Gene Dmel\ubl

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General Information

Symbol

Dmel\ubl

Species

D. melanogaster

Name

ubiquitin like

Annotation symbol

CG3450

Feature type

protein_coding_gene

FlyBase ID

FBgn0022224

Gene Model Status

Current

Stock availability

4 publicly available

Also Known As

mut182, l(2)k03203

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

42D4-42D4

Sequence location

2R:2,697,516..2,698,035 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

The gene ubiquitin like is referred to in FlyBase by the symbol Dmel\ubl (CG3450, FBgn0022224). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: neurogenesis. 3 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Ubiquitin supergroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval trachea, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1628637_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of ubl. Gene sequence location is 2R:2697516..2698035.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

42D4-42D4

Limits computationally determined from genome sequence between P{lacW}geminin^k14019&P{PZ}Adf1⁰¹³⁴⁹ and P{lacW}ubl^k03203&P{PZ}CG3287⁰⁹⁹⁶⁷

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

42D1-42D3

(determined by in situ hybridisation)

(Spradling et al., 1999)

42D1-42D3

(BDGP Project Members, 1994-1999)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\ubl for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.48

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

ubl-RA

FBtr0086211

NM_136395

396

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

ubl-PA

FBpp0085529

8.6

8.70

NP_610239

AAF57398

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Ubiquitin supergroup (IPR019955)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9V998

UniProtKB/TrEMBL

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval trachea, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult testis, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		582.825
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		542.625
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		650.6
Adult Carcass		203.2
Expression Level Scale		None Low Moderate High

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(582.825)
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		(542.625)
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		(650.6)
Adult Carcass		203.2
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		582.825
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		542.625
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		650.6
Adult Carcass		203.2
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		582.825
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		542.625
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		650.6
Adult Carcass		203.2
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		582.825
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		542.625
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		650.6
Adult Carcass		203.2
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		582.825
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		542.625
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		650.6
Adult Carcass		203.2
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		582.825
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		542.625
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		650.6
Adult Carcass		203.2
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		582.825
Larval Midgut		213.4
Larval Hindgut		297.1
Larval Malpighian Tubules		330
Larval Fat Body		345.7
Larval Salivary Gland		447.8
Larval Trachea		542.625
Larval Carcass		354.9
Adult Head		277
Adult Eye		399
Adult Brain		216.9
Adult Thoracic-Abdominal Ganglion		198
Adult Crop		310.1
Adult Midgut		235
Adult Hindgut		224.3
Adult Malpighian Tubules		205.2
Adult Fat Body		350.8
Adult Salivary Gland		320.2
Adult Heart		366.025
Adult VirginFemale Spermatheca		250.4
Adult InseminatedFemale Spermatheca		266.6
Adult Ovary		397.1
Adult Testis		150.1
Adult Male Accessory Gland		650.6
Adult Carcass		203.2
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	277
NA	Eye	399
NA	Brain	216.9
582.825	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	198
NA	Crop	310.1
213.4	Midgut	235
297.1	Hindgut	224.3
330	Malpighian Tubules	205.2
345.7	Fat Body	350.8
447.8	Salivary Gland	320.2
NA	Heart	366.025
542.625	Trachea	NA
NA	VirginFemale Spermatheca	250.4
NA	InseminatedFemale Spermatheca	266.6
NA	Ovary	397.1
NA	Testis	150.1
NA	Male Accessory Gland	650.6
354.9	Carcass	203.2

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		40
central nervous system, larvae L3		42
central nervous system, pupae P8		38
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		42
digestive system, 1-day adult		25
digestive system, 4-day adult		28
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		45
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		46
accessory gland, mated 4-day male		46
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(40)
central nervous system, larvae L3		(42)
central nervous system, pupae P8		(38)
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		(41)
digestive system, larvae L3 wandering		(42)
digestive system, 1-day adult		25
digestive system, 4-day adult		(28)
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		(45)
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		(47)
ovary, mated 4-day female		(43)
testis, mated 4-day male		(46)
accessory gland, mated 4-day male		(46)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		40
central nervous system, larvae L3		42
central nervous system, pupae P8		38
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		42
digestive system, 1-day adult		25
digestive system, 4-day adult		28
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		45
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		46
accessory gland, mated 4-day male		46
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		40
central nervous system, larvae L3		42
central nervous system, pupae P8		38
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		42
digestive system, 1-day adult		25
digestive system, 4-day adult		28
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		45
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		46
accessory gland, mated 4-day male		46
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		40
central nervous system, larvae L3		42
central nervous system, pupae P8		38
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		42
digestive system, 1-day adult		25
digestive system, 4-day adult		28
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		45
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		46
accessory gland, mated 4-day male		46
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(40)
central nervous system, larvae L3		(42)
central nervous system, pupae P8		(38)
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		(41)
digestive system, larvae L3 wandering		(42)
digestive system, 1-day adult		25
digestive system, 4-day adult		28
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		(45)
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		(47)
ovary, mated 4-day female		(43)
testis, mated 4-day male		(46)
accessory gland, mated 4-day male		(46)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		40
central nervous system, larvae L3		42
central nervous system, pupae P8		38
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		42
digestive system, 1-day adult		25
digestive system, 4-day adult		28
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		45
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		46
accessory gland, mated 4-day male		46
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		40
central nervous system, larvae L3		42
central nervous system, pupae P8		38
head, virgin 1-day female		16
head, virgin 4-day female		17
head, virgin 20-day female		10
head, mated 1-day female		14
head, mated 4-day female		17
head, mated 20-day female		11
head, mated 1-day male		18
head, mated 4-day male		21
head, mated 20-day male		25
salivary gland, larvae L3 wandering		24
salivary gland, white prepupae		41
digestive system, larvae L3 wandering		42
digestive system, 1-day adult		25
digestive system, 4-day adult		28
digestive system, 20-day adult		16
fat body, larvae L3 wandering		9
fat body, white prepupae		24
fat body, pupae P8		17
carcass, larvae L3 wandering		45
carcass, 1-day adult		18
carcass, 4-day adult		21
carcass, 20-day adult		16
ovary, virgin 4-day female		47
ovary, mated 4-day female		43
testis, mated 4-day male		46
accessory gland, mated 4-day male		46
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		76
embryo 04-06hr		96
embryo 06-08hr		75
embryo 08-10hr		81
embryo 10-12hr		77
embryo 12-14hr		57
embryo 14-16hr		24
embryo 16-18hr		31
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		28
larva L1		26
larva L2		35
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		29
larva L3 puffstage 7-9		31
white prepupae new		39
white prepupae 12hr		36
white prepupae 24hr		44
pupae 2d postWPP		36
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		39
adult female 30day		36
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(39)
embryo 02-04hr		(76)
embryo 04-06hr		(96)
embryo 06-08hr		(75)
embryo 08-10hr		(81)
embryo 10-12hr		(77)
embryo 12-14hr		(57)
embryo 14-16hr		24
embryo 16-18hr		(31)
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		(28)
larva L1		26
larva L2		(35)
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		(29)
larva L3 puffstage 7-9		(31)
white prepupae new		(39)
white prepupae 12hr		(36)
white prepupae 24hr		(44)
pupae 2d postWPP		(36)
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		(39)
adult female 30day		(36)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		76
embryo 04-06hr		96
embryo 06-08hr		75
embryo 08-10hr		81
embryo 10-12hr		77
embryo 12-14hr		57
embryo 14-16hr		24
embryo 16-18hr		31
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		28
larva L1		26
larva L2		35
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		29
larva L3 puffstage 7-9		31
white prepupae new		39
white prepupae 12hr		36
white prepupae 24hr		44
pupae 2d postWPP		36
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		39
adult female 30day		36
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		76
embryo 04-06hr		96
embryo 06-08hr		75
embryo 08-10hr		81
embryo 10-12hr		77
embryo 12-14hr		57
embryo 14-16hr		24
embryo 16-18hr		31
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		28
larva L1		26
larva L2		35
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		29
larva L3 puffstage 7-9		31
white prepupae new		39
white prepupae 12hr		36
white prepupae 24hr		44
pupae 2d postWPP		36
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		39
adult female 30day		36
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		76
embryo 04-06hr		96
embryo 06-08hr		75
embryo 08-10hr		81
embryo 10-12hr		77
embryo 12-14hr		57
embryo 14-16hr		24
embryo 16-18hr		31
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		28
larva L1		26
larva L2		35
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		29
larva L3 puffstage 7-9		31
white prepupae new		39
white prepupae 12hr		36
white prepupae 24hr		44
pupae 2d postWPP		36
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		39
adult female 30day		36
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(39)
embryo 02-04hr		(76)
embryo 04-06hr		(96)
embryo 06-08hr		(75)
embryo 08-10hr		(81)
embryo 10-12hr		(77)
embryo 12-14hr		(57)
embryo 14-16hr		24
embryo 16-18hr		31
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		28
larva L1		26
larva L2		(35)
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		29
larva L3 puffstage 7-9		31
white prepupae new		(39)
white prepupae 12hr		(36)
white prepupae 24hr		(44)
pupae 2d postWPP		(36)
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		(39)
adult female 30day		(36)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		76
embryo 04-06hr		96
embryo 06-08hr		75
embryo 08-10hr		81
embryo 10-12hr		77
embryo 12-14hr		57
embryo 14-16hr		24
embryo 16-18hr		31
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		28
larva L1		26
larva L2		35
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		29
larva L3 puffstage 7-9		31
white prepupae new		39
white prepupae 12hr		36
white prepupae 24hr		44
pupae 2d postWPP		36
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		39
adult female 30day		36
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		39
embryo 02-04hr		76
embryo 04-06hr		96
embryo 06-08hr		75
embryo 08-10hr		81
embryo 10-12hr		77
embryo 12-14hr		57
embryo 14-16hr		24
embryo 16-18hr		31
embryo 18-20hr		19
embryo 20-22hr		22
embryo 22-24hr		28
larva L1		26
larva L2		35
larva L3 12hr old		25
larva L3 puffstage 1-2		26
larva L3 puffstage 3-6		29
larva L3 puffstage 7-9		31
white prepupae new		39
white prepupae 12hr		36
white prepupae 24hr		44
pupae 2d postWPP		36
pupae 3d postWPP		25
pupae 4d postWPP		12
adult male 01day		20
adult male 05day		17
adult male 30day		15
adult female 01day		22
adult female 05day		39
adult female 30day		36
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		99
Schneider line 2 Sg4		88
embryonic 1182-4H		39
embryonic GM2		52
embryonic Kc167		77
embryonic S1		86
embryonic S3		81
leg disc CME L1		82
wing disc CME-W2		118
wing disc ML-DmD8		58
wing disc ML-DmD9		57
wing disc ML-DmD16-c3		69
wing disc ML-DmD21		105
wing disc ML-DmD32		44
haltere disc ML-DmD17-c3		68
eye-antennal disc ML-DmD11		62
antennal disc ML-DmD20-c5		81
mixed discs ML-DmD4-c1		92
CNS ML-DmBG1-c1		84
CNS ML-DmBG2-c2		91
tumorous blood cells mbn2		48
ovary fGS/OSS		38
ovary OSC		48
ovary OSS		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(99)
Schneider line 2 Sg4		(88)
embryonic 1182-4H		(39)
embryonic GM2		(52)
embryonic Kc167		(77)
embryonic S1		(86)
embryonic S3		(81)
leg disc CME L1		(82)
wing disc CME-W2		(118)
wing disc ML-DmD8		(58)
wing disc ML-DmD9		(57)
wing disc ML-DmD16-c3		(69)
wing disc ML-DmD21		(105)
wing disc ML-DmD32		(44)
haltere disc ML-DmD17-c3		(68)
eye-antennal disc ML-DmD11		(62)
antennal disc ML-DmD20-c5		(81)
mixed discs ML-DmD4-c1		(92)
CNS ML-DmBG1-c1		(84)
CNS ML-DmBG2-c2		(91)
tumorous blood cells mbn2		(48)
ovary fGS/OSS		(38)
ovary OSC		(48)
ovary OSS		25
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		99
Schneider line 2 Sg4		88
embryonic 1182-4H		39
embryonic GM2		52
embryonic Kc167		77
embryonic S1		86
embryonic S3		81
leg disc CME L1		82
wing disc CME-W2		(118)
wing disc ML-DmD8		58
wing disc ML-DmD9		57
wing disc ML-DmD16-c3		69
wing disc ML-DmD21		105
wing disc ML-DmD32		44
haltere disc ML-DmD17-c3		68
eye-antennal disc ML-DmD11		62
antennal disc ML-DmD20-c5		81
mixed discs ML-DmD4-c1		92
CNS ML-DmBG1-c1		84
CNS ML-DmBG2-c2		91
tumorous blood cells mbn2		48
ovary fGS/OSS		38
ovary OSC		48
ovary OSS		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		99
Schneider line 2 Sg4		88
embryonic 1182-4H		39
embryonic GM2		52
embryonic Kc167		77
embryonic S1		86
embryonic S3		81
leg disc CME L1		82
wing disc CME-W2		118
wing disc ML-DmD8		58
wing disc ML-DmD9		57
wing disc ML-DmD16-c3		69
wing disc ML-DmD21		105
wing disc ML-DmD32		44
haltere disc ML-DmD17-c3		68
eye-antennal disc ML-DmD11		62
antennal disc ML-DmD20-c5		81
mixed discs ML-DmD4-c1		92
CNS ML-DmBG1-c1		84
CNS ML-DmBG2-c2		91
tumorous blood cells mbn2		48
ovary fGS/OSS		38
ovary OSC		48
ovary OSS		25
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		99
Schneider line 2 Sg4		88
embryonic 1182-4H		39
embryonic GM2		52
embryonic Kc167		77
embryonic S1		86
embryonic S3		81
leg disc CME L1		82
wing disc CME-W2		118
wing disc ML-DmD8		58
wing disc ML-DmD9		57
wing disc ML-DmD16-c3		69
wing disc ML-DmD21		105
wing disc ML-DmD32		44
haltere disc ML-DmD17-c3		68
eye-antennal disc ML-DmD11		62
antennal disc ML-DmD20-c5		81
mixed discs ML-DmD4-c1		92
CNS ML-DmBG1-c1		84
CNS ML-DmBG2-c2		91
tumorous blood cells mbn2		48
ovary fGS/OSS		38
ovary OSC		48
ovary OSS		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(99)
Schneider line 2 Sg4		(88)
embryonic 1182-4H		(39)
embryonic GM2		(52)
embryonic Kc167		(77)
embryonic S1		(86)
embryonic S3		(81)
leg disc CME L1		(82)
wing disc CME-W2		(118)
wing disc ML-DmD8		(58)
wing disc ML-DmD9		(57)
wing disc ML-DmD16-c3		(69)
wing disc ML-DmD21		(105)
wing disc ML-DmD32		(44)
haltere disc ML-DmD17-c3		(68)
eye-antennal disc ML-DmD11		(62)
antennal disc ML-DmD20-c5		(81)
mixed discs ML-DmD4-c1		(92)
CNS ML-DmBG1-c1		(84)
CNS ML-DmBG2-c2		(91)
tumorous blood cells mbn2		(48)
ovary fGS/OSS		(38)
ovary OSC		(48)
ovary OSS		25
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		99
Schneider line 2 Sg4		88
embryonic 1182-4H		39
embryonic GM2		52
embryonic Kc167		77
embryonic S1		86
embryonic S3		81
leg disc CME L1		82
wing disc CME-W2		118
wing disc ML-DmD8		58
wing disc ML-DmD9		57
wing disc ML-DmD16-c3		69
wing disc ML-DmD21		105
wing disc ML-DmD32		44
haltere disc ML-DmD17-c3		68
eye-antennal disc ML-DmD11		62
antennal disc ML-DmD20-c5		81
mixed discs ML-DmD4-c1		92
CNS ML-DmBG1-c1		84
CNS ML-DmBG2-c2		91
tumorous blood cells mbn2		48
ovary fGS/OSS		38
ovary OSC		48
ovary OSS		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		99
Schneider line 2 Sg4		88
embryonic 1182-4H		39
embryonic GM2		52
embryonic Kc167		77
embryonic S1		86
embryonic S3		81
leg disc CME L1		82
wing disc CME-W2		118
wing disc ML-DmD8		58
wing disc ML-DmD9		57
wing disc ML-DmD16-c3		69
wing disc ML-DmD21		105
wing disc ML-DmD32		44
haltere disc ML-DmD17-c3		68
eye-antennal disc ML-DmD11		62
antennal disc ML-DmD20-c5		81
mixed discs ML-DmD4-c1		92
CNS ML-DmBG1-c1		84
CNS ML-DmBG2-c2		91
tumorous blood cells mbn2		48
ovary fGS/OSS		38
ovary OSC		48
ovary OSS		25
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		36
Cadmium 50 mM 6 hrs, larvae L3		48
Cadmium 50 mM 12 hrs, larvae L3		52
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		40
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		35
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		38
Ethanol 5% 3 hrs, larvae L3		38
Ethanol 10% 3 hrs, larvae L3		35
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		44
Paraquat 10 mM 48 hrs, 4-day adult		30
Rotenone 2 μg 12 hrs, larvae L3		33
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		(36)
Cadmium 50 mM 6 hrs, larvae L3		(48)
Cadmium 50 mM 12 hrs, larvae L3		(52)
Cadmium 50 mM 48 hrs, 4-day adult		(32)
Cadmium 100 mM 48 hrs, 4-day adult		(40)
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		(35)
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		(38)
Ethanol 5% 3 hrs, larvae L3		(38)
Ethanol 10% 3 hrs, larvae L3		(35)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		(44)
Paraquat 10 mM 48 hrs, 4-day adult		(30)
Rotenone 2 μg 12 hrs, larvae L3		(33)
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		36
Cadmium 50 mM 6 hrs, larvae L3		48
Cadmium 50 mM 12 hrs, larvae L3		52
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		40
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		35
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		38
Ethanol 5% 3 hrs, larvae L3		38
Ethanol 10% 3 hrs, larvae L3		35
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		44
Paraquat 10 mM 48 hrs, 4-day adult		30
Rotenone 2 μg 12 hrs, larvae L3		33
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		36
Cadmium 50 mM 6 hrs, larvae L3		48
Cadmium 50 mM 12 hrs, larvae L3		52
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		40
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		35
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		38
Ethanol 5% 3 hrs, larvae L3		38
Ethanol 10% 3 hrs, larvae L3		35
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		44
Paraquat 10 mM 48 hrs, 4-day adult		30
Rotenone 2 μg 12 hrs, larvae L3		33
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		36
Cadmium 50 mM 6 hrs, larvae L3		48
Cadmium 50 mM 12 hrs, larvae L3		52
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		40
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		35
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		38
Ethanol 5% 3 hrs, larvae L3		38
Ethanol 10% 3 hrs, larvae L3		35
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		44
Paraquat 10 mM 48 hrs, 4-day adult		30
Rotenone 2 μg 12 hrs, larvae L3		33
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		(36)
Cadmium 50 mM 6 hrs, larvae L3		(48)
Cadmium 50 mM 12 hrs, larvae L3		(52)
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		(40)
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		(35)
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		(38)
Ethanol 5% 3 hrs, larvae L3		(38)
Ethanol 10% 3 hrs, larvae L3		(35)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		(44)
Paraquat 10 mM 48 hrs, 4-day adult		30
Rotenone 2 μg 12 hrs, larvae L3		(33)
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		36
Cadmium 50 mM 6 hrs, larvae L3		48
Cadmium 50 mM 12 hrs, larvae L3		52
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		40
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		35
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		38
Ethanol 5% 3 hrs, larvae L3		38
Ethanol 10% 3 hrs, larvae L3		35
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		44
Paraquat 10 mM 48 hrs, 4-day adult		30
Rotenone 2 μg 12 hrs, larvae L3		33
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		17
cold shock, 4-day adult		6
heat shock, 4-day adult		36
Cadmium 50 mM 6 hrs, larvae L3		48
Cadmium 50 mM 12 hrs, larvae L3		52
Cadmium 50 mM 48 hrs, 4-day adult		32
Cadmium 100 mM 48 hrs, 4-day adult		40
Copper 0.5 mM 12 hrs, larvae L3		12
Copper 15 mM 48 hrs, 4-day adult		15
Zinc 5 mM 12 hrs, larvae L3		35
Zinc 4.5 mM 48 hrs, 4-day adult		21
Ethanol 2.5% 3 hrs, larvae L3		38
Ethanol 5% 3 hrs, larvae L3		38
Ethanol 10% 3 hrs, larvae L3		35
Caffeine 1.5 mg/ml 4 hrs, larvae L3		21
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		24
Caffeine 25 mg/ml 48 hrs, 4-day adult		14
Paraquat 5 mM 48 hrs, 4-day adult		44
Paraquat 10 mM 48 hrs, 4-day adult		30
Rotenone 2 μg 12 hrs, larvae L3		33
Rotenone 8 μg 12 hrs, larvae L3		26
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0022224

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG3450-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal

ubl^GD13177

lethal | recessive

ubl^k03203

partially lethal - majority die | pupal stage, with Scer\GAL4^pnr-MD237

ubl^GD13177

Other Phenotypes

Allele

neuroanatomy defective | larval stage

ubl^GD13177

visible, with Scer\GAL4^pnr-MD237

ubl^GD13177

Phenotype manifest in

Allele

embryonic/larval neuroblast | larval stage

ubl^GD13177

ganglion mother cell | larval stage

ubl^GD13177

mesothoracic tergum, with Scer\GAL4^pnr-MD237

ubl^GD13177

trichogen cell, with Scer\GAL4^pnr-MD237

ubl^GD13177

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of ubl	Class	Mutagen	Stocks	Known lesion
ubl^k03203		P-element activity	2	Yes
ubl^GS6103			1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of ubl	Class	Mutagen	Stocks	Known lesion
ubl^GD13177		in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Disrupted in

Df(2R)42

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2R)cn88b

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2R)Exel6050

(Ryder, 2004.4.26)

Df(2R)nap2

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2R)nap16

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Not disrupted in

Df(2R)pk78s

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD13177}

Insertions

Type of insertions

Name

Expression data

insertion of enhancer trap

P{lacW}ubl^k03203

insertion of mobile activating element

P{GSV3}ubl^GS6103

Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )

There is no information supporting a molecular function term for this gene.

(Based on a review of available data before: 2006)

Terms Based on Experimental Evidence ( 1 term )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

neurogenesis

inferred from mutant phenotype

(Neumüller et al., 2011)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function ( 0 terms)

Biological Process ( 0 terms)

Cellular Component

CV term

Evidence

References

cytoplasm

inferred from sequence or structural similarity with UniProtKB:Q9BZL1

(assigned by UniProtKB)

(Swiss-Prot Project Members, 2004.10.25)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

ubl - Plod

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

ubl allele

Gene

References

unspecified

Nsf2

(Laviolette et al., 2005)

External Data

Linkouts

DPiM - DPiM, Drosophila Protein interaction Map

•

FBgn0022224

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0022224

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

35592

Orthologs

OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6XD4BZ

Dipteran inclusive ortholog search

EOG6GTKPM

Insect inclusive ortholog search

EOG641P8N

Arthropod inclusive ortholog search

EOG6NZSBG

Metazoa inclusive ortholog search

EOG6Q8HTM

Orthologs in Drosophila Species (EOG6XD4BZ)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA17459

Drosophila persimilis

Dper\GL10969

Drosophila willistoni

Dwil\GK22148

Drosophila virilis

Dvir\GJ22181

Drosophila mojavensis

Dmoj\Tes39

Drosophila grimshawi

Dgri\GH21758

Orthologs in non-Drosophila Dipterans (EOG6GTKPM)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL008458

Anopheles gambiae

Malaria mosquito

Agam\AGAP011251

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ011517

Orthologs in non-Dipteran Insects (EOG641P8N)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB49085

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG002718

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH10167

Atta cephalotes

Leafcutter ant

Acep\ACEP20712

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO15167

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL12503

Linepithema humile

Argentine ant

Lhum\LH23389

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB15572

Solenopsis invicta

Red fire ant

Sinv\SINV18080

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI006377

Pediculus humanus

Human body louse

Phum\PHUM195490

Tribolium castaneum

Red flour beetle

Tcas\TC030562

Orthologs in non-Insect Arthropods (EOG6NZSBG)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_95804

Ixodes scapularis

Deer tick

Isca\ISCW010702

Orthologs in non-Arthropod Metazoa (EOG6Q8HTM)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\ubl-5

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_023887gn

Xenopus tropicalis

Western clawed frog

Xtro\ubl5

Mus musculus

House mouse

Mmus\Ubl5

Mus musculus

House mouse

Mmus\Gm2001

Mus musculus

House mouse

Mmus\Gm6803

Mus musculus

House mouse

Mmus\Gm2001

Rattus norvegicus

Norway rat

Rnor\Ubl5

Homo sapiens

Human

Hsap\UBL5

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\UBL5

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA17459

Drosophila persimilis

Dper\GL10969

Drosophila willistoni

Dwil\GK22148

Drosophila virilis

Dvir\GJ22181

Drosophila mojavensis

Dmoj\Tes39

Drosophila grimshawi

Dgri\GH21758

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Bloomington

10528

y¹ w^67c23; P{lacW}ubl^k03203/CyO

Kyoto

200914

w^*; P{GSV3}ubl^GS6103/SM1

102264

y¹ w^67c23 ; P{lacW}ubl^k03203 / CyO

VDRC

v26871

w¹¹¹⁸; P{GD13177}v26871/CyO

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 6 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones