A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Gene Ctet\TeTxLC

General Information
SymbolCtet\TeTxLCSpeciesC. tetani
NameTetanus toxin light chainAnnotation symbol
Feature typeengineered_foreign_geneFlyBase IDFBgn0016753
Gene Model StatusNot Applicable Stock availability 10 publicly available
Also Known AsTNT, TeTxLc, TeTx, tetanus toxin
Genomic Location
Chromosome (arm)Recombination map
Cytogenetic mapSequence location
hide Summary Information
Automatically generated summary

See sections below for more information
The gene Tetanus toxin light chain is referred to in FlyBase by the symbol Ctet\TeTxLC (FBgn0016753). It is a engineered_foreign_gene from Clostridium tetani. Its molecular function is unknown. The biological processes in which it is involved are not known. 12 alleles are reported. The phenotypes of these alleles are annotated with: nervous system; organ system subdivision; organ system; adult segment; embryonic/larval neuron; adult mesothoracic segment; multi-cell-component structure; peripheral nervous system; serotonergic neuron; indirect flight muscle. It has no annotated transcripts. Gene has not been localized to the genome sequence.
hide Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
hide Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term
References
hide Expression Deduced from Reporters
hide High-Throughput Expression Data
Associated Tools
Reference
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
hide FlyAtlas Anatomy Microarray
hide modENCODE Anatomy RNA-Seq
hide modENCODE Development RNA-Seq
hide modENCODE Cell Lines RNA-Seq
hide modENCODE Treatments RNA-Seq
hide Expression Clusters
hide External Data & Images
Linkouts
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
aCC neuron & neuromuscular junction, with Scer\GAL4eve.RRC
aCC neuron & synapse, with Scer\GAL4eve.RRC
antennal sense organ & neuron, with Scer\GAL4GH86
chemosensory sensory organ & neuron, with Scer\GAL4GH86
giant fibers & synapse, with Scer\GAL4c17
larval maxillary sense organ & neuron, with Scer\GAL4GH86
monopolar laminar cell & axon, with Scer\GAL4MZ1369
pharyngeal sense organ & neuron, with Scer\GAL4GH86
photoreceptor cell R7 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R7 & axon, with Scer\GAL4MZ1369
photoreceptor cell R8 & axon, with Scer\GAL4GMR.PF
photoreceptor cell R8 & axon, with Scer\GAL4MZ1369
synapse & aCC neuron, with Scer\GAL4eve.RRK
synapse & RP2 neuron, with Scer\GAL4eve.RRK
hide Classical Alleles ( 0 )
For All Classical Alleles Show

Allele of Ctet\TeTxLCClassMutagenStocksKnown lesion
hide Alleles Carried on Transgenic Constructs ( 12 )
For All Alleles Carried on Transgenic Constructs Show

Allele of Ctet\TeTxLCClassMutagenStocksKnown lesion
Ctet\TeTxLCTNT.Scer\UAS4 Yes
Ctet\TeTxLCIMPTNT-V.Scer\UAS2 Yes
Ctet\TeTxLCIMPTNT.Scer\FRT.Scer\UAS2 Yes
Ctet\TeTxLCIMPTNT-Q.Scer\UAS1 Yes
Ctet\TeTxLCScer\FRT.Scer\UAS1 Yes
Ctet\TeTxLCIMPTNT.Scer\UAS0 Yes
Ctet\TeTxLCin.Scer\FRT.stop.Scer\UAS0 Yes
Ctet\TeTxLCin.Scer\UAS0 Yes
Ctet\TeTxLCScer\FRT.stop.Scer\UAS0 Yes
Ctet\TeTxLCScer\UAS.cKa0 Yes
Ctet\TeTxLCScer\UAS.cSa0 Yes
Ctet\TeTxLCScer\UAS.cTa0 Yes
hide Aneuploid Aberrations
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
Insertions
Type of insertions
Name
Expression data
hide Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
hide Terms Based on Experimental Evidence ( 0 terms )
hide Terms Based on Predictions or Assertions ( 0 terms )
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
Ctet\TeTxLC allele
Gene
References
hide External Data
Linkouts
DroID - A comprehensive database of gene and protein interactions.
hide Orthologs
hide OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
Drosophila inclusive ortholog search
No orthologs identified
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Ortholog(s) in Drosophila melanogaster (None identified)
No D. melanogaster orthologies identified
hide Human Orthologs (0)
Gene
OMIM
HGNC
hideAAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 10 )
Bloomington
hide Genomic Clones ( 0 )
hide cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
hide Antibody Information
hide Other Information
hide Discoverer
hide Etymology
hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
hide Other Comments
Ctet\TeTxLC expressed in transgenic flies cleaves n-syb and abolishes synaptic transmission at a defined neuromuscular junction.
hide Tag or Foreign Gene Data
  • Foreign sequence; species == Clostridium tetani; gene == 'TeTxLC'; UniProt:P04958.
hide External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
DroID - A comprehensive database of gene and protein interactions.
hide Synonyms & Secondary IDs ( 20 )
Reported As
Symbol Synonym
Ctet\TeTxLC
 
Name Synonym
light chain of tetanus toxin
Tetanus neurotoxin light chain
Tetanus toxin light chain
 
Secondary FlyBase IDs
hide References ( 124 )
Generate a list of
List References by type
hide Recent research papers ( 14 )
Eddison et al., 2012, PLoS ONE 7(12): e51684
A genetic screen for olfactory habituation mutations in Drosophila: analysis of novel foraging alleles and an underlying neural circuit. [FBrf0220425]
Keleman et al., 2012, Nature 489(7414): 145--149
Dopamine neurons modulate pheromone responses in Drosophila courtship learning. [FBrf0219398]
Lu et al., 2012, PLoS Genet. 8(3): e1002587
ppk23-Dependent Chemosensory Functions Contribute to Courtship Behavior in Drosophila melanogaster. [FBrf0217844]
Rezaval et al., 2012, Curr. Biol. 22(13): 1155--1165
Neural circuitry underlying Drosophila female postmating behavioral responses. [FBrf0218941]
Sadaf et al., 2012, PLoS ONE 7(9): e46405
Synaptic Activity in Serotonergic Neurons Is Required for Air-Puff Stimulated Flight in Drosophila melanogaster. [FBrf0219558]
Thistle et al., 2012, Cell 149(5): 1140--1151
Contact Chemoreceptors Mediate Male-Male Repulsion and Male-Female Attraction during Drosophila Courtship. [FBrf0218411]
Tsubouchi et al., 2012, Curr. Biol. 22(22): 2124--2134
Dendritic Filopodia, Ripped Pocket, NOMPC, and NMDARs Contribute to the Sense of Touch in Drosophila Larvae. [FBrf0219946]
Bang et al., 2011, PLoS Genet. 7(3): e1001346
Dopamine signalling in mushroom bodies regulates temperature-preference behaviour in Drosophila. [FBrf0213392]
Chow et al., 2011, J. Neurosci. 31(42): 15035--15047
An olfactory circuit increases the fidelity of visual behavior. [FBrf0216480]
Crisp et al., 2011, J. Neurosci. 31(29): 10445--10450
Endogenous patterns of activity are required for the maturation of a motor network. [FBrf0214467]
Gallio et al., 2011, Cell 144(4): 614--624
The coding of temperature in the Drosophila brain. [FBrf0213085]
King et al., 2011, J. Neurosci. 31(3): 1139--1148
Drosophila tao Controls Mushroom Body Development and Ethanol-Stimulated Behavior through par-1. [FBrf0212818]
Lieber et al., 2011, Neuron 69(3): 468--481
DSL-Notch Signaling in the Drosophila Brain in Response to Olfactory Stimulation. [FBrf0212999]
von Philipsborn et al., 2011, Neuron 69(3): 509--522
Neuronal control of Drosophila courtship song. [FBrf0212984]
hide Recent reviews (0)
All reviews listed in FlyBase were published before 2011