Gene model reviewed during 5.41
Gene model reviewed during 5.49
Composed of a catalytic subunit (A) and a regulatory subunit (B) (By similarity). Interacts with sra.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CanB2 using the Feature Mapper tool.
CanB and CanB2 have over 98% amino acid identity. A CanB2 probe detects two transcripts, 2.3 and 1.6 kb, in Northern blots of pupal, larval, and adult stages. The genomic sequence of CanB2 is consistent with its being the 1.6 kb transcript, but further evidence is necessary. The 1.6 kb transcript is found in pupal, larval, and adult stages, with highest levels in in whole adults and adult heads. The 2.3 kb transcript is found in all developmental stages examined, with lower levels in larvae and early pupae.
GBrowse - Visual display of RNA-Seq signalsView Dmel\CanB2 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
5 alleles of "CS2-1" have been isolated.