• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Oscp

General Information
Symbol	Dmel\Oscp	Species	D. melanogaster
Name	Oligomycin sensitivity-conferring protein	Annotation symbol	CG4307
Feature type	protein_coding_gene	FlyBase ID	FBgn0016691
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map	3-
Cytogenetic map	88E8-88E9	Sequence location	3R:11,091,313..11,092,412 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Oligomycin sensitivity-conferring protein is referred to in FlyBase by the symbol Dmel\Oscp (CG4307, FBgn0016691). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: hydrogen-exporting ATPase activity, phosphorylative mechanism. Based on sequence similarity, it is predicted to be involved in the biological process: proton transport. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: ATPase, F1 complex, OSCP/delta subunit; F1F0 ATP synthase OSCP/delta subunit, N-terminal domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1631750_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Oscp. Gene sequence location is 3R:11091313..11092412.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 88E8-88E9   Limits computationally determined from genome sequence between P{lacW}Hsc70-4L3929 and P{lacW}MRG15j6A3
Experimentally Determined Cytological Location
Cytogenetic map Notes References 88E-88E     (Caggese, 1996.7.30) 88E7-88E10   (determined by in situ hybridisation)   (Caggese et al., 1999)
Experimentally Determined Recombination Data
Location	3- (Caggese, 1996.7.30)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Oscp for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Oscp-RA FBtr0083063  NM_079634   802   209 Oscp-RB FBtr0083064  NM_169631   862   126
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Oscp-PA   FBpp0082522   22.4   209   10.24     NP_524358   AAF55156 Oscp-PB   FBpp0082523   13.5   126   9.78     NP_731995   AAN13642
Additional Polypeptide Data & Comments
Reported size (kDa)	209 (aa) (Caggese et al., 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ATPase, F1 complex, OSCP/delta subunit (IPR000711) F1F0 ATP synthase OSCP/delta subunit, N-terminal domain (IPR026015) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME04307
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA696040   AA735466   AA949931   AE014297 AAF55156   AE014297 AAN13642   AI062534   AI109495   AI257094   AI386629   AI386683   AI387132   AI402562   AI402903   AI404902   AI405958   AI513120   AI513680   AI513868   AI514153   AI516256   AI517762   AI531432   AY058261 AAL13490   BF487895   BF489611   BG637279   BI163988   BI170632   BI228222   BI228356   BI229895   BI238894   BI239127   BI240908   BI242178   BI242745   BI352267   BI352270   BI355593   BI358267   BI364986   BI365008   BI366201   BI366944   BI369715   BI373051   BI563346   BI563476   BI566124   BI566564   BI566673   BI567242   BI567493   BI567555   BI568039   BI568144   BI569658   BI570031   BI570735   BI571278   BI571329   BI571382   BI575174   BI575415   BI575417   BI575705   BI576880   BI580657   BI581162   BI581178   BI581290   BI581304   BI582045   BI582821   BI583537   BI584019   BI584123   BI585380   BI585383   BI585852   BI585942   BI586153   BI586935   BI587343   BI588496   BI591392   BI592064   BI593566   BI605954   BI606141   BI606232   BI611126   BI612532   BI612880   BI613539   BI613798   BI613975   BI614206   BI614471   BI614672   BI614931   BI614977   BI615234   BI619089   BI620597   BI621209   BI623228   BI625787   BI627393   BI627813   BI629467   BI630862   BI631125   BI631812   BI631886   BI636410   BP546799   BP547481   BP548338   BP549300   BP549301   BP550363   BP550364   BP550880   BP550881   BP551365   BP551366   BP553271   BP553272   BP553879   BP553880   BP554446   BP554447   BP556164   BP556165   BP558906   BP558907   BP559222   BP559223   BP560269   BP560270   BT003799   CA803753   CA807701   CK605291   CK605292   CK661655   CO156207   CO268371   CO325456   CO334002   EC090801   EC205437   EC212296   EC231592   EC235388   EC265768   EV575514   EV576157   EV577047   EV579462   EV580003   EV580111   EV584325   EV588742   EV592560   GH749262   GH750649   GH771198   GH772010   GH774981   GH775778   GH778269   GH780801   GH782315   GH792395   GH793032   GH795078   GH802671   GH802884   GH803052   GH810403   GH815862   GH817151   GH817936   GH831453   GH845483   GH849399   GH853859   GH856296   GH864062   GH864935   GH871561   GH874542   GH882002   GH895360   GH901392   GH903077   GH906590   GH917119   GH919850   GH926403   GH936270   X99666 CAA67980
UniProtKB/Swiss-Prot	Q24439
UniProtKB/TrEMBL	Q8INE6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) dorsal pharyngeal muscle primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) Malpighian tubule primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) visceral muscle primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic anal pad   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic large intestine   (Fisher et al., 2012) embryonic Malpighian tubule   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010) day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006, Cermelli et al., 2006) mitochondrion inferred from direct assay (Alonso et al., 2005)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1580.35 Larval Midgut    3199.5 Larval Hindgut    3282 Larval Malpighian Tubules    2882.2 Larval Fat Body    1586.1 Larval Salivary Gland    2782.2 Larval Trachea    2432.275 Larval Carcass    3230.65 Adult Head    2885.3 Adult Eye    3295.8 Adult Brain    2043.5 Adult Thoracic-Abdominal Ganglion    2716.8 Adult Crop    2808.1 Adult Midgut    2909.2 Adult Hindgut    3772.4 Adult Malpighian Tubules    3427.2 Adult Fat Body    3601.1 Adult Salivary Gland    4063.1 Adult Heart    4173.35 Adult VirginFemale Spermatheca    3181.1 Adult InseminatedFemale Spermatheca    2952.1 Adult Ovary    1597.8 Adult Testis    491.2 Adult Male Accessory Gland    1462.1 Adult Carcass    5177.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1580.35) Larval Midgut  (3199.5) Larval Hindgut  (3282) Larval Malpighian Tubules  (2882.2) Larval Fat Body  (1586.1) Larval Salivary Gland  (2782.2) Larval Trachea  (2432.275) Larval Carcass  (3230.65) Adult Head  (2885.3) Adult Eye  (3295.8) Adult Brain  (2043.5) Adult Thoracic-Abdominal Ganglion  (2716.8) Adult Crop  (2808.1) Adult Midgut  (2909.2) Adult Hindgut  (3772.4) Adult Malpighian Tubules  (3427.2) Adult Fat Body  (3601.1) Adult Salivary Gland  (4063.1) Adult Heart  (4173.35) Adult VirginFemale Spermatheca  (3181.1) Adult InseminatedFemale Spermatheca  (2952.1) Adult Ovary  (1597.8) Adult Testis    491.2 Adult Male Accessory Gland  (1462.1) Adult Carcass  (5177.1) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1580.35) Larval Midgut  (3199.5) Larval Hindgut  (3282) Larval Malpighian Tubules  (2882.2) Larval Fat Body  (1586.1) Larval Salivary Gland  (2782.2) Larval Trachea  (2432.275) Larval Carcass  (3230.65) Adult Head  (2885.3) Adult Eye  (3295.8) Adult Brain  (2043.5) Adult Thoracic-Abdominal Ganglion  (2716.8) Adult Crop  (2808.1) Adult Midgut  (2909.2) Adult Hindgut  (3772.4) Adult Malpighian Tubules  (3427.2) Adult Fat Body  (3601.1) Adult Salivary Gland  (4063.1) Adult Heart  (4173.35) Adult VirginFemale Spermatheca  (3181.1) Adult InseminatedFemale Spermatheca  (2952.1) Adult Ovary  (1597.8) Adult Testis    491.2 Adult Male Accessory Gland  (1462.1) Adult Carcass  (5177.1) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1580.35 Larval Midgut    3199.5 Larval Hindgut    3282 Larval Malpighian Tubules    2882.2 Larval Fat Body    1586.1 Larval Salivary Gland    2782.2 Larval Trachea    2432.275 Larval Carcass    3230.65 Adult Head    2885.3 Adult Eye    3295.8 Adult Brain    2043.5 Adult Thoracic-Abdominal Ganglion    2716.8 Adult Crop    2808.1 Adult Midgut    2909.2 Adult Hindgut    3772.4 Adult Malpighian Tubules    3427.2 Adult Fat Body    3601.1 Adult Salivary Gland    4063.1 Adult Heart    4173.35 Adult VirginFemale Spermatheca    3181.1 Adult InseminatedFemale Spermatheca    2952.1 Adult Ovary    1597.8 Adult Testis    491.2 Adult Male Accessory Gland    1462.1 Adult Carcass    5177.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1580.35 Larval Midgut    3199.5 Larval Hindgut    3282 Larval Malpighian Tubules    2882.2 Larval Fat Body    1586.1 Larval Salivary Gland    2782.2 Larval Trachea    2432.275 Larval Carcass    3230.65 Adult Head    2885.3 Adult Eye    3295.8 Adult Brain    2043.5 Adult Thoracic-Abdominal Ganglion    2716.8 Adult Crop    2808.1 Adult Midgut    2909.2 Adult Hindgut    3772.4 Adult Malpighian Tubules    3427.2 Adult Fat Body    3601.1 Adult Salivary Gland    4063.1 Adult Heart    4173.35 Adult VirginFemale Spermatheca    3181.1 Adult InseminatedFemale Spermatheca    2952.1 Adult Ovary    1597.8 Adult Testis    491.2 Adult Male Accessory Gland    1462.1 Adult Carcass    5177.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1580.35) Larval Midgut  (3199.5) Larval Hindgut  (3282) Larval Malpighian Tubules  (2882.2) Larval Fat Body  (1586.1) Larval Salivary Gland  (2782.2) Larval Trachea  (2432.275) Larval Carcass  (3230.65) Adult Head  (2885.3) Adult Eye  (3295.8) Adult Brain  (2043.5) Adult Thoracic-Abdominal Ganglion  (2716.8) Adult Crop  (2808.1) Adult Midgut  (2909.2) Adult Hindgut  (3772.4) Adult Malpighian Tubules  (3427.2) Adult Fat Body  (3601.1) Adult Salivary Gland  (4063.1) Adult Heart  (4173.35) Adult VirginFemale Spermatheca  (3181.1) Adult InseminatedFemale Spermatheca  (2952.1) Adult Ovary  (1597.8) Adult Testis    491.2 Adult Male Accessory Gland  (1462.1) Adult Carcass  (5177.1) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1580.35 Larval Midgut  (3199.5) Larval Hindgut  (3282) Larval Malpighian Tubules  (2882.2) Larval Fat Body  1586.1 Larval Salivary Gland  (2782.2) Larval Trachea  (2432.275) Larval Carcass  (3230.65) Adult Head  (2885.3) Adult Eye  (3295.8) Adult Brain  (2043.5) Adult Thoracic-Abdominal Ganglion  (2716.8) Adult Crop  (2808.1) Adult Midgut  (2909.2) Adult Hindgut  (3772.4) Adult Malpighian Tubules  (3427.2) Adult Fat Body  (3601.1) Adult Salivary Gland  (4063.1) Adult Heart  (4173.35) Adult VirginFemale Spermatheca  (3181.1) Adult InseminatedFemale Spermatheca  (2952.1) Adult Ovary  1597.8 Adult Testis    491.2 Adult Male Accessory Gland  1462.1 Adult Carcass  (5177.1) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1580.35 Larval Midgut    3199.5 Larval Hindgut    3282 Larval Malpighian Tubules    2882.2 Larval Fat Body    1586.1 Larval Salivary Gland    2782.2 Larval Trachea    2432.275 Larval Carcass    3230.65 Adult Head    2885.3 Adult Eye    3295.8 Adult Brain    2043.5 Adult Thoracic-Abdominal Ganglion    2716.8 Adult Crop    2808.1 Adult Midgut    2909.2 Adult Hindgut    3772.4 Adult Malpighian Tubules    3427.2 Adult Fat Body    3601.1 Adult Salivary Gland    4063.1 Adult Heart    4173.35 Adult VirginFemale Spermatheca    3181.1 Adult InseminatedFemale Spermatheca    2952.1 Adult Ovary    1597.8 Adult Testis    491.2 Adult Male Accessory Gland    1462.1 Adult Carcass    5177.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    2885.3   NA  Eye    3295.8   NA  Brain    2043.5   1580.35  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    2716.8   NA  Crop    2808.1   3199.5  Midgut    2909.2   3282  Hindgut    3772.4   2882.2  Malpighian Tubules    3427.2   1586.1  Fat Body    3601.1   2782.2  Salivary Gland    4063.1   NA  Heart    4173.35   2432.275  Trachea    NA   NA  VirginFemale Spermatheca    3181.1   NA  InseminatedFemale Spermatheca    2952.1   NA  Ovary    1597.8   NA  Testis    491.2   NA  Male Accessory Gland    1462.1   3230.65  Carcass    5177.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    230 central nervous system, larvae L3    157 central nervous system, pupae P8    166 head, virgin 1-day female    477 head, virgin 4-day female    246 head, virgin 20-day female    227 head, mated 1-day female    419 head, mated 4-day female    188 head, mated 20-day female    190 head, mated 1-day male    531 head, mated 4-day male    265 head, mated 20-day male    306 salivary gland, larvae L3 wandering    53 salivary gland, white prepupae    109 digestive system, larvae L3 wandering    137 digestive system, 1-day adult    388 digestive system, 4-day adult    235 digestive system, 20-day adult    204 fat body, larvae L3 wandering    70 fat body, white prepupae    54 fat body, pupae P8    182 carcass, larvae L3 wandering    130 carcass, 1-day adult    1142 carcass, 4-day adult    503 carcass, 20-day adult    333 ovary, virgin 4-day female    178 ovary, mated 4-day female    154 testis, mated 4-day male    258 accessory gland, mated 4-day male    144 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (230) central nervous system, larvae L3  (157) central nervous system, pupae P8  (166) head, virgin 1-day female  (477) head, virgin 4-day female  (246) head, virgin 20-day female  (227) head, mated 1-day female  (419) head, mated 4-day female  (188) head, mated 20-day female  (190) head, mated 1-day male  (531) head, mated 4-day male  (265) head, mated 20-day male  (306) salivary gland, larvae L3 wandering  (53) salivary gland, white prepupae  (109) digestive system, larvae L3 wandering  (137) digestive system, 1-day adult  (388) digestive system, 4-day adult  (235) digestive system, 20-day adult  (204) fat body, larvae L3 wandering  (70) fat body, white prepupae  (54) fat body, pupae P8  (182) carcass, larvae L3 wandering  (130) carcass, 1-day adult  (1142) carcass, 4-day adult  (503) carcass, 20-day adult  (333) ovary, virgin 4-day female  (178) ovary, mated 4-day female  (154) testis, mated 4-day male  (258) accessory gland, mated 4-day male  (144) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (230) central nervous system, larvae L3  (157) central nervous system, pupae P8  (166) head, virgin 1-day female  (477) head, virgin 4-day female  (246) head, virgin 20-day female  (227) head, mated 1-day female  (419) head, mated 4-day female  (188) head, mated 20-day female  (190) head, mated 1-day male  (531) head, mated 4-day male  (265) head, mated 20-day male  (306) salivary gland, larvae L3 wandering    53 salivary gland, white prepupae  (109) digestive system, larvae L3 wandering  (137) digestive system, 1-day adult  (388) digestive system, 4-day adult  (235) digestive system, 20-day adult  (204) fat body, larvae L3 wandering    70 fat body, white prepupae    54 fat body, pupae P8  (182) carcass, larvae L3 wandering  (130) carcass, 1-day adult  (1142) carcass, 4-day adult  (503) carcass, 20-day adult  (333) ovary, virgin 4-day female  (178) ovary, mated 4-day female  (154) testis, mated 4-day male  (258) accessory gland, mated 4-day male  (144) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    230 central nervous system, larvae L3    157 central nervous system, pupae P8    166 head, virgin 1-day female    477 head, virgin 4-day female    246 head, virgin 20-day female    227 head, mated 1-day female    419 head, mated 4-day female    188 head, mated 20-day female    190 head, mated 1-day male    531 head, mated 4-day male    265 head, mated 20-day male    306 salivary gland, larvae L3 wandering    53 salivary gland, white prepupae    109 digestive system, larvae L3 wandering    137 digestive system, 1-day adult    388 digestive system, 4-day adult    235 digestive system, 20-day adult    204 fat body, larvae L3 wandering    70 fat body, white prepupae    54 fat body, pupae P8    182 carcass, larvae L3 wandering    130 carcass, 1-day adult    1142 carcass, 4-day adult    503 carcass, 20-day adult    333 ovary, virgin 4-day female    178 ovary, mated 4-day female    154 testis, mated 4-day male    258 accessory gland, mated 4-day male    144 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    230 central nervous system, larvae L3    157 central nervous system, pupae P8    166 head, virgin 1-day female    477 head, virgin 4-day female    246 head, virgin 20-day female    227 head, mated 1-day female    419 head, mated 4-day female    188 head, mated 20-day female    190 head, mated 1-day male    531 head, mated 4-day male    265 head, mated 20-day male    306 salivary gland, larvae L3 wandering    53 salivary gland, white prepupae    109 digestive system, larvae L3 wandering    137 digestive system, 1-day adult    388 digestive system, 4-day adult    235 digestive system, 20-day adult    204 fat body, larvae L3 wandering    70 fat body, white prepupae    54 fat body, pupae P8    182 carcass, larvae L3 wandering    130 carcass, 1-day adult    1142 carcass, 4-day adult    503 carcass, 20-day adult    333 ovary, virgin 4-day female    178 ovary, mated 4-day female    154 testis, mated 4-day male    258 accessory gland, mated 4-day male    144 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (230) central nervous system, larvae L3  (157) central nervous system, pupae P8  (166) head, virgin 1-day female  (477) head, virgin 4-day female  (246) head, virgin 20-day female  (227) head, mated 1-day female  (419) head, mated 4-day female  (188) head, mated 20-day female  (190) head, mated 1-day male  (531) head, mated 4-day male  (265) head, mated 20-day male  (306) salivary gland, larvae L3 wandering  (53) salivary gland, white prepupae  (109) digestive system, larvae L3 wandering  (137) digestive system, 1-day adult  (388) digestive system, 4-day adult  (235) digestive system, 20-day adult  (204) fat body, larvae L3 wandering  (70) fat body, white prepupae  (54) fat body, pupae P8  (182) carcass, larvae L3 wandering  (130) carcass, 1-day adult  (1142) carcass, 4-day adult  (503) carcass, 20-day adult  (333) ovary, virgin 4-day female  (178) ovary, mated 4-day female  (154) testis, mated 4-day male  (258) accessory gland, mated 4-day male  (144) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (230) central nervous system, larvae L3  (157) central nervous system, pupae P8  (166) head, virgin 1-day female  (477) head, virgin 4-day female  (246) head, virgin 20-day female  (227) head, mated 1-day female  (419) head, mated 4-day female  (188) head, mated 20-day female  (190) head, mated 1-day male  (531) head, mated 4-day male  (265) head, mated 20-day male  (306) salivary gland, larvae L3 wandering    53 salivary gland, white prepupae  109 digestive system, larvae L3 wandering  137 digestive system, 1-day adult  (388) digestive system, 4-day adult  (235) digestive system, 20-day adult  (204) fat body, larvae L3 wandering    70 fat body, white prepupae    54 fat body, pupae P8  (182) carcass, larvae L3 wandering  130 carcass, 1-day adult  (1142) carcass, 4-day adult  (503) carcass, 20-day adult  (333) ovary, virgin 4-day female  (178) ovary, mated 4-day female  (154) testis, mated 4-day male  (258) accessory gland, mated 4-day male  (144) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    230 central nervous system, larvae L3    157 central nervous system, pupae P8    166 head, virgin 1-day female    477 head, virgin 4-day female    246 head, virgin 20-day female    227 head, mated 1-day female    419 head, mated 4-day female    188 head, mated 20-day female    190 head, mated 1-day male    531 head, mated 4-day male    265 head, mated 20-day male    306 salivary gland, larvae L3 wandering    53 salivary gland, white prepupae    109 digestive system, larvae L3 wandering    137 digestive system, 1-day adult    388 digestive system, 4-day adult    235 digestive system, 20-day adult    204 fat body, larvae L3 wandering    70 fat body, white prepupae    54 fat body, pupae P8    182 carcass, larvae L3 wandering    130 carcass, 1-day adult    1142 carcass, 4-day adult    503 carcass, 20-day adult    333 ovary, virgin 4-day female    178 ovary, mated 4-day female    154 testis, mated 4-day male    258 accessory gland, mated 4-day male    144 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    216 embryo 02-04hr    301 embryo 04-06hr    233 embryo 06-08hr    152 embryo 08-10hr    181 embryo 10-12hr    301 embryo 12-14hr    195 embryo 14-16hr    261 embryo 16-18hr    283 embryo 18-20hr    385 embryo 20-22hr    504 embryo 22-24hr    503 larva L1    615 larva L2    643 larva L3 12hr old    622 larva L3 puffstage 1-2    317 larva L3 puffstage 3-6    158 larva L3 puffstage 7-9    133 white prepupae new    122 white prepupae 12hr    110 white prepupae 24hr    119 pupae 2d postWPP    230 pupae 3d postWPP    652 pupae 4d postWPP    920 adult male 01day    926 adult male 05day    699 adult male 30day    291 adult female 01day    795 adult female 05day    338 adult female 30day    266 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (216) embryo 02-04hr  (301) embryo 04-06hr  (233) embryo 06-08hr  (152) embryo 08-10hr  (181) embryo 10-12hr  (301) embryo 12-14hr  (195) embryo 14-16hr  (261) embryo 16-18hr  (283) embryo 18-20hr  (385) embryo 20-22hr  (504) embryo 22-24hr  (503) larva L1  (615) larva L2  (643) larva L3 12hr old  (622) larva L3 puffstage 1-2  (317) larva L3 puffstage 3-6  (158) larva L3 puffstage 7-9  (133) white prepupae new  (122) white prepupae 12hr  (110) white prepupae 24hr  (119) pupae 2d postWPP  (230) pupae 3d postWPP  (652) pupae 4d postWPP  (920) adult male 01day  (926) adult male 05day  (699) adult male 30day  (291) adult female 01day  (795) adult female 05day  (338) adult female 30day  (266) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (216) embryo 02-04hr  (301) embryo 04-06hr  (233) embryo 06-08hr  (152) embryo 08-10hr  (181) embryo 10-12hr  (301) embryo 12-14hr  (195) embryo 14-16hr  (261) embryo 16-18hr  (283) embryo 18-20hr  (385) embryo 20-22hr  (504) embryo 22-24hr  (503) larva L1  (615) larva L2  (643) larva L3 12hr old  (622) larva L3 puffstage 1-2  (317) larva L3 puffstage 3-6  (158) larva L3 puffstage 7-9  (133) white prepupae new  (122) white prepupae 12hr  (110) white prepupae 24hr  (119) pupae 2d postWPP  (230) pupae 3d postWPP  (652) pupae 4d postWPP  (920) adult male 01day  (926) adult male 05day  (699) adult male 30day  (291) adult female 01day  (795) adult female 05day  (338) adult female 30day  (266) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    216 embryo 02-04hr    301 embryo 04-06hr    233 embryo 06-08hr    152 embryo 08-10hr    181 embryo 10-12hr    301 embryo 12-14hr    195 embryo 14-16hr    261 embryo 16-18hr    283 embryo 18-20hr    385 embryo 20-22hr    504 embryo 22-24hr    503 larva L1    615 larva L2    643 larva L3 12hr old    622 larva L3 puffstage 1-2    317 larva L3 puffstage 3-6    158 larva L3 puffstage 7-9    133 white prepupae new    122 white prepupae 12hr    110 white prepupae 24hr    119 pupae 2d postWPP    230 pupae 3d postWPP    652 pupae 4d postWPP    920 adult male 01day    926 adult male 05day    699 adult male 30day    291 adult female 01day    795 adult female 05day    338 adult female 30day    266 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    216 embryo 02-04hr    301 embryo 04-06hr    233 embryo 06-08hr    152 embryo 08-10hr    181 embryo 10-12hr    301 embryo 12-14hr    195 embryo 14-16hr    261 embryo 16-18hr    283 embryo 18-20hr    385 embryo 20-22hr    504 embryo 22-24hr    503 larva L1    615 larva L2    643 larva L3 12hr old    622 larva L3 puffstage 1-2    317 larva L3 puffstage 3-6    158 larva L3 puffstage 7-9    133 white prepupae new    122 white prepupae 12hr    110 white prepupae 24hr    119 pupae 2d postWPP    230 pupae 3d postWPP    652 pupae 4d postWPP    920 adult male 01day    926 adult male 05day    699 adult male 30day    291 adult female 01day    795 adult female 05day    338 adult female 30day    266 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (216) embryo 02-04hr  (301) embryo 04-06hr  (233) embryo 06-08hr  (152) embryo 08-10hr  (181) embryo 10-12hr  (301) embryo 12-14hr  (195) embryo 14-16hr  (261) embryo 16-18hr  (283) embryo 18-20hr  (385) embryo 20-22hr  (504) embryo 22-24hr  (503) larva L1  (615) larva L2  (643) larva L3 12hr old  (622) larva L3 puffstage 1-2  (317) larva L3 puffstage 3-6  (158) larva L3 puffstage 7-9  (133) white prepupae new  (122) white prepupae 12hr  (110) white prepupae 24hr  (119) pupae 2d postWPP  (230) pupae 3d postWPP  (652) pupae 4d postWPP  (920) adult male 01day  (926) adult male 05day  (699) adult male 30day  (291) adult female 01day  (795) adult female 05day  (338) adult female 30day  (266) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (216) embryo 02-04hr  (301) embryo 04-06hr  (233) embryo 06-08hr  (152) embryo 08-10hr  (181) embryo 10-12hr  (301) embryo 12-14hr  (195) embryo 14-16hr  (261) embryo 16-18hr  (283) embryo 18-20hr  (385) embryo 20-22hr  (504) embryo 22-24hr  (503) larva L1  (615) larva L2  (643) larva L3 12hr old  (622) larva L3 puffstage 1-2  (317) larva L3 puffstage 3-6  (158) larva L3 puffstage 7-9  133 white prepupae new  122 white prepupae 12hr  110 white prepupae 24hr  119 pupae 2d postWPP  (230) pupae 3d postWPP  (652) pupae 4d postWPP  (920) adult male 01day  (926) adult male 05day  (699) adult male 30day  (291) adult female 01day  (795) adult female 05day  (338) adult female 30day  (266) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    216 embryo 02-04hr    301 embryo 04-06hr    233 embryo 06-08hr    152 embryo 08-10hr    181 embryo 10-12hr    301 embryo 12-14hr    195 embryo 14-16hr    261 embryo 16-18hr    283 embryo 18-20hr    385 embryo 20-22hr    504 embryo 22-24hr    503 larva L1    615 larva L2    643 larva L3 12hr old    622 larva L3 puffstage 1-2    317 larva L3 puffstage 3-6    158 larva L3 puffstage 7-9    133 white prepupae new    122 white prepupae 12hr    110 white prepupae 24hr    119 pupae 2d postWPP    230 pupae 3d postWPP    652 pupae 4d postWPP    920 adult male 01day    926 adult male 05day    699 adult male 30day    291 adult female 01day    795 adult female 05day    338 adult female 30day    266 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    370 Schneider line 2 Sg4    368 embryonic 1182-4H    183 embryonic GM2    175 embryonic Kc167    137 embryonic S1    329 embryonic S3    275 leg disc CME L1    298 wing disc CME-W2    272 wing disc ML-DmD8    214 wing disc ML-DmD9    296 wing disc ML-DmD16-c3    195 wing disc ML-DmD21    453 wing disc ML-DmD32    254 haltere disc ML-DmD17-c3    359 eye-antennal disc ML-DmD11    569 antennal disc ML-DmD20-c5    443 mixed discs ML-DmD4-c1    244 CNS ML-DmBG1-c1    239 CNS ML-DmBG2-c2    186 tumorous blood cells mbn2    126 ovary fGS/OSS    182 ovary OSC    212 ovary OSS    152 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (370) Schneider line 2 Sg4  (368) embryonic 1182-4H  (183) embryonic GM2  (175) embryonic Kc167  (137) embryonic S1  (329) embryonic S3  (275) leg disc CME L1  (298) wing disc CME-W2  (272) wing disc ML-DmD8  (214) wing disc ML-DmD9  (296) wing disc ML-DmD16-c3  (195) wing disc ML-DmD21  (453) wing disc ML-DmD32  (254) haltere disc ML-DmD17-c3  (359) eye-antennal disc ML-DmD11  (569) antennal disc ML-DmD20-c5  (443) mixed discs ML-DmD4-c1  (244) CNS ML-DmBG1-c1  (239) CNS ML-DmBG2-c2  (186) tumorous blood cells mbn2  (126) ovary fGS/OSS  (182) ovary OSC  (212) ovary OSS  (152) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (370) Schneider line 2 Sg4  (368) embryonic 1182-4H  (183) embryonic GM2  (175) embryonic Kc167  (137) embryonic S1  (329) embryonic S3  (275) leg disc CME L1  (298) wing disc CME-W2  (272) wing disc ML-DmD8  (214) wing disc ML-DmD9  (296) wing disc ML-DmD16-c3  (195) wing disc ML-DmD21  (453) wing disc ML-DmD32  (254) haltere disc ML-DmD17-c3  (359) eye-antennal disc ML-DmD11  (569) antennal disc ML-DmD20-c5  (443) mixed discs ML-DmD4-c1  (244) CNS ML-DmBG1-c1  (239) CNS ML-DmBG2-c2  (186) tumorous blood cells mbn2  (126) ovary fGS/OSS  (182) ovary OSC  (212) ovary OSS  (152) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    370 Schneider line 2 Sg4    368 embryonic 1182-4H    183 embryonic GM2    175 embryonic Kc167    137 embryonic S1    329 embryonic S3    275 leg disc CME L1    298 wing disc CME-W2    272 wing disc ML-DmD8    214 wing disc ML-DmD9    296 wing disc ML-DmD16-c3    195 wing disc ML-DmD21    453 wing disc ML-DmD32    254 haltere disc ML-DmD17-c3    359 eye-antennal disc ML-DmD11    569 antennal disc ML-DmD20-c5    443 mixed discs ML-DmD4-c1    244 CNS ML-DmBG1-c1    239 CNS ML-DmBG2-c2    186 tumorous blood cells mbn2    126 ovary fGS/OSS    182 ovary OSC    212 ovary OSS    152 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    370 Schneider line 2 Sg4    368 embryonic 1182-4H    183 embryonic GM2    175 embryonic Kc167    137 embryonic S1    329 embryonic S3    275 leg disc CME L1    298 wing disc CME-W2    272 wing disc ML-DmD8    214 wing disc ML-DmD9    296 wing disc ML-DmD16-c3    195 wing disc ML-DmD21    453 wing disc ML-DmD32    254 haltere disc ML-DmD17-c3    359 eye-antennal disc ML-DmD11    569 antennal disc ML-DmD20-c5    443 mixed discs ML-DmD4-c1    244 CNS ML-DmBG1-c1    239 CNS ML-DmBG2-c2    186 tumorous blood cells mbn2    126 ovary fGS/OSS    182 ovary OSC    212 ovary OSS    152 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (370) Schneider line 2 Sg4  (368) embryonic 1182-4H  (183) embryonic GM2  (175) embryonic Kc167  (137) embryonic S1  (329) embryonic S3  (275) leg disc CME L1  (298) wing disc CME-W2  (272) wing disc ML-DmD8  (214) wing disc ML-DmD9  (296) wing disc ML-DmD16-c3  (195) wing disc ML-DmD21  (453) wing disc ML-DmD32  (254) haltere disc ML-DmD17-c3  (359) eye-antennal disc ML-DmD11  (569) antennal disc ML-DmD20-c5  (443) mixed discs ML-DmD4-c1  (244) CNS ML-DmBG1-c1  (239) CNS ML-DmBG2-c2  (186) tumorous blood cells mbn2  (126) ovary fGS/OSS  (182) ovary OSC  (212) ovary OSS  (152) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (370) Schneider line 2 Sg4  (368) embryonic 1182-4H  (183) embryonic GM2  (175) embryonic Kc167  137 embryonic S1  (329) embryonic S3  (275) leg disc CME L1  (298) wing disc CME-W2  (272) wing disc ML-DmD8  (214) wing disc ML-DmD9  (296) wing disc ML-DmD16-c3  (195) wing disc ML-DmD21  (453) wing disc ML-DmD32  (254) haltere disc ML-DmD17-c3  (359) eye-antennal disc ML-DmD11  (569) antennal disc ML-DmD20-c5  (443) mixed discs ML-DmD4-c1  (244) CNS ML-DmBG1-c1  (239) CNS ML-DmBG2-c2  (186) tumorous blood cells mbn2  126 ovary fGS/OSS  (182) ovary OSC  (212) ovary OSS  (152) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    370 Schneider line 2 Sg4    368 embryonic 1182-4H    183 embryonic GM2    175 embryonic Kc167    137 embryonic S1    329 embryonic S3    275 leg disc CME L1    298 wing disc CME-W2    272 wing disc ML-DmD8    214 wing disc ML-DmD9    296 wing disc ML-DmD16-c3    195 wing disc ML-DmD21    453 wing disc ML-DmD32    254 haltere disc ML-DmD17-c3    359 eye-antennal disc ML-DmD11    569 antennal disc ML-DmD20-c5    443 mixed discs ML-DmD4-c1    244 CNS ML-DmBG1-c1    239 CNS ML-DmBG2-c2    186 tumorous blood cells mbn2    126 ovary fGS/OSS    182 ovary OSC    212 ovary OSS    152 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    256 cold shock, 4-day adult    346 heat shock, 4-day adult    464 Cadmium 50 mM 6 hrs, larvae L3    628 Cadmium 50 mM 12 hrs, larvae L3    332 Cadmium 50 mM 48 hrs, 4-day adult    403 Cadmium 100 mM 48 hrs, 4-day adult    219 Copper 0.5 mM 12 hrs, larvae L3    341 Copper 15 mM 48 hrs, 4-day adult    199 Zinc 5 mM 12 hrs, larvae L3    418 Zinc 4.5 mM 48 hrs, 4-day adult    308 Ethanol 2.5% 3 hrs, larvae L3    372 Ethanol 5% 3 hrs, larvae L3    607 Ethanol 10% 3 hrs, larvae L3    617 Caffeine 1.5 mg/ml 4 hrs, larvae L3    459 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    227 Caffeine 25 mg/ml 48 hrs, 4-day adult    242 Paraquat 5 mM 48 hrs, 4-day adult    379 Paraquat 10 mM 48 hrs, 4-day adult    393 Rotenone 2 μg 12 hrs, larvae L3    631 Rotenone 8 μg 12 hrs, larvae L3    826 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (256) cold shock, 4-day adult  (346) heat shock, 4-day adult  (464) Cadmium 50 mM 6 hrs, larvae L3  (628) Cadmium 50 mM 12 hrs, larvae L3  (332) Cadmium 50 mM 48 hrs, 4-day adult  (403) Cadmium 100 mM 48 hrs, 4-day adult  (219) Copper 0.5 mM 12 hrs, larvae L3  (341) Copper 15 mM 48 hrs, 4-day adult  (199) Zinc 5 mM 12 hrs, larvae L3  (418) Zinc 4.5 mM 48 hrs, 4-day adult  (308) Ethanol 2.5% 3 hrs, larvae L3  (372) Ethanol 5% 3 hrs, larvae L3  (607) Ethanol 10% 3 hrs, larvae L3  (617) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (459) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (227) Caffeine 25 mg/ml 48 hrs, 4-day adult  (242) Paraquat 5 mM 48 hrs, 4-day adult  (379) Paraquat 10 mM 48 hrs, 4-day adult  (393) Rotenone 2 μg 12 hrs, larvae L3  (631) Rotenone 8 μg 12 hrs, larvae L3  (826) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (256) cold shock, 4-day adult  (346) heat shock, 4-day adult  (464) Cadmium 50 mM 6 hrs, larvae L3  (628) Cadmium 50 mM 12 hrs, larvae L3  (332) Cadmium 50 mM 48 hrs, 4-day adult  (403) Cadmium 100 mM 48 hrs, 4-day adult  (219) Copper 0.5 mM 12 hrs, larvae L3  (341) Copper 15 mM 48 hrs, 4-day adult  (199) Zinc 5 mM 12 hrs, larvae L3  (418) Zinc 4.5 mM 48 hrs, 4-day adult  (308) Ethanol 2.5% 3 hrs, larvae L3  (372) Ethanol 5% 3 hrs, larvae L3  (607) Ethanol 10% 3 hrs, larvae L3  (617) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (459) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (227) Caffeine 25 mg/ml 48 hrs, 4-day adult  (242) Paraquat 5 mM 48 hrs, 4-day adult  (379) Paraquat 10 mM 48 hrs, 4-day adult  (393) Rotenone 2 μg 12 hrs, larvae L3  (631) Rotenone 8 μg 12 hrs, larvae L3  (826) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    256 cold shock, 4-day adult    346 heat shock, 4-day adult    464 Cadmium 50 mM 6 hrs, larvae L3    628 Cadmium 50 mM 12 hrs, larvae L3    332 Cadmium 50 mM 48 hrs, 4-day adult    403 Cadmium 100 mM 48 hrs, 4-day adult    219 Copper 0.5 mM 12 hrs, larvae L3    341 Copper 15 mM 48 hrs, 4-day adult    199 Zinc 5 mM 12 hrs, larvae L3    418 Zinc 4.5 mM 48 hrs, 4-day adult    308 Ethanol 2.5% 3 hrs, larvae L3    372 Ethanol 5% 3 hrs, larvae L3    607 Ethanol 10% 3 hrs, larvae L3    617 Caffeine 1.5 mg/ml 4 hrs, larvae L3    459 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    227 Caffeine 25 mg/ml 48 hrs, 4-day adult    242 Paraquat 5 mM 48 hrs, 4-day adult    379 Paraquat 10 mM 48 hrs, 4-day adult    393 Rotenone 2 μg 12 hrs, larvae L3    631 Rotenone 8 μg 12 hrs, larvae L3    826 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    256 cold shock, 4-day adult    346 heat shock, 4-day adult    464 Cadmium 50 mM 6 hrs, larvae L3    628 Cadmium 50 mM 12 hrs, larvae L3    332 Cadmium 50 mM 48 hrs, 4-day adult    403 Cadmium 100 mM 48 hrs, 4-day adult    219 Copper 0.5 mM 12 hrs, larvae L3    341 Copper 15 mM 48 hrs, 4-day adult    199 Zinc 5 mM 12 hrs, larvae L3    418 Zinc 4.5 mM 48 hrs, 4-day adult    308 Ethanol 2.5% 3 hrs, larvae L3    372 Ethanol 5% 3 hrs, larvae L3    607 Ethanol 10% 3 hrs, larvae L3    617 Caffeine 1.5 mg/ml 4 hrs, larvae L3    459 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    227 Caffeine 25 mg/ml 48 hrs, 4-day adult    242 Paraquat 5 mM 48 hrs, 4-day adult    379 Paraquat 10 mM 48 hrs, 4-day adult    393 Rotenone 2 μg 12 hrs, larvae L3    631 Rotenone 8 μg 12 hrs, larvae L3    826 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (256) cold shock, 4-day adult  (346) heat shock, 4-day adult  (464) Cadmium 50 mM 6 hrs, larvae L3  (628) Cadmium 50 mM 12 hrs, larvae L3  (332) Cadmium 50 mM 48 hrs, 4-day adult  (403) Cadmium 100 mM 48 hrs, 4-day adult  (219) Copper 0.5 mM 12 hrs, larvae L3  (341) Copper 15 mM 48 hrs, 4-day adult  (199) Zinc 5 mM 12 hrs, larvae L3  (418) Zinc 4.5 mM 48 hrs, 4-day adult  (308) Ethanol 2.5% 3 hrs, larvae L3  (372) Ethanol 5% 3 hrs, larvae L3  (607) Ethanol 10% 3 hrs, larvae L3  (617) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (459) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (227) Caffeine 25 mg/ml 48 hrs, 4-day adult  (242) Paraquat 5 mM 48 hrs, 4-day adult  (379) Paraquat 10 mM 48 hrs, 4-day adult  (393) Rotenone 2 μg 12 hrs, larvae L3  (631) Rotenone 8 μg 12 hrs, larvae L3  (826) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (256) cold shock, 4-day adult  (346) heat shock, 4-day adult  (464) Cadmium 50 mM 6 hrs, larvae L3  (628) Cadmium 50 mM 12 hrs, larvae L3  (332) Cadmium 50 mM 48 hrs, 4-day adult  (403) Cadmium 100 mM 48 hrs, 4-day adult  (219) Copper 0.5 mM 12 hrs, larvae L3  (341) Copper 15 mM 48 hrs, 4-day adult  (199) Zinc 5 mM 12 hrs, larvae L3  (418) Zinc 4.5 mM 48 hrs, 4-day adult  (308) Ethanol 2.5% 3 hrs, larvae L3  (372) Ethanol 5% 3 hrs, larvae L3  (607) Ethanol 10% 3 hrs, larvae L3  (617) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (459) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (227) Caffeine 25 mg/ml 48 hrs, 4-day adult  (242) Paraquat 5 mM 48 hrs, 4-day adult  (379) Paraquat 10 mM 48 hrs, 4-day adult  (393) Rotenone 2 μg 12 hrs, larvae L3  (631) Rotenone 8 μg 12 hrs, larvae L3  (826) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    256 cold shock, 4-day adult    346 heat shock, 4-day adult    464 Cadmium 50 mM 6 hrs, larvae L3    628 Cadmium 50 mM 12 hrs, larvae L3    332 Cadmium 50 mM 48 hrs, 4-day adult    403 Cadmium 100 mM 48 hrs, 4-day adult    219 Copper 0.5 mM 12 hrs, larvae L3    341 Copper 15 mM 48 hrs, 4-day adult    199 Zinc 5 mM 12 hrs, larvae L3    418 Zinc 4.5 mM 48 hrs, 4-day adult    308 Ethanol 2.5% 3 hrs, larvae L3    372 Ethanol 5% 3 hrs, larvae L3    607 Ethanol 10% 3 hrs, larvae L3    617 Caffeine 1.5 mg/ml 4 hrs, larvae L3    459 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    227 Caffeine 25 mg/ml 48 hrs, 4-day adult    242 Paraquat 5 mM 48 hrs, 4-day adult    379 Paraquat 10 mM 48 hrs, 4-day adult    393 Rotenone 2 μg 12 hrs, larvae L3    631 Rotenone 8 μg 12 hrs, larvae L3    826 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_15 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • GH01760 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0016691 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4307-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Oscp Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 OscpGD4768 lethal | RU486 conditional, with Scer\GAL4da.Switch.PT OscpGD4768 Sterility Allele female sterile | RU486 conditional, with Scer\GAL4da.Switch.PT OscpGD4768 Other Phenotypes Allele developmental rate defective | RU486 conditional, with Scer\GAL4da.Switch.PT OscpGD4768 short lived | female | RU486 conditional, with Scer\GAL4da.Switch.PT OscpGD4768 short lived | male | RU486 conditional, with Scer\GAL4da.Switch.PT OscpGD4768 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Oscp Class Mutagen Stocks Known lesion OscpB532 1 -- OscpCPTI003171 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Oscp Class Mutagen Stocks Known lesion OscpGD4768 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes OscpGLC01454 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes OscpKK107798 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)E(mod)4-1P11 (Pai et al., 2004) Df(3R)Exel7323 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4768} NA P{KK107798} NA P{TRiP.GLC01454} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{5HPw+}OscpB532 NA PBac{754.P.FSVS-0}OscpCPTI003171 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
lipid particle inferred from direct assay (Beller et al., 2006, Cermelli et al., 2006) mitochondrion inferred from direct assay (Alonso et al., 2005)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
hydrogen-exporting ATPase activity, phosphorylative mechanism inferred from sequence or structural similarity with NCBI_gi:4502303 (FlyBase, 1992-) inferred from sequence or structural similarity with UniProtKB:P48047 (Sardiello et al., 2003.6.11) non-traceable author statement (Caggese, 1996.7.30, Swiss-Prot Project Members, 1999.12.15) proton-transporting ATP synthase activity, rotational mechanism inferred from electronic annotation with InterPro:IPR000711 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
ATP synthesis coupled proton transport inferred from electronic annotation with InterPro:IPR000711 (FlyBase Curators et al., 2004-) proton transport inferred from sequence or structural similarity with UniProtKB:P48047 (Sardiello et al., 2003.6.11)
Cellular Component
CV term Evidence References
mitochondrial proton-transporting ATP synthase, central stalk inferred from sequence or structural similarity with UniProtKB:P48047 (Sardiello et al., 2003.6.11)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Oscp - 14-3-3ζ anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - ATPsyn-Cf6 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - ATPsyn-b experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Oscp - ATPsyn-d anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - ATPsyn-β experimental knowledge based (Guruharsha et al., 2011) Oscp - ATPsyn-γ anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - Acon experimental knowledge based (Guruharsha et al., 2011) Oscp - Ada anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Arpc2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG10581 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG11857 experimental knowledge based (Guruharsha et al., 2011) Oscp - CG12617 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG13829 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Oscp - CG13887 experimental knowledge based (Guruharsha et al., 2011) Oscp - CG18765 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG31522 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - CG33145 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG3321 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - CG3523 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG4278 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG4692 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Oscp - CG6330 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG8195 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG8745 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CG9231 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - CoIV experimental knowledge based (Guruharsha et al., 2011) Oscp - Df31 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Dh44-R2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Elongin-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Gpdh experimental knowledge based (Guruharsha et al., 2011) Oscp - Hsc70-1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Jwa experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Oscp - Mf experimental knowledge based (Guruharsha et al., 2011) Oscp - Mlc2 experimental knowledge based (Guruharsha et al., 2011) Oscp - Ost48 experimental knowledge based (Guruharsha et al., 2011) Oscp - Rab11 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Rtnl1 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - Snap anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Tm2 experimental knowledge based (Guruharsha et al., 2011) Oscp - Trap1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - Tsp29Fb anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - blw anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - chic anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - fabp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - fax anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - fwe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - jagn experimental knowledge based (Guruharsha et al., 2011) Oscp - l(1)G0230 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Oscp - l(2)06225 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Oscp - porin experimental knowledge based (Guruharsha et al., 2011) Oscp - regucalcin anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - sun experimental knowledge based (Guruharsha et al., 2011) Oscp - up experimental knowledge based (Guruharsha et al., 2011) Oscp - wls anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Oscp - wupA experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Oscp allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66909 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0016691 DroID - A comprehensive database of gene and protein interactions. • FBgn0016691 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41845
Orthologs
OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG63FHH9 Dipteran inclusive ortholog search EOG6QFWPD Insect inclusive ortholog search EOG6C86PM Arthropod inclusive ortholog search EOG6ZW3T9 Metazoa inclusive ortholog search EOG65TRGR
Orthologs in Drosophila Species (EOG63FHH9)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Oscp     Drosophila simulans   Dsim\GD19002 Y   Drosophila sechellia   Dsec\GM24212 Y   Drosophila erecta   Dere\GG16904 Y   Drosophila yakuba   Dyak\GE24286 Y   Drosophila ananassae   Dana\GF11421 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18097 Y   Drosophila persimilis   Dper\GL12538 Y   Drosophila willistoni   Dwil\GK13792 Y   Drosophila virilis   Dvir\GJ23207 Y   Drosophila mojavensis   Dmoj\GI22923 Y   Drosophila grimshawi   Dgri\GH18853 Y
Orthologs in non-Drosophila Dipterans (EOG6QFWPD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010823   Anopheles gambiae Malaria mosquito  Agam\AGAP003599   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ019321
Orthologs in non-Dipteran Insects (EOG6C86PM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Oscp   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012131   Acromyrmex echinatior Panamanian leafcutter ant  Aech\atpH   Atta cephalotes Leafcutter ant  Acep\atpH   Camponotus floridanus Florida carpenter ant  Cflo\atpH   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL23061   Linepithema humile Argentine ant  Lhum\LH10739   Pogonomyrmex barbatus Red harvester ant  Pbar\PB25964   Solenopsis invicta Red fire ant  Sinv\SINV10069   Acyrthosiphon pisum Pea aphid  Apim\ACYPI000052   Bombyx mori Silkmoth  Bmor\BGIBMGA011504   Pediculus humanus Human body louse  Phum\PHUM490640   Tribolium castaneum Red flour beetle  Tcas\Oscp
Orthologs in non-Insect Arthropods (EOG6ZW3T9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_303877   Ixodes scapularis Deer tick  Isca\ISCW021200
Orthologs in non-Arthropod Metazoa (EOG65TRGR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\atp-3   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023911gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007960gn   Danio rerio Zebrafish  Drer\atp5o   Xenopus tropicalis Western clawed frog  Xtro\atp5o   Gallus gallus Domestic chicken  Ggal\ATP5O   Mus musculus House mouse  Mmus\Gm5436   Mus musculus House mouse  Mmus\Atp5o   Rattus norvegicus Norway rat  Rnor\Atp5o   Homo sapiens Human  Hsap\ENSG00000241837   Homo sapiens Human  Hsap\ENSG00000249209
Human Orthologs (2)
Gene OMIM HGNC Hsap\ENSG00000241837     Hsap\ENSG00000249209
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD19002 Drosophila sechellia Dsec\GM24212 Drosophila erecta Dere\GG16904 Drosophila yakuba Dyak\GE24286 Drosophila ananassae Dana\GF11421 Drosophila pseudoobscura pseudoobscura Dpse\GA18097 Drosophila persimilis Dper\GL12538 Drosophila willistoni Dwil\GK13792 Drosophila virilis Dvir\GJ23207 Drosophila mojavensis Dmoj\GI22923 Drosophila grimshawi Dgri\GH18853
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	43265 y1 sc* v1; P{TRiP.GLC01454}attP2 16241 y1 w1118; PBac{5HPw+}OscpB532
VDRC	v106753 P{KK107798}VIE-260B v12792 w1118; P{GD4768}v12792 v12794 w1118; P{GD4768}v12794
Genomic Clones ( 2 )
	BACR13A02 BACR32A03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 187 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT25705 GH01760
Other clones	DPiM_GH01760
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT22995 GH08713 GH16765 GH16845 GH17574 GH21808 GH22236 GH24759 GH26118 GH26733 GH27225 GH28820 GM04950 GM18588 GM18594 GM31501 LD21359 LD28502 LD42057 LD45881 LP05359 LP21288 RE03539 RE12151 RE25690 RE25885 RE27773 RE35535 RE37866 RE39446 RE40161 RE42007 RE44985 RE50201 RE50226 RE51685 RE52592 RE55983 RE60263 RE74874 RH01777 RH02268 RH05159 RH05511 RH06120 RH06177 RH06287 RH09671 RH11673 RH17253 RH18525 RH18663 RH18677 RH21237 RH22170 RH22772 RH22983 RH24924 RH24928 RH25536 RH25647 RH26003 RH27163 RH27891 RH28459 RH29839 RH31060 RH31063 RH31493 RH33533 RH33966 RH34118 RH35263 RH36245 RH36383 RH37130 RH37901 RH37976 RH39368 RH39527 RH41434 RH42707 RH43039 RH43247 RH43530 RH43842 RH44117 RH44432 RH44484 RH44817 RH50059 RH51777 RH52518 RH55329 RH58343 RH60196 RH60538 RH61461 RH66275 RH68687 RH69254 RH71977 RH72344 RH72461 SD02467 SD15202 SD18082
Other clones	69608 69643 282665 282893 527254 CK01.119C.H2 Dmel_dig_004419_0696_2513 Dmel_dig_004420_0605_2409 Dmel_dig_005379_0703_1051 Dmel_dig_010581_0675_0859 Dmel_dig_012680_0601_0440 Dmel_dig_016398_0593_3281 Dmel_dig_017767_0652_3235 Dmel_neb_009824_0145_1083 Dmel_neb_013449_0665_0857 EK091161 EK196552 EK308557 EN07553 ESG019a.E21_G02 ESG0110b.E21_G06 FGH110C03 FGH117D08 FGH126F09 FGM004G06 FGM206G03 FGM209G01 FGM212E02 FGM223E08 FGM226G08 FGM229H09 FGM301G06 FGM317G01 FGM319F05 FGM325F02 RH18502 RH19918 RH41869 RH61559 RP003032113 RP003041767 RP003043936 RP003048304 RP003064577 RP003067008 RP003082450 RP003088278 RP003088435 RP003115877 RP003140783 RP003161985 RP003172571 RP003181583 RP003185372 RP003201340 RP003205789 RP003230710 RP003259495 RP003276292 RP003281903 RP003297253 RP003315563 RP003327536 RP003385785 RP003391098 RP003437075 RP003516607 RP003544257 RP003553937 RP003595159 RP003614294 RP003647224 RP003660343 RP003667885 RP003670128 RP003674091 UT01816
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0016691 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41845
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079634 NM_169631 RefSeq (Proteins) • NP_524358 NP_731995 DDBJ / EMBL / GenBank • AAF55156 AAL13490 AAN13642 AI062534 AI513120 AY058261 BF489611 CAA67980 X99666 Entrez Gene - A searchable database of RefSeq genes. • 41845 UniProtKB/Swiss-Prot • Q24439 UniProtKB/TrEMBL • Q8INE6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ATPase, F1 complex, OSCP/delta subunit (IPR000711) F1F0 ATP synthase OSCP/delta subunit, N-terminal domain (IPR026015) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME04307 BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH01760
Linkouts
	BioGRID - A database of protein and genetic interactions • 66909 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0016691 DroID - A comprehensive database of gene and protein interactions. • FBgn0016691 DRSC - Results from RNAi screens. • FBgn0016691 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0016691 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4307-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0016691 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41845 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41845 modMine - Data generated by the modENCODE project. • FBgn0016691
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	ATPO_DROME (Storm and Sonnhammer, 2003) CG4307 (Cermelli et al., 2006, Porcelli et al., 2007, Keleman et al., 2009.8.5, Cammarato et al., 2011, Ni et al., 2010.12.1) OSCP (Caggese, 1996.7.30, Pai et al., 2004) Oscp (Beller et al., 2006, Cermelli et al., 2006, Tripoli et al., 2005, Xun et al., 2009, Rera et al., 2010, Wasbrough et al., 2010, Alonso et al., 2005, Malone et al., 2012)
Name Synonym	ATP synthase OSCP (Tripoli et al., 2005, Lemos et al., 2010) F0/F1 ATP synthase OSCP (Porcelli et al., 2007) Oligimycin sensitive-conferring protein (Cermelli et al., 2006) Oligomycin sensitivity-conferring protein (Xun et al., 2009, Cammarato et al., 2011) OLIGOMYCIN SENSITIVITY CONFERRING PROTEIN (Alonso et al., 2005)
Secondary FlyBase IDs
References ( 39 )
Generate a list of	All references relating to this gene ( 39 )
List References by type	Research paper  ( 13 ) Supplementary material  ( 9 ) Personal communication to FlyBase  ( 11 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Malone et al., 2012, Genome Biol. 13(4): r28 Mediation of Drosophila autosomal dosage effects and compensation by network interactions. [FBrf0219684] Show all research papers ...