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Gene Dmel\Abi

General Information
Symbol	Dmel\Abi	Species	D. melanogaster
Name	Abelson interacting protein	Annotation symbol	CG9749
Feature type	protein_coding_gene	FlyBase ID	FBgn0020510
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	dAbi, Ablphilin
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	88A9-88A9	Sequence location	3R:9,944,984..9,948,142 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Abelson interacting protein is referred to in FlyBase by the symbol Dmel\Abi (CG9749, FBgn0020510). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence for 14 unique biological process terms, many of which group under: cellular component organization or biogenesis; cellular process; system development; biological regulation; organelle organization; cell projection assembly; actin filament-based process; sensory organ development; cell adhesion; multicellular organismal development; central nervous system neuron development; localization; regulation of developmental process; muscle cell differentiation; regulation of protein metabolic process. 18 alleles are reported. The phenotypes of these alleles are annotated with: dorsocentral bristle; chaeta; longitudinal connective; scutellar bristle; sensory mother cell. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Abl-interactor, homeo-domain homologous domain; Neutrophil cytosol factor 2 p67phox; Src homology-3 domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632196_at partially aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Abi: 13 out of 14 probes fall into this exonic region. Gene sequence location is 3R:9944984..9948142.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Georgiou and Baum, 2010, J. Cell Sci. 123(7): 1089--1098
FB2012_01	References Stephan et al., 2011, Mol. Biol. Cell 22(21): 4079--4092 Gautier et al., 2011, J. Cell Sci. 124(20): 3414--3427 D'Ambrosio and Vale, 2010, J. Cell Biol. 191(3): 471--478 Controlled Vocabulary Terms cell morphogenesis Sequence features HFA14099 BKN28071
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 88A9-88A9   Limits computationally determined from genome sequence between P{PZ}flfl01949 and P{lacW}trxj14A6&P{PZ}trx00347
Experimentally Determined Cytological Location
Cytogenetic map Notes References 88A-88B   (determined by in situ hybridisation)   (Gangadharan and Tear, 1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Abi for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Abi-RA FBtr0082910  NM_057915   2379   473 Abi-RB FBtr0112896  NM_001104315   2373   473 Abi-RC FBtr0307076     2291   472 Abi-RD FBtr0307077     2391   477
Additional Transcript Data & Comments
Reported size (kB)	1.7 (longest cDNA) (Juang and Hoffmann, 1999)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Abi-PA   FBpp0082371   51.9   473   6.93     NP_477263   AAF55021 Abi-PB   FBpp0111809   51.9   473   6.93     NP_001097785   ABW08669 Abi-PC   FBpp0297919   51.9   472   6.93       Abi-PD   FBpp0297920   52.4   477   7.09
Additional Polypeptide Data & Comments
Reported size (kDa)	473 (aa); 52 (kD observed) (Juang and Hoffmann, 1999)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Neutrophil cytosol factor 2 p67phox (IPR000108) Src homology-3 domain (IPR001452) Abl-interactor, homeo-domain homologous domain (IPR012849)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA949993   AA951542   AE014297 AAF55021   AE014297 ABW08669   AC007441   AC007904   AF151115 AAD38382   AI456605   AI456858   AI457032   AI516875   AI516885   AI519260   AI531987   AI534023   AI534026   AI541715   AW943364   AY051877 AAK93301   BF506031   BG635570   BG636879   BI161716   BI161717   BI165171   BI212807   BI228726   BI228860   BI228874   BI236593   BI357029   BI361342   BI366630   BI368086   BI368437   BI372841   BI374470   BI483470   BI483788   BI485711   BI485937   BI486535   BI486663   BI577944   BI579310   BI580622   BI632194   BI638387   CK660561   CO155030   CO273172   CO279512   CO293212   CO296753   CO336187   EC075192   EC076432   EC083682   EC220126   EC235173   EC265053   EC267450   EV593215   GH755714   GH756151   GH770749   GH772152   GH774565   GH783527   GH786202   GH788109   GH789638   GH791756   GH795878   GH801610   GH802158   GH819328   GH821615   GH826623   GH835376   GH835482   GH863564   GH868881   GH872177   GH875092   GH881030   GH890305   GH895607   GH895895   GH896949   GH898094   GH899637   GH901315   GH905008   GH910311   GH913949   GH914623   GH923722   GH923964   GH926393   GH934196   GH935461
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9Y0S9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0020510    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0020510 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0020510 expression level Developmental Stage   Expression Level embryo 00-02hr    4386 embryo 02-04hr    4249 embryo 04-06hr    4349 embryo 06-08hr    6106 embryo 08-10hr    5648 embryo 10-12hr    4949 embryo 12-14hr    4333 embryo 14-16hr    3491 embryo 16-18hr    2816 embryo 18-20hr    2481 embryo 20-22hr    1623 embryo 22-24hr    1797 larva L1    1562 larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1697 larva L3 puffstage 7-9    2131 white prepupae new    2474 white prepupae 12hr    2619 white prepupae 24hr    3034 pupae 2d postWPP    2595 pupae 3d postWPP    1672 pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day    1515 adult male 30day    1413 adult female 01day    1865 adult female 05day    2524 adult female 30day    2633 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4386) embryo 02-04hr  (4249) embryo 04-06hr  (4349) embryo 06-08hr  (6106) embryo 08-10hr  (5648) embryo 10-12hr  (4949) embryo 12-14hr  (4333) embryo 14-16hr  (3491) embryo 16-18hr  (2816) embryo 18-20hr  (2481) embryo 20-22hr  (1623) embryo 22-24hr  (1797) larva L1  (1562) larva L2  (1153) larva L3 12hr old  (1048) larva L3 puffstage 1-2  (1098) larva L3 puffstage 3-6  (1697) larva L3 puffstage 7-9  (2131) white prepupae new  (2474) white prepupae 12hr  (2619) white prepupae 24hr  (3034) pupae 2d postWPP  (2595) pupae 3d postWPP  (1672) pupae 4d postWPP  (1094) adult male 01day  (1264) adult male 05day  (1515) adult male 30day  (1413) adult female 01day  (1865) adult female 05day  (2524) adult female 30day  (2633) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4386) embryo 02-04hr  (4249) embryo 04-06hr  (4349) embryo 06-08hr  (6106) embryo 08-10hr  (5648) embryo 10-12hr  (4949) embryo 12-14hr  (4333) embryo 14-16hr  (3491) embryo 16-18hr  (2816) embryo 18-20hr  (2481) embryo 20-22hr  (1623) embryo 22-24hr  (1797) larva L1  (1562) larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6  (1697) larva L3 puffstage 7-9  (2131) white prepupae new  (2474) white prepupae 12hr  (2619) white prepupae 24hr  (3034) pupae 2d postWPP  (2595) pupae 3d postWPP  (1672) pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day  (1515) adult male 30day  1413 adult female 01day  (1865) adult female 05day  (2524) adult female 30day  (2633) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4386 embryo 02-04hr    4249 embryo 04-06hr    4349 embryo 06-08hr    6106 embryo 08-10hr    5648 embryo 10-12hr    4949 embryo 12-14hr    4333 embryo 14-16hr    3491 embryo 16-18hr    2816 embryo 18-20hr    2481 embryo 20-22hr    1623 embryo 22-24hr    1797 larva L1    1562 larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1697 larva L3 puffstage 7-9    2131 white prepupae new    2474 white prepupae 12hr    2619 white prepupae 24hr    3034 pupae 2d postWPP    2595 pupae 3d postWPP    1672 pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day    1515 adult male 30day    1413 adult female 01day    1865 adult female 05day    2524 adult female 30day    2633 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4386 embryo 02-04hr    4249 embryo 04-06hr    4349 embryo 06-08hr    6106 embryo 08-10hr    5648 embryo 10-12hr    4949 embryo 12-14hr    4333 embryo 14-16hr    3491 embryo 16-18hr    2816 embryo 18-20hr    2481 embryo 20-22hr    1623 embryo 22-24hr    1797 larva L1    1562 larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1697 larva L3 puffstage 7-9    2131 white prepupae new    2474 white prepupae 12hr    2619 white prepupae 24hr    3034 pupae 2d postWPP    2595 pupae 3d postWPP    1672 pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day    1515 adult male 30day    1413 adult female 01day    1865 adult female 05day    2524 adult female 30day    2633 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0020510 expression level Developmental Stage   Expression Level embryo 00-02hr    4386 embryo 02-04hr    4249 embryo 04-06hr    4349 embryo 06-08hr    6106 embryo 08-10hr    5648 embryo 10-12hr    4949 embryo 12-14hr    4333 embryo 14-16hr    3491 embryo 16-18hr    2816 embryo 18-20hr    2481 embryo 20-22hr    1623 embryo 22-24hr    1797 larva L1    1562 larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1697 larva L3 puffstage 7-9    2131 white prepupae new    2474 white prepupae 12hr    2619 white prepupae 24hr    3034 pupae 2d postWPP    2595 pupae 3d postWPP    1672 pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day    1515 adult male 30day    1413 adult female 01day    1865 adult female 05day    2524 adult female 30day    2633 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4386) embryo 02-04hr  (4249) embryo 04-06hr  (4349) embryo 06-08hr  (6106) embryo 08-10hr  (5648) embryo 10-12hr  (4949) embryo 12-14hr  (4333) embryo 14-16hr  (3491) embryo 16-18hr  (2816) embryo 18-20hr  (2481) embryo 20-22hr  (1623) embryo 22-24hr  (1797) larva L1  (1562) larva L2  (1153) larva L3 12hr old  (1048) larva L3 puffstage 1-2  (1098) larva L3 puffstage 3-6  (1697) larva L3 puffstage 7-9  (2131) white prepupae new  (2474) white prepupae 12hr  (2619) white prepupae 24hr  (3034) pupae 2d postWPP  (2595) pupae 3d postWPP  (1672) pupae 4d postWPP  (1094) adult male 01day  (1264) adult male 05day  (1515) adult male 30day  (1413) adult female 01day  (1865) adult female 05day  (2524) adult female 30day  (2633) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4386) embryo 02-04hr  (4249) embryo 04-06hr  (4349) embryo 06-08hr  (6106) embryo 08-10hr  (5648) embryo 10-12hr  (4949) embryo 12-14hr  (4333) embryo 14-16hr  (3491) embryo 16-18hr  (2816) embryo 18-20hr  (2481) embryo 20-22hr  1623 embryo 22-24hr  1797 larva L1  1562 larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6  1697 larva L3 puffstage 7-9  2131 white prepupae new  (2474) white prepupae 12hr  (2619) white prepupae 24hr  (3034) pupae 2d postWPP  (2595) pupae 3d postWPP  1672 pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day  1515 adult male 30day  1413 adult female 01day  1865 adult female 05day  (2524) adult female 30day  (2633) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4386 embryo 02-04hr    4249 embryo 04-06hr    4349 embryo 06-08hr    6106 embryo 08-10hr    5648 embryo 10-12hr    4949 embryo 12-14hr    4333 embryo 14-16hr    3491 embryo 16-18hr    2816 embryo 18-20hr    2481 embryo 20-22hr    1623 embryo 22-24hr    1797 larva L1    1562 larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1697 larva L3 puffstage 7-9    2131 white prepupae new    2474 white prepupae 12hr    2619 white prepupae 24hr    3034 pupae 2d postWPP    2595 pupae 3d postWPP    1672 pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day    1515 adult male 30day    1413 adult female 01day    1865 adult female 05day    2524 adult female 30day    2633 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4386 embryo 02-04hr    4249 embryo 04-06hr    4349 embryo 06-08hr    6106 embryo 08-10hr    5648 embryo 10-12hr    4949 embryo 12-14hr    4333 embryo 14-16hr    3491 embryo 16-18hr    2816 embryo 18-20hr    2481 embryo 20-22hr    1623 embryo 22-24hr    1797 larva L1    1562 larva L2    1153 larva L3 12hr old    1048 larva L3 puffstage 1-2    1098 larva L3 puffstage 3-6    1697 larva L3 puffstage 7-9    2131 white prepupae new    2474 white prepupae 12hr    2619 white prepupae 24hr    3034 pupae 2d postWPP    2595 pupae 3d postWPP    1672 pupae 4d postWPP    1094 adult male 01day    1264 adult male 05day    1515 adult male 30day    1413 adult female 01day    1865 adult female 05day    2524 adult female 30day    2633 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0020510    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0020510 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0020510 expression level Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0020510 expression level Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    356.475 Larval Midgut    296.4 Larval Hindgut    286.9 Larval Malpighian Tubules    225.8 Larval Fat Body    221.9 Larval Salivary Gland    306.4 Larval Trachea    255.4 Larval Carcass    288.125 Adult Head    152.9 Adult Eye    136.925 Adult Brain    262.1 Adult Thoracic-Abdominal Ganglion    219.4 Adult Crop    210.2 Adult Midgut    219.8 Adult Hindgut    212.1 Adult Malpighian Tubules    155.2 Adult Fat Body    158.3 Adult Salivary Gland    233.4 Adult Heart    147.025 Adult VirginFemale Spermatheca    149 Adult InseminatedFemale Spermatheca    156.4 Adult Ovary    307.4 Adult Testis    190.6 Adult Male Accessory Gland    231.1 Adult Carcass    144.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    152.9   NA  Eye    136.925   NA  Brain    262.1   356.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    219.4   NA  Crop    210.2   296.4  Midgut    219.8   286.9  Hindgut    212.1   225.8  Malpighian Tubules    155.2   221.9  Fat Body    158.3   306.4  Salivary Gland    233.4   NA  Heart    147.025   255.4  Trachea    NA   NA  VirginFemale Spermatheca    149   NA  InseminatedFemale Spermatheca    156.4   NA  Ovary    307.4   NA  Testis    190.6   NA  Male Accessory Gland    231.1   288.125  Carcass    144.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_30
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020510 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9749-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage | germline clone | maternal effect | recessive Abiunspecified lethal | pupal stage (with AbiKO) AbiP2 lethal | pupal stage (with AbiP2) AbiKO lethal | pupal stage (with Df(3R)JY19) AbiKO AbiP2 lethal | recessive AbiKO viable, with Scer\GAL4pnr-MD237 AbiGD14302 Other Phenotypes Allele cell shape defective AbidsRNA.cKa neuroanatomy defective | embryonic stage (with AbiKO) AbiP2 neuroanatomy defective | embryonic stage (with AbiP2) AbiKO neuroanatomy defective | embryonic stage | maternal effect, with Df(3R)JY19/AbiP1 AbiP2 neuroanatomy defective | embryonic stage | maternal effect (with Df(3R)JY19), with AbiP2 AbiP1 visible, with Scer\GAL4sca-537.4 AbidsRNA.Scer\UAS AbiScer\UAS.T:Myr1 Phenotype manifest in Allele chaeta, with Scer\GAL4sca-537.4 AbidsRNA.Scer\UAS chaeta & mesothoracic tergum | ectopic, with Scer\GAL4sca-537.4 AbiScer\UAS.T:Myr1 dorsocentral bristle, with Scer\GAL4sca-537.4 AbidsRNA.Scer\UAS filamentous actin | ectopic, with Scer\GAL4en-e16E AbiScer\UAS.T:Myr1 longitudinal connective (with AbiKO) AbiP2 longitudinal connective (with AbiP2) AbiKO longitudinal connective (with Df(3R)JY19) AbiKO longitudinal connective | maternal effect, with Df(3R)JY19/AbiP1 AbiP2 longitudinal connective | maternal effect (with Df(3R)JY19), with AbiP2 AbiP1 notopleural bristle | supernumerary, with Scer\GAL4sca-537.4 AbiScer\UAS.T:Myr1 presumptive embryonic/larval nervous system | maternal effect Abiunspecified scutellar bristle, with Scer\GAL4sca-537.4 AbidsRNA.Scer\UAS sensory mother cell, with Scer\GAL4sca-537.4 AbidsRNA.Scer\UAS sensory mother cell | supernumerary, with Scer\GAL4sca-537.4 AbiScer\UAS.T:Myr1
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of Abi Class Mutagen Stocks Known lesion AbiEY20423 P-element activity 1 -- AbiKO loss of function allele recombination 0 Yes AbiP1 hypomorphic allele - genetic evidence 0 -- AbiP2 loss of function allele 0 -- Abiunspecified 0 --
Alleles Carried on Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Abi Class Mutagen Stocks Known lesion AbiGD14302 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes AbiKK108071 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Abia.Act5C in vitro construct - regulatory fusion 0 Yes AbiAct5C.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes AbidsRNA.cKa in vitro construct - RNAi 0 Yes AbidsRNA.cRa in vitro construct - RNAi 0 Yes AbidsRNA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes AbiEndsOut.L in vitro construct 0 Yes AbiScer\UAS.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes AbiScer\UAS.T:Myr1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes AbiΔC.Scer\UAS.T:Myr1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes AbiΔN.Scer\UAS.T:Myr1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes AbiΔSH3.Act5C.T:Ivir\HA1 in vitro construct - deletion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel7359 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14302} NA P{KK108071} NA P{UAS-Abi.Myr} NA P{UAS-Abi.RNAi} NA P{UAS-Abi.ΔC.Myr} NA P{UAS-Abi.ΔN.Myr} NA P{UAS-GFP-Abi} NA characterization construct P{EndsOut-Abi.L} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}AbiP1 NA P{EP}AbiP2 NA P{EPgy2}AbiEY20423 NA
Gene Ontology: Function, Process & Cellular Component ( 18 unique terms )
Terms Based on Experimental Evidence ( 17 terms )
Molecular Function
CV term Evidence References
protein binding inferred from physical interaction with Abl (Juang and Hoffmann, 1999) inferred from physical interaction with Hem AND inferred from physical interaction with WASp (Bogdan and Klambt, 2003) inferred from physical interaction with Ptp61F (Huang et al., 2007)
Biological Process
CV term Evidence References
actin cytoskeleton organization inferred from mutant phenotype (Bogdan et al., 2005, Lin et al., 2009) cell adhesion inferred from mutant phenotype (Jani and Schock, 2007) cell morphogenesis inferred from mutant phenotype (D'Ambrosio and Vale, 2010) cell projection assembly inferred from mutant phenotype (Kunda et al., 2003) central nervous system neuron axonogenesis inferred from mutant phenotype (Lin et al., 2009) chaeta development inferred from mutant phenotype (Bogdan et al., 2005) cortical actin cytoskeleton organization inferred from mutant phenotype (Kunda et al., 2003) Golgi organization inferred from mutant phenotype (Kondylis et al., 2011) lamellipodium assembly inferred from mutant phenotype (Huang et al., 2007) muscle attachment inferred from mutant phenotype (Jani and Schock, 2007) neuromuscular junction development inferred from genetic interaction with Abl (Lin et al., 2009) phagocytosis, engulfment inferred from mutant phenotype (Stroschein-Stevenson et al., 2006) positive regulation of protein kinase activity inferred from direct assay (Juang and Hoffmann, 1999) regulation of cell shape inferred from mutant phenotype (Kunda et al., 2003)
Cellular Component
CV term Evidence References
lamellipodium membrane inferred from direct assay (Huang et al., 2007) perinuclear region of cytoplasm inferred from direct assay (Huang et al., 2007)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
signal transducer activity inferred from sequence or structural similarity with EMBL:U17698 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Abi allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 66795 DroID - A comprehensive database of gene and protein interactions. • FBgn0020510 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41718
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18788 Dere\GG21491 Dgri\GH19698 Dmoj\GI24554 Dper\GL23309 Dpse\GA22007 Dsec\GM25884 Dsim\GD20455 Dvir\GJ22620 Dwil\GK10907 Dyak\GE10059
Curated drosophilid orthologs	Dpse\GA22007
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL014130-PA Aedes aegypti (mosquito) AGAP001046-PA Anopheles gambiae (mosquito) XP_397451.3 Apis mellifera (honey bee) XP_001946649.1 Acyrthosiphon pisum (pea aphid) 224182 Branchiostoma floridae (lancelet) XP_001895147.1 Brugia malayi (roundworm nematode) BGIBMGA012500-PA Bombyx mori (silk worm) ENSBTAP00000014635 Bos taurus (bovine) CN22759 Caenorhabditis brenneri (small nematode) CBP08148 Caenorhabditis briggsae (nematode) CE29545 Caenorhabditis elegans (worm) ENSCAFP00000018916 Canis familiaris (dog) ENSCINP00000023520 Ciona intestinalis (sea squirt) JA06209 Caenorhabditis japonica (nematode) cn02512 Cryptococcus neoformans (yeast-like fungus) CPIJ006389 Culex pipens (mosquito) ENSCPOP00000012991 Cavia porcellus (guinea pig) RP02371 Caenorhabditis remanei (nematode) ENSCSAVP00000002028 Ciona savignyi (sedentary tunicate) 225412 Capitella spl (polychaete worm) DDB0231426 Dictyostelium discoideum (amoeba) 308744 Daphnia pulex (daphnia) ENSDARP00000075457 Danio rerio (zebra fish) ENSECAP00000013440 Equus caballus (horse) ENSGACP00000010510 Gymnopilus aculeatus (mushroom) ENSGALP00000014166 Gallus gallus (chicken) ENSP00000295851 Homo sapiens (human) 107808 Lottia gigantea (owl limpet) ENSMODP00000020308 Monodelphis domestica (gray opossum) ENSMMUP00000000419 Macaca mulatta (rhesus monkey) ENSMUSP00000084679 Mus musculus (house mouse) XP_001600830.1 Nasonia vitripennis (wasp) ENSOANP00000009602 Ornithorynchus anatinus (platypus) ENSORLP00000000002 Oryzias latipes (japanese killifish) PHUM001470-PA Pediculus humanus (human body louse) PP06864 Pristionchus pacificus (nematode) ENSPPYP00000014633 Pongo pygmaeus (orangutan) ENSPTRP00000021934 Pan troglodytes (chimpanzee) ENSRNOP00000025215 Rattus norvegicus (norway rat) Smp_085740 Schistosoma mansoni (trematode parasite) XP_001193694.1 Strongylocentrotus purpuratus (purple sea urchin) 53937 Trichoplax adhaerens (metazoa) XP_973140.2 Tribolium castaneum (red flour beetle) ENSTNIP00000008666 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000012425 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000009002 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB10445 NV19099 NV17683 LH17230 ISCW002934 FBgn0227941 FBgn0212918 FBgn0209724 FBgn0191926 FBgn0180740 JGI_V11_308744 FBgn0081992 FBgn0160899 FBgn0147276 FBgn0127162 FBgn0113670 FBgn0095805 CPIJ018548 CPIJ006389 BGIBMGA012500 ACYPI006331 GB16071 AGAP001046 AAEL014130 PB21102 PHUM354390 GLEAN_00412
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	23107 y1 w67c23; P{EPgy2}AbiEY20423
VDRC	v100714 P{KK108071}VIE-260B v36142 w1118; P{GD14302}v36142/TM3
Genomic Clones ( 2 )
	BACR01H04 BACR10E03 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 94 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD37010
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08382 GH27462 GH27474 LD28582 LD32090 LD36681 LD37245 LD38782 LP19221 RE05002 RE18046 RE26358 RE26514 RE26531 RE32665 RE43368 RE45519 RE52209 RE53996 RE54407 RE60026 RE62068 RE66372 RE66733 RE69046 RE69301 RE69977 RE70118 RE71721 RE73324 RE74838 SD03315 SD06474 SD06485 SD06754 SD13022 SD14693 SD20663 SD25837
Other clones	21376 64859 73075 104400 524359 557084 CK01.127C.F1 Dmel_neb_010030_0644_3575 EK109908 EK134920 EK202151 EK215105 EN05234 EN12021 RE01144 RP003019079 RP003026214 RP003043089 RP003061345 RP003095640 RP003141825 RP003168811 RP003176338 RP003211824 RP003213625 RP003229536 RP003231105 RP003239802 RP003243584 RP003244820 RP003288214 RP003309513 RP003324467 RP003347243 RP003347645 RP003349687 RP003380048 RP003423472 RP003430202 RP003441948 RP003446234 RP003460309 RP003472758 RP003509574 RP003509661 RP003524201 RP003572025 RP003632968 RP003645712 RP003649259 RP003652484 RP003655823 RP003676667 RP003678673
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0020510 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41718
Antibody Information
	polyclonal (Gautier et al., 2011, Stephan et al., 2011, Georgiou and Baum, 2010)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Abi CG9749 (Zheng, 1999.11)
Source for database merge of
Additional comments
Other Comments
	S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells. (Stroschein-Stevenson et al., 2006) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation. (Rogers et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057915 NM_001104315 RefSeq (Proteins) • NP_477263 NP_001097785 DDBJ / EMBL / GenBank • AAD38382 AAF55021 AAK93301 ABW08669 AC007441 AC007904 AF151115 AI456858 AW943364 AY051877 Entrez Gene - A searchable database of RefSeq genes. • 41718 UniProtKB/TrEMBL • Q9Y0S9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Neutrophil cytosol factor 2 p67phox (IPR000108) Src homology-3 domain (IPR001452) Abl-interactor, homeo-domain homologous domain (IPR012849)
Linkouts
	BioGRID - A database of protein and genetic interactions • 66795 DroID - A comprehensive database of gene and protein interactions. • FBgn0020510 DRSC - Results from RNAi screens. • FBgn0020510 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020510 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9749-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0020510 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 41718 InParanoid A subset of ortholog calls from InParanoid. • AAEL014130-PA Aedes aegypti (mosquito) AGAP001046-PA Anopheles gambiae (mosquito) XP_397451.3 Apis mellifera (honey bee) XP_001946649.1 Acyrthosiphon pisum (pea aphid) 224182 Branchiostoma floridae (lancelet) XP_001895147.1 Brugia malayi (roundworm nematode) BGIBMGA012500-PA Bombyx mori (silk worm) ENSBTAP00000014635 Bos taurus (bovine) CN22759 Caenorhabditis brenneri (small nematode) CBP08148 Caenorhabditis briggsae (nematode) CE29545 Caenorhabditis elegans (worm) ENSCAFP00000018916 Canis familiaris (dog) ENSCINP00000023520 Ciona intestinalis (sea squirt) JA06209 Caenorhabditis japonica (nematode) cn02512 Cryptococcus neoformans (yeast-like fungus) CPIJ006389 Culex pipens (mosquito) ENSCPOP00000012991 Cavia porcellus (guinea pig) RP02371 Caenorhabditis remanei (nematode) ENSCSAVP00000002028 Ciona savignyi (sedentary tunicate) 225412 Capitella spl (polychaete worm) DDB0231426 Dictyostelium discoideum (amoeba) 308744 Daphnia pulex (daphnia) ENSDARP00000075457 Danio rerio (zebra fish) ENSECAP00000013440 Equus caballus (horse) ENSGACP00000010510 Gymnopilus aculeatus (mushroom) ENSGALP00000014166 Gallus gallus (chicken) ENSP00000295851 Homo sapiens (human) 107808 Lottia gigantea (owl limpet) ENSMODP00000020308 Monodelphis domestica (gray opossum) ENSMMUP00000000419 Macaca mulatta (rhesus monkey) ENSMUSP00000084679 Mus musculus (house mouse) XP_001600830.1 Nasonia vitripennis (wasp) ENSOANP00000009602 Ornithorynchus anatinus (platypus) ENSORLP00000000002 Oryzias latipes (japanese killifish) PHUM001470-PA Pediculus humanus (human body louse) PP06864 Pristionchus pacificus (nematode) ENSPPYP00000014633 Pongo pygmaeus (orangutan) ENSPTRP00000021934 Pan troglodytes (chimpanzee) ENSRNOP00000025215 Rattus norvegicus (norway rat) Smp_085740 Schistosoma mansoni (trematode parasite) XP_001193694.1 Strongylocentrotus purpuratus (purple sea urchin) 53937 Trichoplax adhaerens (metazoa) XP_973140.2 Tribolium castaneum (red flour beetle) ENSTNIP00000008666 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000012425 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000009002 Xenopus tropicalis (frog) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /genebrief/abi.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 41718 modMine - Data generated by the modENCODE project. • FBgn0020510 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB10445 NV19099 NV17683 LH17230 ISCW002934 FBgn0227941 FBgn0212918 FBgn0209724 FBgn0191926 FBgn0180740 JGI_V11_308744 FBgn0081992 FBgn0160899 FBgn0147276 FBgn0127162 FBgn0113670 FBgn0095805 CPIJ018548 CPIJ006389 BGIBMGA012500 ACYPI006331 GB16071 AGAP001046 AAEL014130 PB21102 PHUM354390 GLEAN_00412
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	Abi (Rogers et al., 2003, Huang et al., 2007, Chen et al., 2007, Stroschein-Stevenson et al., 2006, Jani and Schock, 2007, Huang et al., 2007, Stephan et al., 2008, Bogdan et al., 2005, Kondylis et al., 2007, Qurashi et al., 2007, Hilger et al., 2009, Gohl et al., 2010, Georgiou and Baum, 2010, D'Ambrosio and Vale, 2010) abi (Lin et al., 2009, Fricke et al., 2009, Kondylis et al., 2011) Abi-1 (Tepass et al., 2002) Ablphilin (Gangadharan, 1999.9.16, Gangadharan and Tear, 1999) CG9749 (Ramet et al., 2002, Rogers et al., 2003, Keleman et al., 2009.8.5) dAbi (Wahlstrom et al., 2001, Juang and Hoffmann, 1999, Lin et al., 2004, Ismail et al., 2009, Wang et al., 2010)
Name Synonym	Abelson Interacting Protein (Juang et al., 1997) Abelson interacting protein (Lin et al., 2009, Wang et al., 2010) Abelson interactor (Stephan et al., 2008, Gohl et al., 2010)
Secondary FlyBase IDs
References ( 55 )
Generate a list of	All references relating to this gene ( 55 )
List References by type	Research paper  ( 27 ) Supplementary material  ( 6 ) Review  ( 4 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 7 ) FlyBase analysis  ( 2 ) Curated genome annotation  ( 2 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 7 )
	Gautier et al., 2011, J. Cell Sci. 124(20): 3414--3427 Clathrin is required for Scar/Wave-mediated lamellipodium formation. [FBrf0216441] Kondylis et al., 2011, PLoS ONE 6(2): e17173 Identification of ER Proteins Involved in the Functional Organisation of the Early Secretory Pathway in Drosophila Cells by a Targeted RNAi Screen. [FBrf0213167] Stephan et al., 2011, Mol. Biol. Cell 22(21): 4079--4092 Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila. [FBrf0216499] D'Ambrosio and Vale, 2010, J. Cell Biol. 191(3): 471--478 A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. [FBrf0212211] Georgiou and Baum, 2010, J. Cell Sci. 123(7): 1089--1098 Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions. [FBrf0214990] Gohl et al., 2010, J. Biol. Chem. 285(51): 40171--40179 WAVE Forms Hetero- and Homo-oligomeric Complexes at Integrin Junctions in Drosophila Visualized by Bimolecular Fluorescence Complementation. [FBrf0212496] Wang et al., 2010, J. Cell Sci. 123(9): 1546--1556 Drosophila twinfilin is required for cell migration and synaptic endocytosis. [FBrf0210650] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...