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Gene Dmel\dod

General Information
Symbol	Dmel\dod	Species	D. melanogaster
Name	dodo	Annotation symbol	CG17051
Feature type	protein_coding_gene	FlyBase ID	FBgn0015379
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	Pin1
Genomic Location
Chromosome (arm)	X	Recombination map	1-
Cytogenetic map	19F5-19F5	Sequence location	X:21,216,385..21,217,885 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene dodo is referred to in FlyBase by the symbol Dmel\dod (CG17051, FBgn0015379). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: peptidyl-prolyl cis-trans isomerase activity. There is experimental evidence that it is involved in the biological process: epidermal growth factor receptor signaling pathway. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidyl-prolyl cis-trans isomerase, PpiC-type; Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site; WW domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1636396_at partially aligns to an exonic region of the only FlyBase-annotated transcript isoform of dod: 8 out of 14 probes fall into this exonic region. Gene sequence location is X:21216385..21217885.
User Contributed Data
	Beta version, feedback welcome
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 19F5-19F5   Limits computationally determined from genome sequence between P{EP}CG1702EP1525 and P{EP}EP1465&P{EP}CG1486EP1192
Experimentally Determined Cytological Location
Cytogenetic map Notes References 19F-19F     (Maleszka, 1995.8.31) 19F-19F   Deduced from proximity to fliI. (determined by in situ hybridisation)   (Campbell et al., 1993)
Experimentally Determined Recombination Data
Location	1- (Maleszka, 1995.8.31)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\dod for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48 Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) dod-RA FBtr0077193  NM_078704   1021   166
Additional Transcript Data & Comments
Reported size (kB)	1.0 (longest cDNA) (Maleszka et al., 1996)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein dod-PA   FBpp0076894   18.4   166   7.57     NP_523428   AAF50829
Additional Polypeptide Data & Comments
Reported size (kDa)	166 (aa) (Maleszka et al., 1996, Maleszka et al., 1998)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidyl-prolyl cis-trans isomerase, PpiC-type (IPR000297) WW domain (IPR001202) Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site (IPR023058)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA694723   AE014298 AAF50829   AF017777 AAC28408   AI064155   AI406265   AI515687   AI515690   BE978350   BI353989   BI637033   BP548795   BP548796   BT099557   CK605529   CK605530   CO191022   CO277497   CO277613   CO312093   CO315450   CO321663   CO330406   EC051400   EC051401   EC051431   EC052420   EC054380   EC054941   EC060298   EC066380   EC076439   EC232285   EC234909   EL879118   EL879119   EV582780   U35140 AAC46958   Z32455   Z83517
UniProtKB/Swiss-Prot	P54353
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
nucleus inferred from direct assay (Hsu et al., 2001)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    72.525 Larval Midgut    15.4 Larval Hindgut    20 Larval Malpighian Tubules    15.4 Larval Fat Body    9.6 Larval Salivary Gland    32.2 Larval Trachea    43.775 Larval Carcass    26.425 Adult Head    33.8 Adult Eye    40.325 Adult Brain    71 Adult Thoracic-Abdominal Ganglion    82.2 Adult Crop    25 Adult Midgut    17.6 Adult Hindgut    25 Adult Malpighian Tubules    21.1 Adult Fat Body    21.1 Adult Salivary Gland    24.1 Adult Heart    21.95 Adult VirginFemale Spermatheca    19.2 Adult InseminatedFemale Spermatheca    18.8 Adult Ovary    43.3 Adult Testis    4.9 Adult Male Accessory Gland    10.8 Adult Carcass    30.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    33.8   NA  Eye    40.325   NA  Brain    71   72.525  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    82.2   NA  Crop    25   no informative data  Midgut    17.6   20  Hindgut    25   no informative data  Malpighian Tubules    no informative data   9.6  Fat Body    21.1   no informative data  Salivary Gland    no informative data   NA  Heart    21.95   43.775  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    18.8   NA  Ovary    43.3   NA  Testis    4.9   NA  Male Accessory Gland    no informative data   26.425  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    42 central nervous system, larvae L3    36 central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female    28 ovary, mated 4-day female    29 testis, mated 4-day male    43 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (42) central nervous system, larvae L3  (36) central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female  (28) ovary, mated 4-day female  (29) testis, mated 4-day male  (43) accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    42 central nervous system, larvae L3    36 central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female    28 ovary, mated 4-day female    29 testis, mated 4-day male    43 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    42 central nervous system, larvae L3    36 central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female    28 ovary, mated 4-day female    29 testis, mated 4-day male    43 accessory gland, mated 4-day male    16 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    42 central nervous system, larvae L3    36 central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female    28 ovary, mated 4-day female    29 testis, mated 4-day male    43 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (42) central nervous system, larvae L3  (36) central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female  28 ovary, mated 4-day female  29 testis, mated 4-day male  (43) accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    42 central nervous system, larvae L3    36 central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female    28 ovary, mated 4-day female    29 testis, mated 4-day male    43 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    42 central nervous system, larvae L3    36 central nervous system, pupae P8    24 head, virgin 1-day female    7 head, virgin 4-day female    9 head, virgin 20-day female    5 head, mated 1-day female    7 head, mated 4-day female    8 head, mated 20-day female    7 head, mated 1-day male    8 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    7 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    9 digestive system, 4-day adult    12 digestive system, 20-day adult    11 fat body, larvae L3 wandering    7 fat body, white prepupae    9 fat body, pupae P8    14 carcass, larvae L3 wandering    23 carcass, 1-day adult    5 carcass, 4-day adult    7 carcass, 20-day adult    8 ovary, virgin 4-day female    28 ovary, mated 4-day female    29 testis, mated 4-day male    43 accessory gland, mated 4-day male    16 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    91 embryo 02-04hr    104 embryo 04-06hr    92 embryo 06-08hr    81 embryo 08-10hr    57 embryo 10-12hr    50 embryo 12-14hr    30 embryo 14-16hr    29 embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1    30 larva L2    37 larva L3 12hr old    30 larva L3 puffstage 1-2    29 larva L3 puffstage 3-6    39 larva L3 puffstage 7-9    37 white prepupae new    38 white prepupae 12hr    39 white prepupae 24hr    60 pupae 2d postWPP    41 pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day    26 adult male 05day    34 adult male 30day    34 adult female 01day    41 adult female 05day    53 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (91) embryo 02-04hr  (104) embryo 04-06hr  (92) embryo 06-08hr  (81) embryo 08-10hr  (57) embryo 10-12hr  (50) embryo 12-14hr  (30) embryo 14-16hr  (29) embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1  (30) larva L2  (37) larva L3 12hr old  (30) larva L3 puffstage 1-2  (29) larva L3 puffstage 3-6  (39) larva L3 puffstage 7-9  (37) white prepupae new  (38) white prepupae 12hr  (39) white prepupae 24hr  (60) pupae 2d postWPP  (41) pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day  26 adult male 05day  (34) adult male 30day  (34) adult female 01day  (41) adult female 05day  (53) adult female 30day  (58) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    91 embryo 02-04hr  104 embryo 04-06hr    92 embryo 06-08hr    81 embryo 08-10hr    57 embryo 10-12hr    50 embryo 12-14hr    30 embryo 14-16hr    29 embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1    30 larva L2    37 larva L3 12hr old    30 larva L3 puffstage 1-2    29 larva L3 puffstage 3-6    39 larva L3 puffstage 7-9    37 white prepupae new    38 white prepupae 12hr    39 white prepupae 24hr    60 pupae 2d postWPP    41 pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day    26 adult male 05day    34 adult male 30day    34 adult female 01day    41 adult female 05day    53 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    91 embryo 02-04hr    104 embryo 04-06hr    92 embryo 06-08hr    81 embryo 08-10hr    57 embryo 10-12hr    50 embryo 12-14hr    30 embryo 14-16hr    29 embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1    30 larva L2    37 larva L3 12hr old    30 larva L3 puffstage 1-2    29 larva L3 puffstage 3-6    39 larva L3 puffstage 7-9    37 white prepupae new    38 white prepupae 12hr    39 white prepupae 24hr    60 pupae 2d postWPP    41 pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day    26 adult male 05day    34 adult male 30day    34 adult female 01day    41 adult female 05day    53 adult female 30day    58 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    91 embryo 02-04hr    104 embryo 04-06hr    92 embryo 06-08hr    81 embryo 08-10hr    57 embryo 10-12hr    50 embryo 12-14hr    30 embryo 14-16hr    29 embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1    30 larva L2    37 larva L3 12hr old    30 larva L3 puffstage 1-2    29 larva L3 puffstage 3-6    39 larva L3 puffstage 7-9    37 white prepupae new    38 white prepupae 12hr    39 white prepupae 24hr    60 pupae 2d postWPP    41 pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day    26 adult male 05day    34 adult male 30day    34 adult female 01day    41 adult female 05day    53 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (91) embryo 02-04hr  (104) embryo 04-06hr  (92) embryo 06-08hr  (81) embryo 08-10hr  (57) embryo 10-12hr  (50) embryo 12-14hr  30 embryo 14-16hr  29 embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1  30 larva L2  (37) larva L3 12hr old  30 larva L3 puffstage 1-2  29 larva L3 puffstage 3-6  (39) larva L3 puffstage 7-9  (37) white prepupae new  (38) white prepupae 12hr  (39) white prepupae 24hr  (60) pupae 2d postWPP  (41) pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day  26 adult male 05day  (34) adult male 30day  (34) adult female 01day  (41) adult female 05day  (53) adult female 30day  (58) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    91 embryo 02-04hr  104 embryo 04-06hr    92 embryo 06-08hr    81 embryo 08-10hr    57 embryo 10-12hr    50 embryo 12-14hr    30 embryo 14-16hr    29 embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1    30 larva L2    37 larva L3 12hr old    30 larva L3 puffstage 1-2    29 larva L3 puffstage 3-6    39 larva L3 puffstage 7-9    37 white prepupae new    38 white prepupae 12hr    39 white prepupae 24hr    60 pupae 2d postWPP    41 pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day    26 adult male 05day    34 adult male 30day    34 adult female 01day    41 adult female 05day    53 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    91 embryo 02-04hr    104 embryo 04-06hr    92 embryo 06-08hr    81 embryo 08-10hr    57 embryo 10-12hr    50 embryo 12-14hr    30 embryo 14-16hr    29 embryo 16-18hr    19 embryo 18-20hr    15 embryo 20-22hr    13 embryo 22-24hr    10 larva L1    30 larva L2    37 larva L3 12hr old    30 larva L3 puffstage 1-2    29 larva L3 puffstage 3-6    39 larva L3 puffstage 7-9    37 white prepupae new    38 white prepupae 12hr    39 white prepupae 24hr    60 pupae 2d postWPP    41 pupae 3d postWPP    25 pupae 4d postWPP    21 adult male 01day    26 adult male 05day    34 adult male 30day    34 adult female 01day    41 adult female 05day    53 adult female 30day    58 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    70 Schneider line 2 Sg4    43 embryonic 1182-4H    34 embryonic GM2    13 embryonic Kc167    24 embryonic S1    40 embryonic S3    23 leg disc CME L1    48 wing disc CME-W2    26 wing disc ML-DmD8    28 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    64 wing disc ML-DmD32    37 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    33 ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (70) Schneider line 2 Sg4  (43) embryonic 1182-4H  (34) embryonic GM2    13 embryonic Kc167    24 embryonic S1  (40) embryonic S3    23 leg disc CME L1  (48) wing disc CME-W2  26 wing disc ML-DmD8  (28) wing disc ML-DmD9  (46) wing disc ML-DmD16-c3  (40) wing disc ML-DmD21  (64) wing disc ML-DmD32  (37) haltere disc ML-DmD17-c3  (33) eye-antennal disc ML-DmD11  (43) antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1  (39) CNS ML-DmBG1-c1  (45) CNS ML-DmBG2-c2  (28) tumorous blood cells mbn2  (33) ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    70 Schneider line 2 Sg4    43 embryonic 1182-4H    34 embryonic GM2    13 embryonic Kc167    24 embryonic S1    40 embryonic S3    23 leg disc CME L1    48 wing disc CME-W2    26 wing disc ML-DmD8    28 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    64 wing disc ML-DmD32    37 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    33 ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    70 Schneider line 2 Sg4    43 embryonic 1182-4H    34 embryonic GM2    13 embryonic Kc167    24 embryonic S1    40 embryonic S3    23 leg disc CME L1    48 wing disc CME-W2    26 wing disc ML-DmD8    28 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    64 wing disc ML-DmD32    37 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    33 ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    70 Schneider line 2 Sg4    43 embryonic 1182-4H    34 embryonic GM2    13 embryonic Kc167    24 embryonic S1    40 embryonic S3    23 leg disc CME L1    48 wing disc CME-W2    26 wing disc ML-DmD8    28 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    64 wing disc ML-DmD32    37 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    33 ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (70) Schneider line 2 Sg4  (43) embryonic 1182-4H  (34) embryonic GM2    13 embryonic Kc167    24 embryonic S1  (40) embryonic S3    23 leg disc CME L1  (48) wing disc CME-W2  26 wing disc ML-DmD8  28 wing disc ML-DmD9  (46) wing disc ML-DmD16-c3  (40) wing disc ML-DmD21  (64) wing disc ML-DmD32  (37) haltere disc ML-DmD17-c3  (33) eye-antennal disc ML-DmD11  (43) antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1  (39) CNS ML-DmBG1-c1  (45) CNS ML-DmBG2-c2  28 tumorous blood cells mbn2  (33) ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    70 Schneider line 2 Sg4    43 embryonic 1182-4H    34 embryonic GM2    13 embryonic Kc167    24 embryonic S1    40 embryonic S3    23 leg disc CME L1    48 wing disc CME-W2    26 wing disc ML-DmD8    28 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    64 wing disc ML-DmD32    37 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    33 ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    70 Schneider line 2 Sg4    43 embryonic 1182-4H    34 embryonic GM2    13 embryonic Kc167    24 embryonic S1    40 embryonic S3    23 leg disc CME L1    48 wing disc CME-W2    26 wing disc ML-DmD8    28 wing disc ML-DmD9    46 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    64 wing disc ML-DmD32    37 haltere disc ML-DmD17-c3    33 eye-antennal disc ML-DmD11    43 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    39 CNS ML-DmBG1-c1    45 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    33 ovary fGS/OSS    18 ovary OSC    24 ovary OSS    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult    26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult  26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  (27) Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3  (34) Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult  (27) Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult    26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult    26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult    26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult  26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult  27 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3  (34) Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult  27 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult    26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    12 cold shock, 4-day adult    13 heat shock, 4-day adult    26 Cadmium 50 mM 6 hrs, larvae L3    25 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    17 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    16 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    14 Zinc 4.5 mM 48 hrs, 4-day adult    13 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    12 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    25 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    20 Paraquat 10 mM 48 hrs, 4-day adult    27 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015379 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17051-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 dodGD9274 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of dod Class Mutagen Stocks Known lesion dodEY03779 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of dod Class Mutagen Stocks Known lesion dodGD9274 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes dodAct5C.PH in vitro construct - regulatory fusion 0 Yes dodhs.PH in vitro construct - regulatory fusion 0 Yes dodKK108535 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dodNIG.17051R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes dodT2 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)16-129 (Maleszka et al., 1996) Df(1)17-257 (Maleszka et al., 1996) Df(1)GA104 (Maleszka et al., 1996)
Not disrupted in	Df(1)2/19B (Maleszka et al., 1996)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9274} NA P{KK108535} NA P{NIG.17051R} NA heat-shock construct P{hs-dod.H} NA characterization construct P{penT2} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}dodEY03779 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
epidermal growth factor receptor signaling pathway inferred from mutant phenotype (Hsu et al., 2001)
Cellular Component
CV term Evidence References
nucleus inferred from direct assay (Hsu et al., 2001)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
peptidyl-prolyl cis-trans isomerase activity inferred from sequence or structural similarity (Hanes et al., 1996) inferred from sequence or structural similarity with human PIN1 AND inferred from sequence or structural similarity with Saccharomyces ESS1 (Maleszka et al., 1996) inferred from sequence or structural similarity with NCBI_gi:5453898 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1996.10.1)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
dod - Akap200 experimental knowledge based (Guruharsha et al., 2011) dod - AnxB10 experimental knowledge based (Guruharsha et al., 2011) dod - Bacc experimental knowledge based (Guruharsha et al., 2011) dod - CG1024 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG10265 experimental knowledge based (Guruharsha et al., 2011) dod - CG10638 experimental knowledge based (Guruharsha et al., 2011) dod - CG1307 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG1340 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG13870 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG16898 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG1910 experimental knowledge based (Guruharsha et al., 2011) dod - CG2852 experimental knowledge based (Guruharsha et al., 2011) dod - CG30339 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) dod - CG3036 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG31917 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) dod - CG31961 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG3618 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG4300 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG4619 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG4866 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG4998 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG6283 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) dod - CG7656 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) dod - CG7668 experimental knowledge based (Guruharsha et al., 2011) dod - CG7739 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG8891 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - CG9062 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Chd64 experimental knowledge based (Guruharsha et al., 2011) dod - Crc experimental knowledge based (Guruharsha et al., 2011) dod - Cyp28a5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - D1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Df31 experimental knowledge based (Guruharsha et al., 2011) dod - FK506-bp2 experimental knowledge based (Guruharsha et al., 2011) dod - Golgin84 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - GstO3 experimental knowledge based (Guruharsha et al., 2011) dod - Hcs anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Hsp60B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Inos experimental knowledge based (Guruharsha et al., 2011) dod - Nlp experimental knowledge based (Guruharsha et al., 2011) dod - Oat anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Obp56h anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) dod - PHGPx experimental knowledge based (Guruharsha et al., 2011) dod - Proct anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Prx2540-2 experimental knowledge based (Guruharsha et al., 2011) dod - Pten anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Rcd-1r anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Ser12 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Sh3β experimental knowledge based (Guruharsha et al., 2011) dod - Snx3 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) dod - Su(var)3-3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - TpnC25D experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) dod - UbcD4 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) dod - Ugt58Fa anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - Vha100-4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - awd experimental knowledge based (Guruharsha et al., 2011) dod - bai anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - eIF-1A anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) dod - eIF4E-4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - fabp experimental knowledge based (Guruharsha et al., 2011) dod - htl anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - ldbr anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - msl-3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - nemy anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) dod - smt3 experimental knowledge based (Guruharsha et al., 2011) dod - sunz anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions dod allele Gene References dodhs.PH phl (Hsu et al., 2001)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59389 DroID - A comprehensive database of gene and protein interactions. • FBgn0015379 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33111 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • P54353
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6K9BZS Dipteran inclusive ortholog search EOG6VDQ7V Insect inclusive ortholog search EOG6WWQG2 Arthropod inclusive ortholog search EOG6ZKH3S Metazoa inclusive ortholog search EOG67MDSX
Orthologs in Drosophila Species (EOG6K9BZS)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\dod     Drosophila simulans   Dsim\GD17528 Y   Drosophila sechellia   Dsec\GM23077 Y   Drosophila erecta   Dere\GG19723 Y   Drosophila yakuba   Dyak\GE17920 Y   Drosophila ananassae   Dana\GF22548 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA14299 Y   Drosophila persimilis   Dper\GL14862 Y   Drosophila willistoni   Dwil\GK10078 Y   Drosophila virilis   Dvir\GJ15247 Y   Drosophila mojavensis   Dmoj\GI15719 Y   Drosophila grimshawi   Dgri\GH24043 Y
Orthologs in non-Drosophila Dipterans (EOG6VDQ7V)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL009911   Anopheles gambiae Malaria mosquito  Agam\AGAP013475   Anopheles gambiae Malaria mosquito  Agam\AGAP004321   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015136
Orthologs in non-Dipteran Insects (EOG6WWQG2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\parv1   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG021416   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH24054   Atta cephalotes Leafcutter ant  Acep\ACEP20407   Camponotus floridanus Florida carpenter ant  Cflo\CFLO13435   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15098   Linepithema humile Argentine ant  Lhum\LH19381   Pogonomyrmex barbatus Red harvester ant  Pbar\PB11025   Acyrthosiphon pisum Pea aphid  Apim\ACYPI007002   Bombyx mori Silkmoth  Bmor\BGIBMGA010016   Pediculus humanus Human body louse  Phum\PHUM581480   Tribolium castaneum Red flour beetle  Tcas\TC003825
Orthologs in non-Insect Arthropods (EOG6ZKH3S)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_191361   Ixodes scapularis Deer tick  Isca\ISCW003422
Orthologs in non-Arthropod Metazoa (EOG67MDSX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\Y110A2AL.13   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016761gn   Danio rerio Zebrafish  Drer\ENSDARG00000089606   Xenopus tropicalis Western clawed frog  Xtro\pin1   Mus musculus House mouse  Mmus\Pin1   Rattus norvegicus Norway rat  Rnor\Pin1   Homo sapiens Human  Hsap\PIN1
Human Orthologs (1)
Gene OMIM HGNC Hsap\PIN1
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17528 Drosophila sechellia Dsec\GM23077 Drosophila erecta Dere\GG19723 Drosophila yakuba Dyak\GE17920 Drosophila ananassae Dana\GF22548 Drosophila pseudoobscura pseudoobscura Dpse\GA14299 Drosophila persimilis Dper\GL14862 Drosophila willistoni Dwil\GK10078 Drosophila virilis Dvir\GJ15247 Drosophila mojavensis Dmoj\GI15719 Drosophila grimshawi Dgri\GH24043
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	15677 y1 w67c23 P{EPgy2}dodEY03779
VDRC	v25210 w1118; P{GD9274}v25210 v25209 w1118; P{GD9274}v25209/CyO
Genomic Clones ( 2 )
	BACR09F10 BACR23I18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 31 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	SD16185
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH04430 GH25582 GM01407 GM25855 LD43142 LD47364 SD18920
Other clones	7176 7497 61308 104487 158502 bs77e03 Dmel_dig_003922_0693_3618 EC051400 EC051401 EC051431 EC052420 EC054380 EC054941 EK050502 EK125324 EK125623 EK186128 EK227864 EK261519 EK295203 FGM001H01 IP09060 UT01996
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0015379 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33111
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: dod CG17051 (Zhao, 1999.11)
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Transgenic flies (containing the vital gene fliI) carrying overlapping deficiencies that totally delete dod are viable and can fly. Loss of dod function is compensated for by a duplicate copy, by other unrelated proteins or by protein complexes that perform similar functions. (Maleszka et al., 1996) Defined as a transcription unit during the molecular analysis of the nearby fliI gene. (Campbell et al., 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078704 RefSeq (Proteins) • NP_523428 DDBJ / EMBL / GenBank • AAC28408 AAC46958 AAF50829 AF017777 AI406265 U35140 Z32455 Z83517 Entrez Gene - A searchable database of RefSeq genes. • 33111 UniProtKB/Swiss-Prot • P54353
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidyl-prolyl cis-trans isomerase, PpiC-type (IPR000297) WW domain (IPR001202) Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site (IPR023058)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59389 DroID - A comprehensive database of gene and protein interactions. • FBgn0015379 DRSC - Results from RNAi screens. • FBgn0015379 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015379 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17051-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0015379 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33111 Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /torstoll/dodo1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33111 modMine - Data generated by the modENCODE project. • FBgn0015379 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • P54353
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG17051 (Keleman et al., 2009.8.5, Cammarato et al., 2011) dod (Japanese National Institute of Genetics, 2012.5.21, Gurudatta et al., 2012) Pin1 (Yang et al., 2003, Freeman, 2001)
Name Synonym	dodo (Maleszka, 1995.8.31, Miklos et al., 1998, Maleszka et al., 1997, Maleszka et al., 1996, Campbell et al., 1993, Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 37 )
Generate a list of	All references relating to this gene ( 37 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 7 ) Review  ( 5 ) Personal communication to FlyBase  ( 6 ) Abstract  ( 3 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 2 ) Letter  ( 2 ) Stock list  ( 1 ) Curated genome annotation  ( 3 ) Protein sequence record  ( 1 )
Recent research papers ( 1 )
	Gurudatta et al., 2012, Dev. Biol. 369(1): 124--132 The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. [FBrf0219796] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...