• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dvir\Jhe

General Information
Symbol	Dvir\Jhe	Species	D. virilis
Name	Juvenile hormone esterase	Annotation symbol
Feature type	gene	FlyBase ID	FBgn0020458
Gene Model Status	Unannotated	Stock availability	None publicly available
Also Known As	JH
Genomic Location
Chromosome (arm)		Recombination map
Cytogenetic map		Sequence location
Summary Information
Automatically generated summary See sections below for more information	The gene Juvenile hormone esterase is referred to in FlyBase by the symbol Dvir\Jhe (FBgn0020458). It is a gene from Drosophila virilis. Its molecular function is unknown. The biological processes in which it is involved are not known. No alleles are reported. It has no annotated transcripts. Gene has not been localized to the genome sequence.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Mapped Features
Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Dvir\Jhe Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Dvir\Jhe Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Dvir\Jhe allele Gene References
External Data
Linkouts
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Ortholog(s) in Drosophila melanogaster (None identified)
No D. melanogaster orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 0 )
cDNA Clones ( 0 )
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	Heat stress results in delay of oviposition and a decrease in juvenile hormone hydrolysis and fertility, which lasted several days after heat treatment. (Gruntenko et al., 1996) The course of changes in the activities of enzymes degrading juvenile hormone (JH) during development is studied and the possible role of the proteins in the regulation of JH titre in critical developmental periods and in reproduction are investigated. (Khlebodarova et al., 1996) Flies respond to stressing effects by a decrease in the level of Juvenile hormone (JH) hydrolysis, delay in oviposition and a decrease in fertility for a few days. The decrease in level of JH hydrolysis may be responsible for the response of the reproductive system to stress. (Rauschenbach et al., 1996) Two forms of Dvir\Jhe are identified by ion exchange chromatography, one sensitive and one insensitive to DFP (diisopropylphosphofluridate). Females respond to heat stress by a decrease in activity of Dvir\Jhe. This decrease is effected through a decrease in protein. Dvir\Jhe metabolism in males does not change under heat stress. (Rauschenbach et al., 1995) The activity of Dvir\Jhe in adult D.virilis females decreases in response to heat stress. (Raushenbakh et al., 1995) Inhibition of Dvir\Jhe activity using paraoxon inhibits D.virilis metamorphosis. (Rauschenbach et al., 1991)
External Crossreferences & Linkouts
Sequence Crossreferences
Other Crossreferences
Linkouts
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Dvir\Jhe   JH (Gruntenko et al., 1996, Rauschenbach et al., 1991) Jhe (Crone et al., 2007)
Name Synonym	JE esterase (Gruntenko et al., 2005) JH esterase (Rauschenbach et al., 1991, Raushenbakh et al., 1995) Juvenile hormone esterase (Gruntenko et al., 1996)
Secondary FlyBase IDs
References ( 13 )
Research paper	Crone et al., 2007, Insect Biochem. Mol. Biol. 37(6): 540--549 Only one esterase of Drosophila melanogaster is likely to degrade juvenile hormone in vivo. [FBrf0200538] Gruntenko et al., 2005, J. Insect Physiol. 51(9): 959--968 Effects of dopamine on juvenile hormone metabolism and fitness in Drosophila virilis. [FBrf0190995] Khlebadarova et al., 1998, Genetika, Moscow 34(5): 625--628 [Genes, controlling the response of the juvenile hormone degradation system to stress in the Drosophila virilis imago, linked to chromosome 6.] [FBrf0104759] Grenback et al., 1997, Genetika, Moscow 33(7): 920--923 [Genetic control of the activity of DFP-sensitive juvenile hormone esterase in D. virilis.] [FBrf0099238] Grenback et al., 1997, Russ. J. Genet. 33(7): 776--779 Genetic control of the activity of DFP-sensitive juvenile hormone esterase in D. virilis. [FBrf0105084] Gruntenko et al., 1996, Genetika, Moscow 32(9): 1191--1198 [The role of juvenile hormone metabolism in adaptation of the Drosophila population to stressful environments.] [FBrf0091384] Khlebodarova et al., 1996, Insect Biochem. Mol. Biol. 26(8-9): 829--835 A comparative analysis of juvenile hormone metabolyzing enzymes in two species of Drosophila during development. [FBrf0091392] Khlebodarova et al., 1996, Ontogenez 27(2): 126--130 [Enzymes of the juvenile hormone metabolism in ontogenesis of Drosophila virilis.] [FBrf0088288] Rauschenbach et al., 1996, J. Insect Physiol. 42(8): 735--742 The role of degradation system of the juvenile hormone in the reproduction of Drosophila under stress. [FBrf0090753] Rauschenbach et al., 1995, J. Insect Physiol. 41(2): 179--189 Metabolism of the juvenile hormone in Drosophila adults under normal conditions and heat stress: Genetical and biochemical aspects. [FBrf0080343] Raushenbakh et al., 1995, Genetika, Moscow 31(2): 193--200 [Genetic analysis of differences in metabolism of juvenile hormone in lines of Drosophila virilis that are resistant and sensitive to heat shock.] [FBrf0080344] Rauschenbach et al., 1991, Ontogenez 22(3): 274--281 The role of JH-esterase in Diptera metamorphosis. [FBrf0074255] Rauschenbach et al., 1991, J. Insect Physiol. 37(7): 541--548 Role of juvenile hormone esterase in Diptera Drosophila virilis metamorphosis. [FBrf0054477]