• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\α-Est10

General Information
Symbol	Dmel\α-Est10	Species	D. melanogaster
Name	α-Esterase-10	Annotation symbol	CG1131
Feature type	protein_coding_gene	FlyBase ID	FBgn0015569
Gene Model Status	Current	Stock availability	8 publicly available
Also Known As	αE10, alpha-Est10, α-Ests, DmαE10
Genomic Location
Chromosome (arm)	3R	Recombination map	3-
Cytogenetic map	84D8-84D9	Sequence location	3R:3,312,305..3,319,567 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene α-Esterase-10 is referred to in FlyBase by the symbol Dmel\α-Est10 (CG1131, FBgn0015569). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: carboxylesterase activity. There is experimental evidence that it is involved in the biological process: imaginal disc-derived wing morphogenesis. 8 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Carboxylesterase type B, active site; Carboxylesterase, type B. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval midgut, adult hindgut, adult heart, adult fat body, adult ovary, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626350_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of alpha-Est10. Gene sequence location is 3R:3312305..3319567.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02	Controlled Vocabulary Terms cellular_component
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 84D8-84D9   Limits computationally determined from genome sequence between P{EP}EP3060EP3060 and P{PZ}grn05930
Experimentally Determined Cytological Location
Cytogenetic map Notes References 84D8-84D10   (determined by in situ hybridisation)   (Ranz et al., 2001) 84D3-84D10     (Robin, 1996.3.11) 84D3-84D10   (determined by in situ hybridisation)   (Russell et al., 1996)
Experimentally Determined Recombination Data
Location	3- (Robin, 1996.3.11)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\α-Est10 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) α-Est10-RB FBtr0289953  NM_079533   2161   567 α-Est10-RC FBtr0305910  NM_001260033   2015   581 α-Est10-RD FBtr0305911  NM_001260034   1961   550
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein α-Est10-PB   FBpp0288391   64.1   567   7.54     NP_524257   AAG22202 α-Est10-PC   FBpp0297077   65.8   581   8.03     NP_001246962   AFH06281 α-Est10-PD   FBpp0297078   62.0   550   7.37     NP_001246963   AFH06282
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Carboxylesterase, type B (IPR002018) Carboxylesterase type B, active site (IPR019826)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAG22202   AE014297 AFH06281   AE014297 AFH06282   AX260182   BG639906   BT025819   CO156917   CO180115   CO269685   CO290346   CO296617   CO342520   EC059784   EC230808   EC236258   EC256061   EC261271   EL871061   EL871062   EL871298   EL871299   EW712917   U51054 AAB01153
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9I7L5 Q24204
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism | intense   (Campbell et al., 2003) first instar larval stage -- second instar larval stage   organism   (Campbell et al., 2003) third instar larval stage   organism | faint   (Campbell et al., 2003) pharate adult stage P8 -- P15   organism   (Campbell et al., 2003) day 1 of adulthood   organism | faint   (Campbell et al., 2003) adult head   (Campbell et al., 2003) day 5 of adulthood   organism | intense   (Campbell et al., 2003)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult crop, larval midgut, adult hindgut, adult heart, adult fat body, adult ovary, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    5.35 Larval Midgut    188.5 Larval Hindgut    51.1 Larval Malpighian Tubules    23.6 Larval Fat Body    29.4 Larval Salivary Gland    10.9 Larval Trachea    53.25 Larval Carcass    108.75 Adult Head    151.4 Adult Eye    71.35 Adult Brain    6 Adult Thoracic-Abdominal Ganglion    3.4 Adult Crop    463.3 Adult Midgut    61 Adult Hindgut    212 Adult Malpighian Tubules    13.2 Adult Fat Body    178.4 Adult Salivary Gland    20.1 Adult Heart    114.925 Adult VirginFemale Spermatheca    22.8 Adult InseminatedFemale Spermatheca    45.2 Adult Ovary    112.9 Adult Testis    117.8 Adult Male Accessory Gland    18.1 Adult Carcass    169.2 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    151.4   NA  Eye    71.35   NA  Brain    6   5.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3.4   NA  Crop    463.3   188.5  Midgut    61   51.1  Hindgut    212   23.6  Malpighian Tubules    no informative data   29.4  Fat Body    178.4   no informative data  Salivary Gland    no informative data   NA  Heart    114.925   53.25  Trachea    NA   NA  VirginFemale Spermatheca    22.8   NA  InseminatedFemale Spermatheca    45.2   NA  Ovary    112.9   NA  Testis    117.8   NA  Male Accessory Gland    18.1   108.75  Carcass    169.2 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    1 central nervous system, pupae P8    1 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    6 head, mated 1-day female    4 head, mated 4-day female    11 head, mated 20-day female    5 head, mated 1-day male    6 head, mated 4-day male    13 head, mated 20-day male    15 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    5 digestive system, 1-day adult    12 digestive system, 4-day adult    13 digestive system, 20-day adult    7 fat body, larvae L3 wandering    2 fat body, white prepupae    2 fat body, pupae P8    5 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    9 ovary, mated 4-day female    8 testis, mated 4-day male    9 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    5 embryo 14-16hr    14 embryo 16-18hr    17 embryo 18-20hr    4 embryo 20-22hr    4 embryo 22-24hr    4 larva L1    5 larva L2    15 larva L3 12hr old    11 larva L3 puffstage 1-2    5 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    5 white prepupae 24hr    4 pupae 2d postWPP    18 pupae 3d postWPP    10 pupae 4d postWPP    6 adult male 01day    13 adult male 05day    16 adult male 30day    13 adult female 01day    5 adult female 05day    7 adult female 30day    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    21 Schneider line 2 Sg4    6 embryonic 1182-4H    1 embryonic GM2    6 embryonic Kc167    1 embryonic S1    9 embryonic S3    17 leg disc CME L1    3 wing disc CME-W2    8 wing disc ML-DmD8    2 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    2 CNS ML-DmBG1-c1    4 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    12 ovary fGS/OSS    3 ovary OSC    5 ovary OSS    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    9 Cadmium 50 mM 6 hrs, larvae L3    8 Cadmium 50 mM 12 hrs, larvae L3    7 Cadmium 50 mM 48 hrs, 4-day adult    13 Cadmium 100 mM 48 hrs, 4-day adult    7 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    3 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    4 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    6 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    7 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    18 Rotenone 8 μg 12 hrs, larvae L3    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_10 mE1_20_mRNA_expression_cluster_11
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015569 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1131-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 α-Est10GD7266 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of α-Est10 Class Mutagen Stocks Known lesion α-Est10c00219 1 -- α-Est10CB-5238-3 1 -- α-Est10e01154 1 -- α-Est10EP3071 1 -- α-Est10MI04792 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of α-Est10 Class Mutagen Stocks Known lesion α-Est10GD7266 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes α-Est10KK106202 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes α-Est10NIG.1131R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6146 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}α-Est10EP3071 NA miscellaneous insertions Mi{MIC}α-Est10MI04792 NA P{RS3}α-Est10CB-5238-3 NA P{SUPor-P}KG02509 NA PBac{PB}α-Est10c00219 NA PBac{RB}α-Est10e01154 NA
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
	There is no information supporting a cellular component term for this gene. (Based on a review of available data on: 2012-12-21)
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
imaginal disc-derived wing morphogenesis inferred from mutant phenotype (Carreira et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
carboxylesterase activity inferred from biological aspect of ancestor with PANTHER:PTN000168392 (assigned by RefGenome) (Gaudet et al., 2010) inferred from sequence or structural similarity with EMBL:AF133341 (FlyBase, 1992-) non-traceable author statement (Robin, 1996.3.11)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions α-Est10 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0015569
Orthologs
OrthoDB Orthologs (138) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6960BD Dipteran inclusive ortholog search EOG6NP7BP Insect inclusive ortholog search EOG6VDNTX Arthropod inclusive ortholog search EOG6SF7N9 Metazoa inclusive ortholog search EOG683RXJ
Orthologs in Drosophila Species (EOG6960BD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\α-Est10     Drosophila simulans   Dsim\GD19481 Y   Drosophila sechellia   Dsec\GM10481 Y   Drosophila erecta   Dere\GG25183 Y   Drosophila yakuba   Dyak\GE25791 Y   Drosophila ananassae   Dana\GF17303 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10907 Y   Drosophila persimilis   Dper\GL12177 Y   Drosophila willistoni   Dwil\GK11082 Y   Drosophila virilis   Dvir\GJ10236 Y   Drosophila mojavensis   Dmoj\GI23482 Y   Drosophila grimshawi   Dgri\GH19276 Y
Orthologs in non-Drosophila Dipterans (EOG6NP7BP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL017071 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010389 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL015578 Y Anopheles gambiae Malaria mosquito  Agam\AGAP006228 Y Anopheles gambiae Malaria mosquito  Agam\AGAP006227 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ013918 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ013917 Y
Orthologs in non-Dipteran Insects (EOG6VDNTX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB43572 Y Apis mellifera Western honey bee  Amel\LOC409173 Y Apis mellifera Western honey bee  Amel\LOC406105 Y Apis mellifera Western honey bee  Amel\LOC409171 Y Apis mellifera Western honey bee  Amel\LOC411223 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016110 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013528 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG001008 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016111 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013527 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007160 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016419 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016108 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG009500 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016107 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG001007 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18551 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH26243 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11542 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11540 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11541 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17355 Y Atta cephalotes Leafcutter ant  Acep\ACEP13105 Y Atta cephalotes Leafcutter ant  Acep\ACEP13104 Y Atta cephalotes Leafcutter ant  Acep\ACEP25685 Y Atta cephalotes Leafcutter ant  Acep\ACEP18169 Y Atta cephalotes Leafcutter ant  Acep\ACEP15049 Y Atta cephalotes Leafcutter ant  Acep\ACEP18168 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17278 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17282 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14727 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17277 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17283 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17279 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17281 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17376 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15046 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14885 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14886 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20516 Y Linepithema humile Argentine ant  Lhum\LH13767 Y Linepithema humile Argentine ant  Lhum\LH13028 Y Linepithema humile Argentine ant  Lhum\LH13030 Y Linepithema humile Argentine ant  Lhum\LH13031 Y Linepithema humile Argentine ant  Lhum\LH25422 Y Linepithema humile Argentine ant  Lhum\LH25421 Y Linepithema humile Argentine ant  Lhum\LH14213 Y Linepithema humile Argentine ant  Lhum\LH13032 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14106 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB13183 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB10145 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB10594 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14381 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB13537 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB11941 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB15739 Y Solenopsis invicta Red fire ant  Sinv\SINV17793 Y Solenopsis invicta Red fire ant  Sinv\SINV24741 Y Solenopsis invicta Red fire ant  Sinv\SINV15933 Y Solenopsis invicta Red fire ant  Sinv\SINV17845 Y Solenopsis invicta Red fire ant  Sinv\SINV10037 Y Solenopsis invicta Red fire ant  Sinv\SINV12025 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005798 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI006535 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI004350 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI006110 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001922 Y Bombyx mori Silkmoth  Bmor\BGIBMGA004934 Y Bombyx mori Silkmoth  Bmor\BGIBMGA010986 Y Bombyx mori Silkmoth  Bmor\BGIBMGA004684 Y Bombyx mori Silkmoth  Bmor\BGIBMGA010976 Y Bombyx mori Silkmoth  Bmor\Bmo.10485 Y Bombyx mori Silkmoth  Bmor\BGIBMGA014599 Y Bombyx mori Silkmoth  Bmor\BGIBMGA011218 Y Pediculus humanus Human body louse  Phum\PHUM569560 Y Pediculus humanus Human body louse  Phum\PHUM463960 Y Pediculus humanus Human body louse  Phum\PHUM136220 Y Pediculus humanus Human body louse  Phum\PHUM586140 Y Tribolium castaneum Red flour beetle  Tcas\TC006732 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15229 Y Tribolium castaneum Red flour beetle  Tcas\TC009697 Y Tribolium castaneum Red flour beetle  Tcas\GLEAN_15230 Y Tribolium castaneum Red flour beetle  Tcas\TC000804 Y Tribolium castaneum Red flour beetle  Tcas\TC009692 Y Tribolium castaneum Red flour beetle  Tcas\TC009691 Y Tribolium castaneum Red flour beetle  Tcas\TC009690 Y Tribolium castaneum Red flour beetle  Tcas\TC009698 Y Tribolium castaneum Red flour beetle  Tcas\TC009693 Y Tribolium castaneum Red flour beetle  Tcas\TC009694 Y Tribolium castaneum Red flour beetle  Tcas\TC009699 Y Tribolium castaneum Red flour beetle  Tcas\TC000803 Y Tribolium castaneum Red flour beetle  Tcas\TC012856 Y Tribolium castaneum Red flour beetle  Tcas\TC009696 Y Tribolium castaneum Red flour beetle  Tcas\TC005499 Y Tribolium castaneum Red flour beetle  Tcas\TC015226 Y Tribolium castaneum Red flour beetle  Tcas\TC006733 Y Tribolium castaneum Red flour beetle  Tcas\TC015225 Y
Orthologs in non-Insect Arthropods (EOG6SF7N9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\tub2 Y Ixodes scapularis Deer tick  Isca\ISCW003278 Y Ixodes scapularis Deer tick  Isca\ISCW009205 Y Ixodes scapularis Deer tick  Isca\ISCW020819 Y Ixodes scapularis Deer tick  Isca\ISCW022246 Y Ixodes scapularis Deer tick  Isca\ISCW001132 Y Ixodes scapularis Deer tick  Isca\ISCW020830 Y Ixodes scapularis Deer tick  Isca\ISCW021542 Y Ixodes scapularis Deer tick  Isca\ISCW013353 Y Ixodes scapularis Deer tick  Isca\ISCW003637 Y Ixodes scapularis Deer tick  Isca\ISCW006896 Y Ixodes scapularis Deer tick  Isca\ISCW006617 Y Ixodes scapularis Deer tick  Isca\ISCW022251 Y Ixodes scapularis Deer tick  Isca\ISCW024395 Y Ixodes scapularis Deer tick  Isca\ISCW024484 Y Ixodes scapularis Deer tick  Isca\ISCW021541 Y Ixodes scapularis Deer tick  Isca\ISCW004315 Y Ixodes scapularis Deer tick  Isca\ISCW022244 Y Ixodes scapularis Deer tick  Isca\ISCW023611 Y Ixodes scapularis Deer tick  Isca\ISCW006205 Y Ixodes scapularis Deer tick  Isca\ISCW001748 Y
Orthologs in non-Arthropod Metazoa (EOG683RXJ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Rattus norvegicus Norway rat  Rnor\Ces2j Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD19481 Drosophila sechellia Dsec\GM10481 Drosophila erecta Dere\GG25183 Drosophila yakuba Dyak\GE25791 Drosophila ananassae Dana\GF17303 Drosophila pseudoobscura pseudoobscura Dpse\GA10907 Drosophila persimilis Dper\GL12177 Drosophila willistoni Dwil\GK11082 Drosophila virilis Dvir\GJ10236 Drosophila mojavensis Dmoj\GI23482 Drosophila grimshawi Dgri\GH19276
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	17086 w1118; P{EP}α-Est10EP3071 38055 y1 w*; Mi{MIC}α-Est10MI04792
Harvard	- PBac{PB}α-Est10c00219 - PBac{RB}α-Est10e01154
Kyoto	123523 w1118; P{RS3}α-Est10CB-5238-3
VDRC	v107917 P{KK106202}VIE-260B v18048 w1118; P{GD7266}v18048 v18050 w1118; P{GD7266}v18050
Genomic Clones ( 1 )
	BACR06G09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 13 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP03520
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	81218 CK01.94D.C10 DMG1-chr3R.4.039.a EC00937 EK073743 EK095536 EK214433 EN09551 EP15045 IP03220 IP03420 SD08237
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0015569 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40896
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: α-Est10 CG1131 (Milshina, 1999.11)
Source for database merge of	Source for merge of: α-Est10 anon-WO0172774.144 (FlyBase, 1996-)
Additional comments	Source for merge of α-Est10 anon-WO0172774.144 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Eleven putative esterase genes from the region containing the α-esterase cluster are cloned. (Russell et al., 1996)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079533 NM_001260033 NM_001260034 RefSeq (Proteins) • NP_524257 NP_001246962 NP_001246963 DDBJ / EMBL / GenBank • AAB01153 AAG22202 AFH06281 AFH06282 AX260182 U51054 Entrez Gene - A searchable database of RefSeq genes. • 40896 UniProtKB/TrEMBL • Q9I7L5 Q24204
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Carboxylesterase, type B (IPR002018) Carboxylesterase type B, active site (IPR019826)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0015569 DRSC - Results from RNAi screens. • FBgn0015569 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015569 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1131-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0015569 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40896 modMine - Data generated by the modENCODE project. • FBgn0015569
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	aE10 (Robin, 1996.3.11) alpha-Est10 (Izutsu et al., 2012, Bellen et al., 2011, Japanese National Institute of Genetics, 2012.5.21) anon-WO0172774.144   CG1131 (Keleman et al., 2009.8.5) DmαE10 (de Q. Robin et al., 2000, Campbell et al., 2003) Esterase-10 (Edwards et al., 2006) K (Robin et al., 1996) unnamed (Russell et al., 1996) αE10 (de Q. Robin et al., 2000, Robin et al., 1996, de Q. Robin et al., 2000, Campbell et al., 2003) α-Est10 (Fernández-Ayala et al., 2010, Carreira et al., 2011) α-Ests (Ranz et al., 2001, Ranz et al., 2001)
Name Synonym	Esterase-10 (Edwards et al., 2006, Edwards et al., 2009) fragment K (Robin et al., 1996) α-Esterase-10
Secondary FlyBase IDs
	FBgn0046454
References ( 33 )
Generate a list of	All references relating to this gene ( 33 )
List References by type	Research paper  ( 12 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 4 ) DNA/RNA sequence record  ( 1 ) Stock list  ( 1 ) Curated genome annotation  ( 2 ) Website  ( 1 ) Patent  ( 1 )
Recent research papers ( 3 )
	Izutsu et al., 2012, PLoS ONE 7(3): e33288 Genome features of "dark-fly", a Drosophila line reared long-term in a dark environment. [FBrf0217825] Bellen et al., 2011, Genetics 188(3): 731--743 The Drosophila gene disruption project: progress using transposons with distinctive site specificities. [FBrf0214229] Carreira et al., 2011, BMC Dev. Biol. 11: 32 Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273] Show all research papers ...