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Gene Mdoa\Hermes\T

General Information
Symbol	Mdoa\Hermes\T	Species	M. domestica
Name	Hermes transposase	Annotation symbol
Feature type	engineered_foreign_gene	FlyBase ID	FBgn0016681
Gene Model Status	Not Applicable	Stock availability	None publicly available
Genomic Location
Chromosome (arm)		Recombination map
Cytogenetic map		Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene Hermes transposase is referred to in FlyBase by the symbol Mdoa\Hermes\T (FBgn0016681). It is a engineered_foreign_gene from Musca domestica. It is encoded by the Mdoa\Hermes transposable element. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has no annotated transcripts. Gene has not been localized to the genome sequence.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Mdoa\Hermes\T Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Mdoa\Hermes\T Class Mutagen Stocks Known lesion Mdoa\Hermes\TD402N.hs in vitro construct - amino acid replacement 0 Yes Mdoa\Hermes\TDpse\Hsp83.PS in vitro construct - regulatory fusion 0 Yes Mdoa\Hermes\TE572Q.hs in vitro construct - amino acid replacement 0 Yes Mdoa\Hermes\Ths.PO in vitro construct - regulatory fusion 0 Yes Mdoa\Hermes\Ths.PS in vitro construct - regulatory fusion 0 Yes Mdoa\Hermes\TRL in vitro construct 0 Yes Mdoa\Hermes\TS535A.hs in vitro construct - amino acid replacement 0 Yes Mdoa\Hermes\TS535D.hs in vitro construct - amino acid replacement 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	engineered_foreign_gene   transposable_element_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Mdoa\Hermes\T allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Ortholog(s) in Drosophila melanogaster (None identified)
No D. melanogaster orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Encoded by	Mdoa\Hermes
Additional comments
Other Comments
	Constructs based on Mdoa\Hermes can act as a functional non-Drosophilid vector in germline transformation. The frequency of transformation is comparable to that reported for hobo or P-element based vectors. (O'Brochta et al., 1996)
Tag or Foreign Gene Data
	Foreign sequence; species == Musca domestica; gene == 'Hermes transposase'.
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Mdoa\Hermes\T
Name Synonym	Hermes transposase (O'Brochta et al., 1996, Michel and Atkinson, 2003)
Secondary FlyBase IDs
References ( 9 )
Research paper	O'Brochta et al., 2009, BMC Mol. Biol. 10: 108 Transpositionally active episomal hAT elements. [FBrf0209679] Horn et al., 2003, Genetics 163(2): 647--661 piggyBac-based insertional mutagenesis and enhancer detection as a tool for functional insect genomics. [FBrf0158985] Michel and Atkinson, 2003, J. Cell. Biochem. 89(4): 778--790 Nuclear localization of the Hermes transposase depends on basic amino acid residues at the N-terminus of the protein. [FBrf0160794] Michel et al., 2002, Gene 298(2): 141--146 Does the proposed DSE motif form the active center in the Hermes transposase? [FBrf0155779] Horn and Wimmer, 2000, Dev. Genes Evol. 210(12): 630--637 A versatile vector set for animal transgenesis. [FBrf0134553] Sundararajan et al., 1999, Insect Mol. Biol. 8(3): 359--368 Transposable element interactions in insects: crossmobilization of hobo and Hermes. [FBrf0111498] Sarkar et al., 1997, Genetica 99(1): 15--29 The Hermes element from Musca domestica can transpose in four families of cyclorrhaphan flies. [FBrf0096232] O'Brochta et al., 1996, Genetics 142(3): 907--914 Hermes, a functional non-drosophilid insect gene vector from Musca domestica. [FBrf0086560]
FlyBase analysis	FlyBase Curators, 1992-, Summary information describing the origin of tags and foreign genes in FlyBase. Summary information describing the origin of tags and foreign genes in FlyBase. [FBrf0199194]