FlyBase Gene Report: Dmel\Rca1

General Information

Symbol

Dmel\Rca1

Species

D. melanogaster

Name

Regulator of cyclin A1

Annotation Symbol

CG10800

Feature Type

protein_coding_gene

FlyBase ID

FBgn0017551

Gene Model Status

Current

Stock Availability

14 publicly available

Gene Snapshot

Regulator of cyclin A1 (Rca1) encodes an anaphase-promoting complex/cyclosome inhibitor. It contributes to mitotic G1/S transition and cyclin degradation. [Date last reviewed: 2019-07-11]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Emi1

Key Links

Genomic Location

Cytogenetic map

27C1-27C1

Sequence location

2L:6,852,315..6,853,866 [+]

Recombination map

2-23

RefSeq locus

NT_033779 REGION:6852315..6853866

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (5 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

involved_in G1/S transition of mitotic cell cycle

inferred from mutant phenotype

(Zielke et al., 2006)

involved_in negative regulation of ubiquitin protein ligase activity

inferred from mutant phenotype

(Zielke et al., 2006, Grosskortenhaus and Sprenger, 2002)

inferred from genetic interaction with FLYBASE:fzr; FB:FBgn0262699

(Grosskortenhaus and Sprenger, 2002)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in negative regulation of meiotic nuclear division

inferred from biological aspect of ancestor with PANTHER:PTN000398158

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in regulation of mitotic nuclear division

inferred from biological aspect of ancestor with PANTHER:PTN000398158

(assigned by GO_Central )

(Gaudet et al., 2011)

traceable author statement

(Lee and Orr-Weaver, 2003)

involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

inferred from sequence model

(FlyBase Curators, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in nucleus

inferred from direct assay

(Grosskortenhaus and Sprenger, 2002)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000398158

(assigned by GO_Central )

(Gaudet et al., 2011)

part_of SCF ubiquitin ligase complex

inferred from sequence model

(FlyBase Curators, 2011-)

Gene Group (FlyBase)

F BOX ONLY PROTEINS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

F BOX ONLY PROTEINS -: F box only proteins (FBXO) are F box proteins which do not contain WD40 repeats or leucine-rich repeats, but may contain other domains. F box proteins are the variable substrate adapters for Skp, Cullin, F-box (SCF) E3 ubiquitin ligase complexes. (Adapted from FBrf0225076).

Summary (Interactive Fly)

a novel signaling protein that prevents cyclin degredation in G2 by interacting with Fizzy-related - inhibits Fizzy-related's activation of protein degradation machinery - mutants exhibit premature cyclin destruction

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Rca1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.52

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Rca1-RA

FBtr0079342

NM_057866

1552

411

Additional Transcript Data and Comments

Reported size (kB)

1.577 (longest cDNA)

(Dong et al., 1997)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Rca1-PA

FBpp0078970

46.7

411

10.19

NP_477214

AAF52448

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

412 (aa)

(Dong et al., 1997)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rca1 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Rca1_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 8 -- 17

posterior midgut primordium

(Dong et al., 1997)

anterior midgut primordium

(Dong et al., 1997)

embryonic stage 13 -- 17

presumptive embryonic/larval nervous system

(Dong et al., 1997)

embryonic stage 8 -- 9

mesoderm

(Dong et al., 1997)

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

head mesoderm

(Fisher et al., 2012)

organism | faint | ubiquitous

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 11 -- 12

central brain primordium

(Fisher et al., 2012)

organism | faint | ubiquitous

(Fisher et al., 2012)

ventral nerve cord primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

embryonic/larval nervous system

(Fisher et al., 2012)

ventral nerve cord

(Fisher et al., 2012)

embryonic stage 2

organism | ubiquitous

(Dong et al., 1997)

Additional Descriptive Data

Rca1 transcripts are abundant and uniformly distributed in early embryos prior to cellularization. During germ band elongation in stages 8 and 9, transcripts are detected predominantly in the mesoderm and in the anterior and posterior midgut primordia. In stages 10 and 11, high levels of Rca1 transcript are observed throughout the embryo but not in the amnioserosa. By stage 13, staining is mainly restricted to the cells of the developing CNS. Weak expression is also observed in the midgut

(Dong et al., 1997)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in nucleus

inferred from direct assay

(Grosskortenhaus and Sprenger, 2002)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Rca1 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Rca1

View exonic expression by tissue for Dmel\Rca1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0017551

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0017551

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG10800-RA

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10800

Flygut - An atlas of the Drosophila adult midgut

FBgn0017551

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Rca1

Stages(s) 1-3
Stages(s) 7-8
Stages(s) 9-10
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 14 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 19 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Rca1

Transgenic constructs containing regulatory region of Rca1

Deletions and Duplications ( 5 )

Disrupted in

Df(2L)Dwee1

(BDGP Project Members, 1994-1999)

Df(2L)Dwee-δ5

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Not disrupted in

Df(2L)Dwee1-W05

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2L)J-H

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2L)spd

(BDGP Project Members, 1994-1999)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal

Rca1^GD12609

lethal | recessive

Rca1⁰³³⁰⁰

lethal - all die before end of pupal stage, with Scer\GAL4^arm.PS

Rca1^UAS.Tag:HA

lethal - all die during P-stage, with Scer\GAL4^Mef2.PR

Rca1^GD12609

partially lethal - majority die

Rca1⁰³³⁰⁰

viable

Rca1^e02614

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Rca1^GD12609

viable, with Scer\GAL4^pnr-MD237

Rca1^GD12609

viable, with Scer\GAL4^prd.RG1

Rca1^UAS.Tag:HA

Sterility

Allele

fertile

Rca1^e02614

Other Phenotypes

Allele

decreased cell number | embryonic cycle 16

Rca1²

decreased cell number | embryonic stage

Rca1²

decreased cell number | embryonic stage | somatic clone

Rca1²

decreased occurrence of cell division | embryonic stage

Rca1²

decreased occurrence of cell division | embryonic stage (with Rca1²)

Rca1³

decreased occurrence of cell division | embryonic stage (with Rca1³)

Rca1²

decreased occurrence of cell division | embryonic stage | somatic clone

Rca1²

increased cell number, with Scer\GAL4^GMR.PU

Rca1^{UAS.Tag:HA.Tag:FLAG}

increased occurrence of cell division | larval stage, with Scer\GAL4^Act5C.PI

Rca1^{UAS.Tag:HA.Tag:FLAG}

increased occurrence of cell division | larval stage, with Scer\GAL4^GMR.PU

Rca1^{UAS.Tag:HA.Tag:FLAG}

increased occurrence of cell division | third instar larval stage

mitotic cell cycle defective

Rca1²

mitotic cell cycle defective (with Rca1²)

Rca1³

mitotic cell cycle defective (with Rca1³)

Rca1²

mitotic cell cycle defective | somatic clone

neuroanatomy defective | larval stage

Rca1^GD12609

pain response defective | adult stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Rca1^GD12609

some die during pupal stage, with Scer\GAL4^arm.PS

Rca1^UAS.Tag:HA

visible, with Scer\GAL4^pnr-MD237

Rca1^GD12609

Phenotype manifest in

Allele

abdominal segment 2 & cardioblast

Rca1⁰³³⁰⁰

abdominal segment 3 & cardioblast

Rca1⁰³³⁰⁰

abdominal segment 4 & cardioblast

Rca1⁰³³⁰⁰

abdominal segment 5 & cardioblast

Rca1⁰³³⁰⁰

abdominal segment 6 & cardioblast

Rca1⁰³³⁰⁰

abdominal segment 7 & cardioblast

Rca1⁰³³⁰⁰

aCC neuron | precursor

Rca1⁰³³⁰⁰

cardioblast

Rca1^unspecified

chaeta, with Scer\GAL4^pnr-MD237

Rca1^GD12609

EL neuron

embryonic pericardial cell

Rca1⁰³³⁰⁰

eye

eye, with Scer\GAL4^GMR.PU

Rca1^{UAS.Tag:HA.Tag:FLAG}

eye disc | third instar larval stage

eye disc posterior to the morphogenetic furrow, with Scer\GAL4^GMR.PU

Rca1^{UAS.Tag:HA.Tag:FLAG}

eye disc posterior to the morphogenetic furrow | somatic clone, with Scer\GAL4^GMR.PU

Rca1^{UAS.Tag:HA.Tag:FLAG}

ganglion mother cell

Rca1⁰³³⁰⁰

ganglion mother cell | larval stage

Rca1^GD12609

ganglion mother cell GMC1-1a

ganglion mother cell GMC4-2a

larval neuroblast | larval stage

Rca1^GD12609

nucleus | somatic clone

Rca1²

pCC neuron

Rca1⁰³³⁰⁰

pCC neuron | precursor

Rca1⁰³³⁰⁰

RP2sib neuron

Rca1⁰³³⁰⁰

U neuron

Rca1⁰³³⁰⁰

wing disc | somatic clone

Rca1²

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (2)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\FBXO43

4 of 15

Yes

Hsap\FBXO5

3 of 15

Yes

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (2)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Fbxo43

4 of 15

Yes

Mmus\Fbxo5

3 of 15

Yes

Rattus norvegicus (Norway rat) (2)

Rnor\Fbxo43

4 of 13

Yes

Rnor\Fbxo5

3 of 13

Yes

Xenopus tropicalis (Western clawed frog) (2)

Xtro\fbxo43

4 of 12

Yes

Xtro\fbxo5

3 of 12

Yes

Danio rerio (Zebrafish) (2)

Drer\fbxo43

4 of 15

Yes

Drer\fbxo5

3 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (0)

No records found.

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190C7E )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA10566

Drosophila persimilis

Dper\GL26189

Drosophila persimilis

Dper\GL23201

Drosophila willistoni

Dwil\GK24784

Drosophila virilis

Dvir\GJ21279

Drosophila mojavensis

Dmoj\GI23995

Drosophila grimshawi

Dgri\GH13716

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150J6X )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ017739

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W0PWW )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Tribolium castaneum

Red flour beetle

Tcas\TC005287

Tribolium castaneum

Red flour beetle

Tcas\TC000156

Tribolium castaneum

Red flour beetle

Tcas\TC000157

Tribolium castaneum

Red flour beetle

Tcas\TC001583

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )

No non-Arthropod Metazoa orthologies identified

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (0)

No records found.

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

FBXO43; F-box protein 43

4 of 15

609110

FBXO5; F-box protein 5

3 of 15

606013

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Rca1

suppressible

CycA

(Grosskortenhaus and Sprenger, 2002)

Rca1

enhanceable

CycA

(Grosskortenhaus and Sprenger, 2002)

Rca1

suppressible

CycE

(Grosskortenhaus and Sprenger, 2002)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

CycA

enhanceable

Rca1

(Grosskortenhaus and Sprenger, 2002)

CycE

enhanceable

Rca1

(Secombe et al., 1998)

fzr

suppressible

Rca1

(Grosskortenhaus and Sprenger, 2002)

Hsp83

suppressible

Rca1

(Bandura et al., 2013)

rux

suppressible

Rca1

(Dong et al., 1997)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

60110

DroID - A comprehensive database of gene and protein interactions.

FBgn0017551

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

33959

MIST (genetic) - An integrated Molecular Interaction Database

Rca1

MIST (protein-protein) - An integrated Molecular Interaction Database

Rca1

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-23

Cytogenetic map

27C1-27C1

Sequence location

2L:6,852,315..6,853,866 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

27C1-27C1

Limits computationally determined from genome sequence between P{lacW}Ate1^k10809 and P{PZ}Rca1⁰³³⁰⁰&P{lacW}l(2)k09022^k09022

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

27B4-27C1

(Dong, 1996.11.6, BDGP Project Members, 1994-1999)

27B4-27C1

(determined by in situ hybridisation)

(Spradling et al., 1999)

Experimentally Determined Recombination Data

Location

2-23

(FlyBase, 2016)

2-22.0

(Comeron et al., 2012)

2-21

(Dong et al., 1997)

(Dong, 1996.11.6)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (14)

Bloomington

9163

w^*; P{hs-rca1}I4

9164

w^*; P{hs-rca1}C2

18068

w¹¹¹⁸; PBac{RB}Rca1^e02614

9161

Rca1² cn¹ bw¹/SM6a

80335

y¹ v¹; P{TKO.GS03296}attP40

9162

Rca1^IX cn¹ bw¹/SM6a

51680

y¹ v¹; P{TRiP.GLC01770}attP40

63598

y¹ v¹; P{TRiP.HMJ30165}attP40/CyO

11294

P{PZ}Rca1⁰³³⁰⁰ cn¹/CyO; ry⁵⁰⁶

VDRC

v35489

w¹¹¹⁸; P{GD12609}v35489

v35490

w¹¹¹⁸; P{GD12609}v35490

v318042

PBac{fTRG00124.sfGFP-TVPTBF}VK00033

More stocks available...

Genomic Clones (27)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (25)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH14043

Other clones

DPiM_GH14043

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0017551

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0017551

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

33959

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Rca1 CG10800

(Li, 1999.11)

Source for database merge of

Additional comments

Other Comments

RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly long spindles when assayed in S2 cells in the presence of Cdc27 dsRNA. This phenotype cannot be observed when the screen is performed without Cdc27 dsRNA.

(Goshima et al., 2007)

numb functions downstream of cell division genes (CycA, Rca1 and stg) and progression through the cell cycle is required for asymmetric localisation of numb and thus N mediated specification of the sib fate in the RP2/sib division.

(Wai et al., 1999)

The loss of CycA, Rca1 or stg leads to a block in the division of GMC-1, however this GMC-1 adopts a RP2 identity.

(Wai et al., 1999)

Rca1 wild type function is sufficient to drive postmitotic cells into S phase. Rca1 positively regulates CycA by modulating CycA protein levels.

(Dong et al., 1997)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 35 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33959

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0017551

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0017551

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Rca1_1

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10800

Flygut - An atlas of the Drosophila adult midgut

FBgn0017551

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

33959

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG10800

modMine - A data warehouse for the modENCODE project

FBgn0017551

Linkouts

BioGRID - A database of protein and genetic interactions.

60110

DPiM - Drosophila Protein interaction map

FBgn0017551

DroID - A comprehensive database of gene and protein interactions.

FBgn0017551

DRSC - Results frm RNAi screens

FBgn0017551

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0017551

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

CG10800-RA

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0017551

FlyMine - An integrated database for Drosophila genomics

FBgn0017551

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

33959

MIST (genetic) - An integrated Molecular Interaction Database

Rca1

MIST (protein-protein) - An integrated Molecular Interaction Database

Rca1

Synonyms and Secondary IDs (16)

Reported As

Symbol Synonym

152549_at

(Kristensen et al., 2005)

CG10800

(Hosono et al., 2015, Fukuoh et al., 2014, Roberts et al., 2012, Ni et al., 2010.12.1, Perkins et al., 2009, Goshima et al., 2007, Labourier et al., 2002)

CLD4

(Erhardt et al., 2008)

Emi1

(Kohzaki et al., 2018, Buttitta et al., 2010, Tanaka-Matakatsu et al., 2007)

FBXO5

(Roberts et al., 2012)

P3300

(Lear and Patel, 1997)

RCA1

(Erhardt et al., 2008, Acquaviva and Pines, 2006)

S(rux)2A

(Dong et al., 1997)

l(2)03300

Name Synonyms

Regulator of Cyclin A 1

(Narbonne-Reveau et al., 2008)

Regulator of cyclin A1

(Boukhatmi et al., 2014, Bandura et al., 2013, Kaplow et al., 2007)

Suppressor of rux 2A

(Dong et al., 1997)

regulator of Cyclin A

(Zielke et al., 2006)

regulator of cyclin A

(Dong et al., 1997)

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Study focus (0)

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