Gene: Dmel\wun
l(2)k16806
Please see the JBrowse view of Dmel\wun for information on other features
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Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.48
1.622 (longest cDNA)
None of the polypeptides share 100% sequence identity.
300 (aa)
Homodimer. This complex seems not to be involved in substrate recognition, it may confer only structural or functional stability.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\wun using the Feature Mapper tool.
wun transcripts are first expressed at high levels in the hindgut primordium, and are expressed in a segmentally repeated pattern in the ectoderm. They are later expressed on the dorsal side of the posterior midgut. In germ band extended embryos, wun is expressed in the ectoderm in a medial band throughout the trunk. In germ band retracted embryos, wun is expressed in the gut, nervous system, and ectoderm.
GBrowse - Visual display of RNA-Seq signals
View Dmel\wun in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: wun l(2)k16806
"l(2)03497" may correspond to "wun"; the P{PZ} insertion in the "l(2)0349703497" allele maps 164bp upstream of the 5' end of the CT4876 transcript of "wun".
wun has two properties that allow it to use repulsion to guide the germ cells. wun can transform a permissive cellular environment into a repulsive one, and is expressed in the gut in a pattern that guides germ cells towards the mesoderm. Its sequence suggests that it is involved in lipid metabolism.
The wun gene is involved in guiding germ cell migration.
wun is named after a marshal in Chinese heaven, who was banished to earth in the form of a pig for causing a nuisance. Still causing a nuisance on earth, he was adopted by a monk named Tang after being outwitted in combat by the monk's monkey, Wukong. He was given the name 'Wunen', and taken on a trek to India to fetch Buddhist bark. Despite threats of further beatings, Wunen persisted in wandering off to steal food and chase beautiful girls. It is this wandering aspect of his behavior that gives the name 'wunen' to the wun gene.
