Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Antibody raised to C-terminal peptide -ASSAKKKKKTRRIEK
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\GluRIIB using the Feature Mapper tool.
GluRIIB transcripts are expressed exclusively in muscle. They are first detected in late stage 12 and reach maximal levels in stage 14 of embryogenesis. They are still present in the somatic musculature in stages 15-17 but at lower levels. GluRIIB transcripts are also detected at low levels in gut-associated muscle.
GBrowse - Visual display of RNA-Seq signalsView Dmel\GluRIIB in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: GluRIIB CG7234
GluRIIC is required for synaptic localisation of GluRIIA and GluRIIB proteins. Either GluRIIA or GluRIIB, but not both, is required for synaptic localisation of GluRIIC protein. GluRIIA and GluRIIB proteins compete with each other for access to GluRIIC protein and subsequent localisation to the synapse.
Glutamate receptor channels in Drosophila embryos and larvae have been studied using the patch-clamp technique.