Gene Dmel\Nurf-38

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General Information

Symbol

Dmel\Nurf-38

Species

D. melanogaster

Name

Nucleosome remodeling factor - 38kD

Annotation symbol

CG4634

Feature type

protein_coding_gene

FlyBase ID

FBgn0016687

Gene Model Status

Current

Stock availability

6 publicly available

Also Known As

NURF, Nurf38, dNURF, p38, l(2)k16102

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

60D5-60D5

Sequence location

2R:20,446,490..20,448,610 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene Nucleosome remodeling factor - 38kD is referred to in FlyBase by the symbol Dmel\Nurf-38 (CG4634, FBgn0016687). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: inorganic diphosphatase activity. There is experimental evidence that it is involved in the biological process: ecdysone receptor-mediated signaling pathway; transcription, DNA-dependent; nucleosome mobilization; positive regulation of Notch signaling pathway; regulation of hemocyte proliferation; chromatin remodeling. 7 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Inorganic pyrophosphatase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval Malpighian tubules, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1637982_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Nurf-38. Gene sequence location is 2R:20446490..20448610.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

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This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

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Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

60D5-60D5

Limits computationally determined from genome sequence between P{PZ}bs⁰³²⁶⁷&P{lacW}l(2)k10502^k10502 and P{lacW}Nurf-38^k16102

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

60C-60C

(Gdula, 1998.8.20)

60C-60C

(Gdula, 1998.8.20)

60D5-60D6

(determined by in situ hybridisation)

(Spradling et al., 1999)

60C-60C

(Gdula et al., 1998)

60D5-60D6

(Beaton, 1997.12.27)

60D5-60D6

(BDGP Project Members, 1994-1999)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\Nurf-38 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Nurf-38-RA

FBtr0072343

NM_079125

1178

338

Nurf-38-RB

FBtr0273253

NM_001144286

1143

290

Nurf-38-RC

FBtr0305985

NM_001259565

1273

290

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Nurf-38-PA

FBpp0072250

37.9

338

7.01

NP_523849

AAF47227

Nurf-38-PB

FBpp0271761

32.6

290

5.41

NP_001137758

ACL83211

Nurf-38-PC

FBpp0297127

32.5

290

5.66

NP_001246494

AFH08247

Additional Polypeptide Data & Comments

Reported size (kDa)

290 (aa); 40 (kD observed); 33 (kD predicted)

(Gdula et al., 1998)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Inorganic pyrophosphatase (IPR008162)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

O77460

UniProtKB/TrEMBL

B7YZQ7

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Wasbrough et al., 2010)

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Nurf-38 protein is observed in both the cytoplasm and the nucleus.

(Gdula et al., 1998)

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

cytoplasm

inferred from direct assay

(Gdula et al., 1998)

nucleus

inferred from direct assay

(Gdula et al., 1998)

NURF complex

inferred from direct assay AND inferred from physical interaction with Caf1 AND inferred from physical interaction with Iswi

(Gdula et al., 1998)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval Malpighian tubules, adult testis.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1078.8
Larval Midgut		1514.8
Larval Hindgut		1213.9
Larval Malpighian Tubules		478.6
Larval Fat Body		812.6
Larval Salivary Gland		1993
Larval Trachea		1406.05
Larval Carcass		956.8
Adult Head		1330
Adult Eye		1115.5
Adult Brain		658.5
Adult Thoracic-Abdominal Ganglion		700.5
Adult Crop		1223.7
Adult Midgut		1447.1
Adult Hindgut		1161.6
Adult Malpighian Tubules		1253.2
Adult Fat Body		2232.3
Adult Salivary Gland		1682.3
Adult Heart		2170.225
Adult VirginFemale Spermatheca		2105
Adult InseminatedFemale Spermatheca		1895.4
Adult Ovary		1071.5
Adult Testis		303.7
Adult Male Accessory Gland		1384.7
Adult Carcass		2036.7
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1078.8)
Larval Midgut		(1514.8)
Larval Hindgut		(1213.9)
Larval Malpighian Tubules		478.6
Larval Fat Body		(812.6)
Larval Salivary Gland		(1993)
Larval Trachea		(1406.05)
Larval Carcass		(956.8)
Adult Head		(1330)
Adult Eye		(1115.5)
Adult Brain		(658.5)
Adult Thoracic-Abdominal Ganglion		(700.5)
Adult Crop		(1223.7)
Adult Midgut		(1447.1)
Adult Hindgut		(1161.6)
Adult Malpighian Tubules		(1253.2)
Adult Fat Body		(2232.3)
Adult Salivary Gland		(1682.3)
Adult Heart		(2170.225)
Adult VirginFemale Spermatheca		(2105)
Adult InseminatedFemale Spermatheca		(1895.4)
Adult Ovary		(1071.5)
Adult Testis		303.7
Adult Male Accessory Gland		(1384.7)
Adult Carcass		(2036.7)
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		(1078.8)
Larval Midgut		(1514.8)
Larval Hindgut		(1213.9)
Larval Malpighian Tubules		478.6
Larval Fat Body		812.6
Larval Salivary Gland		(1993)
Larval Trachea		(1406.05)
Larval Carcass		956.8
Adult Head		(1330)
Adult Eye		(1115.5)
Adult Brain		658.5
Adult Thoracic-Abdominal Ganglion		700.5
Adult Crop		(1223.7)
Adult Midgut		(1447.1)
Adult Hindgut		(1161.6)
Adult Malpighian Tubules		(1253.2)
Adult Fat Body		(2232.3)
Adult Salivary Gland		(1682.3)
Adult Heart		(2170.225)
Adult VirginFemale Spermatheca		(2105)
Adult InseminatedFemale Spermatheca		(1895.4)
Adult Ovary		1071.5
Adult Testis		303.7
Adult Male Accessory Gland		(1384.7)
Adult Carcass		(2036.7)
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1078.8
Larval Midgut		1514.8
Larval Hindgut		1213.9
Larval Malpighian Tubules		478.6
Larval Fat Body		812.6
Larval Salivary Gland		1993
Larval Trachea		1406.05
Larval Carcass		956.8
Adult Head		1330
Adult Eye		1115.5
Adult Brain		658.5
Adult Thoracic-Abdominal Ganglion		700.5
Adult Crop		1223.7
Adult Midgut		1447.1
Adult Hindgut		1161.6
Adult Malpighian Tubules		1253.2
Adult Fat Body		2232.3
Adult Salivary Gland		1682.3
Adult Heart		2170.225
Adult VirginFemale Spermatheca		2105
Adult InseminatedFemale Spermatheca		1895.4
Adult Ovary		1071.5
Adult Testis		303.7
Adult Male Accessory Gland		1384.7
Adult Carcass		2036.7
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1078.8
Larval Midgut		1514.8
Larval Hindgut		1213.9
Larval Malpighian Tubules		478.6
Larval Fat Body		812.6
Larval Salivary Gland		1993
Larval Trachea		1406.05
Larval Carcass		956.8
Adult Head		1330
Adult Eye		1115.5
Adult Brain		658.5
Adult Thoracic-Abdominal Ganglion		700.5
Adult Crop		1223.7
Adult Midgut		1447.1
Adult Hindgut		1161.6
Adult Malpighian Tubules		1253.2
Adult Fat Body		2232.3
Adult Salivary Gland		1682.3
Adult Heart		2170.225
Adult VirginFemale Spermatheca		2105
Adult InseminatedFemale Spermatheca		1895.4
Adult Ovary		1071.5
Adult Testis		303.7
Adult Male Accessory Gland		1384.7
Adult Carcass		2036.7
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1078.8)
Larval Midgut		(1514.8)
Larval Hindgut		(1213.9)
Larval Malpighian Tubules		478.6
Larval Fat Body		812.6
Larval Salivary Gland		(1993)
Larval Trachea		(1406.05)
Larval Carcass		(956.8)
Adult Head		(1330)
Adult Eye		(1115.5)
Adult Brain		658.5
Adult Thoracic-Abdominal Ganglion		700.5
Adult Crop		(1223.7)
Adult Midgut		(1447.1)
Adult Hindgut		(1161.6)
Adult Malpighian Tubules		(1253.2)
Adult Fat Body		(2232.3)
Adult Salivary Gland		(1682.3)
Adult Heart		(2170.225)
Adult VirginFemale Spermatheca		(2105)
Adult InseminatedFemale Spermatheca		(1895.4)
Adult Ovary		(1071.5)
Adult Testis		303.7
Adult Male Accessory Gland		(1384.7)
Adult Carcass		(2036.7)
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1078.8
Larval Midgut		1514.8
Larval Hindgut		1213.9
Larval Malpighian Tubules		478.6
Larval Fat Body		812.6
Larval Salivary Gland		(1993)
Larval Trachea		1406.05
Larval Carcass		956.8
Adult Head		1330
Adult Eye		1115.5
Adult Brain		658.5
Adult Thoracic-Abdominal Ganglion		700.5
Adult Crop		1223.7
Adult Midgut		1447.1
Adult Hindgut		1161.6
Adult Malpighian Tubules		1253.2
Adult Fat Body		(2232.3)
Adult Salivary Gland		1682.3
Adult Heart		(2170.225)
Adult VirginFemale Spermatheca		(2105)
Adult InseminatedFemale Spermatheca		(1895.4)
Adult Ovary		1071.5
Adult Testis		303.7
Adult Male Accessory Gland		1384.7
Adult Carcass		(2036.7)
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1078.8
Larval Midgut		1514.8
Larval Hindgut		1213.9
Larval Malpighian Tubules		478.6
Larval Fat Body		812.6
Larval Salivary Gland		1993
Larval Trachea		1406.05
Larval Carcass		956.8
Adult Head		1330
Adult Eye		1115.5
Adult Brain		658.5
Adult Thoracic-Abdominal Ganglion		700.5
Adult Crop		1223.7
Adult Midgut		1447.1
Adult Hindgut		1161.6
Adult Malpighian Tubules		1253.2
Adult Fat Body		2232.3
Adult Salivary Gland		1682.3
Adult Heart		2170.225
Adult VirginFemale Spermatheca		2105
Adult InseminatedFemale Spermatheca		1895.4
Adult Ovary		1071.5
Adult Testis		303.7
Adult Male Accessory Gland		1384.7
Adult Carcass		2036.7
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	1330
NA	Eye	1115.5
NA	Brain	658.5
1078.8	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	700.5
NA	Crop	1223.7
1514.8	Midgut	1447.1
1213.9	Hindgut	1161.6
478.6	Malpighian Tubules	1253.2
812.6	Fat Body	2232.3
1993	Salivary Gland	1682.3
NA	Heart	2170.225
1406.05	Trachea	NA
NA	VirginFemale Spermatheca	2105
NA	InseminatedFemale Spermatheca	1895.4
NA	Ovary	1071.5
NA	Testis	303.7
NA	Male Accessory Gland	1384.7
956.8	Carcass	2036.7

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		144
central nervous system, larvae L3		106
central nervous system, pupae P8		48
head, virgin 1-day female		130
head, virgin 4-day female		89
head, virgin 20-day female		144
head, mated 1-day female		75
head, mated 4-day female		85
head, mated 20-day female		127
head, mated 1-day male		85
head, mated 4-day male		126
head, mated 20-day male		233
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		31
digestive system, larvae L3 wandering		59
digestive system, 1-day adult		123
digestive system, 4-day adult		90
digestive system, 20-day adult		87
fat body, larvae L3 wandering		32
fat body, white prepupae		62
fat body, pupae P8		55
carcass, larvae L3 wandering		97
carcass, 1-day adult		116
carcass, 4-day adult		133
carcass, 20-day adult		194
ovary, virgin 4-day female		155
ovary, mated 4-day female		133
testis, mated 4-day male		91
accessory gland, mated 4-day male		82
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(144)
central nervous system, larvae L3		(106)
central nervous system, pupae P8		(48)
head, virgin 1-day female		(130)
head, virgin 4-day female		(89)
head, virgin 20-day female		(144)
head, mated 1-day female		(75)
head, mated 4-day female		(85)
head, mated 20-day female		(127)
head, mated 1-day male		(85)
head, mated 4-day male		(126)
head, mated 20-day male		(233)
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		(31)
digestive system, larvae L3 wandering		(59)
digestive system, 1-day adult		(123)
digestive system, 4-day adult		(90)
digestive system, 20-day adult		(87)
fat body, larvae L3 wandering		(32)
fat body, white prepupae		(62)
fat body, pupae P8		(55)
carcass, larvae L3 wandering		(97)
carcass, 1-day adult		(116)
carcass, 4-day adult		(133)
carcass, 20-day adult		(194)
ovary, virgin 4-day female		(155)
ovary, mated 4-day female		(133)
testis, mated 4-day male		(91)
accessory gland, mated 4-day male		(82)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(144)
central nervous system, larvae L3		106
central nervous system, pupae P8		48
head, virgin 1-day female		(130)
head, virgin 4-day female		89
head, virgin 20-day female		(144)
head, mated 1-day female		75
head, mated 4-day female		85
head, mated 20-day female		(127)
head, mated 1-day male		85
head, mated 4-day male		(126)
head, mated 20-day male		(233)
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		31
digestive system, larvae L3 wandering		59
digestive system, 1-day adult		(123)
digestive system, 4-day adult		90
digestive system, 20-day adult		87
fat body, larvae L3 wandering		32
fat body, white prepupae		62
fat body, pupae P8		55
carcass, larvae L3 wandering		97
carcass, 1-day adult		(116)
carcass, 4-day adult		(133)
carcass, 20-day adult		(194)
ovary, virgin 4-day female		(155)
ovary, mated 4-day female		(133)
testis, mated 4-day male		91
accessory gland, mated 4-day male		82
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		144
central nervous system, larvae L3		106
central nervous system, pupae P8		48
head, virgin 1-day female		130
head, virgin 4-day female		89
head, virgin 20-day female		144
head, mated 1-day female		75
head, mated 4-day female		85
head, mated 20-day female		127
head, mated 1-day male		85
head, mated 4-day male		126
head, mated 20-day male		233
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		31
digestive system, larvae L3 wandering		59
digestive system, 1-day adult		123
digestive system, 4-day adult		90
digestive system, 20-day adult		87
fat body, larvae L3 wandering		32
fat body, white prepupae		62
fat body, pupae P8		55
carcass, larvae L3 wandering		97
carcass, 1-day adult		116
carcass, 4-day adult		133
carcass, 20-day adult		194
ovary, virgin 4-day female		155
ovary, mated 4-day female		133
testis, mated 4-day male		91
accessory gland, mated 4-day male		82
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		144
central nervous system, larvae L3		106
central nervous system, pupae P8		48
head, virgin 1-day female		130
head, virgin 4-day female		89
head, virgin 20-day female		144
head, mated 1-day female		75
head, mated 4-day female		85
head, mated 20-day female		127
head, mated 1-day male		85
head, mated 4-day male		126
head, mated 20-day male		233
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		31
digestive system, larvae L3 wandering		59
digestive system, 1-day adult		123
digestive system, 4-day adult		90
digestive system, 20-day adult		87
fat body, larvae L3 wandering		32
fat body, white prepupae		62
fat body, pupae P8		55
carcass, larvae L3 wandering		97
carcass, 1-day adult		116
carcass, 4-day adult		133
carcass, 20-day adult		194
ovary, virgin 4-day female		155
ovary, mated 4-day female		133
testis, mated 4-day male		91
accessory gland, mated 4-day male		82
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(144)
central nervous system, larvae L3		(106)
central nervous system, pupae P8		(48)
head, virgin 1-day female		(130)
head, virgin 4-day female		(89)
head, virgin 20-day female		(144)
head, mated 1-day female		(75)
head, mated 4-day female		(85)
head, mated 20-day female		(127)
head, mated 1-day male		(85)
head, mated 4-day male		(126)
head, mated 20-day male		(233)
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		31
digestive system, larvae L3 wandering		(59)
digestive system, 1-day adult		(123)
digestive system, 4-day adult		(90)
digestive system, 20-day adult		(87)
fat body, larvae L3 wandering		32
fat body, white prepupae		(62)
fat body, pupae P8		(55)
carcass, larvae L3 wandering		(97)
carcass, 1-day adult		(116)
carcass, 4-day adult		(133)
carcass, 20-day adult		(194)
ovary, virgin 4-day female		(155)
ovary, mated 4-day female		(133)
testis, mated 4-day male		(91)
accessory gland, mated 4-day male		(82)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(144)
central nervous system, larvae L3		106
central nervous system, pupae P8		48
head, virgin 1-day female		130
head, virgin 4-day female		89
head, virgin 20-day female		(144)
head, mated 1-day female		75
head, mated 4-day female		85
head, mated 20-day female		127
head, mated 1-day male		85
head, mated 4-day male		126
head, mated 20-day male		(233)
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		31
digestive system, larvae L3 wandering		59
digestive system, 1-day adult		123
digestive system, 4-day adult		90
digestive system, 20-day adult		87
fat body, larvae L3 wandering		32
fat body, white prepupae		62
fat body, pupae P8		55
carcass, larvae L3 wandering		97
carcass, 1-day adult		116
carcass, 4-day adult		133
carcass, 20-day adult		(194)
ovary, virgin 4-day female		(155)
ovary, mated 4-day female		133
testis, mated 4-day male		91
accessory gland, mated 4-day male		82
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		144
central nervous system, larvae L3		106
central nervous system, pupae P8		48
head, virgin 1-day female		130
head, virgin 4-day female		89
head, virgin 20-day female		144
head, mated 1-day female		75
head, mated 4-day female		85
head, mated 20-day female		127
head, mated 1-day male		85
head, mated 4-day male		126
head, mated 20-day male		233
salivary gland, larvae L3 wandering		21
salivary gland, white prepupae		31
digestive system, larvae L3 wandering		59
digestive system, 1-day adult		123
digestive system, 4-day adult		90
digestive system, 20-day adult		87
fat body, larvae L3 wandering		32
fat body, white prepupae		62
fat body, pupae P8		55
carcass, larvae L3 wandering		97
carcass, 1-day adult		116
carcass, 4-day adult		133
carcass, 20-day adult		194
ovary, virgin 4-day female		155
ovary, mated 4-day female		133
testis, mated 4-day male		91
accessory gland, mated 4-day male		82
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in stages of adults of both sexes.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		177
embryo 02-04hr		59
embryo 04-06hr		87
embryo 06-08hr		90
embryo 08-10hr		91
embryo 10-12hr		123
embryo 12-14hr		72
embryo 14-16hr		78
embryo 16-18hr		84
embryo 18-20hr		93
embryo 20-22hr		130
embryo 22-24hr		127
larva L1		228
larva L2		260
larva L3 12hr old		238
larva L3 puffstage 1-2		100
larva L3 puffstage 3-6		80
larva L3 puffstage 7-9		85
white prepupae new		83
white prepupae 12hr		70
white prepupae 24hr		81
pupae 2d postWPP		75
pupae 3d postWPP		71
pupae 4d postWPP		79
adult male 01day		131
adult male 05day		132
adult male 30day		121
adult female 01day		190
adult female 05day		206
adult female 30day		201
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(177)
embryo 02-04hr		(59)
embryo 04-06hr		(87)
embryo 06-08hr		(90)
embryo 08-10hr		(91)
embryo 10-12hr		(123)
embryo 12-14hr		(72)
embryo 14-16hr		(78)
embryo 16-18hr		(84)
embryo 18-20hr		(93)
embryo 20-22hr		(130)
embryo 22-24hr		(127)
larva L1		(228)
larva L2		(260)
larva L3 12hr old		(238)
larva L3 puffstage 1-2		(100)
larva L3 puffstage 3-6		(80)
larva L3 puffstage 7-9		(85)
white prepupae new		(83)
white prepupae 12hr		(70)
white prepupae 24hr		(81)
pupae 2d postWPP		(75)
pupae 3d postWPP		(71)
pupae 4d postWPP		(79)
adult male 01day		(131)
adult male 05day		(132)
adult male 30day		(121)
adult female 01day		(190)
adult female 05day		(206)
adult female 30day		(201)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(177)
embryo 02-04hr		59
embryo 04-06hr		87
embryo 06-08hr		90
embryo 08-10hr		91
embryo 10-12hr		(123)
embryo 12-14hr		72
embryo 14-16hr		78
embryo 16-18hr		84
embryo 18-20hr		93
embryo 20-22hr		(130)
embryo 22-24hr		(127)
larva L1		(228)
larva L2		(260)
larva L3 12hr old		(238)
larva L3 puffstage 1-2		100
larva L3 puffstage 3-6		80
larva L3 puffstage 7-9		85
white prepupae new		83
white prepupae 12hr		70
white prepupae 24hr		81
pupae 2d postWPP		75
pupae 3d postWPP		71
pupae 4d postWPP		79
adult male 01day		(131)
adult male 05day		(132)
adult male 30day		(121)
adult female 01day		(190)
adult female 05day		(206)
adult female 30day		(201)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		177
embryo 02-04hr		59
embryo 04-06hr		87
embryo 06-08hr		90
embryo 08-10hr		91
embryo 10-12hr		123
embryo 12-14hr		72
embryo 14-16hr		78
embryo 16-18hr		84
embryo 18-20hr		93
embryo 20-22hr		130
embryo 22-24hr		127
larva L1		228
larva L2		260
larva L3 12hr old		238
larva L3 puffstage 1-2		100
larva L3 puffstage 3-6		80
larva L3 puffstage 7-9		85
white prepupae new		83
white prepupae 12hr		70
white prepupae 24hr		81
pupae 2d postWPP		75
pupae 3d postWPP		71
pupae 4d postWPP		79
adult male 01day		131
adult male 05day		132
adult male 30day		121
adult female 01day		190
adult female 05day		206
adult female 30day		201
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		177
embryo 02-04hr		59
embryo 04-06hr		87
embryo 06-08hr		90
embryo 08-10hr		91
embryo 10-12hr		123
embryo 12-14hr		72
embryo 14-16hr		78
embryo 16-18hr		84
embryo 18-20hr		93
embryo 20-22hr		130
embryo 22-24hr		127
larva L1		228
larva L2		260
larva L3 12hr old		238
larva L3 puffstage 1-2		100
larva L3 puffstage 3-6		80
larva L3 puffstage 7-9		85
white prepupae new		83
white prepupae 12hr		70
white prepupae 24hr		81
pupae 2d postWPP		75
pupae 3d postWPP		71
pupae 4d postWPP		79
adult male 01day		131
adult male 05day		132
adult male 30day		121
adult female 01day		190
adult female 05day		206
adult female 30day		201
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(177)
embryo 02-04hr		(59)
embryo 04-06hr		(87)
embryo 06-08hr		(90)
embryo 08-10hr		(91)
embryo 10-12hr		(123)
embryo 12-14hr		(72)
embryo 14-16hr		(78)
embryo 16-18hr		(84)
embryo 18-20hr		(93)
embryo 20-22hr		(130)
embryo 22-24hr		(127)
larva L1		(228)
larva L2		(260)
larva L3 12hr old		(238)
larva L3 puffstage 1-2		(100)
larva L3 puffstage 3-6		(80)
larva L3 puffstage 7-9		(85)
white prepupae new		(83)
white prepupae 12hr		(70)
white prepupae 24hr		(81)
pupae 2d postWPP		(75)
pupae 3d postWPP		(71)
pupae 4d postWPP		(79)
adult male 01day		(131)
adult male 05day		(132)
adult male 30day		(121)
adult female 01day		(190)
adult female 05day		(206)
adult female 30day		(201)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(177)
embryo 02-04hr		59
embryo 04-06hr		87
embryo 06-08hr		90
embryo 08-10hr		91
embryo 10-12hr		123
embryo 12-14hr		72
embryo 14-16hr		78
embryo 16-18hr		84
embryo 18-20hr		93
embryo 20-22hr		130
embryo 22-24hr		127
larva L1		(228)
larva L2		(260)
larva L3 12hr old		(238)
larva L3 puffstage 1-2		100
larva L3 puffstage 3-6		80
larva L3 puffstage 7-9		85
white prepupae new		83
white prepupae 12hr		70
white prepupae 24hr		81
pupae 2d postWPP		75
pupae 3d postWPP		71
pupae 4d postWPP		79
adult male 01day		131
adult male 05day		132
adult male 30day		121
adult female 01day		(190)
adult female 05day		(206)
adult female 30day		(201)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		177
embryo 02-04hr		59
embryo 04-06hr		87
embryo 06-08hr		90
embryo 08-10hr		91
embryo 10-12hr		123
embryo 12-14hr		72
embryo 14-16hr		78
embryo 16-18hr		84
embryo 18-20hr		93
embryo 20-22hr		130
embryo 22-24hr		127
larva L1		228
larva L2		260
larva L3 12hr old		238
larva L3 puffstage 1-2		100
larva L3 puffstage 3-6		80
larva L3 puffstage 7-9		85
white prepupae new		83
white prepupae 12hr		70
white prepupae 24hr		81
pupae 2d postWPP		75
pupae 3d postWPP		71
pupae 4d postWPP		79
adult male 01day		131
adult male 05day		132
adult male 30day		121
adult female 01day		190
adult female 05day		206
adult female 30day		201
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		189
Schneider line 2 Sg4		271
embryonic 1182-4H		103
embryonic GM2		99
embryonic Kc167		87
embryonic S1		94
embryonic S3		206
leg disc CME L1		199
wing disc CME-W2		228
wing disc ML-DmD8		150
wing disc ML-DmD9		132
wing disc ML-DmD16-c3		153
wing disc ML-DmD21		382
wing disc ML-DmD32		108
haltere disc ML-DmD17-c3		177
eye-antennal disc ML-DmD11		220
antennal disc ML-DmD20-c5		284
mixed discs ML-DmD4-c1		173
CNS ML-DmBG1-c1		210
CNS ML-DmBG2-c2		143
tumorous blood cells mbn2		96
ovary fGS/OSS		105
ovary OSC		109
ovary OSS		60
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(189)
Schneider line 2 Sg4		(271)
embryonic 1182-4H		(103)
embryonic GM2		(99)
embryonic Kc167		(87)
embryonic S1		(94)
embryonic S3		(206)
leg disc CME L1		(199)
wing disc CME-W2		(228)
wing disc ML-DmD8		(150)
wing disc ML-DmD9		(132)
wing disc ML-DmD16-c3		(153)
wing disc ML-DmD21		(382)
wing disc ML-DmD32		(108)
haltere disc ML-DmD17-c3		(177)
eye-antennal disc ML-DmD11		(220)
antennal disc ML-DmD20-c5		(284)
mixed discs ML-DmD4-c1		(173)
CNS ML-DmBG1-c1		(210)
CNS ML-DmBG2-c2		(143)
tumorous blood cells mbn2		(96)
ovary fGS/OSS		(105)
ovary OSC		(109)
ovary OSS		(60)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(189)
Schneider line 2 Sg4		(271)
embryonic 1182-4H		103
embryonic GM2		99
embryonic Kc167		87
embryonic S1		94
embryonic S3		(206)
leg disc CME L1		(199)
wing disc CME-W2		(228)
wing disc ML-DmD8		(150)
wing disc ML-DmD9		(132)
wing disc ML-DmD16-c3		(153)
wing disc ML-DmD21		(382)
wing disc ML-DmD32		(108)
haltere disc ML-DmD17-c3		(177)
eye-antennal disc ML-DmD11		(220)
antennal disc ML-DmD20-c5		(284)
mixed discs ML-DmD4-c1		(173)
CNS ML-DmBG1-c1		(210)
CNS ML-DmBG2-c2		(143)
tumorous blood cells mbn2		96
ovary fGS/OSS		105
ovary OSC		(109)
ovary OSS		60
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		189
Schneider line 2 Sg4		271
embryonic 1182-4H		103
embryonic GM2		99
embryonic Kc167		87
embryonic S1		94
embryonic S3		206
leg disc CME L1		199
wing disc CME-W2		228
wing disc ML-DmD8		150
wing disc ML-DmD9		132
wing disc ML-DmD16-c3		153
wing disc ML-DmD21		382
wing disc ML-DmD32		108
haltere disc ML-DmD17-c3		177
eye-antennal disc ML-DmD11		220
antennal disc ML-DmD20-c5		284
mixed discs ML-DmD4-c1		173
CNS ML-DmBG1-c1		210
CNS ML-DmBG2-c2		143
tumorous blood cells mbn2		96
ovary fGS/OSS		105
ovary OSC		109
ovary OSS		60
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		189
Schneider line 2 Sg4		271
embryonic 1182-4H		103
embryonic GM2		99
embryonic Kc167		87
embryonic S1		94
embryonic S3		206
leg disc CME L1		199
wing disc CME-W2		228
wing disc ML-DmD8		150
wing disc ML-DmD9		132
wing disc ML-DmD16-c3		153
wing disc ML-DmD21		382
wing disc ML-DmD32		108
haltere disc ML-DmD17-c3		177
eye-antennal disc ML-DmD11		220
antennal disc ML-DmD20-c5		284
mixed discs ML-DmD4-c1		173
CNS ML-DmBG1-c1		210
CNS ML-DmBG2-c2		143
tumorous blood cells mbn2		96
ovary fGS/OSS		105
ovary OSC		109
ovary OSS		60
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(189)
Schneider line 2 Sg4		(271)
embryonic 1182-4H		(103)
embryonic GM2		(99)
embryonic Kc167		(87)
embryonic S1		(94)
embryonic S3		(206)
leg disc CME L1		(199)
wing disc CME-W2		(228)
wing disc ML-DmD8		(150)
wing disc ML-DmD9		(132)
wing disc ML-DmD16-c3		(153)
wing disc ML-DmD21		(382)
wing disc ML-DmD32		(108)
haltere disc ML-DmD17-c3		(177)
eye-antennal disc ML-DmD11		(220)
antennal disc ML-DmD20-c5		(284)
mixed discs ML-DmD4-c1		(173)
CNS ML-DmBG1-c1		(210)
CNS ML-DmBG2-c2		(143)
tumorous blood cells mbn2		(96)
ovary fGS/OSS		(105)
ovary OSC		(109)
ovary OSS		(60)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(189)
Schneider line 2 Sg4		(271)
embryonic 1182-4H		103
embryonic GM2		99
embryonic Kc167		87
embryonic S1		94
embryonic S3		(206)
leg disc CME L1		(199)
wing disc CME-W2		(228)
wing disc ML-DmD8		(150)
wing disc ML-DmD9		132
wing disc ML-DmD16-c3		(153)
wing disc ML-DmD21		(382)
wing disc ML-DmD32		108
haltere disc ML-DmD17-c3		(177)
eye-antennal disc ML-DmD11		(220)
antennal disc ML-DmD20-c5		(284)
mixed discs ML-DmD4-c1		(173)
CNS ML-DmBG1-c1		(210)
CNS ML-DmBG2-c2		143
tumorous blood cells mbn2		96
ovary fGS/OSS		105
ovary OSC		109
ovary OSS		60
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		189
Schneider line 2 Sg4		271
embryonic 1182-4H		103
embryonic GM2		99
embryonic Kc167		87
embryonic S1		94
embryonic S3		206
leg disc CME L1		199
wing disc CME-W2		228
wing disc ML-DmD8		150
wing disc ML-DmD9		132
wing disc ML-DmD16-c3		153
wing disc ML-DmD21		382
wing disc ML-DmD32		108
haltere disc ML-DmD17-c3		177
eye-antennal disc ML-DmD11		220
antennal disc ML-DmD20-c5		284
mixed discs ML-DmD4-c1		173
CNS ML-DmBG1-c1		210
CNS ML-DmBG2-c2		143
tumorous blood cells mbn2		96
ovary fGS/OSS		105
ovary OSC		109
ovary OSS		60
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		50
cold shock, 4-day adult		37
heat shock, 4-day adult		131
Cadmium 50 mM 6 hrs, larvae L3		186
Cadmium 50 mM 12 hrs, larvae L3		101
Cadmium 50 mM 48 hrs, 4-day adult		131
Cadmium 100 mM 48 hrs, 4-day adult		100
Copper 0.5 mM 12 hrs, larvae L3		85
Copper 15 mM 48 hrs, 4-day adult		85
Zinc 5 mM 12 hrs, larvae L3		57
Zinc 4.5 mM 48 hrs, 4-day adult		66
Ethanol 2.5% 3 hrs, larvae L3		139
Ethanol 5% 3 hrs, larvae L3		185
Ethanol 10% 3 hrs, larvae L3		159
Caffeine 1.5 mg/ml 4 hrs, larvae L3		124
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		123
Caffeine 25 mg/ml 48 hrs, 4-day adult		46
Paraquat 5 mM 48 hrs, 4-day adult		125
Paraquat 10 mM 48 hrs, 4-day adult		121
Rotenone 2 μg 12 hrs, larvae L3		195
Rotenone 8 μg 12 hrs, larvae L3		209
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(50)
cold shock, 4-day adult		(37)
heat shock, 4-day adult		(131)
Cadmium 50 mM 6 hrs, larvae L3		(186)
Cadmium 50 mM 12 hrs, larvae L3		(101)
Cadmium 50 mM 48 hrs, 4-day adult		(131)
Cadmium 100 mM 48 hrs, 4-day adult		(100)
Copper 0.5 mM 12 hrs, larvae L3		(85)
Copper 15 mM 48 hrs, 4-day adult		(85)
Zinc 5 mM 12 hrs, larvae L3		(57)
Zinc 4.5 mM 48 hrs, 4-day adult		(66)
Ethanol 2.5% 3 hrs, larvae L3		(139)
Ethanol 5% 3 hrs, larvae L3		(185)
Ethanol 10% 3 hrs, larvae L3		(159)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(124)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(123)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(46)
Paraquat 5 mM 48 hrs, 4-day adult		(125)
Paraquat 10 mM 48 hrs, 4-day adult		(121)
Rotenone 2 μg 12 hrs, larvae L3		(195)
Rotenone 8 μg 12 hrs, larvae L3		(209)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		50
cold shock, 4-day adult		37
heat shock, 4-day adult		(131)
Cadmium 50 mM 6 hrs, larvae L3		(186)
Cadmium 50 mM 12 hrs, larvae L3		101
Cadmium 50 mM 48 hrs, 4-day adult		(131)
Cadmium 100 mM 48 hrs, 4-day adult		100
Copper 0.5 mM 12 hrs, larvae L3		85
Copper 15 mM 48 hrs, 4-day adult		85
Zinc 5 mM 12 hrs, larvae L3		57
Zinc 4.5 mM 48 hrs, 4-day adult		66
Ethanol 2.5% 3 hrs, larvae L3		(139)
Ethanol 5% 3 hrs, larvae L3		(185)
Ethanol 10% 3 hrs, larvae L3		(159)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(124)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(123)
Caffeine 25 mg/ml 48 hrs, 4-day adult		46
Paraquat 5 mM 48 hrs, 4-day adult		(125)
Paraquat 10 mM 48 hrs, 4-day adult		(121)
Rotenone 2 μg 12 hrs, larvae L3		(195)
Rotenone 8 μg 12 hrs, larvae L3		(209)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		50
cold shock, 4-day adult		37
heat shock, 4-day adult		131
Cadmium 50 mM 6 hrs, larvae L3		186
Cadmium 50 mM 12 hrs, larvae L3		101
Cadmium 50 mM 48 hrs, 4-day adult		131
Cadmium 100 mM 48 hrs, 4-day adult		100
Copper 0.5 mM 12 hrs, larvae L3		85
Copper 15 mM 48 hrs, 4-day adult		85
Zinc 5 mM 12 hrs, larvae L3		57
Zinc 4.5 mM 48 hrs, 4-day adult		66
Ethanol 2.5% 3 hrs, larvae L3		139
Ethanol 5% 3 hrs, larvae L3		185
Ethanol 10% 3 hrs, larvae L3		159
Caffeine 1.5 mg/ml 4 hrs, larvae L3		124
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		123
Caffeine 25 mg/ml 48 hrs, 4-day adult		46
Paraquat 5 mM 48 hrs, 4-day adult		125
Paraquat 10 mM 48 hrs, 4-day adult		121
Rotenone 2 μg 12 hrs, larvae L3		195
Rotenone 8 μg 12 hrs, larvae L3		209
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		50
cold shock, 4-day adult		37
heat shock, 4-day adult		131
Cadmium 50 mM 6 hrs, larvae L3		186
Cadmium 50 mM 12 hrs, larvae L3		101
Cadmium 50 mM 48 hrs, 4-day adult		131
Cadmium 100 mM 48 hrs, 4-day adult		100
Copper 0.5 mM 12 hrs, larvae L3		85
Copper 15 mM 48 hrs, 4-day adult		85
Zinc 5 mM 12 hrs, larvae L3		57
Zinc 4.5 mM 48 hrs, 4-day adult		66
Ethanol 2.5% 3 hrs, larvae L3		139
Ethanol 5% 3 hrs, larvae L3		185
Ethanol 10% 3 hrs, larvae L3		159
Caffeine 1.5 mg/ml 4 hrs, larvae L3		124
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		123
Caffeine 25 mg/ml 48 hrs, 4-day adult		46
Paraquat 5 mM 48 hrs, 4-day adult		125
Paraquat 10 mM 48 hrs, 4-day adult		121
Rotenone 2 μg 12 hrs, larvae L3		195
Rotenone 8 μg 12 hrs, larvae L3		209
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(50)
cold shock, 4-day adult		(37)
heat shock, 4-day adult		(131)
Cadmium 50 mM 6 hrs, larvae L3		(186)
Cadmium 50 mM 12 hrs, larvae L3		(101)
Cadmium 50 mM 48 hrs, 4-day adult		(131)
Cadmium 100 mM 48 hrs, 4-day adult		(100)
Copper 0.5 mM 12 hrs, larvae L3		(85)
Copper 15 mM 48 hrs, 4-day adult		(85)
Zinc 5 mM 12 hrs, larvae L3		(57)
Zinc 4.5 mM 48 hrs, 4-day adult		(66)
Ethanol 2.5% 3 hrs, larvae L3		(139)
Ethanol 5% 3 hrs, larvae L3		(185)
Ethanol 10% 3 hrs, larvae L3		(159)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(124)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(123)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(46)
Paraquat 5 mM 48 hrs, 4-day adult		(125)
Paraquat 10 mM 48 hrs, 4-day adult		(121)
Rotenone 2 μg 12 hrs, larvae L3		(195)
Rotenone 8 μg 12 hrs, larvae L3		(209)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		50
cold shock, 4-day adult		37
heat shock, 4-day adult		131
Cadmium 50 mM 6 hrs, larvae L3		(186)
Cadmium 50 mM 12 hrs, larvae L3		101
Cadmium 50 mM 48 hrs, 4-day adult		131
Cadmium 100 mM 48 hrs, 4-day adult		100
Copper 0.5 mM 12 hrs, larvae L3		85
Copper 15 mM 48 hrs, 4-day adult		85
Zinc 5 mM 12 hrs, larvae L3		57
Zinc 4.5 mM 48 hrs, 4-day adult		66
Ethanol 2.5% 3 hrs, larvae L3		139
Ethanol 5% 3 hrs, larvae L3		(185)
Ethanol 10% 3 hrs, larvae L3		(159)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		124
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		123
Caffeine 25 mg/ml 48 hrs, 4-day adult		46
Paraquat 5 mM 48 hrs, 4-day adult		125
Paraquat 10 mM 48 hrs, 4-day adult		121
Rotenone 2 μg 12 hrs, larvae L3		(195)
Rotenone 8 μg 12 hrs, larvae L3		(209)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		50
cold shock, 4-day adult		37
heat shock, 4-day adult		131
Cadmium 50 mM 6 hrs, larvae L3		186
Cadmium 50 mM 12 hrs, larvae L3		101
Cadmium 50 mM 48 hrs, 4-day adult		131
Cadmium 100 mM 48 hrs, 4-day adult		100
Copper 0.5 mM 12 hrs, larvae L3		85
Copper 15 mM 48 hrs, 4-day adult		85
Zinc 5 mM 12 hrs, larvae L3		57
Zinc 4.5 mM 48 hrs, 4-day adult		66
Ethanol 2.5% 3 hrs, larvae L3		139
Ethanol 5% 3 hrs, larvae L3		185
Ethanol 10% 3 hrs, larvae L3		159
Caffeine 1.5 mg/ml 4 hrs, larvae L3		124
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		123
Caffeine 25 mg/ml 48 hrs, 4-day adult		46
Paraquat 5 mM 48 hrs, 4-day adult		125
Paraquat 10 mM 48 hrs, 4-day adult		121
Rotenone 2 μg 12 hrs, larvae L3		195
Rotenone 8 μg 12 hrs, larvae L3		209
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

RE37074

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0016687

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG4634-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal, with Scer\GAL4^pnr-MD237

Nurf-38^GD1625

lethal | recessive

Nurf-38^k16102

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of Nurf-38	Class	Mutagen	Stocks	Known lesion
Nurf-38^k16102		P-element activity	2	--
Nurf-38¹			0	--

Alleles Carried on Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Nurf-38	Mutagen	Stocks	Known lesion
Nurf-38^GD1625	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Nurf-38^GL00369	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Nurf-38^JF01299	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Nurf-38^KK102637	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Nurf-38^NIG.4634R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes