A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\eIF-3p40

General Information
SymbolDmel\eIF-3p40SpeciesD. melanogaster
NameEukaryotic initiation factor 3 p40 subunitAnnotation symbolCG9124
Feature typeprotein_coding_geneFlyBase IDFBgn0022023
Gene Model StatusCurrent Stock availability 9 publicly available
Also Known Asl(2)k09003
Genomic Location
Chromosome (arm)2LRecombination map
Cytogenetic map25C3-25C3Sequence location2L:5,051,193..5,053,209 [-]

Genomic Maps

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modENCODE GBrowse
detailed view
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Automatically generated summary

See sections below for more information
The gene Eukaryotic initiation factor 3 p40 subunit is referred to in FlyBase by the symbol Dmel\eIF-3p40 (CG9124, FBgn0022023). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Mov34/MPN/PAD-1. Summary of modENCODE Temporal Expression Profile: Very high expression at all stages of development. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1625078_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of eIF-3p40. Gene sequence location is 2L:5051193..5053209.

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Description
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What does this section not display?
This section does not currently display links that were removed or gene model changes.
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FB2011_10
Controlled Vocabulary Terms
FB2012_01
Sequence features
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
25C3-25C3  
Limits computationally determined from genome sequence between P{lacW}vkgk16721&P{lacW}Cg25Ck00405 and P{lacW}l(2)k11206k11206  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
25C1-25C2  
(determined by in situ hybridisation)  
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\eIF-3p40 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0301206 FBtr0079032 FBtr0079031 FBtr0079009 FBtr0079030 FBtr0079029 FBtr0079011 FBtr0079010 FBpp0290424 FBpp0078668 FBpp0089133 FBpp0078667 FBpp0078648 FBpp0078666 FBti0026111 FBti0033970 FBti0036443 FBti0006610 FBti0124576_1 FBti0124576_2 FBti0102409 FBti0115477 FBti0059011 FBti0113468 FBti0105317 FBti0029362 FBti0106227 FBti0105081
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0079030
  1611
  338
FBtr0079031
  1194
  338
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0078667  
38.4  
338  
6.01  
FBpp0089133  
38.4  
338  
6.01  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Mov34/MPN/PAD-1 (IPR000555)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view CG9121-RA eIF-3p40-RB CG14040-RA eIF-3p40-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0022023


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0022023
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Very high expression at all stages of development.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0022023 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 17931
embryo 02-04hr
 
 25163
embryo 04-06hr
 
 25918
embryo 06-08hr
 
 24681
embryo 08-10hr
 
 26816
embryo 10-12hr
 
 27869
embryo 12-14hr
 
 16855
embryo 14-16hr
 
 18625
embryo 16-18hr
 
 14654
embryo 18-20hr
 
 15346
embryo 20-22hr
 
 15188
embryo 22-24hr
 
 13854
larva L1
 
 25088
larva L2
 
 20511
larva L3 12hr old
 
 15686
larva L3 puffstage 1-2
 
 15228
larva L3 puffstage 3-6
 
 16380
larva L3 puffstage 7-9
 
 16770
white prepupae new
 
 16410
white prepupae 12hr
 
 16253
white prepupae 24hr
 
 17903
pupae 2d postWPP
 
 13438
pupae 3d postWPP
 
 10407
pupae 4d postWPP
 
 11637
adult male 01day
 
 11508
adult male 05day
 
 13235
adult male 30day
 
 12580
adult female 01day
 
 21396
adult female 05day
 
 18116
adult female 30day
 
 18897
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17931)
embryo 02-04hr
 (25163)
embryo 04-06hr
 (25918)
embryo 06-08hr
 (24681)
embryo 08-10hr
 (26816)
embryo 10-12hr
 (27869)
embryo 12-14hr
 (16855)
embryo 14-16hr
 (18625)
embryo 16-18hr
 (14654)
embryo 18-20hr
 (15346)
embryo 20-22hr
 (15188)
embryo 22-24hr
 (13854)
larva L1
 (25088)
larva L2
 (20511)
larva L3 12hr old
 (15686)
larva L3 puffstage 1-2
 (15228)
larva L3 puffstage 3-6
 (16380)
larva L3 puffstage 7-9
 (16770)
white prepupae new
 (16410)
white prepupae 12hr
 (16253)
white prepupae 24hr
 (17903)
pupae 2d postWPP
 (13438)
pupae 3d postWPP
 (10407)
pupae 4d postWPP
 (11637)
adult male 01day
 (11508)
adult male 05day
 (13235)
adult male 30day
 (12580)
adult female 01day
 (21396)
adult female 05day
 (18116)
adult female 30day
 (18897)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17931)
embryo 02-04hr
 (25163)
embryo 04-06hr
 (25918)
embryo 06-08hr
 (24681)
embryo 08-10hr
 (26816)
embryo 10-12hr
 (27869)
embryo 12-14hr
 (16855)
embryo 14-16hr
 (18625)
embryo 16-18hr
 (14654)
embryo 18-20hr
 (15346)
embryo 20-22hr
 (15188)
embryo 22-24hr
 (13854)
larva L1
 (25088)
larva L2
 (20511)
larva L3 12hr old
 (15686)
larva L3 puffstage 1-2
 (15228)
larva L3 puffstage 3-6
 (16380)
larva L3 puffstage 7-9
 (16770)
white prepupae new
 (16410)
white prepupae 12hr
 (16253)
white prepupae 24hr
 (17903)
pupae 2d postWPP
 (13438)
pupae 3d postWPP
 (10407)
pupae 4d postWPP
 (11637)
adult male 01day
 (11508)
adult male 05day
 (13235)
adult male 30day
 (12580)
adult female 01day
 (21396)
adult female 05day
 (18116)
adult female 30day
 (18897)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17931)
embryo 02-04hr
 (25163)
embryo 04-06hr
 (25918)
embryo 06-08hr
 (24681)
embryo 08-10hr
 (26816)
embryo 10-12hr
 (27869)
embryo 12-14hr
 (16855)
embryo 14-16hr
 (18625)
embryo 16-18hr
 (14654)
embryo 18-20hr
 (15346)
embryo 20-22hr
 (15188)
embryo 22-24hr
 (13854)
larva L1
 (25088)
larva L2
 (20511)
larva L3 12hr old
 (15686)
larva L3 puffstage 1-2
 (15228)
larva L3 puffstage 3-6
 (16380)
larva L3 puffstage 7-9
 (16770)
white prepupae new
 (16410)
white prepupae 12hr
 (16253)
white prepupae 24hr
 (17903)
pupae 2d postWPP
 (13438)
pupae 3d postWPP
 10407
pupae 4d postWPP
 (11637)
adult male 01day
 (11508)
adult male 05day
 (13235)
adult male 30day
 (12580)
adult female 01day
 (21396)
adult female 05day
 (18116)
adult female 30day
 (18897)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 17931
embryo 02-04hr
 
 25163
embryo 04-06hr
 
 25918
embryo 06-08hr
 
 24681
embryo 08-10hr
 
 26816
embryo 10-12hr
 
 27869
embryo 12-14hr
 
 16855
embryo 14-16hr
 
 18625
embryo 16-18hr
 
 14654
embryo 18-20hr
 
 15346
embryo 20-22hr
 
 15188
embryo 22-24hr
 
 13854
larva L1
 
 25088
larva L2
 
 20511
larva L3 12hr old
 
 15686
larva L3 puffstage 1-2
 
 15228
larva L3 puffstage 3-6
 
 16380
larva L3 puffstage 7-9
 
 16770
white prepupae new
 
 16410
white prepupae 12hr
 
 16253
white prepupae 24hr
 
 17903
pupae 2d postWPP
 
 13438
pupae 3d postWPP
 
 10407
pupae 4d postWPP
 
 11637
adult male 01day
 
 11508
adult male 05day
 
 13235
adult male 30day
 
 12580
adult female 01day
 
 21396
adult female 05day
 
 18116
adult female 30day
 
 18897
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0022023 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 17931
embryo 02-04hr
 
 25163
embryo 04-06hr
 
 25918
embryo 06-08hr
 
 24681
embryo 08-10hr
 
 26816
embryo 10-12hr
 
 27869
embryo 12-14hr
 
 16855
embryo 14-16hr
 
 18625
embryo 16-18hr
 
 14654
embryo 18-20hr
 
 15346
embryo 20-22hr
 
 15188
embryo 22-24hr
 
 13854
larva L1
 
 25088
larva L2
 
 20511
larva L3 12hr old
 
 15686
larva L3 puffstage 1-2
 
 15228
larva L3 puffstage 3-6
 
 16380
larva L3 puffstage 7-9
 
 16770
white prepupae new
 
 16410
white prepupae 12hr
 
 16253
white prepupae 24hr
 
 17903
pupae 2d postWPP
 
 13438
pupae 3d postWPP
 
 10407
pupae 4d postWPP
 
 11637
adult male 01day
 
 11508
adult male 05day
 
 13235
adult male 30day
 
 12580
adult female 01day
 
 21396
adult female 05day
 
 18116
adult female 30day
 
 18897
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17931)
embryo 02-04hr
 (25163)
embryo 04-06hr
 (25918)
embryo 06-08hr
 (24681)
embryo 08-10hr
 (26816)
embryo 10-12hr
 (27869)
embryo 12-14hr
 (16855)
embryo 14-16hr
 (18625)
embryo 16-18hr
 (14654)
embryo 18-20hr
 (15346)
embryo 20-22hr
 (15188)
embryo 22-24hr
 (13854)
larva L1
 (25088)
larva L2
 (20511)
larva L3 12hr old
 (15686)
larva L3 puffstage 1-2
 (15228)
larva L3 puffstage 3-6
 (16380)
larva L3 puffstage 7-9
 (16770)
white prepupae new
 (16410)
white prepupae 12hr
 (16253)
white prepupae 24hr
 (17903)
pupae 2d postWPP
 (13438)
pupae 3d postWPP
 (10407)
pupae 4d postWPP
 (11637)
adult male 01day
 (11508)
adult male 05day
 (13235)
adult male 30day
 (12580)
adult female 01day
 (21396)
adult female 05day
 (18116)
adult female 30day
 (18897)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17931)
embryo 02-04hr
 (25163)
embryo 04-06hr
 (25918)
embryo 06-08hr
 (24681)
embryo 08-10hr
 (26816)
embryo 10-12hr
 (27869)
embryo 12-14hr
 (16855)
embryo 14-16hr
 (18625)
embryo 16-18hr
 (14654)
embryo 18-20hr
 (15346)
embryo 20-22hr
 (15188)
embryo 22-24hr
 (13854)
larva L1
 (25088)
larva L2
 (20511)
larva L3 12hr old
 (15686)
larva L3 puffstage 1-2
 (15228)
larva L3 puffstage 3-6
 (16380)
larva L3 puffstage 7-9
 (16770)
white prepupae new
 (16410)
white prepupae 12hr
 (16253)
white prepupae 24hr
 (17903)
pupae 2d postWPP
 (13438)
pupae 3d postWPP
 (10407)
pupae 4d postWPP
 (11637)
adult male 01day
 (11508)
adult male 05day
 (13235)
adult male 30day
 (12580)
adult female 01day
 (21396)
adult female 05day
 (18116)
adult female 30day
 (18897)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 17931
embryo 02-04hr
 (25163)
embryo 04-06hr
 (25918)
embryo 06-08hr
 (24681)
embryo 08-10hr
 (26816)
embryo 10-12hr
 (27869)
embryo 12-14hr
 16855
embryo 14-16hr
 18625
embryo 16-18hr
 14654
embryo 18-20hr
 15346
embryo 20-22hr
 15188
embryo 22-24hr
 13854
larva L1
 (25088)
larva L2
 20511
larva L3 12hr old
 15686
larva L3 puffstage 1-2
 15228
larva L3 puffstage 3-6
 16380
larva L3 puffstage 7-9
 16770
white prepupae new
 16410
white prepupae 12hr
 16253
white prepupae 24hr
 17903
pupae 2d postWPP
 13438
pupae 3d postWPP
 10407
pupae 4d postWPP
 11637
adult male 01day
 11508
adult male 05day
 13235
adult male 30day
 12580
adult female 01day
 (21396)
adult female 05day
 18116
adult female 30day
 18897
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 17931
embryo 02-04hr
 
 25163
embryo 04-06hr
 
 25918
embryo 06-08hr
 
 24681
embryo 08-10hr
 
 26816
embryo 10-12hr
 
 27869
embryo 12-14hr
 
 16855
embryo 14-16hr
 
 18625
embryo 16-18hr
 
 14654
embryo 18-20hr
 
 15346
embryo 20-22hr
 
 15188
embryo 22-24hr
 
 13854
larva L1
 
 25088
larva L2
 
 20511
larva L3 12hr old
 
 15686
larva L3 puffstage 1-2
 
 15228
larva L3 puffstage 3-6
 
 16380
larva L3 puffstage 7-9
 
 16770
white prepupae new
 
 16410
white prepupae 12hr
 
 16253
white prepupae 24hr
 
 17903
pupae 2d postWPP
 
 13438
pupae 3d postWPP
 
 10407
pupae 4d postWPP
 
 11637
adult male 01day
 
 11508
adult male 05day
 
 13235
adult male 30day
 
 12580
adult female 01day
 
 21396
adult female 05day
 
 18116
adult female 30day
 
 18897
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0022023


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0022023
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0022023 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 1248.825
Larval Midgut
 
 775.1
Larval Hindgut
 
 1297.9
Larval Malpighian Tubules
 
 1130.5
Larval Fat Body
 
 1143.9
Larval Salivary Gland
 
 1736
Larval Trachea
 
 1342
Larval Carcass
 
 1296.55
Adult Head
 
 934.5
Adult Eye
 
 986.95
Adult Brain
 
 769.6
Adult Thoracic-Abdominal Ganglion
 
 944.6
Adult Crop
 
 1485.3
Adult Midgut
 
 920.9
Adult Hindgut
 
 1237.7
Adult Malpighian Tubules
 
 720
Adult Fat Body
 
 1724.4
Adult Salivary Gland
 
 1837
Adult Heart
 
 1202.95
Adult VirginFemale Spermatheca
 
 1166.5
Adult InseminatedFemale Spermatheca
 
 1217.1
Adult Ovary
 
 980
Adult Testis
 
 423.5
Adult Male Accessory Gland
 
 2418.1
Adult Carcass
 
 1062.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (1248.825)
Larval Midgut
 (775.1)
Larval Hindgut
 (1297.9)
Larval Malpighian Tubules
 (1130.5)
Larval Fat Body
 (1143.9)
Larval Salivary Gland
 (1736)
Larval Trachea
 (1342)
Larval Carcass
 (1296.55)
Adult Head
 (934.5)
Adult Eye
 (986.95)
Adult Brain
 (769.6)
Adult Thoracic-Abdominal Ganglion
 (944.6)
Adult Crop
 (1485.3)
Adult Midgut
 (920.9)
Adult Hindgut
 (1237.7)
Adult Malpighian Tubules
 (720)
Adult Fat Body
 (1724.4)
Adult Salivary Gland
 (1837)
Adult Heart
 (1202.95)
Adult VirginFemale Spermatheca
 (1166.5)
Adult InseminatedFemale Spermatheca
 (1217.1)
Adult Ovary
 (980)
Adult Testis
 
 423.5
Adult Male Accessory Gland
 (2418.1)
Adult Carcass
 (1062.8)
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 (1248.825)
Larval Midgut
 
 775.1
Larval Hindgut
 (1297.9)
Larval Malpighian Tubules
 (1130.5)
Larval Fat Body
 (1143.9)
Larval Salivary Gland
 (1736)
Larval Trachea
 (1342)
Larval Carcass
 (1296.55)
Adult Head
 
 934.5
Adult Eye
 
 986.95
Adult Brain
 
 769.6
Adult Thoracic-Abdominal Ganglion
 
 944.6
Adult Crop
 (1485.3)
Adult Midgut
 
 920.9
Adult Hindgut
 (1237.7)
Adult Malpighian Tubules
 
 720
Adult Fat Body
 (1724.4)
Adult Salivary Gland
 (1837)
Adult Heart
 (1202.95)
Adult VirginFemale Spermatheca
 (1166.5)
Adult InseminatedFemale Spermatheca
 (1217.1)
Adult Ovary
 
 980
Adult Testis
 
 423.5
Adult Male Accessory Gland
 (2418.1)
Adult Carcass
 1062.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 1248.825
Larval Midgut
 
 775.1
Larval Hindgut
 
 1297.9
Larval Malpighian Tubules
 
 1130.5
Larval Fat Body
 
 1143.9
Larval Salivary Gland
 
 1736
Larval Trachea
 
 1342
Larval Carcass
 
 1296.55
Adult Head
 
 934.5
Adult Eye
 
 986.95
Adult Brain
 
 769.6
Adult Thoracic-Abdominal Ganglion
 
 944.6
Adult Crop
 
 1485.3
Adult Midgut
 
 920.9
Adult Hindgut
 
 1237.7
Adult Malpighian Tubules
 
 720
Adult Fat Body
 
 1724.4
Adult Salivary Gland
 
 1837
Adult Heart
 
 1202.95
Adult VirginFemale Spermatheca
 
 1166.5
Adult InseminatedFemale Spermatheca
 
 1217.1
Adult Ovary
 
 980
Adult Testis
 
 423.5
Adult Male Accessory Gland
 
 2418.1
Adult Carcass
 
 1062.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0022023 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 1248.825
Larval Midgut
 
 775.1
Larval Hindgut
 
 1297.9
Larval Malpighian Tubules
 
 1130.5
Larval Fat Body
 
 1143.9
Larval Salivary Gland
 
 1736
Larval Trachea
 
 1342
Larval Carcass
 
 1296.55
Adult Head
 
 934.5
Adult Eye
 
 986.95
Adult Brain
 
 769.6
Adult Thoracic-Abdominal Ganglion
 
 944.6
Adult Crop
 
 1485.3
Adult Midgut
 
 920.9
Adult Hindgut
 
 1237.7
Adult Malpighian Tubules
 
 720
Adult Fat Body
 
 1724.4
Adult Salivary Gland
 
 1837
Adult Heart
 
 1202.95
Adult VirginFemale Spermatheca
 
 1166.5
Adult InseminatedFemale Spermatheca
 
 1217.1
Adult Ovary
 
 980
Adult Testis
 
 423.5
Adult Male Accessory Gland
 
 2418.1
Adult Carcass
 
 1062.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (1248.825)
Larval Midgut
 775.1
Larval Hindgut
 (1297.9)
Larval Malpighian Tubules
 (1130.5)
Larval Fat Body
 (1143.9)
Larval Salivary Gland
 (1736)
Larval Trachea
 (1342)
Larval Carcass
 (1296.55)
Adult Head
 (934.5)
Adult Eye
 (986.95)
Adult Brain
 769.6
Adult Thoracic-Abdominal Ganglion
 (944.6)
Adult Crop
 (1485.3)
Adult Midgut
 (920.9)
Adult Hindgut
 (1237.7)
Adult Malpighian Tubules
 720
Adult Fat Body
 (1724.4)
Adult Salivary Gland
 (1837)
Adult Heart
 (1202.95)
Adult VirginFemale Spermatheca
 (1166.5)
Adult InseminatedFemale Spermatheca
 (1217.1)
Adult Ovary
 (980)
Adult Testis
 
 423.5
Adult Male Accessory Gland
 (2418.1)
Adult Carcass
 (1062.8)
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 1248.825
Larval Midgut
 
 775.1
Larval Hindgut
 1297.9
Larval Malpighian Tubules
 1130.5
Larval Fat Body
 1143.9
Larval Salivary Gland
 (1736)
Larval Trachea
 1342
Larval Carcass
 1296.55
Adult Head
 
 934.5
Adult Eye
 
 986.95
Adult Brain
 
 769.6
Adult Thoracic-Abdominal Ganglion
 
 944.6
Adult Crop
 1485.3
Adult Midgut
 
 920.9
Adult Hindgut
 1237.7
Adult Malpighian Tubules
 
 720
Adult Fat Body
 (1724.4)
Adult Salivary Gland
 (1837)
Adult Heart
 1202.95
Adult VirginFemale Spermatheca
 1166.5
Adult InseminatedFemale Spermatheca
 1217.1
Adult Ovary
 
 980
Adult Testis
 
 423.5
Adult Male Accessory Gland
 (2418.1)
Adult Carcass
 1062.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 1248.825
Larval Midgut
 
 775.1
Larval Hindgut
 
 1297.9
Larval Malpighian Tubules
 
 1130.5
Larval Fat Body
 
 1143.9
Larval Salivary Gland
 
 1736
Larval Trachea
 
 1342
Larval Carcass
 
 1296.55
Adult Head
 
 934.5
Adult Eye
 
 986.95
Adult Brain
 
 769.6
Adult Thoracic-Abdominal Ganglion
 
 944.6
Adult Crop
 
 1485.3
Adult Midgut
 
 920.9
Adult Hindgut
 
 1237.7
Adult Malpighian Tubules
 
 720
Adult Fat Body
 
 1724.4
Adult Salivary Gland
 
 1837
Adult Heart
 
 1202.95
Adult VirginFemale Spermatheca
 
 1166.5
Adult InseminatedFemale Spermatheca
 
 1217.1
Adult Ovary
 
 980
Adult Testis
 
 423.5
Adult Male Accessory Gland
 
 2418.1
Adult Carcass
 
 1062.8
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 934.5
 
NA 
Eye
 
 986.95
 
NA 
Brain
 
 769.6
 
1248.825 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 944.6
 
NA 
Crop
 
 1485.3
 
775.1 
Midgut
 
 920.9
 
1297.9 
Hindgut
 
 1237.7
 
1130.5 
Malpighian Tubules
 
 720
 
1143.9 
Fat Body
 
 1724.4
 
1736 
Salivary Gland
 
 1837
 
NA 
Heart
 
 1202.95
 
1342 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 1166.5
 
NA 
InseminatedFemale Spermatheca
 
 1217.1
 
NA 
Ovary
 
 980
 
NA 
Testis
 
 423.5
 
NA 
Male Accessory Gland
 
 2418.1
 
1296.55 
Carcass
 
 1062.8

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
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Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
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hide Summary of Allele Phenotypes
Lethality
Allele
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Allele
Phenotype manifest in
Allele
hide Classical Alleles ( 5 )
For All Classical Alleles Show

Allele of eIF-3p40ClassMutagenStocksKnown lesion
eIF-3p40k090032 --
eIF-3p40k093061 --
eIF-3p40k166151 --
eIF-3p40NP0834
1 --
eIF-3p40NP5205
1 --
hide Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show

Allele of eIF-3p40ClassMutagenStocksKnown lesion
eIF-3p40GD141272 Yes
eIF-3p40KK1023441 Yes
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Not disrupted in
Disrupted in
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
UAS construct
Insertions
Type of insertions
Name
Expression data
insertion of enhancer trap binary system
hide Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
hide Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
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CV term
References
inferred from mutant phenotype
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hide Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term
References
inferred from sequence or structural similarity
inferred from sequence or structural similarity with UniProtKB:O15372
Biological Process
CV term
References
inferred from sequence or structural similarity
inferred from sequence or structural similarity with UniProtKB:O15372
Cellular Component
CV term
References
inferred from sequence or structural similarity
inferred from sequence or structural similarity
inferred from sequence or structural similarity with UniProtKB:O15372
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Protein-protein
Interacting group
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Interacts with
Please look at the allele data for full details of the genetic interactions
eIF-3p40 allele
Gene
References
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Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
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hide Stocks Listed in FlyBase ( 9 )
Bloomington
Kyoto
VDRC
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Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 92 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
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hide Relationship to Other Genes
Source for database identity of
Source for identity of: BcDNA:GM14618 CG9124
Source for database merge of
Source for merge of: eIF-3p40 BcDNA:GM14618
Additional comments
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Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Mov34/MPN/PAD-1 (IPR000555)
Linkouts
BioGRID - A database of protein and genetic interactions
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym
BcDNA:GM14618
 
eIF-3p40
 
eIF3-S3
Name Synonym
Eukaryotic initiation factor 3 p40 subunit
Secondary FlyBase IDs
  • FBgn0027910
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All research papers listed in FlyBase were published before 2010