l(3)j5E2, SR3-1
Ras pathway scaffolding protein - Ksr associates independently with Raf and Mek, and these interactions facilitate formation of a RAF/MEK complex thus promoting signaling through the Ras pathway
Please see the JBrowse view of Dmel\ksr for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
Gene model reviewed during 5.53
Antisense UTR: 3' UTR of long isoforms antisense to Hcs on opposite strand.
Gene model reviewed during 5.48
Gene model reviewed during 5.55
3.6 (northern blot)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ksr using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\ksr in GBrowse 23-47.5
P{lacW}1025 (at 82F8-10) maps to the left of P{lacW}ksrj5E2 (at 83A5-83A6).
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: ksr CG2899
Source for merge of: ksr l(3)j5E2
dsRNA made from templates generated with primers directed against this gene.
dsRNA has been made from templates generated with primers directed against this gene.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Overexpression of ksr blocks R7 photoreceptor cell formation in the eye.
ksr functions in multiple receptor tyrosine kinase pathways.