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Gene Dmel\vkg

General Information
Symbol	Dmel\vkg	Species	D. melanogaster
Name	viking	Annotation symbol	CG16858
Feature type	protein_coding_gene	FlyBase ID	FBgn0016075
Gene Model Status	Current	Stock availability	10 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map	2-
Cytogenetic map	25C1-25C1	Sequence location	2L:5,012,144..5,028,191 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene viking is referred to in FlyBase by the symbol Dmel\vkg (CG16858, FBgn0016075). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: extracellular matrix structural constituent. There is experimental evidence that it is involved in the biological process: anterior Malpighian tubule development; Malpighian tubule morphogenesis; skeletal muscle tissue development. 36 alleles are reported. The phenotypes of these alleles are annotated with: embryonic anterior Malpighian tubule; A1-7 segment border muscle. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: C-type lectin fold; Collagen IV, non-collagenous; Collagen triple helix repeat. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult heart, adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, larval hindgut, larval fat body, larval salivary gland, larval trachea, adult ovary, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1639229_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of vkg. Gene sequence location is 2L:5012144..5028191.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 25C1-25C1   Limits computationally determined from genome sequence between P{lacW}l(2)k10001k10001 and P{lacW}vkgk16721&P{lacW}Cg25Ck00405
Experimentally Determined Cytological Location
Cytogenetic map Notes References 25C-25C     (Dearolf, 1996.7.26) 25C1-25C2   (determined by in situ hybridisation)   (Spradling et al., 1999) 25C-25C     (Gellon et al., 1997) 25C-25C   (determined by in situ hybridisation)   (Rodriguez et al., 1996) 25C-25C     (Kimbrell, 1996.4.28) 25C-25C     (Chen et al., 1996) 25C1-25C2     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location	2- (Chen et al., 1996)
Left of (cM)
Right of (cM)
Notes	Maps immediately 5' to Cg25C. (Chen et al., 1996)
Gene Model & Products
Please see the GBrowse view of Dmel\vkg for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) vkg-RA FBtr0079036  NM_057842   6376   1940 vkg-RB FBtr0333540  NM_001273142   6355   1940 vkg-RC FBtr0333541  NM_001273143   6430   1940
Additional Transcript Data & Comments
Reported size (kB)	6.337 (longest cDNA) (Yasothornsrikul et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein vkg-PA   FBpp0078672   193.8   1940   6.36     NP_477190   AAF52203 vkg-PB   FBpp0305720   193.8   1940   6.36     NP_001260071   AGB92607 vkg-PC   FBpp0305721   193.8   1940   6.36     NP_001260072   AGB92608
Additional Polypeptide Data & Comments
Reported size (kDa)	1761 (aa) (Yasothornsrikul et al., 1997)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Collagen IV, non-collagenous (IPR001442) Collagen triple helix repeat (IPR008160) C-type lectin fold (IPR016187)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA697260   AA697923   AA698019   AE014134 AAF52203   AC008233   AE014134 AGB92607   AE014134 AGB92608   AI134141   AI389769   AQ025683   AQ026106   AQ026115   AQ073262   BG632627   BI230172   BI351788   BI351796   BI351817   BI351916   BI352133   BI354559   BI355364   BI355397   BI355866   BI485311   BI579848   BT081404   CK134581   CO179040   CO188041   CO196496   CO266433   CO269341   CO272501   CO274139   CO275374   CO275469   CO283297   CO289061   CO293936   CO315437   CO317770   CO321146   CO322472   CO324779   CO327357   CO327848   CO328566   CO332471   CO333579   CZ473309   EC066689   EC069198   EC072151   EC082395   EC085668   EC091115   EC195884   EC196937   EC198124   EC199516   EC209432   EC209532   EC211906   EC216749   EC220704   EC222391   EC228956   EC233262   EC240605   EC243062   EC244880   EC246807   EC247381   EC258044   EC259207   ES696088   ES696325   U65431 AAB64082
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VMV5 O18407
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 12   cardiogenic mesoderm   (Fisher et al., 2012) pericardial cell primordium   (Fisher et al., 2012) Comment:reported as pericardial cell specific anlage plasmatocyte primordium   (Fisher et al., 2012) Comment:reported as plasmatocytes anlage embryonic stage 13 -- 16   embryonic/larval circulatory system   (Fisher et al., 2012) embryonic/larval fat body   (Fisher et al., 2012) embryonic/larval pericardial cell   (Fisher et al., 2012) plasmatocyte   (Fisher et al., 2012) embryonic stage 15 -- 16   embryonic/larval hemocyte   (Yasothornsrikul et al., 1997) embryonic stage 16 -- 17   embryonic/larval fat body   (Yasothornsrikul et al., 1997) first instar larval stage   embryonic/larval fat body   (Yasothornsrikul et al., 1997)
Additional Descriptive Data
	vkg and Cg25C transcripts are both detected in fat bodies and hemocytes in late embryogenesis, and fat bodies in first larval instar. (Yasothornsrikul et al., 1997)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006)
Expression Deduced from Reporters
Reporter: P{lacW}vkgk07138 Stage Tissue/Position (including subcellular localization) Reference embryonic stage   embryonic/larval hemocyte   (Rodriguez et al., 1996) embryonic stage -- larval stage & adult stage   fat body   (Rodriguez et al., 1996) adult stage   adult oenocyte   (Rodriguez et al., 1996) Reporter: P{lacW}vkgk09511 Stage Tissue/Position (including subcellular localization) Reference embryonic stage   embryonic/larval hemocyte   (Rodriguez et al., 1996) embryonic stage -- larval stage & adult stage   fat body   (Rodriguez et al., 1996) larval stage   embryonic/larval central nervous system   (Rodriguez et al., 1996) Reporter: P{lacW}vkgk13802 Stage Tissue/Position (including subcellular localization) Reference embryonic stage   embryonic/larval hemocyte   (Rodriguez et al., 1996) embryonic stage -- larval stage & adult stage   fat body   (Rodriguez et al., 1996) larval stage   embryonic/larval central nervous system   (Rodriguez et al., 1996) Reporter: P{lacW}vkgk16721 Stage Tissue/Position (including subcellular localization) Reference embryonic stage   embryonic/larval hemocyte   (Rodriguez et al., 1996) embryonic stage -- larval stage & adult stage   fat body   (Rodriguez et al., 1996) Reporter: P{PZ}vkg01209 Stage Tissue/Position (including subcellular localization) Reference embryonic stage   gastric caecum   (Jackle and Janning, 1998.8.10) embryonic/larval proventriculus   (Jackle and Janning, 1998.8.10) embryonic/larval pericardial cell   (Jackle and Janning, 1998.8.10) embryonic/larval fat body   (Jackle and Janning, 1998.8.10) embryonic/larval midgut   (Jackle and Janning, 1998.8.10) embryonic/larval hemocyte   (Jackle and Janning, 1998.8.10) anterior embryonic/larval midgut   (Jackle and Janning, 1998.8.10) posterior embryonic/larval midgut   (Jackle and Janning, 1998.8.10) mesoderm   (Jackle and Janning, 1998.8.10) wandering third instar larval stage   ring gland   (Harvie et al., 1998) embryonic/larval optic lobe   (Harvie et al., 1998) ventral nerve cord   (Harvie et al., 1998) Reporter: P{PZ}vkg06072a Stage Tissue/Position (including subcellular localization) Reference second instar larval stage -- third instar larval stage   embryonic/larval corpus allatum   (Harvie et al., 1998) wandering third instar larval stage   embryonic/larval optic lobe   (Harvie et al., 1998) ventral nerve cord   (Harvie et al., 1998) eye disc   (Harvie et al., 1998)
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system, adult heart, adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, larval hindgut, larval fat body, larval salivary gland, larval trachea, adult ovary, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain    567.3 Adult Thoracic-Abdominal Ganglion    939.6 Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body    1614.3 Adult Salivary Gland    36.4 Adult Heart    1508.775 Adult VirginFemale Spermatheca    1014.3 Adult InseminatedFemale Spermatheca    1419.2 Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass    807.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain  (567.3) Adult Thoracic-Abdominal Ganglion  (939.6) Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body  (1614.3) Adult Salivary Gland    36.4 Adult Heart  (1508.775) Adult VirginFemale Spermatheca  (1014.3) Adult InseminatedFemale Spermatheca  (1419.2) Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass  (807.8) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain    567.3 Adult Thoracic-Abdominal Ganglion    939.6 Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body  (1614.3) Adult Salivary Gland    36.4 Adult Heart  (1508.775) Adult VirginFemale Spermatheca  1014.3 Adult InseminatedFemale Spermatheca  (1419.2) Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass    807.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain    567.3 Adult Thoracic-Abdominal Ganglion    939.6 Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body    1614.3 Adult Salivary Gland    36.4 Adult Heart    1508.775 Adult VirginFemale Spermatheca    1014.3 Adult InseminatedFemale Spermatheca    1419.2 Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass    807.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain    567.3 Adult Thoracic-Abdominal Ganglion    939.6 Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body    1614.3 Adult Salivary Gland    36.4 Adult Heart    1508.775 Adult VirginFemale Spermatheca    1014.3 Adult InseminatedFemale Spermatheca    1419.2 Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass    807.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain  567.3 Adult Thoracic-Abdominal Ganglion  (939.6) Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body  (1614.3) Adult Salivary Gland    36.4 Adult Heart  (1508.775) Adult VirginFemale Spermatheca  (1014.3) Adult InseminatedFemale Spermatheca  (1419.2) Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass  807.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain    567.3 Adult Thoracic-Abdominal Ganglion    939.6 Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body  1614.3 Adult Salivary Gland    36.4 Adult Heart  1508.775 Adult VirginFemale Spermatheca  1014.3 Adult InseminatedFemale Spermatheca  1419.2 Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass    807.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    354.55 Larval Midgut    20.2 Larval Hindgut    256.3 Larval Malpighian Tubules    54.4 Larval Fat Body    443.4 Larval Salivary Gland    109.4 Larval Trachea    253.05 Larval Carcass    428.2 Adult Head    387.2 Adult Eye    75 Adult Brain    567.3 Adult Thoracic-Abdominal Ganglion    939.6 Adult Crop    64.6 Adult Midgut    6.1 Adult Hindgut    87.3 Adult Malpighian Tubules    21 Adult Fat Body    1614.3 Adult Salivary Gland    36.4 Adult Heart    1508.775 Adult VirginFemale Spermatheca    1014.3 Adult InseminatedFemale Spermatheca    1419.2 Adult Ovary    213.7 Adult Testis    43.5 Adult Male Accessory Gland    41.3 Adult Carcass    807.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    387.2   NA  Eye    75   NA  Brain    567.3   354.55  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    939.6   NA  Crop    no informative data   no informative data  Midgut    6.1   256.3  Hindgut    87.3   no informative data  Malpighian Tubules    no informative data   443.4  Fat Body    1614.3   109.4  Salivary Gland    no informative data   NA  Heart    1508.775   253.05  Trachea    NA   NA  VirginFemale Spermatheca    1014.3   NA  InseminatedFemale Spermatheca    1419.2   NA  Ovary    213.7   NA  Testis    43.5   NA  Male Accessory Gland    no informative data   428.2  Carcass    807.8 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8    28 head, virgin 1-day female    73 head, virgin 4-day female    32 head, virgin 20-day female    21 head, mated 1-day female    61 head, mated 4-day female    38 head, mated 20-day female    23 head, mated 1-day male    66 head, mated 4-day male    45 head, mated 20-day male    28 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering    85 fat body, white prepupae    15 fat body, pupae P8    35 carcass, larvae L3 wandering    13 carcass, 1-day adult    84 carcass, 4-day adult    52 carcass, 20-day adult    36 ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8  (28) head, virgin 1-day female  (73) head, virgin 4-day female  (32) head, virgin 20-day female    21 head, mated 1-day female  (61) head, mated 4-day female  (38) head, mated 20-day female    23 head, mated 1-day male  (66) head, mated 4-day male  (45) head, mated 20-day male  (28) salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering  (85) fat body, white prepupae    15 fat body, pupae P8  (35) carcass, larvae L3 wandering    13 carcass, 1-day adult  (84) carcass, 4-day adult  (52) carcass, 20-day adult  (36) ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8    28 head, virgin 1-day female    73 head, virgin 4-day female    32 head, virgin 20-day female    21 head, mated 1-day female    61 head, mated 4-day female    38 head, mated 20-day female    23 head, mated 1-day male    66 head, mated 4-day male    45 head, mated 20-day male    28 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering    85 fat body, white prepupae    15 fat body, pupae P8    35 carcass, larvae L3 wandering    13 carcass, 1-day adult    84 carcass, 4-day adult    52 carcass, 20-day adult    36 ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8    28 head, virgin 1-day female    73 head, virgin 4-day female    32 head, virgin 20-day female    21 head, mated 1-day female    61 head, mated 4-day female    38 head, mated 20-day female    23 head, mated 1-day male    66 head, mated 4-day male    45 head, mated 20-day male    28 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering    85 fat body, white prepupae    15 fat body, pupae P8    35 carcass, larvae L3 wandering    13 carcass, 1-day adult    84 carcass, 4-day adult    52 carcass, 20-day adult    36 ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8    28 head, virgin 1-day female    73 head, virgin 4-day female    32 head, virgin 20-day female    21 head, mated 1-day female    61 head, mated 4-day female    38 head, mated 20-day female    23 head, mated 1-day male    66 head, mated 4-day male    45 head, mated 20-day male    28 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering    85 fat body, white prepupae    15 fat body, pupae P8    35 carcass, larvae L3 wandering    13 carcass, 1-day adult    84 carcass, 4-day adult    52 carcass, 20-day adult    36 ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8  28 head, virgin 1-day female  (73) head, virgin 4-day female  32 head, virgin 20-day female    21 head, mated 1-day female  (61) head, mated 4-day female  (38) head, mated 20-day female    23 head, mated 1-day male  (66) head, mated 4-day male  (45) head, mated 20-day male  28 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering  (85) fat body, white prepupae    15 fat body, pupae P8  (35) carcass, larvae L3 wandering    13 carcass, 1-day adult  (84) carcass, 4-day adult  (52) carcass, 20-day adult  (36) ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8    28 head, virgin 1-day female    73 head, virgin 4-day female    32 head, virgin 20-day female    21 head, mated 1-day female    61 head, mated 4-day female    38 head, mated 20-day female    23 head, mated 1-day male    66 head, mated 4-day male    45 head, mated 20-day male    28 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering    85 fat body, white prepupae    15 fat body, pupae P8    35 carcass, larvae L3 wandering    13 carcass, 1-day adult    84 carcass, 4-day adult    52 carcass, 20-day adult    36 ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    7 central nervous system, pupae P8    28 head, virgin 1-day female    73 head, virgin 4-day female    32 head, virgin 20-day female    21 head, mated 1-day female    61 head, mated 4-day female    38 head, mated 20-day female    23 head, mated 1-day male    66 head, mated 4-day male    45 head, mated 20-day male    28 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    2 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    15 digestive system, 4-day adult    7 digestive system, 20-day adult    3 fat body, larvae L3 wandering    85 fat body, white prepupae    15 fat body, pupae P8    35 carcass, larvae L3 wandering    13 carcass, 1-day adult    84 carcass, 4-day adult    52 carcass, 20-day adult    36 ovary, virgin 4-day female    14 ovary, mated 4-day female    13 testis, mated 4-day male    3 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    29 embryo 12-14hr    62 embryo 14-16hr    331 embryo 16-18hr    515 embryo 18-20hr    830 embryo 20-22hr    536 embryo 22-24hr    414 larva L1    380 larva L2    397 larva L3 12hr old    460 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP    31 pupae 3d postWPP    116 pupae 4d postWPP    88 adult male 01day    74 adult male 05day    34 adult male 30day    17 adult female 01day    108 adult female 05day    36 adult female 30day    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr  (29) embryo 12-14hr  (62) embryo 14-16hr  (331) embryo 16-18hr  (515) embryo 18-20hr  (830) embryo 20-22hr  (536) embryo 22-24hr  (414) larva L1  (380) larva L2  (397) larva L3 12hr old  (460) larva L3 puffstage 1-2  (52) larva L3 puffstage 3-6  (31) larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP  (31) pupae 3d postWPP  (116) pupae 4d postWPP  (88) adult male 01day  (74) adult male 05day  (34) adult male 30day    17 adult female 01day  (108) adult female 05day  (36) adult female 30day  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    29 embryo 12-14hr    62 embryo 14-16hr  (331) embryo 16-18hr  (515) embryo 18-20hr  (830) embryo 20-22hr  (536) embryo 22-24hr  (414) larva L1  (380) larva L2  (397) larva L3 12hr old  (460) larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP    31 pupae 3d postWPP  (116) pupae 4d postWPP    88 adult male 01day    74 adult male 05day    34 adult male 30day    17 adult female 01day  (108) adult female 05day    36 adult female 30day    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    29 embryo 12-14hr    62 embryo 14-16hr    331 embryo 16-18hr    515 embryo 18-20hr    830 embryo 20-22hr    536 embryo 22-24hr    414 larva L1    380 larva L2    397 larva L3 12hr old    460 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP    31 pupae 3d postWPP    116 pupae 4d postWPP    88 adult male 01day    74 adult male 05day    34 adult male 30day    17 adult female 01day    108 adult female 05day    36 adult female 30day    35 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    29 embryo 12-14hr    62 embryo 14-16hr    331 embryo 16-18hr    515 embryo 18-20hr    830 embryo 20-22hr    536 embryo 22-24hr    414 larva L1    380 larva L2    397 larva L3 12hr old    460 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP    31 pupae 3d postWPP    116 pupae 4d postWPP    88 adult male 01day    74 adult male 05day    34 adult male 30day    17 adult female 01day    108 adult female 05day    36 adult female 30day    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr  29 embryo 12-14hr  (62) embryo 14-16hr  (331) embryo 16-18hr  (515) embryo 18-20hr  (830) embryo 20-22hr  (536) embryo 22-24hr  (414) larva L1  (380) larva L2  (397) larva L3 12hr old  (460) larva L3 puffstage 1-2  (52) larva L3 puffstage 3-6  31 larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP  31 pupae 3d postWPP  (116) pupae 4d postWPP  (88) adult male 01day  (74) adult male 05day  (34) adult male 30day    17 adult female 01day  (108) adult female 05day  (36) adult female 30day  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    29 embryo 12-14hr    62 embryo 14-16hr  (331) embryo 16-18hr  (515) embryo 18-20hr  (830) embryo 20-22hr  (536) embryo 22-24hr  (414) larva L1  (380) larva L2  (397) larva L3 12hr old  (460) larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP    31 pupae 3d postWPP  116 pupae 4d postWPP    88 adult male 01day    74 adult male 05day    34 adult male 30day    17 adult female 01day  108 adult female 05day    36 adult female 30day    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    1 embryo 04-06hr    1 embryo 06-08hr    7 embryo 08-10hr    12 embryo 10-12hr    29 embryo 12-14hr    62 embryo 14-16hr    331 embryo 16-18hr    515 embryo 18-20hr    830 embryo 20-22hr    536 embryo 22-24hr    414 larva L1    380 larva L2    397 larva L3 12hr old    460 larva L3 puffstage 1-2    52 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    12 white prepupae new    13 white prepupae 12hr    17 white prepupae 24hr    12 pupae 2d postWPP    31 pupae 3d postWPP    116 pupae 4d postWPP    88 adult male 01day    74 adult male 05day    34 adult male 30day    17 adult female 01day    108 adult female 05day    36 adult female 30day    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    1277 embryonic 1182-4H    228 embryonic GM2    86 embryonic Kc167    33 embryonic S1    11 embryonic S3    12 leg disc CME L1    1187 wing disc CME-W2    60 wing disc ML-DmD8    201 wing disc ML-DmD9    213 wing disc ML-DmD16-c3    280 wing disc ML-DmD21    35 wing disc ML-DmD32    1156 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    633 antennal disc ML-DmD20-c5    53 mixed discs ML-DmD4-c1    544 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    4 ovary fGS/OSS    128 ovary OSC    4 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (93) Schneider line 2 Sg4  (1277) embryonic 1182-4H  (228) embryonic GM2  (86) embryonic Kc167  (33) embryonic S1    11 embryonic S3    12 leg disc CME L1  (1187) wing disc CME-W2  (60) wing disc ML-DmD8  (201) wing disc ML-DmD9  (213) wing disc ML-DmD16-c3  (280) wing disc ML-DmD21  (35) wing disc ML-DmD32  (1156) haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  (633) antennal disc ML-DmD20-c5  (53) mixed discs ML-DmD4-c1  (544) CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2  (71) tumorous blood cells mbn2    4 ovary fGS/OSS  (128) ovary OSC    4 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4  (1277) embryonic 1182-4H  (228) embryonic GM2    86 embryonic Kc167    33 embryonic S1    11 embryonic S3    12 leg disc CME L1  (1187) wing disc CME-W2    60 wing disc ML-DmD8  (201) wing disc ML-DmD9  (213) wing disc ML-DmD16-c3  (280) wing disc ML-DmD21    35 wing disc ML-DmD32  (1156) haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  (633) antennal disc ML-DmD20-c5    53 mixed discs ML-DmD4-c1  (544) CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    4 ovary fGS/OSS  (128) ovary OSC    4 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    1277 embryonic 1182-4H    228 embryonic GM2    86 embryonic Kc167    33 embryonic S1    11 embryonic S3    12 leg disc CME L1    1187 wing disc CME-W2    60 wing disc ML-DmD8    201 wing disc ML-DmD9    213 wing disc ML-DmD16-c3    280 wing disc ML-DmD21    35 wing disc ML-DmD32    1156 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    633 antennal disc ML-DmD20-c5    53 mixed discs ML-DmD4-c1    544 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    4 ovary fGS/OSS    128 ovary OSC    4 ovary OSS    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    1277 embryonic 1182-4H    228 embryonic GM2    86 embryonic Kc167    33 embryonic S1    11 embryonic S3    12 leg disc CME L1    1187 wing disc CME-W2    60 wing disc ML-DmD8    201 wing disc ML-DmD9    213 wing disc ML-DmD16-c3    280 wing disc ML-DmD21    35 wing disc ML-DmD32    1156 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    633 antennal disc ML-DmD20-c5    53 mixed discs ML-DmD4-c1    544 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    4 ovary fGS/OSS    128 ovary OSC    4 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (93) Schneider line 2 Sg4  (1277) embryonic 1182-4H  (228) embryonic GM2  (86) embryonic Kc167  (33) embryonic S1    11 embryonic S3    12 leg disc CME L1  (1187) wing disc CME-W2  (60) wing disc ML-DmD8  (201) wing disc ML-DmD9  (213) wing disc ML-DmD16-c3  (280) wing disc ML-DmD21  (35) wing disc ML-DmD32  (1156) haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  (633) antennal disc ML-DmD20-c5  (53) mixed discs ML-DmD4-c1  (544) CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2  (71) tumorous blood cells mbn2    4 ovary fGS/OSS  (128) ovary OSC    4 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4  (1277) embryonic 1182-4H  (228) embryonic GM2    86 embryonic Kc167    33 embryonic S1    11 embryonic S3    12 leg disc CME L1  (1187) wing disc CME-W2    60 wing disc ML-DmD8  (201) wing disc ML-DmD9  (213) wing disc ML-DmD16-c3  (280) wing disc ML-DmD21    35 wing disc ML-DmD32  (1156) haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  (633) antennal disc ML-DmD20-c5    53 mixed discs ML-DmD4-c1  (544) CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    4 ovary fGS/OSS  128 ovary OSC    4 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    93 Schneider line 2 Sg4    1277 embryonic 1182-4H    228 embryonic GM2    86 embryonic Kc167    33 embryonic S1    11 embryonic S3    12 leg disc CME L1    1187 wing disc CME-W2    60 wing disc ML-DmD8    201 wing disc ML-DmD9    213 wing disc ML-DmD16-c3    280 wing disc ML-DmD21    35 wing disc ML-DmD32    1156 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    633 antennal disc ML-DmD20-c5    53 mixed discs ML-DmD4-c1    544 CNS ML-DmBG1-c1    2 CNS ML-DmBG2-c2    71 tumorous blood cells mbn2    4 ovary fGS/OSS    128 ovary OSC    4 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    55 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    60 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    42 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    44 Ethanol 10% 3 hrs, larvae L3    53 Caffeine 1.5 mg/ml 4 hrs, larvae L3    32 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    35 Rotenone 8 μg 12 hrs, larvae L3    107 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult  (44) Cadmium 50 mM 6 hrs, larvae L3  (44) Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult  (55) Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3  (60) Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3  (42) Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3  (44) Ethanol 10% 3 hrs, larvae L3  (53) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (32) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult  (31) Rotenone 2 μg 12 hrs, larvae L3  (35) Rotenone 8 μg 12 hrs, larvae L3  (107) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    55 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    60 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    42 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    44 Ethanol 10% 3 hrs, larvae L3    53 Caffeine 1.5 mg/ml 4 hrs, larvae L3    32 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    35 Rotenone 8 μg 12 hrs, larvae L3  107 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    55 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    60 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    42 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    44 Ethanol 10% 3 hrs, larvae L3    53 Caffeine 1.5 mg/ml 4 hrs, larvae L3    32 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    35 Rotenone 8 μg 12 hrs, larvae L3    107 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    55 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    60 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    42 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    44 Ethanol 10% 3 hrs, larvae L3    53 Caffeine 1.5 mg/ml 4 hrs, larvae L3    32 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    35 Rotenone 8 μg 12 hrs, larvae L3    107 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult  (44) Cadmium 50 mM 6 hrs, larvae L3  (44) Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult  (55) Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3  (60) Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3  (42) Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3  (44) Ethanol 10% 3 hrs, larvae L3  (53) Caffeine 1.5 mg/ml 4 hrs, larvae L3  32 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult  31 Rotenone 2 μg 12 hrs, larvae L3  (35) Rotenone 8 μg 12 hrs, larvae L3  (107) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    55 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    60 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    42 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    44 Ethanol 10% 3 hrs, larvae L3    53 Caffeine 1.5 mg/ml 4 hrs, larvae L3    32 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    35 Rotenone 8 μg 12 hrs, larvae L3  107 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    14 heat shock, 4-day adult    44 Cadmium 50 mM 6 hrs, larvae L3    44 Cadmium 50 mM 12 hrs, larvae L3    9 Cadmium 50 mM 48 hrs, 4-day adult    55 Cadmium 100 mM 48 hrs, 4-day adult    6 Copper 0.5 mM 12 hrs, larvae L3    60 Copper 15 mM 48 hrs, 4-day adult    6 Zinc 5 mM 12 hrs, larvae L3    42 Zinc 4.5 mM 48 hrs, 4-day adult    16 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    44 Ethanol 10% 3 hrs, larvae L3    53 Caffeine 1.5 mg/ml 4 hrs, larvae L3    32 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    14 Paraquat 5 mM 48 hrs, 4-day adult    22 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    35 Rotenone 8 μg 12 hrs, larvae L3    107 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_20 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • RE68619 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0016075 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16858-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for vkg Stages(s) 4-6 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal (with vkgb-14) vkgb-35 vkgsz-14 lethal (with vkgb-35) vkgb-14 vkgsz-14 lethal (with vkgsz-14) vkgb-14 vkgb-35 lethal | recessive vkg01158 vkg01209 vkgb-14 vkgb-35 vkghsneo80 vkgk00236 vkgk01701 vkgk07138 vkgk08809 vkgk09511 vkgk13802 vkgk16502 vkgk16721 vkgsz-6 vkgsz-14 vkgsz-78 viable vkgCC00791 viable, with Scer\GAL4pnr-MD237 vkgGD5246 Other Phenotypes Allele hypoactive vkgk13802 vkgk16721 locomotor behavior defective vkgk13802 vkgk16721 short lived vkgk13802 vkgk16721 Phenotype manifest in Allele A1-7 segment border muscle, with Scer\GAL4how-24B vkgNIG.16858R embryonic anterior Malpighian tubule vkgk00236 embryonic anterior Malpighian tubule, with Scer\GAL4crq.PO, Scer\GAL4srp.Hemo vkgKK111668
Classical Alleles ( 33 )
For All Classical Alleles Show
Allele of vkg Class Mutagen Stocks Known lesion vkgk00236 P-element activity 2 -- vkg01209 P-element activity 1 -- vkgd03348 P-element activity 1 -- vkgk01701 P-element activity 1 -- vkgk07138 P-element activity 1 -- vkgk08809 P-element activity 1 -- vkgk16721 P-element activity 1 -- vkg01018 P-element activity 0 -- vkg01158 P-element activity 0 -- vkg01864a P-element activity 0 -- vkg06072a P-element activity 0 -- vkg07776a P-element activity 0 -- vkg177 0 -- vkg197 P-element activity 0 Yes vkg228 0 -- vkg235 0 -- vkg30 0 -- vkg319 0 -- vkgb-14 0 -- vkgb-35 0 -- vkgCC00791 P-element activity 0 Yes vkgG00454 P-element activity 0 Yes vkgG205 P-element activity 0 -- vkgG454 P-element activity 0 Yes vkghsneo80 0 -- vkgk09511 P-element activity 0 Yes vkgk13802 P-element activity 0 -- vkgk16502 P-element activity 0 -- vkgp1003-83 0 -- vkgP10038 0 -- vkgsz-14 0 -- vkgsz-6 0 -- vkgsz-78 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of vkg Class Mutagen Stocks Known lesion vkgGD5246 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes vkgKK111668 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes vkgNIG.16858R in vitro construct - regulatory fusion in vitro construct - RNAi 0 --
Aneuploid Aberrations
Not disrupted in	Df(2L)cl-h3 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2L)sc19-8 (BDGP Project Members, 1994-1999) Df(2L)tkv2 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2L)tkv3 (BDGP Project Members, 1994-1999)
Disrupted in	Df(2L)BSC51 (Deal and Cook, 2004.5.27) Df(2L)BSC172 (Christensen and Cook, 2006.8.29) Df(2L)ED256 (Mathew et al., 2009) Df(2L)ED258 (Mathew et al., 2009) Df(2L)ED260 (Mathew et al., 2009) Df(2L)ED262 (Mathew et al., 2009) Df(2L)Exel7022 (Ryder, 2004.4.26) Df(2L)TW161 (BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5246} NA P{KK111668} NA characterization construct P{NIG.16858R} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}l(2)SH2169SH2169 No P{lacW}vkg197 No P{lacW}vkgk00236 No P{lacW}vkgk01701 No P{lacW}vkgk07138 No P{lacW}vkgk08809 No P{lacW}vkgk09511 No P{lacW}vkgk13802 No P{lacW}vkgk16502 No P{lacW}vkgk16721 No P{PZ}vkg01018 No P{PZ}vkg01158 No P{PZ}vkg01209 No P{PZ}vkg01864a No P{PZ}vkg06072a No P{PZ}vkg07776a No insertion of mobile activating element P{EP}EP2181 NA P{XP}vkgd03348 NA miscellaneous insertions P{PTT-GC}vkgCC00791 NA P{PTT-un1}vkgG205 NA P{PTT-un1}vkgG454 NA P{PTT-un1}vkgG00454 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
anterior Malpighian tubule development inferred from mutant phenotype (Bunt et al., 2010) Malpighian tubule morphogenesis inferred from mutant phenotype (Bunt et al., 2010) skeletal muscle tissue development inferred from mutant phenotype (Junion et al., 2007)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
extracellular matrix structural constituent inferred from electronic annotation with InterPro:IPR001442 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
collagen inferred from electronic annotation with InterPro:IPR001442 (FlyBase Curators et al., 2004-) non-traceable author statement (Dearolf, 1996.7.26) collagen type IV non-traceable author statement (Hynes and Zhao, 2000)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
vkg - A16 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Adam anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Aldh-III anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Art3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - BI-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Br140 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG1041 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG10859 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG10898 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG10907 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11158 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11200 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11210 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11395 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) vkg - CG1140 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG1142 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11437 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11703 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11723 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11876 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG11906 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG12025 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG12104 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG12121 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG12338 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG1246 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG12481 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG12608 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG1291 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG12920 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG13189 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG13630 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG13822 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG13900 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG14022 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG14024 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG14153 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG14232 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG14419 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG14590 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG14980 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG15097 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG15529 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG15643 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG15892 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG17134 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG18619 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG1889 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG1941 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG2183 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG3008 experimental knowledge based (Guruharsha et al., 2011) vkg - CG30411 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG3045 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG30467 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31265 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31475 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31548 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31633 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31637 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31798 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31810 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG31961 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG32425 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG32700 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG33145 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG33156 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG3570 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG3603 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG3835 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG3939 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG4091 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG4098 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG4198 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG4267 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG42673 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG42724 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG4306 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG43444 experimental knowledge based (Guruharsha et al., 2011) vkg - CG4955 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5080 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5096 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5516 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5548 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5757 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5776 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5792 experimental knowledge based (Guruharsha et al., 2011) vkg - CG5850 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG5888 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG6272 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG7049 experimental knowledge based (Guruharsha et al., 2011) vkg - CG7071 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG7275 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG7277 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG8003 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG8008 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG8281 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG8568 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG8680 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG9005 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG9328 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG9386 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG9512 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CG9586 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CHKov2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CSN4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CalpA anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cg25C experimental knowledge based (Guruharsha et al., 2011) vkg - Chd64 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cht2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - CkIIα-i3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cog3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cpr23B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cpr51A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cpr67B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Ctr1B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cyp28a5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cyp4p1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Cyp9b2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Ent2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Fmo-2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - GalNAc-T2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Glt experimental knowledge based (Guruharsha et al., 2011) vkg - GstE1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Gyk anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Hel25E anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Hs2st anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - IM10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - IntS12 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Inx3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Ir93a anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Kdm4A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Lac anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Lapsyn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Lcp3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Mec2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Mfe2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Mlc1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - ND42 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - ND75 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Obp56e anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Odc1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Osi18 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Pa1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Pabp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Pdf anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Pi3K68D experimental knowledge based (Guruharsha et al., 2011) vkg - Pi4KIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Pis anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Pnn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Prosα3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Prosα7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Prosβ4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Prosβ5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Prosβ7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Rb97D experimental knowledge based (Guruharsha et al., 2011) vkg - Reg-5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Rpb5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Ser7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Spred anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Syx18 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - TBPH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Thiolase anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Tim8 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Tpc2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - TpnC41C anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Tre1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Tret1-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Tudor-SN anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - TwdlT anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - UbcD4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Ugt58Fa anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Vap-33-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Vti1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - Wsck anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - alrm anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - blw anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - boca experimental knowledge based (Guruharsha et al., 2011) vkg - bun anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - cnc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - dgrn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - dikar anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - dlg1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - dysb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - fau anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - hgo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - hrg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - lola anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - lolal anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - mRpL22 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - mfrn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - mtTFB2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - nmo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - numb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - p130CAS anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - sgg anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - shrb anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - soti anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - toe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - twin anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - vir-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - vps24 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - wda anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) vkg - wgn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions vkg allele Gene References vkg30 Dfd (Gellon et al., 1997) vkg177 Dfd (Gellon et al., 1997) peb (Wilk et al., 2004) vkg228 Dfd (Gellon et al., 1997) vkg235 Dfd (Gellon et al., 1997) vkg319 Dfd (Gellon et al., 1997) vkg01209 peb (Wilk et al., 2004) zip (Halsell and Kiehart, 1998) vkgk00236 peb (Wilk et al., 2004) vkgk07138 peb (Wilk et al., 2004) vkgk09511 zip (Halsell and Kiehart, 1998) unspecified Cg25C (Gellon et al., 1997) LanA (Gellon et al., 1997) peb (Wilk et al., 2004) sli (MacMullin and Jacobs, 2006)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59907 DroID - A comprehensive database of gene and protein interactions. • FBgn0016075 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33726
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD22666 Drosophila erecta Dere\GG24325 Drosophila yakuba Dyak\GE18704 Drosophila ananassae Dana\GF14161 Drosophila pseudoobscura pseudoobscura Dpse\GA14182 Drosophila persimilis Dper\GL26480 Drosophila willistoni Dwil\GK24152 Drosophila virilis Dvir\GJ10166 Drosophila mojavensis Dmoj\GI15691 Drosophila grimshawi Dgri\GH10272
Stocks & Reagents
Stocks Listed in FlyBase ( 10 )
Bloomington	10473 y1 w67c23; P{lacW}vkgk00236 11003 P{PZ}vkg01209 cn1/CyO; ry506
Harvard	- P{XP}vkgd03348
Kyoto	102207 y1 w67c23 ; P{lacW}vkgk01701 / CyO 102534 y1 w67c23 ; P{lacW}vkgk07138 / CyO 102667 y1 w67c23 ; P{lacW}vkgk08809 / CyO 103033 y1 w67c23 ; P{lacW}vkgk16721 / CyO 111122 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{lacW}vkgk00236 P{neoFRT}40A/CyO y+
VDRC	v106812 P{KK111668}VIE-260B v16986 w1118; P{GD5246}v16986
Genomic Clones ( 1 )
	BACR13M11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 43 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	MIP05925
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH21027 GM09574 GM15192 GM16128 GM16155 GM16234 GM16814 GM18005 GM27263 GM30537 GM30632 GM32646 HL03465 HL03638 RE73938
Other clones	164692 CK01.13A.C3 CK01.116B.A2 EK004925 EK036414 EK058249 EK070017 EK094155 EK107423 EK113329 EK117326 EK117650 EK146419 EK162812 EK188216 EK194826 EK205205 EK261501 EK269036 EK290408 EK290864 EK303542 EK307334 EP06834 EP08134 GH11516 RE68619
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0016075 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33726
Antibody Information
Other Information
Discoverer
Etymology
	The expression in immune tissues that are involved in both attack and defense, and the persistence of the few survivors as larvae led to the gene being named "viking". (Rodriguez et al., 1996)
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland. (Harvie et al., 1998) Identified in a screen for modifiers of the Dfd13/Dfd3 mutant phenotype. Shows no interaction with the Pc mutant phenotype. (Gellon et al., 1997) vkg has been cloned and characterised. (Yasothornsrikul et al., 1997) May be the same as Cg25C. (Chen et al., 1996) Identified in an enhancer-trap screen for insertions expressed in the fat body and haemocytes. May encode a collagen. (Chen et al., 1996) vkg encodes a collagen IV α2 protein. (Kimbrell, 1996.4.28) vkg is a member of the haemocyte and fat body enhancer detector strains. (Rodriguez et al., 1996)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057842 NM_001273142 NM_001273143 RefSeq (Proteins) • NP_477190 NP_001260071 NP_001260072 DDBJ / EMBL / GenBank • AAB64082 AAF52203 AC008233 AGB92607 AGB92608 AQ025683 AQ026106 AQ026115 AQ073262 BI485311 CZ473309 U65431 Entrez Gene - A searchable database of RefSeq genes. • 33726 UniProtKB/TrEMBL • O18407 Q9VMV5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Collagen IV, non-collagenous (IPR001442) Collagen triple helix repeat (IPR008160) C-type lectin fold (IPR016187) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE68619
Linkouts
	BioGRID - A database of protein and genetic interactions • 59907 DroID - A comprehensive database of gene and protein interactions. • FBgn0016075 DRSC - Results from RNAi screens. • FBgn0016075 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0016075 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG16858-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0016075 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33726 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33726 modMine - Data generated by the modENCODE project. • FBgn0016075
Synonyms & Secondary IDs ( 21 )
Reported As
Symbol Synonym	1209 (Harvie et al., 1998) 6072 (Harvie et al., 1998) CG16858 (Fakhouri et al., 2006, Quinones-Coello, 2007, Mosallanejad et al., 2010, Keleman et al., 2009.8.5, Cammarato et al., 2011) col4a2 (Kelemen-Valkony et al., 2012) coll. IV (Fakhouri et al., 2006) Coll IVα2 (Denef et al., 2008) CT25584 (Hynes and Zhao, 2000) DmColA2 (Dearolf, 1996.7.26, ) l(2)01209 (Halsell and Kiehart, 1998, ) vkg (MacMullin and Jacobs, 2006, Beller et al., 2006, Christensen and Cook, 2006.8.29, Vanderploeg et al., 2012, Buszczak et al., 2007, Quinones-Coello, 2007, Pastor-Pareja and Xu, 2011, Haigo and Bilder, 2011, Tang et al., 2008, Wang et al., 2008, Junion et al., 2007, Gilliland et al., 2009, Beebe et al., 2010, Lerner et al., 2013, Langer et al., 2010, Bunt et al., 2010, Kelemen-Valkony et al., 2012) Vkg (Akhouayri et al., 2011, Kallappagoudar et al., 2010, Alves-Silva et al., 2008, Denef et al., 2008) VkgC (Sawala et al., 2012) α(IV)2/vkg (Hynes and Zhao, 2000)
Name Synonym	collagen IV (Mirth and Akam, 2002, Kramerov and Fessler, 2000, Weavers et al., 2009, Alves-Silva et al., 2008, Guha et al., 2009, Bhave et al., 2012) Collagen IV (Stork et al., 2008, Pastor-Pareja and Xu, 2011, Urbano et al., 2009, Paddibhatla et al., 2010) collagenIV a2 (Araujo et al., 2003) collagen IV α2 (Haigo and Bilder, 2011) Type IV collagen (Yurchenco and O'Rear, 1994) type IV collagen, α-chain (Myllharju and Kivirikko, 2004) viking (Yasothornsrikul et al., 1997, Gellon et al., 1997, Rodriguez et al., 1996, Chen et al., 1996, Pastor-Pareja and Xu, 2011, Haigo and Bilder, 2011, Xie and Auld, 2011, Martinek et al., 2008, Bunt et al., 2010, Cammarato et al., 2011, Marcu et al., 2011, Bhave et al., 2012) Viking (Fakhouri et al., 2006, Momota et al., 2011, Stork et al., 2008, Beaucher et al., 2007, Wang et al., 2008, Weavers et al., 2009, Alves-Silva et al., 2008, Srivastava et al., 2007, Guha et al., 2009, Umulis et al., 2010, Bunt et al., 2011)
Secondary FlyBase IDs
	FBgn0010477
References ( 98 )
Generate a list of	All references relating to this gene ( 98 )
List References by type	Research paper  ( 58 ) Supplementary material  ( 9 ) Review  ( 6 ) Personal communication to FlyBase  ( 15 ) Abstract  ( 4 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 14 )
	Lerner et al., 2013, Dev. Cell 24(2): 159--168 A Rab10-Dependent Mechanism for Polarized Basement Membrane Secretion during Organ Morphogenesis. [FBrf0220718] Bhave et al., 2012, Nat. Chem. Biol. 8(9): 784--790 Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis. [FBrf0219311] Kelemen-Valkony et al., 2012, Matrix Biol. 31(1): 29--37 Drosophila basement membrane collagen col4a1 mutations cause severe myopathy. [FBrf0217234] Koper et al., 2012, PLoS ONE 7(4): e36339 Analysis of Adhesion Molecules and Basement Membrane Contributions to Synaptic Adhesion at the Drosophila Embryonic NMJ. [FBrf0218212] Sawala et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(28): 11222--11227 Multistep molecular mechanism for Bone morphogenetic protein extracellular transport in the Drosophila embryo. [FBrf0218813] Vanderploeg et al., 2012, BMC Dev. Biol. 12: 8 Integrins are required for cardioblast polarisation in Drosophila. [FBrf0217831] Akhouayri et al., 2011, PLoS Pathog. 7(10): e1002319 Toll-8/tollo negatively regulates antimicrobial response in the Drosophila respiratory epithelium. [FBrf0216452] Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Bunt et al., 2011, Gene Expr. Patterns 11(1-2): 72--78 Characterisation of the Drosophila procollagen lysyl hydroxylase, dPlod. [FBrf0213032] Haigo and Bilder, 2011, Science 331(6020): 1071--1074 Global tissue revolutions in a morphogenetic movement controlling elongation. [FBrf0213126] Marcu et al., 2011, PLoS ONE 6(1): e15361 Innate Immune Responses of Drosophila melanogaster Are Altered by Spaceflight. [FBrf0212851] Momota et al., 2011, Matrix Biol. 30(4): 258--266 Drosophila type XV/XVIII collagen, Mp, is involved in Wingless distribution. [FBrf0213898] Pastor-Pareja and Xu, 2011, Dev. Cell 21(2): 245--256 Shaping Cells and Organs in Drosophila by Opposing Roles of Fat Body-Secreted Collagen IV and Perlecan. [FBrf0214668] Xie and Auld, 2011, Development 138(17): 3813--3822 Integrins are necessary for the development and maintenance of the glial layers in the Drosophila peripheral nerve. [FBrf0214589] Show all research papers ...
Recent reviews ( 1 )
	Broadie et al., 2011, Dev. Neurobiol. 71(11): 1102--1130 Extracellular matrix and its receptors in drosophila neural development. [FBrf0216377] Show all reviews ...