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Gene Dmel\Trip1

General Information
Symbol	Dmel\Trip1	Species	D. melanogaster
Name	Trip1	Annotation symbol	CG8882
Feature type	protein_coding_gene	FlyBase ID	FBgn0015834
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	eIF3-S2
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	25B5-25B5	Sequence location	2L:4,966,367..4,967,778 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Trip1 is referred to in FlyBase by the symbol Dmel\Trip1 (CG8882, FBgn0015834). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process: translation; translational initiation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Very high expression at all stages of development. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1630519_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Trip1. Gene sequence location is 2L:4966367..4967778.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Dekanty et al., 2010, PLoS Genet. 6(6): e1000994 Sequence features BKN46519 HFA03464 BKN27698
FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 22 of adulthood day 20 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 25B5-25B5   Limits computationally determined from genome sequence between P{lacW}l(2)k10004k10004&P{EP}CG3036EP963 and P{PZ}l(2)0571405714
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Trip1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Trip1-RA FBtr0079053  NM_078754   1180   326
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Trip1-PA   FBpp0078689   36.2   326   4.97     NP_523478   AAF52183
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • WD40/YVTN repeat-like-containing domain (IPR015943) WD40-repeat-containing domain (IPR017986) WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) WD40 repeat, conserved site (IPR019775) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246882   AA263308   AA264074   AA439539   AA440833   AA536221   AA540747   AA541043   AA567052   AA567278   AA694771   AA695803   AA735302   AA735975   AA802193   AA802221   AA803151   AA820342   AA820418   AA820510   AA820608   AA940926   AA941199   AA941902   AA951911   AA951964   AA990670   AE014134 AAF52183   AI061796   AI063959   AI064463   AI134017   AI238319   AI257249   AI260047   AI296353   AI387718   AI387815   AI401940   AI405052   AI405948   AI455192   AI456569   AI514547   AI515502   AI516635   AI516777   AI520488   AI544089   AI546203   AW942693   AY118527 AAM49896   AY232199   AY432865   BE977777   BF485735   BF499675   BF504166   BG632794   BG639092   BH840669   BI142178   BI167703   BI170890   BI172533   BI216234   BI216857   BI229479   BI231625   BI234809   BI237464   BI240168   BI241841   BI354231   BI354341   BI358517   BI358702   BI362597   BI362847   BI367010   BI372028   BI374637   BI375299   BI375366   BI483705   BI483715   BI484739   BI484892   BI485050   BI485087   BI485095   BI485523   BI485897   BI564636   BI565044   BI566334   BI566741   BI566879   BI568167   BI571639   BI576849   BI577753   BI577985   BI578094   BI578605   BI579218   BI580277   BI581011   BI581012   BI582472   BI583436   BI584165   BI584739   BI585745   BI585995   BI586544   BI587100   BI587419   BI587578   BI587713   BI587889   BI590227   BI591991   BI592140   BI592414   BI592673   BI592839   BI605021   BI605091   BI605498   BI606218   BI606513   BI607195   BI607364   BI607608   BI608167   BI608336   BI608391   BI609471   BI609749   BI610436   BI610680   BI612579   BI612793   BI616537   BI616656   BI616892   BI617286   BI618835   BI619157   BI619909   BI619940   BI620509   BI621244   BI621941   BI622120   BI622410   BI623048   BI623980   BI625863   BI628411   BI629347   BI629737   BI629944   BI631045   BI631242   BI631363   BI633738   BI634980   BI635086   BI635250   BI635937   BI638956   BI639951   BI640929   BI641852   BP540988   BP540989   BP544716   BP544717   BP546205   BP549584   BP549585   BP549663   BP549664   BP549773   BP549774   BP555879   BP555880   BQ103442   BX049449   CK604805   CK604806   CK658469   CK662331   CO154895   CO155952   CO156400   CO178198   CO180495   CO278230   CO285533   CO291686   CO298205   CO305548   CO335688   CO337124   EC057185   EC074093   EC077388   EC210003   EC218573   EC230978   EC246931   EC264261   EL886370   EL886700   EL886759   EV577842   EV578672   EV578856   EV588229   GH748486   GH751055   GH751207   GH751693   GH752073   GH754646   GH755530   GH757800   GH759170   GH770259   GH772135   GH777682   GH778871   GH778881   GH779044   GH779972   GH785506   GH786309   GH787089   GH788576   GH789132   GH790937   GH792320   GH796145   GH796642   GH800577   GH808186   GH809952   GH810007   GH812424   GH812465   GH812686   GH814864   GH815001   GH815126   GH817078   GH819105   GH819388   GH825675   GH826900   GH827242   GH829584   GH830403   GH831128   GH831406   GH837070   GH847152   GH852325   GH852801   GH853566   GH853829   GH856778   GH860335   GH861693   GH862952   GH863150   GH863760   GH864141   GH865081   GH865482   GH875744   GH876395   GH877760   GH882472   GH882595   GH884918   GH887227   GH889351   GH891931   GH895181   GH896695   GH896732   GH898409   GH900101   GH900228   GH900509   GH900611   GH908713   GH910594   GH912370   GH916082   GH916290   GH916767   GH917166   GH917267   GH919252   GH919425   GH922916   GH923022   GH924656   GH924669   GH928397   GH930892   GH931817   GH932325   GH932642   GH936325   GH937465   GH940119   U90930 AAB53431
UniProtKB/Swiss-Prot	O02195
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0015834    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0015834 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Very high expression at all stages of development. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0015834 expression level Developmental Stage   Expression Level embryo 00-02hr    28149 embryo 02-04hr    43769 embryo 04-06hr    43015 embryo 06-08hr    37078 embryo 08-10hr    38491 embryo 10-12hr    35468 embryo 12-14hr    23385 embryo 14-16hr    25646 embryo 16-18hr    19740 embryo 18-20hr    16882 embryo 20-22hr    16618 embryo 22-24hr    15787 larva L1    28424 larva L2    22736 larva L3 12hr old    15710 larva L3 puffstage 1-2    15488 larva L3 puffstage 3-6    16804 larva L3 puffstage 7-9    19004 white prepupae new    18480 white prepupae 12hr    18080 white prepupae 24hr    19650 pupae 2d postWPP    15590 pupae 3d postWPP    10283 pupae 4d postWPP    10377 adult male 01day    10272 adult male 05day    11638 adult male 30day    12163 adult female 01day    24120 adult female 05day    22835 adult female 30day    23663 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (28149) embryo 02-04hr  (43769) embryo 04-06hr  (43015) embryo 06-08hr  (37078) embryo 08-10hr  (38491) embryo 10-12hr  (35468) embryo 12-14hr  (23385) embryo 14-16hr  (25646) embryo 16-18hr  (19740) embryo 18-20hr  (16882) embryo 20-22hr  (16618) embryo 22-24hr  (15787) larva L1  (28424) larva L2  (22736) larva L3 12hr old  (15710) larva L3 puffstage 1-2  (15488) larva L3 puffstage 3-6  (16804) larva L3 puffstage 7-9  (19004) white prepupae new  (18480) white prepupae 12hr  (18080) white prepupae 24hr  (19650) pupae 2d postWPP  (15590) pupae 3d postWPP  (10283) pupae 4d postWPP  (10377) adult male 01day  (10272) adult male 05day  (11638) adult male 30day  (12163) adult female 01day  (24120) adult female 05day  (22835) adult female 30day  (23663) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (28149) embryo 02-04hr  (43769) embryo 04-06hr  (43015) embryo 06-08hr  (37078) embryo 08-10hr  (38491) embryo 10-12hr  (35468) embryo 12-14hr  (23385) embryo 14-16hr  (25646) embryo 16-18hr  (19740) embryo 18-20hr  (16882) embryo 20-22hr  (16618) embryo 22-24hr  (15787) larva L1  (28424) larva L2  (22736) larva L3 12hr old  (15710) larva L3 puffstage 1-2  (15488) larva L3 puffstage 3-6  (16804) larva L3 puffstage 7-9  (19004) white prepupae new  (18480) white prepupae 12hr  (18080) white prepupae 24hr  (19650) pupae 2d postWPP  (15590) pupae 3d postWPP  (10283) pupae 4d postWPP  (10377) adult male 01day  (10272) adult male 05day  (11638) adult male 30day  (12163) adult female 01day  (24120) adult female 05day  (22835) adult female 30day  (23663) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (28149) embryo 02-04hr  (43769) embryo 04-06hr  (43015) embryo 06-08hr  (37078) embryo 08-10hr  (38491) embryo 10-12hr  (35468) embryo 12-14hr  (23385) embryo 14-16hr  (25646) embryo 16-18hr  (19740) embryo 18-20hr  (16882) embryo 20-22hr  (16618) embryo 22-24hr  (15787) larva L1  (28424) larva L2  (22736) larva L3 12hr old  (15710) larva L3 puffstage 1-2  (15488) larva L3 puffstage 3-6  (16804) larva L3 puffstage 7-9  (19004) white prepupae new  (18480) white prepupae 12hr  (18080) white prepupae 24hr  (19650) pupae 2d postWPP  (15590) pupae 3d postWPP  10283 pupae 4d postWPP  10377 adult male 01day  10272 adult male 05day  (11638) adult male 30day  (12163) adult female 01day  (24120) adult female 05day  (22835) adult female 30day  (23663) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28149 embryo 02-04hr    43769 embryo 04-06hr    43015 embryo 06-08hr    37078 embryo 08-10hr    38491 embryo 10-12hr    35468 embryo 12-14hr    23385 embryo 14-16hr    25646 embryo 16-18hr    19740 embryo 18-20hr    16882 embryo 20-22hr    16618 embryo 22-24hr    15787 larva L1    28424 larva L2    22736 larva L3 12hr old    15710 larva L3 puffstage 1-2    15488 larva L3 puffstage 3-6    16804 larva L3 puffstage 7-9    19004 white prepupae new    18480 white prepupae 12hr    18080 white prepupae 24hr    19650 pupae 2d postWPP    15590 pupae 3d postWPP    10283 pupae 4d postWPP    10377 adult male 01day    10272 adult male 05day    11638 adult male 30day    12163 adult female 01day    24120 adult female 05day    22835 adult female 30day    23663 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0015834 expression level Developmental Stage   Expression Level embryo 00-02hr    28149 embryo 02-04hr    43769 embryo 04-06hr    43015 embryo 06-08hr    37078 embryo 08-10hr    38491 embryo 10-12hr    35468 embryo 12-14hr    23385 embryo 14-16hr    25646 embryo 16-18hr    19740 embryo 18-20hr    16882 embryo 20-22hr    16618 embryo 22-24hr    15787 larva L1    28424 larva L2    22736 larva L3 12hr old    15710 larva L3 puffstage 1-2    15488 larva L3 puffstage 3-6    16804 larva L3 puffstage 7-9    19004 white prepupae new    18480 white prepupae 12hr    18080 white prepupae 24hr    19650 pupae 2d postWPP    15590 pupae 3d postWPP    10283 pupae 4d postWPP    10377 adult male 01day    10272 adult male 05day    11638 adult male 30day    12163 adult female 01day    24120 adult female 05day    22835 adult female 30day    23663 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (28149) embryo 02-04hr  (43769) embryo 04-06hr  (43015) embryo 06-08hr  (37078) embryo 08-10hr  (38491) embryo 10-12hr  (35468) embryo 12-14hr  (23385) embryo 14-16hr  (25646) embryo 16-18hr  (19740) embryo 18-20hr  (16882) embryo 20-22hr  (16618) embryo 22-24hr  (15787) larva L1  (28424) larva L2  (22736) larva L3 12hr old  (15710) larva L3 puffstage 1-2  (15488) larva L3 puffstage 3-6  (16804) larva L3 puffstage 7-9  (19004) white prepupae new  (18480) white prepupae 12hr  (18080) white prepupae 24hr  (19650) pupae 2d postWPP  (15590) pupae 3d postWPP  (10283) pupae 4d postWPP  (10377) adult male 01day  (10272) adult male 05day  (11638) adult male 30day  (12163) adult female 01day  (24120) adult female 05day  (22835) adult female 30day  (23663) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (28149) embryo 02-04hr  (43769) embryo 04-06hr  (43015) embryo 06-08hr  (37078) embryo 08-10hr  (38491) embryo 10-12hr  (35468) embryo 12-14hr  (23385) embryo 14-16hr  (25646) embryo 16-18hr  (19740) embryo 18-20hr  (16882) embryo 20-22hr  (16618) embryo 22-24hr  (15787) larva L1  (28424) larva L2  (22736) larva L3 12hr old  (15710) larva L3 puffstage 1-2  (15488) larva L3 puffstage 3-6  (16804) larva L3 puffstage 7-9  (19004) white prepupae new  (18480) white prepupae 12hr  (18080) white prepupae 24hr  (19650) pupae 2d postWPP  (15590) pupae 3d postWPP  (10283) pupae 4d postWPP  (10377) adult male 01day  (10272) adult male 05day  (11638) adult male 30day  (12163) adult female 01day  (24120) adult female 05day  (22835) adult female 30day  (23663) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (28149) embryo 02-04hr  (43769) embryo 04-06hr  (43015) embryo 06-08hr  (37078) embryo 08-10hr  (38491) embryo 10-12hr  (35468) embryo 12-14hr  (23385) embryo 14-16hr  (25646) embryo 16-18hr  19740 embryo 18-20hr  16882 embryo 20-22hr  16618 embryo 22-24hr  15787 larva L1  (28424) larva L2  (22736) larva L3 12hr old  15710 larva L3 puffstage 1-2  15488 larva L3 puffstage 3-6  16804 larva L3 puffstage 7-9  19004 white prepupae new  18480 white prepupae 12hr  18080 white prepupae 24hr  19650 pupae 2d postWPP  15590 pupae 3d postWPP  10283 pupae 4d postWPP  10377 adult male 01day  10272 adult male 05day  11638 adult male 30day  12163 adult female 01day  (24120) adult female 05day  (22835) adult female 30day  (23663) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28149 embryo 02-04hr    43769 embryo 04-06hr    43015 embryo 06-08hr    37078 embryo 08-10hr    38491 embryo 10-12hr    35468 embryo 12-14hr    23385 embryo 14-16hr    25646 embryo 16-18hr    19740 embryo 18-20hr    16882 embryo 20-22hr    16618 embryo 22-24hr    15787 larva L1    28424 larva L2    22736 larva L3 12hr old    15710 larva L3 puffstage 1-2    15488 larva L3 puffstage 3-6    16804 larva L3 puffstage 7-9    19004 white prepupae new    18480 white prepupae 12hr    18080 white prepupae 24hr    19650 pupae 2d postWPP    15590 pupae 3d postWPP    10283 pupae 4d postWPP    10377 adult male 01day    10272 adult male 05day    11638 adult male 30day    12163 adult female 01day    24120 adult female 05day    22835 adult female 30day    23663 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0015834    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0015834 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0015834 expression level Tissue   Expression Level Larval Central Nervous System    1535.975 Larval Midgut    1064.3 Larval Hindgut    1673.5 Larval Malpighian Tubules    1729.6 Larval Fat Body    1908.4 Larval Salivary Gland    3022.4 Larval Trachea    1900.325 Larval Carcass    1792.95 Adult Head    1286.1 Adult Eye    1580.15 Adult Brain    1262.9 Adult Thoracic-Abdominal Ganglion    1826.9 Adult Crop    1734.4 Adult Midgut    1395.1 Adult Hindgut    1588.1 Adult Malpighian Tubules    1324.8 Adult Fat Body    1586.5 Adult Salivary Gland    2425.8 Adult Heart    1407.875 Adult VirginFemale Spermatheca    1628.9 Adult InseminatedFemale Spermatheca    1527.5 Adult Ovary    1522.8 Adult Testis    400.7 Adult Male Accessory Gland    3292.1 Adult Carcass    1338.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1535.975) Larval Midgut  (1064.3) Larval Hindgut  (1673.5) Larval Malpighian Tubules  (1729.6) Larval Fat Body  (1908.4) Larval Salivary Gland  (3022.4) Larval Trachea  (1900.325) Larval Carcass  (1792.95) Adult Head  (1286.1) Adult Eye  (1580.15) Adult Brain  (1262.9) Adult Thoracic-Abdominal Ganglion  (1826.9) Adult Crop  (1734.4) Adult Midgut  (1395.1) Adult Hindgut  (1588.1) Adult Malpighian Tubules  (1324.8) Adult Fat Body  (1586.5) Adult Salivary Gland  (2425.8) Adult Heart  (1407.875) Adult VirginFemale Spermatheca  (1628.9) Adult InseminatedFemale Spermatheca  (1527.5) Adult Ovary  (1522.8) Adult Testis    400.7 Adult Male Accessory Gland  (3292.1) Adult Carcass  (1338.9) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1535.975) Larval Midgut  1064.3 Larval Hindgut  (1673.5) Larval Malpighian Tubules  (1729.6) Larval Fat Body  (1908.4) Larval Salivary Gland  (3022.4) Larval Trachea  (1900.325) Larval Carcass  (1792.95) Adult Head  (1286.1) Adult Eye  (1580.15) Adult Brain  (1262.9) Adult Thoracic-Abdominal Ganglion  (1826.9) Adult Crop  (1734.4) Adult Midgut  (1395.1) Adult Hindgut  (1588.1) Adult Malpighian Tubules  (1324.8) Adult Fat Body  (1586.5) Adult Salivary Gland  (2425.8) Adult Heart  (1407.875) Adult VirginFemale Spermatheca  (1628.9) Adult InseminatedFemale Spermatheca  (1527.5) Adult Ovary  (1522.8) Adult Testis    400.7 Adult Male Accessory Gland  (3292.1) Adult Carcass  (1338.9) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1535.975 Larval Midgut    1064.3 Larval Hindgut    1673.5 Larval Malpighian Tubules    1729.6 Larval Fat Body    1908.4 Larval Salivary Gland    3022.4 Larval Trachea    1900.325 Larval Carcass    1792.95 Adult Head    1286.1 Adult Eye    1580.15 Adult Brain    1262.9 Adult Thoracic-Abdominal Ganglion    1826.9 Adult Crop    1734.4 Adult Midgut    1395.1 Adult Hindgut    1588.1 Adult Malpighian Tubules    1324.8 Adult Fat Body    1586.5 Adult Salivary Gland    2425.8 Adult Heart    1407.875 Adult VirginFemale Spermatheca    1628.9 Adult InseminatedFemale Spermatheca    1527.5 Adult Ovary    1522.8 Adult Testis    400.7 Adult Male Accessory Gland    3292.1 Adult Carcass    1338.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0015834 expression level Tissue   Expression Level Larval Central Nervous System    1535.975 Larval Midgut    1064.3 Larval Hindgut    1673.5 Larval Malpighian Tubules    1729.6 Larval Fat Body    1908.4 Larval Salivary Gland    3022.4 Larval Trachea    1900.325 Larval Carcass    1792.95 Adult Head    1286.1 Adult Eye    1580.15 Adult Brain    1262.9 Adult Thoracic-Abdominal Ganglion    1826.9 Adult Crop    1734.4 Adult Midgut    1395.1 Adult Hindgut    1588.1 Adult Malpighian Tubules    1324.8 Adult Fat Body    1586.5 Adult Salivary Gland    2425.8 Adult Heart    1407.875 Adult VirginFemale Spermatheca    1628.9 Adult InseminatedFemale Spermatheca    1527.5 Adult Ovary    1522.8 Adult Testis    400.7 Adult Male Accessory Gland    3292.1 Adult Carcass    1338.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1535.975) Larval Midgut  (1064.3) Larval Hindgut  (1673.5) Larval Malpighian Tubules  (1729.6) Larval Fat Body  (1908.4) Larval Salivary Gland  (3022.4) Larval Trachea  (1900.325) Larval Carcass  (1792.95) Adult Head  (1286.1) Adult Eye  (1580.15) Adult Brain  (1262.9) Adult Thoracic-Abdominal Ganglion  (1826.9) Adult Crop  (1734.4) Adult Midgut  (1395.1) Adult Hindgut  (1588.1) Adult Malpighian Tubules  (1324.8) Adult Fat Body  (1586.5) Adult Salivary Gland  (2425.8) Adult Heart  (1407.875) Adult VirginFemale Spermatheca  (1628.9) Adult InseminatedFemale Spermatheca  (1527.5) Adult Ovary  (1522.8) Adult Testis    400.7 Adult Male Accessory Gland  (3292.1) Adult Carcass  (1338.9) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1535.975 Larval Midgut  1064.3 Larval Hindgut  1673.5 Larval Malpighian Tubules  (1729.6) Larval Fat Body  (1908.4) Larval Salivary Gland  (3022.4) Larval Trachea  (1900.325) Larval Carcass  (1792.95) Adult Head  1286.1 Adult Eye  1580.15 Adult Brain  1262.9 Adult Thoracic-Abdominal Ganglion  (1826.9) Adult Crop  (1734.4) Adult Midgut  1395.1 Adult Hindgut  1588.1 Adult Malpighian Tubules  1324.8 Adult Fat Body  1586.5 Adult Salivary Gland  (2425.8) Adult Heart  1407.875 Adult VirginFemale Spermatheca  1628.9 Adult InseminatedFemale Spermatheca  1527.5 Adult Ovary  1522.8 Adult Testis    400.7 Adult Male Accessory Gland  (3292.1) Adult Carcass  1338.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1535.975 Larval Midgut    1064.3 Larval Hindgut    1673.5 Larval Malpighian Tubules    1729.6 Larval Fat Body    1908.4 Larval Salivary Gland    3022.4 Larval Trachea    1900.325 Larval Carcass    1792.95 Adult Head    1286.1 Adult Eye    1580.15 Adult Brain    1262.9 Adult Thoracic-Abdominal Ganglion    1826.9 Adult Crop    1734.4 Adult Midgut    1395.1 Adult Hindgut    1588.1 Adult Malpighian Tubules    1324.8 Adult Fat Body    1586.5 Adult Salivary Gland    2425.8 Adult Heart    1407.875 Adult VirginFemale Spermatheca    1628.9 Adult InseminatedFemale Spermatheca    1527.5 Adult Ovary    1522.8 Adult Testis    400.7 Adult Male Accessory Gland    3292.1 Adult Carcass    1338.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1286.1   NA  Eye    1580.15   NA  Brain    1262.9   1535.975  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1826.9   NA  Crop    1734.4   1064.3  Midgut    1395.1   1673.5  Hindgut    1588.1   1729.6  Malpighian Tubules    1324.8   1908.4  Fat Body    1586.5   3022.4  Salivary Gland    2425.8   NA  Heart    1407.875   1900.325  Trachea    NA   NA  VirginFemale Spermatheca    1628.9   NA  InseminatedFemale Spermatheca    1527.5   NA  Ovary    1522.8   NA  Testis    400.7   NA  Male Accessory Gland    3292.1   1792.95  Carcass    1338.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015834 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8882-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 Trip1GD14057 lethal | pupal stage, with Scer\GAL4pnr-MD237 Trip1GD14057 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Trip1 Class Mutagen Stocks Known lesion Trip1KG06360 P-element activity 2 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Trip1 Class Mutagen Stocks Known lesion Trip1GD14057 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Trip1HMS01387 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Trip1KK107698 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7021 (Ryder, 2004.4.26) Df(2L)Exel8012 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14057} NA P{KK107698} NA P{TRiP.HMS01387} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}Trip1KG06360 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
microtubule associated complex inferred from direct assay (Hughes et al., 2008)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
translation initiation factor activity inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with Saccharomyces TIF34 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1998.2.1)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with Saccharomyces TIF34 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1998.2.1) translational initiation inferred from sequence or structural similarity (Lasko, 2000)
Cellular Component
CV term Evidence References
cytosol non-traceable author statement (Swiss-Prot Project Members, 1998.2.1) eukaryotic translation initiation factor 3 complex inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with Saccharomyces TIF34 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1998.2.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Trip1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59895 DroID - A comprehensive database of gene and protein interactions. • FBgn0015834 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33710
Orthologs
Genome-wide drosophilid orthologs	Dana\GF23646 Dere\GG24335 Dgri\GH10244 Dmoj\GI15375 Dper\GL26537 Dpse\GA21387 Dsec\GM18055 Dsim\GD22675 Dvir\GJ17275 Dwil\GK24461 Dyak\Trip1
Curated drosophilid orthologs	Dpse\GA21387   Dyak\Trip1
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013144-PA Aedes aegypti (mosquito) AGAP006607-PA Anopheles gambiae (mosquito) XP_392780.2 Apis mellifera (honey bee) XP_001951798.1 Acyrthosiphon pisum (pea aphid) At2g46290.1 Arabidopsis thaliana (wall cress) 84729 Batrachochytrium dendrobatidis (chytrid fungus) BGIBMGA007889-PA Bombyx mori (silk worm) ENSBTAP00000019134 Bos taurus (bovine) CAL0006083 Candida albicans (a form of yeast) CBP06619 Caenorhabditis briggsae (nematode) CE30325 Caenorhabditis elegans (worm) ENSCAFP00000015742 Canis familiaris (dog) CAGL0L06952g Candida glabrata (haploid yeast) Chro.50323 Cryptosporidium hominis (obligate parasite) ENSCINP00000026754 Ciona intestinalis (sea squirt) JA16162 Caenorhabditis japonica (nematode) CMC064C Cyanidioschyzon merolae (red alga) cn01574 Cryptococcus neoformans (yeast-like fungus) cgd5_680 Cryptosporidium parvum (protozoan parasite) CPIJ018275 Culex pipens (mosquito) CPIJ018457 Culex pipens (mosquito) ENSCPOP00000010790 Cavia porcellus (guinea pig) 79571 Chlamidomonas reinhardtii (green alga) RP33553 Caenorhabditis remanei (nematode) 180537 Capitella spl (polychaete worm) DDB0233910 Dictyostelium discoideum (amoeba) DEHA2D07898g Debaryomyces Hansenii (yeast) 304176 Daphnia pulex (daphnia) ENSDARP00000017792 Danio rerio (zebra fish) ENSECAP00000011571 Equus caballus (horse) XP_654125 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000012059 Gymnopilus aculeatus (mushroom) ENSGALP00000005271 Gallus gallus (chicken) GL50803_13661 Giardia lamblia (flagellated protozoan) 185422 Hypsipyla robusta (cedar shoot borer) ENSP00000362688 Homo sapiens (human) ISCW000011-PA Ixodes scapularis (deer tick) KLLA0F07403g Kluyveromyces lactis (yeast) 200332 Lottia gigantea (owl limpet) LmjF36.3880 Leishmania major (virus) 13028 Monocosta brevicollis (choanoflagellate) ENSMODP00000021812 Monodelphis domestica (gray opossum) ENSMMUP00000008043 Macaca mulatta (rhesus monkey) ENSMUSP00000099653 Mus musculus (house mouse) 239264 Nematostella vectensis (starlet anemone) XP_001603140.1 Nasonia vitripennis (wasp) ENSOANP00000001912 Ornithorynchus anatinus (platypus) ENSORLP00000017731 Oryzias latipes (japanese killifish) LOC_Os05g16660.1 Oryza sativa (asian rice) LOC_Os08g21660.1 Oryza sativa (asian rice) 8481 Ostreococcus tauri (green alga) MAL7P1.81 Plasmodium falciparum (protozoal parasite) PHUM004126-PA Pediculus humanus (human body louse) PP09717 Pristionchus pacificus (nematode) 161649 Physcomitrella patens (moss) ENSPPYP00000001842 Pongo pygmaeus (orangutan) 72142 Phytophthora ramorum (sudden oak death pathogen) 109545 Phytophthora sojae (root rot pathogen) 720028 Populus trichocarpa (black cottonwood) 833555 Populus trichocarpa (black cottonwood) ENSPTRP00000000837 Pan troglodytes (chimpanzee) PVX_000590 Plasmodium vivax (protozoal parasite) ENSRNOP00000037347 Rattus norvegicus (norway rat) 4873317 Sorghum bicolor (sorghum) YMR146C Saccharomyces cerevisiae (budding yeast) Smp_006000 Schistosoma mansoni (trematode parasite) SPAC4D7.05 Schizosaccharomyces pombe (fission yeast) 50764 Trichoplax adhaerens (metazoa) TA16275 Theileria annulata (apicomplexan parasite) XP_967415.1 Tribolium castaneum (red flour beetle) Tc00.1047053511229.80 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511589.230 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000012137 Tetraodon nigroviridis (green spotted pufferfish) TP01_1092 Theileria parva (parasitic protozoan) 26686 Thalassiosira pseudonana (marine diatom) ENSTRUP00000026583 Takifugu rubripes (pufferfish Takifugu) 16.m00367 Tetrahymena thermophila (ciliate protozoa) 84109.m00059 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000011458 Xenopus tropicalis (frog) YALI0A02695g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11130 NV16857 LH22202 ISCW000011 FBgn0068012 FBgn0226421 FBgn0204451 FBgn0194072 FBgn0172962 JGI_V11_304176 FBgn0081375 FBgn0164119 FBgn0138124 FBgn0117725 FBgn0116467 FBgn0100640 CPIJ018457 CPIJ018275 BGIBMGA007889 ACYPI007923 ACYPI003750 ACYPI000798 GB13416 EIF3I_ANOGA AAEL015547 AAEL013144 PHUM561140 GLEAN_02391
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	34978 y1 sc* v1; P{TRiP.HMS01387}attP2 14294 y1; P{SUPor-P}Trip1KG06360/CyO; ry506
Kyoto	114383 yd2 w1118 P{ey-FLP.N}2; P{SUPor-P}Trip1KG06360 P{neoFRT}40A/CyO y+
VDRC	v103141 P{KK107698}VIE-260B v28976 w1118; P{GD14057}v28976
Genomic Clones ( 2 )
	BACR13M11 BACR40I04 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 297 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD24026
Other clones	yak-ad_Trip1
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05458 AT14303 AT19691 GH04894 GH11348 GH14053 GH14342 GH18335 GH18476 GH24962 GH26105 GM01027 GM01509 GM02261 GM04005 GM04041 GM04508 GM10229 GM10314 GM15395 GM21995 GM31441 LD06066 LD06439 LD07746 LD10696 LD15739 LD16803 LD20827 LD21691 LD23265 LD23912 LD24423 LD25195 LD27235 LD32815 LD32886 LD34481 LD34921 LD36632 LD40665 LD41091 LD42564 LD42837 LD43470 LD46321 LD47360 LD47716 LP03724 LP05558 LP10220 LP15411 LP22447 RE30567 RE39027 RE47203 RE47521 RE62276 RE66639 RE68360 RE68368 RE69252 RE71484 RE71894 RE73212 RH03819 RH06903 RH10430 RH10624 RH12345 RH12747 RH14258 RH20616 RH22047 RH23145 RH24009 RH25713 RH26606 RH27368 RH28286 RH28566 RH33490 RH36474 RH36659 RH39554 RH41505 RH41762 RH46512 RH46701 RH47563 RH49760 RH50136 RH51047 RH51081 RH51669 RH52557 RH53733 RH53943 RH54273 RH55114 RH56350 RH58193 RH58887 RH60776 RH60914 RH61967 RH62696 RH70616 RH71122 RH72443 RH73022 RH74208 RH74421 RH74706 SD16186 SD16325 SD16544 SD17479 SD21363 SD22680 SD23962 SD25495 SD27887
Other clones	bs68h12 Dmel_dig_009612_0709_3246 Dmel_dig_013433_0707_3187 Dmel_dig_014981_0712_2003 Dmel_neb_013973_0169_0462 EC01893 EK056012 EK129363 EK169210 EK172527 EK197959 EK248927 EN05006 EN07107 EN08005 EN11004 EN13858 FGA009F06 FGC027D06 FGH103H10 FGM102C09 FGM102G07 FGM103D06 FGM237F09 GH04085 IP17618 IP17918 LD14130 LD20546 LD24276 RE08145 RE12494 RE15051 RE22921 RE23183 RE24139 RE27266 RE33692 RE36849 RE45296 RE52674 RE57245 RE63073 RE63152 RE66629 RE67884 RE68067 RE68317 RE68869 RE71768 RE72491 RE74441 RH01043 RH09570 RH09765 RH10088 RH12859 RH14570 RH15917 RH16251 RH25393 RH28089 RH28793 RH35547 RH39968 RH47028 RH56792 RH58645 RH60449 RH66363 RH70534 RP003010909 RP003015471 RP003023097 RP003026162 RP003026825 RP003032358 RP003036586 RP003044559 RP003049333 RP003049950 RP003061164 RP003062127 RP003083566 RP003085047 RP003087341 RP003103282 RP003111253 RP003117410 RP003119057 RP003122701 RP003128586 RP003129302 RP003130809 RP003139535 RP003143977 RP003152199 RP003153483 RP003160170 RP003166875 RP003170221 RP003172286 RP003176464 RP003184448 RP003185622 RP003196290 RP003198180 RP003198550 RP003206844 RP003214886 RP003218906 RP003219520 RP003220448 RP003245441 RP003248668 RP003251076 RP003254711 RP003260033 RP003260116 RP003263700 RP003279463 RP003284214 RP003285924 RP003286855 RP003303832 RP003311337 RP003312674 RP003322692 RP003325722 RP003326205 RP003334340 RP003335194 RP003336166 RP003340144 RP003351916 RP003356427 RP003358503 RP003359363 RP003364397 RP003370248 RP003386595 RP003400111 RP003419634 RP003427054 RP003433582 RP003444154 RP003452384 RP003455451 RP003462710 RP003470485 RP003484551 RP003487253 RP003489443 RP003489546 RP003489611 RP003492200 RP003510892 RP003519029 RP003544364 RP003548376 RP003573334 RP003575346 RP003575661 RP003589348 RP003628224 RP003632901 RP003641199 RP003643274 RP003653249 RP003668114 UT01455 UUGC0847
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0015834 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33710
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Trip1 CG8882 (Kodira, 1999.11)
Source for database merge of
Additional comments
Other Comments
	Cloned by PCR as being similar to Hsap\TRIP-1. (Cho et al., 1996)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078754 RefSeq (Proteins) • NP_523478 DDBJ / EMBL / GenBank • AA820418 AAB53431 AAF52183 AAF52183.1 AAM49896 AW942693 AY118527 BH840669 U90930 Entrez Gene - A searchable database of RefSeq genes. • 33710 UniProtKB/Swiss-Prot • O02195
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • WD40/YVTN repeat-like-containing domain (IPR015943) WD40-repeat-containing domain (IPR017986) WD40 repeat (IPR001680) WD40 repeat-like-containing domain (IPR011046) WD40 repeat, conserved site (IPR019775) WD40 repeat, subgroup (IPR019781) WD40 repeat 2 (IPR019782)
Linkouts
	BioGRID - A database of protein and genetic interactions • 59895 DroID - A comprehensive database of gene and protein interactions. • FBgn0015834 DRSC - Results from RNAi screens. • FBgn0015834 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015834 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8882-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0015834 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33710 InParanoid A subset of ortholog calls from InParanoid. • AAEL013144-PA Aedes aegypti (mosquito) AGAP006607-PA Anopheles gambiae (mosquito) XP_392780.2 Apis mellifera (honey bee) XP_001951798.1 Acyrthosiphon pisum (pea aphid) At2g46290.1 Arabidopsis thaliana (wall cress) 84729 Batrachochytrium dendrobatidis (chytrid fungus) BGIBMGA007889-PA Bombyx mori (silk worm) ENSBTAP00000019134 Bos taurus (bovine) CAL0006083 Candida albicans (a form of yeast) CBP06619 Caenorhabditis briggsae (nematode) CE30325 Caenorhabditis elegans (worm) ENSCAFP00000015742 Canis familiaris (dog) CAGL0L06952g Candida glabrata (haploid yeast) Chro.50323 Cryptosporidium hominis (obligate parasite) ENSCINP00000026754 Ciona intestinalis (sea squirt) JA16162 Caenorhabditis japonica (nematode) CMC064C Cyanidioschyzon merolae (red alga) cn01574 Cryptococcus neoformans (yeast-like fungus) cgd5_680 Cryptosporidium parvum (protozoan parasite) CPIJ018275 Culex pipens (mosquito) CPIJ018457 Culex pipens (mosquito) ENSCPOP00000010790 Cavia porcellus (guinea pig) 79571 Chlamidomonas reinhardtii (green alga) RP33553 Caenorhabditis remanei (nematode) 180537 Capitella spl (polychaete worm) DDB0233910 Dictyostelium discoideum (amoeba) DEHA2D07898g Debaryomyces Hansenii (yeast) 304176 Daphnia pulex (daphnia) ENSDARP00000017792 Danio rerio (zebra fish) ENSECAP00000011571 Equus caballus (horse) XP_654125 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000012059 Gymnopilus aculeatus (mushroom) ENSGALP00000005271 Gallus gallus (chicken) GL50803_13661 Giardia lamblia (flagellated protozoan) 185422 Hypsipyla robusta (cedar shoot borer) ENSP00000362688 Homo sapiens (human) ISCW000011-PA Ixodes scapularis (deer tick) KLLA0F07403g Kluyveromyces lactis (yeast) 200332 Lottia gigantea (owl limpet) LmjF36.3880 Leishmania major (virus) 13028 Monocosta brevicollis (choanoflagellate) ENSMODP00000021812 Monodelphis domestica (gray opossum) ENSMMUP00000008043 Macaca mulatta (rhesus monkey) ENSMUSP00000099653 Mus musculus (house mouse) 239264 Nematostella vectensis (starlet anemone) XP_001603140.1 Nasonia vitripennis (wasp) ENSOANP00000001912 Ornithorynchus anatinus (platypus) ENSORLP00000017731 Oryzias latipes (japanese killifish) LOC_Os05g16660.1 Oryza sativa (asian rice) LOC_Os08g21660.1 Oryza sativa (asian rice) 8481 Ostreococcus tauri (green alga) MAL7P1.81 Plasmodium falciparum (protozoal parasite) PHUM004126-PA Pediculus humanus (human body louse) PP09717 Pristionchus pacificus (nematode) 161649 Physcomitrella patens (moss) ENSPPYP00000001842 Pongo pygmaeus (orangutan) 72142 Phytophthora ramorum (sudden oak death pathogen) 109545 Phytophthora sojae (root rot pathogen) 720028 Populus trichocarpa (black cottonwood) 833555 Populus trichocarpa (black cottonwood) ENSPTRP00000000837 Pan troglodytes (chimpanzee) PVX_000590 Plasmodium vivax (protozoal parasite) ENSRNOP00000037347 Rattus norvegicus (norway rat) 4873317 Sorghum bicolor (sorghum) YMR146C Saccharomyces cerevisiae (budding yeast) Smp_006000 Schistosoma mansoni (trematode parasite) SPAC4D7.05 Schizosaccharomyces pombe (fission yeast) 50764 Trichoplax adhaerens (metazoa) TA16275 Theileria annulata (apicomplexan parasite) XP_967415.1 Tribolium castaneum (red flour beetle) Tc00.1047053511229.80 Trypanosoma cruzi (parasitic trypanosome) Tc00.1047053511589.230 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000012137 Tetraodon nigroviridis (green spotted pufferfish) TP01_1092 Theileria parva (parasitic protozoan) 26686 Thalassiosira pseudonana (marine diatom) ENSTRUP00000026583 Takifugu rubripes (pufferfish Takifugu) 16.m00367 Tetrahymena thermophila (ciliate protozoa) 84109.m00059 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000011458 Xenopus tropicalis (frog) YALI0A02695g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33710 modMine - Data generated by the modENCODE project. • FBgn0015834 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB11130 NV16857 LH22202 ISCW000011 FBgn0068012 FBgn0226421 FBgn0204451 FBgn0194072 FBgn0172962 JGI_V11_304176 FBgn0081375 FBgn0164119 FBgn0138124 FBgn0117725 FBgn0116467 FBgn0100640 CPIJ018457 CPIJ018275 BGIBMGA007889 ACYPI007923 ACYPI003750 ACYPI000798 GB13416 EIF3I_ANOGA AAEL015547 AAEL013144 PHUM561140 GLEAN_02391
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG8882 (Lasko, 2000, Pisa et al., 2009, Keleman et al., 2009.8.5, Hughes et al., 2008, Ni et al., 2011.7.19, Cammarato et al., 2011) DmTRIP (Cho, 1997.2.26, ) eIF3-S2 (Lasko, 2000, Andersen and Leevers, 2007, Somma et al., 2008) eIF-3β (Pisa et al., 2009) Trip1 (Stuart et al., 2007, Somma et al., 2008, Pisa et al., 2009, Mourikis et al., 2010, Dekanty et al., 2010)
Name Synonym	Trip1 (Cho et al., 1996, Somma et al., 2008, Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 28 )
Generate a list of	All references relating to this gene ( 28 )
List References by type	Research paper  ( 10 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 4 ) Abstract  ( 1 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 ) Protein sequence record  ( 1 ) Computer file  ( 2 ) Automatic genome annotation  ( 1 )
Recent research papers ( 3 )
	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Dekanty et al., 2010, PLoS Genet. 6(6): e1000994 Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF-Dependent Transcription in Hypoxia. [FBrf0211155] Mourikis et al., 2010, BMC Dev. Biol. 10: 107 Modifiers of notch transcriptional activity identified by genome-wide RNAi. [FBrf0212287] Show all research papers ...