Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.51
None of the polypeptides share 100% sequence identity.
Component of the Tip60 chromatin-remodeling complex which contains Domino, Tip60, Tra1, Brd8, E(Pc), DMAP1, Pontin, Reptin, Ing3, Act87E, BAP55, Mrg15, MrgBP, Gas41 and YL-1.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dom using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\dom in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The dom A and B protein isoforms have non-redundant functions in the germline and soma for egg formation. DOM-A promotes the removal of His2Av protein from stage 5 nurse cells, whereas DOM-B is required for chromatin incorporation of His2Av protein in germline and somatic cells.
dsRNA made from templates generated with primers directed against this gene was tested in an RNAi screen to identify genes that regulate Ca2+ release.
The dom products function as global transcriptional regulators via interactions with heterochromatin.
Gene isolated in a screen of the second chromosome identifying mutants affecting disc morphology.