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Gene Dmel\eIF-3p40

General Information
Symbol	Dmel\eIF-3p40	Species	D. melanogaster
Name	Eukaryotic initiation factor 3 p40 subunit	Annotation symbol	CG9124
Feature type	protein_coding_gene	FlyBase ID	FBgn0022023
Gene Model Status	Current	Stock availability	9 publicly available
Also Known As	l(2)k09003
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	25C3-25C3	Sequence location	2L:5,051,193..5,053,094 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Eukaryotic initiation factor 3 p40 subunit is referred to in FlyBase by the symbol Dmel\eIF-3p40 (CG9124, FBgn0022023). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 8 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: JAB1/Mov34/MPN/PAD-1. Summary of modENCODE Temporal Expression Profile: Very high expression at all stages of development. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1625078_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of eIF-3p40. Gene sequence location is 2L:5051193..5053094.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Controlled Vocabulary Terms positive regulation of Notch signaling pathway
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 25C3-25C3   Limits computationally determined from genome sequence between P{lacW}vkgk16721&P{lacW}Cg25Ck00405 and P{lacW}l(2)k11206k11206
Experimentally Determined Cytological Location
Cytogenetic map Notes References 25C1-25C2   (determined by in situ hybridisation)   (Spradling et al., 1999) 25C1-25C2     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\eIF-3p40 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) eIF-3p40-RA FBtr0079030  NM_080095   1496   338 eIF-3p40-RB FBtr0079031  NM_205909   1182   338
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein eIF-3p40-PA   FBpp0078667   38.4   338   6.01     NP_524834   AAF52210 eIF-3p40-PB   FBpp0089133   38.4   338   6.01     NP_995631   AAS64639
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • JAB1/Mov34/MPN/PAD-1 (IPR000555) Eukaryotic translation initiation factor 3 subunit H (IPR027524)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246922   AA263296   AA391268   AA439776   AA540439   AA696590   AA802236   AA821117   AE014134 AAF52210   AE014134 AAS64639   AF160896 AAD46836   AI106684   AI108238   AI110127   AI134478   AI134808   AI135264   AI135270   AI387482   AI389384   AI406085   AI457050   AI518104   AI519656   AI519669   AI534203   AQ025877   AW941397   BF488750   BF493643   BF499290   BF502676   BF505441   BG638277   BG638947   BG640123   BI162511   BI162512   BI162582   BI162583   BI215360   BI230783   BI231995   BI236465   BI237114   BI239627   BI354311   BI354380   BI358613   BI358662   BI358703   BI368461   BI563380   BI564707   BI566248   BI567380   BI567549   BI574517   BI575033   BI581277   BI582132   BI582712   BI584587   BI586963   BI605594   BI605831   BI616233   BI623675   BI625937   BP543921   BP543922   BP550657   BP550658   BP555753   BP555754   BP557691   BP557692   BP559661   BP559662   BT071794   BX005705   BX006279   BX008276   BX018289   BX019704   BX023100   BX028312   BX030752   BX032039   BX034231   BX035452   BX035884   BX052862   BX055180   BX055823   BX055908   BX057750   BX062653   BX064052   BX065409   BX067748   BX069074   BX070048   CK604236   CK604952   CK604953   CK605029   CK605280   CK658878   CO178348   CO184125   CO186552   CO189993   CO265274   CO272445   CO279618   CO292852   CO294352   CO296516   CO305039   CO314358   CO315161   CO318545   CO335770   CO336651   CO337878   CO338228   CO338314   EC057945   EC060350   EC061318   EC066829   EC069768   EC077212   EC201731   EC201794   EC206264   EC210452   EC214624   EC216028   EC222346   EC225971   EC244662   EC248858   EC261741   EC262362   EC264084   EC267108   EC268000   ES689001   EV579967
UniProtKB/Swiss-Prot	Q9U9Q4
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1248.825 Larval Midgut    775.1 Larval Hindgut    1297.9 Larval Malpighian Tubules    1130.5 Larval Fat Body    1143.9 Larval Salivary Gland    1736 Larval Trachea    1342 Larval Carcass    1296.55 Adult Head    934.5 Adult Eye    986.95 Adult Brain    769.6 Adult Thoracic-Abdominal Ganglion    944.6 Adult Crop    1485.3 Adult Midgut    920.9 Adult Hindgut    1237.7 Adult Malpighian Tubules    720 Adult Fat Body    1724.4 Adult Salivary Gland    1837 Adult Heart    1202.95 Adult VirginFemale Spermatheca    1166.5 Adult InseminatedFemale Spermatheca    1217.1 Adult Ovary    980 Adult Testis    423.5 Adult Male Accessory Gland    2418.1 Adult Carcass    1062.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1248.825) Larval Midgut  (775.1) Larval Hindgut  (1297.9) Larval Malpighian Tubules  (1130.5) Larval Fat Body  (1143.9) Larval Salivary Gland  (1736) Larval Trachea  (1342) Larval Carcass  (1296.55) Adult Head  (934.5) Adult Eye  (986.95) Adult Brain  (769.6) Adult Thoracic-Abdominal Ganglion  (944.6) Adult Crop  (1485.3) Adult Midgut  (920.9) Adult Hindgut  (1237.7) Adult Malpighian Tubules  (720) Adult Fat Body  (1724.4) Adult Salivary Gland  (1837) Adult Heart  (1202.95) Adult VirginFemale Spermatheca  (1166.5) Adult InseminatedFemale Spermatheca  (1217.1) Adult Ovary  (980) Adult Testis    423.5 Adult Male Accessory Gland  (2418.1) Adult Carcass  (1062.8) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1248.825) Larval Midgut    775.1 Larval Hindgut  (1297.9) Larval Malpighian Tubules  (1130.5) Larval Fat Body  (1143.9) Larval Salivary Gland  (1736) Larval Trachea  (1342) Larval Carcass  (1296.55) Adult Head    934.5 Adult Eye    986.95 Adult Brain    769.6 Adult Thoracic-Abdominal Ganglion    944.6 Adult Crop  (1485.3) Adult Midgut    920.9 Adult Hindgut  (1237.7) Adult Malpighian Tubules    720 Adult Fat Body  (1724.4) Adult Salivary Gland  (1837) Adult Heart  (1202.95) Adult VirginFemale Spermatheca  (1166.5) Adult InseminatedFemale Spermatheca  (1217.1) Adult Ovary    980 Adult Testis    423.5 Adult Male Accessory Gland  (2418.1) Adult Carcass  1062.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1248.825 Larval Midgut    775.1 Larval Hindgut    1297.9 Larval Malpighian Tubules    1130.5 Larval Fat Body    1143.9 Larval Salivary Gland    1736 Larval Trachea    1342 Larval Carcass    1296.55 Adult Head    934.5 Adult Eye    986.95 Adult Brain    769.6 Adult Thoracic-Abdominal Ganglion    944.6 Adult Crop    1485.3 Adult Midgut    920.9 Adult Hindgut    1237.7 Adult Malpighian Tubules    720 Adult Fat Body    1724.4 Adult Salivary Gland    1837 Adult Heart    1202.95 Adult VirginFemale Spermatheca    1166.5 Adult InseminatedFemale Spermatheca    1217.1 Adult Ovary    980 Adult Testis    423.5 Adult Male Accessory Gland    2418.1 Adult Carcass    1062.8 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1248.825 Larval Midgut    775.1 Larval Hindgut    1297.9 Larval Malpighian Tubules    1130.5 Larval Fat Body    1143.9 Larval Salivary Gland    1736 Larval Trachea    1342 Larval Carcass    1296.55 Adult Head    934.5 Adult Eye    986.95 Adult Brain    769.6 Adult Thoracic-Abdominal Ganglion    944.6 Adult Crop    1485.3 Adult Midgut    920.9 Adult Hindgut    1237.7 Adult Malpighian Tubules    720 Adult Fat Body    1724.4 Adult Salivary Gland    1837 Adult Heart    1202.95 Adult VirginFemale Spermatheca    1166.5 Adult InseminatedFemale Spermatheca    1217.1 Adult Ovary    980 Adult Testis    423.5 Adult Male Accessory Gland    2418.1 Adult Carcass    1062.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1248.825) Larval Midgut  775.1 Larval Hindgut  (1297.9) Larval Malpighian Tubules  (1130.5) Larval Fat Body  (1143.9) Larval Salivary Gland  (1736) Larval Trachea  (1342) Larval Carcass  (1296.55) Adult Head  (934.5) Adult Eye  (986.95) Adult Brain  769.6 Adult Thoracic-Abdominal Ganglion  (944.6) Adult Crop  (1485.3) Adult Midgut  (920.9) Adult Hindgut  (1237.7) Adult Malpighian Tubules  720 Adult Fat Body  (1724.4) Adult Salivary Gland  (1837) Adult Heart  (1202.95) Adult VirginFemale Spermatheca  (1166.5) Adult InseminatedFemale Spermatheca  (1217.1) Adult Ovary  (980) Adult Testis    423.5 Adult Male Accessory Gland  (2418.1) Adult Carcass  (1062.8) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1248.825 Larval Midgut    775.1 Larval Hindgut  1297.9 Larval Malpighian Tubules  1130.5 Larval Fat Body  1143.9 Larval Salivary Gland  (1736) Larval Trachea  1342 Larval Carcass  1296.55 Adult Head    934.5 Adult Eye    986.95 Adult Brain    769.6 Adult Thoracic-Abdominal Ganglion    944.6 Adult Crop  1485.3 Adult Midgut    920.9 Adult Hindgut  1237.7 Adult Malpighian Tubules    720 Adult Fat Body  (1724.4) Adult Salivary Gland  (1837) Adult Heart  1202.95 Adult VirginFemale Spermatheca  1166.5 Adult InseminatedFemale Spermatheca  1217.1 Adult Ovary    980 Adult Testis    423.5 Adult Male Accessory Gland  (2418.1) Adult Carcass  1062.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1248.825 Larval Midgut    775.1 Larval Hindgut    1297.9 Larval Malpighian Tubules    1130.5 Larval Fat Body    1143.9 Larval Salivary Gland    1736 Larval Trachea    1342 Larval Carcass    1296.55 Adult Head    934.5 Adult Eye    986.95 Adult Brain    769.6 Adult Thoracic-Abdominal Ganglion    944.6 Adult Crop    1485.3 Adult Midgut    920.9 Adult Hindgut    1237.7 Adult Malpighian Tubules    720 Adult Fat Body    1724.4 Adult Salivary Gland    1837 Adult Heart    1202.95 Adult VirginFemale Spermatheca    1166.5 Adult InseminatedFemale Spermatheca    1217.1 Adult Ovary    980 Adult Testis    423.5 Adult Male Accessory Gland    2418.1 Adult Carcass    1062.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    934.5   NA  Eye    986.95   NA  Brain    769.6   1248.825  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    944.6   NA  Crop    1485.3   775.1  Midgut    920.9   1297.9  Hindgut    1237.7   1130.5  Malpighian Tubules    720   1143.9  Fat Body    1724.4   1736  Salivary Gland    1837   NA  Heart    1202.95   1342  Trachea    NA   NA  VirginFemale Spermatheca    1166.5   NA  InseminatedFemale Spermatheca    1217.1   NA  Ovary    980   NA  Testis    423.5   NA  Male Accessory Gland    2418.1   1296.55  Carcass    1062.8 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    145 central nervous system, pupae P8    82 head, virgin 1-day female    77 head, virgin 4-day female    92 head, virgin 20-day female    92 head, mated 1-day female    74 head, mated 4-day female    81 head, mated 20-day female    75 head, mated 1-day male    84 head, mated 4-day male    76 head, mated 20-day male    91 salivary gland, larvae L3 wandering    86 salivary gland, white prepupae    243 digestive system, larvae L3 wandering    121 digestive system, 1-day adult    84 digestive system, 4-day adult    79 digestive system, 20-day adult    88 fat body, larvae L3 wandering    66 fat body, white prepupae    78 fat body, pupae P8    157 carcass, larvae L3 wandering    135 carcass, 1-day adult    60 carcass, 4-day adult    76 carcass, 20-day adult    74 ovary, virgin 4-day female    127 ovary, mated 4-day female    148 testis, mated 4-day male    101 accessory gland, mated 4-day male    149 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  (145) central nervous system, pupae P8  (82) head, virgin 1-day female  (77) head, virgin 4-day female  (92) head, virgin 20-day female  (92) head, mated 1-day female  (74) head, mated 4-day female  (81) head, mated 20-day female  (75) head, mated 1-day male  (84) head, mated 4-day male  (76) head, mated 20-day male  (91) salivary gland, larvae L3 wandering  (86) salivary gland, white prepupae  (243) digestive system, larvae L3 wandering  (121) digestive system, 1-day adult  (84) digestive system, 4-day adult  (79) digestive system, 20-day adult  (88) fat body, larvae L3 wandering  (66) fat body, white prepupae  (78) fat body, pupae P8  (157) carcass, larvae L3 wandering  (135) carcass, 1-day adult  (60) carcass, 4-day adult  (76) carcass, 20-day adult  (74) ovary, virgin 4-day female  (127) ovary, mated 4-day female  (148) testis, mated 4-day male  (101) accessory gland, mated 4-day male  (149) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  (145) central nervous system, pupae P8    82 head, virgin 1-day female    77 head, virgin 4-day female    92 head, virgin 20-day female    92 head, mated 1-day female    74 head, mated 4-day female    81 head, mated 20-day female    75 head, mated 1-day male    84 head, mated 4-day male    76 head, mated 20-day male    91 salivary gland, larvae L3 wandering    86 salivary gland, white prepupae  (243) digestive system, larvae L3 wandering  (121) digestive system, 1-day adult    84 digestive system, 4-day adult    79 digestive system, 20-day adult    88 fat body, larvae L3 wandering    66 fat body, white prepupae    78 fat body, pupae P8  (157) carcass, larvae L3 wandering  (135) carcass, 1-day adult    60 carcass, 4-day adult    76 carcass, 20-day adult    74 ovary, virgin 4-day female  (127) ovary, mated 4-day female  (148) testis, mated 4-day male  101 accessory gland, mated 4-day male  (149) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    145 central nervous system, pupae P8    82 head, virgin 1-day female    77 head, virgin 4-day female    92 head, virgin 20-day female    92 head, mated 1-day female    74 head, mated 4-day female    81 head, mated 20-day female    75 head, mated 1-day male    84 head, mated 4-day male    76 head, mated 20-day male    91 salivary gland, larvae L3 wandering    86 salivary gland, white prepupae    243 digestive system, larvae L3 wandering    121 digestive system, 1-day adult    84 digestive system, 4-day adult    79 digestive system, 20-day adult    88 fat body, larvae L3 wandering    66 fat body, white prepupae    78 fat body, pupae P8    157 carcass, larvae L3 wandering    135 carcass, 1-day adult    60 carcass, 4-day adult    76 carcass, 20-day adult    74 ovary, virgin 4-day female    127 ovary, mated 4-day female    148 testis, mated 4-day male    101 accessory gland, mated 4-day male    149 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    145 central nervous system, pupae P8    82 head, virgin 1-day female    77 head, virgin 4-day female    92 head, virgin 20-day female    92 head, mated 1-day female    74 head, mated 4-day female    81 head, mated 20-day female    75 head, mated 1-day male    84 head, mated 4-day male    76 head, mated 20-day male    91 salivary gland, larvae L3 wandering    86 salivary gland, white prepupae    243 digestive system, larvae L3 wandering    121 digestive system, 1-day adult    84 digestive system, 4-day adult    79 digestive system, 20-day adult    88 fat body, larvae L3 wandering    66 fat body, white prepupae    78 fat body, pupae P8    157 carcass, larvae L3 wandering    135 carcass, 1-day adult    60 carcass, 4-day adult    76 carcass, 20-day adult    74 ovary, virgin 4-day female    127 ovary, mated 4-day female    148 testis, mated 4-day male    101 accessory gland, mated 4-day male    149 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  (145) central nervous system, pupae P8  (82) head, virgin 1-day female  (77) head, virgin 4-day female  (92) head, virgin 20-day female  (92) head, mated 1-day female  (74) head, mated 4-day female  (81) head, mated 20-day female  (75) head, mated 1-day male  (84) head, mated 4-day male  (76) head, mated 20-day male  (91) salivary gland, larvae L3 wandering  (86) salivary gland, white prepupae  (243) digestive system, larvae L3 wandering  (121) digestive system, 1-day adult  (84) digestive system, 4-day adult  (79) digestive system, 20-day adult  (88) fat body, larvae L3 wandering  (66) fat body, white prepupae  (78) fat body, pupae P8  (157) carcass, larvae L3 wandering  (135) carcass, 1-day adult  (60) carcass, 4-day adult  (76) carcass, 20-day adult  (74) ovary, virgin 4-day female  (127) ovary, mated 4-day female  (148) testis, mated 4-day male  (101) accessory gland, mated 4-day male  (149) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (155) central nervous system, larvae L3  (145) central nervous system, pupae P8    82 head, virgin 1-day female    77 head, virgin 4-day female    92 head, virgin 20-day female    92 head, mated 1-day female    74 head, mated 4-day female    81 head, mated 20-day female    75 head, mated 1-day male    84 head, mated 4-day male    76 head, mated 20-day male    91 salivary gland, larvae L3 wandering    86 salivary gland, white prepupae  (243) digestive system, larvae L3 wandering  121 digestive system, 1-day adult    84 digestive system, 4-day adult    79 digestive system, 20-day adult    88 fat body, larvae L3 wandering    66 fat body, white prepupae    78 fat body, pupae P8  (157) carcass, larvae L3 wandering  135 carcass, 1-day adult    60 carcass, 4-day adult    76 carcass, 20-day adult    74 ovary, virgin 4-day female  127 ovary, mated 4-day female  (148) testis, mated 4-day male  101 accessory gland, mated 4-day male  (149) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    155 central nervous system, larvae L3    145 central nervous system, pupae P8    82 head, virgin 1-day female    77 head, virgin 4-day female    92 head, virgin 20-day female    92 head, mated 1-day female    74 head, mated 4-day female    81 head, mated 20-day female    75 head, mated 1-day male    84 head, mated 4-day male    76 head, mated 20-day male    91 salivary gland, larvae L3 wandering    86 salivary gland, white prepupae    243 digestive system, larvae L3 wandering    121 digestive system, 1-day adult    84 digestive system, 4-day adult    79 digestive system, 20-day adult    88 fat body, larvae L3 wandering    66 fat body, white prepupae    78 fat body, pupae P8    157 carcass, larvae L3 wandering    135 carcass, 1-day adult    60 carcass, 4-day adult    76 carcass, 20-day adult    74 ovary, virgin 4-day female    127 ovary, mated 4-day female    148 testis, mated 4-day male    101 accessory gland, mated 4-day male    149 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Very high expression at all stages of development. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    244 embryo 02-04hr    343 embryo 04-06hr    353 embryo 06-08hr    336 embryo 08-10hr    365 embryo 10-12hr    380 embryo 12-14hr    230 embryo 14-16hr    254 embryo 16-18hr    200 embryo 18-20hr    209 embryo 20-22hr    207 embryo 22-24hr    189 larva L1    342 larva L2    279 larva L3 12hr old    214 larva L3 puffstage 1-2    207 larva L3 puffstage 3-6    223 larva L3 puffstage 7-9    228 white prepupae new    224 white prepupae 12hr    221 white prepupae 24hr    244 pupae 2d postWPP    183 pupae 3d postWPP    142 pupae 4d postWPP    159 adult male 01day    157 adult male 05day    180 adult male 30day    171 adult female 01day    291 adult female 05day    247 adult female 30day    257 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (244) embryo 02-04hr  (343) embryo 04-06hr  (353) embryo 06-08hr  (336) embryo 08-10hr  (365) embryo 10-12hr  (380) embryo 12-14hr  (230) embryo 14-16hr  (254) embryo 16-18hr  (200) embryo 18-20hr  (209) embryo 20-22hr  (207) embryo 22-24hr  (189) larva L1  (342) larva L2  (279) larva L3 12hr old  (214) larva L3 puffstage 1-2  (207) larva L3 puffstage 3-6  (223) larva L3 puffstage 7-9  (228) white prepupae new  (224) white prepupae 12hr  (221) white prepupae 24hr  (244) pupae 2d postWPP  (183) pupae 3d postWPP  (142) pupae 4d postWPP  (159) adult male 01day  (157) adult male 05day  (180) adult male 30day  (171) adult female 01day  (291) adult female 05day  (247) adult female 30day  (257) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (244) embryo 02-04hr  (343) embryo 04-06hr  (353) embryo 06-08hr  (336) embryo 08-10hr  (365) embryo 10-12hr  (380) embryo 12-14hr  (230) embryo 14-16hr  (254) embryo 16-18hr  (200) embryo 18-20hr  (209) embryo 20-22hr  (207) embryo 22-24hr  (189) larva L1  (342) larva L2  (279) larva L3 12hr old  (214) larva L3 puffstage 1-2  (207) larva L3 puffstage 3-6  (223) larva L3 puffstage 7-9  (228) white prepupae new  (224) white prepupae 12hr  (221) white prepupae 24hr  (244) pupae 2d postWPP  (183) pupae 3d postWPP  (142) pupae 4d postWPP  (159) adult male 01day  (157) adult male 05day  (180) adult male 30day  (171) adult female 01day  (291) adult female 05day  (247) adult female 30day  (257) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    244 embryo 02-04hr    343 embryo 04-06hr    353 embryo 06-08hr    336 embryo 08-10hr    365 embryo 10-12hr    380 embryo 12-14hr    230 embryo 14-16hr    254 embryo 16-18hr    200 embryo 18-20hr    209 embryo 20-22hr    207 embryo 22-24hr    189 larva L1    342 larva L2    279 larva L3 12hr old    214 larva L3 puffstage 1-2    207 larva L3 puffstage 3-6    223 larva L3 puffstage 7-9    228 white prepupae new    224 white prepupae 12hr    221 white prepupae 24hr    244 pupae 2d postWPP    183 pupae 3d postWPP    142 pupae 4d postWPP    159 adult male 01day    157 adult male 05day    180 adult male 30day    171 adult female 01day    291 adult female 05day    247 adult female 30day    257 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    244 embryo 02-04hr    343 embryo 04-06hr    353 embryo 06-08hr    336 embryo 08-10hr    365 embryo 10-12hr    380 embryo 12-14hr    230 embryo 14-16hr    254 embryo 16-18hr    200 embryo 18-20hr    209 embryo 20-22hr    207 embryo 22-24hr    189 larva L1    342 larva L2    279 larva L3 12hr old    214 larva L3 puffstage 1-2    207 larva L3 puffstage 3-6    223 larva L3 puffstage 7-9    228 white prepupae new    224 white prepupae 12hr    221 white prepupae 24hr    244 pupae 2d postWPP    183 pupae 3d postWPP    142 pupae 4d postWPP    159 adult male 01day    157 adult male 05day    180 adult male 30day    171 adult female 01day    291 adult female 05day    247 adult female 30day    257 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (244) embryo 02-04hr  (343) embryo 04-06hr  (353) embryo 06-08hr  (336) embryo 08-10hr  (365) embryo 10-12hr  (380) embryo 12-14hr  (230) embryo 14-16hr  (254) embryo 16-18hr  (200) embryo 18-20hr  (209) embryo 20-22hr  (207) embryo 22-24hr  (189) larva L1  (342) larva L2  (279) larva L3 12hr old  (214) larva L3 puffstage 1-2  (207) larva L3 puffstage 3-6  (223) larva L3 puffstage 7-9  (228) white prepupae new  (224) white prepupae 12hr  (221) white prepupae 24hr  (244) pupae 2d postWPP  (183) pupae 3d postWPP  (142) pupae 4d postWPP  (159) adult male 01day  (157) adult male 05day  (180) adult male 30day  (171) adult female 01day  (291) adult female 05day  (247) adult female 30day  (257) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (244) embryo 02-04hr  (343) embryo 04-06hr  (353) embryo 06-08hr  (336) embryo 08-10hr  (365) embryo 10-12hr  (380) embryo 12-14hr  (230) embryo 14-16hr  (254) embryo 16-18hr  (200) embryo 18-20hr  (209) embryo 20-22hr  (207) embryo 22-24hr  (189) larva L1  (342) larva L2  (279) larva L3 12hr old  (214) larva L3 puffstage 1-2  (207) larva L3 puffstage 3-6  (223) larva L3 puffstage 7-9  (228) white prepupae new  (224) white prepupae 12hr  (221) white prepupae 24hr  (244) pupae 2d postWPP  (183) pupae 3d postWPP  142 pupae 4d postWPP  (159) adult male 01day  (157) adult male 05day  (180) adult male 30day  (171) adult female 01day  (291) adult female 05day  (247) adult female 30day  (257) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    244 embryo 02-04hr    343 embryo 04-06hr    353 embryo 06-08hr    336 embryo 08-10hr    365 embryo 10-12hr    380 embryo 12-14hr    230 embryo 14-16hr    254 embryo 16-18hr    200 embryo 18-20hr    209 embryo 20-22hr    207 embryo 22-24hr    189 larva L1    342 larva L2    279 larva L3 12hr old    214 larva L3 puffstage 1-2    207 larva L3 puffstage 3-6    223 larva L3 puffstage 7-9    228 white prepupae new    224 white prepupae 12hr    221 white prepupae 24hr    244 pupae 2d postWPP    183 pupae 3d postWPP    142 pupae 4d postWPP    159 adult male 01day    157 adult male 05day    180 adult male 30day    171 adult female 01day    291 adult female 05day    247 adult female 30day    257 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    320 Schneider line 2 Sg4    210 embryonic 1182-4H    277 embryonic GM2    160 embryonic Kc167    137 embryonic S1    206 embryonic S3    124 leg disc CME L1    205 wing disc CME-W2    140 wing disc ML-DmD8    161 wing disc ML-DmD9    240 wing disc ML-DmD16-c3    92 wing disc ML-DmD21    362 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    169 eye-antennal disc ML-DmD11    218 antennal disc ML-DmD20-c5    233 mixed discs ML-DmD4-c1    212 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    141 tumorous blood cells mbn2    121 ovary fGS/OSS    182 ovary OSC    105 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (320) Schneider line 2 Sg4  (210) embryonic 1182-4H  (277) embryonic GM2  (160) embryonic Kc167  (137) embryonic S1  (206) embryonic S3  (124) leg disc CME L1  (205) wing disc CME-W2  (140) wing disc ML-DmD8  (161) wing disc ML-DmD9  (240) wing disc ML-DmD16-c3  (92) wing disc ML-DmD21  (362) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (169) eye-antennal disc ML-DmD11  (218) antennal disc ML-DmD20-c5  (233) mixed discs ML-DmD4-c1  (212) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2  (141) tumorous blood cells mbn2  (121) ovary fGS/OSS  (182) ovary OSC  (105) ovary OSS  (68) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (320) Schneider line 2 Sg4  (210) embryonic 1182-4H  (277) embryonic GM2  (160) embryonic Kc167  (137) embryonic S1  (206) embryonic S3  (124) leg disc CME L1  (205) wing disc CME-W2  (140) wing disc ML-DmD8  (161) wing disc ML-DmD9  (240) wing disc ML-DmD16-c3    92 wing disc ML-DmD21  (362) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (169) eye-antennal disc ML-DmD11  (218) antennal disc ML-DmD20-c5  (233) mixed discs ML-DmD4-c1  (212) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2  (141) tumorous blood cells mbn2  (121) ovary fGS/OSS  (182) ovary OSC  105 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    320 Schneider line 2 Sg4    210 embryonic 1182-4H    277 embryonic GM2    160 embryonic Kc167    137 embryonic S1    206 embryonic S3    124 leg disc CME L1    205 wing disc CME-W2    140 wing disc ML-DmD8    161 wing disc ML-DmD9    240 wing disc ML-DmD16-c3    92 wing disc ML-DmD21    362 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    169 eye-antennal disc ML-DmD11    218 antennal disc ML-DmD20-c5    233 mixed discs ML-DmD4-c1    212 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    141 tumorous blood cells mbn2    121 ovary fGS/OSS    182 ovary OSC    105 ovary OSS    68 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    320 Schneider line 2 Sg4    210 embryonic 1182-4H    277 embryonic GM2    160 embryonic Kc167    137 embryonic S1    206 embryonic S3    124 leg disc CME L1    205 wing disc CME-W2    140 wing disc ML-DmD8    161 wing disc ML-DmD9    240 wing disc ML-DmD16-c3    92 wing disc ML-DmD21    362 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    169 eye-antennal disc ML-DmD11    218 antennal disc ML-DmD20-c5    233 mixed discs ML-DmD4-c1    212 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    141 tumorous blood cells mbn2    121 ovary fGS/OSS    182 ovary OSC    105 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (320) Schneider line 2 Sg4  (210) embryonic 1182-4H  (277) embryonic GM2  (160) embryonic Kc167  (137) embryonic S1  (206) embryonic S3  (124) leg disc CME L1  (205) wing disc CME-W2  (140) wing disc ML-DmD8  (161) wing disc ML-DmD9  (240) wing disc ML-DmD16-c3  (92) wing disc ML-DmD21  (362) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (169) eye-antennal disc ML-DmD11  (218) antennal disc ML-DmD20-c5  (233) mixed discs ML-DmD4-c1  (212) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2  (141) tumorous blood cells mbn2  (121) ovary fGS/OSS  (182) ovary OSC  (105) ovary OSS  (68) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (320) Schneider line 2 Sg4  (210) embryonic 1182-4H  (277) embryonic GM2  (160) embryonic Kc167  137 embryonic S1  (206) embryonic S3  124 leg disc CME L1  (205) wing disc CME-W2  140 wing disc ML-DmD8  (161) wing disc ML-DmD9  (240) wing disc ML-DmD16-c3    92 wing disc ML-DmD21  (362) wing disc ML-DmD32  (188) haltere disc ML-DmD17-c3  (169) eye-antennal disc ML-DmD11  (218) antennal disc ML-DmD20-c5  (233) mixed discs ML-DmD4-c1  (212) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2  141 tumorous blood cells mbn2  121 ovary fGS/OSS  (182) ovary OSC  105 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    320 Schneider line 2 Sg4    210 embryonic 1182-4H    277 embryonic GM2    160 embryonic Kc167    137 embryonic S1    206 embryonic S3    124 leg disc CME L1    205 wing disc CME-W2    140 wing disc ML-DmD8    161 wing disc ML-DmD9    240 wing disc ML-DmD16-c3    92 wing disc ML-DmD21    362 wing disc ML-DmD32    188 haltere disc ML-DmD17-c3    169 eye-antennal disc ML-DmD11    218 antennal disc ML-DmD20-c5    233 mixed discs ML-DmD4-c1    212 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    141 tumorous blood cells mbn2    121 ovary fGS/OSS    182 ovary OSC    105 ovary OSS    68 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    77 heat shock, 4-day adult    139 Cadmium 50 mM 6 hrs, larvae L3    124 Cadmium 50 mM 12 hrs, larvae L3    124 Cadmium 50 mM 48 hrs, 4-day adult    112 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    83 Copper 15 mM 48 hrs, 4-day adult    103 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    102 Ethanol 2.5% 3 hrs, larvae L3    173 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    108 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    147 Caffeine 25 mg/ml 48 hrs, 4-day adult    80 Paraquat 5 mM 48 hrs, 4-day adult    150 Paraquat 10 mM 48 hrs, 4-day adult    187 Rotenone 2 μg 12 hrs, larvae L3    140 Rotenone 8 μg 12 hrs, larvae L3    142 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (105) cold shock, 4-day adult  (77) heat shock, 4-day adult  (139) Cadmium 50 mM 6 hrs, larvae L3  (124) Cadmium 50 mM 12 hrs, larvae L3  (124) Cadmium 50 mM 48 hrs, 4-day adult  (112) Cadmium 100 mM 48 hrs, 4-day adult  (140) Copper 0.5 mM 12 hrs, larvae L3  (83) Copper 15 mM 48 hrs, 4-day adult  (103) Zinc 5 mM 12 hrs, larvae L3  (83) Zinc 4.5 mM 48 hrs, 4-day adult  (102) Ethanol 2.5% 3 hrs, larvae L3  (173) Ethanol 5% 3 hrs, larvae L3  (121) Ethanol 10% 3 hrs, larvae L3  (134) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (108) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (147) Caffeine 25 mg/ml 48 hrs, 4-day adult  (80) Paraquat 5 mM 48 hrs, 4-day adult  (150) Paraquat 10 mM 48 hrs, 4-day adult  (187) Rotenone 2 μg 12 hrs, larvae L3  (140) Rotenone 8 μg 12 hrs, larvae L3  (142) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  105 cold shock, 4-day adult    77 heat shock, 4-day adult  (139) Cadmium 50 mM 6 hrs, larvae L3  (124) Cadmium 50 mM 12 hrs, larvae L3  (124) Cadmium 50 mM 48 hrs, 4-day adult  (112) Cadmium 100 mM 48 hrs, 4-day adult  (140) Copper 0.5 mM 12 hrs, larvae L3    83 Copper 15 mM 48 hrs, 4-day adult  103 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult  102 Ethanol 2.5% 3 hrs, larvae L3  (173) Ethanol 5% 3 hrs, larvae L3  (121) Ethanol 10% 3 hrs, larvae L3  (134) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (108) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (147) Caffeine 25 mg/ml 48 hrs, 4-day adult    80 Paraquat 5 mM 48 hrs, 4-day adult  (150) Paraquat 10 mM 48 hrs, 4-day adult  (187) Rotenone 2 μg 12 hrs, larvae L3  (140) Rotenone 8 μg 12 hrs, larvae L3  (142) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    77 heat shock, 4-day adult    139 Cadmium 50 mM 6 hrs, larvae L3    124 Cadmium 50 mM 12 hrs, larvae L3    124 Cadmium 50 mM 48 hrs, 4-day adult    112 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    83 Copper 15 mM 48 hrs, 4-day adult    103 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    102 Ethanol 2.5% 3 hrs, larvae L3    173 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    108 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    147 Caffeine 25 mg/ml 48 hrs, 4-day adult    80 Paraquat 5 mM 48 hrs, 4-day adult    150 Paraquat 10 mM 48 hrs, 4-day adult    187 Rotenone 2 μg 12 hrs, larvae L3    140 Rotenone 8 μg 12 hrs, larvae L3    142 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    77 heat shock, 4-day adult    139 Cadmium 50 mM 6 hrs, larvae L3    124 Cadmium 50 mM 12 hrs, larvae L3    124 Cadmium 50 mM 48 hrs, 4-day adult    112 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    83 Copper 15 mM 48 hrs, 4-day adult    103 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    102 Ethanol 2.5% 3 hrs, larvae L3    173 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    108 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    147 Caffeine 25 mg/ml 48 hrs, 4-day adult    80 Paraquat 5 mM 48 hrs, 4-day adult    150 Paraquat 10 mM 48 hrs, 4-day adult    187 Rotenone 2 μg 12 hrs, larvae L3    140 Rotenone 8 μg 12 hrs, larvae L3    142 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (105) cold shock, 4-day adult  (77) heat shock, 4-day adult  (139) Cadmium 50 mM 6 hrs, larvae L3  (124) Cadmium 50 mM 12 hrs, larvae L3  (124) Cadmium 50 mM 48 hrs, 4-day adult  (112) Cadmium 100 mM 48 hrs, 4-day adult  (140) Copper 0.5 mM 12 hrs, larvae L3  (83) Copper 15 mM 48 hrs, 4-day adult  (103) Zinc 5 mM 12 hrs, larvae L3  (83) Zinc 4.5 mM 48 hrs, 4-day adult  (102) Ethanol 2.5% 3 hrs, larvae L3  (173) Ethanol 5% 3 hrs, larvae L3  (121) Ethanol 10% 3 hrs, larvae L3  (134) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (108) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (147) Caffeine 25 mg/ml 48 hrs, 4-day adult  (80) Paraquat 5 mM 48 hrs, 4-day adult  (150) Paraquat 10 mM 48 hrs, 4-day adult  (187) Rotenone 2 μg 12 hrs, larvae L3  (140) Rotenone 8 μg 12 hrs, larvae L3  (142) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  105 cold shock, 4-day adult    77 heat shock, 4-day adult  139 Cadmium 50 mM 6 hrs, larvae L3  124 Cadmium 50 mM 12 hrs, larvae L3  124 Cadmium 50 mM 48 hrs, 4-day adult  112 Cadmium 100 mM 48 hrs, 4-day adult  140 Copper 0.5 mM 12 hrs, larvae L3    83 Copper 15 mM 48 hrs, 4-day adult  103 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult  102 Ethanol 2.5% 3 hrs, larvae L3  (173) Ethanol 5% 3 hrs, larvae L3  121 Ethanol 10% 3 hrs, larvae L3  134 Caffeine 1.5 mg/ml 4 hrs, larvae L3  108 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (147) Caffeine 25 mg/ml 48 hrs, 4-day adult    80 Paraquat 5 mM 48 hrs, 4-day adult  (150) Paraquat 10 mM 48 hrs, 4-day adult  (187) Rotenone 2 μg 12 hrs, larvae L3  140 Rotenone 8 μg 12 hrs, larvae L3  142 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    77 heat shock, 4-day adult    139 Cadmium 50 mM 6 hrs, larvae L3    124 Cadmium 50 mM 12 hrs, larvae L3    124 Cadmium 50 mM 48 hrs, 4-day adult    112 Cadmium 100 mM 48 hrs, 4-day adult    140 Copper 0.5 mM 12 hrs, larvae L3    83 Copper 15 mM 48 hrs, 4-day adult    103 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    102 Ethanol 2.5% 3 hrs, larvae L3    173 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    134 Caffeine 1.5 mg/ml 4 hrs, larvae L3    108 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    147 Caffeine 25 mg/ml 48 hrs, 4-day adult    80 Paraquat 5 mM 48 hrs, 4-day adult    150 Paraquat 10 mM 48 hrs, 4-day adult    187 Rotenone 2 μg 12 hrs, larvae L3    140 Rotenone 8 μg 12 hrs, larvae L3    142 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_03 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • GM14618 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0022023 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9124-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal eIF-3p40GD14127 lethal, with Scer\GAL4pnr-MD237 eIF-3p40GD14127 lethal | pupal stage, with Scer\GAL4dpp.PU eIF-3p40KK102344 eIF-3p40NIG.9124R lethal | pupal stage, with Scer\GAL4pnr-MD237 eIF-3p40GD14127 lethal | recessive eIF-3p40k09003 eIF-3p40k09306 eIF-3p40k16615 Other Phenotypes Allele neuroanatomy defective | larval stage eIF-3p40GD14127 visible, with Scer\GAL4bbg-C96 eIF-3p40KK102344 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage eIF-3p40GD14127 ganglion mother cell | larval stage eIF-3p40GD14127 wing, with Scer\GAL4bbg-C96 eIF-3p40KK102344 wing margin bristle, with Scer\GAL4bbg-C96 eIF-3p40KK102344
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of eIF-3p40 Class Mutagen Stocks Known lesion eIF-3p40k09003 P-element activity 2 -- eIF-3p40k09306 P-element activity 1 -- eIF-3p40k16615 P-element activity 1 -- eIF-3p40NP0834 1 -- eIF-3p40NP5205 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of eIF-3p40 Class Mutagen Stocks Known lesion eIF-3p40GD14127 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes eIF-3p40KK102344 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eIF-3p40NIG.9124R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(2L)cl-h3 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2L)tkv2 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Disrupted in	Df(2L)BSC51 (Deal and Cook, 2004.5.27) Df(2L)BSC110 (Deal and Cook, 2005.6.1) Df(2L)Exel7022 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14127} NA P{KK102344} NA P{NIG.9124R} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}eIF-3p40k09003 No P{lacW}eIF-3p40k09306 No P{lacW}eIF-3p40k16615 No P{lacW}l(2)SH0732SH0732 No insertion of enhancer trap binary system P{GawB}eIF-3p40NP0834 No P{GawB}eIF-3p40NP5205 No
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011) positive regulation of Notch signaling pathway inferred from mutant phenotype (Zhang et al., 2012)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
translation initiation factor activity inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with UniProtKB:O15372 (FlyBase, 1992-)
Biological Process
CV term Evidence References
translational initiation inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with UniProtKB:O15372 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytosol inferred from sequence or structural similarity (Lasko, 2000) eukaryotic translation initiation factor 3 complex inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with UniProtKB:O15372 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
eIF-3p40 - CG10306 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - CG5642 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - CG8636 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - CG9769 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - Int6 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - Tango7 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - eIF3-S10 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - eIF3-S8 experimental knowledge based (Guruharsha et al., 2011) eIF-3p40 - eIF3-S9 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions eIF-3p40 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 69808 DroID - A comprehensive database of gene and protein interactions. • FBgn0022023 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45682
Orthologs
OrthoDB Orthologs (40) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6FXRTJ Dipteran inclusive ortholog search EOG6Z62X8 Insect inclusive ortholog search EOG6RFJP6 Arthropod inclusive ortholog search EOG6J6Q6G Metazoa inclusive ortholog search EOG66DZX6
Orthologs in Drosophila Species (EOG6FXRTJ)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\eIF-3p40     Drosophila simulans   Dsim\GD14929 Y   Drosophila sechellia   Dsec\GM18040 Y   Drosophila erecta   Dere\GG24322 Y   Drosophila yakuba   Dyak\GE18701 Y   Drosophila ananassae   Dana\GF14158 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA28878 Y   Drosophila persimilis   Dper\GL26477 Y   Drosophila willistoni   Dwil\GK24148 Y   Drosophila virilis   Dvir\GJ10133 Y   Drosophila mojavensis   Dmoj\GI15660 Y   Drosophila grimshawi   Dgri\GH10269 Y
Orthologs in non-Drosophila Dipterans (EOG6Z62X8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL007945   Anopheles gambiae Malaria mosquito  Agam\AGAP009204   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ802366
Orthologs in non-Dipteran Insects (EOG6RFJP6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46247   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG004157   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11570   Atta cephalotes Leafcutter ant  Acep\ACEP13143   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17261   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20509   Linepithema humile Argentine ant  Lhum\LH25061   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21598   Solenopsis invicta Red fire ant  Sinv\SINV24012   Acyrthosiphon pisum Pea aphid  Apim\ACYPI009633   Bombyx mori Silkmoth  Bmor\BGIBMGA006141   Pediculus humanus Human body louse  Phum\PHUM509090   Tribolium castaneum Red flour beetle  Tcas\TC014327
Orthologs in non-Insect Arthropods (EOG6J6Q6G)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_305161   Ixodes scapularis Deer tick  Isca\ISCW018927
Orthologs in non-Arthropod Metazoa (EOG66DZX6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\eif-3.H   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_023965gn   Danio rerio Zebrafish  Drer\ENSDARG00000036116   Danio rerio Zebrafish  Drer\eif3ha   Xenopus tropicalis Western clawed frog  Xtro\eif3h   Gallus gallus Domestic chicken  Ggal\EIF3H   Mus musculus House mouse  Mmus\Eif3h   Rattus norvegicus Norway rat  Rnor\Eif3h   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000040153   Homo sapiens Human  Hsap\EIF3S3
Human Orthologs (1)
Gene OMIM HGNC Hsap\EIF3S3
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD14929 Drosophila sechellia Dsec\GM18040 Drosophila erecta Dere\GG24322 Drosophila yakuba Dyak\GE18701 Drosophila ananassae Dana\GF14158 Drosophila pseudoobscura pseudoobscura Dpse\GA28878 Drosophila persimilis Dper\GL26477 Drosophila willistoni Dwil\GK24148 Drosophila virilis Dvir\GJ10133 Drosophila mojavensis Dmoj\GI15660 Drosophila grimshawi Dgri\GH10269
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	10845 y1 w67c23; P{lacW}eIF-3p40k09003/CyO
Kyoto	112356 w*; P{GawB}eIF-3p40NP0834 / CyO 102701 y1 w67c23 ; P{lacW}eIF-3p40k09306 / CyO 103021 y1 w67c23 ; P{lacW}eIF-3p40k16615 / CyO 104898 y* w*; P{GawB}eIF-3p40NP5205 / CyO, P{UAS-lacZ.UW14}UW14 111254 yd2 w1118 P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{lacW}eIF-3p40k09003 P{neoFRT}40A/CyO y+
VDRC	v106189 P{KK102344}VIE-260B v36086 w1118; P{GD14127}v36086 v36087 w1118; P{GD14127}v36087
Genomic Clones ( 1 )
	BACR13M11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 92 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM14618 LD05882
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01959 AT07669 AT13816 AT18474 AT24379 GH06760 GH07024 GH09596 GH11952 GH12360 GH12936 GH12944 GH18026 GH20539 GH26285 GM04060 GM07963 GM20248 GM24389 GM27109 GM29538 GM31503 LD05962 LD06390 LD10460 LD14434 LD19932 LD21605 LD37270 LD37525 LD39318 LP16158 RE15223 RE21741 RE25185 RE32523 RE33278 RE36171 RE54433 RH18647 RH20059 RH21009 RH23831 RH24431 RH27203 RH27592 RH34010 RH35447 RH37741 RH37969 RH46127 RH55996 RH62205 RH66447 RH71416 RH71817 SD06772 SD11077 UT01025 UT01628 UT01808
Other clones	Dmel_dig_006852_0630_0526 EC27186 EK020914 EK045851 EK056458 EK107215 EK135510 EK142110 EK201102 EK206702 EK213852 EK235921 EK239539 EK247131 EK272656 EN11151 EN12949 EN15506 EN16252 EN16454 FGC023B03 FGM208D06 FGM237A01 FGM310F10 FGM322B10 LD39333 RE01806 RE01863 UT01567
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0022023 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45682
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: BcDNA:GM14618 CG9124 (Kodira, 1999.11)
Source for database merge of	Source for merge of: eIF-3p40 BcDNA:GM14618 (Misra, 2000.8.9)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_080095 NM_205909 RefSeq (Proteins) • NP_524834 NP_995631 DDBJ / EMBL / GenBank • AA246922 AA821117 AAD46836 AAF52210 AAS64639 AF160896 AQ025877 AW941397 Entrez Gene - A searchable database of RefSeq genes. • 45682 UniProtKB/Swiss-Prot • Q9U9Q4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • JAB1/Mov34/MPN/PAD-1 (IPR000555) Eukaryotic translation initiation factor 3 subunit H (IPR027524) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GM14618
Linkouts
	BioGRID - A database of protein and genetic interactions • 69808 DroID - A comprehensive database of gene and protein interactions. • FBgn0022023 DRSC - Results from RNAi screens. • FBgn0022023 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0022023 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9124-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0022023 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45682 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45682 modMine - Data generated by the modENCODE project. • FBgn0022023
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	BcDNA:GM14618   CG9124 (Lasko, 2000, Whitfield, 2000.5.17, Zhang et al., 2012, Keleman et al., 2009.8.5, Zhang et al., 2012, Cammarato et al., 2011, Puri et al., 2008) eIF-3 (Spradling et al., 1999) eIF3h (Lee et al., 2010) eIF-3p40 (Lee et al., 2010, Zhang et al., 2012, Puri et al., 2008, Japanese National Institute of Genetics, 2012.5.21) eIf3-p44 (Jasper et al., 2002) eIF3-S3 (Lasko, 2000) l(2)k09003 (Beaton, 2000.1.31, BDGP Project Members, 1994-1999, )
Name Synonym	Eukaryotic initiation factor 3 p40 subunit (Spradling et al., 1999, Cammarato et al., 2011)
Secondary FlyBase IDs
	FBgn0027910
References ( 36 )
Generate a list of	All references relating to this gene ( 36 )
List References by type	Research paper  ( 8 ) Supplementary material  ( 9 ) Personal communication to FlyBase  ( 11 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) Curated genome annotation  ( 3 ) Website  ( 1 )
Recent research papers ( 1 )
	Zhang et al., 2012, G3 (Bethesda) 2(12): 1563--1575 A Targeted In Vivo RNAi Screen Reveals Deubiquitinases as New Regulators of Notch Signaling. [FBrf0220374] Show all research papers ...