Gene model reviewed during 5.42
Multiphase exon postulated: exon reading frame differs in alternative transcripts; overlap >20aa. (FBrf0194899).
Gene model reviewed during 5.43
Gene model reviewed during 5.51
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Xbp1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Xbp1 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In response to ER stress, the original processed transcript of this gene is subject to HAC1-type intron splice-site recognition and cleavage by the Ire1 gene product. A small intron of 23nt is enzymatically removed, creating a frameshift in the resulting transcript and production of an alternative protein isoform.
Changes in expression profiles associated with the unfolded protein response have been analyzed in S2 cells following treatment with dsRNA made from templates generated with primers directed against this gene.
Gene isolated in a screen of the second chromosome identifying mutants affecting disc morphology.