Ig domain cell adhesion molecule - ligand for Beaten path Ia - axon guidance
Please see the JBrowse view of Dmel\side for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
Gene model reviewed during 5.40
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\side using the Feature Mapper tool.
side is expressed dynamically in neurons and muscles during embryogenesis. It is a cell surface marker that appears to direct the path of motor axons. At embryonic stage 12, side is expressed in a belt-like pattern along the ventral midline. The aCC neuron develops next to side-expressing cells. By stage 13, the side pattern has turned into a triangular pattern, with tips pointing away from the midline. The motor axons of the intersegmental nerve project along the anterior edge of each triangle. Axons of the segmental nerve grow along the posterior edge. The motor axons are guided directly toward the exit junction and ganglionic branch of the trachea. At the trachea, motor axons fasciculate with side-positive afferent sensory axons exactly at the lateral bidendritic neuron. When the intersegmental nerve has reached the end of the sensory tracks at the bidendritic neurons, side expression in the sensory neurons is not still detectable but instead is observed in muscle fibers. The side-expressing muscles are thought to attract the motor neurons, thus causing them to leave the sensory tracks. In general, cells and tissues located ahead of motor neuron growth cones express side.
GBrowse - Visual display of RNA-Seq signals
View Dmel\side in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Annotations CG12510, CG13975, CG13979 merged as CG31062 in release 3 of the genome annotation.
side is essential for motor axons to leave the motor nerves and enter their muscle targets.
Mutant alleles are defective in motor neuron defasciculation.
