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Gene Dmel\Acp29AB

General Information
Symbol	Dmel\Acp29AB	Species	D. melanogaster
Name	Accessory gland protein 29AB	Annotation symbol	CG17797
Feature type	protein_coding_gene	FlyBase ID	FBgn0015583
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	29C1-29C1	Sequence location	2L:8,392,456..8,393,222 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Accessory gland protein 29AB is referred to in FlyBase by the symbol Dmel\Acp29AB (CG17797, FBgn0015583). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: galactose binding; carbohydrate binding. There is experimental evidence that it is involved in the biological process: sperm competition; multicellular organism reproduction; sperm storage. 45 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: C-type lectin; C-type lectin fold; C-type lectin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1624840_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Acp29AB. Gene sequence location is 2L:8392456..8393222.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 29C1-29C1   Limits computationally determined from genome sequence between P{lacW}l(2)k12914k12914&P{lacW}Akap200k07118a and P{lacW}l(2)k03706k03706&P{lacW}Acerk07704
Experimentally Determined Cytological Location
Cytogenetic map Notes References 29C1-29C5     (Celniker, 1998.3.17) 29A-29B     (Aguade, 1999.2.19) 29A-29B   (determined by in situ hybridisation)   (Wolfner et al., 1997) 29B-29B   (determined by in situ hybridisation)   (Clark et al., 1995)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Acp29AB for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Acp29AB-RA FBtr0079716  NM_078788   767   234
Additional Transcript Data & Comments
Reported size (kB)	0.95 (northern blot) (Wolfner et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Acp29AB-PA   FBpp0079321   27.2   234   7.96     NP_523512   AAF52665
Additional Polypeptide Data & Comments
Reported size (kDa)	234 (aa) (Wolfner et al., 1997)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • C-type lectin (IPR001304) C-type lectin-like (IPR016186) C-type lectin fold (IPR016187)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF52665   AC004423   AJ240513 CAB53187   AJ240514 CAB53188   AJ240515 CAB53189   AJ240516 CAB53190   AJ240517 CAB53191   AJ240518 CAB53192   AJ240519 CAB53193   AJ240520 CAB53194   AJ240521 CAB53195   AJ240522 CAB53196   AJ240523 CAB53197   AJ240524 CAB53198   AJ240525 CAB53199   AJ240526 CAB53200   AJ240527 CAB53201   AJ240528 CAB53202   AJ240529 CAB53203   AJ240530 CAB53204   AJ240531 CAB53205   AJ240532 CAB53206   AJ240533 CAB53207   AJ240534 CAB53208   AJ240535 CAB53209   AJ240536 CAB53210   AJ240537 CAB53211   AJ240538 CAB53212   AJ240539 CAB53213   AJ240540 CAB53214   AJ240541 CAB53215   AJ240542 CAB53216   AJ240543 CAB53217   AJ240544 CAB53218   AJ240545 CAB53219   AJ240546 CAB53220   AJ240547 CAB53221   AJ240548 CAB53222   AJ240549 CAB53223   AJ240550 CAB53224   AJ240551 CAB53225   AY010527 AAG32559   AY010528 AAG32560   AY010529 AAG32561   AY010530 AAG32562   AY010531 AAG32563   AY010532 AAG32564   AY010533 AAG32565   AY010534 AAG32566   AY010535 AAG32567   AY010536 AAG32568   AY010537 AAG32569   AY010538 AAG32570   AY010539 AAG32571   AY010540 AAG32572   AY010541 AAG32573   AY010542 AAG32574   AY010543 AAG32575   AY344305 AAR05024   AY344306 AAR05025   AY344307 AAR05026   AY344308 AAR05027   AY344309 AAR05028   AY344310 AAR05029   AY344311 AAR05030   AY344312 AAR05031   AY344313 AAR05032   AY344314 AAR05033   AY344315 AAR05034   AY344316 AAR05035   AY344317 AAR05036   AY344318 AAR05037   AY344319 AAR05038   AY344320 AAR05039   AY344321 AAR05040   AY344322 AAR05041   AY344323 AAR05042   AY344324 AAR05043   AY635210 AAT49116   AY635211 AAT49117   AY635212 AAT49118   AY635213 AAT49119   AY635214 AAT49120   AY635215 AAT49121   AY635216 AAT49122   AY635217 AAT49123   BT088801   EL869986   EL869987   EL869988   EL869989   EL869990   EL869991   U85758 AAB96382
UniProtKB/Swiss-Prot	O46197
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference adult stage | male   male accessory gland main cell   (Wolfner et al., 1997) male accessory gland   (Wolfner et al., 1997)
Additional Descriptive Data
	Expressed at high levels in male accessory gland main cells; not clear if transcript is expressed in secondary cells. (Wolfner et al., 1997)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
extracellular space inferred from direct assay (Findlay et al., 2008)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland    7857.5 Adult Carcass    19.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland  (7857.5) Adult Carcass    19.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland  (7857.5) Adult Carcass    19.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland    7857.5 Adult Carcass    19.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland    7857.5 Adult Carcass    19.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland  (7857.5) Adult Carcass    19.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland  (7857.5) Adult Carcass    19.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    6.85 Larval Midgut    6.3 Larval Hindgut    3.9 Larval Malpighian Tubules    5 Larval Fat Body    2.9 Larval Salivary Gland    3 Larval Trachea    6.025 Larval Carcass    3.175 Adult Head    2.8 Adult Eye    2.35 Adult Brain    4.6 Adult Thoracic-Abdominal Ganglion    3.6 Adult Crop    7.6 Adult Midgut    2.1 Adult Hindgut    5 Adult Malpighian Tubules    4.5 Adult Fat Body    9.9 Adult Salivary Gland    22.4 Adult Heart    4.45 Adult VirginFemale Spermatheca    7.4 Adult InseminatedFemale Spermatheca    10 Adult Ovary    3.7 Adult Testis    16.3 Adult Male Accessory Gland    7857.5 Adult Carcass    19.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2.8   NA  Eye    2.35   NA  Brain    4.6   6.85  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3.6   NA  Crop    7.6   6.3  Midgut    2.1   3.9  Hindgut    5   5  Malpighian Tubules    4.5   2.9  Fat Body    9.9   3  Salivary Gland    no informative data   NA  Heart    4.45   6.025  Trachea    NA   NA  VirginFemale Spermatheca    7.4   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    3.7   NA  Testis    no informative data   NA  Male Accessory Gland    7857.5   3.175  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male    392 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male    392 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male    392 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male  (392) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    3 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    0 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    16 accessory gland, mated 4-day male    392 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    40 adult male 05day    42 adult male 30day    33 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day  (40) adult male 05day  (42) adult male 30day  (33) adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    40 adult male 05day    42 adult male 30day    33 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    40 adult male 05day    42 adult male 30day    33 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    40 adult male 05day    42 adult male 30day    33 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day  (40) adult male 05day  (42) adult male 30day  (33) adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    40 adult male 05day    42 adult male 30day    33 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    0 embryo 22-24hr    0 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    40 adult male 05day    42 adult male 30day    33 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    1 cold shock, 4-day adult    1 heat shock, 4-day adult    3 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    1 Cadmium 100 mM 48 hrs, 4-day adult    0 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    11 Ethanol 2.5% 3 hrs, larvae L3    4 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    0 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    5 Paraquat 10 mM 48 hrs, 4-day adult    3 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (Graveley et al., 2011) mE1_20_mRNA_expression_cluster_20
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015583 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17797-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 Acp29ABGD5362 viable, with Scer\GAL4hs.PB Acp29ABScer\UAS.cLa viable, with Scer\GAL4αTub84B.PL Acp29ABScer\UAS.cLa Sterility Allele fertile (with Df(2L)ED611) Acp29ABW1 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 Acp29ABGD5362 Phenotype manifest in Allele trichogen cell, with Scer\GAL4pnr-MD237 Acp29ABGD5362
Classical Alleles ( 42 )
For All Classical Alleles Show
Allele of Acp29AB Class Mutagen Stocks Known lesion Acp29AB1 0 -- Acp29AB2 0 -- Acp29ABLa13 natural population 0 -- Acp29ABLa14 natural population 0 -- Acp29ABLa15 natural population 0 -- Acp29ABLa16 natural population 0 -- Acp29ABLa1 natural population 0 -- Acp29ABLa21 natural population 0 -- Acp29ABLa25 natural population 0 -- Acp29ABLa34 natural population 0 -- Acp29ABLa35 natural population 0 -- Acp29ABLa3 natural population 0 -- Acp29ABLa4 natural population 0 -- Acp29ABLa5 natural population 0 -- Acp29ABLa6 natural population 0 -- Acp29ABLa9 natural population 0 -- Acp29ABMa13 natural population 0 -- Acp29ABMa18 natural population 0 -- Acp29ABMa20 natural population 0 -- Acp29ABMa21 natural population 0 -- Acp29ABMa43 natural population 0 -- Acp29ABMa45 natural population 0 -- Acp29ABMa48 natural population 0 -- Acp29ABMa50 natural population 0 -- Acp29ABMa52 natural population 0 -- Acp29ABMa5 natural population 0 -- Acp29ABMa67 natural population 0 -- Acp29ABMa7 natural population 0 -- Acp29ABMa8 natural population 0 -- Acp29ABMo15b natural population 0 -- Acp29ABMo1b natural population 0 -- Acp29ABMo2b natural population 0 -- Acp29ABMo34a natural population 0 -- Acp29ABMo36a natural population 0 -- Acp29ABMo37a natural population 0 -- Acp29ABMo40b natural population 0 -- Acp29ABMo47a natural population 0 -- Acp29ABMo52b natural population 0 -- Acp29ABMo58b natural population 0 -- Acp29ABMo80b natural population 0 -- Acp29ABMo8b natural population 0 -- Acp29ABW1 ethyl methanesulfonate 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Acp29AB Class Mutagen Stocks Known lesion Acp29ABGD5362 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Acp29ABKK106504 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Acp29ABScer\UAS.cLa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5362} NA P{KK106504} NA P{UAS-Acp29AB.L} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 10 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
multicellular organism reproduction inferred from expression pattern (Findlay et al., 2008, Mueller et al., 2005) sperm competition inferred from mutant phenotype (Wong et al., 2008) sperm storage inferred from mutant phenotype (Wong et al., 2008)
Cellular Component
CV term Evidence References
extracellular space inferred from direct assay (Findlay et al., 2008)
Terms Based on Predictions or Assertions ( 8 terms )
Molecular Function
CV term Evidence References
carbohydrate binding inferred from sequence or structural similarity (Mueller et al., 2004) inferred from sequence or structural similarity with Lectin-galC1 (Tanji et al., 2006) galactose binding inferred from sequence or structural similarity (Theopold et al., 1999) hormone activity non-traceable author statement (FlyBase, 1992-)
Biological Process
CV term Evidence References
post-mating behavior non-traceable author statement (Swiss-Prot Project Members, 2000.10.1) sperm competition traceable author statement (Chapman, 2001) sperm displacement non-traceable author statement (FlyBase, 1992-)
Cellular Component
CV term Evidence References
extracellular region non-traceable author statement (FlyBase, 1992-) extracellular space inferred from sequence model (Mueller et al., 2005)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Acp29AB allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60286 DroID - A comprehensive database of gene and protein interactions. • FBgn0015583 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34162
Orthologs
OrthoDB Orthologs (8) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG634WSD Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search EOG615V8B
Orthologs in Drosophila Species (EOG634WSD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Acp29AB     Drosophila simulans   Dsim\Acp29AB Y   Drosophila sechellia   Dsec\Acp29AB Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (EOG615V8B)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Danio rerio Zebrafish  Drer\ENSDARG00000092391 Y Mus musculus House mouse  Mmus\Klri2 Y Mus musculus House mouse  Mmus\Klri1 Y Rattus norvegicus Norway rat  Rnor\Klri2 Y Rattus norvegicus Norway rat  Rnor\ENSRNOG00000037064 Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (3) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\Acp29AB Drosophila sechellia Dsec\Acp29AB Drosophila ananassae Dana\GF15345
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v100995 P{KK106504}VIE-260B v41210 w1118; P{GD5362}v41210/TM3 v41211 w1118; P{GD5362}v41211/TM3
Genomic Clones ( 2 )
	BACR02I15 BACR15P08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 4 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	IP02113
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	IP02114 IP02115 IP02116
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0015583 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34162
Antibody Information
	polyclonal (Wong et al., 2008)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Acp29AB CG17797 (Theopold, 2000.7.21)
Source for database merge of
Additional comments
Other Comments
	Acp29AB is required for the normal maintenance of sperm in storage. (Wong et al., 2008) Isolated in a screen for seminal fluid proteins. (Mueller et al., 2004) Gene is identified in a differential cDNA hybridisation screen. (Wolfner et al., 1997) If females remate frequently relative to the duration of sperm storage and rate of sperm use, sperm displacement may be an important component of male reproductive success. Significant association has been found between Acp29AB mutant male sperm and the ability to resist displacement by subsequent sperm. There is no correlation between the ability to displace resident sperm and the ability to resist being displaced by subsequent sperm, this lack of correlation suggests that different mechanisms mediate that the two components of sperm displacement. (Clark et al., 1995) May promote replacement of sperm already stored by a female.
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078788 RefSeq (Proteins) • NP_523512 DDBJ / EMBL / GenBank • AAB96382 AAF52665 AAG32559 AAG32560 AAG32561 AAG32562 AAG32563 AAG32564 AAG32565 AAG32566 AAG32567 AAG32568 AAG32569 AAG32570 AAG32571 AAG32572 AAG32573 AAG32574 AAG32575 AAR05024 AAR05025 AAR05026 AAR05027 AAR05028 AAR05029 AAR05030 AAR05031 AAR05032 AAR05033 AAR05034 AAR05035 AAR05036 AAR05037 AAR05038 AAR05039 AAR05040 AAR05041 AAR05042 AAR05043 AAT49116 AAT49117 AAT49118 AAT49119 AAT49120 AAT49121 AAT49122 AAT49123 AC004423 AJ240513 AJ240514 AJ240515 AJ240516 AJ240517 AJ240518 AJ240519 AJ240520 AJ240521 AJ240522 AJ240523 AJ240524 AJ240525 AJ240526 AJ240527 AJ240528 AJ240529 AJ240530 AJ240531 AJ240532 AJ240533 AJ240534 AJ240535 AJ240536 AJ240537 AJ240538 AJ240539 AJ240540 AJ240541 AJ240542 AJ240543 AJ240544 AJ240545 AJ240546 AJ240547 AJ240548 AJ240549 AJ240550 AJ240551 AY010527 AY010528 AY010529 AY010530 AY010531 AY010532 AY010533 AY010534 AY010535 AY010536 AY010537 AY010538 AY010539 AY010540 AY010541 AY010542 AY010543 AY344305 AY344306 AY344307 AY344308 AY344309 AY344310 AY344311 AY344312 AY344313 AY344314 AY344315 AY344316 AY344317 AY344318 AY344319 AY344320 AY344321 AY344322 AY344323 AY344324 AY635210 AY635211 AY635212 AY635213 AY635214 AY635215 AY635216 AY635217 CAB53187 CAB53188 CAB53189 CAB53190 CAB53191 CAB53192 CAB53193 CAB53194 CAB53195 CAB53196 CAB53197 CAB53198 CAB53199 CAB53200 CAB53201 CAB53202 CAB53203 CAB53204 CAB53205 CAB53206 CAB53207 CAB53208 CAB53209 CAB53210 CAB53211 CAB53212 CAB53213 CAB53214 CAB53215 CAB53216 CAB53217 CAB53218 CAB53219 CAB53220 CAB53221 CAB53222 CAB53223 CAB53224 CAB53225 U85758 Entrez Gene - A searchable database of RefSeq genes. • 34162 UniProtKB/Swiss-Prot • O46197
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • C-type lectin (IPR001304) C-type lectin-like (IPR016186) C-type lectin fold (IPR016187)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60286 DroID - A comprehensive database of gene and protein interactions. • FBgn0015583 DRSC - Results from RNAi screens. • FBgn0015583 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015583 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17797-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0015583 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34162 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34162 modMine - Data generated by the modENCODE project. • FBgn0015583
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	AC004423b (Theopold, 2000.7.21) AC 004423B (Theopold et al., 1999) Acp29 (Zurovcova et al., 2006) Acp29AB (Swiss-Prot Project Members, 2000.10.1, Zurovcova et al., 2006, Ravi Ram and Wolfner, 2007, Lai et al., 2007, Mueller et al., 2007, Tanji et al., 2006, Panhuis et al., 2003, Wagstaff and Begun, 2005, McGraw et al., 2008, Wong et al., 2008, Takemori and Yamamoto, 2009, Sousa-Neves and Rosas, 2010, Ravi Ram and Wolfner, 2007) Acp29AB-II (Wijffels et al., 2001) Acp29B (Clark et al., 1995, ) CG17797 (Mueller et al., 2005, Keleman et al., 2009.8.5)
Name Synonym	accessory gland protein (Theopold, 2000.7.21) Accessory gland protein 29AB (Wolfner et al., 1997, ) Accessory gland-specific peptide 29AB (Takemori and Yamamoto, 2009, )
Secondary FlyBase IDs
References ( 58 )
Generate a list of	All references relating to this gene ( 58 )
List References by type	Research paper  ( 30 ) Supplementary material  ( 5 ) Review  ( 6 ) Personal communication to FlyBase  ( 3 ) Abstract  ( 4 ) FlyBase analysis  ( 2 ) Protein sequence record  ( 2 ) DNA/RNA sequence record  ( 2 ) Curated genome annotation  ( 2 ) Letter  ( 1 )
Recent research papers ( 3 )
	Zhang et al., 2013, Mol. Ecol. 22(5): 1400--1415 Natural genetic variation in male reproductive genes contributes to nontransitivity of sperm competitive ability in Drosophila melanogaster. [FBrf0220937] Dottorini et al., 2011, BMC Bioinformatics 12: 34 Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. [FBrf0214379] Yang et al., 2011, G3 (Bethesda) 1(6): 427--436 Partitioning transcript variation in Drosophila: abundance, isoforms, and alleles. [FBrf0217638] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...