FlyBase Gene Report: Dmel\Lectin-galC1

General Information

Symbol

Dmel\Lectin-galC1

Species

D. melanogaster

Name

Galactose-specific C-type lectin

Annotation Symbol

CG9976

Feature Type

protein_coding_gene

FlyBase ID

FBgn0016675

Gene Model Status

Current

Stock Availability

3 publicly available

Gene Summary

Galactose-specific C-type lectin (Lectin-galC1) encodes a galactose binding protein involved in the induction of bacterial agglutination and cell-cell adhesion. [Date last reviewed: 2019-09-19] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

galactin, DL1

Key Links

Genomic Location

Cytogenetic map

37D6-37D6

Sequence location

2L:19,417,447..19,418,274 [+]

Recombination map

2-54

RefSeq locus

NT_033779 REGION:19417447..19418274

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (6 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables galactose binding

inferred from direct assay

(Tanji et al., 2006, Haq et al., 1996)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables carbohydrate binding

inferred from biological aspect of ancestor with PANTHER:PTN002736275

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

inferred from direct assay

(Tanji et al., 2006)

involved_in induction of bacterial agglutination

inferred from direct assay

(Tanji et al., 2006)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in extracellular region

inferred from direct assay

(Tanji et al., 2006)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in external side of plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN002736275

(assigned by GO_Central )

(Gaudet et al., 2011)

located_in extracellular region

inferred from sequence model

(Tanji et al., 2006)

Gene Group (FlyBase)

C-TYPE LECTIN-LIKE

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Galactose-specific C-type lectin (Lectin-galC1) encodes a galactose binding protein involved in the induction of bacterial agglutination and cell-cell adhesion. [Date last reviewed: 2019-09-19]

Gene Group (FlyBase)

C-TYPE LECTIN-LIKE -: C-type lectins are Ca²⁺-dependent carbohydrate-binding proteins. They possess a C-type lectin fold, that is also present in proteins that do not bind carbohydrates. (Adapted from PMID:20301263.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Lectin-galC1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure New Section

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VIX1)

If you don't see the viewer to the right, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Comments on Gene Model

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Lectin-galC1-RA

FBtr0081201

NM_057852

759

186

Lectin-galC1-RB

FBtr0302360

NM_001201916

702

186

Additional Transcript Data and Comments

Reported size (kB)

0.772 (longest cDNA)

(Haq et al., 1996)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Lectin-galC1-PA

FBpp0080742

21.5

186

6.27

NP_477200

AAF53793

Lectin-galC1-PB

FBpp0291556

21.5

186

6.27

NP_001188845

ADV37094

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

186 aa isoforms: Lectin-galC1-PA, Lectin-galC1-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

183, 163 (aa); 14 (kD observed)

(Haq et al., 1996)

Comments

The 41 kD native Lectin-galC1 protein is essentially a homotrimer of 14 kD subunits, with a glycosylated 17 kD form of the 14 kD subunit also detected by SDS-polyacrylamide gel electrophoresis. The molar ratio of the 14 kD and 17 kD subunits is estimated to be more than 2:1 , indicating that all native Lectin-galC1 trimers do not contain a glycosylated subunit. Amino-terminal sequencing of the 14 kD and 17 kD subunits indicates that they both begin at amino acid 21 of the predicted 183 amino acid polypeptide.

(Haq et al., 1996)

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Lectin-galC1 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Lectin-galC1_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage -- adult stage

organism

(Tanji et al., 2006)

third instar larval stage

(Haq et al., 1996)

pupal stage

(Haq et al., 1996)

adult stage

(Haq et al., 1996)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

organism

(Tanji et al., 2006)

testis

(Tanji et al., 2006)

adult stage | female

organism

(Tanji et al., 2006)

ovary

(Tanji et al., 2006)

adult stage

adult cuticle

(Tanji et al., 2006)

adult somatic muscle cell

(Tanji et al., 2006)

Additional Descriptive Data

Lectin-galC1 transcript is expressed from larval to adult stage, with highest expression observed in adults. Expression is higher in early pupal than in late pupal stages.

(Tanji et al., 2006)

Lectin-galC1 is detected in late third instar larvae and in early pupae; levels are low in late pupae. Expression is detected in adult flies, with significantly higher levels in males. Lectin-galC1 expression is also induced 4-6 hours after injury in second and third instar larvae.

(Haq et al., 1996)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in extracellular region

inferred from direct assay

(Tanji et al., 2006)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Lectin-galC1 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Lectin-galC1

View exonic expression by tissue for Dmel\Lectin-galC1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35216/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0016675

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0016675

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0016675

Flygut - An atlas of the Drosophila adult midgut

FBgn0016675

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Lectin-galC1

Transgenic constructs containing regulatory region of Lectin-galC1

Aberrations (Deficiencies and Duplications) ( 3 )

Inferred from experimentation ( 3 )

Gene disrupted in

Df(2L)E136

(Tanji et al., 2006)

Df(2L)Exel6043

(Ryder, 2004.4.26)

Df(2L)Exel7075

(Ryder, 2004.4.26)

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Scer\GAL4^Mef2.PR

Lectin-galC1^GD5331

viable, with Scer\GAL4^pnr-MD237

Lectin-galC1^GD5331

viable, with Scer\GAL4^tin.CΔ4

Lectin-galC1^GD5331

Other Phenotypes

Allele

abnormal locomotor behavior | wandering third instar larval stage

Lectin-galC1^fs

abnormal locomotor behavior | wandering third instar larval stage (with Df(2L)Exel6043)

Lectin-galC1^fs

abnormal neurophysiology | wandering third instar larval stage

Lectin-galC1^fs

abnormal neurophysiology | wandering third instar larval stage (with Df(2L)Exel6043)

Lectin-galC1^fs

abnormal neurophysiology | wandering third instar larval stage | conditional

Lectin-galC1^fs

abnormal neurophysiology | wandering third instar larval stage | conditional (with Df(2L)Exel6043)

Lectin-galC1^fs

Phenotype manifest in

Allele

embryonic/larval neuromuscular junction | wandering third instar larval stage

Lectin-galC1^fs

embryonic/larval neuromuscular junction | wandering third instar larval stage (with Df(2L)Exel6043)

Lectin-galC1^fs

NMJ bouton | wandering third instar larval stage

Lectin-galC1^fs

NMJ bouton | wandering third instar larval stage (with Df(2L)Exel6043)

Lectin-galC1^fs

synapse | increased number | wandering third instar larval stage

Lectin-galC1^fs

synapse | increased number | wandering third instar larval stage (with Df(2L)Exel6043)

Lectin-galC1^fs

synaptic vesicle | decreased number | wandering third instar larval stage

Lectin-galC1^fs

synaptic vesicle | decreased number | wandering third instar larval stage (with Df(2L)Exel6043)

Lectin-galC1^fs

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (24)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\CLEC4D

3 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (36)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Cd209a

2 of 15

Yes

Mmus\Cd209b

2 of 15

Yes

Mmus\Cd209c

2 of 15

Yes

Mmus\Cd209e

2 of 15

Yes

Mmus\Clec4e

2 of 15

Yes

Mmus\Clec4g

2 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Mmus\Clec10a

1 of 15

Mmus\Clec12b

1 of 15

Yes

Mmus\Fcer2a

1 of 15

Mmus\Gm156

1 of 15

Mmus\Gm32766

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Mmus\Sftpd

1 of 15

Rattus norvegicus (Norway rat) (35)

Rnor\Asgr1

2 of 13

Yes

Rnor\Cd209e

2 of 13

Yes

Rnor\LOC100363064

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Rnor\Colec10

1 of 13

Rnor\Fcer2

1 of 13

Rnor\Klrh1

1 of 13

Yes

Rnor\LOC688858

1 of 13

Yes

Rnor\LOC690097

1 of 13

Yes

Rnor\LOC100363914

1 of 13

Yes

Rnor\LOC100911529

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Rnor\Sftpd

1 of 13

Xenopus tropicalis (Western clawed frog) (9)

Xtro\clec4e

1 of 12

Yes

Xtro\clec19a

1 of 12

Yes

Xtro\LOC100486944

1 of 12

Yes

Xtro\LOC100487836

1 of 12

Yes

Xtro\LOC100494969

1 of 12

Yes

Xtro\LOC101734545

1 of 12

Yes

Xtro\LOC101735054

1 of 12

Yes

Xtro\reg1b

1 of 12

Yes

Xtro\reg4

1 of 12

Yes

Danio rerio (Zebrafish) (70)

Drer\zmp:0000000937

3 of 15

Yes

Drer\cd209

2 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

Yes

Drer\si:ch73-86n18.1

2 of 15

Drer\si:ch73-111e15.1

2 of 15

Yes

Drer\si:ch73-122g19.1

2 of 15

Drer\si:ch73-343l4.2

2 of 15

Drer\si:ch73-343l4.8

2 of 15

Drer\si:ch211-214k5.3

2 of 15

Drer\si:ch211-232p21.6

2 of 15

Drer\si:dkey-187i8.2

2 of 15

Drer\zmp:0000000924

2 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Drer\LOC100537143

1 of 15

Yes

Drer\LOC100537194

1 of 15

Yes

Drer\LOC100537240

1 of 15

Yes

Drer\LOC101882781

1 of 15

Yes

Drer\LOC101884413

1 of 15

Drer\LOC101885796

1 of 15

Yes

Drer\LOC101886459

1 of 15

Yes

Drer\LOC101886537

1 of 15

Drer\LOC103910168

1 of 15

Drer\LOC103911722

1 of 15

Yes

Drer\LOC108179137

1 of 15

Yes

Drer\LOC110438235

1 of 15

Yes

Drer\LOC110438236

1 of 15

Yes

Drer\LOC110438686

1 of 15

Yes

Drer\LOC110438783

1 of 15

Yes

Drer\LOC110438854

1 of 15

Yes

Drer\LOC110440085

1 of 15

Drer\selp

1 of 15

Drer\si:busm1-169i8.11

1 of 15

Yes

Drer\si:ch211-125e6.5

1 of 15

Drer\si:ch211-125e6.11

1 of 15

Drer\si:ch211-125e6.14

1 of 15

Drer\si:ch211-133n4.7

1 of 15

Drer\si:ch211-160b11.4

1 of 15

Drer\si:ch211-193e13.5

1 of 15

Yes

Drer\si:ch211-225k7.6

1 of 15

Yes

Drer\si:ch211-282j17.3

1 of 15

Yes

Drer\si:ch211-283g2.2

1 of 15

Yes

Drer\si:ch211-283g2.3

1 of 15

Drer\si:dkey-9i23.4

1 of 15

Drer\si:dkey-9i23.5

1 of 15

Drer\si:dkey-26c10.5

1 of 15

Yes

Drer\si:dkey-28d5.7

1 of 15

Yes

Drer\si:dkey-61f9.1

1 of 15

Drer\si:dkey-61f9.2

1 of 15

Drer\si:dkey-83f18.10

1 of 15

Yes

Drer\si:dkey-88n24.6

1 of 15

Yes

Drer\si:dkey-88n24.7

1 of 15

Yes

Drer\si:dkey-88n24.10

1 of 15

Yes

Drer\si:dkey-241l7.3

1 of 15

Drer\si:dkey-241l7.4

1 of 15

Drer\si:dkey-241l7.6

1 of 15

Drer\si:dkeyp-75b4.10

1 of 15

Drer\vcana

1 of 15

Yes

Drer\zgc:172053

1 of 15

Drer\zgc:174904

1 of 15

Drer\zgc:194252

1 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (67)

Cele\clec-4

2 of 15

Yes

Cele\clec-7

2 of 15

Yes

Cele\clec-26

2 of 15

Yes

Cele\clec-28

2 of 15

Yes

Cele\clec-39

2 of 15

Yes

Cele\clec-45

2 of 15

Yes

Cele\clec-149

2 of 15

Yes

Cele\C25G4.17

1 of 15

Yes

Cele\C49C3.11

1 of 15

Yes

Cele\clec-9

1 of 15

Yes

Cele\clec-17

1 of 15

Yes

Cele\clec-21

1 of 15

Yes

Cele\clec-24

1 of 15

Yes

Cele\clec-31

1 of 15

Yes

Cele\clec-32

1 of 15

Yes

Cele\clec-34

1 of 15

Yes

Cele\clec-38

1 of 15

Yes

Cele\clec-44

1 of 15

Yes

Cele\clec-50

1 of 15

Cele\clec-73

1 of 15

Yes

Cele\clec-79

1 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Yes

Cele\clec-96

1 of 15

Yes

Cele\clec-99

1 of 15

Yes

Cele\clec-108

1 of 15

Yes

Cele\clec-109

1 of 15

Yes

Cele\clec-111

1 of 15

Yes

Cele\clec-113

1 of 15

Yes

Cele\clec-117

1 of 15

Yes

Cele\clec-118

1 of 15

Yes

Cele\clec-121

1 of 15

Yes

Cele\clec-123

1 of 15

Yes

Cele\clec-124

1 of 15

Yes

Cele\clec-127

1 of 15

Yes

Cele\clec-129

1 of 15

Yes

Cele\clec-133

1 of 15

Yes

Cele\clec-144

1 of 15

Yes

Cele\clec-148

1 of 15

Cele\clec-150

1 of 15

Yes

Cele\clec-151

1 of 15

Yes

Cele\clec-156

1 of 15

Yes

Cele\clec-181

1 of 15

Yes

Cele\clec-183

1 of 15

Yes

Cele\clec-184

1 of 15

Yes

Cele\clec-185

1 of 15

Yes

Cele\clec-191

1 of 15

Yes

Cele\clec-195

1 of 15

Yes

Cele\clec-197

1 of 15

Yes

Cele\clec-198

1 of 15

Cele\clec-199

1 of 15

Yes

Cele\clec-203

1 of 15

Yes

Cele\clec-208

1 of 15

Yes

Cele\clec-224

1 of 15

Yes

Cele\clec-225

1 of 15

Yes

Cele\clec-226

1 of 15

Yes

Cele\clec-238

1 of 15

Yes

Cele\clec-242

1 of 15

Yes

Cele\clec-260

1 of 15

Yes

Cele\clec-262

1 of 15

Yes

Cele\clec-266

1 of 15

Cele\T07H3.10

1 of 15

Yes

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Other Organism Orthologs (via OrthoDB)

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (28)

Gene Symbol

Score

Source

Alignment

5 of 10

5 of 10

3 of 10

3 of 10

3 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

tfc

2 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CLEC4D; C-type lectin domain family 4 member D

3 of 15

609964

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

61196

DroID - A comprehensive database of gene and protein interactions.

FBgn0016675

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0016675

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-54

Cytogenetic map

37D6-37D6

Sequence location

2L:19,417,447..19,418,274 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

37D6-37D6

Limits computationally determined from genome sequence between P{EP}dnt^EP2158 and P{EP}EP623&P{PZ}spi⁰¹⁰⁶⁸

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

37B-37B

(determined by in situ hybridisation)

(Haq et al., 1996)

Experimentally Determined Recombination Data

Location

2-54

(FlyBase, 2016)

2-53.7

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (3)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

57001

y¹ sc^* v¹ sev²¹; P{TRiP.HMC04443}attP40

VDRC

v100935

P{KK106280}VIE-260B

v38001

w¹¹¹⁸; P{GD5331}v38001

Genomic Clones (15)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (8)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

IP02782

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0016675

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0016675

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35216

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Bhimreddy et al., 2021)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Lectin-galC1 CG9976

(Theopold, 2000.7.21)

Source for database merge of

Additional comments

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 34 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35216

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VIX1

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VIX1

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0016675

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35216/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0016675

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Lectin-galC1_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0016675

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0016675

Flygut - An atlas of the Drosophila adult midgut

FBgn0016675

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0016675

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35216

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG9976

MARRVEL_MODEL - MARRVEL (model organism gene)

35216

modMine - A data warehouse for the modENCODE project

FBgn0016675

Linkouts

BioGRID - A database of protein and genetic interactions.

61196

DroID - A comprehensive database of gene and protein interactions.

FBgn0016675

DRSC - Results frm RNAi screens

FBgn0016675

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0016675

FlyMine - An integrated database for Drosophila genomics

FBgn0016675

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

AC007082a

(Theopold, 2000.7.21)

CG9976

(Lu et al., 2020, Herranz et al., 2012, Ni et al., 2010.12.1, Zhang et al., 2010, Keleman et al., 2009.8.5)

DL1

(Lu et al., 2020, Tanji et al., 2006)

Dgal-1

(Theopold et al., 1999)

LGC1

(Bhimreddy et al., 2021)

Lecti-galC1

(Levine et al., 2011)

Lectin-galC1

(Christesen et al., 2017, Seong et al., 2017, Paparazzo et al., 2015, Brown et al., 2014, Keebaugh and Schlenke, 2014, Marcu et al., 2011)

lectin-galC1

(Sharma et al., 2011)

Name Synonyms

Drosophila lectin 1

(Tanji et al., 2006)

Galactose-specific C-type lectin

(Marcu et al., 2011, Harbison et al., 2005)

Lectin-galC1

(Rushton et al., 2020)

galactin

(Kimbrell and Beutler, 2001, Khush and Lemaitre, 2000)

galactose specific C-type lectin