428 RP003227126 RP003230887 RP003231049 RP003231063 RP003231495 RP003232353 RP003233143 RP003234240 RP003234371 RP003234566 RP003235819 RP003237732 RP003238439 RP003238515 RP003238988 RP003239948 RP003240487 RP003240685 RP003240863 RP003245922 RP003247028 RP003248520 RP003249662 RP003251256 RP003251398 RP003252059 RP003252490 RP003252493 RP003253042 RP003255399 RP003257249 RP003258862 RP003258929 RP003259201 RP003260234 RP003260282 RP003260359 RP003263037 RP003263165 RP003264727 RP003265965 RP003266890 RP003268475 RP003268874 RP003269509 RP003271071 RP003274826 RP003276098 RP003276407 RP003278819 RP003279868 RP003280125 RP003280643 RP003280757 RP003282243 RP003282434 RP003282438 RP003282570 RP003282929 RP003284966 RP003285241 RP003285988 RP003287315 RP003287854 RP003288044 RP003288920 RP003289398 RP003289728 RP003289899 RP003291537 RP003293575 RP003294081 RP003294940 RP003295031 RP003295450 RP003297467 RP003298428 RP003298927 RP003298982 RP003299067 RP003299296 RP003299717 RP003299838 RP003301468 RP003304181 RP003304609 RP003305173 RP003305933 RP003307367 RP003311665 RP003312904 RP003313671 RP003318318 RP003319820 RP003326590 RP003328302 RP003329062 RP003330118 RP003330140 RP003330252 RP003331759 RP003333224 RP003334178 RP003335316 RP003337724 RP003337997 RP003338137 RP003338454 RP003339702 RP003341890 RP003342123 RP003342343 RP003343689 RP003345938 RP003346884 RP003347333 RP003348525 RP003352041 RP003352681 RP003353532 RP003354637 RP003356067 RP003356618 RP003356861 RP003356867 RP003357421 RP003359428 RP003359698 RP003361546 RP003362355 RP003364076 RP003364831 RP003365074 RP003365817 RP003368355 RP003370688 RP003370881 RP003371103 RP003371533 RP003371801 RP003371975 RP003372288 RP003373556 RP003374095 RP003378379 RP003378938 RP003378999 RP003379539 RP003380520 RP003381350 RP003383076 RP003383179 RP003384780 RP003386324 RP003387522 RP003387575 RP003387725 RP003389930 RP003390034 RP003390113 RP003392641 RP003392749 RP003394603 RP003394923 RP003397894 RP003398038 RP003398058 RP003398922 RP003399945 RP003400911 RP003404380 RP003406371 RP003406976 RP003407514 RP003408702 RP003410357 RP003413102 RP003413421 RP003414010 RP003415468 RP003416584 RP003416961 RP003417105 RP003417281 RP003418087 RP003418845 RP003420236 RP003421650 RP003421890 RP003422132 RP003422804 RP003425445 RP003426229 RP003428658 RP003430673 RP003430880 RP003431581 RP003434159 RP003436132 RP003436139 RP003439210 RP003440024 RP003442693 RP003443036 RP003444308 RP003444409 RP003445226 RP003445389 RP003446688 RP003446902 RP003447142 RP003447886 RP003451706 RP003452968 RP003453394 RP003453644 RP003456560 RP003457252 RP003457522 RP003457827 RP003458253 RP003460039 RP003460259 RP003460509 RP003461786 RP003462323 RP003462800 RP003466848 RP003468148 RP003471684 RP003473591 RP003476567 RP003477291 RP003479709 RP003482547 RP003482657 RP003483978 RP003484060 RP003486906 RP003488101 RP003489027 RP003489403 RP003489534 RP003489660 RP003490537 RP003490781 RP003490859 RP003492575 RP003494767 RP003497676 RP003499607 RP003502178 RP003504112 RP003505585 RP003509029 RP003510380 RP003512169 RP003514630 RP003516979 RP003517502 RP003519092 RP003520341 RP003520507 RP003520601 RP003520820 RP003525122 RP003526882 RP003527770 RP003528995 RP003529716 RP003529814 RP003529875 RP003530916 RP003533271 RP003538774 RP003541637 RP003542530 RP003543052 RP003544803 RP003545062 RP003545487 RP003545842 RP003546161 RP003546344 RP003548278 RP003548856 RP003549013 RP003551155 RP003551481 RP003553349 RP003557682 RP003559880 RP003561360 RP003562735 RP003563254 RP003563672 RP003565459 RP003566397 RP003567548 RP003567730 RP003569475 RP003569654 RP003570551 RP003571070 RP003571241 RP003573557 RP003574011 RP003574270 RP003574428 RP003575381 RP003577761 RP003578087 RP003578659 RP003583668 RP003590218 RP003592477 RP003598175 RP003600882 RP003601332 RP003602098 RP003608627 RP003609551 RP003611408 RP003611466 RP003615419 RP003615425 RP003616373 RP003618223 RP003619310 RP003619423 RP003622244 RP003623536 RP003625196 RP003630636 RP003630749 RP003632264 RP003632539 RP003632872 RP003633118 RP003633438 RP003634283 RP003637366 RP003637597 RP003637657 RP003638137 RP003639791 RP003646208 RP003647050 RP003647522 RP003648673 RP003650073 RP003650218 RP003652677 RP003652915 RP003653245 RP003653476 RP003655749 RP003659113 RP003662066 RP003662262 RP003663302 RP003664987 RP003665881 RP003671794 RP003671857 RP003672687 RP003675521 RP003675865 RP003676115 RP003677131 RP003680616 RP003680909 RP003681011 RP003682123 RP003682527
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0015372 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44172
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: RabX1 chrw (Bellen, 2012.7.24)
Source for database merge of	Source for merge of: chrw CG3870 (Bayraktaroglu, 2000.8.7)
Additional comments
Other Comments
	dsRNA has been made from templates generated with primers directed against this gene. (Kouranti et al., 2006) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Area matching Drosophila ESTs AI515517 and AI404462. ESTs have sequence similarity to Ras related proteins. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079974 RefSeq (Proteins) • NP_524713 DDBJ / EMBL / GenBank • AAF21440 AAF47018 AAM52712 AF174673 AF174674 AF209706 AI404462 AI515517 AQ025810 AX094008 AY122200 BH854626 Entrez Gene - A searchable database of RefSeq genes. • 44172 UniProtKB/TrEMBL • Q9V3C2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Small GTPase superfamily (IPR001806) Small GTPase superfamily, Rab type (IPR003579) Small GTP-binding protein domain (IPR005225) P-loop containing nucleoside triphosphate hydrolase (IPR027417) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD47384
Linkouts
	BioGRID - A database of protein and genetic interactions • 68877 DroID - A comprehensive database of gene and protein interactions. • FBgn0015372 DRSC - Results from RNAi screens. • FBgn0015372 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015372 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3870-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0015372 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44172 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44172 modMine - Data generated by the modENCODE project. • FBgn0015372
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	AAF47018 (Armstrong, 2000) CG3870 (Zhang et al., 2007, Dorer et al., 2006, Keleman et al., 2009.8.5, Perkins et al., 2009, Colicelli, 2004) chr (Kania et al., 1995) chrw (Font-Burgada et al., 2008, Nisha et al., 2008, Sage et al., 2008, Bakal et al., 2007, Christensen et al., 2008.12.28) Chrw (Kim et al., 2005) DmRabX1 (Pereira-Leal and Seabra, 2001, Pereira-Leal and Seabra, 2001) l(2)k06908 (Beaton, 1997.12.27) RAB5c (Dorer et al., 2006) RabX1 (Kouranti et al., 2006, Zhang et al., 2007, Zhang et al., 2007, Bellen, 2012.7.24) rabX1 (Chan et al., 2011, Jin et al., 2012)
Name Synonym	chrowded (Kania et al., 1995, Johansson et al., 2005) RabX1
Secondary FlyBase IDs
	FBgn0034872
References ( 48 )
Generate a list of	All references relating to this gene ( 48 )
List References by type	Research paper  ( 16 ) Supplementary material  ( 8 ) Review  ( 2 ) Personal communication to FlyBase  ( 12 ) Abstract  ( 1 ) FlyBase analysis  ( 3 ) Patent  ( 1 ) DNA/RNA sequence record  ( 3 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 3 )
	Jin et al., 2012, PLoS ONE 7(7): e40912 Similarities of Drosophila rab GTPases Based on Expression Profiling: Completion and Analysis of the rab-Gal4 Kit. [FBrf0219021] Chan et al., 2011, Curr. Biol. 21(20): 1704--1715 Systematic discovery of rab GTPases with synaptic functions in Drosophila. [FBrf0216517] Uytterhoeven et al., 2011, Cell 145(1): 117--132 Loss of skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteins. [FBrf0213384] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...