FB2025_02 , released April 17, 2025
Gene: Dmel\Sema1b
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General Information
Symbol
Dmel\Sema1b
Species
D. melanogaster
Name
Semaphorin 1b
Annotation Symbol
CG6446
Feature Type
protein_coding_gene
FlyBase ID
FBgn0016059
Gene Model Status
Current
Stock Availability
11 publicly available
Gene Summary
Contribute a Gene Snapshot for this gene.
All Summaries
Also Known As

Sema-1b, semaphorin, sema-III, semaphorin-like, Sema 1b

Key Links
Genomic Location
Cytogenetic map
54D4-54D5
Sequence location
Recombination map
2-83
RefSeq locus
NT_033778 REGION:17672839..17683499
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (9 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables chemorepellent activity
inferred from biological aspect of ancestor with PANTHER:PTN000867340
(GO Reference Genome Project, 2011-)
enables semaphorin receptor binding
inferred from electronic annotation with InterPro:IPR027231, InterPro:IPR042068
(InterPro Project Members, 2004-)
inferred from biological aspect of ancestor with PANTHER:PTN000112368
(GO Reference Genome Project, 2011-)
Biological Process (5 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
involved_in embryonic development via the syncytial blastoderm
inferred from expression pattern
(Khare et al., 2000)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
involved_in axon guidance
inferred from biological aspect of ancestor with PANTHER:PTN000112368
(GO Reference Genome Project, 2011-)
involved_in negative chemotaxis
inferred from biological aspect of ancestor with PANTHER:PTN000744245
(GO Reference Genome Project, 2011-)
involved_in positive regulation of cell migration
inferred from biological aspect of ancestor with PANTHER:PTN000867340
(GO Reference Genome Project, 2011-)
involved_in semaphorin-plexin signaling pathway
inferred from biological aspect of ancestor with PANTHER:PTN000112368
(GO Reference Genome Project, 2011-)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in cytosol
inferred from high throughput direct assay
(Lye et al., 2014)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in plasma membrane
inferred from biological aspect of ancestor with PANTHER:PTN000867340
(GO Reference Genome Project, 2011-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
SEMAPHORINS -
The Semaphorins are a family of membrane and secreted short-range signaling proteins, originally characterized for their role in axon guidance. The major signal transducing receptors for the semaphorins are the plexins. (Adapted from FBrf0233112, FBrf0137217 and PMID:23253452).
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Sema1b for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q7KK54)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
PDB - An information portal to biological macromolecular structures
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.50

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Sema1b-RA
FBtr0086890
NM_137400
4269
770
Sema1b-RB
FBtr0086891
NM_206157
4262
770
Sema1b-RC
FBtr0302161
NM_001169707
3910
770
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Sema1b-PA
FBpp0086050
85.2
770
6.96
Q7KK54
NP_611244
AAF57816
Sema1b-PB
FBpp0089289
85.2
770
6.96
Q7KK54
NP_995879
AAS64817
Sema1b-PC
FBpp0291371
85.2
770
6.96
Q7KK54
NP_001163178
ACZ94450
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

770 aa isoforms: Sema1b-PA, Sema1b-PB, Sema1b-PC
Additional Polypeptide Data and Comments
Reported size (kDa)

759 (aa); 84 (kD predicted)

(Khare et al., 2000)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
PDB - An information portal to biological macromolecular structures
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sema1b using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.56

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 5 -- 6
mesectoderm
(Kearney et al., 2004)
embryonic stage 5 -- 7
ventral ectoderm

Comment: bilateral stripes, 1-2 cells wide

(Khare et al., 2000)
embryonic stage 7 -- 8
mesectoderm anlage
(Kearney et al., 2004)
embryonic stage 8 -- 10
ventral midline of embryo
(Khare et al., 2000)
embryonic stage 9 -- 12
midline primordium
(Kearney et al., 2004)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage & pupal stage
(Khare et al., 2000)
embryonic stage 2
organism | ubiquitous
(Khare et al., 2000)
embryonic stage 5 -- 10
mesectoderm
(Khare et al., 2000)
embryonic stage 12 -- 15
ectoderm
(Khare et al., 2000)
adult stageoogenesis stage S2 -- S8
ovariole
(Khare et al., 2000)
adult stage & oogenesis stage S10
nurse cell
(Khare et al., 2000)
Additional Descriptive Data

Sema1b transcripts are first expressed in early stages of oogenesis where staining is observed in ovarioles and nurse cells. In early embryos, staining is uniform. At stage 5, Sema1b transcripts are observed in two lateral stripes of 1-2 cells wide. These stripes meet at the ventral surface at stage 8 as a result of ventral furrow formation and may be mesectodermal cells. In later embryonic stages, staining is primarily in the ectoderm.

(Khare et al., 2000)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in cytosol
inferred from high throughput direct assay
(Lye et al., 2014)
Expression Deduced from Reporters
Reporter: P{GawB}Sema1bNP1166
Stage
Tissue/Position (including subcellular localization)
Reference
oogenesis
polar follicle cell
(Wittes and Schüpbach, 2019)
follicle cell

Comment: posterior follicle cell

(Wittes and Schüpbach, 2019)
Reporter: PBac{806.LOX-SVS-2}Sema1bCPTI003971
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
lamina
(Knowles-Barley, 2011.8.24)
adult brain cell body rind
(Knowles-Barley, 2011.8.24)
oogenesis
polar follicle cell
(Wittes and Schüpbach, 2019)
follicle cell

Comment: posterior follicle cell

(Wittes and Schüpbach, 2019)
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Sema1b in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 9 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Sema1b
Transgenic constructs containing regulatory region of Sema1b
Aberrations (Deficiencies and Duplications) ( 1 )
Inferred from experimentation ( 1 )
Gene disrupted in
Df(2R)Exel7149
(Ryder, 2004.4.26)
Inferred from location ( 5 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (30)
Hsap\SEMA6A
9 of 14
Yes
Yes
Hsap\SEMA6B
9 of 14
Yes
Yes
Hsap\SEMA6D
9 of 14
Yes
Yes
Hsap\SEMA6C
8 of 14
No
Yes
Hsap\SEMA3A
4 of 14
No
No
Hsap\SEMA3B
4 of 14
No
No
Hsap\SEMA3C
4 of 14
No
Yes
Hsap\SEMA3D
4 of 14
No
No
Hsap\SEMA3F
4 of 14
No
No
Hsap\SEMA3G
4 of 14
No
Yes
Hsap\SEMA3E
3 of 14
No
Yes
Hsap\SEMA4A
3 of 14
No
Yes
1  
Hsap\SEMA4B
3 of 14
No
Yes
Hsap\SEMA4C
3 of 14
No
Yes
Hsap\SEMA4D
3 of 14
No
Yes
Hsap\SEMA4F
3 of 14
No
Yes
Hsap\SEMA4G
3 of 14
No
Yes
Hsap\SEMA7A
3 of 14
No
Yes
Hsap\SEMA5A
2 of 14
No
No
Hsap\SEMA5B
2 of 14
No
No
Hsap\ADAMTS9
1 of 14
No
No
Hsap\HMCN1
1 of 14
No
No
Hsap\PLXNA1
1 of 14
No
No
Hsap\PLXNA2
1 of 14
No
No
Hsap\PLXNA3
1 of 14
No
No
1  
Hsap\PLXNA4
1 of 14
No
No
1  
Hsap\PLXNB1
1 of 14
No
No
Hsap\PLXNB2
1 of 14
No
No
1  
Hsap\PLXNB3
1 of 14
No
No
1  
Hsap\SSPOP
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (20)
Rnor\Sema6b
9 of 14
Yes
Yes
Rnor\Sema6d
9 of 14
Yes
Yes
Rnor\Sema6a
8 of 14
No
Yes
Rnor\Sema6c
8 of 14
No
Yes
Rnor\Sema3a
4 of 14
No
No
Rnor\Sema3b
4 of 14
No
No
Rnor\Sema3c
4 of 14
No
No
Rnor\Sema3d
4 of 14
No
No
Rnor\Sema3e
4 of 14
No
No
Rnor\Sema3f
4 of 14
No
No
Rnor\Sema3g
4 of 14
No
No
Rnor\Sema4a
3 of 14
No
Yes
Rnor\Sema4c
3 of 14
No
No
Rnor\Sema4d
3 of 14
No
No
Rnor\Sema4f
3 of 14
No
Yes
Rnor\Sema4g
3 of 14
No
No
Rnor\Sema4b
2 of 14
No
No
Rnor\Sema5a
2 of 14
No
No
Rnor\Sema5b
2 of 14
No
No
Rnor\Sema7a
2 of 14
No
Yes
Mus musculus (laboratory mouse) (21)
Mmus\Sema6a
9 of 14
Yes
Yes
Mmus\Sema6b
9 of 14
Yes
Yes
Mmus\Sema6d
9 of 14
Yes
Yes
Mmus\Sema6c
8 of 14
No
Yes
Mmus\Sema3a
4 of 14
No
No
Mmus\Sema3b
4 of 14
No
No
Mmus\Sema3c
4 of 14
No
Yes
Mmus\Sema3d
4 of 14
No
No
Mmus\Sema3e
4 of 14
No
Yes
Mmus\Sema3f
4 of 14
No
No
Mmus\Sema3g
4 of 14
No
Yes
Mmus\Sema4a
3 of 14
No
Yes
Mmus\Sema4b
3 of 14
No
Yes
Mmus\Sema4c
3 of 14
No
Yes
Mmus\Sema4d
3 of 14
No
Yes
Mmus\Sema4f
3 of 14
No
Yes
Mmus\Sema4g
3 of 14
No
Yes
Mmus\Sema5a
2 of 14
No
No
Mmus\Sema5b
2 of 14
No
No
Mmus\Sema7a
2 of 14
No
Yes
Mmus\Sspo
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (22)
Xtro\sema6b
7 of 13
Yes
Yes
Xtro\sema6c
6 of 13
No
Yes
Xtro\sema6d
6 of 13
No
Yes
Xtro\dvl3
4 of 13
No
No
Xtro\sema6a
4 of 13
No
Yes
Xtro\sema3b
3 of 13
No
No
Xtro\dok2
2 of 13
No
No
Xtro\sema4c
2 of 13
No
Yes
Xtro\sema4d
2 of 13
No
Yes
Xtro\sema4g
2 of 13
No
No
Xtro\hmcn1
1 of 13
No
No
Xtro\krt80
1 of 13
No
Yes
Xtro\plxna2
1 of 13
No
No
Xtro\plxnb2
1 of 13
No
No
Xtro\plxnb3
1 of 13
No
No
Xtro\sdf2l1
1 of 13
No
No
Xtro\sema3a
1 of 13
No
No
Xtro\sema3c
1 of 13
No
Yes
Xtro\sema3d
1 of 13
No
No
Xtro\sema4a
1 of 13
No
Yes
Xtro\sema4b
1 of 13
No
No
Xtro\sema5b
1 of 13
No
No
Danio rerio (Zebrafish) (35)
Drer\sema6e
9 of 14
Yes
Yes
Drer\sema6ba
8 of 14
No
Yes
Drer\sema6bb
8 of 14
No
Yes
Drer\sema6d
8 of 14
No
Yes
Drer\sema6dl
8 of 14
No
Yes
Drer\sema3aa
4 of 14
No
No
Drer\sema3ab
4 of 14
No
No
Drer\sema3b
4 of 14
No
No
Drer\sema3bl
4 of 14
No
No
Drer\sema3e
4 of 14
No
No
Drer\sema3fa
4 of 14
No
No
Drer\sema3fb
4 of 14
No
No
Drer\sema3ga
4 of 14
No
No
Drer\sema3gb
4 of 14
No
No
Drer\sema3h
4 of 14
No
No
Drer\sema3c
3 of 14
No
Yes
Drer\sema3d
3 of 14
No
No
Drer\sema4ab
3 of 14
No
Yes
Drer\sema4bb
3 of 14
No
Yes
Drer\sema4c
3 of 14
No
Yes
Drer\sema4e
3 of 14
No
No
Drer\sema4ga
3 of 14
No
Yes
Drer\sema4gb
3 of 14
No
Yes
Drer\sema6a
3 of 14
No
Yes
Drer\si:dkey-49n23.1
3 of 14
No
No
Drer\LOC798168
2 of 14
No
Yes
Drer\sema4ba
2 of 14
No
Yes
Drer\sema4f
2 of 14
No
Yes
Drer\sema5ba
2 of 14
No
No
Drer\sema5bb
2 of 14
No
No
Drer\sema7a
2 of 14
No
Yes
Drer\si:ch211-129c21.1
2 of 14
No
No
Drer\LOC100537452
1 of 14
No
Yes
Drer\sema5a
1 of 14
No
No
Drer\si:ch211-113g11.6
1 of 14
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (8)
Cele\smp-1
9 of 14
Yes
No
Cele\smp-2
3 of 14
No
Yes
Cele\mab-20
2 of 14
No
No
Cele\adt-1
1 of 14
No
No
Cele\adt-2
1 of 14
No
No
Cele\C36B7.5
1 of 14
No
No
Cele\plx-1
1 of 14
No
No
Cele\plx-2
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (7)
Agam\AgaP_AGAP005742
11 of 12
Yes
Yes
Agam\AgaP_AGAP008656
5 of 12
No
No
Agam\AgaP_AGAP002424
2 of 12
No
No
Agam\AgaP_AGAP006634
2 of 12
No
No
Agam\AgaP_AGAP006636
2 of 12
No
No
Agam\AgaP_AGAP000064
1 of 12
No
No
Agam\AgaP_AGAP011139
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (0)
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Sema1b. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (6)
Sema1a
11 of 13
Sema2a
3 of 13
Sema2b
3 of 13
Sema5c
3 of 13
PlexA
1 of 13
PlexB
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 2 )
    Human Ortholog
    Disease
    Evidence
    References
    SEMA4A; semaphorin 4A
    model of  cone-rod dystrophy 10
    IEA
    (FlyBase, 2019-)
    model of  retinitis pigmentosa 35
    IEA
    (FlyBase, 2019-)
    Modifiers Based on Experimental Evidence ( 1 )
    Allele
    Disease
    Interaction
    References
    Sema1bKK104666
    exacerbates  atypical teratoid rhabdoid tumor
    modeled by Snr1KK101602
    (Tegeder et al., 2019)
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    SEMA6A; semaphorin 6A
    9 of 14
    605885
        SEMA6B; semaphorin 6B
        9 of 14
        608873
          SEMA6D; semaphorin 6D
          9 of 14
          609295
              SEMA6C; semaphorin 6C
              8 of 14
              609294
                  SEMA3A; semaphorin 3A
                  4 of 14
                  603961
                  SEMA3B; semaphorin 3B
                  4 of 14
                  601281
                      SEMA3C; semaphorin 3C
                      4 of 14
                      602645
                          SEMA3D; semaphorin 3D
                          4 of 14
                          609907
                              SEMA3F; semaphorin 3F
                              4 of 14
                              601124
                                  SEMA3G; semaphorin 3G
                                  4 of 14
                                  620997
                                      SEMA3E; semaphorin 3E
                                      3 of 14
                                      608166
                                          SEMA4A; semaphorin 4A
                                          3 of 14
                                          607292
                                           
                                          SEMA4B; semaphorin 4B
                                          3 of 14
                                          617029
                                              SEMA4C; semaphorin 4C
                                              3 of 14
                                              604462
                                                  SEMA4D; semaphorin 4D
                                                  3 of 14
                                                  601866
                                                      SEMA4F; ssemaphorin 4F
                                                      3 of 14
                                                      603706
                                                          SEMA4G; semaphorin 4G
                                                          3 of 14
                                                          618991
                                                              SEMA7A; semaphorin 7A (JohnMiltonHagen blood group)
                                                              3 of 14
                                                              607961
                                                                Functional Complementation Data
                                                                Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                                                Interactions
                                                                Summary of Physical Interactions
                                                                Summary of Genetic Interactions
                                                                Interaction Browsers
                                                                View in FlyBase Interactions Browser   View in MIST tool (external link)
                                                                Please look at the allele data for full details of the genetic interactions
                                                                Starting gene(s)
                                                                Interaction type
                                                                Interacting gene(s)
                                                                Reference
                                                                Starting gene(s)
                                                                Interaction type
                                                                Interacting gene(s)
                                                                Reference
                                                                Snr1
                                                                suppressible
                                                                Sema1b
                                                                (Tegeder et al., 2019)
                                                                External Data
                                                                Linkouts
                                                                BioGRID - A database of protein and genetic interactions.
                                                                DroID - A comprehensive database of gene and protein interactions.
                                                                MIST (protein-protein) - An integrated Molecular Interaction Database
                                                                Pathways
                                                                Signaling Pathways (FlyBase)
                                                                Metabolic Pathways
                                                                FlyBase
                                                                External Links
                                                                External Data
                                                                Class of Gene
                                                                Genomic Location and Detailed Mapping Data
                                                                Chromosome (arm)
                                                                2R
                                                                Recombination map
                                                                2-83
                                                                Cytogenetic map
                                                                54D4-54D5
                                                                Sequence location
                                                                FlyBase Computed Cytological Location
                                                                Cytogenetic map
                                                                Evidence for location
                                                                54D4-54D5
                                                                Limits computationally determined from genome sequence between P{PZ}l(2)1050510505 and P{lacW}l(2)k07509k07509&P{EP}CG10934EP538
                                                                Experimentally Determined Cytological Location
                                                                Cytogenetic map
                                                                Notes
                                                                References
                                                                Experimentally Determined Recombination Data
                                                                Location

                                                                2-83

                                                                (FlyBase, 2016)

                                                                2-86.5

                                                                (Comeron et al., 2012)
                                                                Left of (cM)
                                                                Right of (cM)
                                                                Notes
                                                                Stocks and Reagents
                                                                Stocks (11)
                                                                Genomic Clones (31)
                                                                cDNA Clones (109)
                                                                 

                                                                Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                                                                cDNA clones, fully sequenced
                                                                BDGP DGC clones
                                                                Other clones
                                                                Drosophila Genomics Resource Center cDNA clones

                                                                For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                                                cDNA Clones, End Sequenced (ESTs)
                                                                BDGP DGC clones
                                                                Other clones
                                                                RNAi and Array Information
                                                                Linkouts
                                                                DRSC - Results frm RNAi screens
                                                                Antibody Information
                                                                Laboratory Generated Antibodies
                                                                 
                                                                Commercially Available Antibodies
                                                                 
                                                                Cell Line Information
                                                                Publicly Available Cell Lines
                                                                 
                                                                  Other Stable Cell Lines
                                                                   
                                                                    Other Comments
                                                                    Relationship to Other Genes
                                                                    Source for database merge of

                                                                    Source for merge of: Sema-1b BcDNA:GH03186

                                                                    (FlyBase, 1996-)
                                                                    Additional comments

                                                                    Source for merge of Sema-1b BcDNA:GH03186 was sequence comparison ( date:000114 ).

                                                                    (FlyBase, 1996-)
                                                                    Nomenclature History
                                                                    Source for database identify of

                                                                    Source for identity of: Sema1b Sema-1b

                                                                    (FlyBase, 2009-)
                                                                    Nomenclature comments
                                                                    Etymology
                                                                    Synonyms and Secondary IDs (15)
                                                                    Datasets (0)
                                                                    Study focus (0)
                                                                    Experimental Role
                                                                    Project
                                                                    Project Type
                                                                    Title
                                                                    Study result (0)
                                                                    Result
                                                                    Result Type
                                                                    Title
                                                                    External Crossreferences and Linkouts ( 55 )
                                                                    Sequence Crossreferences
                                                                    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                                                    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                                                    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                                                                    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                                                    UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                                                                    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                                                                    Other crossreferences
                                                                    AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                                                                    DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                                                                    EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                                                                    FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                                                                    FlyMine - An integrated database for Drosophila genomics
                                                                    InterPro - A database of protein families, domains and functional sites
                                                                    KEGG Genes - Molecular building blocks of life in the genomic space.
                                                                    MARRVEL_MODEL - MARRVEL (model organism gene)
                                                                    PDB - An information portal to biological macromolecular structures
                                                                    Linkouts
                                                                    BioGRID - A database of protein and genetic interactions.
                                                                    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                                                                    DroID - A comprehensive database of gene and protein interactions.
                                                                    DRSC - Results frm RNAi screens
                                                                    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                                                    FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                                                                    FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                                                                    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                                                                    Flygut - An atlas of the Drosophila adult midgut
                                                                    FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
                                                                    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                                                                    MIST (protein-protein) - An integrated Molecular Interaction Database
                                                                    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                                                    References (81)