Gene Dmel\CRMP

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CRMP for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.48

Variable use of small exon; supported combination results in frameshift and premature stop in downstream exon.

Alternative translation stop created by use of multiphasic reading frames within coding region.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Low-frequency RNA-Seq exon junction(s) not annotated.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CRMP-RA

FBtr0089686

NM_057959

2575

589

CRMP-RB

FBtr0089685

NM_169070

2814

332

CRMP-RE

FBtr0114453

NM_169072

2590

594

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CRMP-PA

FBpp0088628

64.4

589

7.03

NP_477307

AAF52002

CRMP-PB

FBpp0088627

36.5

332

6.72

NP_730952

AAF52003

CRMP-PE

FBpp0112945

65.1

594

6.69

NP_730954

AAN13245

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Amidohydrolase 1 (IPR006680)

Metal-dependent hydrolase, composite domain (IPR011059)

Hydantoinase/dihydropyrimidinase (IPR011778)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

dorsal sensory complex proper primordium

Comment:reported as dorsal/lateral sensory complexes

embryonic brain

embryonic head sensory system

ventral midline

ventral nerve cord

ventral sensory complex primordium

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

(The modENCODE Consortium, 2010)

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression in all larval and adult organs/tissues ranges from low to undetected. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult fat body, adult salivary gland, adult spermathecae, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult crop, larval/adult hindgut, adult heart, larval fat body, adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		30
central nervous system, pupae P8		102
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		39
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		(30)
central nervous system, pupae P8		(102)
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		(29)
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		(39)
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		30
central nervous system, pupae P8		102
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		39
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		30
central nervous system, pupae P8		102
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		39
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		30
central nervous system, pupae P8		102
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		39
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		30
central nervous system, pupae P8		(102)
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		(39)
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		30
central nervous system, pupae P8		102
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		39
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		8
central nervous system, larvae L3		30
central nervous system, pupae P8		102
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		25
head, mated 1-day female		8
head, mated 4-day female		15
head, mated 20-day female		20
head, mated 1-day male		21
head, mated 4-day male		23
head, mated 20-day male		29
salivary gland, larvae L3 wandering		9
salivary gland, white prepupae		22
digestive system, larvae L3 wandering		1
digestive system, 1-day adult		3
digestive system, 4-day adult		3
digestive system, 20-day adult		2
fat body, larvae L3 wandering		3
fat body, white prepupae		39
fat body, pupae P8		26
carcass, larvae L3 wandering		10
carcass, 1-day adult		7
carcass, 4-day adult		9
carcass, 20-day adult		10
ovary, virgin 4-day female		1
ovary, mated 4-day female		1
testis, mated 4-day male		1
accessory gland, mated 4-day male		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		65
embryo 12-14hr		59
embryo 14-16hr		76
embryo 16-18hr		61
embryo 18-20hr		50
embryo 20-22hr		29
embryo 22-24hr		28
larva L1		29
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		34
white prepupae new		38
white prepupae 12hr		31
white prepupae 24hr		60
pupae 2d postWPP		111
pupae 3d postWPP		61
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		(65)
embryo 12-14hr		(59)
embryo 14-16hr		(76)
embryo 16-18hr		(61)
embryo 18-20hr		(50)
embryo 20-22hr		(29)
embryo 22-24hr		(28)
larva L1		(29)
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		(34)
white prepupae new		(38)
white prepupae 12hr		(31)
white prepupae 24hr		(60)
pupae 2d postWPP		(111)
pupae 3d postWPP		(61)
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		65
embryo 12-14hr		59
embryo 14-16hr		76
embryo 16-18hr		61
embryo 18-20hr		50
embryo 20-22hr		29
embryo 22-24hr		28
larva L1		29
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		34
white prepupae new		38
white prepupae 12hr		31
white prepupae 24hr		60
pupae 2d postWPP		(111)
pupae 3d postWPP		61
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		65
embryo 12-14hr		59
embryo 14-16hr		76
embryo 16-18hr		61
embryo 18-20hr		50
embryo 20-22hr		29
embryo 22-24hr		28
larva L1		29
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		34
white prepupae new		38
white prepupae 12hr		31
white prepupae 24hr		60
pupae 2d postWPP		111
pupae 3d postWPP		61
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		65
embryo 12-14hr		59
embryo 14-16hr		76
embryo 16-18hr		61
embryo 18-20hr		50
embryo 20-22hr		29
embryo 22-24hr		28
larva L1		29
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		34
white prepupae new		38
white prepupae 12hr		31
white prepupae 24hr		60
pupae 2d postWPP		111
pupae 3d postWPP		61
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		(65)
embryo 12-14hr		(59)
embryo 14-16hr		(76)
embryo 16-18hr		(61)
embryo 18-20hr		(50)
embryo 20-22hr		29
embryo 22-24hr		28
larva L1		29
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		(34)
white prepupae new		(38)
white prepupae 12hr		31
white prepupae 24hr		(60)
pupae 2d postWPP		(111)
pupae 3d postWPP		(61)
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		65
embryo 12-14hr		59
embryo 14-16hr		76
embryo 16-18hr		61
embryo 18-20hr		50
embryo 20-22hr		29
embryo 22-24hr		28
larva L1		29
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		34
white prepupae new		38
white prepupae 12hr		31
white prepupae 24hr		60
pupae 2d postWPP		111
pupae 3d postWPP		61
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		1
embryo 02-04hr		2
embryo 04-06hr		2
embryo 06-08hr		11
embryo 08-10hr		23
embryo 10-12hr		65
embryo 12-14hr		59
embryo 14-16hr		76
embryo 16-18hr		61
embryo 18-20hr		50
embryo 20-22hr		29
embryo 22-24hr		28
larva L1		29
larva L2		21
larva L3 12hr old		18
larva L3 puffstage 1-2		11
larva L3 puffstage 3-6		18
larva L3 puffstage 7-9		34
white prepupae new		38
white prepupae 12hr		31
white prepupae 24hr		60
pupae 2d postWPP		111
pupae 3d postWPP		61
pupae 4d postWPP		11
adult male 01day		15
adult male 05day		14
adult male 30day		15
adult female 01day		12
adult female 05day		7
adult female 30day		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		16
Schneider line 2 Sg4		13
embryonic 1182-4H		9
embryonic GM2		9
embryonic Kc167		4
embryonic S1		3
embryonic S3		25
leg disc CME L1		8
wing disc CME-W2		8
wing disc ML-DmD8		11
wing disc ML-DmD9		14
wing disc ML-DmD16-c3		8
wing disc ML-DmD21		10
wing disc ML-DmD32		19
haltere disc ML-DmD17-c3		24
eye-antennal disc ML-DmD11		13
antennal disc ML-DmD20-c5		9
mixed discs ML-DmD4-c1		16
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		6
tumorous blood cells mbn2		14
ovary fGS/OSS		9
ovary OSC		4
ovary OSS		3
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		14
cold shock, 4-day adult		13
heat shock, 4-day adult		5
Cadmium 50 mM 6 hrs, larvae L3		11
Cadmium 50 mM 12 hrs, larvae L3		10
Cadmium 50 mM 48 hrs, 4-day adult		6
Cadmium 100 mM 48 hrs, 4-day adult		4
Copper 0.5 mM 12 hrs, larvae L3		9
Copper 15 mM 48 hrs, 4-day adult		4
Zinc 5 mM 12 hrs, larvae L3		7
Zinc 4.5 mM 48 hrs, 4-day adult		6
Ethanol 2.5% 3 hrs, larvae L3		6
Ethanol 5% 3 hrs, larvae L3		7
Ethanol 10% 3 hrs, larvae L3		9
Caffeine 1.5 mg/ml 4 hrs, larvae L3		7
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		4
Caffeine 25 mg/ml 48 hrs, 4-day adult		8
Paraquat 5 mM 48 hrs, 4-day adult		5
Paraquat 10 mM 48 hrs, 4-day adult		7
Rotenone 2 μg 12 hrs, larvae L3		9
Rotenone 8 μg 12 hrs, larvae L3		11
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

mE2_34_mRNA_expression_cluster_29

External Data & Images

Show all FlyExpress processed images for CRMP

BDGP expression data

•

PC00268

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0023023

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG1411-RD;CG1411-RC;CG1411-RD;CG1411-RC;CG1411-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Stages(s) 13-16

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

viable, with Scer\GAL4^pnr-MD237

CRMP^GD4716

Sterility

Allele

fertile

Other Phenotypes

Allele

chemical sensitive (with Df(3R)noi-B)

circadian behavior defective

CRMP^EP3238

circadian behavior defective (with CRMP^supIa1)

CRMP^supK1

circadian behavior defective (with CRMP^supK1)

CRMP^supIa1

circadian behavior defective (with Df(3R)noi-B)

circadian behavior defective | recessive

CRMP^supK1

memory defective

memory defective (with CRMP^supIa1)

CRMP^supK1

memory defective (with CRMP^supK1)

CRMP^supIa1

Phenotype manifest in

Allele

Classical Alleles ( 14 )

For All Classical Alleles Show

Allele of CRMP	Mutagen	Stocks	Known lesion
CRMP^supA4	ethyl methanesulfonate	2	Yes
CRMP^supK1	hexamethylphosphoramide	2	Yes
CRMP^d08876	P-element activity	1	--
CRMP^EP3238	P-element activity	1	--
CRMP^EY04380	P-element activity	1	--
CRMP^f05232	piggyBac transposase	1	--
CRMP^KG02006		1	--
CRMP^MI06892		1	--
CRMP^supI2	Delta2-3	1	Yes
CRMP^supIa1	P-element activity	1	Yes
CRMP^UM-8382-3		1	--
CRMP^DG06812		0	--
CRMP^supB3	Delta2-3	0	Yes
CRMP^supI3	Delta2-3	0	Yes

Alleles Carried on Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CRMP	Mutagen	Stocks	Known lesion
CRMP^+t10.8	in vitro construct - genomic fragment	1	Yes
CRMP^{fs9a.T:Avic\GFP-EGFP}	in vitro construct - deletion	1	Yes
CRMP^{fs9b.T:Avic\GFP-EGFP}	in vitro construct - deletion	1	Yes
CRMP^GD4716	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CRMP^HM05269	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CRMP^KK108924	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CRMP^{T:Avic\GFP-EGFP}	in vitro construct - coding region fusion	1	Yes
CRMP^NIG.1411R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
CRMP^{supK1.T:Avic\GFP-EGFP}	in vitro construct - site directed mutagenesis	0	Yes

Aneuploid Aberrations

Disrupted in

Df(3R)Exel6144

(Ryder, 2004.4.26)

Df(3R)noi-B

(Rawls, 2006)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

characterization construct

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EP}CRMP^EP3238

P{EPgy2}CRMP^EY04380

P{XP}CRMP^d08876

miscellaneous insertions

Mi{MIC}CRMP^MI06892

P{RS3}CRMP^UM-8382-3

P{SUPor-P}CRMP^KG02006

P{wHy}CRMP^DG06812

PBac{WH}CRMP^f05232

Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )

Terms Based on Experimental Evidence ( 4 terms )

Molecular Function

CV term

dihydropyrimidinase activity

References

inferred from direct assay

(Morris et al., 2012)

Biological Process

CV term

'de novo' pyrimidine nucleobase biosynthetic process

References

inferred from genetic interaction with r

(Rawls, 2006)

memory

inferred from mutant phenotype

(Morris et al., 2012)

Ras protein signal transduction

inferred from genetic interaction with Ras85D

(Morris et al., 2012)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 3 terms )

Molecular Function

CV term

dihydropyrimidinase activity

References

inferred from sequence or structural similarity with UniProtKB:Q63150

(FlyBase, 1992-)

non-traceable author statement

(Gojkovic, 2002.1.7)

Biological Process

CV term

pyrimidine nucleobase catabolic process

References

inferred from electronic annotation with InterPro:IPR011778

(FlyBase Curators et al., 2004-)

Cellular Component

CV term

(FlyBase Curators et al., 2004-)

References

cytoplasm

inferred from electronic annotation with InterPro:IPR011778

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CRMP allele

Gene

References

CRMP^EP3238

pnr

(Pena-Rangel et al., 2002)

unspecified

(Rawls, 2006)

External Data

y¹ w^67c23; P{EPgy2}CRMP^EY04380

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0023023

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

40675

Orthologs

OrthoDB Orthologs (78) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6XD49Q

Dipteran inclusive ortholog search

EOG65X849

Insect inclusive ortholog search

EOG6WWQDK

Arthropod inclusive ortholog search

EOG68932G

Metazoa inclusive ortholog search

EOG68SVM5

Orthologs in Drosophila Species (EOG6XD49Q)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA12765

Drosophila persimilis

Dper\GL22308

Drosophila willistoni

Drosophila virilis

Drosophila virilis

Drosophila virilis

Drosophila mojavensis

Dmoj\GI20644

Drosophila mojavensis

Dmoj\GI23638

Drosophila grimshawi

Dgri\GH15883

Drosophila grimshawi

Dgri\GH20890

Orthologs in non-Drosophila Dipterans (EOG65X849)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL007633

Anopheles gambiae

Malaria mosquito

Agam\AGAP003124

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ010151

Orthologs in non-Dipteran Insects (EOG6WWQDK)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\LOC100578817

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG014607

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH17821

Atta cephalotes

Leafcutter ant

Acep\ACEP21618

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO22556

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL19503

Linepithema humile

Argentine ant

Lhum\LH17340

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB14579

Solenopsis invicta

Red fire ant

Sinv\SINV16737

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI002925

Bombyx mori

Silkmoth

Bmor\BGIBMGA005717

Pediculus humanus

Human body louse

Phum\PHUM513380

Tribolium castaneum

Red flour beetle

Tcas\TC010876

Orthologs in non-Insect Arthropods (EOG68932G)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\JGI_V11_202613

Ixodes scapularis

Deer tick

Isca\ISCW010603

Ixodes scapularis

Deer tick

Isca\ISCW019633

Ixodes scapularis

Deer tick

Isca\ISCW017775

Orthologs in non-Arthropod Metazoa (EOG68SVM5)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\dhp-1

Caenorhabditis elegans

Nematode

Cele\dhp-2

Caenorhabditis elegans

Nematode

Cele\unc-33

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_025325gn

Danio rerio

Zebrafish

Drer\crmp1

Danio rerio

Zebrafish

Drer\dpysl5b

Danio rerio

Zebrafish

Drer\ENSDARG00000038974

Danio rerio

Zebrafish

Drer\dpysl5a

Danio rerio

Zebrafish

Drer\dpysl2b

Danio rerio

Zebrafish

Drer\dpysl3

Danio rerio

Zebrafish

Drer\dpysl4

Danio rerio

Zebrafish

Drer\dpys

Xenopus tropicalis

Western clawed frog

Xtro\ENSXETG00000034346

Xenopus tropicalis

Western clawed frog

Xtro\dpysl5

Xenopus tropicalis

Western clawed frog

Xtro\dpys

Xenopus tropicalis

Western clawed frog

Xtro\dpysl4

Xenopus tropicalis

Western clawed frog

Xtro\crmp1

Xenopus tropicalis

Western clawed frog

Xtro\dpysl3

Xenopus tropicalis

Western clawed frog

Xtro\ENSXETG00000031639

Gallus gallus

Domestic chicken

Ggal\CRMP1B

Gallus gallus

Domestic chicken

Ggal\DPYSL4

Gallus gallus

Domestic chicken

Ggal\CRMP2A

Gallus gallus

Domestic chicken

Ggal\DPYS

Gallus gallus

Domestic chicken

Ggal\DPYSL3

Mus musculus

House mouse

Mmus\Dpysl4

Mus musculus

House mouse

Mmus\Crmp1

Mus musculus

House mouse

Mmus\Dpys

Mus musculus

House mouse

Mmus\Dpysl2

Mus musculus

House mouse

Mmus\Dpysl3

Mus musculus

House mouse

Mmus\Dpysl5

Rattus norvegicus

Norway rat

Rnor\Dpysl2

Rattus norvegicus

Norway rat

Rnor\Dpys

Rattus norvegicus

Norway rat

Rnor\Dpysl5

Rattus norvegicus

Norway rat

Rnor\ENSRNOG00000018992

Rattus norvegicus

Norway rat

Rnor\Crmp1

Rattus norvegicus

Norway rat

Rnor\Dpysl4

Homo sapiens

Human

Hsap\DPYSL2

Homo sapiens

Human

Hsap\DPYSL3

Homo sapiens

Human

Hsap\CRMP1

Homo sapiens

Human

Hsap\DPYSL5

Homo sapiens

Human

Hsap\DPYSL4

Homo sapiens

Human

Hsap\DPYS

Human Orthologs (6)

Gene

OMIM

HGNC

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA12765

Drosophila persimilis

Dper\GL22308

Drosophila willistoni

Dwil\GK22508

Drosophila virilis

Dvir\GJ24714

Drosophila mojavensis

Dmoj\GI20644

Drosophila grimshawi

Dgri\GH15883

Stocks & Reagents

Stocks Listed in FlyBase ( 18 )

Bloomington

40955

w^*; CRMP^supIa1

40953

w¹¹¹⁸; P{EP}CRMP^EP3238

40954

w^*; b¹; CRMP^supK1

19693

40958

w^*; b¹; P{PYDGFPfs9a}1a CRMP^supK1

24477

w^*; b¹; kni^ri-1 CRMP^supA4 p^p

40956

w^*; P{PYD2GFP}1d; kni^ri-1 CRMP^supA4 p^p

124513

w¹¹¹⁸; P{RS3}CRMP^UM-8382-3

VDRC

v101510

P{KK108924}VIE-260B

v15320

w¹¹¹⁸; P{GD4716}v15320

More stocks available...

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 106 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

FI04515

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

DRSC - Results from RNAi screens.

•

FBgn0023023

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

40675

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for identity of: CRMP CG1411

(Zheng, 1999.11)

Source for database merge of

Source for merge of: CRMP BcDNA:HL02693

Source for merge of: CRMP EP3238

Additional comments

Source for merge of CRMP BcDNA:HL02693 was sequence comparison (date:000129).

Source for merge of CRMP EP3238 was that EP3238 insertion is within CRMP (and in the right orientation) (date:040519).

Other Comments

Identification: Sequence similarity to chick CRMP-62.

Mutants show numerous defects in axon outgrowth in both central and motor projections, suggestive of a defect in pathfinding specificity.

(Morris et al., 2012, Keleman et al., 2009.8.5, Perkins et al., 2009)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

Entrez Gene - A searchable database of RefSeq genes.

•

40675

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Amidohydrolase 1 (IPR006680)

Metal-dependent hydrolase, composite domain (IPR011059)

Hydantoinase/dihydropyrimidinase (IPR011778)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

PC00268

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0023023

DRSC - Results from RNAi screens.

•

FBgn0023023

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0023023

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG1411-RD;CG1411-RC;CG1411-RD;CG1411-RC;CG1411-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0023023

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

40675

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

40675

modMine - Data generated by the modENCODE project.

•

FBgn0023023

Synonyms & Secondary IDs ( 16 )

Reported As

Symbol Synonym

BcDNA:HL02693

CG1411

CRMP

(Morris and Rawls, 2007, Wiggin et al., 2005, Rawls, 2006, FlyBase Curators, 2008, Hazelett et al., 2012, Morris et al., 2012, Beckstead et al., 2005, Morris et al., , Danchin and Pontarotti, 2004, Japanese National Institute of Genetics, 2012.5.21, Borycz et al., 2012)

crmp

(Morris and Rawls, 2007, Morris and Rawls, 2008)

DHP

(Morris and Rawls, 2007)

EP3238

EP(3)3238

(Pena-Rangel et al., 2002)

l(3)83Ba

Pyd2

(Gojkovic, 2002.1.7)

pyd2

(Borycz et al., 2012)

unnamed