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Gene Dmel\Scp1

General Information
Symbol	Dmel\Scp1	Species	D. melanogaster
Name	Sarcoplasmic calcium-binding protein 1	Annotation symbol	CG15848
Feature type	protein_coding_gene	FlyBase ID	FBgn0020908
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	2RHet	Recombination map	3-
Cytogenetic map	80A-80B	Sequence location	2RHet:1,707,564..1,743,021 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Sarcoplasmic calcium-binding protein 1 is referred to in FlyBase by the symbol Dmel\Scp1 (CG15848, FBgn0020908). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: calcium ion binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Calcium-binding EF-hand; EF-Hand 1, calcium-binding site; EF-hand-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: No FlyAtlas data available because no Affy2 ProbeSet aligns to an exon of Scp1. Comments on Affy2 ProbeSet: No relevant information because no Affy2 ProbeSet aligns to an exon of Scp1. Gene sequence location is 2RHet:1707564..1743021.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 80A-80B   Left limit from sequence databank entry AF014951 Right limit from sequence databank entry AF014951
Experimentally Determined Cytological Location
Cytogenetic map Notes References 80A-80B     (Drosophila Heterochromatin Genome Project, 2004) 80A-80B     (Kelly, 1997.7.18) 80-80   (determined by in situ hybridisation)   (Kelly et al., 1997)
Experimentally Determined Recombination Data
Location	3- (Kelly, 1997.7.18)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Scp1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all supported alternative splices within 5' UTR. Gene model reviewed during 5.47
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Scp1-RA FBtr0113713  NM_001015389   984   189 Scp1-RB FBtr0334933  NM_001276231   1198   189
Additional Transcript Data & Comments
Reported size (kB)	0.9 (longest cDNA) (Kelly et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Scp1-PA   FBpp0112436   21.6   189   4.50     NP_001015389   EAA46049 Scp1-PB   FBpp0306952   21.6   189   4.50     NP_001263160   ELP57405
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments	Based on comparison of amino acid composition, Scp2 protein may correspond to the previously identified CabP23 protein (FBrf0051230). (Kelly et al., 1997)
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • EF-Hand 1, calcium-binding site (IPR018247) EF-hand domain (IPR002048) EF-hand-like domain (IPR011992)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AABU01002760 EAA46049   AF014951   AI239116   AY118788   AY232072   BG632876   CO177220   CO177288   CO185964   CO264115   CO275860   CO276166   CO277987   CO285499   CO289916   CO294235   CO297311   CO298056   CO307241   CO307759   CO316273   CO320643   CO321570   CO322286   CO325248   CO328959   CO329627   CO331559   CO332801   CO333552   CO340688   CO341033   CO344882   CM000457 EAA46049   EC056917   EC059966   EC062574   EC064439   EC066097   EC066462   EC067254   EC067363   EC071720   EC074086   EC074859   EC090518   EC195683   EC207137   EC209683   EC212986   EC221461   EC222600   EC225386   EC226499   EC229187   EC239884   EC243641   EC246485   EC251192   EC252135   EC258075   CM000457 ELP57405   EV579420   EV583917   EV590654   EV591606   EV597130   EV598511
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MSI2 O16157
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
radioisotope in situ Stage Tissue/Position (including subcellular localization) Reference adult stage   mesothoracic extracoxal depressor muscle 66 | restricted   (Kelly et al., 1997)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female    50 head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female    35 head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male    32 head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult    900 carcass, 4-day adult    360 carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female  (50) head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female  (35) head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male  (32) head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult  (900) carcass, 4-day adult  (360) carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female    50 head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female    35 head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male    32 head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult  (900) carcass, 4-day adult  (360) carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female    50 head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female    35 head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male    32 head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult    900 carcass, 4-day adult    360 carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female    50 head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female    35 head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male    32 head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult    900 carcass, 4-day adult    360 carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female  (50) head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female  (35) head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male  32 head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult  (900) carcass, 4-day adult  (360) carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female    50 head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female    35 head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male    32 head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult  (900) carcass, 4-day adult  (360) carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    17 head, virgin 1-day female    50 head, virgin 4-day female    13 head, virgin 20-day female    1 head, mated 1-day female    35 head, mated 4-day female    4 head, mated 20-day female    1 head, mated 1-day male    32 head, mated 4-day male    8 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    2 digestive system, 4-day adult    1 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    12 carcass, larvae L3 wandering    1 carcass, 1-day adult    900 carcass, 4-day adult    360 carcass, 20-day adult    17 ovary, virgin 4-day female    1 ovary, mated 4-day female    1 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP    87 pupae 3d postWPP    812 pupae 4d postWPP    369 adult male 01day    609 adult male 05day    122 adult male 30day    11 adult female 01day    128 adult female 05day    53 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP  (87) pupae 3d postWPP  (812) pupae 4d postWPP  (369) adult male 01day  (609) adult male 05day  (122) adult male 30day    11 adult female 01day  (128) adult female 05day  (53) adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP    87 pupae 3d postWPP  (812) pupae 4d postWPP  (369) adult male 01day  (609) adult male 05day  (122) adult male 30day    11 adult female 01day  (128) adult female 05day    53 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP    87 pupae 3d postWPP    812 pupae 4d postWPP    369 adult male 01day    609 adult male 05day    122 adult male 30day    11 adult female 01day    128 adult female 05day    53 adult female 30day    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP    87 pupae 3d postWPP    812 pupae 4d postWPP    369 adult male 01day    609 adult male 05day    122 adult male 30day    11 adult female 01day    128 adult female 05day    53 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP  (87) pupae 3d postWPP  (812) pupae 4d postWPP  (369) adult male 01day  (609) adult male 05day  (122) adult male 30day    11 adult female 01day  (128) adult female 05day  (53) adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP    87 pupae 3d postWPP  (812) pupae 4d postWPP  (369) adult male 01day  (609) adult male 05day  122 adult male 30day    11 adult female 01day  128 adult female 05day    53 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    0 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    0 larva L2    0 larva L3 12hr old    0 larva L3 puffstage 1-2    0 larva L3 puffstage 3-6    0 larva L3 puffstage 7-9    1 white prepupae new    4 white prepupae 12hr    7 white prepupae 24hr    1 pupae 2d postWPP    87 pupae 3d postWPP    812 pupae 4d postWPP    369 adult male 01day    609 adult male 05day    122 adult male 30day    11 adult female 01day    128 adult female 05day    53 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    0 embryonic Kc167    2 embryonic S1    3 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    0 wing disc ML-DmD8    0 wing disc ML-DmD9    0 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    5 antennal disc ML-DmD20-c5    2 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    1 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult    89 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    53 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    170 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    207 Ethanol 2.5% 3 hrs, larvae L3    136 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    87 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    226 Paraquat 10 mM 48 hrs, 4-day adult    143 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult  (89) Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult  (53) Cadmium 100 mM 48 hrs, 4-day adult  (140) Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult  (170) Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult  (207) Ethanol 2.5% 3 hrs, larvae L3  (136) Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (87) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (226) Paraquat 10 mM 48 hrs, 4-day adult  (143) Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult    89 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    53 Cadmium 100 mM 48 hrs, 4-day adult  (140) Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult  (170) Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult  (207) Ethanol 2.5% 3 hrs, larvae L3  (136) Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    87 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (226) Paraquat 10 mM 48 hrs, 4-day adult  (143) Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult    89 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    53 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    170 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    207 Ethanol 2.5% 3 hrs, larvae L3    136 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    87 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    226 Paraquat 10 mM 48 hrs, 4-day adult    143 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult    89 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    53 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    170 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    207 Ethanol 2.5% 3 hrs, larvae L3    136 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    87 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    226 Paraquat 10 mM 48 hrs, 4-day adult    143 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult  (89) Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult  (53) Cadmium 100 mM 48 hrs, 4-day adult  (140) Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult  (170) Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult  (207) Ethanol 2.5% 3 hrs, larvae L3  (136) Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (87) Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (226) Paraquat 10 mM 48 hrs, 4-day adult  (143) Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult    89 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    53 Cadmium 100 mM 48 hrs, 4-day adult  140 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult  (170) Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult  (207) Ethanol 2.5% 3 hrs, larvae L3  136 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    87 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult  (226) Paraquat 10 mM 48 hrs, 4-day adult  143 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    16 cold shock, 4-day adult    12 heat shock, 4-day adult    89 Cadmium 50 mM 6 hrs, larvae L3    0 Cadmium 50 mM 12 hrs, larvae L3    0 Cadmium 50 mM 48 hrs, 4-day adult    53 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    0 Copper 15 mM 48 hrs, 4-day adult    170 Zinc 5 mM 12 hrs, larvae L3    0 Zinc 4.5 mM 48 hrs, 4-day adult    207 Ethanol 2.5% 3 hrs, larvae L3    136 Ethanol 5% 3 hrs, larvae L3    0 Ethanol 10% 3 hrs, larvae L3    0 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    87 Caffeine 25 mg/ml 48 hrs, 4-day adult    20 Paraquat 5 mM 48 hrs, 4-day adult    226 Paraquat 10 mM 48 hrs, 4-day adult    143 Rotenone 2 μg 12 hrs, larvae L3    0 Rotenone 8 μg 12 hrs, larvae L3    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
External Data & Images
Linkouts	BDGP expression data • GH15296 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020908 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15848-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Scp1 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Scp1 Class Mutagen Stocks Known lesion Scp1JF02573 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.JF02573} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
calcium ion binding inferred from sequence or structural similarity with UniProtKB:P02635 (FlyBase, 1992-) non-traceable author statement (Kelly, 1997.7.18)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
sarcoplasmic reticulum inferred from sequence or structural similarity with UniProtKB:P02635 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Scp1 - ATPsyn-Cf6 experimental knowledge based (Guruharsha et al., 2011) Scp1 - ATPsyn-b experimental knowledge based (Guruharsha et al., 2011) Scp1 - Acon experimental knowledge based (Guruharsha et al., 2011) Scp1 - Act79B experimental knowledge based (Guruharsha et al., 2011) Scp1 - Actn experimental knowledge based (Guruharsha et al., 2011) Scp1 - Adh experimental knowledge based (Guruharsha et al., 2011) Scp1 - Ald experimental knowledge based (Guruharsha et al., 2011) Scp1 - Argk experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG10581 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Scp1 - CG14207 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG16826 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG16885 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG31343 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG32473 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG32573 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - CG34205 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG3817 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - CG4769 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG5177 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG5500 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Scp1 - CG5506 experimental knowledge based (Guruharsha et al., 2011) Scp1 - CG5805 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - CG6330 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - Cyt-c-p experimental knowledge based (Guruharsha et al., 2011) Scp1 - Eb1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - Eno experimental knowledge based (Guruharsha et al., 2011) Scp1 - Fer1HCH experimental knowledge based (Guruharsha et al., 2011) Scp1 - Fer2LCH experimental knowledge based (Guruharsha et al., 2011) Scp1 - Gapdh2 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Gdh experimental knowledge based (Guruharsha et al., 2011) Scp1 - GlyP experimental knowledge based (Guruharsha et al., 2011) Scp1 - Gp210 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - Gpdh experimental knowledge based (Guruharsha et al., 2011) Scp1 - Iap2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - Lsp2 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Mdh2 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Mf experimental knowledge based (Guruharsha et al., 2011) Scp1 - Mhc experimental knowledge based (Guruharsha et al., 2011) Scp1 - Mlc1 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Mlc2 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Nc73EF experimental knowledge based (Guruharsha et al., 2011) Scp1 - Nplp2 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Obp56d experimental knowledge based (Guruharsha et al., 2011) Scp1 - Pdsw experimental knowledge based (Guruharsha et al., 2011) Scp1 - Pgk experimental knowledge based (Guruharsha et al., 2011) Scp1 - Pglym78 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Pp1-87B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - Prm experimental knowledge based (Guruharsha et al., 2011) Scp1 - Pxn anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - Rfabg experimental knowledge based (Guruharsha et al., 2011) Scp1 - SmD3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - Tm2 experimental knowledge based (Guruharsha et al., 2011) Scp1 - TpnC41C experimental knowledge based (Guruharsha et al., 2011) Scp1 - Tsf1 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Yp1 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Yp2 experimental knowledge based (Guruharsha et al., 2011) Scp1 - Yp3 experimental knowledge based (Guruharsha et al., 2011) Scp1 - isoQC anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Scp1 - kdn experimental knowledge based (Guruharsha et al., 2011) Scp1 - proPO-A1 experimental knowledge based (Guruharsha et al., 2011) Scp1 - up experimental knowledge based (Guruharsha et al., 2011) Scp1 - wupA experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Scp1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 78227 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0020908 DroID - A comprehensive database of gene and protein interactions. • FBgn0020908 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 3355102
Orthologs
OrthoDB Orthologs (25) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6BZNNZ Dipteran inclusive ortholog search EOG6001TD Insect inclusive ortholog search EOG6QZ6H7 Arthropod inclusive ortholog search EOG6N2Z55 Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6BZNNZ)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Scp1     Drosophila erecta   Dere\GG23100     Drosophila yakuba   Dyak\Scp1     Drosophila ananassae   Dana\GF14448     Drosophila persimilis   Dper\GL24797     Drosophila persimilis   Dper\GL25464     Drosophila willistoni   Dwil\GK21213     Drosophila mojavensis   Dmoj\GI18277     Drosophila grimshawi   Dgri\GH13373
Orthologs in non-Drosophila Dipterans (EOG6001TD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008844   Anopheles gambiae Malaria mosquito  Agam\AGAP007963   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ001560
Orthologs in non-Dipteran Insects (EOG6QZ6H7)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Scp1   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012203   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15013   Atta cephalotes Leafcutter ant  Acep\ACEP25561   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17308   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL13557   Linepithema humile Argentine ant  Lhum\LH16960   Pogonomyrmex barbatus Red harvester ant  Pbar\PB13475   Solenopsis invicta Red fire ant  Sinv\SINV23459   Bombyx mori Silkmoth  Bmor\BGIBMGA009050   Tribolium castaneum Red flour beetle  Tcas\GLEAN_05103
Orthologs in non-Insect Arthropods (EOG6N2Z55)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_308183   Ixodes scapularis Deer tick  Isca\ISCW014255
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
Bloomington	31957 y1 v1; P{TRiP.JF02573}attP2/TM3, Sb1
Genomic Clones ( 0 )
cDNA Clones ( 10 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	DPiM_GH15296 GH15296
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	Dmel_dig_006237_0648_0429 Dmel_dig_018520_0664_2876 Dmel_neb_013539_0320_2497 Dmel_neb_014518_0853_3327 Dmel_neb_014762_0347_0449 Dmel_neb_014872_0944_2162 EK185940 EP20128
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0020908 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3355102
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Scp1 BcDNA:GH15296 (FlyBase, 1996-) Source for merge of: Scp1 CG15848 (Bayraktaroglu, 2000.4.12)
Additional comments	Source for merge of Scp1 BcDNA:GH15296 was a shared cDNA (date:030206). (FlyBase, 1996-)
Other Comments
	cDNA identified using the DCABP-23 antibody. (Kelly et al., 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001015389 NM_001276231 RefSeq (Proteins) • NP_001015389 NP_001263160 DDBJ / EMBL / GenBank • AAB67804 AABU01002760 AAM50648 AF014951 AI239116 AY118788 BG632876 EAA46049 ELP57405 Entrez Gene - A searchable database of RefSeq genes. • 3355102 UniProtKB/TrEMBL • O16157 Q8MSI2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • EF-Hand 1, calcium-binding site (IPR018247) EF-hand domain (IPR002048) EF-hand-like domain (IPR011992) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH15296
Linkouts
	BioGRID - A database of protein and genetic interactions • 78227 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0020908 DroID - A comprehensive database of gene and protein interactions. • FBgn0020908 DRSC - Results from RNAi screens. • FBgn0020908 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0020908 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15848-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0020908 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3355102 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 3355102 modMine - Data generated by the modENCODE project. • FBgn0020908
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	BcDNA:GH15296   CG15848 (Drosophila Heterochromatin Genome Project, 2007, Perkins et al., 2009) Dcabp-A.1 (Kelly et al., 1997) SCP (Dimitri et al., 2003) SCP1 (Kelly, 1997.7.18) Scp1 (Sharma and Singh, 2009, Lin et al., 2012, Vujatovic et al., 2012)
Name Synonym	calcium biding protein (Zou et al., 2000) Drosophila Ca2+-binding protein A.1 (Kelly et al., 1997) Sarcoplasmic calcium-binding protein 1 (Pedersen et al., 2010)
Secondary FlyBase IDs
	FBan0015848 FBgn0039982 FBgn0063247
References ( 19 )
Research paper	Lin et al., 2012, PLoS ONE 7(6): e39758 HP1a Targets the Drosophila KDM4A Demethylase to a Subset of Heterochromatic Genes to Regulate H3K36me3 Levels. [FBrf0218736] Vujatovic et al., 2012, Nucleic Acids Res. 40(12): 5402--5414 Drosophila melanogaster linker histone dH1 is required for transposon silencing and to preserve genome integrity. [FBrf0218745] Pedersen et al., 2010, Heredity 104(2): 125--134 Proteomic characterization of a temperature-sensitive conditional lethal in Drosophila melanogaster. [FBrf0209741] Sharma and Singh, 2009, PLoS ONE 4(6): e5763 Detection of transgenerational spermatogenic inheritance of adult male acquired CNS gene expression characteristics using a Drosophila systems model. [FBrf0208166] Zou et al., 2000, Proc. Natl. Acad. Sci. U.S.A. 97(25): 13726--13731 Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. [FBrf0131436] Kelly et al., 1997, Insect Biochem. Mol. Biol. 27(8/9): 783--792 Identification of a gene family from Drosophila melanogaster encoding proteins with homology to invertebrate sarcoplasmic calcium-binding proteins (SCPS). [FBrf0099787]
Supplementary material	Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Review	Dimitri et al., 2003, Genetica 117(2-3): 209--215 Vital genes in the heterochromatin of chromosomes 2 and 3 of Drosophila melanogaster. [FBrf0158962]
Personal communication to FlyBase	Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Drosophila Heterochromatin Genome Project, 2007, Release 5.2 of the annotated Drosophila melanogaster heterochromatin. Release 5.2 of the annotated Drosophila melanogaster heterochromatin. [FBrf0199188] Drosophila Heterochromatin Genome Project, 2004, Release 3.2 of the annotated Drosophila melanogaster heterochromatin. Release 3.2 of the annotated Drosophila melanogaster heterochromatin. [FBrf0173307] Bayraktaroglu, 2000.4.12, Annotation identities: Category 10. Annotation identities: Category 10. [FBrf0126912] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
DNA/RNA sequence record	Kelly, 1997.7.18, GenBank/EMBL/DDBJ: AF014951 Drosophila melanogaster calcium-binding protein (SCP1) mRNA, partial cds. [FBrf0116844]
Curated genome annotation	Milshina, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126686]