Gene Dmel\Rack1

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General Information

Symbol

Dmel\Rack1

Species

D. melanogaster

Name

Receptor of activated protein kinase C 1

Annotation symbol

CG7111

Feature type

protein_coding_gene

FlyBase ID

FBgn0020618

Gene Model Status

Current

Stock availability

9 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

28D1-28D1

Sequence location

2L:7,825,626..7,827,252 [-]

Genomic Maps

Select View:

modENCODE GBrowse

Summary Information

Automatically generated summary

See sections below for more information

The gene Receptor of activated protein kinase C 1 is referred to in FlyBase by the symbol Dmel\Rack1 (CG7111, FBgn0020618). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: protein kinase C binding. There is experimental evidence that it is involved in the biological process: wing disc development; locomotory behavior; oviposition; cuticle development; oogenesis. 9 alleles are reported. The phenotypes of these alleles are annotated with: ring canal; trichogen cell; egg; cuticle; ovary; wing; female germline stem cell; egg chamber. It has one annotated transcript and one annotated polypeptide. Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626602_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Rack1. Gene sequence location is 2L:7825626..7827252.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2012_01

Sequence features

BKN29073

HFA03405

FB2011_10

References

Knowles-Barley, 2011.8.24, BrainTrap expression curation.

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

28D1-28D1

Limits computationally determined from genome sequence between P{EP}EP2178 and P{PZ}mts⁰²⁴⁹⁶

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

28D-28D

(Vani, 1997.4.5)

28D1-28D5

(determined by in situ hybridisation)

(Vani et al., 1997)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\Rack1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Rack1-RA

FBtr0079565

NM_057921

1115

318

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Rack1-PA

FBpp0079187

35.6

318

7.52

NP_477269

AAF52566

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

WD40/YVTN repeat-like-containing domain (IPR015943)

WD40-repeat-containing domain (IPR017986)

WD40 repeat (IPR001680)

WD40 repeat-like-containing domain (IPR011046)

WD40 repeat, conserved site (IPR019775)

WD40 repeat, subgroup (IPR019781)

WD40 repeat 2 (IPR019782)

G-protein beta WD-40 repeat (IPR020472)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

O18640

UniProtKB/TrEMBL

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0020618

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	max expr for FBgn0020618
	Very low expression bin max
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No expression (0 - 0)
	Extremely low expression (1 - 10)
	Very low expression (11 - 100)
	Low expression (101 - 400)
	Moderate expression (401 - 1400)
	Moderately high expression (1401 - 4000)
	High expression (4001 - 10000)
	Very high expression (10001 - 100000)
	Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0020618 expression level
Developmental Stage		Expression Level
embryo 00-02hr		140628
embryo 02-04hr		201419
embryo 04-06hr		171372
embryo 06-08hr		195753
embryo 08-10hr		196730
embryo 10-12hr		226263
embryo 12-14hr		137275
embryo 14-16hr		189295
embryo 16-18hr		162186
embryo 18-20hr		200747
embryo 20-22hr		180240
embryo 22-24hr		137779
larva L1		225990
larva L2		187527
larva L3 12hr old		166243
larva L3 puffstage 1-2		114352
larva L3 puffstage 3-6		117205
larva L3 puffstage 7-9		105472
white prepupae new		97956
white prepupae 12hr		85769
white prepupae 24hr		84588
pupae 2d postWPP		72063
pupae 3d postWPP		59430
pupae 4d postWPP		79378
adult male 01day		58778
adult male 05day		59029
adult male 30day		64909
adult female 01day		167142
adult female 05day		142329
adult female 30day		155601
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

Linear, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(140628)
embryo 02-04hr		(201419)
embryo 04-06hr		(171372)
embryo 06-08hr		(195753)
embryo 08-10hr		(196730)
embryo 10-12hr		(226263)
embryo 12-14hr		(137275)
embryo 14-16hr		(189295)
embryo 16-18hr		(162186)
embryo 18-20hr		(200747)
embryo 20-22hr		(180240)
embryo 22-24hr		(137779)
larva L1		(225990)
larva L2		(187527)
larva L3 12hr old		(166243)
larva L3 puffstage 1-2		(114352)
larva L3 puffstage 3-6		(117205)
larva L3 puffstage 7-9		(105472)
white prepupae new		(97956)
white prepupae 12hr		(85769)
white prepupae 24hr		(84588)
pupae 2d postWPP		(72063)
pupae 3d postWPP		(59430)
pupae 4d postWPP		(79378)
adult male 01day		(58778)
adult male 05day		(59029)
adult male 30day		(64909)
adult female 01day		(167142)
adult female 05day		(142329)
adult female 30day		(155601)
Expression Level Scale		None Extremely low Very low Low

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(140628)
embryo 02-04hr		(201419)
embryo 04-06hr		(171372)
embryo 06-08hr		(195753)
embryo 08-10hr		(196730)
embryo 10-12hr		(226263)
embryo 12-14hr		(137275)
embryo 14-16hr		(189295)
embryo 16-18hr		(162186)
embryo 18-20hr		(200747)
embryo 20-22hr		(180240)
embryo 22-24hr		(137779)
larva L1		(225990)
larva L2		(187527)
larva L3 12hr old		(166243)
larva L3 puffstage 1-2		(114352)
larva L3 puffstage 3-6		(117205)
larva L3 puffstage 7-9		(105472)
white prepupae new		(97956)
white prepupae 12hr		(85769)
white prepupae 24hr		(84588)
pupae 2d postWPP		(72063)
pupae 3d postWPP		(59430)
pupae 4d postWPP		(79378)
adult male 01day		(58778)
adult male 05day		(59029)
adult male 30day		(64909)
adult female 01day		(167142)
adult female 05day		(142329)
adult female 30day		(155601)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(140628)
embryo 02-04hr		(201419)
embryo 04-06hr		(171372)
embryo 06-08hr		(195753)
embryo 08-10hr		(196730)
embryo 10-12hr		(226263)
embryo 12-14hr		(137275)
embryo 14-16hr		(189295)
embryo 16-18hr		(162186)
embryo 18-20hr		(200747)
embryo 20-22hr		(180240)
embryo 22-24hr		(137779)
larva L1		(225990)
larva L2		(187527)
larva L3 12hr old		(166243)
larva L3 puffstage 1-2		(114352)
larva L3 puffstage 3-6		(117205)
larva L3 puffstage 7-9		(105472)
white prepupae new		(97956)
white prepupae 12hr		(85769)
white prepupae 24hr		(84588)
pupae 2d postWPP		(72063)
pupae 3d postWPP		(59430)
pupae 4d postWPP		(79378)
adult male 01day		(58778)
adult male 05day		(59029)
adult male 30day		(64909)
adult female 01day		(167142)
adult female 05day		(142329)
adult female 30day		(155601)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		140628
embryo 02-04hr		201419
embryo 04-06hr		171372
embryo 06-08hr		195753
embryo 08-10hr		196730
embryo 10-12hr		226263
embryo 12-14hr		137275
embryo 14-16hr		189295
embryo 16-18hr		162186
embryo 18-20hr		200747
embryo 20-22hr		180240
embryo 22-24hr		137779
larva L1		225990
larva L2		187527
larva L3 12hr old		166243
larva L3 puffstage 1-2		114352
larva L3 puffstage 3-6		117205
larva L3 puffstage 7-9		105472
white prepupae new		97956
white prepupae 12hr		85769
white prepupae 24hr		84588
pupae 2d postWPP		72063
pupae 3d postWPP		59430
pupae 4d postWPP		79378
adult male 01day		58778
adult male 05day		59029
adult male 30day		64909
adult female 01day		167142
adult female 05day		142329
adult female 30day		155601
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to maximum FBgn0020618 expression level
Developmental Stage		Expression Level
embryo 00-02hr		140628
embryo 02-04hr		201419
embryo 04-06hr		171372
embryo 06-08hr		195753
embryo 08-10hr		196730
embryo 10-12hr		226263
embryo 12-14hr		137275
embryo 14-16hr		189295
embryo 16-18hr		162186
embryo 18-20hr		200747
embryo 20-22hr		180240
embryo 22-24hr		137779
larva L1		225990
larva L2		187527
larva L3 12hr old		166243
larva L3 puffstage 1-2		114352
larva L3 puffstage 3-6		117205
larva L3 puffstage 7-9		105472
white prepupae new		97956
white prepupae 12hr		85769
white prepupae 24hr		84588
pupae 2d postWPP		72063
pupae 3d postWPP		59430
pupae 4d postWPP		79378
adult male 01day		58778
adult male 05day		59029
adult male 30day		64909
adult female 01day		167142
adult female 05day		142329
adult female 30day		155601
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(140628)
embryo 02-04hr		(201419)
embryo 04-06hr		(171372)
embryo 06-08hr		(195753)
embryo 08-10hr		(196730)
embryo 10-12hr		(226263)
embryo 12-14hr		(137275)
embryo 14-16hr		(189295)
embryo 16-18hr		(162186)
embryo 18-20hr		(200747)
embryo 20-22hr		(180240)
embryo 22-24hr		(137779)
larva L1		(225990)
larva L2		(187527)
larva L3 12hr old		(166243)
larva L3 puffstage 1-2		(114352)
larva L3 puffstage 3-6		(117205)
larva L3 puffstage 7-9		(105472)
white prepupae new		(97956)
white prepupae 12hr		(85769)
white prepupae 24hr		(84588)
pupae 2d postWPP		(72063)
pupae 3d postWPP		(59430)
pupae 4d postWPP		(79378)
adult male 01day		(58778)
adult male 05day		(59029)
adult male 30day		(64909)
adult female 01day		(167142)
adult female 05day		(142329)
adult female 30day		(155601)
Expression Level Scale		None Extremely low Very low Low

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(140628)
embryo 02-04hr		(201419)
embryo 04-06hr		(171372)
embryo 06-08hr		(195753)
embryo 08-10hr		(196730)
embryo 10-12hr		(226263)
embryo 12-14hr		(137275)
embryo 14-16hr		(189295)
embryo 16-18hr		(162186)
embryo 18-20hr		(200747)
embryo 20-22hr		(180240)
embryo 22-24hr		(137779)
larva L1		(225990)
larva L2		(187527)
larva L3 12hr old		(166243)
larva L3 puffstage 1-2		(114352)
larva L3 puffstage 3-6		(117205)
larva L3 puffstage 7-9		(105472)
white prepupae new		(97956)
white prepupae 12hr		(85769)
white prepupae 24hr		(84588)
pupae 2d postWPP		(72063)
pupae 3d postWPP		(59430)
pupae 4d postWPP		(79378)
adult male 01day		(58778)
adult male 05day		(59029)
adult male 30day		(64909)
adult female 01day		(167142)
adult female 05day		(142329)
adult female 30day		(155601)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(140628)
embryo 02-04hr		(201419)
embryo 04-06hr		(171372)
embryo 06-08hr		(195753)
embryo 08-10hr		(196730)
embryo 10-12hr		(226263)
embryo 12-14hr		(137275)
embryo 14-16hr		(189295)
embryo 16-18hr		(162186)
embryo 18-20hr		(200747)
embryo 20-22hr		(180240)
embryo 22-24hr		(137779)
larva L1		(225990)
larva L2		(187527)
larva L3 12hr old		(166243)
larva L3 puffstage 1-2		(114352)
larva L3 puffstage 3-6		(117205)
larva L3 puffstage 7-9		(105472)
white prepupae new		(97956)
white prepupae 12hr		(85769)
white prepupae 24hr		(84588)
pupae 2d postWPP		(72063)
pupae 3d postWPP		(59430)
pupae 4d postWPP		(79378)
adult male 01day		(58778)
adult male 05day		(59029)
adult male 30day		(64909)
adult female 01day		(167142)
adult female 05day		(142329)
adult female 30day		(155601)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		140628
embryo 02-04hr		201419
embryo 04-06hr		171372
embryo 06-08hr		195753
embryo 08-10hr		196730
embryo 10-12hr		226263
embryo 12-14hr		137275
embryo 14-16hr		189295
embryo 16-18hr		162186
embryo 18-20hr		200747
embryo 20-22hr		180240
embryo 22-24hr		137779
larva L1		225990
larva L2		187527
larva L3 12hr old		166243
larva L3 puffstage 1-2		114352
larva L3 puffstage 3-6		117205
larva L3 puffstage 7-9		105472
white prepupae new		97956
white prepupae 12hr		85769
white prepupae 24hr		84588
pupae 2d postWPP		72063
pupae 3d postWPP		59430
pupae 4d postWPP		79378
adult male 01day		58778
adult male 05day		59029
adult male 30day		64909
adult female 01day		167142
adult female 05day		142329
adult female 30day		155601
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

FlyAtlas Anatomical Expression Data for FBgn0020618

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	max expr for FBgn0020618
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0020618 expression level
Tissue		Expression Level
Larval Central Nervous System		2437.225
Larval Midgut		2909.3
Larval Hindgut		3551.9
Larval Malpighian Tubules		3490
Larval Fat Body		6119
Larval Salivary Gland		6489.5
Larval Trachea		5149.6
Larval Carcass		3978.675
Adult Head		3701.4
Adult Eye		4688.075
Adult Brain		2317.4
Adult Thoracic-Abdominal Ganglion		3048.9
Adult Crop		4200.4
Adult Midgut		3918.8
Adult Hindgut		3800.5
Adult Malpighian Tubules		3773.1
Adult Fat Body		4959.6
Adult Salivary Gland		8872.1
Adult Heart		5145.325
Adult VirginFemale Spermatheca		3679.1
Adult InseminatedFemale Spermatheca		3891.6
Adult Ovary		2748.2
Adult Testis		620
Adult Male Accessory Gland		7850.8
Adult Carcass		4211.3
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(2437.225)
Larval Midgut		(2909.3)
Larval Hindgut		(3551.9)
Larval Malpighian Tubules		(3490)
Larval Fat Body		(6119)
Larval Salivary Gland		(6489.5)
Larval Trachea		(5149.6)
Larval Carcass		(3978.675)
Adult Head		(3701.4)
Adult Eye		(4688.075)
Adult Brain		(2317.4)
Adult Thoracic-Abdominal Ganglion		(3048.9)
Adult Crop		(4200.4)
Adult Midgut		(3918.8)
Adult Hindgut		(3800.5)
Adult Malpighian Tubules		(3773.1)
Adult Fat Body		(4959.6)
Adult Salivary Gland		(8872.1)
Adult Heart		(5145.325)
Adult VirginFemale Spermatheca		(3679.1)
Adult InseminatedFemale Spermatheca		(3891.6)
Adult Ovary		(2748.2)
Adult Testis		(620)
Adult Male Accessory Gland		(7850.8)
Adult Carcass		(4211.3)
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		(2437.225)
Larval Midgut		(2909.3)
Larval Hindgut		(3551.9)
Larval Malpighian Tubules		(3490)
Larval Fat Body		(6119)
Larval Salivary Gland		(6489.5)
Larval Trachea		(5149.6)
Larval Carcass		(3978.675)
Adult Head		(3701.4)
Adult Eye		(4688.075)
Adult Brain		(2317.4)
Adult Thoracic-Abdominal Ganglion		(3048.9)
Adult Crop		(4200.4)
Adult Midgut		(3918.8)
Adult Hindgut		(3800.5)
Adult Malpighian Tubules		(3773.1)
Adult Fat Body		(4959.6)
Adult Salivary Gland		(8872.1)
Adult Heart		(5145.325)
Adult VirginFemale Spermatheca		(3679.1)
Adult InseminatedFemale Spermatheca		(3891.6)
Adult Ovary		(2748.2)
Adult Testis		620
Adult Male Accessory Gland		(7850.8)
Adult Carcass		(4211.3)
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		2437.225
Larval Midgut		2909.3
Larval Hindgut		3551.9
Larval Malpighian Tubules		3490
Larval Fat Body		6119
Larval Salivary Gland		6489.5
Larval Trachea		5149.6
Larval Carcass		3978.675
Adult Head		3701.4
Adult Eye		4688.075
Adult Brain		2317.4
Adult Thoracic-Abdominal Ganglion		3048.9
Adult Crop		4200.4
Adult Midgut		3918.8
Adult Hindgut		3800.5
Adult Malpighian Tubules		3773.1
Adult Fat Body		4959.6
Adult Salivary Gland		8872.1
Adult Heart		5145.325
Adult VirginFemale Spermatheca		3679.1
Adult InseminatedFemale Spermatheca		3891.6
Adult Ovary		2748.2
Adult Testis		620
Adult Male Accessory Gland		7850.8
Adult Carcass		4211.3
Expression Level Scale		None Low Moderate High Very high

log, scaled to maximum FBgn0020618 expression level
Tissue		Expression Level
Larval Central Nervous System		2437.225
Larval Midgut		2909.3
Larval Hindgut		3551.9
Larval Malpighian Tubules		3490
Larval Fat Body		6119
Larval Salivary Gland		6489.5
Larval Trachea		5149.6
Larval Carcass		3978.675
Adult Head		3701.4
Adult Eye		4688.075
Adult Brain		2317.4
Adult Thoracic-Abdominal Ganglion		3048.9
Adult Crop		4200.4
Adult Midgut		3918.8
Adult Hindgut		3800.5
Adult Malpighian Tubules		3773.1
Adult Fat Body		4959.6
Adult Salivary Gland		8872.1
Adult Heart		5145.325
Adult VirginFemale Spermatheca		3679.1
Adult InseminatedFemale Spermatheca		3891.6
Adult Ovary		2748.2
Adult Testis		620
Adult Male Accessory Gland		7850.8
Adult Carcass		4211.3
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(2437.225)
Larval Midgut		(2909.3)
Larval Hindgut		(3551.9)
Larval Malpighian Tubules		(3490)
Larval Fat Body		(6119)
Larval Salivary Gland		(6489.5)
Larval Trachea		(5149.6)
Larval Carcass		(3978.675)
Adult Head		(3701.4)
Adult Eye		(4688.075)
Adult Brain		(2317.4)
Adult Thoracic-Abdominal Ganglion		(3048.9)
Adult Crop		(4200.4)
Adult Midgut		(3918.8)
Adult Hindgut		(3800.5)
Adult Malpighian Tubules		(3773.1)
Adult Fat Body		(4959.6)
Adult Salivary Gland		(8872.1)
Adult Heart		(5145.325)
Adult VirginFemale Spermatheca		(3679.1)
Adult InseminatedFemale Spermatheca		(3891.6)
Adult Ovary		(2748.2)
Adult Testis		620
Adult Male Accessory Gland		(7850.8)
Adult Carcass		(4211.3)
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		(2437.225)
Larval Midgut		(2909.3)
Larval Hindgut		(3551.9)
Larval Malpighian Tubules		(3490)
Larval Fat Body		(6119)
Larval Salivary Gland		(6489.5)
Larval Trachea		(5149.6)
Larval Carcass		(3978.675)
Adult Head		(3701.4)
Adult Eye		(4688.075)
Adult Brain		(2317.4)
Adult Thoracic-Abdominal Ganglion		(3048.9)
Adult Crop		(4200.4)
Adult Midgut		(3918.8)
Adult Hindgut		(3800.5)
Adult Malpighian Tubules		(3773.1)
Adult Fat Body		(4959.6)
Adult Salivary Gland		(8872.1)
Adult Heart		(5145.325)
Adult VirginFemale Spermatheca		(3679.1)
Adult InseminatedFemale Spermatheca		(3891.6)
Adult Ovary		(2748.2)
Adult Testis		620
Adult Male Accessory Gland		(7850.8)
Adult Carcass		(4211.3)
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		2437.225
Larval Midgut		2909.3
Larval Hindgut		3551.9
Larval Malpighian Tubules		3490
Larval Fat Body		6119
Larval Salivary Gland		6489.5
Larval Trachea		5149.6
Larval Carcass		3978.675
Adult Head		3701.4
Adult Eye		4688.075
Adult Brain		2317.4
Adult Thoracic-Abdominal Ganglion		3048.9
Adult Crop		4200.4
Adult Midgut		3918.8
Adult Hindgut		3800.5
Adult Malpighian Tubules		3773.1
Adult Fat Body		4959.6
Adult Salivary Gland		8872.1
Adult Heart		5145.325
Adult VirginFemale Spermatheca		3679.1
Adult InseminatedFemale Spermatheca		3891.6
Adult Ovary		2748.2
Adult Testis		620
Adult Male Accessory Gland		7850.8
Adult Carcass		4211.3
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	3701.4
NA	Eye	4688.075
NA	Brain	2317.4
2437.225	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	3048.9
NA	Crop	4200.4
2909.3	Midgut	3918.8
3551.9	Hindgut	3800.5
3490	Malpighian Tubules	3773.1
6119	Fat Body	4959.6
6489.5	Salivary Gland	8872.1
NA	Heart	5145.325
5149.6	Trachea	NA
NA	VirginFemale Spermatheca	3679.1
NA	InseminatedFemale Spermatheca	3891.6
NA	Ovary	2748.2
NA	Testis	620
NA	Male Accessory Gland	7850.8
3978.675	Carcass	4211.3

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010)

mE2_34_mRNA_expression_cluster_22

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0020618

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG7111-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal | embryonic stage | germline clone

Rack1^1.8

lethal | larval stage (with Rack1^EE)

Rack1^EY00128

lethal | larval stage (with Rack1^EY00128)

Rack1^EE

lethal | larval stage | recessive

viable, with Scer\GAL4^pnr-MD237

Rack1^GD12135

Sterility

Allele

sterile (with Df(2L)RACK1-mts)

sterile (with Rack1^1.8)

sterile (with Rack1^EE)

sterile (with Rack1^EY00128)

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

Rack1^GD12135

Phenotype manifest in

Allele

cuticle (with Df(2L)RACK1-mts)

cuticle (with Rack1^1.8)

cuticle (with Rack1^EE)

Rack1^1.8

cuticle (with Rack1^EY00128)

Rack1^1.8

egg (with Rack1^EE)

Rack1^EY00128

egg (with Rack1^EY00128)

Rack1^EE

egg chamber (with Df(2L)RACK1-mts)

Rack1^1.8

female germline stem cell (with Df(2L)RACK1-mts)

Rack1^1.8

female germline stem cell (with Rack1^EE)

Rack1^EY00128

female germline stem cell (with Rack1^EY00128)

Rack1^EE

ovary (with Df(2L)RACK1-mts)

ovary (with Rack1^1.8)

ovary (with Rack1^EE)

ovary (with Rack1^EY00128)

ovary | germline clone

Rack1^1.8

ring canal (with Df(2L)RACK1-mts)

Rack1^1.8

trichogen cell, with Scer\GAL4^pnr-MD237

Rack1^GD12135

wing (with Df(2L)RACK1-mts)

wing (with Rack1^1.8)

wing (with Rack1^EE)

Rack1^1.8

wing (with Rack1^EY00128)

Rack1^1.8

Classical Alleles ( 6 )

For All Classical Alleles Show

Allele of Rack1	Class	Mutagen	Stocks	Known lesion
Rack1^EY00128	loss of function allele	P-element activity	2	Yes
Rack1^1.8	loss of function allele	ethyl methanesulfonate	1	Yes
Rack1^e04283		piggyBac transposase	1	--
Rack1^EE	hypomorphic allele - genetic evidence	ethyl methanesulfonate	1	Yes
Rack1^c04220		piggyBac transposase	0	--
Rack1^CPTI001998		piggyBac transposase	0	Yes

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Rack1	Mutagen	Stocks	Known lesion
Rack1^GD12135	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
Rack1^HMS01173	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Rack1^KK109073	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel7032

(Ryder, 2004.4.26)

Df(2L)RACK1-mts

(Kadrmas et al., 2007)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD12135}

P{KK109073}

P{TRiP.HMS01173}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}Rack1^EY00128

miscellaneous insertions

PBac{681.P.FSVS-1}Rack1^CPTI001998

PBac{PB}Rack1^c04220

PBac{RB}Rack1^e04283

Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )

Terms Based on Experimental Evidence ( 9 terms )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

cuticle development