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Gene Dmel\vimar

General Information
Symbol	Dmel\vimar	Species	D. melanogaster
Name	visceral mesodermal armadillo-repeats	Annotation symbol	CG3572
Feature type	protein_coding_gene	FlyBase ID	FBgn0022960
Gene Model Status	Current	Stock availability	14 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map	2-
Cytogenetic map	42E1-42E1	Sequence location	2R:2,862,787..2,873,214 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene visceral mesodermal armadillo-repeats is referred to in FlyBase by the symbol Dmel\vimar (CG3572, FBgn0022960). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: Ral GTPase binding. There is experimental evidence that it is involved in the biological process: tricarboxylic acid cycle. 19 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo; Armadillo-like helical; Armadillo-type fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval hindgut, larval Malpighian tubules, larval trachea, inseminated spermatheca. Comments on Affy2 ProbeSet: ProbeSet 1624721_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of vimar. Gene sequence location is 2R:2862787..2873214.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	References Knowles-Barley, 2011.8.24, BrainTrap expression curation.
FB2012_01	Sequence features BKN20697 HFA05026 BKN45156
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 42E1-42E1   Limits computationally determined from genome sequence between P{EP}EP2303&P{EP}EP2105 and P{lacW}vimark16722
Experimentally Determined Cytological Location
Cytogenetic map Notes References 42E2-42E3     (Lo, 1997.11.12) 42E3-42E4   (determined by in situ hybridisation)   (Spradling et al., 1999) 42E2-42E3   (determined by in situ hybridisation)   (Lo and Frasch, 1998) 42E3-42E4   (determined by in situ hybridisation)   (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location	2- (Lo, 1997.11.12, )
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\vimar for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone appears problematic (SD10607): incomplete CDS (approximately 40aa short at amino terminus).
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) vimar-RB FBtr0086183  NM_057957   3467   634 vimar-RC FBtr0086182  NM_206045   3470   635
Additional Transcript Data & Comments
Reported size (kB)	3.7, 3.2 (northern blot) (Lo and Frasch, 1998)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein vimar-PB   FBpp0089175   70.3   634   4.80     NP_477305   AAF57418 vimar-PC   FBpp0085514   70.3   635   4.80     NP_995767   AAS64794
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Armadillo (IPR000225) Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA264054   AE013599 AAF57418   AE013599 AAS64794   AC009342   AF034421 AAB87984   AF171836   AI543723   AQ034041   AQ073451   AW944649   AY069865 AAL40010   BG632230   BI234816   BI236082   BI239686   BI361463   BI366559   BI369912   BI370163   BI370510   BI373080   BI375493   BI482412   BI578322   BT004891 AAO47869   BT044558   BT125966   CL610247   CO179008   CO186187   CO282850   CO286011   CO288851   CO293437   CO294562   CO296101   CO297620   CO316435   CO340511   CO341536   CZ469482   CZ469685   CZ471886   CZ476388   CZ482049   EC058361   EC077605   EC085050   EC085333   EC194441   EC195959   EC196267   EC201240   EC221175   EC235237   EC238492   EC247269   EC260435   EV576841   GH942752   GH942779   GH944025   GH944474   GH944531   GH945289   GH946671   GH947416   GH947500   GH948511   GH948740   GH948942   GH949910   GH950242   GH950368   GH952421   GH953101   GH954118   GH955458   GH958902   GH960207   GH960576   GH960657   GH962419   GH962520   GH965587   GH967944   GH968331   GH970171   GH970556   GH970817   GH970970   GH970986   GH971061   GH974550   GH975065   GH975733   GH975769   GH977768   GH977885   GH978290   GH978921   GH979839   GH979994   GH981099   GH981460   GH983151   GH984082   GH984118
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O44116 Q86LF4 Q8T996 A1Z6S7 A1Z6S6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage -- larval stage     (Lo and Frasch, 1998) embryonic stage 1 -- 4   organism   (Lo and Frasch, 1998) Comment:0-2 hrs AEL embryonic stage 9 -- 17     (Lo and Frasch, 1998) Comment:4-24 hrs AEL first instar larval stage     (Lo and Frasch, 1998) adult stage | female   organism   (Lo and Frasch, 1998)
Additional Descriptive Data
	The 3.2 kb vimar maternal transcript is detected at high levels in adult females, and in early embryos. Transcripts are detected at very low levels through the first instar larval stage. (Lo and Frasch, 1998) vimar zygotic transcripts are first detected in embryos at 4 hours, and until the first instar larval stage. (Lo and Frasch, 1998)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0022960    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0022960 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0022960 expression level Developmental Stage   Expression Level embryo 00-02hr    4611 embryo 02-04hr    2896 embryo 04-06hr    3064 embryo 06-08hr    3325 embryo 08-10hr    3905 embryo 10-12hr    3091 embryo 12-14hr    2492 embryo 14-16hr    2147 embryo 16-18hr    1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9    1597 white prepupae new    2115 white prepupae 12hr    1931 white prepupae 24hr    2038 pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day    2095 adult female 30day    2060 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4611) embryo 02-04hr  (2896) embryo 04-06hr  (3064) embryo 06-08hr  (3325) embryo 08-10hr  (3905) embryo 10-12hr  (3091) embryo 12-14hr  (2492) embryo 14-16hr  (2147) embryo 16-18hr  (1416) embryo 18-20hr  (971) embryo 20-22hr  (961) embryo 22-24hr  (1057) larva L1  (1102) larva L2  (794) larva L3 12hr old  (541) larva L3 puffstage 1-2  (554) larva L3 puffstage 3-6  (1091) larva L3 puffstage 7-9  (1597) white prepupae new  (2115) white prepupae 12hr  (1931) white prepupae 24hr  (2038) pupae 2d postWPP  (1184) pupae 3d postWPP  (631) pupae 4d postWPP  (573) adult male 01day  (420) adult male 05day  (404) adult male 30day  (455) adult female 01day  (1256) adult female 05day  (2095) adult female 30day  (2060) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4611) embryo 02-04hr  (2896) embryo 04-06hr  (3064) embryo 06-08hr  (3325) embryo 08-10hr  (3905) embryo 10-12hr  (3091) embryo 12-14hr  (2492) embryo 14-16hr  (2147) embryo 16-18hr  1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9  (1597) white prepupae new  (2115) white prepupae 12hr  (1931) white prepupae 24hr  (2038) pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day  (2095) adult female 30day  (2060) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4611 embryo 02-04hr    2896 embryo 04-06hr    3064 embryo 06-08hr    3325 embryo 08-10hr    3905 embryo 10-12hr    3091 embryo 12-14hr    2492 embryo 14-16hr    2147 embryo 16-18hr    1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9    1597 white prepupae new    2115 white prepupae 12hr    1931 white prepupae 24hr    2038 pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day    2095 adult female 30day    2060 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4611 embryo 02-04hr    2896 embryo 04-06hr    3064 embryo 06-08hr    3325 embryo 08-10hr    3905 embryo 10-12hr    3091 embryo 12-14hr    2492 embryo 14-16hr    2147 embryo 16-18hr    1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9    1597 white prepupae new    2115 white prepupae 12hr    1931 white prepupae 24hr    2038 pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day    2095 adult female 30day    2060 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0022960 expression level Developmental Stage   Expression Level embryo 00-02hr    4611 embryo 02-04hr    2896 embryo 04-06hr    3064 embryo 06-08hr    3325 embryo 08-10hr    3905 embryo 10-12hr    3091 embryo 12-14hr    2492 embryo 14-16hr    2147 embryo 16-18hr    1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9    1597 white prepupae new    2115 white prepupae 12hr    1931 white prepupae 24hr    2038 pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day    2095 adult female 30day    2060 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4611) embryo 02-04hr  (2896) embryo 04-06hr  (3064) embryo 06-08hr  (3325) embryo 08-10hr  (3905) embryo 10-12hr  (3091) embryo 12-14hr  (2492) embryo 14-16hr  (2147) embryo 16-18hr  (1416) embryo 18-20hr  (971) embryo 20-22hr  (961) embryo 22-24hr  (1057) larva L1  (1102) larva L2  (794) larva L3 12hr old  (541) larva L3 puffstage 1-2  (554) larva L3 puffstage 3-6  (1091) larva L3 puffstage 7-9  (1597) white prepupae new  (2115) white prepupae 12hr  (1931) white prepupae 24hr  (2038) pupae 2d postWPP  (1184) pupae 3d postWPP  (631) pupae 4d postWPP  (573) adult male 01day  (420) adult male 05day  (404) adult male 30day  (455) adult female 01day  (1256) adult female 05day  (2095) adult female 30day  (2060) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4611) embryo 02-04hr  (2896) embryo 04-06hr  (3064) embryo 06-08hr  (3325) embryo 08-10hr  (3905) embryo 10-12hr  (3091) embryo 12-14hr  (2492) embryo 14-16hr  2147 embryo 16-18hr  1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9  1597 white prepupae new  2115 white prepupae 12hr  1931 white prepupae 24hr  2038 pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day  2095 adult female 30day  2060 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4611 embryo 02-04hr    2896 embryo 04-06hr    3064 embryo 06-08hr    3325 embryo 08-10hr    3905 embryo 10-12hr    3091 embryo 12-14hr    2492 embryo 14-16hr    2147 embryo 16-18hr    1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9    1597 white prepupae new    2115 white prepupae 12hr    1931 white prepupae 24hr    2038 pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day    2095 adult female 30day    2060 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4611 embryo 02-04hr    2896 embryo 04-06hr    3064 embryo 06-08hr    3325 embryo 08-10hr    3905 embryo 10-12hr    3091 embryo 12-14hr    2492 embryo 14-16hr    2147 embryo 16-18hr    1416 embryo 18-20hr    971 embryo 20-22hr    961 embryo 22-24hr    1057 larva L1    1102 larva L2    794 larva L3 12hr old    541 larva L3 puffstage 1-2    554 larva L3 puffstage 3-6    1091 larva L3 puffstage 7-9    1597 white prepupae new    2115 white prepupae 12hr    1931 white prepupae 24hr    2038 pupae 2d postWPP    1184 pupae 3d postWPP    631 pupae 4d postWPP    573 adult male 01day    420 adult male 05day    404 adult male 30day    455 adult female 01day    1256 adult female 05day    2095 adult female 30day    2060 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0022960    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0022960 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval hindgut, larval Malpighian tubules, larval trachea, inseminated spermatheca. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0022960 expression level Tissue   Expression Level Larval Central Nervous System    614.575 Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (614.575) Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    614.575 Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    614.575 Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0022960 expression level Tissue   Expression Level Larval Central Nervous System    614.575 Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  614.575 Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    614.575 Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    614.575 Larval Midgut    78 Larval Hindgut    127 Larval Malpighian Tubules    103 Larval Fat Body    50.9 Larval Salivary Gland    79.6 Larval Trachea    108.9 Larval Carcass    71.6 Adult Head    77.8 Adult Eye    67.775 Adult Brain    276.9 Adult Thoracic-Abdominal Ganglion    160.5 Adult Crop    76.9 Adult Midgut    36.1 Adult Hindgut    42.2 Adult Malpighian Tubules    34.2 Adult Fat Body    34.7 Adult Salivary Gland    56 Adult Heart    41.625 Adult VirginFemale Spermatheca    99.4 Adult InseminatedFemale Spermatheca    100.7 Adult Ovary    31.6 Adult Testis    11.8 Adult Male Accessory Gland    48.1 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    77.8   NA  Eye    67.775   NA  Brain    276.9   614.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    160.5   NA  Crop    76.9   78  Midgut    36.1   127  Hindgut    42.2   103  Malpighian Tubules    34.2   50.9  Fat Body    34.7   79.6  Salivary Gland    56   NA  Heart    41.625   108.9  Trachea    NA   NA  VirginFemale Spermatheca    99.4   NA  InseminatedFemale Spermatheca    100.7   NA  Ovary    31.6   NA  Testis    11.8   NA  Male Accessory Gland    48.1   71.6  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_30
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0022960 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3572-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for vimar Stages(s) 1-3 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive vimar09 vimarF39-167 vimark10203b vimark16707 vimark16722 viable vimarB6-2-30 viable, with Scer\GAL4pnr-MD237 vimarGD11015 Sterility Allele fertile vimarB6-2-30 Phenotype manifest in Allele
Classical Alleles ( 16 )
For All Classical Alleles Show
Allele of vimar Class Mutagen Stocks Known lesion vimark16722 P-element activity 2 -- vimar09 1 Yes vimarc04743 piggyBac transposase 1 -- vimarc05022 piggyBac transposase 1 -- vimard00911 P-element activity 1 -- vimare04300 piggyBac transposase 1 -- vimarEY09646 P-element activity 1 -- vimark16707 P-element activity 1 -- vimarMB05601 1 -- vimarNP0902 1 -- vimarB6-2-30 P-element activity 0 Yes vimarCPTI002285 piggyBac transposase 0 Yes vimard08729 P-element activity 0 -- vimarEP2275 P-element activity 0 -- vimarF39-167 Delta2-3 0 Yes vimark10203b P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of vimar Class Mutagen Stocks Known lesion vimarGD11015 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes vimarHMS00745 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes vimarKK100601 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)cn88b (Lo and Frasch, 1998) Df(2R)Drlrv7 (Lo and Frasch, 1998) Df(2R)Drlrv17 (Lo and Frasch, 1998) Df(2R)Drlrv28 (Lo and Frasch, 1998) Df(2R)Exel6051 (Ryder, 2004.4.26) Df(2R)nap2 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2R)nap16 (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2R)Δ42E (Lin et al., 2005)
Not disrupted in	Df(2L)cact-255rv64 (BDGP Project Members, 1994-1999) Df(2L)r10 (BDGP Project Members, 1994-1999) Df(2R)cn88b (Spradling et al., 1999, BDGP Project Members, 1994-1999) Df(2R)Drlrv5 (BDGP Project Members, 1994-1999) Df(2R)pk78k (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11015} NA P{KK100601} NA P{TRiP.HMS00745} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}l(2)SH1513SH1513 No P{lacW}vimarB6-2-30 No P{lacW}vimark10203b No P{lacW}vimark16707 No P{lacW}vimark16722 No insertion of mobile activating element P{EP}vimarEP2275 NA P{EPgy2}vimarEY09646 NA P{GSV1}C109C109 NA P{GSV1}C504C504 NA P{XP}vimard00911 NA P{XP}vimard08729 NA miscellaneous insertions P{PTT-GB}CG17002CB05094 NA P{UASp-YFP.Rab8.T22N}vimar09 NA PBac{681.P.FSVS-1}vimarCPTI002285 NA PBac{PB}vimarc04743 NA PBac{PB}vimarc05022 NA PBac{RB}vimare04300 NA insertion of enhancer trap binary system Mi{ET1}vimarMB05601 No P{GawB}vimarNP0902 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
tricarboxylic acid cycle inferred from direct assay (Chen et al., 2008)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
Ral GTPase binding inferred from sequence or structural similarity with EMBL:AJ005870 (FlyBase, 1992-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions vimar allele Gene References unspecified trc (He et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61498 DroID - A comprehensive database of gene and protein interactions. • FBgn0022960 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35609
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11753 Dere\GG10781 Dgri\GH20393 Dmoj\GI20062 Dper\GL10958 Dpse\GA24543 Dsec\GM20831 Dsim\GD10283 Dvir\GJ14960 Dwil\GK21536 Dyak\GE24302
Curated drosophilid orthologs	Dpse\GA17530
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL001252-PA Aedes aegypti (mosquito) AGAP005262-PA Anopheles gambiae (mosquito) XP_396135.3 Apis mellifera (honey bee) 235882 Branchiostoma floridae (lancelet) 235893 Branchiostoma floridae (lancelet) BGIBMGA010911-PA Bombyx mori (silk worm) ENSBTAP00000045312 Bos taurus (bovine) ENSCAFP00000015079 Canis familiaris (dog) CPIJ002316 Culex pipens (mosquito) ENSCPOP00000001641 Cavia porcellus (guinea pig) 163268 Capitella spl (polychaete worm) ENSDARP00000009726 Danio rerio (zebra fish) ENSDARP00000072896 Danio rerio (zebra fish) ENSECAP00000018715 Equus caballus (horse) ENSGACP00000001199 Gymnopilus aculeatus (mushroom) ENSGALP00000019931 Gallus gallus (chicken) 161781 Hypsipyla robusta (cedar shoot borer) ENSP00000340454 Homo sapiens (human) ISCW002472-PA Ixodes scapularis (deer tick) 228970 Lottia gigantea (owl limpet) 36800 Monocosta brevicollis (choanoflagellate) ENSMODP00000025917 Monodelphis domestica (gray opossum) ENSMMUP00000029506 Macaca mulatta (rhesus monkey) ENSMUSP00000096173 Mus musculus (house mouse) 238452 Nematostella vectensis (starlet anemone) ENSORLP00000015022 Oryzias latipes (japanese killifish) PHUM011466-PA Pediculus humanus (human body louse) ENSPPYP00000016684 Pongo pygmaeus (orangutan) ENSPTRP00000053403 Pan troglodytes (chimpanzee) ENSRNOP00000052297 Rattus norvegicus (norway rat) SPCC1494.03 Schizosaccharomyces pombe (fission yeast) XP_001180733.1 Strongylocentrotus purpuratus (purple sea urchin) 54425 Trichoplax adhaerens (metazoa) XP_974912.1 Tribolium castaneum (red flour beetle) ENSTRUP00000012749 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000016401 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12655 LH12721 ISCW002472 FBgn0241425 FBgn0223528 FBgn0202163 FBgn0182056 FBgn0175712 FBgn0245934 FBgn0148568 FBgn0142798 FBgn0127856 FBgn0103086 FBgn0088793 CPIJ002316 BGIBMGA010911 GB18319 AGAP005262 AAEL001252 PHUM605250 GLEAN_02934
Stocks & Reagents
Stocks Listed in FlyBase ( 14 )
Bloomington	25302 w1118; Mi{ET1}vimarMB05601 32951 y1 sc* v1; P{TRiP.HMS00745}attP2 11199 y1 w67c23; P{lacW}vimark16722/CyO 19780 y1 w67c23; P{EPgy2}vimarEY09646/CyO
Harvard	- P{XP}vimard00911 - PBac{PB}vimarc04743 - PBac{PB}vimarc05022 - PBac{RB}vimare04300
Kyoto	103811 w*; P{GawB}vimarNP0902 / CyO 103028 y1 w67c23 ; P{lacW}vimark16707 / CyO
VDRC	v105618 P{KK100601}VIE-260B v21686 w1118; P{GD11015}v21686
	More stocks available...
Genomic Clones ( 2 )
	BACR29G01 BACR36G11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 91 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE54322 RE57156 SD10607
Other clones	FI02061
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH05437 RE30587 RE32079 RE36253 RE45682 RE52127 RE56250 RE56580 RE60292 RE63331 RE65104 RE72183
Other clones	28754 45279 53211 65824 73389 75304 152941 161147 214349.29 CK01.17A.G11 CK01.73D.F4 CK01.79A.C4 CK01.88B.F3 Dmel_dig_012013_0657_2912 EK016726 EK058154 EK061442 EK069522 EK161445 EK170213 EK202921 EK207212 EK212705 EK264945 EP10806 EP12629 RP004019910 RP004096829 RP004118991 RP004135163 RP004144686 RP004174347 RP004175351 RP004180202 RP004189604 RP004194183 RP004195616 RP004201910 RP004202116 RP004208261 RP004208310 RP004213827 RP004217625 RP004231146 RP004232626 RP004233754 RP004240072 RP004241289 RP004243883 RP004247088 RP004247573 RP004254208 RP004255301 RP004258444 RP004261472 RP004274301 RP004279561 RP004335285 RP004336104 RP004350682 RP004361236 RP004418506 RP004419311 RP004419801 RP004421524 RP004425878 RP004431234 RP004456629 RP004461303 RP004491268 RP004522839 RP004525212 RP004542381 RP004543104 RP004547253
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0022960 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35609
Antibody Information
Other Information
Discoverer
Etymology
	Gene name is 'visceral mesodermal armadillo-repeats' based on the gene's tissue-specific expression and sequence of its encoded protein. (Lo and Frasch, 1998)
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: vimar anon-EST:Posey213 (Bayraktaroglu, 2000.11.2) Source for merge of: vimar l(2)k16722 (Spradling et al., 1999)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057957 NM_206045 RefSeq (Proteins) • NP_477305 NP_995767 DDBJ / EMBL / GenBank • AA264054 AAB87984 AAF57418 AAL40010 AAO47869 AAS64794 AC009342 AF034421 AF171836 AI543723 AQ034041 AQ073451 AW944649 AY069865 BI370510 BT004891 CL610247 CZ469482 CZ469685 CZ471886 CZ476388 CZ482049 Entrez Gene - A searchable database of RefSeq genes. • 35609 UniProtKB/TrEMBL • A1Z6S6 A1Z6S7 O44116 Q8T996 Q86LF4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Armadillo (IPR000225) Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61498 DroID - A comprehensive database of gene and protein interactions. • FBgn0022960 DRSC - Results from RNAi screens. • FBgn0022960 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0022960 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3572-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0022960 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35609 InParanoid A subset of ortholog calls from InParanoid. • AAEL001252-PA Aedes aegypti (mosquito) AGAP005262-PA Anopheles gambiae (mosquito) XP_396135.3 Apis mellifera (honey bee) 235882 Branchiostoma floridae (lancelet) 235893 Branchiostoma floridae (lancelet) BGIBMGA010911-PA Bombyx mori (silk worm) ENSBTAP00000045312 Bos taurus (bovine) ENSCAFP00000015079 Canis familiaris (dog) CPIJ002316 Culex pipens (mosquito) ENSCPOP00000001641 Cavia porcellus (guinea pig) 163268 Capitella spl (polychaete worm) ENSDARP00000009726 Danio rerio (zebra fish) ENSDARP00000072896 Danio rerio (zebra fish) ENSECAP00000018715 Equus caballus (horse) ENSGACP00000001199 Gymnopilus aculeatus (mushroom) ENSGALP00000019931 Gallus gallus (chicken) 161781 Hypsipyla robusta (cedar shoot borer) ENSP00000340454 Homo sapiens (human) ISCW002472-PA Ixodes scapularis (deer tick) 228970 Lottia gigantea (owl limpet) 36800 Monocosta brevicollis (choanoflagellate) ENSMODP00000025917 Monodelphis domestica (gray opossum) ENSMMUP00000029506 Macaca mulatta (rhesus monkey) ENSMUSP00000096173 Mus musculus (house mouse) 238452 Nematostella vectensis (starlet anemone) ENSORLP00000015022 Oryzias latipes (japanese killifish) PHUM011466-PA Pediculus humanus (human body louse) ENSPPYP00000016684 Pongo pygmaeus (orangutan) ENSPTRP00000053403 Pan troglodytes (chimpanzee) ENSRNOP00000052297 Rattus norvegicus (norway rat) SPCC1494.03 Schizosaccharomyces pombe (fission yeast) XP_001180733.1 Strongylocentrotus purpuratus (purple sea urchin) 54425 Trichoplax adhaerens (metazoa) XP_974912.1 Tribolium castaneum (red flour beetle) ENSTRUP00000012749 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000016401 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35609 modMine - Data generated by the modENCODE project. • FBgn0022960 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12655 LH12721 ISCW002472 FBgn0241425 FBgn0223528 FBgn0202163 FBgn0182056 FBgn0175712 FBgn0245934 FBgn0148568 FBgn0142798 FBgn0127856 FBgn0103086 FBgn0088793 CPIJ002316 BGIBMGA010911 GB18319 AGAP005262 AAEL001252 PHUM605250 GLEAN_02934
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-EST:Posey213   CG3572 (Molnar et al., 2006, Keleman et al., 2009.8.5, Fujiyama-Nakamura et al., 2009, Chen et al., 2008, Ni et al., 2010.12.1) l(2)k16722 (BDGP Project Members, 1994-1999, ) vimar (Jakobsen et al., 2007, Buszczak et al., 2007, Zhang et al., 2007, Molnar et al., 2006, Bakal et al., 2007, Kucherenko et al., 2008, Chen et al., 2008) Vimar (He et al., 2005)
Name Synonym	visceral mesodermal armadillo-repeats (Lo and Frasch, 1998)
Secondary FlyBase IDs
	FBgn0021806 FBgn0027729
References ( 37 )
Generate a list of	All references relating to this gene ( 37 )
List References by type	Research paper  ( 14 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 3 ) Computer file  ( 4 ) DNA/RNA sequence record  ( 1 )
Recent research papers ( 1 )
	Kucherenko et al., 2011, Dev. Biol. 352(2): 228--242 Stress and muscular dystrophy: a genetic screen for dystroglycan and dystrophin interactors in Drosophila identifies cellular stress response components. [FBrf0214383] Show all research papers ...