Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping P1\cre using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView P1\cre in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In the presence of a P1\cre transgene driven by a dual Hsp70-Dmau\mariner\T promoter, a w reporter gene flanked by P1\loxP sites is excised with virtually 100% efficiency both in somatic and germ cells. A strong maternal effect, resulting from P1\cre recombinase present in the oocyte, is observed as white or mosaic eye colour in F1 progeny. Excision in germ cells of the F1 yields a strong grand-maternal effect, observed as a highly skewed ratio of eye-colour phenotypes in the F2 generation. The excision reactions of P1\cre/P1\loxP and the related Scer\FLP1/Scer\FRT system are used to create lines in which transgenes are at exactly allelic sites in homologous chromosomes.