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Gene Dmel\Tsf1

General Information
Symbol	Dmel\Tsf1	Species	D. melanogaster
Name	Transferrin 1	Annotation symbol	CG6186
Feature type	protein_coding_gene	FlyBase ID	FBgn0022355
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	17A9-17A9	Sequence location	X:18,281,117..18,284,377 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Transferrin 1 is referred to in FlyBase by the symbol Dmel\Tsf1 (CG6186, FBgn0022355). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: iron ion transmembrane transporter activity; ferric iron binding. Based on sequence similarity, it is predicted to be involved in the biological process: cellular iron ion homeostasis. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Transferrin; Transferrin family; Transferrin family, iron binding site; Transferrin, Insecta. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval hindgut, adult heart, larval/adult fat body, larval trachea, adult spermathecae, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, adult hindgut, adult Malpighian tubules, larval/adult salivary gland, adult testis. Gene sequence location is X:18281848..18284377.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Controlled Vocabulary Terms olfactory behavior
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 17A9-17A9   Limits computationally determined from genome sequence between P{EP}EP1378 and P{EP}CG32549EP1317
Experimentally Determined Cytological Location
Cytogenetic map Notes References 17B1-17B2     (Yoshiga, 1998.4.23) 17B1-17B2   (determined by in situ hybridisation)   (Yoshiga et al., 1999) 17B1-17B2   (determined by in situ hybridisation)   (Law et al., 1997)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Tsf1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50 Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Tsf1-RA FBtr0074559  NM_078677   2017   641 Tsf1-RB FBtr0340423     2854   641
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Tsf1-PA   FBpp0074331   71.8   641   7.07     NP_523401   AAF48831 Tsf1-PB   FBpp0309369   71.8   641   7.07
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Transferrin family, iron binding site (IPR018195) Transferrin family (IPR001156) Transferrin, Insecta (IPR015560) Transferrin (IPR016357)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA567347   AA568049   AA697506   AE014298 AAF48831   AF061268 AAC67389   AF083317   AI062184   AI062762   AI062836   AI062972   AI063195   AI063196   AI063636   AI063980   AI064025   AI064100   AI064236   AI064452   AI064642   AI106686   AI106717   AI106902   AI106903   AI107089   AI107616   AI107783   AI107792   AI108759   AI108819   AI108835   AI109012   AI109289   AI109521   AI113385   AI113471   AI113957   AI114081   AI134571   AI134616   AI134759   AI135224   AI135306   AI135806   AI135836   AI135971   AI238152   AI238177   AI238436   AI238445   AI238574   AI238777   AI238967   AI257131   AI293012   AI293055   AI293184   AI293195   AI386711   AI386855   AI387052   AI387173   AI387305   AI387617   AI387694   AI387986   AI388054   AI388145   AI388162   AI388393   AI388453   AI388705   AI388742   AI388951   AI389258   AI389579   AI389600   AI402302   AI402485   AI402630   AI402757   AI402818   AI402853   AI402950   AI403552   AI403678   AI403818   AI404058   AI404231   AI404649   AI404660   AI404992   AI405273   AI405808   AI513793   AI513849   AI514091   AI514101   AI516991   AI517039   AI517726   AI946631   AY232154   BF486244   BF491482   BF493621   BF496351   BF498199   BF502728   BF502876   BF503591   BG632830   BG633071   BG633232   BG633442   BG635016   BI163836   BI564402   BI564403   BI564406   BI564407   BI564408   BI564410   BI564411   BI564413   BI564414   BI564415   BI564418   BI564419   BI564420   BI564421   BI564423   BI564424   BI565848   BI565850   BI565851   BI565853   BI565855   BI565856   BI565861   BI565862   BI565863   BI565864   BI565865   BI565867   BI565872   BI565873   BI565874   BI565878   BI565879   BI565880   BI565881   BI565883   BI565885   BI568740   BI568741   BI568742   BI568743   BI568746   BI568751   BI568752   BI568757   BI568760   BI568764   BI568765   BI568767   BI568768   BI568769   BI568774   BI568776   BI568778   BI568782   BI568786   BI568788   BI568789   BI568791   BI568794   BI568799   BI568801   BI568803   BI568804   BI568805   BI568806   BI572249   BI572865   BI572866   BI572867   BI572870   BI572872   BI572874   BI572875   BI572878   BI572879   BI572880   BI572881   BI572883   BI572884   BI572885   BI572886   BI572887   BI572888   BI572890   BI572891   BI572892   BI572895   BI572896   BI572898   BI572900   BI572902   BI572903   BI572905   BI572906   BI572907   BI572908   BI572909   BI572916   BI572918   BI572919   BI572920   BI572921   BI572923   BI572924   BI572926   BI572927   BI572928   BI572930   BI572931   BI572932   BI572933   BI572934   BI572935   BI573139   BI573662   BI576014   BI577082   BI577083   BI577084   BI577087   BI577093   BI577094   BI577097   BI577099   BI577101   BI577105   BI577108   BI577109   BI577110   BI577111   BI577112   BI577114   BI577115   BI577117   BI577119   BI577120   BI577121   BI577123   BI577124   BI577125   BI577126   BI577129   BI577131   BI577132   BI585315   BI585317   BI585318   BI585319   BI585330   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BI628114   BI628116   BI628117   BI628119   BI628121   BI628122   BI628124   BI628126   BI631999   BI632000   BI632004   BI632005   BI632007   BI632008   BI632011   BI632012   BI632014   BI632015   BI632019   BI632023   BI632025   BI632030   BI632032   BI632034   BI632037   BI632038   BI632039   BI632041   BI632043   BI632045   BI632047   BI632050   BI632052   BI632055   BI632056   BI632058   BI632061   BI632067   BI632070   BI632072   BI632073   BI632075   BI632076   BI632077   BI632078   BI632081   BI632085   BI632090   BI632097   BI632098   BI632102   BI632103   BI638004   BI638005   BI638006   BI638007   BI638008   BI638009   BI638011   BI638012   BI638014   BI638015   BI638017   BI638018   BI638019   BI638021   BI638022   BI638023   BI638024   BI638027   BT031334   CK131640   CK658600   CK659357   CO266735   CO277919   CO280978   CO285046   CO298359   CO299272   CO299955   CO306079   CO312793   CO315937   EC052520   EC054507   EC073729   EC084000   EC084536   EC085173   EC087922   EC089337   EC222015   EC237826   EC248142   EL872105   EL872106   EL872233   EL872474   EL873288   EL876515   EL876516   EL878990   EL878991   EL879062   EL879188   EL879189   EL879618   EL879619   EL880442   EL880443   EL883207   EL883208   EL883619   EL883620   EL883711   EL883712   EL883816   EV591594   EV594401   EV594913   EV599825   EV600727   GH823280
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VWV6 O97355
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
extracellular region inferred from direct assay (Karlsson et al., 2004)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, larval hindgut, adult heart, larval/adult fat body, larval trachea, adult spermathecae, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, adult hindgut, adult Malpighian tubules, larval/adult salivary gland, adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8    58 head, virgin 1-day female    437 head, virgin 4-day female    244 head, virgin 20-day female    2809 head, mated 1-day female    175 head, mated 4-day female    321 head, mated 20-day female    1386 head, mated 1-day male    304 head, mated 4-day male    525 head, mated 20-day male    1368 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    55 digestive system, 4-day adult    25 digestive system, 20-day adult    107 fat body, larvae L3 wandering    633 fat body, white prepupae    51 fat body, pupae P8    115 carcass, larvae L3 wandering    60 carcass, 1-day adult    626 carcass, 4-day adult    418 carcass, 20-day adult    1877 ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male    152 accessory gland, mated 4-day male    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8  (58) head, virgin 1-day female  (437) head, virgin 4-day female  (244) head, virgin 20-day female  (2809) head, mated 1-day female  (175) head, mated 4-day female  (321) head, mated 20-day female  (1386) head, mated 1-day male  (304) head, mated 4-day male  (525) head, mated 20-day male  (1368) salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult  (55) digestive system, 4-day adult    25 digestive system, 20-day adult  (107) fat body, larvae L3 wandering  (633) fat body, white prepupae  (51) fat body, pupae P8  (115) carcass, larvae L3 wandering  (60) carcass, 1-day adult  (626) carcass, 4-day adult  (418) carcass, 20-day adult  (1877) ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male  (152) accessory gland, mated 4-day male  (30) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8    58 head, virgin 1-day female  (437) head, virgin 4-day female  (244) head, virgin 20-day female  (2809) head, mated 1-day female  (175) head, mated 4-day female  (321) head, mated 20-day female  (1386) head, mated 1-day male  (304) head, mated 4-day male  (525) head, mated 20-day male  (1368) salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    55 digestive system, 4-day adult    25 digestive system, 20-day adult  107 fat body, larvae L3 wandering  (633) fat body, white prepupae    51 fat body, pupae P8  (115) carcass, larvae L3 wandering    60 carcass, 1-day adult  (626) carcass, 4-day adult  (418) carcass, 20-day adult  (1877) ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male  (152) accessory gland, mated 4-day male    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8    58 head, virgin 1-day female    437 head, virgin 4-day female    244 head, virgin 20-day female    2809 head, mated 1-day female    175 head, mated 4-day female    321 head, mated 20-day female    1386 head, mated 1-day male    304 head, mated 4-day male    525 head, mated 20-day male    1368 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    55 digestive system, 4-day adult    25 digestive system, 20-day adult    107 fat body, larvae L3 wandering    633 fat body, white prepupae    51 fat body, pupae P8    115 carcass, larvae L3 wandering    60 carcass, 1-day adult    626 carcass, 4-day adult    418 carcass, 20-day adult    1877 ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male    152 accessory gland, mated 4-day male    30 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8    58 head, virgin 1-day female    437 head, virgin 4-day female    244 head, virgin 20-day female    2809 head, mated 1-day female    175 head, mated 4-day female    321 head, mated 20-day female    1386 head, mated 1-day male    304 head, mated 4-day male    525 head, mated 20-day male    1368 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    55 digestive system, 4-day adult    25 digestive system, 20-day adult    107 fat body, larvae L3 wandering    633 fat body, white prepupae    51 fat body, pupae P8    115 carcass, larvae L3 wandering    60 carcass, 1-day adult    626 carcass, 4-day adult    418 carcass, 20-day adult    1877 ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male    152 accessory gland, mated 4-day male    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8  (58) head, virgin 1-day female  (437) head, virgin 4-day female  (244) head, virgin 20-day female  (2809) head, mated 1-day female  (175) head, mated 4-day female  (321) head, mated 20-day female  (1386) head, mated 1-day male  (304) head, mated 4-day male  (525) head, mated 20-day male  (1368) salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult  (55) digestive system, 4-day adult    25 digestive system, 20-day adult  (107) fat body, larvae L3 wandering  (633) fat body, white prepupae  (51) fat body, pupae P8  (115) carcass, larvae L3 wandering  (60) carcass, 1-day adult  (626) carcass, 4-day adult  (418) carcass, 20-day adult  (1877) ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male  (152) accessory gland, mated 4-day male  30 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8    58 head, virgin 1-day female  (437) head, virgin 4-day female  (244) head, virgin 20-day female  (2809) head, mated 1-day female  (175) head, mated 4-day female  (321) head, mated 20-day female  (1386) head, mated 1-day male  (304) head, mated 4-day male  (525) head, mated 20-day male  (1368) salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    55 digestive system, 4-day adult    25 digestive system, 20-day adult  107 fat body, larvae L3 wandering  (633) fat body, white prepupae    51 fat body, pupae P8  115 carcass, larvae L3 wandering    60 carcass, 1-day adult  (626) carcass, 4-day adult  (418) carcass, 20-day adult  (1877) ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male  (152) accessory gland, mated 4-day male    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    8 central nervous system, larvae L3    17 central nervous system, pupae P8    58 head, virgin 1-day female    437 head, virgin 4-day female    244 head, virgin 20-day female    2809 head, mated 1-day female    175 head, mated 4-day female    321 head, mated 20-day female    1386 head, mated 1-day male    304 head, mated 4-day male    525 head, mated 20-day male    1368 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    5 digestive system, larvae L3 wandering    15 digestive system, 1-day adult    55 digestive system, 4-day adult    25 digestive system, 20-day adult    107 fat body, larvae L3 wandering    633 fat body, white prepupae    51 fat body, pupae P8    115 carcass, larvae L3 wandering    60 carcass, 1-day adult    626 carcass, 4-day adult    418 carcass, 20-day adult    1877 ovary, virgin 4-day female    2 ovary, mated 4-day female    0 testis, mated 4-day male    152 accessory gland, mated 4-day male    30 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2    54 larva L3 12hr old    142 larva L3 puffstage 1-2    262 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    121 white prepupae new    80 white prepupae 12hr    197 white prepupae 24hr    749 pupae 2d postWPP    291 pupae 3d postWPP    84 pupae 4d postWPP    100 adult male 01day    453 adult male 05day    524 adult male 30day    640 adult female 01day    374 adult female 05day    183 adult female 30day    511 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2  (54) larva L3 12hr old  (142) larva L3 puffstage 1-2  (262) larva L3 puffstage 3-6  (235) larva L3 puffstage 7-9  (121) white prepupae new  (80) white prepupae 12hr  (197) white prepupae 24hr  (749) pupae 2d postWPP  (291) pupae 3d postWPP  (84) pupae 4d postWPP  (100) adult male 01day  (453) adult male 05day  (524) adult male 30day  (640) adult female 01day  (374) adult female 05day  (183) adult female 30day  (511) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2    54 larva L3 12hr old  (142) larva L3 puffstage 1-2  (262) larva L3 puffstage 3-6  (235) larva L3 puffstage 7-9  (121) white prepupae new    80 white prepupae 12hr  (197) white prepupae 24hr  (749) pupae 2d postWPP  (291) pupae 3d postWPP    84 pupae 4d postWPP    100 adult male 01day  (453) adult male 05day  (524) adult male 30day  (640) adult female 01day  (374) adult female 05day  (183) adult female 30day  (511) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2    54 larva L3 12hr old    142 larva L3 puffstage 1-2    262 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    121 white prepupae new    80 white prepupae 12hr    197 white prepupae 24hr    749 pupae 2d postWPP    291 pupae 3d postWPP    84 pupae 4d postWPP    100 adult male 01day    453 adult male 05day    524 adult male 30day    640 adult female 01day    374 adult female 05day    183 adult female 30day    511 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2    54 larva L3 12hr old    142 larva L3 puffstage 1-2    262 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    121 white prepupae new    80 white prepupae 12hr    197 white prepupae 24hr    749 pupae 2d postWPP    291 pupae 3d postWPP    84 pupae 4d postWPP    100 adult male 01day    453 adult male 05day    524 adult male 30day    640 adult female 01day    374 adult female 05day    183 adult female 30day    511 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2  (54) larva L3 12hr old  (142) larva L3 puffstage 1-2  (262) larva L3 puffstage 3-6  (235) larva L3 puffstage 7-9  (121) white prepupae new  (80) white prepupae 12hr  (197) white prepupae 24hr  (749) pupae 2d postWPP  (291) pupae 3d postWPP  (84) pupae 4d postWPP  (100) adult male 01day  (453) adult male 05day  (524) adult male 30day  (640) adult female 01day  (374) adult female 05day  (183) adult female 30day  (511) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2    54 larva L3 12hr old  142 larva L3 puffstage 1-2  (262) larva L3 puffstage 3-6  (235) larva L3 puffstage 7-9  121 white prepupae new    80 white prepupae 12hr  (197) white prepupae 24hr  (749) pupae 2d postWPP  (291) pupae 3d postWPP    84 pupae 4d postWPP    100 adult male 01day  (453) adult male 05day  (524) adult male 30day  (640) adult female 01day  (374) adult female 05day  (183) adult female 30day  (511) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    1 embryo 12-14hr    1 embryo 14-16hr    1 embryo 16-18hr    0 embryo 18-20hr    0 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    5 larva L2    54 larva L3 12hr old    142 larva L3 puffstage 1-2    262 larva L3 puffstage 3-6    235 larva L3 puffstage 7-9    121 white prepupae new    80 white prepupae 12hr    197 white prepupae 24hr    749 pupae 2d postWPP    291 pupae 3d postWPP    84 pupae 4d postWPP    100 adult male 01day    453 adult male 05day    524 adult male 30day    640 adult female 01day    374 adult female 05day    183 adult female 30day    511 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1    73 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1  (73) embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1    73 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1    73 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1    73 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1  (73) embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1    73 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    0 embryonic 1182-4H    0 embryonic GM2    1 embryonic Kc167    1 embryonic S1    73 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    1 wing disc ML-DmD8    0 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    0 wing disc ML-DmD21    0 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    1 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    7 CNS ML-DmBG2-c2    8 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    54 cold shock, 4-day adult    48 heat shock, 4-day adult    94 Cadmium 50 mM 6 hrs, larvae L3    241 Cadmium 50 mM 12 hrs, larvae L3    49 Cadmium 50 mM 48 hrs, 4-day adult    76 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    79 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    46 Ethanol 2.5% 3 hrs, larvae L3    54 Ethanol 5% 3 hrs, larvae L3    134 Ethanol 10% 3 hrs, larvae L3    163 Caffeine 1.5 mg/ml 4 hrs, larvae L3    121 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    28 Caffeine 25 mg/ml 48 hrs, 4-day adult    49 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    72 Rotenone 2 μg 12 hrs, larvae L3    157 Rotenone 8 μg 12 hrs, larvae L3    197 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (54) cold shock, 4-day adult  (48) heat shock, 4-day adult  (94) Cadmium 50 mM 6 hrs, larvae L3  (241) Cadmium 50 mM 12 hrs, larvae L3  (49) Cadmium 50 mM 48 hrs, 4-day adult  (76) Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3  (79) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (60) Zinc 4.5 mM 48 hrs, 4-day adult  (46) Ethanol 2.5% 3 hrs, larvae L3  (54) Ethanol 5% 3 hrs, larvae L3  (134) Ethanol 10% 3 hrs, larvae L3  (163) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (121) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (28) Caffeine 25 mg/ml 48 hrs, 4-day adult  (49) Paraquat 5 mM 48 hrs, 4-day adult  (43) Paraquat 10 mM 48 hrs, 4-day adult  (72) Rotenone 2 μg 12 hrs, larvae L3  (157) Rotenone 8 μg 12 hrs, larvae L3  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    54 cold shock, 4-day adult    48 heat shock, 4-day adult    94 Cadmium 50 mM 6 hrs, larvae L3  (241) Cadmium 50 mM 12 hrs, larvae L3    49 Cadmium 50 mM 48 hrs, 4-day adult    76 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    79 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    46 Ethanol 2.5% 3 hrs, larvae L3    54 Ethanol 5% 3 hrs, larvae L3  (134) Ethanol 10% 3 hrs, larvae L3  (163) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (121) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    28 Caffeine 25 mg/ml 48 hrs, 4-day adult    49 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    72 Rotenone 2 μg 12 hrs, larvae L3  (157) Rotenone 8 μg 12 hrs, larvae L3  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    54 cold shock, 4-day adult    48 heat shock, 4-day adult    94 Cadmium 50 mM 6 hrs, larvae L3    241 Cadmium 50 mM 12 hrs, larvae L3    49 Cadmium 50 mM 48 hrs, 4-day adult    76 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    79 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    46 Ethanol 2.5% 3 hrs, larvae L3    54 Ethanol 5% 3 hrs, larvae L3    134 Ethanol 10% 3 hrs, larvae L3    163 Caffeine 1.5 mg/ml 4 hrs, larvae L3    121 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    28 Caffeine 25 mg/ml 48 hrs, 4-day adult    49 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    72 Rotenone 2 μg 12 hrs, larvae L3    157 Rotenone 8 μg 12 hrs, larvae L3    197 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    54 cold shock, 4-day adult    48 heat shock, 4-day adult    94 Cadmium 50 mM 6 hrs, larvae L3    241 Cadmium 50 mM 12 hrs, larvae L3    49 Cadmium 50 mM 48 hrs, 4-day adult    76 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    79 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    46 Ethanol 2.5% 3 hrs, larvae L3    54 Ethanol 5% 3 hrs, larvae L3    134 Ethanol 10% 3 hrs, larvae L3    163 Caffeine 1.5 mg/ml 4 hrs, larvae L3    121 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    28 Caffeine 25 mg/ml 48 hrs, 4-day adult    49 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    72 Rotenone 2 μg 12 hrs, larvae L3    157 Rotenone 8 μg 12 hrs, larvae L3    197 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (54) cold shock, 4-day adult  (48) heat shock, 4-day adult  (94) Cadmium 50 mM 6 hrs, larvae L3  (241) Cadmium 50 mM 12 hrs, larvae L3  (49) Cadmium 50 mM 48 hrs, 4-day adult  (76) Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3  (79) Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3  (60) Zinc 4.5 mM 48 hrs, 4-day adult  (46) Ethanol 2.5% 3 hrs, larvae L3  (54) Ethanol 5% 3 hrs, larvae L3  (134) Ethanol 10% 3 hrs, larvae L3  (163) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (121) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  28 Caffeine 25 mg/ml 48 hrs, 4-day adult  (49) Paraquat 5 mM 48 hrs, 4-day adult  (43) Paraquat 10 mM 48 hrs, 4-day adult  (72) Rotenone 2 μg 12 hrs, larvae L3  (157) Rotenone 8 μg 12 hrs, larvae L3  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    54 cold shock, 4-day adult    48 heat shock, 4-day adult    94 Cadmium 50 mM 6 hrs, larvae L3  (241) Cadmium 50 mM 12 hrs, larvae L3    49 Cadmium 50 mM 48 hrs, 4-day adult    76 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    79 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    46 Ethanol 2.5% 3 hrs, larvae L3    54 Ethanol 5% 3 hrs, larvae L3  134 Ethanol 10% 3 hrs, larvae L3  (163) Caffeine 1.5 mg/ml 4 hrs, larvae L3  121 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    28 Caffeine 25 mg/ml 48 hrs, 4-day adult    49 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    72 Rotenone 2 μg 12 hrs, larvae L3  (157) Rotenone 8 μg 12 hrs, larvae L3  (197) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    54 cold shock, 4-day adult    48 heat shock, 4-day adult    94 Cadmium 50 mM 6 hrs, larvae L3    241 Cadmium 50 mM 12 hrs, larvae L3    49 Cadmium 50 mM 48 hrs, 4-day adult    76 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    79 Copper 15 mM 48 hrs, 4-day adult    12 Zinc 5 mM 12 hrs, larvae L3    60 Zinc 4.5 mM 48 hrs, 4-day adult    46 Ethanol 2.5% 3 hrs, larvae L3    54 Ethanol 5% 3 hrs, larvae L3    134 Ethanol 10% 3 hrs, larvae L3    163 Caffeine 1.5 mg/ml 4 hrs, larvae L3    121 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    28 Caffeine 25 mg/ml 48 hrs, 4-day adult    49 Paraquat 5 mM 48 hrs, 4-day adult    43 Paraquat 10 mM 48 hrs, 4-day adult    72 Rotenone 2 μg 12 hrs, larvae L3    157 Rotenone 8 μg 12 hrs, larvae L3    197 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0022355 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6186-RA;CG6186-RB;CG6186-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Tsf1f05108 viable, with Scer\GAL4pnr-MD237 Tsf1GD6514 Sterility Allele fertile Tsf1f05108 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of Tsf1 Class Mutagen Stocks Known lesion Tsf1f05108 piggyBac transposase 2 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Tsf1 Class Mutagen Stocks Known lesion Tsf1GD6514 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tsf1KK103815 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tsf1NIG.6186R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6514} NA P{KK103815} NA P{NIG.6186R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}Tsf1f05108 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
olfactory behavior inferred from mutant phenotype (Sambandan et al., 2008)
Cellular Component
CV term Evidence References
extracellular region inferred from direct assay (Karlsson et al., 2004)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
ferric iron binding inferred from sequence or structural similarity (Law et al., 1997) inferred from sequence or structural similarity with EMBL:J03298 (FlyBase, 1992-) iron ion transmembrane transporter activity inferred from sequence or structural similarity with EMBL:J03298 (FlyBase, 1992-) non-traceable author statement (Lemaitre, 2000.12.20)
Biological Process
CV term Evidence References
cellular iron ion homeostasis inferred from sequence or structural similarity (Law et al., 1997) inferred from sequence or structural similarity with EMBL:J03298 (FlyBase, 1992-) defense response non-traceable author statement (Lemaitre, 2000.12.20) iron ion transport inferred from electronic annotation with InterPro:IPR001156, InterPro:IPR018195 (FlyBase Curators et al., 2004-) non-traceable author statement (Lemaitre, 2000.12.20)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Tsf1 - Adh experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Argk experimental knowledge based (Guruharsha et al., 2011) Tsf1 - CG10581 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tsf1 - CG16826 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - CG31343 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - CG32473 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - CG34205 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - CG4390 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tsf1 - CG5500 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Tsf1 - CG9890 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tsf1 - Cpr64Ac experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Fer1HCH experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Fer2LCH experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Gpdh experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Iap2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Tsf1 - Lsp2 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Nplp2 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Obp56d experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Rfabg experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Scp1 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Yp1 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Yp2 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - Yp3 experimental knowledge based (Guruharsha et al., 2011) Tsf1 - proPO-A1 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Tsf1 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0022355 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32821
Orthologs
OrthoDB Orthologs (27) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6WWS41 Dipteran inclusive ortholog search EOG6GB7FG Insect inclusive ortholog search EOG6D51SP Arthropod inclusive ortholog search EOG69GHXK Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6WWS41)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Tsf1     Drosophila simulans   Dsim\GD24854 Y   Drosophila sechellia   Dsec\GM22896 Y   Drosophila erecta   Dere\GG19163 Y   Drosophila yakuba   Dyak\Tsf1 Y   Drosophila ananassae   Dana\GF22435 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA22329 Y   Drosophila persimilis   Dper\GL26971 Y   Drosophila willistoni   Dwil\GK25660 Y   Drosophila virilis   Dvir\GJ15366 Y   Drosophila mojavensis   Dmoj\GI15012 Y   Drosophila grimshawi   Dgri\GH12424 Y
Orthologs in non-Drosophila Dipterans (EOG6GB7FG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL015458   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL015639   Anopheles gambiae Malaria mosquito  Agam\AGAP000376   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015785
Orthologs in non-Dipteran Insects (EOG6D51SP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Tsf1   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013617   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH13701   Atta cephalotes Leafcutter ant  Acep\ACEP23104   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21199   Linepithema humile Argentine ant  Lhum\LH17758   Pogonomyrmex barbatus Red harvester ant  Pbar\PB26174   Solenopsis invicta Red fire ant  Sinv\SINV19392   Bombyx mori Silkmoth  Bmor\BGIBMGA011424   Tribolium castaneum Red flour beetle  Tcas\TC002069
Orthologs in non-Insect Arthropods (EOG69GHXK)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_313287
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24854 Drosophila sechellia Dsec\GM22896 Drosophila erecta Dere\GG19163 Drosophila yakuba Dyak\Tsf1 Drosophila ananassae Dana\GF22435 Drosophila pseudoobscura pseudoobscura Dpse\GA22329 Drosophila persimilis Dper\GL26971 Drosophila willistoni Dwil\GK25660 Drosophila virilis Dvir\GJ15366 Drosophila mojavensis Dmoj\GI15012 Drosophila grimshawi Dgri\GH12424
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	18838 w1118 PBac{WH}Tsf1f05108
Harvard	- PBac{WH}Tsf1f05108
VDRC	v106479 P{KK103815}VIE-260B v14666 w1118; P{GD6514}v14666
Genomic Clones ( 2 )
	BACR03K10 BACR10E05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 740 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP08340
Other clones	yak-ad_transferrin
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT01934 AT04669 AT10126 AT12573 AT18537 AT18721 AT20483 AT28231 AT31465 GH01303 GH02082 GH02182 GH02726 GH02729 GH02857 GH03566 GH04272 GH04575 GH05390 GH05634 GH05645 GH06382 GH06763 GH07507 GH07993 GH08112 GH08129 GH08431 GH08743 GH09784 GH10501 GH10758 GH12131 GH12305 GH12886 GH12985 GH13688 GH13734 GH13921 GH14153 GH14178 GH14477 GH14488 GH14648 GH15124 GH16074 GH16134 GH16295 GH16312 GH16884 GH17206 GH17477 GH17626 GH17802 GH18185 GH18286 GH18710 GH18948 GH18970 GH19291 GH19375 GH19550 GH19684 GH19738 GH20013 GH20386 GH20819 GH21308 GH21719 GH21884 GH22117 GH22169 GH22292 GH22808 GH23018 GH23164 GH23335 GH23647 GH23864 GH24453 GH24882 GH25940 GH26885 GH26946 GH27149 GH27159 GH27611 GH27662 GH28779 LP05413 LP12545 LP15646 LP17070 RE03352 RH02026 RH05058 RH34677 RH36548 RH38470 RH38785 RH38860 RH38903 RH38986 RH39017 RH39222 RH40214 RH54907 RH56929 RH60411 RH63906 RH69446
Other clones	16389 36645 37352 48484 50747 101755 104879 144535 160319 bs29a02 Dmel_neb_009615_0449_3642 Dmel_neb_010819_0622_3005 Dmel_neb_011862_0948_3153 Dmel_neb_013770_0580_0485 Dmel_neb_014304_0882_2091 EC052520 EC054507 EK127728 EK147360 EK155635 EK168053 EK172834 EK174956 EK177052 EK229973 EK250227 EK263150 GH02365 GH04217 GH04362 GH04883 GH06156 GH06157 GH07645 GH08871 GH12071 GH14643 GH14885 GH18792 GH20792 GH22045 GH24436 GH25224 GH27079 HL01008 HL01225 HL02668 IP04086 IP04186 IP04386 IP05134 IP06466 IP08869 IP08969 IP09169 IP09559 IP10269 IP12918 IP13268 IP13368 IP13468 RH01444 RH01566 RH02243 RH02406 RH02432 RH02725 RH03245 RH03271 RH03558 RH03561 RH03662 RH03980 RH04077 RH04122 RH04178 RH04329 RH04393 RH04440 RH04733 RH04816 RH04834 RH04867 RH04875 RH04878 RH04950 RH05027 RH05155 RH05171 RH05189 RH05285 RH05292 RH05330 RH05335 RH05383 RH05562 RH05623 RH05709 RH05712 RH05835 RH05888 RH05941 RH05982 RH06018 RH06054 RH06153 RH06179 RH06291 RH06307 RH06362 RH06363 RH06380 RH06383 RH06391 RH06403 RH06501 RH06620 RH06649 RH06665 RH06694 RH06713 RH06727 RH06789 RH06929 RH06937 RH06951 RH07256 RH07273 RH07293 RH07323 RH07422 RH07470 RH07724 RH07785 RH07914 RH07938 RH07952 RH08002 RH08101 RH08243 RH08393 RH08412 RH08437 RH08602 RH08809 RH08845 RH08847 RH08855 RH09219 RH09685 RH10076 RH10273 RH10278 RH10654 RH10762 RH11191 RH11312 RH12019 RH12034 RH12131 RH12207 RH12219 RH12339 RH12891 RH13948 RH14295 RH14365 RH14686 RH14776 RH14791 RH14806 RH14958 RH15361 RH16031 RH16790 RH16910 RH17141 RH17523 RH17618 RH18163 RH18175 RH18446 RH18535 RH18621 RH18722 RH18914 RH19834 RH19915 RH19939 RH20148 RH20241 RH20722 RH20874 RH21001 RH21211 RH21955 RH22192 RH22666 RH22688 RH23051 RH23189 RH23222 RH23454 RH23571 RH23970 RH24083 RH24107 RH24156 RH24183 RH24190 RH24415 RH24433 RH24685 RH24986 RH25229 RH25233 RH25268 RH25332 RH25362 RH25392 RH25468 RH25934 RH26143 RH26381 RH26384 RH26627 RH26802 RH26815 RH26872 RH26930 RH27059 RH27295 RH27314 RH27952 RH28027 RH28194 RH28271 RH28382 RH28507 RH28810 RH29012 RH29019 RH29068 RH29182 RH29386 RH29490 RH30191 RH30231 RH30233 RH30387 RH30816 RH31062 RH31133 RH31139 RH31270 RH31310 RH31385 RH31417 RH31455 RH31548 RH31557 RH31596 RH31603 RH31679 RH31731 RH32421 RH32474 RH32690 RH32691 RH32742 RH32989 RH33007 RH33011 RH33450 RH33591 RH33852 RH33923 RH34116 RH34223 RH34272 RH34283 RH34357 RH34478 RH34572 RH34726 RH34736 RH34962 RH34988 RH35036 RH35129 RH35427 RH35888 RH36069 RH36088 RH36115 RH36174 RH36307 RH36646 RH36694 RH36712 RH36775 RH36830 RH37010 RH37071 RH37250 RH37271 RH37274 RH37329 RH37359 RH37420 RH37686 RH37922 RH38030 RH38085 RH38204 RH38372 RH38429 RH38507 RH38655 RH38782 RH38875 RH39043 RH39171 RH39325 RH39523 RH39618 RH39763 RH39774 RH40194 RH40375 RH40447 RH40469 RH40627 RH40647 RH40714 RH41352 RH41371 RH41422 RH41510 RH41538 RH41539 RH41929 RH42147 RH42160 RH42184 RH42287 RH42351 RH42374 RH42458 RH42527 RH42601 RH42720 RH42805 RH42919 RH42968 RH43006 RH43022 RH43077 RH43307 RH43424 RH43528 RH43556 RH43754 RH44085 RH44164 RH44182 RH44643 RH44918 RH45054 RH45093 RH45145 RH45669 RH46375 RH46440 RH46444 RH46628 RH46636 RH46771 RH46839 RH46949 RH47105 RH47295 RH47331 RH47615 RH47665 RH47696 RH48107 RH48426 RH48517 RH48726 RH48780 RH48836 RH48873 RH48878 RH48918 RH48966 RH49325 RH49342 RH49686 RH49741 RH49809 RH49858 RH49868 RH49944 RH50215 RH50270 RH50283 RH50296 RH50381 RH50394 RH50540 RH50574 RH50640 RH50665 RH50761 RH51020 RH51415 RH51445 RH51608 RH51635 RH51812 RH51838 RH51960 RH52165 RH52258 RH52262 RH52374 RH52542 RH52543 RH52967 RH53052 RH53109 RH53238 RH53748 RH53887 RH53975 RH54007 RH54221 RH54341 RH54461 RH54568 RH54676 RH54974 RH55020 RH55079 RH55244 RH55290 RH55672 RH55825 RH55909 RH55962 RH55971 RH55978 RH56093 RH56104 RH56135 RH56291 RH56393 RH56541 RH56618 RH56785 RH56818 RH57110 RH57293 RH57506 RH57554 RH57558 RH57832 RH58015 RH58134 RH58419 RH58479 RH58545 RH58711 RH58721 RH58734 RH58759 RH58852 RH58863 RH58929 RH59020 RH59091 RH59245 RH59316 RH59343 RH59420 RH59942 RH60102 RH60141 RH60239 RH60418 RH60482 RH60528 RH60764 RH60942 RH61169 RH61496 RH61514 RH61646 RH61682 RH61762 RH61789 RH61795 RH61805 RH62080 RH62301 RH62539 RH62546 RH62710 RH62719 RH62782 RH62871 RH63021 RH63028 RH63029 RH63303 RH63373 RH63380 RH63446 RH63578 RH63673 RH63754 RH63873 RH63984 RH64077 RH64113 RH64137 RH64274 RH64342 RH64355 RH64383 RH64484 RH64516 RH64519 RH64585 RH65543 RH65861 RH65921 RH65932 RH65956 RH65991 RH66196 RH66224 RH66505 RH66512 RH66846 RH66887 RH67013 RH67045 RH67074 RH67084 RH67316 RH67613 RH67668 RH67678 RH68063 RH68084 RH68124 RH68411 RH68577 RH68621 RH68661 RH68692 RH68793 RH68826 RH68926 RH68944 RH68953 RH68980 RH69095 RH69241 RH69303 RH69357 RH69362 RH69527 RH69562 RH69646 RH69659 RH69667 RH69746 RH69767 RH69954 RH70080 RH70116 RH70186 RH70191 RH70205 RH70233 RH70402 RH70440 RH70559 RH70611 RH70729 RH70795 RH70832 RH70937 RH71411 RH71609 RH71685 RH71743 RH71811 RH71840 RH71940 RH71967 RH72088 RH72107 RH72130 RH72346 RH72358 RH72416 RH72438 RH72473 RH72567 RH73053 RH73940 RH74169 RH74263 RH74364 RH74365 RH74386 RH74437 RH74484 RH74577 RH74609 RH74635 RH74725 RP003268359
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0022355 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32821
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Transferrin CG6186 (Li, 1999.11) Source for identity of: Tsf1 Transferrin (Dunkov, 2001.8.25)
Source for database merge of	Source for merge of: Transferrin anon-EST:Posey265 (Bayraktaroglu, 2000.11.2)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078677 RefSeq (Proteins) • NP_523401 DDBJ / EMBL / GenBank • AA567347 AA568049 AA697506 AAC67389 AAF48831 AF061268 AF083317 AI106902 AI946631 Entrez Gene - A searchable database of RefSeq genes. • 32821 UniProtKB/TrEMBL • O97355 Q9VWV6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Transferrin family, iron binding site (IPR018195) Transferrin family (IPR001156) Transferrin, Insecta (IPR015560) Transferrin (IPR016357)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0022355 DRSC - Results from RNAi screens. • FBgn0022355 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0022355 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6186-RA;CG6186-RB;CG6186-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0022355 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32821 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32821 modMine - Data generated by the modENCODE project. • FBgn0022355
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	143958_at (Kristensen et al., 2005) anon-EST:Posey265   CG6186 (Karlsson et al., 2004, De Gregorio et al., 2001, Fulton et al., 2001, Mosallanejad et al., 2010, Lebo et al., 2009, Keleman et al., 2009.8.5, Monzo et al., 2010, Shibata et al., 2010, Cammarato et al., 2011, Puri et al., 2008) Tf (Yoshiga, 1998.4.23) Transferrin 1 (Edwards et al., 2006) Trf (Law et al., 1997) Tsf1 (Sambandan et al., 2008, Brun et al., 2006, Blanco et al., 2010, Dunkov and Georgieva, 2006, Karpac et al., 2011, Buchon et al., 2009, Monzo et al., 2010, Gerbasi et al., 2011, Parisi et al., 2004, Jumbo-Lucioni et al., 2010, Puri et al., 2008, Japanese National Institute of Genetics, 2012.5.21) TSF1 (Puri et al., 2005) tsf1 (Girardot et al., 2004)
Name Synonym	DTAF-transferrin (Strigini and Cohen, 2000) Transferrin (Puri and Minden, 2004, Boutros et al., 2002, Kimbrell and Beutler, 2001, Law et al., 1997, ) transferrin (Lemaitre, 2000.12.20, Yoshiga et al., 1999) Transferrin 1 (Edwards et al., 2006, Sackton and Clark, 2009, Georgieva et al., 2001, Pedersen et al., 2010, Lebo et al., 2009, Roxstrom-Lindquist et al., 2004, Hill-Burns and Clark, 2009, Shibata et al., 2010, Cammarato et al., 2011) Transferrin1 (Sambandan et al., 2008) transferrin 1 (Robinson et al., 2010) transferrin precursor (Yoshiga, 1998.4.23)
Secondary FlyBase IDs
	FBgn0025536
References ( 58 )
Generate a list of	All references relating to this gene ( 58 )
List References by type	Research paper  ( 30 ) Supplementary material  ( 6 ) Review  ( 1 ) Personal communication to FlyBase  ( 9 ) Abstract  ( 5 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Stock list  ( 1 ) Curated genome annotation  ( 3 )
Recent research papers ( 2 )
	Gerbasi et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(8): 3204--3209 Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis. [FBrf0213185] Karpac et al., 2011, Dev. Cell 20(6): 841--854 Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage. [FBrf0213873] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...