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Gene Dmel\stet

General Information
Symbol	Dmel\stet	Species	D. melanogaster
Name	stem cell tumor	Annotation symbol	CG33166
Feature type	protein_coding_gene	FlyBase ID	FBgn0020248
Gene Model Status	Current	Stock availability	11 publicly available
Also Known As	Rho-2, Brho, Rho2
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	62A2-62A2	Sequence location	3L:1,475,429..1,489,547 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene stem cell tumor is referred to in FlyBase by the symbol Dmel\stet (CG33166, FBgn0020248). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: serine-type peptidase activity. It is reported to be involved in the biological process: epidermal growth factor receptor signaling pathway. 35 alleles are reported. The phenotypes of these alleles are annotated with: organ system; multicellular structure; anatomical structure; portion of tissue; ovariole; multi-tissue structure; cell part; acellular anatomical structure; adult segment; cell periphery; organ system subdivision; gonadal sheath. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: EF-HAND 2; EF-hand-like domain; Peptidase S54, rhomboid; Peptidase S54, rhomboid domain; Peptidase S54, rhomboid, metazoan. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1641652_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of stet. Gene sequence location is 3L:1475429..1489547.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Parrott et al., 2011, PLoS ONE 6(9): e25087 Sequence features BKN22590 HFA08283 HFA08246
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 62A2-62A2   Limits computationally determined from genome sequence between P{EP}rhoEP3704&P{PZ}l(3)0622606226 and P{PZ}dlt04276
Experimentally Determined Cytological Location
Cytogenetic map Notes References 62A1-62A1     (Freeman, 2000.11.2)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)	ru (Schulz et al., 2002)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\stet for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Added CG12083 as synonym, made it a temp to get a new CG Gene merge/split based on EST data.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) stet-RA FBtr0072713  NM_176273   1897   330 stet-RB FBtr0072712  NM_176272   2370   485
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein stet-PA   FBpp0072597   37.1   330   6.99     NP_788451   AAF47497 stet-PB   FBpp0072596   54.5   485   5.96     NP_788450   AAF47499
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • EF-HAND 2 (IPR018249) Peptidase S54, rhomboid (IPR002610) EF-hand-like domain (IPR011992) Peptidase S54, rhomboid, metazoan (IPR017213) Peptidase S54, rhomboid domain (IPR022764)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 AAF47497   AE014296 AAF47499   AF318283 AAK06752   AY119150 AAM51010   BF491389   BI357138   BI357933   BI372178   BI373155   BI484077   BI638985   BT003499 AAO39503   CK133981   CL525929   CO188368   CO188814   CO271795   CO286964   CO298728   CO318969   CO319544   CO325977   CO326084   CO340369   CO342082   CZ471727   CZ474233   CZ480539   CZ480540   CZ488532   CZ488657   CZ488658   CZ489887   CZ489888   EC071633   EC204489   EC227358   EV578615   EV585820   EV599702   GH739273   GH747745   GH749837   GH750792   GH751725   GH754824   GH759004   GH772025   GH772035   GH774953   GH777760   GH787377   GH794973   GH797050   GH798044   GH799911   GH803796   GH804228   GH805823   GH808012   GH810710   GH812936   GH815969   GH819120   GH821186   GH821996   GH822136   GH822181   GH822598   GH824396   GH825296   GH826281   GH835500   GH836755   GH837548   GH839205   GH843384   GH853689   GH855529   GH856048   GH861538   GH861913   GH865157   GH866686   GH869426   GH869822   GH870837   GH875551   GH889405   GH892386   GH895552   GH896388   GH906648   GH913025   GH915896   GH915965   GH919321   GH921073   GH921212   GH923508   GH923707   GH929514   GH936347
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q86P37 Q9BML4 Q9W0E9 Q9W0F1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0020248    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0020248 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0020248 expression level Developmental Stage   Expression Level embryo 00-02hr    2583 embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day    1672 adult female 05day    2765 adult female 30day    2703 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2583) embryo 02-04hr  103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr  (359) embryo 12-14hr  (397) embryo 14-16hr  (359) embryo 16-18hr  (158) embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new  (110) white prepupae 12hr  (152) white prepupae 24hr  (190) pupae 2d postWPP  (128) pupae 3d postWPP    38 pupae 4d postWPP  (134) adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day  (1672) adult female 05day  (2765) adult female 30day  (2703) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2583) embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day  (1672) adult female 05day  (2765) adult female 30day  (2703) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2583 embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day    1672 adult female 05day    2765 adult female 30day    2703 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2583 embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day    1672 adult female 05day    2765 adult female 30day    2703 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0020248 expression level Developmental Stage   Expression Level embryo 00-02hr    2583 embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day    1672 adult female 05day    2765 adult female 30day    2703 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2583) embryo 02-04hr  103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr  (359) embryo 12-14hr  (397) embryo 14-16hr  (359) embryo 16-18hr  (158) embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new  110 white prepupae 12hr  (152) white prepupae 24hr  (190) pupae 2d postWPP  128 pupae 3d postWPP    38 pupae 4d postWPP  134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day  (1672) adult female 05day  (2765) adult female 30day  (2703) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2583) embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day  1672 adult female 05day  (2765) adult female 30day  (2703) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2583 embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day    1672 adult female 05day    2765 adult female 30day    2703 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2583 embryo 02-04hr    103 embryo 04-06hr    54 embryo 06-08hr    44 embryo 08-10hr    94 embryo 10-12hr    359 embryo 12-14hr    397 embryo 14-16hr    359 embryo 16-18hr    158 embryo 18-20hr    73 embryo 20-22hr    52 embryo 22-24hr    50 larva L1    51 larva L2    30 larva L3 12hr old    9 larva L3 puffstage 1-2    16 larva L3 puffstage 3-6    47 larva L3 puffstage 7-9    89 white prepupae new    110 white prepupae 12hr    152 white prepupae 24hr    190 pupae 2d postWPP    128 pupae 3d postWPP    38 pupae 4d postWPP    134 adult male 01day    46 adult male 05day    67 adult male 30day    71 adult female 01day    1672 adult female 05day    2765 adult female 30day    2703 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0020248    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0020248 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0020248 expression level Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary    509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary  509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary    509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary    509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0020248 expression level Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary    509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary  509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary    509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    65.325 Larval Midgut    1.5 Larval Hindgut    3.5 Larval Malpighian Tubules    4 Larval Fat Body    8.6 Larval Salivary Gland    4.5 Larval Trachea    0.45 Larval Carcass    2.375 Adult Head    5.3 Adult Eye    4.575 Adult Brain    18.2 Adult Thoracic-Abdominal Ganglion    9.2 Adult Crop    11.4 Adult Midgut    1.1 Adult Hindgut    5 Adult Malpighian Tubules    6.7 Adult Fat Body    13 Adult Salivary Gland no informative data Adult Heart    4 Adult VirginFemale Spermatheca    8.8 Adult InseminatedFemale Spermatheca    3.4 Adult Ovary    509 Adult Testis    3.1 Adult Male Accessory Gland    4.4 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    5.3   NA  Eye    4.575   NA  Brain    18.2   65.325  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    9.2   NA  Crop    11.4   1.5  Midgut    1.1   3.5  Hindgut    5   4  Malpighian Tubules    6.7   8.6  Fat Body    13   4.5  Salivary Gland    no informative data   NA  Heart    4   0.45  Trachea    NA   NA  VirginFemale Spermatheca    8.8   NA  InseminatedFemale Spermatheca    3.4   NA  Ovary    509   NA  Testis    3.1   NA  Male Accessory Gland    4.4   2.375  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020248 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33166-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable stet1A3 stetEY07108 stetz3-0369 stetz3-0919 stetz3-2244 stetz3-3671 stetz3-3835 stetz3-4806 viable, with Scer\GAL4pnr-MD237 stetGD2244 Sterility Allele female sterile | recessive stet1A3 fertile stetEY07108 male sterile stetz3-0369 stetz3-0919 stetz3-2244 stetz3-3671 stetz3-3835 stetz3-4806 Phenotype manifest in Allele chorion, with Scer\GAL4CY2 stetScer\UAS.cGa cyst cell (with Df(3L)PX62) stet871 dorsal appendage, with Scer\GAL4CY2 stetScer\UAS.cGa egg chamber (with Df(3L)PX62) stet871 female germline stem cell (with Df(3L)PX62) stet871 germarium stet1A3 germarium | germline clone stet1A3 hub cell (with Df(3L)PX62) stet871 male germline cell stet1 male germline stem cell (with Df(3L)PX62) stet871 male germline stem cell | germline clone stetunspecified ovarian sheath cell (with Df(3L)PX62) stet871 ovariole (with Df(3L)PX62) stet871 spectrosome | germline clone | supernumerary stet1A3 spectrosome | supernumerary stet1A3 testis (with Df(3L)PX62) stet871 testis | germline clone stetunspecified wing, with Scer\GAL4Bx-MS1096 stetScer\UAS.cUa wing vein | ectopic, with Scer\GAL4Bx-MS1096 stetScer\UAS.cGa stetScer\UAS.cUa
Classical Alleles ( 26 )
For All Classical Alleles Show
Allele of stet Class Mutagen Stocks Known lesion stet5-SZ-3468 1 -- stetd00650 P-element activity 1 -- stetd04958 P-element activity 1 -- stetd05144b 1 -- stete02768 piggyBac transposase 1 -- stetEY07108 P-element activity 1 -- stetEY08201 P-element activity 1 Yes stetf05907 piggyBac transposase 1 -- stetf06018 piggyBac transposase 1 -- stet1 ethyl methanesulfonate 0 -- stet1A3 P-element activity 0 Yes stet2 ethyl methanesulfonate 0 Yes stet3 ethyl methanesulfonate 0 Yes stet871 ethyl methanesulfonate 0 Yes stet8A ethyl methanesulfonate 0 Yes stet8B ethyl methanesulfonate 0 -- stet8F ethyl methanesulfonate 0 -- stet9 ethyl methanesulfonate 0 -- stetf07112 piggyBac transposase 0 -- stetunspecified 0 -- stetz3-0369 ethyl methanesulfonate 0 Yes stetz3-0919 ethyl methanesulfonate 0 -- stetz3-2244 ethyl methanesulfonate 0 -- stetz3-3671 ethyl methanesulfonate 0 Yes stetz3-3835 ethyl methanesulfonate 0 Yes stetz3-4806 ethyl methanesulfonate 0 Yes
Alleles Carried on Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Allele of stet Class Mutagen Stocks Known lesion stetGD2244 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes steta.Scer\UAS.P\T in vitro construct - regulatory fusion 0 Yes stetAct5C.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes stetbam.PL in vitro construct - regulatory fusion 0 Yes stetdsRNA.cUa in vitro construct - RNAi 0 Yes stetScer\UAS.cGa in vitro construct - regulatory fusion 0 Yes stetScer\UAS.cSa in vitro construct - regulatory fusion 0 Yes stetScer\UAS.cUa in vitro construct - regulatory fusion 0 Yes stetScer\UAS.P\T.cGa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)29b (Schulz et al., 2002) Df(3L)PX62 (Schulz et al., 2002)
Not disrupted in	Df(3L)49-15 (Schulz et al., 2002)
Partially disrupted in	Df(3L)stet1A3 (Liu et al., 2010)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2244} NA P{UAS-stet.S} NA P{UAS-stet.U} NA characterization construct P{bam-stet.L} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}stetEY07108 NA P{EPgy2}stetEY08201 NA P{XP}stetd00650 NA P{XP}stetd04958 NA P{XP}stetd05144b NA miscellaneous insertions P{RS5}stet5-SZ-3468 NA P{SUPor-P}rhoKG07115 NA PBac{RB}stete02768 NA PBac{WH}stetf05907 NA PBac{WH}stetf06018 NA PBac{WH}stetf07112 NA insertion of enhancer trap P{lacW}W36W36 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 7 terms )
Molecular Function
CV term Evidence References
calcium ion binding inferred from electronic annotation with InterPro:IPR011992 (FlyBase Curators et al., 2004-) serine-type endopeptidase activity inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR017213, InterPro:IPR022764 (FlyBase Curators et al., 2004-) serine-type peptidase activity non-traceable author statement (Urban, 2001.10.16)
Biological Process
CV term Evidence References
epidermal growth factor receptor signaling pathway non-traceable author statement (Freeman, 2000.11.2) proteolysis inferred from electronic annotation with InterPro:IPR002610 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR002610, InterPro:IPR017213, InterPro:IPR022764 (FlyBase Curators et al., 2004-) non-traceable author statement (Urban, 2001.10.16) plasma membrane non-traceable author statement (Freeman, 2000.11.2)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions stet allele Gene References stetScer\UAS.cGa grk (Guichard et al., 2000, Ghiglione et al., 2002) S (Guichard et al., 2000) stetunspecified rho (Schulz et al., 2002)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 63709 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0020248 DroID - A comprehensive database of gene and protein interactions. • FBgn0020248 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38169
Orthologs
Genome-wide drosophilid orthologs	Dana\GF25034 Dere\GG14598 Dgri\GH15206 Dmoj\GI16724 Dper\GL22587 Dpse\GA17336 Dsec\GM14213 Dsim\GD13475 Dvir\GJ12468 Dwil\GK17206 Dyak\GE20958
Curated drosophilid orthologs	Dpse\GA17336
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001749-PA Aedes aegypti (mosquito) AGAP005058-PA Anopheles gambiae (mosquito) 275212 Branchiostoma floridae (lancelet) BGIBMGA007075-PA Bombyx mori (silk worm) ENSBTAP00000027954 Bos taurus (bovine) CN24504 Caenorhabditis brenneri (small nematode) CBP10776 Caenorhabditis briggsae (nematode) CE32392 Caenorhabditis elegans (worm) ENSCAFP00000027200 Canis familiaris (dog) ENSCINP00000013149 Ciona intestinalis (sea squirt) CPIJ003969 Culex pipens (mosquito) ENSCPOP00000016837 Cavia porcellus (guinea pig) RP21425 Caenorhabditis remanei (nematode) ENSCSAVP00000017381 Ciona savignyi (sedentary tunicate) 138117 Capitella spl (polychaete worm) 127055 Daphnia pulex (daphnia) ENSDARP00000093819 Danio rerio (zebra fish) ENSECAP00000006141 Equus caballus (horse) ENSGACP00000025655 Gymnopilus aculeatus (mushroom) ENSGALP00000005409 Gallus gallus (chicken) ENSP00000269051 Homo sapiens (human) 107360 Lottia gigantea (owl limpet) 33311 Monocosta brevicollis (choanoflagellate) ENSMODP00000023936 Monodelphis domestica (gray opossum) ENSMMUP00000004222 Macaca mulatta (rhesus monkey) ENSMUSP00000017836 Mus musculus (house mouse) XP_001607800.1 Nasonia vitripennis (wasp) ENSOANP00000015151 Ornithorynchus anatinus (platypus) ENSORLP00000004180 Oryzias latipes (japanese killifish) PHUM005029-PA Pediculus humanus (human body louse) ENSPPYP00000007836 Pongo pygmaeus (orangutan) ENSPTRP00000046891 Pan troglodytes (chimpanzee) ENSRNOP00000007312 Rattus norvegicus (norway rat) XP_001180054.1 Strongylocentrotus purpuratus (purple sea urchin) XP_969275.1 Tribolium castaneum (red flour beetle) ENSTNIP00000006321 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000031628 Takifugu rubripes (pufferfish Takifugu) 1.m00676 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000011517 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16158 PB16157 NV10350 LH11283 LH11284 FBgn0238243 FBgn0219205 FBgn0199710 FBgn0185186 FBgn0169139 JGI_V11_127055 FBgn0077349 FBgn0160178 FBgn0139472 FBgn0122681 FBgn0106854 FBgn0102026 CPIJ003969 BGIBMGA007075 ACYPI31523 ACYPI000929 GB13645 AGAP005058 AAEL001749 PHUM493270 GLEAN_06329
Stocks & Reagents
Stocks Listed in FlyBase ( 11 )
Bloomington	17375 y1 w67c23; P{EPgy2}stetEY07108 16004 y1 w67c23; P{EPgy2}stetEY08201 CG32331EY08201
Harvard	- P{XP}stetd00650 - P{XP}stetd04958 - PBac{RB}stete02768 - PBac{WH}stetf05907 - PBac{WH}stetf06018 - P{XP}d05144a, P{XP}stetd05144b
Kyoto	126078 w1118; P{RS5}stet5-SZ-3468
VDRC	v7434 w1118; P{GD2244}v7434 v7435 w1118; P{GD2244}v7435/TM3
Genomic Clones ( 1 )
	BACR27O01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 88 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE43527 RE60377
Other clones	DPiM_RE60377
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT28124 RE44565 RE45312 RE59070 RE67171 SD21404
Other clones	174446 CK01.170C.E2 Dmel_dig_015322_0631_2349 Dmel_dig_015468_0668_1295 Dmel_neb_011069_0911_1562 EK039363 EK042044 EK064428 EK104637 EK173704 EK275647 EK278852 EP03016 EP03215 EP10521 EP13804 RP001020125 RP003019870 RP003034083 RP003045147 RP003061223 RP003061225 RP003063884 RP003071883 RP003073749 RP003078822 RP003096637 RP003096856 RP003098961 RP003116740 RP003123506 RP003133323 RP003145581 RP003150072 RP003157807 RP003161556 RP003162278 RP003197337 RP003206156 RP003209047 RP003218236 RP003219353 RP003222285 RP003238673 RP003241812 RP003244163 RP003248826 RP003248945 RP003250045 RP003253562 RP003257462 RP003258643 RP003276831 RP003277070 RP003279768 RP003284167 RP003299630 RP003308282 RP003308355 RP003312186 RP003333402 RP003340402 RP003343938 RP003431882 RP003439202 RP003444710 RP003478566 RP003479107 RP003527124 RP003545042 RP003557418 RP003559954 RP003579242 RP003591724 RP003597069 RP003599433 RP003627985 RP003647567 RP003655686
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0020248 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38169
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: rho-2 CG12504 (FlyBase Genome Annotators, 2002-2003) Source for merge of: rhomboid-2 CG12083 (Wasserman et al., 2000) Source for merge of: stet rho-2 (Schulz et al., 2002)
Additional comments	3' exon of release 2 annotation CG12083 split into a new gene (CG32319) in release 3 of the genome annotation, while the 5' portion of CG12083 corresponds to part of stet (CG33166). In addition, the release 3 annotation for stet (CG33166) contains sequences corresponding to release 2 annotation CG12504. (FlyBase Genome Annotators, 2002-2003)
Other Comments
	Somatic support cells fail to surround germ cells properly and germ cells accumulate at early stages of differentiation in stet mutants. (Schulz et al., 2002) Mutations affect the early stages of differentiation in the male germline. (Schulz and Fuller, 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_176272 NM_176273 RefSeq (Proteins) • NP_788450 NP_788451 DDBJ / EMBL / GenBank • AAF47497 AAF47499 AAK06752 AAM51010 AAO39503 AF318283 AY119150 BI357138 BI373155 BT003499 CL525929 CZ471727 CZ474233 CZ480539 CZ480540 CZ488532 CZ488657 CZ488658 CZ489887 CZ489888 Entrez Gene - A searchable database of RefSeq genes. • 38169 UniProtKB/TrEMBL • Q9BML4 Q9W0E9 Q9W0F1 Q86P37
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • EF-HAND 2 (IPR018249) Peptidase S54, rhomboid (IPR002610) EF-hand-like domain (IPR011992) Peptidase S54, rhomboid, metazoan (IPR017213) Peptidase S54, rhomboid domain (IPR022764)
Linkouts
	BioGRID - A database of protein and genetic interactions • 63709 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0020248 DroID - A comprehensive database of gene and protein interactions. • FBgn0020248 DRSC - Results from RNAi screens. • FBgn0020248 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020248 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG33166-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0020248 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38169 InParanoid A subset of ortholog calls from InParanoid. • AAEL001749-PA Aedes aegypti (mosquito) AGAP005058-PA Anopheles gambiae (mosquito) 275212 Branchiostoma floridae (lancelet) BGIBMGA007075-PA Bombyx mori (silk worm) ENSBTAP00000027954 Bos taurus (bovine) CN24504 Caenorhabditis brenneri (small nematode) CBP10776 Caenorhabditis briggsae (nematode) CE32392 Caenorhabditis elegans (worm) ENSCAFP00000027200 Canis familiaris (dog) ENSCINP00000013149 Ciona intestinalis (sea squirt) CPIJ003969 Culex pipens (mosquito) ENSCPOP00000016837 Cavia porcellus (guinea pig) RP21425 Caenorhabditis remanei (nematode) ENSCSAVP00000017381 Ciona savignyi (sedentary tunicate) 138117 Capitella spl (polychaete worm) 127055 Daphnia pulex (daphnia) ENSDARP00000093819 Danio rerio (zebra fish) ENSECAP00000006141 Equus caballus (horse) ENSGACP00000025655 Gymnopilus aculeatus (mushroom) ENSGALP00000005409 Gallus gallus (chicken) ENSP00000269051 Homo sapiens (human) 107360 Lottia gigantea (owl limpet) 33311 Monocosta brevicollis (choanoflagellate) ENSMODP00000023936 Monodelphis domestica (gray opossum) ENSMMUP00000004222 Macaca mulatta (rhesus monkey) ENSMUSP00000017836 Mus musculus (house mouse) XP_001607800.1 Nasonia vitripennis (wasp) ENSOANP00000015151 Ornithorynchus anatinus (platypus) ENSORLP00000004180 Oryzias latipes (japanese killifish) PHUM005029-PA Pediculus humanus (human body louse) ENSPPYP00000007836 Pongo pygmaeus (orangutan) ENSPTRP00000046891 Pan troglodytes (chimpanzee) ENSRNOP00000007312 Rattus norvegicus (norway rat) XP_001180054.1 Strongylocentrotus purpuratus (purple sea urchin) XP_969275.1 Tribolium castaneum (red flour beetle) ENSTNIP00000006321 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000031628 Takifugu rubripes (pufferfish Takifugu) 1.m00676 Tetrahymena thermophila (ciliate protozoa) ENSXETP00000011517 Xenopus tropicalis (frog) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /torstoll/rhombd2-1.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38169 modMine - Data generated by the modENCODE project. • FBgn0020248 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16158 PB16157 NV10350 LH11283 LH11284 FBgn0238243 FBgn0219205 FBgn0199710 FBgn0185186 FBgn0169139 JGI_V11_127055 FBgn0077349 FBgn0160178 FBgn0139472 FBgn0122681 FBgn0106854 FBgn0102026 CPIJ003969 BGIBMGA007075 ACYPI31523 ACYPI000929 GB13645 AGAP005058 AAEL001749 PHUM493270 GLEAN_06329
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	Brho (Shilo, 2003) brho (Ghiglione et al., 2002, Guichard et al., 2000) B-Rho (Castro et al., 2007) CG12083 (Kai et al., 2005, ) CG12504   CG33166   Rho2 (Shilo, 2003) Rho-2 (Urban et al., 2002, Yogev et al., 2007, Yogev et al., 2008, Yogev et al., 2008) rho-2 (Wasserman et al., 2000, Giot et al., 2003, Dworkin and Gibson, 2006, Jiang and Edgar, 2009) rho2 (Jiang et al., 2011) stet (Fuller and Spradling, 2007, Parrott et al., 2011, Yamashita et al., 2005, Xie et al., 2005, Kitadate and Kobayashi, 2010, Liu et al., 2010, Jiang and Edgar, 2009)
Name Synonym	brother of rhomboid (Guichard et al., 2000) rhomboid-2 (Urban et al., 2004, Klambt, 2000, Urban and Freeman, 2003, Wasserman et al., 2000, Dworkin and Gibson, 2006, Urban, 2006) stem cell tumor (Schulz and Fuller, 1997, Castro et al., 2007) Stem cell tumor (Liu et al., 2010)
Secondary FlyBase IDs
	FBgn0035221 FBgn0035223 FBgn0041725 FBgn0053166
References ( 47 )
Generate a list of	All references relating to this gene ( 47 )
List References by type	Research paper  ( 17 ) Supplementary material  ( 3 ) Review  ( 8 ) Personal communication to FlyBase  ( 3 ) Abstract  ( 7 ) FlyBase analysis  ( 4 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 4 )
	Jiang et al., 2011, Cell Stem Cell 8(1): 84--95 EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila. [FBrf0212694] Parrott et al., 2011, PLoS ONE 6(9): e25087 Nucleoporin98-96 Function Is Required for Transit Amplification Divisions in the Germ Line of Drosophila melanogaster. [FBrf0216255] Kitadate and Kobayashi, 2010, Proc. Natl. Acad. Sci. U.S.A. 107(32): 14241--14246 Notch and Egfr signaling act antagonistically to regulate germ-line stem cell niche formation in Drosophila male embryonic gonads. [FBrf0211513] Liu et al., 2010, Sci. Signal. 3(132): ra57 The Drosophila Female Germline Stem Cell Lineage Acts to Spatially Restrict DPP Function Within the Niche. [FBrf0211426] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...