Gene Dmel\fz2

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General Information

Symbol

Dmel\fz2

Species

D. melanogaster

Name

frizzled 2

Annotation symbol

CG9739

Feature type

protein_coding_gene

FlyBase ID

FBgn0016797

Gene Model Status

Current

Stock availability

32 publicly available

Also Known As

Dfz2, Dfrz2, fz-2, DFz-2, D-fz2, dfz2r

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

75F9-76A3

Sequence location

3L:19,134,075..19,228,473 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene frizzled 2 is referred to in FlyBase by the symbol Dmel\fz2 (CG9739, FBgn0016797). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: Wnt-activated receptor activity; PDZ domain binding; Wnt-protein binding. There is experimental evidence for 11 unique biological process terms, many of which group under: single-organism developmental process; cellular component organization or biogenesis; biological regulation; system development; cellular process; cellular component movement; localization; gland morphogenesis; post-embryonic organ morphogenesis; sensory organ development. 120 alleles are reported. The phenotypes of these alleles are annotated with: organ system; organ system subdivision; adult segment; external compound sense organ; synapse; peripheral nervous system; acellular anatomical structure; embryonic/larval neuron; postsynaptic membrane; embryonic foregut. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Frizzled domain; Frizzled protein; Frizzled-2; Frizzled/secreted frizzled-related protein; GPCR, family 2-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval fat body, larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass. Gene sequence location is 3L:19134075..19228473.

User Contributed Data

Beta version, feedback welcome

External Summaries

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

Controlled Vocabulary Terms

canonical Wnt receptor signaling pathway

cell projection

regulation of transcription from RNA polymerase II promoter

vasculature development

embryo development

brain development

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

75F9-76A3

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

76A-76A

(Bhanot, 1996.7.30)

Experimentally Determined Recombination Data

Location

(Bhanot, 1996.7.30)

Left of (cM)

(Chen and Struhl, 1999)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\fz2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.45

Gene model reviewed during 5.44

Gene model reviewed during 5.46

Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated

gene_with_stop_codon_read_through ; SO:0000697

Stop-codon suppression (UGA) postulated; FBrf0216884.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

fz2-RA

FBtr0075029

NM_079431

3673

694

fz2-RB

FBtr0075028

NM_168787

3839

694

fz2-RC

FBtr0112890

NM_001104173

5113

694

fz2-RD

FBtr0299586

NM_001144499

4580

694

fz2-RE

FBtr0330194

NM_001275107

4345

694

fz2-RF

FBtr0330195

NM_001275108

3839

806

fz2-RG

FBtr0332735

NM_001275109

5696

694

Additional Transcript Data & Comments

Reported size (kB)

5.5 (northern blot)

(Bhanot et al., 1996)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

fz2-PA

FBpp0074796

75.5

694

8.25

NP_524155

AAF49184

fz2-PB

FBpp0074795

75.5

694

8.25

NP_730389

AAF49185

fz2-PC

FBpp0111803

75.5

694

8.25

NP_001097643

ABW08569

fz2-PD

FBpp0288861

75.5

694

8.25

NP_001137971

ACL83326

fz2-PE

FBpp0303227

75.5

694

8.25

NP_001262036

AGB94729

fz2-PF

FBpp0303228

85.4

806

8.13

NP_001262037

AGB94730

fz2-PG

FBpp0304981

75.5

694

8.25

NP_001262038

AGB94731

Additional Polypeptide Data & Comments

Reported size (kDa)

694 (aa)

(Bhanot et al., 1996)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

GPCR, family 2-like (IPR017981)

Frizzled protein (IPR000539)

Frizzled/secreted frizzled-related protein (IPR015526)

Frizzled domain (IPR020067)

Frizzled-2 (IPR026550)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VVX3

UniProtKB/TrEMBL

B7Z072

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

regulatory region

FBsf0000435137
3L:19,139,780..19,140,051

evidence=Reporter construct (in vivo)

(Junion et al., 2005, Halfon, 2012.6.19)

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- adult stage

(Bhanot et al., 1996)

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

clypeo-labral anlage in statu nascendi

(Fisher et al., 2012)

dorsal ectoderm anlage

(Fisher et al., 2012)

Comment:anlage in statu nascendi

ectoderm anlage

(Fisher et al., 2012)

Comment:anlage in statu nascendi

mesoderm anlage

(Fisher et al., 2012)

Comment:anlage in statu nascendi

organism | gap expression pattern

(Fisher et al., 2012)

ventral ectoderm anlage

(Fisher et al., 2012)

Comment:anlage in statu nascendi

embryonic stage 6

organism | 10-70% egg length

(Bhanot et al., 1996)

Comment:~15-70% egg length

embryonic stage 7 -- 8

clypeo-labral anlage

(Fisher et al., 2012)

dorsal ectoderm

(Fisher et al., 2012)

ventral ectoderm

(Fisher et al., 2012)

embryonic stage 8

organism | segmentally repeated

(Bhanot et al., 1996)

embryonic stage 9 -- 10

clypeo-labral primordium

(Fisher et al., 2012)

dorsal ectoderm

(Fisher et al., 2012)

dorsal epidermis primordium

(Fisher et al., 2012)

Comment:reported as dorsal epidermis anlage

ventral ectoderm

(Fisher et al., 2012)

ventral epidermis primordium

(Fisher et al., 2012)

embryonic stage 9 -- 17

presumptive embryonic/larval central nervous system | presumptive

(Bhanot et al., 1996)

embryonic stage 10

procephalic neurogenic region

(Bhanot et al., 1996)

posterior midgut primordium

(Bhanot et al., 1996)

embryonic stage 11 -- 12

atrium | precursor

(Fisher et al., 2012)

Comment:reported as atrium primordium

clypeo-labral primordium

(Fisher et al., 2012)

dorsal epidermis primordium

(Fisher et al., 2012)

visceral muscle primordium

(Fisher et al., 2012)

embryonic stage 12 -- 16

visceral mesoderm

(Bhanot et al., 1996)

embryonic stage 13 -- 16

embryonic dorsal epidermis

(Fisher et al., 2012)

embryonic/larval visceral muscle

(Fisher et al., 2012)

labral segment

(Fisher et al., 2012)

embryonic stage 13 -- 17

embryonic/larval hindgut

(Bhanot et al., 1996)

embryonic stage 17

embryonic/larval dorsal vessel

(Bhanot et al., 1996)

Additional Descriptive Data

fz2 transcript is first detected in a stripe at about 15-70% egg length in stage 6 embryos. By stage 8, a segmental expression pattern is visible, and at stage 10, 15 stripes are discernible in the presumptive head, trunk, posterior midgut primordium, in a subset of the cells at the anterior midgut invagination site, and in the procephalic lobe. At stage 12, fz2 expression is strong in the midgut and visceral mesoderm. Starting at stage 9, fz2 is also expressed in the central nervous system (CNS). At the end of embryogenesis, fz2 transcript is present in the CNS, the dorsal vessel, and the hindgut. Northern analysis shows that fz2 transcript is expressed in all developmental stages, with the highest levels during embryogenesis and in late larval and pupal life.

(Bhanot et al., 1996)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 9 -- 17

presumptive embryonic/larval central nervous system | presumptive

(Bhanot et al., 1996)

embryonic stage 10

procephalic neurogenic region

(Bhanot et al., 1996)

posterior midgut primordium

(Bhanot et al., 1996)

embryonic stage 12 -- 16

visceral mesoderm

(Bhanot et al., 1996)

embryonic stage 13 -- 17

embryonic/larval hindgut

(Bhanot et al., 1996)

embryonic stage 17

embryonic/larval dorsal vessel

(Bhanot et al., 1996)

third instar larval stage

bouton | subset

(Packard et al., 2002)

Additional Descriptive Data

fz2 protein expression is not detectable by immunolocalization at stage 6 of embryogenesis, when fz2 transcript is first detected. The transcript and protein expression patterns coincide on and after stage 9/10 of embryogenesis. fz2 protein is expressed in the embryonic central nervous system starting at stage 9, and continuing through the rest of embryogenesis. At stage 10, the posterior midgut primordium, and at stages 12-16, the visceral mesoderm, also expresses fz2 protein.

(Bhanot et al., 1996)

fz2 protein was observed in glutamatergic type 1b synaptic boutons at the larval neuromuscular junction. The protein was observed both pre- and post-synaptically although it was enriched in post-synaptic areas and co-localized with dlg1 protein staining.

(Packard et al., 2002)

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

colocalizes_with
early endosome

inferred from direct assay

(Rives et al., 2006)

endocytic vesicle

inferred from direct assay

(Piddini et al., 2005)

colocalizes_with
late endosome

inferred from direct assay

(Rives et al., 2006)

plasma membrane

inferred from direct assay

(Rives et al., 2006)

Expression Deduced from Reporters

Reporter: P{lacW}SB227

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult abdominal segment | restricted

(Lawrence et al., 2002)

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval fat body, larval trachea. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult spermathecae, adult male accessory gland, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		34
central nervous system, larvae L3		47
central nervous system, pupae P8		52
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		49
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(34)
central nervous system, larvae L3		(47)
central nervous system, pupae P8		(52)
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		(49)
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		34
central nervous system, larvae L3		47
central nervous system, pupae P8		52
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		49
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		34
central nervous system, larvae L3		47
central nervous system, pupae P8		52
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		49
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		34
central nervous system, larvae L3		47
central nervous system, pupae P8		52
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		49
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(34)
central nervous system, larvae L3		(47)
central nervous system, pupae P8		(52)
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		(49)
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		34
central nervous system, larvae L3		47
central nervous system, pupae P8		52
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		49
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		34
central nervous system, larvae L3		47
central nervous system, pupae P8		52
head, virgin 1-day female		9
head, virgin 4-day female		9
head, virgin 20-day female		15
head, mated 1-day female		8
head, mated 4-day female		8
head, mated 20-day female		14
head, mated 1-day male		11
head, mated 4-day male		13
head, mated 20-day male		12
salivary gland, larvae L3 wandering		1
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		10
digestive system, 1-day adult		7
digestive system, 4-day adult		7
digestive system, 20-day adult		6
fat body, larvae L3 wandering		23
fat body, white prepupae		49
fat body, pupae P8		21
carcass, larvae L3 wandering		26
carcass, 1-day adult		4
carcass, 4-day adult		4
carcass, 20-day adult		5
ovary, virgin 4-day female		9
ovary, mated 4-day female		7
testis, mated 4-day male		3
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		50
embryo 06-08hr		63
embryo 08-10hr		68
embryo 10-12hr		68
embryo 12-14hr		57
embryo 14-16hr		45
embryo 16-18hr		36
embryo 18-20hr		27
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		29
white prepupae new		37
white prepupae 12hr		47
white prepupae 24hr		50
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		(50)
embryo 06-08hr		(63)
embryo 08-10hr		(68)
embryo 10-12hr		(68)
embryo 12-14hr		(57)
embryo 14-16hr		(45)
embryo 16-18hr		(36)
embryo 18-20hr		(27)
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		(29)
white prepupae new		(37)
white prepupae 12hr		(47)
white prepupae 24hr		(50)
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		50
embryo 06-08hr		63
embryo 08-10hr		68
embryo 10-12hr		68
embryo 12-14hr		57
embryo 14-16hr		45
embryo 16-18hr		36
embryo 18-20hr		27
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		29
white prepupae new		37
white prepupae 12hr		47
white prepupae 24hr		50
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		50
embryo 06-08hr		63
embryo 08-10hr		68
embryo 10-12hr		68
embryo 12-14hr		57
embryo 14-16hr		45
embryo 16-18hr		36
embryo 18-20hr		27
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		29
white prepupae new		37
white prepupae 12hr		47
white prepupae 24hr		50
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		50
embryo 06-08hr		63
embryo 08-10hr		68
embryo 10-12hr		68
embryo 12-14hr		57
embryo 14-16hr		45
embryo 16-18hr		36
embryo 18-20hr		27
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		29
white prepupae new		37
white prepupae 12hr		47
white prepupae 24hr		50
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		(50)
embryo 06-08hr		(63)
embryo 08-10hr		(68)
embryo 10-12hr		(68)
embryo 12-14hr		(57)
embryo 14-16hr		(45)
embryo 16-18hr		(36)
embryo 18-20hr		27
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		29
white prepupae new		(37)
white prepupae 12hr		(47)
white prepupae 24hr		(50)
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		50
embryo 06-08hr		63
embryo 08-10hr		68
embryo 10-12hr		68
embryo 12-14hr		57
embryo 14-16hr		45
embryo 16-18hr		36
embryo 18-20hr		27
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		29
white prepupae new		37
white prepupae 12hr		47
white prepupae 24hr		50
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		3
embryo 02-04hr		19
embryo 04-06hr		50
embryo 06-08hr		63
embryo 08-10hr		68
embryo 10-12hr		68
embryo 12-14hr		57
embryo 14-16hr		45
embryo 16-18hr		36
embryo 18-20hr		27
embryo 20-22hr		20
embryo 22-24hr		22
larva L1		15
larva L2		9
larva L3 12hr old		6
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		21
larva L3 puffstage 7-9		29
white prepupae new		37
white prepupae 12hr		47
white prepupae 24hr		50
pupae 2d postWPP		25
pupae 3d postWPP		13
pupae 4d postWPP		6
adult male 01day		7
adult male 05day		6
adult male 30day		4
adult female 01day		6
adult female 05day		3
adult female 30day		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		31
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		(31)
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		31
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		31
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		31
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		31
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		31
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		4
Schneider line 2 Sg4		1
embryonic 1182-4H		3
embryonic GM2		4
embryonic Kc167		1
embryonic S1		1
embryonic S3		1
leg disc CME L1		1
wing disc CME-W2		0
wing disc ML-DmD8		31
wing disc ML-DmD9		1
wing disc ML-DmD16-c3		20
wing disc ML-DmD21		1
wing disc ML-DmD32		1
haltere disc ML-DmD17-c3		1
eye-antennal disc ML-DmD11		0
antennal disc ML-DmD20-c5		1
mixed discs ML-DmD4-c1		9
CNS ML-DmBG1-c1		1
CNS ML-DmBG2-c2		2
tumorous blood cells mbn2		1
ovary fGS/OSS		8
ovary OSC		12
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		8
cold shock, 4-day adult		8
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		6
Cadmium 50 mM 12 hrs, larvae L3		6
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		5
Copper 15 mM 48 hrs, 4-day adult		7
Zinc 5 mM 12 hrs, larvae L3		5
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		6
Ethanol 10% 3 hrs, larvae L3		4
Caffeine 1.5 mg/ml 4 hrs, larvae L3		6
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		6
Caffeine 25 mg/ml 48 hrs, 4-day adult		6
Paraquat 5 mM 48 hrs, 4-day adult		6
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		5
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

LD10629

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0016797

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CT33672;CG9739-RB;S.C3L002407

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal | pupal stage | heat sensitive, with Scer\GAL4^h-1J3

fz2^Scer\UAS.cCa

partially lethal - majority die

fz2^CB02997

viable

fz2^C1

viable, with Scer\GAL4^pnr-MD237

fz2^GD2719

Sterility

Allele

sterile

fz2^C1

Other Phenotypes

Allele

decreased cell death | pupal stage, with Scer\GAL4^GMR.PF

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

neuroanatomy defective

fz2^C1

neuroanatomy defective, with Scer\GAL4^C57

fz2^{C.Scer\UAS.NLS.T:Hsap\MYC}

neuroanatomy defective, with Scer\GAL4^GMR.PF

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

neuroanatomy defective | third instar larval stage, with Scer\GAL4^Mhc.PU

fz2^Scer\UAS.N

planar polarity defective, with Scer\GAL4^hs.2sev

fz2^Scer\UAS.N

small body

fz2^C1

visible, with Scer\GAL4^69B

visible, with Scer\GAL4^71B

visible, with Scer\GAL4^bbg-C96

visible, with Scer\GAL4^Bx-MS1096

fz2^Scer\UAS.cCa

visible, with Scer\GAL4^C-765

fz2^Scer\UAS.cSa

visible, with Scer\GAL4^h-1J3

fz2^Scer\UAS.cCa

visible, with Scer\GAL4^unspecified

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

Phenotype manifest in

Allele

axon & dorsal cluster neuron

fz2^C1

bouton, with Scer\GAL4^C57

chaeta | ectopic & wing, with Scer\GAL4^bbg-C96

fz2^Scer\UAS.cCa

crystal cell | third instar larval stage, with Scer\GAL4^lz-gal4

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

denticle row 1, with Scer\GAL4^en-e16E

fz2^Scer\UAS.cZa

dorsal denticle, with Scer\GAL4^da.G32

embryonic/larval lymph gland | third instar larval stage, with Scer\GAL4^Antp-10

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

embryonic epidermis | dorsal, with Scer\GAL4^da.G32

eye, with Scer\GAL4^hs.2sev

fz2^Scer\UAS.N

eye photoreceptor cell

fz2^C1

eye photoreceptor cell, with Scer\GAL4^GMR.PF

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

eye photoreceptor cell | P-stage, with Scer\GAL4^GMR.PF

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

interfollicle cell | supernumerary | heat sensitive, with Scer\GAL4^hs.PB

fz2^Scer\UAS.cCa

lamina

fz2^C1

lamina, with Scer\GAL4^GMR.PF

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

lymph gland derived hemocyte | third instar larval stage, with Scer\GAL4^dome-PG14

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

macrochaeta | ectopic, with Scer\GAL4^69B

mitochondrion & bouton, with Scer\GAL4^C57

fz2^Scer\UAS.cCa

morphogenetic furrow | ectopic, with Scer\GAL4^dpp.blk1

fz2^Scer\UAS.N

neuromuscular junction, with Scer\GAL4^C57

neuromuscular junction | third instar larval stage, with Scer\GAL4^Mhc.PU

fz2^Scer\UAS.N

neuron

fz2^C1

neuron, with Scer\GAL4^GMR.PF

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

NMJ bouton (with Df(3L)ED4782)

fz2^C1

ommatidium, with Scer\GAL4^hs.2sev

fz2^Scer\UAS.N

ovary

fz2^C1

postsynaptic membrane, with Scer\GAL4^C57

fz2^Scer\UAS.cCa

presumptive embryonic salivary gland, with Scer\GAL4^fkh.PZ

fz2^Scer\UAS.N

RP2 motor neuron, with Scer\GAL4^da.G32

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

RP2 motor neuron, with Scer\GAL4^hs.PB

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

t-bar, with Scer\GAL4^C57

fz2^Scer\UAS.cCa

wing, with Scer\GAL4^69B

wing, with Scer\GAL4^71B

wing, with Scer\GAL4^bbg-C96

wing, with Scer\GAL4^Bx-MS1096

fz2^Scer\UAS.cCa

wing, with Scer\GAL4^C-765

fz2^Scer\UAS.cSa

wing, with Scer\GAL4^h-1J3

fz2^Scer\UAS.cCa

wing, with Scer\GAL4^nub-AC-62

fz2^{GPI.Scer\UAS.T:Hsap\MYC}

wing, with Scer\GAL4^sd-SG29.1

fz2^Scer\UAS.N

wing, with Scer\GAL4^unspecified

fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}

wing & macrochaeta, with Scer\GAL4^69B

wing margin, with Scer\GAL4^69B

fz2^Scer\UAS.N

wing margin, with Scer\GAL4^dpp.blk1

fz2^Scer\UAS.N

wing margin, with Scer\GAL4^sd-SG29.1

fz2^Scer\UAS.N

wing margin bristle, with Scer\GAL4^bbg-C96

fz2^Scer\UAS.N

wing margin bristle, with Scer\GAL4^nub-AC-62

fz2^{GPI.Scer\UAS.T:Hsap\MYC}

wing margin bristle | ectopic, with Scer\GAL4^71B

wing margin bristle | ectopic, with Scer\GAL4^Bx-MS1096

wing margin bristle | ectopic, with Scer\GAL4^C-765

fz2^Scer\UAS.cSa

wing margin bristle | ectopic, with Scer\GAL4^dpp.blk1

fz2^{2-2-2.Scer\UAS.T:Hsap\MYC}

wing margin bristle | ectopic, with Scer\GAL4^unspecified

fz2^{Scer\UAS.cTa.T:Hsap\MYC}

wing sensillum | ectopic, with Scer\GAL4^69B

wing sensillum | ectopic, with Scer\GAL4^71B

fz2^Scer\UAS.cCa

wing sensillum | ectopic, with Scer\GAL4^h-1J3

fz2^Scer\UAS.cCa

Classical Alleles ( 49 )

For All Classical Alleles Show

Allele of fz2	Class	Mutagen	Stocks	Known lesion
fz2²⁸			1	--
fz2^5-HA-5054			1	--
fz2^BG01711			1	--
fz2^c00222b			1	--
fz2^c00231			1	--
fz2^c02449			1	--
fz2^CB-5135-3			1	--
fz2^CB-6363-3			1	--
fz2^d00607			1	--
fz2^d04722			1	--
fz2^d06927			1	--
fz2^e03835			1	--
fz2^EY02025			1	--
fz2^f01018		piggyBac transposase	1	--
fz2^f01076			1	--
fz2^f05937			1	--
fz2^f07590		piggyBac transposase	1	--
fz2^KG05823			1	--
fz2^KG06738			1	--
fz2^MB01455			1	--
fz2^MI01509			1	--
fz2^MI02902			1	--
fz2^MI04504			1	--
fz2^NP3337			1	--
fz2^UM-8378-3			1	--
fz2⁴⁶⁹		P-element activity	0	Yes
fz2^c01104			0	--
fz2^C1	loss of function allele	ethyl methanesulfonate	0	Yes
fz2^{C2.Scer\UAS.T:SS-wg,T:Ivir\HA1}			0	Yes
fz2^C2		ethyl methanesulfonate	0	Yes
fz2^{C3.Scer\UAS.T:SS-wg,T:Ivir\HA1}			0	Yes
fz2^C3		ethyl methanesulfonate	0	Yes
fz2^C4		ethyl methanesulfonate	0	Yes
fz2^CB02997		P-element activity	0	Yes
fz2^CPTI003490		piggyBac transposase	0	Yes
fz2^CRD			0	--
fz2^d04580			0	--
fz2^d10423			0	--
fz2^e1		ethyl methanesulfonate	0	Yes
fz2^e2		ethyl methanesulfonate	0	Yes
fz2^e3		ethyl methanesulfonate	0	Yes
fz2^e4		ethyl methanesulfonate	0	Yes
fz2^e5		ethyl methanesulfonate	0	Yes
fz2^e6		ethyl methanesulfonate	0	Yes
fz2^EP3012			0	--
fz2^EP3667			0	--
fz2^M2-8			0	--
fz2^MI07226			0	--
fz2^unspecified			0	--

Alleles Carried on Transgenic Constructs ( 71 )

For All Alleles Carried on Transgenic Constructs Show

Allele of fz2	Class	Mutagen	Stocks	Known lesion
fz2^{2-2-2.Scer\UAS.T:Hsap\MYC}		in vitro construct - coding region fusion in vitro construct - regulatory fusion	2	Yes
fz2^GD2719		in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
fz2^JF01259		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
fz2^JF01378		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
fz2^JF02722		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
fz2^{2-2-2.hs.2sev}		FLPase	0	Yes
fz2^{2-2-2.Scer\FRT.hs.2sev}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^{2-2-2.Scer\FRT.αTub84B}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^2-2-2.tub.W		in vitro construct - regulatory fusion	0	Yes
fz2^{2-2-2.αTub84B}		FLPase	0	Yes
fz2^{616.Act5c.T:Hsap\MYC}		in vitro construct - regulatory fusion	0	--
fz2^{616.Act5C.T:Hsap\MYC}		in vitro construct - coding region fusion	0	Yes
fz2^916-2204		in vitro construct - RNAi	0	Yes
fz2^916-922		in vitro construct - RNAi	0	Yes
fz2^a.916-2204		in vitro construct - RNAi	0	Yes
fz2^a.916-922		in vitro construct - RNAi	0	Yes
fz2^a.L.cKa		in vitro construct - RNAi	0	Yes
fz2^Act5C.PM		in vitro construct - regulatory fusion	0	Yes
fz2^Act5C.PS		in vitro construct - regulatory fusion	0	Yes
fz2^{Act5C.T:Ivir\HA1}		in vitro construct - regulatory fusion	0	Yes
fz2^C.Act5C		in vitro construct - regulatory fusion	0	Yes
fz2^{C.Scer\UAS.NLS.T:Hsap\MYC}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^C1.Scer\UAS		FLPase	0	Yes
fz2^{C2.Scer\UAS.T:Avic\GFP}		in vitro construct - site directed mutagenesis	0	Yes
fz2^{C3.Scer\UAS.T:Avic\GFP}		in vitro construct - site directed mutagenesis	0	Yes
fz2^{Cterm.Act5C.T:Avic\GFP}		in vitro construct - coding region fusion	0	Yes
fz2^{dsRNA.A.5'UTR}		in vitro construct - RNAi	0	Yes
fz2^dsRNA.cFa		in vitro construct - RNAi	0	Yes
fz2^dsRNA.cLa		in vitro construct - RNAi	0	Yes
fz2^dsRNA.cMa		in vitro construct - RNAi	0	--
fz2^{ECD.GPI.Scer\UAS.T:Hsap\MYC}		in vitro construct - coding region fusion in vitro construct - regulatory fusion	0	Yes
fz2^{GPI.Scer\UAS.T:Hsap\MYC}	antimorphic allele - genetic evidence	in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^{GSG15.αTub84B}		in vitro construct	0	Yes
fz2^{GSG18.αTub84B}		in vitro construct	0	Yes
fz2^hs.PW		in vitro construct - regulatory fusion	0	Yes
fz2^{hs.T:Ivir\HA1}		in vitro construct - coding region fusion	0	Yes
fz2^{hs.T:Zzzz\FLAG}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^KK108242		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
fz2^L.cKa		in vitro construct - RNAi	0	Yes
fz2^MtnA.PB		in vitro construct - regulatory fusion	0	Yes
fz2^MtnA.PR		in vitro construct - regulatory fusion	0	Yes
fz2^{MtnA.T:Zzzz\FLAG}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^N.Act5C		in vitro construct - regulatory fusion	0	Yes
fz2^NIG.9739R		in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
fz2^{Scer\FRT.Avic\GFP.y.Scer\UAS}		in vitro construct - regulatory fusion	0	Yes
fz2^{Scer\FRT.Rnor\CD2.y.Scer\UAS.C1}		in vitro construct - regulatory fusion	0	Yes
fz2^{Scer\FRT.Rnor\CD2.y.αTub84B}		in vitro construct - regulatory fusion	0	Yes
fz2^{Scer\UAS.6x.T:Hsap\MYC}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^Scer\UAS.cBa		in vitro construct - regulatory fusion	0	Yes
fz2^Scer\UAS.cCa		in vitro construct - regulatory fusion	0	Yes
fz2^Scer\UAS.cCb		FLPase	0	Yes
fz2^Scer\UAS.cPb		in vitro construct - regulatory fusion	0	Yes
fz2^Scer\UAS.cSa		in vitro construct - regulatory fusion	0	Yes
fz2^{Scer\UAS.cTa.T:Hsap\MYC}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^Scer\UAS.cZa		in vitro construct - regulatory fusion	0	Yes
fz2^Scer\UAS.N		in vitro construct	0	Yes
fz2^{Scer\UAS.Scer\FRT.T:Avic\GFP-ECFP}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^{Scer\UAS.T:Avic\GFP-ECFP}		FLPase	0	Yes
fz2^{Scer\UAS.T:Avic\GFP}		in vitro construct - coding region fusion in vitro construct - regulatory fusion	0	Yes
fz2^{Scer\UAS.T:Hsap\MYC}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^{Scer\UAS.T:SS-wg,T:Ivir\HA1}		in vitro construct - coding region fusion	0	Yes
fz2^{Scer\UAS.T:Zzzz\FLAG}		in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
fz2^αTub84B.PC	wild-type allele	FLPase	0	Yes
fz2^{ΔC.Scer\UAS.T:Hsap\MYC}		in vitro construct - regulatory fusion in vitro construct - deletion	0	Yes
fz2^{ΔC.Scer\UAS.T:Zzzz\FLAG}		in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - deletion	0	Yes
fz2^{ΔCRD.Scer\UAS}		in vitro construct - regulatory fusion in vitro construct - deletion	0	Yes
fz2^{ΔCRD.αTub84B.T:SS-wg,T:Ivir\HA1}		in vitro construct - coding region fusion	0	Yes
fz2^{ΔKTLES.Act5C}		in vitro construct - regulatory fusion in vitro construct - deletion	0	Yes
fz2^{ΔSGKTLESW.Act5C}		in vitro construct - regulatory fusion in vitro construct - deletion	0	Yes
fz2^{ΔSGKTLESW.Scer\UAS.T:Hsap\MYC}		in vitro construct - regulatory fusion in vitro construct - deletion	0	Yes
fz2^{ΔVWIWSG.Act5C}		in vitro construct - regulatory fusion in vitro construct - site directed mutagenesis	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3L)469-6

(Wharton, 2008.8.25)

Df(3L)469-13

(Wharton, 2008.8.25)

Df(3L)fz2

(Bhanot et al., 1999)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{UAS(FRT.w^GMR)fz2::ECFP}

P{UAS(FRT.y⁺CD2)fz2^C1}

P{UAS(FRT.y⁺GFP)fz2.C}

P{UAS(-FRT)fz2::EGFP}

reporter construct

heat-shock construct

P{hs.2sev(FRT.w^GMR)fz2.2-2-2}

P{hs.2sev(-FRT)fz2.2-2-2}

P{hs-fz2.FLAG}

characterization construct

P{hs.2sev(FRT.w^GMR)fz::fz2.1-1-2}

P{hs.2sev(FRT.w^GMR)fz::fz2.1-2-1}

P{hs.2sev(FRT.w^GMR)fz::fz2.1-2-2}

P{hs.2sev(FRT.w^GMR)fz::fz2.2-1-1}

P{hs.2sev(FRT.w^GMR)fz::fz2.2-2-1}

P{hs.2sev(-FRT)fz::fz2.1-1-2}

P{hs.2sev(-FRT)fz::fz2.1-2-1}

P{hs.2sev(-FRT)fz::fz2.1-2-2}

P{hs.2sev(-FRT)fz::fz2.2-1-1}

P{hs.2sev(-FRT)fz::fz2.2-2-1}

P{tub-fz::fz2.2-1-1.MYC}

P{UAS-fz2::otk.intra}

P{UAS-fz2:arr.intra.MYC}

P{αTub84B(FRT.w^GMR)fz2.2-2-2}

P{αTub84B(FRT.w^GMR)fz::fz2.1-1-2}

P{αTub84B(FRT.w^GMR)fz::fz2.1-2-1}

P{αTub84B(FRT.w^GMR)fz::fz2.1-2-2}

P{αTub84B(FRT.w^GMR)fz::fz2.2-1-1}

P{αTub84B(FRT.w^GMR)fz::fz2.2-2-1}

P{αTub84B(FRT.y⁺CD2)fz2.C}

P{αTub84B(-FRT)fz2.2-2-2}

P{αTub84B(-FRT)fz2.C}

P{αTub84B(-FRT)fz::fz2.1-1-2}

P{αTub84B(-FRT)fz::fz2.1-2-1}

P{αTub84B(-FRT)fz::fz2.1-2-2}

P{αTub84B(-FRT)fz::fz2.2-1-1}

P{αTub84B(-FRT)fz::fz2.2-2-1}

P{αTub84B-fz2.GSG15}

P{αTub84B-fz2.GSG18}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EP}fz2^EP3012

P{EP}fz2^EP3667

P{EPgy2}fz2^EY02025

P{Mae-UAS.6.11}B0326^B0326

P{Mae-UAS.6.11}B1365^B1365

P{Mae-UAS.6.11}B1521^B1521

miscellaneous insertions

insertion of enhancer trap binary system

Mi{ET1}fz2^MB01455

P{GawB}fz2^NP3337

Gene Ontology: Function, Process & Cellular Component ( 27 unique terms )

Terms Based on Experimental Evidence ( 18 terms )

Molecular Function

CV term

Evidence

References

PDZ domain binding

inferred from physical interaction with Grip

(Ataman et al., 2006)

Wnt-activated receptor activity

inferred from direct assay

(Rives et al., 2006, Bhanot et al., 1996)

Wnt-protein binding

inferred from direct assay

(assigned by UniProtKB)

(Bhanot et al., 1996)

inferred from physical interaction with wg

(Piddini et al., 2005)

inferred from physical interaction with wg, Wnt2, Wnt4

(Wu and Nusse, 2002)

Biological Process

CV term

Evidence

References

axon extension