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Gene Dmel\Idgf2

General Information
Symbol	Dmel\Idgf2	Species	D. melanogaster
Name	Imaginal disc growth factor 2	Annotation symbol	CG4475
Feature type	protein_coding_gene	FlyBase ID	FBgn0020415
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	BG:DS02780.4, IDGF
Genomic Location
Chromosome (arm)	2L	Recombination map	2-
Cytogenetic map	36A1-36A1	Sequence location	2L:16,447,330..16,450,508 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Imaginal disc growth factor 2 is referred to in FlyBase by the symbol Dmel\Idgf2 (CG4475, FBgn0020415). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: imaginal disc growth factor receptor binding. There is experimental evidence that it is involved in the biological process: imaginal disc development. 4 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Chitinase II; Glycoside hydrolase, catalytic domain; Glycoside hydrolase, family 18, catalytic domain; Glycoside hydrolase, superfamily; Imaginal disc growth factor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult hindgut, adult heart, larval/adult fat body, larval trachea, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult salivary gland, adult ovary, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1640202_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Idgf2. Gene sequence location is 2L:16447330..16450508.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 36A1-36A1   Limits computationally determined from genome sequence between P{EP}fzyEP1028&P{lacW}mRpL4k14608 and P{PZ}dacP
Experimentally Determined Cytological Location
Cytogenetic map Notes References 36A2-36A4     (Kawamura, 1998.10.28) 36A2-36A4     (Kawamura et al., 1997)
Experimentally Determined Recombination Data
Location	2- (Kawamura et al., 1997)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Idgf2 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50 Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Idgf2-RA FBtr0080861  NM_057909   1440   440 Idgf2-RB FBtr0305984  NM_001259114   1796   368 Idgf2-RC FBtr0308080  NM_001259113   1367   368
Additional Transcript Data & Comments
Reported size (kB)	1.390 (longest cDNA) (Kawamura et al., 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Idgf2-PA   FBpp0080418   49.2   440   6.52     NP_477257   AAF53536 Idgf2-PB   FBpp0297126   41.1   368   6.80     NP_001246043   AFH03717 Idgf2-PC   FBpp0300423   41.1   368   6.80     NP_001246042   AFH03716
Additional Polypeptide Data & Comments
Reported size (kDa)	440 (aa) (Kawamura et al., 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Glycoside hydrolase, family 18, catalytic domain (IPR001223) Chitinase II (IPR011583) Imaginal disc growth factor (IPR015520) Glycoside hydrolase, catalytic domain (IPR013781) Glycoside hydrolase, superfamily (IPR017853) PDB - Protein Data Bank. An information portal to biological macromolecular structures • 1JND 1JNE
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA697525   AE014134 AAF53536   AE003416 AAF45017   AF102237 AAC99418   AE014134 AFH03716   AE014134 AFH03717   AI062770   AI062846   AI106583   AI107384   AI107713   AI108757   AI113764   AI134724   AI134980   AI239042   AI257312   AI295560   AI296817   AI387624   AI405284   AY060686 AAL28234   BI170903   BI578353   BI636163   BI636690   BI641703   BP554019   BP556932   BP556933   BT122063   BT124776   CA807607   CO178190   CO183742   CO186890   CO265961   CO266902   CO287376   CO299805   CO324803   CO327361   CO327852   CO328888   CO331983   CO337069   EC063397   EC069730   EC081180   EC198991   EC217682   EC232788   EC251078   EC256989   EC258045   EC261507   EV591193   EV597364   EV600324   GH756111   GH757551   GH760741   GH778324   GH778971   GH781918   GH797210   GH800795   GH805039   GH806276   GH806821   GH806955   GH807955   GH817525   GH819195   GH819366   GH821168   GH823139   GH825596   GH826728   GH827857   GH841774   GH848373   GH866816   GH875075   GH880500   GH883245   GH883512   GH883894   GH886276   GH888442   GH894370   GH895244   GH895469   GH904704   GH911164   GH918193   GH924875   GH933232   GH936425   GH937113   GH938307   GH940288
UniProtKB/Swiss-Prot	Q9V3D4
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference embryonic stage   ventral furrow | vicinity of   (Kawamura et al., 1999) amnioproctodeal invagination | vicinity of   (Kawamura et al., 1999) embryonic stage & larval stage   embryonic/larval salivary gland   (Kawamura et al., 1999) third instar larval stage   embryonic/larval brain   (Kawamura et al., 1999) ring gland   (Kawamura et al., 1999) imaginal disc   (Kawamura et al., 1999) adult stage & oogenesis   oocyte   (Kawamura et al., 1999) in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage   cephalic furrow | vicinity of   (Kawamura et al., 1999) embryonic/larval tracheal system   (Kawamura et al., 1999) yolk   (Kawamura et al., 1999) embryonic stage & larval stage   embryonic/larval fat body   (Kawamura et al., 1999) embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | faint & ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   head mesoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   head mesoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic/larval fat body   (Fisher et al., 2012) embryonic/larval lymph gland   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012) third instar larval stage   embryonic/larval optic lobe   (Kawamura et al., 1999) embryonic/larval lymph gland   (Kawamura et al., 1999) adult stage & oogenesis   nurse cell   (Kawamura et al., 1999)
Additional Descriptive Data
	Idgf2 transcripts are expressed at all stages tested on northern blots but most heavily in mid-larval stages. Idgf2 transcripts are present in the yolk cytoplasm in the early embryo but are excluded from the blastoderm as it cellularizes. During gastrulation, transcripts are observed in rows parallel to the major invaginations including the ventral furrow, the cephalic furrow, and the anterior and posterior midgut invaginations. In late embryos, Idgf2 transcripts are observed in yolk cells, fat body, salivary glands, and in the tracheal system. In third instar larvae, Idgf2 transcripts are strongly expressed in fat body, the ring gland, and in lymph glands. Expression is also observed in the optic lobes, the central brain, and in imaginal discs. Duing oogenesis, Idgf2 transcripts are present in nurse cells and in the oocyte. While the patterns of expression of the four Idgf genes are in general very similar, they are differentially expressed in the larval salivary glands. Levels of Idgf2 and Idgf4 are generally higher than Idgf1 and Idgf3. (Kawamura et al., 1999)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
extracellular region inferred from direct assay (Karlsson et al., 2004) inferred from direct assay (assigned by UniProtKB) (Kawamura et al., 1999)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult hindgut, adult heart, larval/adult fat body, larval trachea, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult salivary gland, adult ovary, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut    875.7 Larval Malpighian Tubules    22.7 Larval Fat Body    2034.7 Larval Salivary Gland    71.8 Larval Trachea    1181.5 Larval Carcass    440.825 Adult Head    1436.1 Adult Eye    917.5 Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop    804.9 Adult Midgut    37.1 Adult Hindgut    1072.8 Adult Malpighian Tubules    56.2 Adult Fat Body    2556.7 Adult Salivary Gland    133.2 Adult Heart    2576.875 Adult VirginFemale Spermatheca    1891.6 Adult InseminatedFemale Spermatheca    1575.2 Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass    1607.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut  (875.7) Larval Malpighian Tubules    22.7 Larval Fat Body  (2034.7) Larval Salivary Gland    71.8 Larval Trachea  (1181.5) Larval Carcass    440.825 Adult Head  (1436.1) Adult Eye  (917.5) Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop  (804.9) Adult Midgut    37.1 Adult Hindgut  (1072.8) Adult Malpighian Tubules    56.2 Adult Fat Body  (2556.7) Adult Salivary Gland    133.2 Adult Heart  (2576.875) Adult VirginFemale Spermatheca  (1891.6) Adult InseminatedFemale Spermatheca  (1575.2) Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass  (1607.5) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut    875.7 Larval Malpighian Tubules    22.7 Larval Fat Body  (2034.7) Larval Salivary Gland    71.8 Larval Trachea  (1181.5) Larval Carcass    440.825 Adult Head  (1436.1) Adult Eye    917.5 Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop    804.9 Adult Midgut    37.1 Adult Hindgut  1072.8 Adult Malpighian Tubules    56.2 Adult Fat Body  (2556.7) Adult Salivary Gland    133.2 Adult Heart  (2576.875) Adult VirginFemale Spermatheca  (1891.6) Adult InseminatedFemale Spermatheca  (1575.2) Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass  (1607.5) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut    875.7 Larval Malpighian Tubules    22.7 Larval Fat Body    2034.7 Larval Salivary Gland    71.8 Larval Trachea    1181.5 Larval Carcass    440.825 Adult Head    1436.1 Adult Eye    917.5 Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop    804.9 Adult Midgut    37.1 Adult Hindgut    1072.8 Adult Malpighian Tubules    56.2 Adult Fat Body    2556.7 Adult Salivary Gland    133.2 Adult Heart    2576.875 Adult VirginFemale Spermatheca    1891.6 Adult InseminatedFemale Spermatheca    1575.2 Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass    1607.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut    875.7 Larval Malpighian Tubules    22.7 Larval Fat Body    2034.7 Larval Salivary Gland    71.8 Larval Trachea    1181.5 Larval Carcass    440.825 Adult Head    1436.1 Adult Eye    917.5 Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop    804.9 Adult Midgut    37.1 Adult Hindgut    1072.8 Adult Malpighian Tubules    56.2 Adult Fat Body    2556.7 Adult Salivary Gland    133.2 Adult Heart    2576.875 Adult VirginFemale Spermatheca    1891.6 Adult InseminatedFemale Spermatheca    1575.2 Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass    1607.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut  (875.7) Larval Malpighian Tubules    22.7 Larval Fat Body  (2034.7) Larval Salivary Gland    71.8 Larval Trachea  (1181.5) Larval Carcass    440.825 Adult Head  (1436.1) Adult Eye  (917.5) Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop  804.9 Adult Midgut    37.1 Adult Hindgut  (1072.8) Adult Malpighian Tubules    56.2 Adult Fat Body  (2556.7) Adult Salivary Gland    133.2 Adult Heart  (2576.875) Adult VirginFemale Spermatheca  (1891.6) Adult InseminatedFemale Spermatheca  (1575.2) Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass  (1607.5) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut    875.7 Larval Malpighian Tubules    22.7 Larval Fat Body  (2034.7) Larval Salivary Gland    71.8 Larval Trachea  1181.5 Larval Carcass    440.825 Adult Head  1436.1 Adult Eye    917.5 Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop    804.9 Adult Midgut    37.1 Adult Hindgut  1072.8 Adult Malpighian Tubules    56.2 Adult Fat Body  (2556.7) Adult Salivary Gland    133.2 Adult Heart  (2576.875) Adult VirginFemale Spermatheca  (1891.6) Adult InseminatedFemale Spermatheca  1575.2 Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass  1607.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    120.575 Larval Midgut    38.2 Larval Hindgut    875.7 Larval Malpighian Tubules    22.7 Larval Fat Body    2034.7 Larval Salivary Gland    71.8 Larval Trachea    1181.5 Larval Carcass    440.825 Adult Head    1436.1 Adult Eye    917.5 Adult Brain    141 Adult Thoracic-Abdominal Ganglion    212.9 Adult Crop    804.9 Adult Midgut    37.1 Adult Hindgut    1072.8 Adult Malpighian Tubules    56.2 Adult Fat Body    2556.7 Adult Salivary Gland    133.2 Adult Heart    2576.875 Adult VirginFemale Spermatheca    1891.6 Adult InseminatedFemale Spermatheca    1575.2 Adult Ovary    272.2 Adult Testis    74.6 Adult Male Accessory Gland    22 Adult Carcass    1607.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1436.1   NA  Eye    917.5   NA  Brain    141   120.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    212.9   NA  Crop    804.9   38.2  Midgut    37.1   875.7  Hindgut    1072.8   22.7  Malpighian Tubules    no informative data   2034.7  Fat Body    2556.7   71.8  Salivary Gland    133.2   NA  Heart    2576.875   1181.5  Trachea    NA   NA  VirginFemale Spermatheca    1891.6   NA  InseminatedFemale Spermatheca    1575.2   NA  Ovary    272.2   NA  Testis    74.6   NA  Male Accessory Gland    no informative data   440.825  Carcass    1607.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female    44 head, virgin 4-day female    54 head, virgin 20-day female    148 head, mated 1-day female    34 head, mated 4-day female    70 head, mated 20-day female    102 head, mated 1-day male    38 head, mated 4-day male    64 head, mated 20-day male    118 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering    48 fat body, white prepupae    115 fat body, pupae P8    37 carcass, larvae L3 wandering    20 carcass, 1-day adult    49 carcass, 4-day adult    63 carcass, 20-day adult    81 ovary, virgin 4-day female    46 ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female  (44) head, virgin 4-day female  (54) head, virgin 20-day female  (148) head, mated 1-day female  (34) head, mated 4-day female  (70) head, mated 20-day female  (102) head, mated 1-day male  (38) head, mated 4-day male  (64) head, mated 20-day male  (118) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering  (48) fat body, white prepupae  (115) fat body, pupae P8  (37) carcass, larvae L3 wandering    20 carcass, 1-day adult  (49) carcass, 4-day adult  (63) carcass, 20-day adult  (81) ovary, virgin 4-day female  (46) ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female    44 head, virgin 4-day female    54 head, virgin 20-day female  (148) head, mated 1-day female    34 head, mated 4-day female    70 head, mated 20-day female  102 head, mated 1-day male    38 head, mated 4-day male    64 head, mated 20-day male  (118) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering    48 fat body, white prepupae  (115) fat body, pupae P8    37 carcass, larvae L3 wandering    20 carcass, 1-day adult    49 carcass, 4-day adult    63 carcass, 20-day adult    81 ovary, virgin 4-day female    46 ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female    44 head, virgin 4-day female    54 head, virgin 20-day female    148 head, mated 1-day female    34 head, mated 4-day female    70 head, mated 20-day female    102 head, mated 1-day male    38 head, mated 4-day male    64 head, mated 20-day male    118 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering    48 fat body, white prepupae    115 fat body, pupae P8    37 carcass, larvae L3 wandering    20 carcass, 1-day adult    49 carcass, 4-day adult    63 carcass, 20-day adult    81 ovary, virgin 4-day female    46 ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female    44 head, virgin 4-day female    54 head, virgin 20-day female    148 head, mated 1-day female    34 head, mated 4-day female    70 head, mated 20-day female    102 head, mated 1-day male    38 head, mated 4-day male    64 head, mated 20-day male    118 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering    48 fat body, white prepupae    115 fat body, pupae P8    37 carcass, larvae L3 wandering    20 carcass, 1-day adult    49 carcass, 4-day adult    63 carcass, 20-day adult    81 ovary, virgin 4-day female    46 ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female  (44) head, virgin 4-day female  (54) head, virgin 20-day female  (148) head, mated 1-day female  (34) head, mated 4-day female  (70) head, mated 20-day female  (102) head, mated 1-day male  (38) head, mated 4-day male  (64) head, mated 20-day male  (118) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering  (48) fat body, white prepupae  (115) fat body, pupae P8  (37) carcass, larvae L3 wandering    20 carcass, 1-day adult  (49) carcass, 4-day adult  (63) carcass, 20-day adult  (81) ovary, virgin 4-day female  (46) ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female    44 head, virgin 4-day female    54 head, virgin 20-day female  (148) head, mated 1-day female    34 head, mated 4-day female    70 head, mated 20-day female  102 head, mated 1-day male    38 head, mated 4-day male    64 head, mated 20-day male  118 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering    48 fat body, white prepupae  115 fat body, pupae P8    37 carcass, larvae L3 wandering    20 carcass, 1-day adult    49 carcass, 4-day adult    63 carcass, 20-day adult    81 ovary, virgin 4-day female    46 ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    7 central nervous system, pupae P8    3 head, virgin 1-day female    44 head, virgin 4-day female    54 head, virgin 20-day female    148 head, mated 1-day female    34 head, mated 4-day female    70 head, mated 20-day female    102 head, mated 1-day male    38 head, mated 4-day male    64 head, mated 20-day male    118 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    10 digestive system, larvae L3 wandering    7 digestive system, 1-day adult    13 digestive system, 4-day adult    10 digestive system, 20-day adult    10 fat body, larvae L3 wandering    48 fat body, white prepupae    115 fat body, pupae P8    37 carcass, larvae L3 wandering    20 carcass, 1-day adult    49 carcass, 4-day adult    63 carcass, 20-day adult    81 ovary, virgin 4-day female    46 ovary, mated 4-day female    24 testis, mated 4-day male    7 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr    38 embryo 14-16hr    66 embryo 16-18hr    105 embryo 18-20hr    142 embryo 20-22hr    139 embryo 22-24hr    163 larva L1    88 larva L2    67 larva L3 12hr old    112 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    35 larva L3 puffstage 7-9    35 white prepupae new    33 white prepupae 12hr    77 white prepupae 24hr    33 pupae 2d postWPP    36 pupae 3d postWPP    82 pupae 4d postWPP    132 adult male 01day    46 adult male 05day    46 adult male 30day    37 adult female 01day    28 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr  (38) embryo 14-16hr  (66) embryo 16-18hr  (105) embryo 18-20hr  (142) embryo 20-22hr  (139) embryo 22-24hr  (163) larva L1  (88) larva L2  (67) larva L3 12hr old  (112) larva L3 puffstage 1-2  (55) larva L3 puffstage 3-6  (35) larva L3 puffstage 7-9  (35) white prepupae new  (33) white prepupae 12hr  (77) white prepupae 24hr  (33) pupae 2d postWPP  (36) pupae 3d postWPP  (82) pupae 4d postWPP  (132) adult male 01day  (46) adult male 05day  (46) adult male 30day  (37) adult female 01day  (28) adult female 05day  (31) adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr    38 embryo 14-16hr    66 embryo 16-18hr  105 embryo 18-20hr  (142) embryo 20-22hr  (139) embryo 22-24hr  (163) larva L1    88 larva L2    67 larva L3 12hr old  (112) larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    35 larva L3 puffstage 7-9    35 white prepupae new    33 white prepupae 12hr    77 white prepupae 24hr    33 pupae 2d postWPP    36 pupae 3d postWPP    82 pupae 4d postWPP  (132) adult male 01day    46 adult male 05day    46 adult male 30day    37 adult female 01day    28 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr    38 embryo 14-16hr    66 embryo 16-18hr    105 embryo 18-20hr    142 embryo 20-22hr    139 embryo 22-24hr    163 larva L1    88 larva L2    67 larva L3 12hr old    112 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    35 larva L3 puffstage 7-9    35 white prepupae new    33 white prepupae 12hr    77 white prepupae 24hr    33 pupae 2d postWPP    36 pupae 3d postWPP    82 pupae 4d postWPP    132 adult male 01day    46 adult male 05day    46 adult male 30day    37 adult female 01day    28 adult female 05day    31 adult female 30day    33 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr    38 embryo 14-16hr    66 embryo 16-18hr    105 embryo 18-20hr    142 embryo 20-22hr    139 embryo 22-24hr    163 larva L1    88 larva L2    67 larva L3 12hr old    112 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    35 larva L3 puffstage 7-9    35 white prepupae new    33 white prepupae 12hr    77 white prepupae 24hr    33 pupae 2d postWPP    36 pupae 3d postWPP    82 pupae 4d postWPP    132 adult male 01day    46 adult male 05day    46 adult male 30day    37 adult female 01day    28 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr  (38) embryo 14-16hr  (66) embryo 16-18hr  (105) embryo 18-20hr  (142) embryo 20-22hr  (139) embryo 22-24hr  (163) larva L1  (88) larva L2  (67) larva L3 12hr old  (112) larva L3 puffstage 1-2  (55) larva L3 puffstage 3-6  (35) larva L3 puffstage 7-9  (35) white prepupae new  (33) white prepupae 12hr  (77) white prepupae 24hr  (33) pupae 2d postWPP  (36) pupae 3d postWPP  (82) pupae 4d postWPP  (132) adult male 01day  (46) adult male 05day  (46) adult male 30day  (37) adult female 01day  28 adult female 05day  31 adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr    38 embryo 14-16hr    66 embryo 16-18hr  105 embryo 18-20hr  142 embryo 20-22hr  139 embryo 22-24hr  (163) larva L1    88 larva L2    67 larva L3 12hr old  112 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    35 larva L3 puffstage 7-9    35 white prepupae new    33 white prepupae 12hr    77 white prepupae 24hr    33 pupae 2d postWPP    36 pupae 3d postWPP    82 pupae 4d postWPP  132 adult male 01day    46 adult male 05day    46 adult male 30day    37 adult female 01day    28 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6 embryo 02-04hr    6 embryo 04-06hr    10 embryo 06-08hr    6 embryo 08-10hr    11 embryo 10-12hr    22 embryo 12-14hr    38 embryo 14-16hr    66 embryo 16-18hr    105 embryo 18-20hr    142 embryo 20-22hr    139 embryo 22-24hr    163 larva L1    88 larva L2    67 larva L3 12hr old    112 larva L3 puffstage 1-2    55 larva L3 puffstage 3-6    35 larva L3 puffstage 7-9    35 white prepupae new    33 white prepupae 12hr    77 white prepupae 24hr    33 pupae 2d postWPP    36 pupae 3d postWPP    82 pupae 4d postWPP    132 adult male 01day    46 adult male 05day    46 adult male 30day    37 adult female 01day    28 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    36 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1    121 embryonic S3    8 leg disc CME L1    4 wing disc CME-W2    94 wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    78 wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    61 mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    241 ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (36) Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1  (121) embryonic S3    8 leg disc CME L1    4 wing disc CME-W2  (94) wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3  (78) wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  (114) antennal disc ML-DmD20-c5  (61) mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2  (241) ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    36 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1  (121) embryonic S3    8 leg disc CME L1    4 wing disc CME-W2    94 wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    78 wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  (114) antennal disc ML-DmD20-c5    61 mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2  (241) ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    36 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1    121 embryonic S3    8 leg disc CME L1    4 wing disc CME-W2    94 wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    78 wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    61 mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    241 ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    36 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1    121 embryonic S3    8 leg disc CME L1    4 wing disc CME-W2    94 wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    78 wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    61 mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    241 ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (36) Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1  (121) embryonic S3    8 leg disc CME L1    4 wing disc CME-W2  (94) wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3  (78) wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  (114) antennal disc ML-DmD20-c5  (61) mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2  (241) ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    36 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1  121 embryonic S3    8 leg disc CME L1    4 wing disc CME-W2    94 wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    78 wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11  114 antennal disc ML-DmD20-c5    61 mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2  (241) ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    36 Schneider line 2 Sg4    4 embryonic 1182-4H    4 embryonic GM2    15 embryonic Kc167    14 embryonic S1    121 embryonic S3    8 leg disc CME L1    4 wing disc CME-W2    94 wing disc ML-DmD8    5 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    78 wing disc ML-DmD21    1 wing disc ML-DmD32    23 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    114 antennal disc ML-DmD20-c5    61 mixed discs ML-DmD4-c1    22 CNS ML-DmBG1-c1    9 CNS ML-DmBG2-c2    4 tumorous blood cells mbn2    241 ovary fGS/OSS    3 ovary OSC    3 ovary OSS    5 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    41 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    59 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    67 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    35 Paraquat 10 mM 48 hrs, 4-day adult    39 Rotenone 2 μg 12 hrs, larvae L3    52 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3  (31) Cadmium 50 mM 12 hrs, larvae L3  (42) Cadmium 50 mM 48 hrs, 4-day adult  (41) Cadmium 100 mM 48 hrs, 4-day adult  26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult  (28) Ethanol 2.5% 3 hrs, larvae L3  (34) Ethanol 5% 3 hrs, larvae L3  (59) Ethanol 10% 3 hrs, larvae L3  (39) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (67) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult  (35) Paraquat 10 mM 48 hrs, 4-day adult  (39) Rotenone 2 μg 12 hrs, larvae L3  (52) Rotenone 8 μg 12 hrs, larvae L3  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    41 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    59 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    67 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    35 Paraquat 10 mM 48 hrs, 4-day adult    39 Rotenone 2 μg 12 hrs, larvae L3    52 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    41 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    59 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    67 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    35 Paraquat 10 mM 48 hrs, 4-day adult    39 Rotenone 2 μg 12 hrs, larvae L3    52 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    41 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    59 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    67 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    35 Paraquat 10 mM 48 hrs, 4-day adult    39 Rotenone 2 μg 12 hrs, larvae L3    52 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3  31 Cadmium 50 mM 12 hrs, larvae L3  (42) Cadmium 50 mM 48 hrs, 4-day adult  (41) Cadmium 100 mM 48 hrs, 4-day adult  26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult  28 Ethanol 2.5% 3 hrs, larvae L3  (34) Ethanol 5% 3 hrs, larvae L3  (59) Ethanol 10% 3 hrs, larvae L3  (39) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (67) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (38) Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult  (35) Paraquat 10 mM 48 hrs, 4-day adult  (39) Rotenone 2 μg 12 hrs, larvae L3  (52) Rotenone 8 μg 12 hrs, larvae L3  (35) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    41 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    59 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    67 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    35 Paraquat 10 mM 48 hrs, 4-day adult    39 Rotenone 2 μg 12 hrs, larvae L3    52 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    7 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    31 Cadmium 50 mM 12 hrs, larvae L3    42 Cadmium 50 mM 48 hrs, 4-day adult    41 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    6 Copper 15 mM 48 hrs, 4-day adult    21 Zinc 5 mM 12 hrs, larvae L3    10 Zinc 4.5 mM 48 hrs, 4-day adult    28 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    59 Ethanol 10% 3 hrs, larvae L3    39 Caffeine 1.5 mg/ml 4 hrs, larvae L3    67 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    38 Caffeine 25 mg/ml 48 hrs, 4-day adult    11 Paraquat 5 mM 48 hrs, 4-day adult    35 Paraquat 10 mM 48 hrs, 4-day adult    39 Rotenone 2 μg 12 hrs, larvae L3    52 Rotenone 8 μg 12 hrs, larvae L3    35 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_15
External Data & Images
Linkouts	BDGP expression data • CG4475 GH12581 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020415 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4475-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Idgf2 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of Idgf2 Class Mutagen Stocks Known lesion Idgf2e02257 2 -- Idgf2Roi-Rev P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Idgf2 Class Mutagen Stocks Known lesion Idgf2GD5406 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes Idgf2NIG.4475R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7065 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5406} NA P{NIG.4475R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{}Idgf2Roi-Rev NA PBac{RB}CG5888e02257 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function
CV term Evidence References
imaginal disc growth factor receptor binding inferred from direct assay (Kawamura et al., 1997) inferred from direct assay (assigned by UniProtKB) (Kawamura et al., 1999)
Biological Process
CV term Evidence References
imaginal disc development inferred from direct assay (assigned by UniProtKB) (Kawamura et al., 1999)
Cellular Component
CV term Evidence References
extracellular region inferred from direct assay (Karlsson et al., 2004) inferred from direct assay (assigned by UniProtKB) (Kawamura et al., 1999)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
NOT chitinase activity inferred from sequence or structural similarity (assigned by UniProtKB) (Kawamura et al., 1999) chitinase activity inferred from electronic annotation with InterPro:IPR011583 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
carbohydrate metabolic process inferred from electronic annotation with InterPro:IPR001223, InterPro:IPR013781 (FlyBase Curators et al., 2004-) chitin catabolic process inferred from electronic annotation with InterPro:IPR011583 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Idgf2 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60988 DroID - A comprehensive database of gene and protein interactions. • FBgn0020415 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34979
Orthologs
OrthoDB Orthologs (33) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6M39VD Dipteran inclusive ortholog search EOG6TF0TN Insect inclusive ortholog search EOG6B5N1J Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6M39VD)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Idgf2     Drosophila simulans   Dsim\GD24057 Y   Drosophila sechellia   Dsec\GM17178 Y   Drosophila erecta   Dere\GG22749 Y   Drosophila yakuba   Dyak\GE13108 Y   Drosophila ananassae   Dana\GF13994 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18210 Y   Drosophila persimilis   Dper\GL19638 Y   Drosophila willistoni   Dwil\GK24710 Y   Drosophila virilis   Dvir\GJ22638 Y   Drosophila mojavensis   Dmoj\GI17259 Y   Drosophila grimshawi   Dgri\GH25190 Y
Orthologs in non-Drosophila Dipterans (EOG6TF0TN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL001965 Y Aedes aegypti Yellow fever mosquito  Aaeg\AAEL002023 Y Anopheles gambiae Malaria mosquito  Agam\AGAP008060 Y Anopheles gambiae Malaria mosquito  Agam\AGAP008061 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802014 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802013 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802015 Y
Orthologs in non-Dipteran Insects (EOG6B5N1J)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB52829 Y Apis mellifera Western honey bee  Amel\GB48505 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG024747 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21020 Y Atta cephalotes Leafcutter ant  Acep\ACEP16941 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21654 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20220 Y Linepithema humile Argentine ant  Lhum\LH20042 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16624 Y Solenopsis invicta Red fire ant  Sinv\SINV24111 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001365 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000648 Y Tribolium castaneum Red flour beetle  Tcas\TC013918 Y Tribolium castaneum Red flour beetle  Tcas\TC013917 Y
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24057 Drosophila sechellia Dsec\GM17178 Drosophila erecta Dere\GG22749 Drosophila yakuba Dyak\GE13108 Drosophila ananassae Dana\GF13994 Drosophila pseudoobscura pseudoobscura Dpse\GA18210 Drosophila persimilis Dper\GL19638 Drosophila willistoni Dwil\GK24710 Drosophila virilis Dvir\GJ22638 Drosophila mojavensis Dmoj\GI17259 Drosophila grimshawi Dgri\GH25190
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
Bloomington	18031 w1118; PBac{RB}CG5888e02257 Idgf2e02257/CyO
Kyoto	114499 yd2 w1118 P{ey-FLP.N}2; PBac{RB}CG5888e02257 Idgf2e02257 P{neoFRT}40A/CyO y+
Genomic Clones ( 2 )
	BACR01N08 BACR33A07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 94 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH12581
Other clones	MIP18369 MIP21791
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH02092 GH02192 GH04196 GH05540 GH06632 GH07990 GH10214 GH12262 GH15212 GH18193 GH25237 HL02712 LP05630 LP09232 LP10907 RE12518 RE72218 SD17752 SD18471 SD25254
Other clones	27997 34532 66974 214217.29 214217.30 274616 562129 CK01.23B.E2 CK01.69C.H12 Dmel_neb_008832_0858_3376 Dmel_neb_010340_0949_3429 Dmel_neb_011096_0404_0452 EC26244 EK024437 EK055662 EK065662 EK144557 EK147903 EK176552 EK194859 EK291613 EK302234 EN13757 EP06839 EP08139 ESG018c.E21_G09 FGM227E09 FGM306D03 RP003030884 RP003033988 RP003040110 RP003054918 RP003084572 RP003178006 RP003189018 RP003216150 RP003218709 RP003219210 RP003234871 RP003239487 RP003244529 RP003261168 RP003264078 RP003274629 RP003281150 RP003293627 RP003307807 RP003308174 RP003312884 RP003324361 RP003327239 RP003356884 RP003373239 RP003461696 RP003463489 RP003471617 RP003497851 RP003509366 RP003539242 RP003542941 RP003550596 RP003552285 RP003557327 RP003578723 RP003592607 RP003629774 RP003631649 RP003638211 RP003647540 RP003654371 RP003681338
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0020415 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34979
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Idgf2 CG4475 (Zhong, 1999.11)
Source for database merge of
Additional comments
Other Comments
	Maps to subclone 9-a11 of P1 DS02780. (Kawamura et al., 1999) Candidate gene for tibia length quantitative trait locus. (Macdonald and Goldstein, 1999) Encodes a soluble growth factor that works in combination with insulin to stimulate cell proliferation, cell polarisation and movement. (Kawamura et al., 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057909 NM_001259113 NM_001259114 RefSeq (Proteins) • NP_477257 NP_001246042 NP_001246043 DDBJ / EMBL / GenBank • AA697525 AAC99418 AAF45017 AAF53536 AAL28234 AE003416 AF102237 AFH03716 AFH03717 AI062770 AI062846 AI106583 AI107713 AI108757 AI113764 AI134724 AI134980 AI239042 AI257312 AY060686 Entrez Gene - A searchable database of RefSeq genes. • 34979 UniProtKB/Swiss-Prot • Q9V3D4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Glycoside hydrolase, family 18, catalytic domain (IPR001223) Chitinase II (IPR011583) Imaginal disc growth factor (IPR015520) Glycoside hydrolase, catalytic domain (IPR013781) Glycoside hydrolase, superfamily (IPR017853) PDB - Protein Data Bank. An information portal to biological macromolecular structures • 1JND 1JNE BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • CG4475 GH12581
Linkouts
	BioGRID - A database of protein and genetic interactions • 60988 DroID - A comprehensive database of gene and protein interactions. • FBgn0020415 DRSC - Results from RNAi screens. • FBgn0020415 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020415 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG4475-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0020415 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34979 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34979 modMine - Data generated by the modENCODE project. • FBgn0020415
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	BG:DS02780.4 (Ashburner et al., 1999.10.12, Ashburner et al., 1999) CG4475 (Karlsson et al., 2004, Vierstraete et al., 2003, Zhu et al., 2004, Mosallanejad et al., 2010, Cammarato et al., 2011) DmIDGF2 (Zhu et al., 2008) IDGF (Britton et al., 1999, Edgar, 2006) IDGF2 (Monserrate et al., 2003, Monserrate et al., 2003, Kawamura, 1998.10.28, Hipfner and Cohen, 1999, Kucerova and Zurovec, 2007) IDGF-2 (Varela et al., 2002) idgf2 (Reese et al., 2000, Reese et al., 2000, Moorman et al., 2006) Idgf2 (Jordan et al., 2005, Blanco et al., 2010, Zhu et al., 2004, Chen et al., 2011, Gilchrist et al., 2008, Ayroles et al., 2009, Bartkuhn et al., 2009, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	Imaginal disc growth factor 2 (Kawamura et al., 1997, Gonsalves et al., 2011, Cammarato et al., 2011)
Secondary FlyBase IDs
	FBgn0027923
References ( 56 )
Generate a list of	All references relating to this gene ( 56 )
List References by type	Research paper  ( 26 ) Supplementary material  ( 8 ) Review  ( 2 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 7 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 1 ) Stock list  ( 1 ) Curated genome annotation  ( 3 ) Website  ( 1 )
Recent research papers ( 2 )
	Chen et al., 2011, J. Biol. Chem. 286(11): 9020--9030 E2 Ligase dRad6 Regulates DMP53 Turnover in Drosophila. [FBrf0213391] Gonsalves et al., 2011, BMC Genomics 12: 475 Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. [FBrf0216487] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...