Emi1
a novel signaling protein that prevents cyclin degredation in G2 by interacting with Fizzy-related - inhibits Fizzy-related's activation of protein degradation machinery - mutants exhibit premature cyclin destruction
Please see the JBrowse view of Dmel\Rca1 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.52
1.577 (longest cDNA)
There is only one protein coding transcript and one polypeptide associated with this gene
412 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rca1 using the Feature Mapper tool.
Comment: maternally deposited
Rca1 transcripts are abundant and uniformly distributed in early embryos prior to cellularization. During germ band elongation in stages 8 and 9, transcripts are detected predominantly in the mesoderm and in the anterior and posterior midgut primordia. In stages 10 and 11, high levels of Rca1 transcript are observed throughout the embryo but not in the amnioserosa. By stage 13, staining is mainly restricted to the cells of the developing CNS. Weak expression is also observed in the midgut
GBrowse - Visual display of RNA-Seq signals
View Dmel\Rca1 in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Rca1 CG10800