Gene Dmel\CG7179

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General Information

Symbol

Dmel\CG7179

Species

D. melanogaster

Name

Annotation symbol

CG7179

Feature type

protein_coding_gene

FlyBase ID

FBgn0020880

Gene Model Status

Current

Stock availability

2 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

28C3-28C3

Sequence location

2L:7,775,804..7,778,027 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG7179 (FBgn0020880). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: synaptic target recognition. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: CUB domain; Transcription activator LAG-3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult hindgut. Comments on Affy2 ProbeSet: ProbeSet 1623427_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG7179. Gene sequence location is 2L:7775804..7778027.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

28C3-28C3

Limits computationally determined from genome sequence between P{EP}EP2419^EP2419&P{EP}EP575 and P{PZ}l(2)rL220^rL220

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

28C2-28C2

(Wagner, 1997.8.8)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG7179 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG7179-RB

FBtr0301151

NM_164771

2224

696

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG7179-PB

FBpp0290374

78.1

696

6.00

NP_723315

AAF52554

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

CUB domain (IPR000859)

Transcription activator LAG-3 (IPR021587)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

adult hindgut precursor

(Fisher et al., 2012)

embryonic anal pad

(Fisher et al., 2012)

embryonic hindgut

(Fisher et al., 2012)

embryonic large intestine

(Fisher et al., 2012)

embryonic proventriculus

(Fisher et al., 2012)

embryonic salivary gland duct

(Fisher et al., 2012)

embryonic ventral epidermis

(Fisher et al., 2012)

embryonic/larval salivary gland common duct

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult hindgut.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		5.725
Larval Midgut		30.6
Larval Hindgut		132.8
Larval Malpighian Tubules		14.9
Larval Fat Body		10.6
Larval Salivary Gland		9.2
Larval Trachea		7.35
Larval Carcass		13.375
Adult Head		6.7
Adult Eye		3.675
Adult Brain		3.4
Adult Thoracic-Abdominal Ganglion		4.1
Adult Crop		8.6
Adult Midgut		10.2
Adult Hindgut		116.9
Adult Malpighian Tubules		15.2
Adult Fat Body		11.1
Adult Salivary Gland		56.2
Adult Heart		3.075
Adult VirginFemale Spermatheca		7.5
Adult InseminatedFemale Spermatheca		7.2
Adult Ovary		5.8
Adult Testis		3.4
Adult Male Accessory Gland		10.4
Adult Carcass		8.4
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	6.7
NA	Eye	3.675
NA	Brain	3.4
5.725	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	4.1
NA	Crop	8.6
30.6	Midgut	no informative data
132.8	Hindgut	116.9
no informative data	Malpighian Tubules	no informative data
no informative data	Fat Body	no informative data
9.2	Salivary Gland	no informative data
NA	Heart	3.075
7.35	Trachea	NA
NA	VirginFemale Spermatheca	7.5
NA	InseminatedFemale Spermatheca	7.2
NA	Ovary	5.8
NA	Testis	3.4
NA	Male Accessory Gland	no informative data
no informative data	Carcass	8.4

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		0
central nervous system, larvae L3		0
central nervous system, pupae P8		0
head, virgin 1-day female		0
head, virgin 4-day female		0
head, virgin 20-day female		0
head, mated 1-day female		0
head, mated 4-day female		0
head, mated 20-day female		0
head, mated 1-day male		0
head, mated 4-day male		0
head, mated 20-day male		0
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		0
digestive system, larvae L3 wandering		4
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		0
fat body, white prepupae		0
fat body, pupae P8		0
carcass, larvae L3 wandering		0
carcass, 1-day adult		0
carcass, 4-day adult		0
carcass, 20-day adult		0
ovary, virgin 4-day female		0
ovary, mated 4-day female		0
testis, mated 4-day male		0
accessory gland, mated 4-day male		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		1
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		0
embryo 12-14hr		1
embryo 14-16hr		8
embryo 16-18hr		19
embryo 18-20hr		22
embryo 20-22hr		15
embryo 22-24hr		17
larva L1		13
larva L2		15
larva L3 12hr old		5
larva L3 puffstage 1-2		1
larva L3 puffstage 3-6		2
larva L3 puffstage 7-9		3
white prepupae new		2
white prepupae 12hr		0
white prepupae 24hr		0
pupae 2d postWPP		0
pupae 3d postWPP		0
pupae 4d postWPP		0
adult male 01day		0
adult male 05day		0
adult male 30day		0
adult female 01day		0
adult female 05day		0
adult female 30day		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		0
cold shock, 4-day adult		0
heat shock, 4-day adult		0
Cadmium 50 mM 6 hrs, larvae L3		0
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		0
Cadmium 100 mM 48 hrs, 4-day adult		0
Copper 0.5 mM 12 hrs, larvae L3		0
Copper 15 mM 48 hrs, 4-day adult		0
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		0
Ethanol 2.5% 3 hrs, larvae L3		0
Ethanol 5% 3 hrs, larvae L3		0
Ethanol 10% 3 hrs, larvae L3		0
Caffeine 1.5 mg/ml 4 hrs, larvae L3		0
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		0
Caffeine 25 mg/ml 48 hrs, 4-day adult		0
Paraquat 5 mM 48 hrs, 4-day adult		0
Paraquat 10 mM 48 hrs, 4-day adult		0
Rotenone 2 μg 12 hrs, larvae L3		0
Rotenone 8 μg 12 hrs, larvae L3		0
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0020880

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG7179-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG7179

Stages(s) 7-8

Stages(s) 11-12

Stages(s) 13-16

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG7179^GD5240

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG7179	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG7179	Class	Mutagen	Stocks	Known lesion
CG7179^GD5240		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG7179^KK104440		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD5240}

P{KK104440}

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 1 term )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

synaptic target recognition

inferred from mutant phenotype

(Kurusu et al., 2008)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG7179 allele

Gene

References

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0020880

Orthologs

OrthoDB Orthologs (17) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6RXZK6

Dipteran inclusive ortholog search

EOG62562N

Insect inclusive ortholog search

EOG60VTKF

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Orthologs in Drosophila Species (EOG6RXZK6)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA25828

Drosophila persimilis

Dper\GL18852

Drosophila willistoni

Dwil\GK24641

Drosophila virilis

Dvir\GJ16282

Drosophila mojavensis

Dmoj\GI14508

Drosophila grimshawi

Dgri\GH13215

Orthologs in non-Drosophila Dipterans (EOG62562N)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL002217

Anopheles gambiae

Malaria mosquito

Agam\AGAP008441

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ003457

Orthologs in non-Dipteran Insects (EOG60VTKF)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG006173

Tribolium castaneum

Red flour beetle

Tcas\TC013670

Orthologs in non-Insect Arthropods (None identified)

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (None identified)

No non-Arthropod Metazoa orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA25828

Drosophila persimilis

Dper\GL18852

Drosophila willistoni

Dwil\GK24641

Drosophila virilis

Dvir\GJ16282

Drosophila mojavensis

Dmoj\GI14508

Drosophila grimshawi

Dgri\GH13215

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

VDRC

v100471

P{KK104440}VIE-260B

v13213

w¹¹¹⁸; P{GD5240}v13213

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 2 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

RE37904

Other clones

MIP06632

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0020880

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

34059

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_164771

RefSeq (Proteins)

•

NP_723315

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

34059

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

CUB domain (IPR000859)

Transcription activator LAG-3 (IPR021587)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0020880

DRSC - Results from RNAi screens.

•

FBgn0020880

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0020880

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG7179-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0020880

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

34059

modMine - Data generated by the modENCODE project.

•

FBgn0020880

Synonyms & Secondary IDs ( 5 )

Reported As

Symbol Synonym

anon-28Cg

CG7179

(Kurusu et al., 2008, Keleman et al., 2009.8.5)

CT22169

(Hynes and Zhao, 2000)

Opa

(Wagner, 1997.8.8)

tld-like

(Hynes and Zhao, 2000)

Name Synonym

Secondary FlyBase IDs

References ( 15 )

Research paper

Kurusu et al., 2008, Neuron 59(6): 972--985: A screen of cell-surface molecules identifies leucine-rich repeat proteins as key mediators of synaptic target selection. [FBrf0206073]
Friedman et al., 1991, Mol. Gen. Genet. 226: 81--87: The faint band/interband region 28C2 to 28C4-5(-) of the Drosophila melanogaster salivary gland polytene chromosomes is rich in transcripts. [FBrf0054722]

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Hynes and Zhao, 2000, J. Cell Biol. 150(2):: Table S6. EGF repeat and related adhesion proteins. [FBrf0132110]

Personal communication to FlyBase

Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Mount, 2001.8.14, Intron annotations.: Intron annotations. [FBrf0137489]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]

FlyBase analysis

FlyBase, 1992-, FlyBase curation.: FlyBase curation. [FBrf0105495]

DNA/RNA sequence record

Wagner, 1997.8.8, GenBank/EMBL/DDBJ: AF018078: Drosophila melanogaster Opa mRNA, complete cds. [FBrf0121867]

Website

Fisher et al., 2012, BDGP insitu homepage: BDGP insitu homepage [FBrf0219073]

Curated genome annotation

FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.]: [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705]

Thesis

Wagner, 1997, Ph.D. Thesis, Michigan State University, MI: ix + 158pp: Genetic characterization of the 27F;28D3-4 region of Drosophila melanogaster. [FBrf0100506]