Gene Dmel\qm

Experimentally Determined Recombination Data

Location

3-23.0

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\qm for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.45

Low-frequency RNA-seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

qm-RA

FBtr0076846

NM_079234

1934

338

qm-RB

FBtr0302045

NM_001169899

2543

338

qm-RC

FBtr0332729

NM_001274581

2507

326

Additional Transcript Data & Comments

Reported size (kB)

2.6, 2.3 (northern blot)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

qm-PA

FBpp0076557

38.8

338

7.01

NP_523958

AAF50574

qm-PB

FBpp0291255

38.8

338

7.01

NP_001163370

ACZ94641

qm-PC

FBpp0304975

37.4

326

7.63

NP_001261510

AGB94205

Additional Polypeptide Data & Comments

Reported size (kDa)

338 (aa); 39 (kD predicted)

Comments

External Data

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Polyprenyl synthetase (IPR000092)

Terpenoid synthase (IPR008949)

Polyprenyl synthetase-related (IPR017446)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment:maternally deposited

embryonic stage 11 -- 12

visceral muscle primordium

embryonic stage 13 -- 16

embryonic/larval visceral muscle

longitudinal visceral muscle fiber

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage -- adult stage

Additional Descriptive Data

qm transcripts are expressed at all stages of development.

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

(The modENCODE Consortium, 2010, Graveley et al., 2011)

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		114.2
Larval Midgut		156.4
Larval Hindgut		84.6
Larval Malpighian Tubules		87.4
Larval Fat Body		43.3
Larval Salivary Gland		43.5
Larval Trachea		48.675
Larval Carcass		47.175
Adult Head		141.3
Adult Eye		224.4
Adult Brain		280.1
Adult Thoracic-Abdominal Ganglion		157.4
Adult Crop		179.8
Adult Midgut		115
Adult Hindgut		66
Adult Malpighian Tubules		30.4
Adult Fat Body		36.6
Adult Salivary Gland		52.3
Adult Heart		58.225
Adult VirginFemale Spermatheca		36.4
Adult InseminatedFemale Spermatheca		35.1
Adult Ovary		70.9
Adult Testis		47.1
Adult Male Accessory Gland		44.7
Adult Carcass		41.8
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	141.3
NA	Eye	224.4
NA	Brain	280.1
114.2	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	157.4
NA	Crop	179.8
156.4	Midgut	115
84.6	Hindgut	66
87.4	Malpighian Tubules	30.4
43.3	Fat Body	36.6
43.5	Salivary Gland	52.3
NA	Heart	58.225
48.675	Trachea	NA
NA	VirginFemale Spermatheca	36.4
NA	InseminatedFemale Spermatheca	35.1
NA	Ovary	70.9
NA	Testis	47.1
NA	Male Accessory Gland	44.7
47.175	Carcass	41.8

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		43
central nervous system, pupae P8		38
head, virgin 1-day female		57
head, virgin 4-day female		63
head, virgin 20-day female		25
head, mated 1-day female		60
head, mated 4-day female		50
head, mated 20-day female		30
head, mated 1-day male		77
head, mated 4-day male		89
head, mated 20-day male		76
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		87
digestive system, 1-day adult		20
digestive system, 4-day adult		31
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		41
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		27
ovary, mated 4-day female		32
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		(43)
central nervous system, pupae P8		(38)
head, virgin 1-day female		(57)
head, virgin 4-day female		(63)
head, virgin 20-day female		25
head, mated 1-day female		(60)
head, mated 4-day female		(50)
head, mated 20-day female		(30)
head, mated 1-day male		(77)
head, mated 4-day male		(89)
head, mated 20-day male		(76)
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		(87)
digestive system, 1-day adult		20
digestive system, 4-day adult		(31)
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		(41)
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		(27)
ovary, mated 4-day female		(32)
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		43
central nervous system, pupae P8		38
head, virgin 1-day female		57
head, virgin 4-day female		63
head, virgin 20-day female		25
head, mated 1-day female		60
head, mated 4-day female		50
head, mated 20-day female		30
head, mated 1-day male		77
head, mated 4-day male		89
head, mated 20-day male		76
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		87
digestive system, 1-day adult		20
digestive system, 4-day adult		31
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		41
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		27
ovary, mated 4-day female		32
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		43
central nervous system, pupae P8		38
head, virgin 1-day female		57
head, virgin 4-day female		63
head, virgin 20-day female		25
head, mated 1-day female		60
head, mated 4-day female		50
head, mated 20-day female		30
head, mated 1-day male		77
head, mated 4-day male		89
head, mated 20-day male		76
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		87
digestive system, 1-day adult		20
digestive system, 4-day adult		31
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		41
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		27
ovary, mated 4-day female		32
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		43
central nervous system, pupae P8		38
head, virgin 1-day female		57
head, virgin 4-day female		63
head, virgin 20-day female		25
head, mated 1-day female		60
head, mated 4-day female		50
head, mated 20-day female		30
head, mated 1-day male		77
head, mated 4-day male		89
head, mated 20-day male		76
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		87
digestive system, 1-day adult		20
digestive system, 4-day adult		31
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		41
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		27
ovary, mated 4-day female		32
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		(43)
central nervous system, pupae P8		(38)
head, virgin 1-day female		(57)
head, virgin 4-day female		(63)
head, virgin 20-day female		25
head, mated 1-day female		(60)
head, mated 4-day female		(50)
head, mated 20-day female		30
head, mated 1-day male		(77)
head, mated 4-day male		(89)
head, mated 20-day male		(76)
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		(87)
digestive system, 1-day adult		20
digestive system, 4-day adult		31
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		(41)
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		27
ovary, mated 4-day female		32
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		43
central nervous system, pupae P8		38
head, virgin 1-day female		57
head, virgin 4-day female		63
head, virgin 20-day female		25
head, mated 1-day female		60
head, mated 4-day female		50
head, mated 20-day female		30
head, mated 1-day male		77
head, mated 4-day male		89
head, mated 20-day male		76
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		87
digestive system, 1-day adult		20
digestive system, 4-day adult		31
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		41
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		27
ovary, mated 4-day female		32
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		22
central nervous system, larvae L3		43
central nervous system, pupae P8		38
head, virgin 1-day female		57
head, virgin 4-day female		63
head, virgin 20-day female		25
head, mated 1-day female		60
head, mated 4-day female		50
head, mated 20-day female		30
head, mated 1-day male		77
head, mated 4-day male		89
head, mated 20-day male		76
salivary gland, larvae L3 wandering		2
salivary gland, white prepupae		6
digestive system, larvae L3 wandering		87
digestive system, 1-day adult		20
digestive system, 4-day adult		31
digestive system, 20-day adult		22
fat body, larvae L3 wandering		12
fat body, white prepupae		15
fat body, pupae P8		41
carcass, larvae L3 wandering		22
carcass, 1-day adult		15
carcass, 4-day adult		18
carcass, 20-day adult		15
ovary, virgin 4-day female		27
ovary, mated 4-day female		32
testis, mated 4-day male		9
accessory gland, mated 4-day male		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		27
embryo 18-20hr		36
embryo 20-22hr		26
embryo 22-24hr		35
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		28
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		(27)
embryo 18-20hr		(36)
embryo 20-22hr		26
embryo 22-24hr		(35)
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		(28)
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		27
embryo 18-20hr		36
embryo 20-22hr		26
embryo 22-24hr		35
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		28
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		27
embryo 18-20hr		36
embryo 20-22hr		26
embryo 22-24hr		35
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		28
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		27
embryo 18-20hr		36
embryo 20-22hr		26
embryo 22-24hr		35
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		28
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		27
embryo 18-20hr		(36)
embryo 20-22hr		26
embryo 22-24hr		(35)
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		28
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		27
embryo 18-20hr		36
embryo 20-22hr		26
embryo 22-24hr		35
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		28
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		22
embryo 02-04hr		20
embryo 04-06hr		6
embryo 06-08hr		8
embryo 08-10hr		14
embryo 10-12hr		21
embryo 12-14hr		24
embryo 14-16hr		17
embryo 16-18hr		27
embryo 18-20hr		36
embryo 20-22hr		26
embryo 22-24hr		35
larva L1		12
larva L2		10
larva L3 12hr old		8
larva L3 puffstage 1-2		10
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		26
white prepupae new		25
white prepupae 12hr		28
white prepupae 24hr		21
pupae 2d postWPP		13
pupae 3d postWPP		12
pupae 4d postWPP		13
adult male 01day		14
adult male 05day		12
adult male 30day		12
adult female 01day		15
adult female 05day		20
adult female 30day		20
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		51
Schneider line 2 Sg4		38
embryonic 1182-4H		26
embryonic GM2		44
embryonic Kc167		53
embryonic S1		37
embryonic S3		113
leg disc CME L1		40
wing disc CME-W2		66
wing disc ML-DmD8		76
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		29
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		30
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		115
CNS ML-DmBG1-c1		38
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		86
ovary fGS/OSS		14
ovary OSC		58
ovary OSS		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(51)
Schneider line 2 Sg4		(38)
embryonic 1182-4H		26
embryonic GM2		(44)
embryonic Kc167		(53)
embryonic S1		(37)
embryonic S3		(113)
leg disc CME L1		(40)
wing disc CME-W2		(66)
wing disc ML-DmD8		(76)
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		(29)
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		(30)
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		(29)
mixed discs ML-DmD4-c1		(115)
CNS ML-DmBG1-c1		(38)
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		(86)
ovary fGS/OSS		14
ovary OSC		(58)
ovary OSS		17
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		51
Schneider line 2 Sg4		38
embryonic 1182-4H		26
embryonic GM2		44
embryonic Kc167		53
embryonic S1		37
embryonic S3		(113)
leg disc CME L1		40
wing disc CME-W2		66
wing disc ML-DmD8		76
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		29
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		30
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		(115)
CNS ML-DmBG1-c1		38
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		86
ovary fGS/OSS		14
ovary OSC		58
ovary OSS		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		51
Schneider line 2 Sg4		38
embryonic 1182-4H		26
embryonic GM2		44
embryonic Kc167		53
embryonic S1		37
embryonic S3		113
leg disc CME L1		40
wing disc CME-W2		66
wing disc ML-DmD8		76
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		29
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		30
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		115
CNS ML-DmBG1-c1		38
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		86
ovary fGS/OSS		14
ovary OSC		58
ovary OSS		17
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		51
Schneider line 2 Sg4		38
embryonic 1182-4H		26
embryonic GM2		44
embryonic Kc167		53
embryonic S1		37
embryonic S3		113
leg disc CME L1		40
wing disc CME-W2		66
wing disc ML-DmD8		76
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		29
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		30
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		115
CNS ML-DmBG1-c1		38
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		86
ovary fGS/OSS		14
ovary OSC		58
ovary OSS		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(51)
Schneider line 2 Sg4		(38)
embryonic 1182-4H		26
embryonic GM2		(44)
embryonic Kc167		(53)
embryonic S1		(37)
embryonic S3		(113)
leg disc CME L1		(40)
wing disc CME-W2		(66)
wing disc ML-DmD8		(76)
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		29
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		30
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		(115)
CNS ML-DmBG1-c1		(38)
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		(86)
ovary fGS/OSS		14
ovary OSC		(58)
ovary OSS		17
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		51
Schneider line 2 Sg4		38
embryonic 1182-4H		26
embryonic GM2		44
embryonic Kc167		53
embryonic S1		37
embryonic S3		113
leg disc CME L1		40
wing disc CME-W2		66
wing disc ML-DmD8		76
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		29
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		30
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		115
CNS ML-DmBG1-c1		38
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		86
ovary fGS/OSS		14
ovary OSC		58
ovary OSS		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		51
Schneider line 2 Sg4		38
embryonic 1182-4H		26
embryonic GM2		44
embryonic Kc167		53
embryonic S1		37
embryonic S3		113
leg disc CME L1		40
wing disc CME-W2		66
wing disc ML-DmD8		76
wing disc ML-DmD9		23
wing disc ML-DmD16-c3		29
wing disc ML-DmD21		16
wing disc ML-DmD32		23
haltere disc ML-DmD17-c3		30
eye-antennal disc ML-DmD11		23
antennal disc ML-DmD20-c5		29
mixed discs ML-DmD4-c1		115
CNS ML-DmBG1-c1		38
CNS ML-DmBG2-c2		23
tumorous blood cells mbn2		86
ovary fGS/OSS		14
ovary OSC		58
ovary OSS		17
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		28
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		39
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		29
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		31
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		28
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		(28)
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		(37)
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		(47)
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		(39)
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		(29)
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(33)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(31)
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		(28)
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		28
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		39
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		29
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		31
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		28
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		28
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		39
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		29
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		31
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		28
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		28
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		39
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		29
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		31
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		28
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		28
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		(37)
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		(47)
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		(39)
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		29
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(33)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		31
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		28
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		28
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		39
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		29
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		31
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		28
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		14
heat shock, 4-day adult		24
Cadmium 50 mM 6 hrs, larvae L3		18
Cadmium 50 mM 12 hrs, larvae L3		28
Cadmium 50 mM 48 hrs, 4-day adult		26
Cadmium 100 mM 48 hrs, 4-day adult		37
Copper 0.5 mM 12 hrs, larvae L3		14
Copper 15 mM 48 hrs, 4-day adult		47
Zinc 5 mM 12 hrs, larvae L3		11
Zinc 4.5 mM 48 hrs, 4-day adult		39
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		29
Ethanol 10% 3 hrs, larvae L3		17
Caffeine 1.5 mg/ml 4 hrs, larvae L3		33
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		31
Caffeine 25 mg/ml 48 hrs, 4-day adult		18
Paraquat 5 mM 48 hrs, 4-day adult		28
Paraquat 10 mM 48 hrs, 4-day adult		26
Rotenone 2 μg 12 hrs, larvae L3		23
Rotenone 8 μg 12 hrs, larvae L3		16
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

External Data & Images

Show all FlyExpress processed images for qm

BDGP expression data

•

RE65121

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0019662

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG8593-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Stages(s) 1-3

Stages(s) 11-12

Stages(s) 13-16

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal

qm^GD4696

lethal | larval stage | recessive

qm^L14.4

lethal | pupal stage | recessive

qm^15.1

partially lethal - majority die | pupal stage, with Scer\GAL4^pnr-MD237

qm^GD4696

viable

Sterility

Allele

female fertile

qm⁵⁷

female sterile | germline clone

qm^L14.4

fertile

male sterile | recessive

qm⁵⁷

Other Phenotypes

Allele

neuroanatomy defective | larval stage

qm^GD4696

visible, with Scer\GAL4^pnr-MD237

qm^GD4696

visible | recessive

wild-type

Phenotype manifest in

Allele

adult abdomen

qm^15.1

adult cuticle & abdomen

qm^15.1

adult thorax & macrochaeta

cardioblast

qm^L14.4

cephalopharyngeal skeleton

qm^L14.4

embryonic/larval neuroblast | larval stage

qm^GD4696

embryonic pericardial cell

qm^L14.4

ganglion mother cell | larval stage

qm^GD4696

head bristle

larva

qm^L14.4

macrochaeta

macrochaeta & adult abdomen

qm^15.1

pole cell

qm^L14.4

pole cell & embryonic nervous system, with Scer\GAL4^elav-C155

qm^Scer\UAS.cSa

sex comb

qm⁵⁷

sternopleural bristle

qm¹

trichogen cell, with Scer\GAL4^pnr-MD237

qm^GD4696

Classical Alleles ( 17 )

For All Classical Alleles Show

Allele of qm	Mutagen	Stocks	Known lesion
qm^f01604	piggyBac transposase	2	--
qm^L14.4	ethyl methanesulfonate	2	Yes
qm²	spontaneous	1	--
qm^EY08197	P-element activity	1	--
qm^NP6568		1	--
qm^15.1	ethyl methanesulfonate	0	Yes
qm¹	PM hybrid dysgenesis	0	Yes
qm⁵⁷		0	--
qm⁵⁸	Delta2-3	0	--
qm⁶³	Delta2-3	0	--
qm⁸⁶	Delta2-3	0	--
qm⁸⁷	Delta2-3	0	--
qm⁸⁹	P-element activity	0	Yes
qm^CB-6966-3		0	--
qm^rev31	Delta2-3	0	Yes
qm^rev39	Delta2-3	0	Yes
qm^rev69	Delta2-3	0	Yes

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of qm	Mutagen	Stocks	Known lesion
qm^GD4696	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
qm^KK108879	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
qm^+t11.5	in vitro construct - genomic fragment	0	Yes
qm^Scer\UAS.cSa	in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3L)BSC33

(Andrade and Cook, 2003.4.2)

Df(3L)Hn^DEB

Not disrupted in

Df(3L)pbl-X1

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD4696}

P{KK108879}

P{UAS-qm.S}

characterization construct

P{CSX11.5}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}qm^EY08197

insertion of enhancer trap binary system

P{GawB}qm^NP6568

miscellaneous insertions

P{}qm¹

P{}qm⁵⁸

P{}qm⁸⁶

P{}qm⁸⁷

P{}qm⁸⁹

P{RS3}qm^CB-6966-3

PBac{WH}qm^f01604

Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )

Terms Based on Experimental Evidence ( 3 terms )

Molecular Function ( 0 terms)

Biological Process

CV term

embryonic heart tube development

References

inferred from mutant phenotype

(Yi et al., 2006)

germ cell migration

inferred from mutant phenotype

(Santos and Lehmann, 2004)

neurogenesis

inferred from mutant phenotype

(Neumüller et al., 2011)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 4 terms )

Molecular Function

CV term

dimethylallyltranstransferase activity

References

inferred from sequence or structural similarity with UniProtKB:P24322

(FlyBase, 1992-)

farnesyltranstransferase activity

inferred from sequence or structural similarity with UniProtKB:P24322

(FlyBase, 1992-)

non-traceable author statement

(Lai, 1998.2.19)

geranyltranstransferase activity

inferred from sequence or structural similarity with UniProtKB:P24322

(FlyBase, 1992-)

Biological Process

CV term

isoprenoid biosynthetic process

References

inferred from electronic annotation with InterPro:IPR000092

(FlyBase Curators et al., 2004-)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

qm allele

Gene

References

qm^L14.4

Hmgcr

(Santos and Lehmann, 2004)

External Data

y¹ w^67c23; P{EPgy2}qm^EY08197

BioGRID - A database of protein and genetic interactions

•

64256

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0019662

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

38816

Orthologs

OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6TB4XC

Dipteran inclusive ortholog search

EOG6SN1XF

Insect inclusive ortholog search

EOG6ZS7ZZ

Arthropod inclusive ortholog search

EOG66WWR5

Metazoa inclusive ortholog search

EOG6JTC0B

Orthologs in Drosophila Species (EOG6TB4XC)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA21189

Drosophila persimilis

Dper\GL21354

Drosophila willistoni

Dwil\GK17525

Drosophila virilis

Dvir\GJ13129

Drosophila mojavensis

Dmoj\GI12986

Drosophila grimshawi

Dgri\GH15381

Orthologs in non-Drosophila Dipterans (EOG6SN1XF)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL004900

Anopheles gambiae

Malaria mosquito

Agam\AGAP006894

Orthologs in non-Dipteran Insects (EOG6ZS7ZZ)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB43964

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG013958

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH16303

Atta cephalotes

Leafcutter ant

Acep\ACEP16638

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO17447

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL23200

Linepithema humile

Argentine ant

Lhum\LH18936

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB11674

Solenopsis invicta

Red fire ant

Sinv\SINV22576

Solenopsis invicta

Red fire ant

Sinv\SINV17154

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI002857

Bombyx mori

Silkmoth

Bmor\BGIBMGA002401

Pediculus humanus

Human body louse

Phum\PHUM424740

Tribolium castaneum

Red flour beetle

Tcas\TC004978

Orthologs in non-Insect Arthropods (EOG66WWR5)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\Wdhd1

Ixodes scapularis

Deer tick

Isca\ISCW023301

Orthologs in non-Arthropod Metazoa (EOG6JTC0B)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_013853gn

Danio rerio

Zebrafish

Drer\ggps1

Xenopus tropicalis

Western clawed frog

Xtro\ggps1

Gallus gallus

Domestic chicken

Ggal\GGPS1

Mus musculus

House mouse

Mmus\Ggps1

Rattus norvegicus

Norway rat

Rnor\Ggps1

Homo sapiens

Human

Hsap\GGPS1

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\GGPS1

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA21189

Drosophila persimilis

Dper\GL21354

Drosophila willistoni

Dwil\GK17525

Drosophila virilis

Dvir\GJ13129

Drosophila mojavensis

Dmoj\GI12986

Drosophila grimshawi

Dgri\GH15381

Stocks & Reagents

Stocks Listed in FlyBase ( 10 )

Bloomington

5827

w¹¹¹⁸; qm²

5828

w¹¹¹⁸; qm^L14.4/TM6B, Tb¹

16878

18452

w¹¹¹⁸; PBac{WH}qm^f01604 CTCF^f01604

Harvard

PBac{WH}qm^f01604

Kyoto

108450

w¹¹¹⁸; qm^L14.4/TM6B, Tb¹

105261

y^* w^*; P{GawB}qm^NP6568 / TM6, P{UAS-lacZ.UW23-1}UW23-1

VDRC

v101499

P{KK108879}VIE-260B

v47001

w¹¹¹⁸ P{GD4696}v47001

v47000

w¹¹¹⁸; P{GD4696}v47000

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 41 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

RE65121

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

DRSC - Results from RNAi screens.

•

FBgn0019662

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

38816

Antibody Information

Other Information

Discoverer

Etymology

The gene is named "quemao" for the mutant phenotype: "Que mao" in Chinese means "loss of hairs" and qm[1] mutants lack most of the macrochaetae on the body.