dAbi, Abelson interactor, Ablphilin
Gene model reviewed during 5.48
1.7 (longest cDNA)
473 (aa); 52 (kD observed)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Abi using the Feature Mapper tool.
Abi is expressed in the brain and ventral nerve cord of the embryonic CNS, specifically in the commissures and longitudinal connectives. There is also some staining along the midline. In third instar larvae expression is observed in several regions of the brain including the neuropil, in axon fascicles of the ventral nerve cord, in photoreceptor cells in the eye disc, and in photoreceptor axons projecting through the optic stalk into the optic lobe.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Abi in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Abi CG9749
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation.