FlyBase Gene Report: Dmel\Sord2

General Information

Symbol

Dmel\Sord2

Species

D. melanogaster

Name

Sorbitol dehydrogenase 2

Annotation Symbol

CG4649

Feature Type

protein_coding_gene

FlyBase ID

FBgn0022359

Gene Model Status

Current

Stock Availability

9 publicly available

Enzyme Name (EC)

L-iditol 2-dehydrogenase (1.1.1.14)

Gene Summary

Sorbitol dehydrogenase 2 (Sord2) encodes an enzyme that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols including D-sorbitol and xylitol. It is involved in the biosynthesis of D-fructose from D-glucose and possibly in the catabolism of D-glucuronate to xylulose 5-phosphate. [Date last reviewed: 2025-03-27] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Sodh-2, Sodh2

Key Links

Genomic Location

Cytogenetic map

86C7-86C7

Sequence location

3R:10,876,384..10,878,257 [+]

Recombination map

3-50

RefSeq locus

NT_033777 REGION:10876384..10878257

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (4 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables L-iditol 2-dehydrogenase (NAD+) activity

inferred from mutant phenotype

(Cortese et al., 2020)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

enables L-iditol 2-dehydrogenase (NAD+) activity

traceable author statement

(Sano et al., 2022)

inferred from sequence or structural similarity with UniProtKB:Q00796

(Gene Ontology Curators, 2002-)

inferred from biological aspect of ancestor with PANTHER:PTN000190705

(GO Reference Genome Project, 2011-)

enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

inferred from electronic annotation with InterPro:IPR045306

(InterPro Project Members, 2004-)

enables oxidoreductase activity

inferred from electronic annotation with InterPro:IPR002328, InterPro:IPR020843

(InterPro Project Members, 2004-)

enables zinc ion binding

inferred from electronic annotation with InterPro:IPR002328

(InterPro Project Members, 2004-)

Biological Process (2 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

involved_in fructose biosynthetic process

inferred from genetic interaction with UniProtKB:O97479

(Hoshino et al., 2023, Sano et al., 2022)

involved_in sorbitol catabolic process

inferred from genetic interaction with UniProtKB:O97479

(Hoshino et al., 2023, Sano et al., 2022)

inferred from mutant phenotype

(Cortese et al., 2020)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in sorbitol catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000190705

(GO Reference Genome Project, 2011-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in cytosol

inferred from sequence or structural similarity with UniProtKB:Q64442

(Gene Ontology Curators, 2002-)

Gene Group (FlyBase)

L-IDITOL 2-DEHYDROGENASES

Pathway (FlyBase)

FRUCTOSE BIOSYNTHESIS

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

L-iditol 2-dehydrogenase (NAD+) activity

L-iditol + NAD(+) = keto-L-sorbose + NADH + H(+) (1.1.1.14)

Summaries

Gene Snapshot

Gene Group (FlyBase)

L-IDITOL 2-DEHYDROGENASES -: L-iditol 2-dehydrogenases catalyze the oxidation of L-iditol to L-sorbose with the reduction of NAD. These enzymes also act on D-sorbitol and xylitol and convert them to D-fructose and D-xylulose. (Adapted from 10.1006/jcht.1996.0099).

Pathway (FlyBase)

FRUCTOSE BIOSYNTHESIS -: Fructose can be produced in the cytosol from glucose via the production of the polyol, sorbitol. Fructose synthesis from dietary glucose is used as a feedback mechanism to regulate glucose metabolic pathways. (Adapted from FBrf0253831.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Sord2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry O96299)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.53

Gene model reviewed during 5.55

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Sord2-RA

FBtr0082324

NM_079587

1346

360

Additional Transcript Data and Comments

Reported size (kB)

1.3 (northern blot)

(Luque et al., 1998)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Sord2-PA

FBpp0081800

38.7

360

6.82

O96299

NP_524311

AAF54573

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

360 (aa)

(Luque et al., 1998)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

O96299

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sord2 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Sodh-2_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

0.36

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism | faint | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

amnioserosa

(Fisher et al., 2012)

embryonic stage 11 -- 12

yolk nucleus

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic/larval midgut

(Fisher et al., 2012)

yolk nucleus

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

(Luque et al., 1998)

pupal stage

(Luque et al., 1998)

adult stage

(Luque et al., 1998)

Additional Descriptive Data

Sord1 and Sord2 transcripts are detected in larval and adult stages, and at low levels in pupal stages. Sord1 is the major transcript in all stages studied.

(Luque et al., 1998)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Sord2 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Sord2

View exonic expression by tissue for Dmel\Sord2

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0022359

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

41313/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0022359

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0022359

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0022359

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG4649

Flygut - An atlas of the Drosophila adult midgut

FBgn0022359

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\Sord2

Stages(s) 11-12
Stages(s) 13-16

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 5 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Sord2

Transgenic constructs containing regulatory region of Sord2

Aberrations (Deficiencies and Duplications) ( 2 )

Inferred from experimentation ( 2 )

Gene disrupted in

Df(3R)Exel6159

(Ryder, 2004.4.26)

Df(3R)Exel7306

(Ryder, 2004.4.26)

Inferred from location ( 6 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^Mef2.PR

Sord2^GD16568

viable, with Scer\GAL4^pnr-MD237

viable, with Scer\GAL4^tin.CΔ4

Other Phenotypes

Allele

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

Sord2^GD11386

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (9)

Hsap\SORD

14 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (6)

Rnor\Sord

14 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (6)

Mmus\Sord

13 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (10)

Xtro\sord

8 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Danio rerio (Zebrafish) (6)

Drer\sord

14 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (7)

Cele\R04B5.5

14 of 14

Yes

Cele\R04B5.6

13 of 14

Yes

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (6)

Agam\AgaP_AGAP003584

12 of 12

Yes

Agam\AgaP_AGAP003581

7 of 12

Yes

Agam\AgaP_AGAP003582

7 of 12

Yes

Agam\AgaP_AGAP003583

7 of 12

Yes

Agam\AgaP_AGAP010499

1 of 12

Agam\AgaP_AGAP011633

1 of 12

Arabidopsis thaliana (thale-cress) (21)

Atha\AT5G51970

13 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Atha\CAD2

1 of 13

Yes

Atha\CAD3

1 of 13

Yes

Atha\CAD5

1 of 13

Yes

Atha\CAD6

1 of 13

Yes

Atha\CAD9

1 of 13

Yes

Atha\ELI3-1

1 of 13

Yes

Atha\ELI3-2

1 of 13

Yes

Atha\HOT5

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (18)

Scer\SOR1

12 of 13

Yes

Scer\SOR2

12 of 13

Yes

Scer\XYL2

11 of 13

Yes

Scer\BDH2

5 of 13

Yes

Scer\BDH1

4 of 13

Yes

Scer\ADH6

2 of 13

Yes

Scer\ADH7

2 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (3)

Spom\tms1

12 of 12

Yes

Spom\SPBC1198.01

3 of 12

Yes

Spom\SPBC1539.07c

1 of 12

Escherichia coli (enterobacterium) (12)

Ecol\ydjJ

9 of 11

Yes

Ecol\idnD

5 of 11

Yes

Ecol\rspB

5 of 11

Yes

Ecol\gatD

4 of 11

Yes

Ecol\lgoD

4 of 11

Yes

Ecol\tdh

3 of 11

Yes

Ecol\ybdR

2 of 11

Yes

Ecol\ydjL

2 of 11

Yes

Ecol\yggP

2 of 11

Yes

Ecol\yphC

2 of 11

Yes

Ecol\adhP

1 of 11

Yes

Ecol\ycjQ

1 of 11

Yes

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Sord2. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (6)

Sord1

12 of 13

Sordl

5 of 13

Fdh

2 of 13

Drat

1 of 13

Mecr

1 of 13

Rtn4ip1

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

neuronopathy, distal hereditary motor, autosomal recessive 8

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 2 )

Allele

Disease

Evidence

References

Sord2^MB01265

model of autosomal recessive distal hereditary motor neuronopathy 8

CEC

(Cortese et al., 2020)

Sord2^HMC03582

model of autosomal recessive distal hereditary motor neuronopathy 8

CEC with Sord1^HMS01028

(Cortese et al., 2020)

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

SORD; sorbitol dehydrogenase

model of autosomal recessive distal hereditary motor neuronopathy 8

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

SORD; sorbitol dehydrogenase

14 of 14

182500

NEURONOPATHY, DISTAL HEREDITARY MOTOR, AUTOSOMAL RECESSIVE 8; HMNR8

autosomal recessive distal hereditary motor neuronopathy 8

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Sord2 - Sord1

two hybrid

(Hu et al., 2017.6.13)

Sord2 - Vta1

two hybrid

(Hu et al., 2017.6.13)

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Sord1|Sord2

suppressible

Mondo

(Sano et al., 2022)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

upd1

suppressible

Sord2

(Mukherjee et al., 2006)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0022359

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

FRUCTOSE BIOSYNTHESIS

External Links

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-50

Cytogenetic map

86C7-86C7

Sequence location

3R:10,876,384..10,878,257 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

86C7-86C7

Limits computationally determined from genome sequence between P{EP}EP3340^EP3340 and P{PZ}tho¹&P{PZ}l(3)04629⁰⁵²⁷⁵

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

86D-86D

(Luque, 1997.4.30)

86D-86D

(determined by in situ hybridisation)

(Luque et al., 1998)

Experimentally Determined Recombination Data

Location

3-50

(FlyBase, 2016)

3-47.2

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

36187

y¹ w^*; Mi{MIC}Sord2^MI03065

23039

y¹ w^67c23; Mi{ET1}Sord2^MB01265

79570

y¹ sc^* v¹ sev²¹; P{TOE.GS03161}attP40

53353

y¹ sc^* v¹ sev²¹; P{TRiP.HMC03582}attP40

77073

y¹ sc^* v¹ sev²¹; P{TKO.GS00862}attP40/CyO

FlyORF

F003226

M{UAS-Sord2.ORF.3xHA.GW}ZH-86Fb

VDRC

v46701

w¹¹¹⁸; P{GD16568}v46701

v26585

w¹¹¹⁸; P{GD11386}v26585/TM3

v342697

P{hsFLP}1, y1 w1118; P{HD_CFD01234}attP40/CyO-GFP

Genomic Clones (26)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (154)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD47736

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0022359

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0022359

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Additional comments

Renamed from 'Sodh2' to 'Sord2' to implement the more commonly used symbol for this gene across species.

(Zaru and Marygold, 2025)

Nomenclature History

Source for database identify of

Source for identity of: Sodh2 Sodh-2

(FlyBase, 2009-)

Source for identity of: Sord2 Sodh2

(Zaru and Marygold, 2025)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

CG4649

(Hosono et al., 2015, Ni et al., 2010.12.1)

DM_7299382

(Nordling et al., 2002)

SODH-2

(Choudhary et al., 1992)

Sdh

(Luque, 1997.4.30)

Sdh-2

(Luque et al., 1998)

Sodh-2

(Sano et al., 2022, Cho et al., 2020, Santana et al., 2020, Meltzer et al., 2019, Hu et al., 2017.6.13, Seong et al., 2017, Transgenic RNAi Project members, 2017-, Awofala et al., 2012, Kong et al., 2010, Yamamoto et al., 2009.2.25, Allen and Spradling, 2008, Mukherjee et al., 2006)

Sodh2

(Zhu et al., 2023, Gruntenko et al., 2021, Cortese et al., 2020, Kitani-Morii and Noto, 2020)

Sord2

(Zaru and Marygold, 2025)

Name Synonyms

Sorbitol dehydrogenase

(Sano et al., 2022)

Sorbitol dehydrogenase 2

(Morozova et al., 2006)

Sorbitol dehydrogenase-2

(Choudhary et al., 1992)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 48 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

41313

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

O96299

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

O96299

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

O96299

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0022359

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

41313/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0022359

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0022359

FlyMine - An integrated database for Drosophila genomics

FBgn0022359

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG4649

MARRVEL_MODEL - MARRVEL (model organism gene)

41313

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0022359

DroID - A comprehensive database of gene and protein interactions.

FBgn0022359

DRSC - Results frm RNAi screens

FBgn0022359

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Sodh-2_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0022359

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0022359

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG4649

Flygut - An atlas of the Drosophila adult midgut

FBgn0022359

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0022359

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

References (60)

The following external sites may use different assemblies or annotations than FlyBase.

0.36

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