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Gene Dmel\Rh6

General Information
Symbol	Dmel\Rh6	Species	D. melanogaster
Name	Rhodopsin 6	Annotation symbol	CG5192
Feature type	protein_coding_gene	FlyBase ID	FBgn0019940
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	88F6-88F6	Sequence location	3R:11,308,880..11,310,421 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Rhodopsin 6 is referred to in FlyBase by the symbol Dmel\Rh6 (CG5192, FBgn0019940). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: G-protein coupled photoreceptor activity. There is experimental evidence that it is involved in the biological process: phototransduction; sensory perception of sound; negative regulation of transcription from RNA polymerase II promoter. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: G protein-coupled receptor, rhodopsin-like; GPCR, rhodopsin-like, 7TM; Opsin; Opsin RH1/RH2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye. Comments on Affy2 ProbeSet: ProbeSet 1640642_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Rh6. Gene sequence location is 3R:11308880..11310421.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02	Controlled Vocabulary Terms Johnston organ Unknown in situ
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 88F6-88F6   Limits computationally determined from genome sequence between P{lacW}MRG15j6A3 and P{PZ}l(3)0653606536
Experimentally Determined Cytological Location
Cytogenetic map Notes References 88F-88F   (determined by in situ hybridisation)   (Huber et al., 1997)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Rh6 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.47 Known mutation in sequenced strain, Rh6[1]. Replace with wild type sequence from GenBank accession Z86118
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Rh6-RB FBtr0083146  NM_079644   1474   369
Additional Transcript Data & Comments
Reported size (kB)	1.4 (northern blot) (Huber et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Rh6-PB   FBpp0082600   41.7   369   8.58     NP_524368   AAN13666
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • G protein-coupled receptor, rhodopsin-like (IPR000276) Opsin RH1/RH2 (IPR001735) Opsin (IPR001760) GPCR, rhodopsin-like, 7TM (IPR017452) Visual pigments (opsins) retinal binding site (IPR027430)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014297 AAN13666   AI405651   AY089666 AAL90404   BI564387   BI609130   BI616104   BX021985   BX045822   CK134988   CO186557   CO267686   CO268540   CO272782   CO291618   CO302776   CO304638   EC052169   EC052181   EC054674   EC054694   EC055741   EC059580   EC061715   EC074975   EC087535   EC194805   EC211829   EC236929   EC249771   EL881321   Z86118
UniProtKB/Swiss-Prot	O01668
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References regulatory region FBsf0000435584 3R:11,308,342..11,308,925 evidence=Reporter construct (in vivo) (Papatsenko et al., 2001, Halfon, 2012.6.19) regulatory region FBsf0000435865 3R:11,308,325..11,309,001 evidence=Reporter construct (in vivo) (Tahayato et al., 2003, Halfon, 2012.6.19)
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
expression microarray Stage Tissue/Position (including subcellular localization) Reference adult stage   eye   (Xu et al., 2004) in situ Stage Tissue/Position (including subcellular localization) Reference adult stage   Johnston organ   (Senthilan et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference adult stage   photoreceptor cell R8 | subset   (Huber et al., 1997) adult head   (Huber et al., 1997)
Additional Descriptive Data
	Rh6 is inferred to be expressed in R8 cells, as hybridization signals were detected in the basal part of the retinula cell layer, close to the R8 cell nuclei. (Huber et al., 1997) Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads. (Xu et al., 2004)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference adult stage   photoreceptor cell R8 | subset   (Baumann and Lutz, 2006) eyelet photoreceptor   (Yasuyama and Meinertzhagen, 1999) rhabdomere of eye photoreceptor cell   • microvillus (Yasuyama and Meinertzhagen, 1999) rhabdomere R8 | subset   (Yasuyama and Meinertzhagen, 1999)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
rhabdomere inferred from direct assay (Salcedo et al., 1999)
Expression Deduced from Reporters
Reporter: P{Rh6-lacZ.-470} Stage Tissue/Position (including subcellular localization) Reference third instar larval stage   Bolwig nerve   (Malpel et al., 2002) adult stage   photoreceptor cell R8 | subset   (Papatsenko et al., 2001)
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head    1230.6 Adult Eye    973.075 Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head  (1230.6) Adult Eye  (973.075) Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head  (1230.6) Adult Eye    973.075 Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head    1230.6 Adult Eye    973.075 Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head    1230.6 Adult Eye    973.075 Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head  (1230.6) Adult Eye  (973.075) Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head  1230.6 Adult Eye    973.075 Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    17.8 Larval Midgut    21.2 Larval Hindgut    9.4 Larval Malpighian Tubules    11 Larval Fat Body    24.1 Larval Salivary Gland    17.2 Larval Trachea    16.15 Larval Carcass    25.925 Adult Head    1230.6 Adult Eye    973.075 Adult Brain    19.8 Adult Thoracic-Abdominal Ganglion    14.2 Adult Crop    13.7 Adult Midgut    29.6 Adult Hindgut    11.1 Adult Malpighian Tubules    5.7 Adult Fat Body    22.1 Adult Salivary Gland    22 Adult Heart    9.475 Adult VirginFemale Spermatheca    18.9 Adult InseminatedFemale Spermatheca    20.6 Adult Ovary    1.4 Adult Testis    9.9 Adult Male Accessory Gland    19.4 Adult Carcass    24.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1230.6   NA  Eye    973.075   NA  Brain    no informative data   no informative data  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    no informative data   no informative data  Midgut    no informative data   9.4  Hindgut    no informative data   no informative data  Malpighian Tubules    5.7   no informative data  Fat Body    no informative data   no informative data  Salivary Gland    no informative data   NA  Heart    9.475   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    1.4   NA  Testis    9.9   NA  Male Accessory Gland    no informative data   no informative data  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    137 head, virgin 4-day female    213 head, virgin 20-day female    192 head, mated 1-day female    179 head, mated 4-day female    221 head, mated 20-day female    139 head, mated 1-day male    288 head, mated 4-day male    443 head, mated 20-day male    415 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female  (137) head, virgin 4-day female  (213) head, virgin 20-day female  (192) head, mated 1-day female  (179) head, mated 4-day female  (221) head, mated 20-day female  (139) head, mated 1-day male  (288) head, mated 4-day male  (443) head, mated 20-day male  (415) salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female  (137) head, virgin 4-day female  (213) head, virgin 20-day female  (192) head, mated 1-day female  (179) head, mated 4-day female  (221) head, mated 20-day female  (139) head, mated 1-day male  (288) head, mated 4-day male  (443) head, mated 20-day male  (415) salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    137 head, virgin 4-day female    213 head, virgin 20-day female    192 head, mated 1-day female    179 head, mated 4-day female    221 head, mated 20-day female    139 head, mated 1-day male    288 head, mated 4-day male    443 head, mated 20-day male    415 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    137 head, virgin 4-day female    213 head, virgin 20-day female    192 head, mated 1-day female    179 head, mated 4-day female    221 head, mated 20-day female    139 head, mated 1-day male    288 head, mated 4-day male    443 head, mated 20-day male    415 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female  (137) head, virgin 4-day female  (213) head, virgin 20-day female  (192) head, mated 1-day female  (179) head, mated 4-day female  (221) head, mated 20-day female  (139) head, mated 1-day male  (288) head, mated 4-day male  (443) head, mated 20-day male  (415) salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female  137 head, virgin 4-day female  (213) head, virgin 20-day female  (192) head, mated 1-day female  (179) head, mated 4-day female  (221) head, mated 20-day female  139 head, mated 1-day male  (288) head, mated 4-day male  (443) head, mated 20-day male  (415) salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    1 central nervous system, pupae P8    0 head, virgin 1-day female    137 head, virgin 4-day female    213 head, virgin 20-day female    192 head, mated 1-day female    179 head, mated 4-day female    221 head, mated 20-day female    139 head, mated 1-day male    288 head, mated 4-day male    443 head, mated 20-day male    415 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    7 carcass, 1-day adult    0 carcass, 4-day adult    1 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    1 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    2 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    0 white prepupae new    0 white prepupae 12hr    0 white prepupae 24hr    0 pupae 2d postWPP    0 pupae 3d postWPP    0 pupae 4d postWPP    4 adult male 01day    4 adult male 05day    7 adult male 30day    11 adult female 01day    3 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    0 embryonic S1    1 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    0 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    32 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult  (45) Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult  (32) Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult  (27) Paraquat 10 mM 48 hrs, 4-day adult  (31) Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    32 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    32 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    32 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult  (45) Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult  32 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult  27 Paraquat 10 mM 48 hrs, 4-day adult  31 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    32 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    10 cold shock, 4-day adult    7 heat shock, 4-day adult    8 Cadmium 50 mM 6 hrs, larvae L3    4 Cadmium 50 mM 12 hrs, larvae L3    2 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    32 Ethanol 2.5% 3 hrs, larvae L3    19 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    3 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    21 Caffeine 25 mg/ml 48 hrs, 4-day adult    10 Paraquat 5 mM 48 hrs, 4-day adult    27 Paraquat 10 mM 48 hrs, 4-day adult    31 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • RH34017 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0019940 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5192-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 Rh6GD744 Other Phenotypes Allele auditory perception defective | adult stage Rh61 neurophysiology defective | adult stage Rh61 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Rh6 Class Mutagen Stocks Known lesion Rh61 amorphic allele - genetic evidence 4 -- Rh6fs hypomorphic allele - molecular evidence 0 Yes
Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Rh6 Class Mutagen Stocks Known lesion Rh6GD744 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Rh6KK110924 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Rh6+t2.6 in vitro construct - genomic fragment 0 Yes Rh6ninaE.PS in vitro construct - regulatory fusion 0 Yes Rh6S313A.ninaE in vitro construct - regulatory fusion in vitro construct - amino acid replacement 0 Yes Rh6Scer.UAS.cVa in vitro construct - regulatory fusion 0 Yes Rh6Scer\UAS.T:Avic\GFP-EGFP in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6174 (Ryder, 2004.4.26, Vasiliauskas et al., 2011)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data reporter construct P{Rh3-lacZ.Rh6.RCSI} No P{Rh5-lacZ.Rh6.RCSI} No P{Rh6-lacZ.-470} No P{Rh6-lacZ.-555+121} No P{Rh6-lacZ.KI.CGC} No P{Rh6-lacZ.KI.KII} No P{Rh6-lacZ.KI.TG} No P{Rh6-lacZ.KII} No P{Rh6-lacZ.PT} No P{Rh6-lacZ.tau} No UAS construct P{GD744} NA P{KK110924} NA P{UAS-Rh6-EGFP} NA GAL4 construct P{Rh6-GAL4.KI.CGC} No P{Rh6-GAL4.KI.KII} No P{Rh6-GAL4.KI.TG} No P{Rh6-GAL4.KII} No characterization construct P{ninaE-Rh6.S313A} NA P{Rh1+6} NA P{Rh6+t2.6} NA P{Rh6-GAL4.D} NA P{Rh6-mCD8-GFP} NA P{UAS-Rh6.V} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function
CV term Evidence References
G-protein coupled photoreceptor activity inferred from genetic interaction with ninaE (Salcedo et al., 1999)
Biological Process
CV term Evidence References
negative regulation of transcription from RNA polymerase II promoter inferred from mutant phenotype (Vasiliauskas et al., 2011) phototransduction inferred from genetic interaction with ninaE (Salcedo et al., 1999) sensory perception of sound inferred from mutant phenotype (Senthilan et al., 2012)
Cellular Component
CV term Evidence References
rhabdomere inferred from direct assay (Salcedo et al., 1999)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
G-protein coupled photoreceptor activity inferred from sequence or structural similarity (Brody and Cravchik, 2000) inferred from sequence or structural similarity with Rh2 AND inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 AND inferred from sequence or structural similarity with ninaE (Huber et al., 1997) non-traceable author statement (Pichaud et al., 1999, Swiss-Prot Project Members, 1998.2.1)
Biological Process
CV term Evidence References
G-protein coupled receptor signaling pathway inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Brody and Cravchik, 2000) phototransduction inferred from sequence or structural similarity with Rh2 AND inferred from sequence or structural similarity with Rh3 AND inferred from sequence or structural similarity with Rh4 AND inferred from sequence or structural similarity with ninaE (Huber et al., 1997) non-traceable author statement (Montell, 1999) visual perception inferred from electronic annotation with InterPro:IPR001760 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR000276, InterPro:IPR001735, InterPro:IPR001760 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Brody and Cravchik, 2000) non-traceable author statement (Swiss-Prot Project Members, 1998.2.1)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Rh6 allele Gene References Rh6ninaE.PS ninaE (Salcedo et al., 1999)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66950 DroID - A comprehensive database of gene and protein interactions. • FBgn0019940 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41889
Orthologs
OrthoDB Orthologs (73) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG683DQH Dipteran inclusive ortholog search EOG61ZFKD Insect inclusive ortholog search EOG6DZ0QR Arthropod inclusive ortholog search EOG61VHJD Metazoa inclusive ortholog search EOG6C5RC2
Orthologs in Drosophila Species (EOG683DQH)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Rh6     Drosophila simulans   Dsim\GD19028 Y   Drosophila sechellia   Dsec\GM24240     Drosophila sechellia   Dsec\GM24238 Y   Drosophila erecta   Dere\GG16931 Y   Drosophila yakuba   Dyak\GE24316 Y   Drosophila ananassae   Dana\GF18302 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA26731 Y   Drosophila persimilis   Dper\GL23758 Y   Drosophila willistoni   Dwil\GK11464 Y   Drosophila virilis   Dvir\GJ22883 Y   Drosophila mojavensis   Dmoj\GI23224 Y   Drosophila grimshawi   Dgri\GH19080 Y
Orthologs in non-Drosophila Dipterans (EOG61ZFKD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005625 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL007389 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006484 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005621 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006498 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL006259 Y Anopheles gambiae Malaria mosquito  Agam\GPROP3 Y Anopheles gambiae Malaria mosquito  Agam\GPROP5 Y Anopheles gambiae Malaria mosquito  Agam\GPROP6 Y Anopheles gambiae Malaria mosquito  Agam\GPROP7 Y Anopheles gambiae Malaria mosquito  Agam\GPROP1 Y Anopheles gambiae Malaria mosquito  Agam\GPROP3 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011574 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ012052 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ020021 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011573 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011576 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ011571 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ004067 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ013056 Y
Orthologs in non-Dipteran Insects (EOG6DZ0QR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Lop2 Y Apis mellifera Western honey bee  Amel\Lop1 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003379 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG003380 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18074 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18073 Y Atta cephalotes Leafcutter ant  Acep\ACEP19445 Y Atta cephalotes Leafcutter ant  Acep\ACEP19443 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO13353 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO13350 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18599 Y Linepithema humile Argentine ant  Lhum\LH12077 Y Linepithema humile Argentine ant  Lhum\LH12072 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB12069 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB27366 Y Solenopsis invicta Red fire ant  Sinv\SINV11463 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009332 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007786 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007787 Y Pediculus humanus Human body louse  Phum\PHUM310950 Y Tribolium castaneum Red flour beetle  Tcas\TC013765 Y
Orthologs in non-Insect Arthropods (EOG61VHJD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\LOPB7 Y Daphnia pulex Water flea  Dpux\matK Y Daphnia pulex Water flea  Dpux\LOPA6 Y Daphnia pulex Water flea  Dpux\LOPB2 Y Daphnia pulex Water flea  Dpux\LOPA1 Y Daphnia pulex Water flea  Dpux\PRSS57 Y Daphnia pulex Water flea  Dpux\matK Y Daphnia pulex Water flea  Dpux\matK Y Daphnia pulex Water flea  Dpux\GK Y Daphnia pulex Water flea  Dpux\LOPB3 Y Daphnia pulex Water flea  Dpux\Dqx1 Y Daphnia pulex Water flea  Dpux\ARMCX5 Y Daphnia pulex Water flea  Dpux\matK Y Daphnia pulex Water flea  Dpux\LOPA7 Y Daphnia pulex Water flea  Dpux\LOPA4 Y Daphnia pulex Water flea  Dpux\LOPB4 Y Daphnia pulex Water flea  Dpux\matK Y Daphnia pulex Water flea  Dpux\LOPB6 Y
Orthologs in non-Arthropod Metazoa (EOG6C5RC2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_002311gn Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD19028 Drosophila sechellia Dsec\GM24238 Drosophila erecta Dere\GG16931 Drosophila yakuba Dyak\GE24316 Drosophila ananassae Dana\GF18302 Drosophila pseudoobscura pseudoobscura Dpse\GA26731 Drosophila persimilis Dper\GL23758 Drosophila willistoni Dwil\GK11464 Drosophila virilis Dvir\GJ22883 Drosophila mojavensis Dmoj\GI23224 Drosophila grimshawi Dgri\GH19080
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	2057 y1; Gr22b1 Gr22d1 cn1 CG33964R4.2 bw1 sp1; LysC1 MstProx1 GstD51 Rh61
Kyoto	109600 Rh61 109601 Rh61 ninaE17
UC San Diego	14021-0231.36 y1; Gr22b1 Gr22d1 cn1 CG33964R4.2 bw1 sp1; LysC1 MstProx1 GstD51 Rh61
VDRC	v102152 P{KK110924}VIE-260B v1836 w1118; P{GD744}v1836
Genomic Clones ( 1 )
	BACR17K19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 25 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH34017
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH25759 RH45879
Other clones	38337 61458 70298 99130 103928 160247 CK01.21D.A12 CK01.120B.H4 EC052169 EC052181 EC054674 EC054694 EC055741 EK020927 EK091862 EK108402 EK151517 EK184862 EK197829 EK245362 IP11114 RH13874
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0019940 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41889
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Rh6 CG5192 (Zheng, 1999.11)
Source for database merge of
Additional comments
Other Comments
	Isolated from a Drosophila head cDNA library using a Calliphora cDNA as a probe. (Huber et al., 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079644 RefSeq (Proteins) • NP_524368 DDBJ / EMBL / GenBank • AAL90404 AAN13666 AY089666 BI564387 BI609130 CAB06821 Z86118 Entrez Gene - A searchable database of RefSeq genes. • 41889 UniProtKB/Swiss-Prot • O01668
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • G protein-coupled receptor, rhodopsin-like (IPR000276) Opsin RH1/RH2 (IPR001735) Opsin (IPR001760) GPCR, rhodopsin-like, 7TM (IPR017452) Visual pigments (opsins) retinal binding site (IPR027430) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RH34017
Linkouts
	BioGRID - A database of protein and genetic interactions • 66950 DroID - A comprehensive database of gene and protein interactions. • FBgn0019940 DRSC - Results from RNAi screens. • FBgn0019940 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0019940 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5192-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0019940 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41889 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41889 modMine - Data generated by the modENCODE project. • FBgn0019940
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	CG5192 (Keleman et al., 2009.8.5) DMELRH6 (Papatsenko et al., 2001) Dm Rh6 (Townson et al., 1998) R8 (Edwards and Meinertzhagen, 2009) Rh (Fanning and Anderson, 1999) Rh6 (Yang et al., 2005, Sarfare et al., 2005, Mikeladze-Dvali et al., 2005, Earl and Britt, 2006, Jukam and Desplan, 2007, Bazigou et al., 2007, Pistillo et al., 2007, Morey et al., 2007, Friedrich, 2006, Cook et al., 2003, Hassan et al., 2005, Sprecher et al., 2007, Nelson et al., 2005, Hummel and Klaembt, 2006, Hsiao et al., 2008, Sprecher and Desplan, 2008, Dolezelova et al., 2007, Sprecher et al., 2011, Bao and Friedrich, 2009, Yuan et al., 2011, Johnston et al., 2011, Xie et al., 2007, Miller et al., 2008, Salcedo et al., 2009, Birkholz et al., 2009, Wernet et al., 2006, Lai et al., 2007, Hanai and Ishida, 2009, Baumann and Lutz, 2006, Morey et al., 2008, Birkholz et al., 2009, Hanai et al., 2008, Mishra et al., 2010, Burgler and Macdonald, 2005, McDonald et al., 2010, Xiang et al., 2010, Jumbo-Lucioni et al., 2010, Yamaguchi et al., 2008, Terrell et al., 2012, Senthilan et al., 2012, Nfonsam et al., 2012) rh6 (Tahayato et al., 2003, Mikeladze-Dvali et al., 2005, Cook et al., 2003, Pistillo et al., 2004, Cook, 2003, Wernet et al., 2002, Mollereau et al., 2002, Desplan et al., 2002, Pichaud et al., 2002, Sonneville et al., 2000, Beaufils et al., 1998, Beaufils et al., 1997, Jukam et al., 2006, Vasiliauskas et al., 2007, Mikeladze-Dvali et al., 2005, Edgar, 2006, Vasiliauskas et al., 2007, Vasiliauskas et al., 2008, Jukam and Claude, 2008, Keene et al., 2011, Vasiliauskas et al., 2011, Yamaguchi et al., 2008, Mazzoni et al., 2008, Sprecher and Desplan, 2008, Yamaguchi et al., 2010, Shen et al., 2011, Yuan et al., 2011, Posnien et al., 2012) RH6 (Malpel et al., 2001)
Name Synonym	R8 rhodopsin (Edwards and Meinertzhagen, 2009) rhodopsin (Wernet and Desplan, 2004, Harteneck, 2003, Suel et al., 2002, Dan et al., 2001, Suel and Ranganathan, 1999, Xu et al., 1998) Rhodopsin (Voets and Nilius, 2003, Montell, 2000, Satoh et al., 2002, Hardie and Raghu, 2001) Rhodopsin 6 (Earl and Britt, 2006, Bateman and McNeill, 2005, Sprecher et al., 2011, Lai et al., 2007) rhodopsin 6 (McDonald et al., 2006, Vasiliauskas et al., 2011, Yuan et al., 2011) rhodopsin-6 (Baumann and Lutz, 2006) Rhodopsin6 (Keene et al., 2011)
Secondary FlyBase IDs
References ( 145 )
Generate a list of	All references relating to this gene ( 145 )
List References by type	Research paper  ( 71 ) Supplementary material  ( 3 ) Review  ( 18 ) Personal communication to FlyBase  ( 8 ) Abstract  ( 39 ) FlyBase analysis  ( 1 ) Curated genome annotation  ( 3 ) Protein sequence record  ( 1 )
Recent research papers ( 17 )
	Hsiao et al., 2012, J. Vis. Exp.: Dissection and immunohistochemistry of larval, pupal and adult Drosophila retinas. [FBrf0220029] Kim et al., 2012, Nat. Neurosci. 15(6): 876--883 Contribution of visual and circadian neural circuits to memory for prolonged mating induced by rivals. [FBrf0219349] Nfonsam et al., 2012, PLoS ONE 7(8): e44583 Analysis of the Transcriptomes Downstream of Eyeless and the Hedgehog, Decapentaplegic and Notch Signaling Pathways in Drosophila melanogaster. [FBrf0219414] Posnien et al., 2012, PLoS ONE 7(5): e37346 Evolution of Eye Morphology and Rhodopsin Expression in the Drosophila melanogaster Species Subgroup. [FBrf0218497] Senthilan et al., 2012, Cell 150(5): 1042--1054 Drosophila auditory organ genes and genetic hearing defects. [FBrf0219321] Szular et al., 2012, J. Biol. Rhythms 27(1): 25--36 Rhodopsin 5- and Rhodopsin 6-Mediated Clock Synchronization in Drosophila melanogaster Is Independent of Retinal Phospholipase C-β Signaling. [FBrf0217408] Terrell et al., 2012, Dev. Dyn. 241(1): 215--228 OTX2 and CRX rescue overlapping and photoreceptor-specific functions in the Drosophila eye. [FBrf0216943] Wardill et al., 2012, Science 336(6083): 925--931 Multiple spectral inputs improve motion discrimination in the Drosophila visual system. [FBrf0218379] Wernet et al., 2012, Curr. Biol. 22(1): 12--20 Genetic dissection reveals two separate retinal substrates for polarization vision in Drosophila. [FBrf0217218] Johnston et al., 2011, Cell 145(6): 956--968 Interlocked feedforward loops control cell-type-specific rhodopsin expression in the Drosophila eye. [FBrf0213864] Keene et al., 2011, J. Neurosci. 31(17): 6527--6534 Distinct visual pathways mediate Drosophila larval light avoidance and circadian clock entrainment. [FBrf0213587] Klarsfeld et al., 2011, J. Neurosci. 31(48): 17406--17415 Identifying specific light inputs for each subgroup of brain clock neurons in Drosophila larvae. [FBrf0216850] Shen et al., 2011, Science 331(6022): 1333--1336 Function of rhodopsin in temperature discrimination in Drosophila. [FBrf0213227] Sprecher et al., 2011, Dev. Biol. 358(1): 33--43 The Drosophila larval visual system: High-resolution analysis of a simple visual neuropil. [FBrf0215208] Tong et al., 2011, Neuron 71(3): 447--459 Rich Regulates Target Specificity of Photoreceptor Cells and N-Cadherin Trafficking in the Drosophila Visual System via Rab6. [FBrf0214681] Vasiliauskas et al., 2011, Nature 479(7371): 108--112 Feedback from rhodopsin controls rhodopsin exclusion in Drosophila photoreceptors. [FBrf0216554] Yuan et al., 2011, Science 333(6048): 1458--1462 Light-induced structural and functional plasticity in Drosophila larval visual system. [FBrf0215276] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...